WO2019153968A1 - 配置调节生物节律光照装置发光参数的方法及装置 - Google Patents

配置调节生物节律光照装置发光参数的方法及装置 Download PDF

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Publication number
WO2019153968A1
WO2019153968A1 PCT/CN2018/125529 CN2018125529W WO2019153968A1 WO 2019153968 A1 WO2019153968 A1 WO 2019153968A1 CN 2018125529 W CN2018125529 W CN 2018125529W WO 2019153968 A1 WO2019153968 A1 WO 2019153968A1
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Prior art keywords
parameter set
parameter
user
illumination device
illumination
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PCT/CN2018/125529
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English (en)
French (fr)
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马君显
马捷
赵滢滢
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深圳市慧智生命科技有限公司
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Publication of WO2019153968A1 publication Critical patent/WO2019153968A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0618—Psychological treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M1/00—Substation equipment, e.g. for use by subscribers
    • H04M1/72—Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
    • H04M1/724—User interfaces specially adapted for cordless or mobile telephones
    • H04M1/72403—User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B45/00—Circuit arrangements for operating light-emitting diodes [LED]
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B45/00—Circuit arrangements for operating light-emitting diodes [LED]
    • H05B45/10—Controlling the intensity of the light
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B45/00—Circuit arrangements for operating light-emitting diodes [LED]
    • H05B45/20—Controlling the colour of the light
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B47/00—Circuit arrangements for operating light sources in general, i.e. where the type of light source is not relevant
    • H05B47/10—Controlling the light source
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B47/00—Circuit arrangements for operating light sources in general, i.e. where the type of light source is not relevant
    • H05B47/10—Controlling the light source
    • H05B47/105—Controlling the light source in response to determined parameters
    • H05B47/11—Controlling the light source in response to determined parameters by determining the brightness or colour temperature of ambient light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0626—Monitoring, verifying, controlling systems and methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645—Applicators worn by the patient
    • A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
    • A61N2005/0648—Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A61N2005/0652—Arrays of diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
    • Y02B20/00—Energy efficient lighting technologies, e.g. halogen lamps or gas discharge lamps
    • Y02B20/40—Control techniques providing energy savings, e.g. smart controller or presence detection

Definitions

  • the present invention relates to the field of medical devices, and more particularly to a method and apparatus for configuring illumination parameters for adjusting a biological rhythm illumination device.
  • Human biological rhythm disorders are highly correlated with many diseases, such as AD (Alzheimer's disease), Parkinson's disease, depression, insomnia, etc. These diseases not only bring pain to the patients themselves and their families, but also cause a serious burden on society. Due to the complex causes of human biological rhythm disorders and the variety of diseases caused, although medical research institutions and pharmaceutical factories around the world have been working hard, so far, the medical treatment of biological rhythm disorders and most of the diseases caused by them are still at Awkward situation. The Opto-genetics study, which has begun to emerge in recent years, has found that the emission of certain characteristic light signals into the fibers of mouse brain tissue and even into the eyes of mice can significantly adjust the dysregulation of the body. Certain biological rhythms, which cause signs of cure for certain diseases associated with these rhythms.
  • the Massachusetts Institute of Technology Li-Huei Tsa is equivalent to a paper published in Nature in 2016, which emits LED light with a certain characteristic to the eyes of the fiber and AD mouse implanted in the brain of AD rats, one hour a day. After one month of continuous measurement, it was found that the original turbulent EEG wave of the AD mouse reproduces the periodic rhythm, and the identification of some of the industry-recognized AD symptoms such as A ⁇ protein and Tau protein in the brain tissue of the mouse is found. Sex indicators have returned to normal levels.
  • the technical forms used are different, but the principle is basically the same, that is, using light to stimulate the human retina can effectively inhibit the secretion of melatonin in the human body, thereby adjusting the function of the human body clock.
  • any device that uses this type of technology can work to some extent.
  • the illuminating parameters in the prior art are all set in advance.
  • Several modes can't be modified according to the lighting effect, and can't be modified according to the different situations of the specific users. Therefore, the adaptability is poor, the effect is not good, and the user may be visually damaged.
  • the technical problem to be solved by the present invention is that, in view of the above-mentioned shortcomings of poor adaptability, poor effect, and possible visual damage, the present invention provides a better adaptability, better effect, and the ability to visualize.
  • the technical solution adopted by the present invention to solve the technical problem thereof is: constructing a method for configuring a lighting parameter for adjusting a biological rhythm illumination device, comprising the following steps:
  • the server verifies the registered user identity information and the identity information of the illumination device, and matches the user's illumination record and the latest detection data;
  • step C) further includes the following steps:
  • step D) further includes:
  • the method further includes the following steps:
  • the user health status data includes, but is not limited to, data such as a sleep time, a deep sleep time, and a duration obtained by a wristband, a watch, or the like that continuously detects a 24-hour pulse, a breath, or the like, according to data such as a pulse, a breath, and the like;
  • the method further includes the following steps:
  • the illumination device emits light for a certain time interval
  • the brain wave of the user is collected and processed by the brain wave collecting device, and parameters of the set components are obtained and uploaded to the server.
  • the parameters in the parameter set include: central wavelength and its spectral components, light intensity, spectral power density, time modulation frequency of light intensity, time modulation duty ratio of light intensity, luminescence position and/or light emission And an end time;
  • the parameter value of the set component of the electroencephalogram includes, but is not limited to, a frequency value corresponding to a maximum power spectral density corresponding to a beta wave or a gamma wave in the brain wave.
  • the corresponding parameter adjustment in the step D1) includes comparing a frequency value corresponding to the maximum power spectral density corresponding to the ⁇ wave or the ⁇ wave with a time modulation frequency of the light intensity in the parameter set, if The deviation is made by resetting the time modulation frequency of the light intensity until the difference between the two frequencies is equal or less than a set value.
  • the setting rule in the step D3) includes: comparing the sleep start time measured by the peripheral device with the ideal sleep start time set by the user, and if there is a deviation, adjusting the blue light according to the deviation equivalent value The LED illumination start time, reminding the user by pop-up information, and obtaining user approval until the sleep start time measured by the peripheral is equal to the ideal sleep time set by the user, or less than a certain set value recognized by the user. ;as well as
  • the duration of the deep sleep is compared with the duration set by the user. If not, the blue light intensity and/or the duration of the illumination device are appropriately adjusted according to a preset adjustment procedure until the deep sleep measured by the peripheral device The duration is equal to or greater than the length of time set by the user.
  • the invention also relates to an apparatus for implementing the above method, comprising:
  • a login unit configured to log in to the server on the application of the mobile terminal, to connect the application to the communication module on the illumination device, obtain identity information and configuration status of the illumination device, and forward the same to the server;
  • the authentication unit is configured to: after the server verifies the login user identity information and the identity information of the illumination device, and match the user's illumination record and the latest detection data;
  • a parameter set selection unit configured to select a corresponding parameter set type in a preset plurality of types of parameter sets according to the detection data; and select the closest one parameter among the selected parameter set types according to the illumination record set;
  • a parameter set adjustment unit configured to send the obtained optical parameter set to the mobile terminal after performing the individual adjustment confirmation on the selected parameter set, and configured to the illumination device by using a communication module of the illumination device
  • the illumination device uses the parameter set to drive the illumination unit to emit light.
  • parameter set selection unit further includes:
  • a special parameter set judging module configured to detect whether a special parameter set is stored for the user, if yes, obtain the special parameter set and replace the previously selected parameter set; if not, still use the previously selected parameter set;
  • the parameter set adjustment unit further includes:
  • the adjustment module is configured to detect whether the user uploads a parameter value of the current brain wave setting component, and if yes, adjusts the corresponding parameter in the parameter set according to the parameter value, and performs the next step; if not, directly Perform the next step;
  • a sending module configured to send the obtained parameter set as a configuration parameter set to the mobile terminal
  • Brain wave acquisition and processing unit for collecting and processing the brain wave of the user through the brain wave collecting device after the illumination device emits light, continuously obtaining the parameter values of the set components and uploading to the server .
  • the method and apparatus for implementing the configuration of the present invention for adjusting the illuminating parameters of the biological rhythm illumination device have the following beneficial effects: due to the use of the application login, the information provided for the user individual in the registration and the configuration information uploaded during the illumination are illuminated. It is possible to optimize the parameters in the parameter set, so that the light parameters obtained by the user after each login can be the light parameter set most suitable for its current state; at the same time, the introduction of the brain wave enables the previous illumination even during the irradiation process. The effect of the light parameter adjustment, which makes it more adaptable, better, and can reduce the possibility of visual damage.
  • FIG. 1 is a flow chart of a method and apparatus embodiment of the present invention for adjusting a lighting parameter of a biological rhythm illumination device
  • Figure 2 is a schematic structural view of the system in the embodiment
  • Figure 3 is a schematic view showing the structure of the apparatus in the embodiment.
  • the method for adjusting a lighting parameter of a biological rhythm illumination device includes the following steps:
  • Step S11 Logging in to the server:
  • a system including an illumination device that adjusts the biological rhythm is taken as an example to describe a configuration process of the illumination parameters of the device.
  • the general structure of the system is shown in Fig. 3, which includes a server, a mobile terminal, an illumination device, and a brain wave processing device.
  • the server is configured to store user data, including user registration data and various data after the user uses illumination, for example, brain wave data and data obtained during the test; the server connects to the application running on the mobile terminal through the network, and receives the application.
  • the data uploaded by the program is processed and stored correspondingly, and the data is also sent to the application;
  • the illumination device generates and outputs a light beam according to the illumination parameters transmitted to the mobile terminal, and sets the part of the human body (for example, the pupil The non-visual area is irradiated;
  • the electroencephalogram processing apparatus receives the brain wave of the user irradiated by the light beam, and processes the brain wave to obtain a parameter value of the set component therein, and uploads the parameter value to the mobile terminal through the mobile terminal
  • the determination of identity is very important. For example, when brainwave data is uploaded, the server needs to know which user the data belongs to; and when the lighting parameters are issued, it is also necessary to know that the data is suitable for that user.
  • the user logs in to the server on the application of the mobile terminal, causes the application to connect with the communication module on the illumination device, acquires the identity information and configuration status of the illumination device, and forwards the configuration to The server;
  • the identity information may include identity information of the user, for example, a name used in registration, etc.; and may also include identity information of the lighting device, for example, hardware identification of the lighting device Codes, etc.; may also include binding information of user information and lighting device identity information, and the like.
  • Step S12 verifying the identity information, and obtaining the user data: in this step, the server verifies the registered user identity information and the identity information of the illumination device, and matches the user's illumination record and the latest one. Detecting data; that is, in this step, the server can verify the multiple identity information, and finally confirm that the user is a legitimate user, and find the user's previous registration information and history of light exposure in the database. Data, including its evaluation of results obtained after regular, on-site testing, and so on.
  • Step S13 selecting a parameter set type and a parameter set: in this step, selecting a corresponding parameter set type in a preset plurality of types of parameter sets according to the detection data; and selecting the parameter set according to the illumination record Selecting the closest one of the parameter sets; in particular, because of the type of the illumination device itself and the types of biological rhythms that can be adjusted for each illumination device, each type of illumination parameter is different, therefore,
  • the illuminating parameters are divided into multiple types according to the adjusted biological rhythm type, and in each type, according to the set situation, for example, the degree of severity or the degree of a certain index, it is divided into a plurality of parameter sets; each The parameter set includes all parameters of the biological rhythm of the category in which the illumination device of the type is adjusted.
  • the illumination device When the parameter set is transmitted to the illumination device, the illumination device directly configures the parameters in the parameter set, and the parameter set can be issued. Defined beam of light, the specified part of the illumination, usually a non-visual area, for a safe and effective biological rhythm Regulation.
  • this step in some cases, there may be a special parameter set for the individual, for example, an irradiation plan or suggestion proposed by a doctor or an expert recognized by the user for the user's test result.
  • a special parameter set for example, an irradiation plan or suggestion proposed by a doctor or an expert recognized by the user for the user's test result.
  • Step S14 performs individual adjustment on the parameter set, and outputs the parameter set directly to the illumination device: although the parameter set obtained above can be directly used, it also has a certain effect. However, since the parameter set is determined for the degree of an indicator, there is still room for some of the parameters to be fine-tuned for the individual. This fine tuning can enhance the effect of this parameter set on the individual. Therefore, in this step, after performing the individual adjustment confirmation on the selected parameter set, the obtained optical parameter set is sent to the mobile terminal, and is configured to the illumination device by the communication module of the illumination device. The illumination device uses the parameter set to drive the illumination unit to emit light. In some cases, the parameter set obtained in the above step may be directly sent to the illumination device without performing fine adjustment of the individual parameters. Although this operation saves some steps, it may not work well. However, in some cases, for example, the absence of individual data, the absence of relevant exposure data, etc., is also an acceptable alternative.
  • step S14) can be repeatedly executed according to the set time interval, so that the parameter adjustment can be performed at any time according to the effect of the illumination during the illumination process, in order to obtain a better illumination effect.
  • the system includes an electroencephalogram processing device that acquires and processes a user's brain wave before or during the illumination, and continuously obtains a parameter value of the set component and passes the parameter value.
  • the mobile terminal uploads to the server.
  • the corresponding parameter of the parameter set currently used by the user is adjusted, so that the user's biological rhythm and the illumination achieve a similar "resonance" relationship, and further Get better adjustment. Therefore, in the present embodiment, the individual parameters of the parameter set can also be individually adjusted during the illumination process.
  • step S21 the processed brain wave data is input No. If no, the process goes to step S24; if yes, the next step is performed; in this step, it is determined whether or not brain wave data is input through the mobile terminal.
  • Step S22 acquires the set component parameter value in the electroencephalogram data:
  • the parameter value of the electroencephalogram setting component is extracted from the data uploaded by the mobile terminal.
  • Step S23 adjusts the corresponding parameter in the selected parameter set to be the above-mentioned set component value adaptation: in this step, the corresponding parameter in the parameter set is adjusted according to the parameter value of the set component of the brain wave obtained above.
  • the time modulation frequency of the light intensity in the parameter set is made close to or equal to the frequency of the received ⁇ wave or ⁇ wave according to the frequency value of the ⁇ wave or the ⁇ wave in the brain wave data.
  • Step S24 outputs the selected parameter set: In this step, the above-mentioned parameter set adjusted by the individual or not individually adjusted is output.
  • the parameters in the parameter set include: a central wavelength and a spectral component thereof, a light intensity, a spectral power density, a time modulation frequency of the light intensity, a time modulation duty ratio of the light intensity, a luminescence position and/or a light emission and an end time; a parameter value of the set component of the electroencephalogram includes a frequency value of a ⁇ wave or a ⁇ wave therein; and a corresponding parameter corresponding to a set component in the brain wave includes light The time modulation frequency of the intensity.
  • the above parameters may be adjusted according to the user's biological rhythm during or after illumination, and the adjustment may be for a parameter set in a parameter set in advance.
  • the aforementioned parameter set is adjusted according to the characteristics of the user's brain waves during illumination.
  • the corresponding parameter adjustment includes: a frequency value corresponding to a maximum power spectral density corresponding to the ⁇ wave or the ⁇ wave and a light intensity in the parameter set.
  • the parameters for which adjustment is made when lighting for a symptom may be different.
  • the steps of parameter adjustment are performed according to a set rule, and the setting rule includes: comparing a sleep start time measured by the peripheral with an ideal sleep start time set by the user, If there is a deviation, the blue LED illumination start time is adjusted according to the deviation equivalent value, and the start time is reminded to the user by pop-up information, and the user is recognized until the sleep start time measured by the peripheral is equal to the ideal sleep set by the user.
  • the time, or less than a certain set value approved by the user; in addition, the duration of the deep sleep can be compared with the duration set by the user, and if not, the blue light of the illumination device is appropriately adjusted according to a preset adjustment procedure. Intensity and/or duration of illumination until the length of deep sleep measured by the peripheral is equal to or greater than the length of time set by the user.
  • the illumination device comprises a device frame designed to be suitable for wearing on the face of the person, a control module on the device frame, a light modulation module, a plurality of LED light groups, a communication module, and ambient light. Sensors, power modules, etc.
  • the control module includes a core processor and a simple input button, which are directly connected to the light modulation module, the communication module, the ambient light sensor, and the power module, and are indirectly connected with the plurality of LED light groups, thereby realizing the function of the whole device in real time.
  • the light modulation module controls specific optical parameters output by the plurality of LED light groups; the plurality of LED light groups are driven by the light modulation module to emit light that meets a set parameter; the communication module Providing a connection channel, which is connected to the smart device APP (ie, an application on the mobile terminal); the ambient light sensor transmits the device background light information collected in real time to the control module to assist in adjusting the light modulation module; The module is regulated by the control module for powering the entire human biological rhythm adjustment device.
  • the above device frame adopts a full-frame eyeglass shape.
  • the profile of the glasses is slightly larger than that of the conventional glasses used in the existing market. It not only supports the user to use without glasses, but also supports the user to use the glasses when they are worn, without affecting the normal use effect.
  • the device frame is designed to meet the usage of different users, expand the scope of use, and improve the usability and effectiveness of the device.
  • the LED light group is disposed at a relative upper and lower positions of the mirror ring of the device frame, and the LED light group may be one or two or three or four or five or six or seven or eight groups. Each of the LED light groups includes one or two or three LED lights, and the front end of the illuminant of the LED light group reaches a distance of 12-16 mm from the iris of the human eye.
  • the distance from the front end of the illuminant of the LED lamp group to the iris of the human eye is about 14 mm. It can effectively control the stimulation of the retina around the human eye. Since multiple sets of LED light groups are respectively illuminated according to different regions, the power density distribution is reduced, and the light damage is reduced; multiple LED light groups can realize multi-wavelength combination, increase the range of stimulation, and combine multi-color light to reduce the monochromatic light to the visual area stimulation. Discomfort caused. Effectively achieves illumination to the surrounding retina without affecting normal vision. Provides a substantially uniform illumination and allows for a range of eye movements, such as large eyes or rotation. In this embodiment, the effective light intensity of the corneal surface is in the range of 8-8000 lux, and the optical power incident from the pupil is in the range of 8-800 uW/cm.
  • Each LED tube tip (ie, the LED light-emitting surface) of the plurality of LED lamp groups is inclined at a certain angle to the pupil to avoid directing the macular area, and at the same time ensuring effective illumination of different regions of the peripheral retina including the nasal region and the lateral region without affecting normal Vision.
  • Each of the LEDs in the LED light group is highly directional. Generally, it is a pointed epoxy package, or with a metal reflective cavity package, or a concentrating lens, and no scattering agent, the illuminating angle is 15 degrees -20 degrees, ensuring that the pupil does not leave the LED light group after the activity. Range while preventing excessive stray light from illuminating near the eyes. It can be considered that the diameter of the spot on the surface of the iris is substantially equal to the diameter of the iris.
  • the light modulation module adopts light modulation and spectral mixing to enable the LED light group to output light of different wavelengths and different wavelengths at different times, and multiple sets of the LED light groups can realize different combinations of light forming a composite at the pupil.
  • the specific light parameter of the light modulation module controlling the LED light group output includes a time frequency, an illumination intensity, and a duty ratio, and the modulation effect includes a wavelength combination, a frequency combination, and an intensity combination, and the light modulation module controls the LED
  • the specific optical parameters of the output of the light group include a time modulation frequency, a wavelength modulation, an intensity modulation, and a duty cycle modulation of the single group of the LED light groups, and the specific light parameters of the light modulation module controlling the LED light group output include multiple groups.
  • the light modulation module can modulate a plurality of groups (for example, 2-8 groups) of the LED lamp group and the background light for depth modulation, color temperature modulation, and power modulation, the depth modulation In the range of 0-100%.
  • the light modulation module 11 controls specific optical parameters of the plurality of LED light groups, and the specific modulation modes mainly include: time frequency, luminous intensity, and duty ratio; the final modulation effect is: wavelength combination, frequency combination, and intensity combination. .
  • the light modulation module controls specific optical parameters output by the plurality of groups of LED light groups, including realizing time modulation frequency, wavelength modulation, intensity modulation, duty cycle modulation, and deep modulation of multiple sets of LED lights of a single group of LED lamps, Color temperature modulation, power modulation.
  • the modulated light is within the acceptable range of the human eye and meets the routine needs of photobiology research, including the latest data showing a fixed frequency of 40 Hz blue light that may have a greater impact on AD patients (Alzheimer's disease patients).
  • the smart device or the mobile terminal is a smart phone, and must have a Bluetooth communication module, and ensure that there is enough storage space to load and run the mobile phone APP.
  • Smartphones whose operating systems can include commonly used Windows, Android, Apple IOS, and the like.
  • the APP provides users with a series of common language interfaces such as login, registration, authentication, and evaluation, which are convenient for users to use; and have universal communication interfaces such as Wi-Fi and 4G to communicate with the cloud server. Users can register personal information including the condition information to be adjusted, fill out the professional scale for disease assessment, share and communicate with other users, and so on.
  • the light-spot device has a mechanical switch, which allows the user to use the human biological rhythm adjustment device only by opening and closing the switch without logging in to the cloud server, but the formula used at this time is The data downloaded during the second login; the system supports uploading the last usage information when logging in next time.
  • the above one parameter set can be regarded as a kind of "lighting formula", which is classified according to different adaptation symptoms, and each category can include a plurality of such parameter sets.
  • an adaptive symptom e.g. AD
  • four parameter sets can be included, as follows
  • 3 4 blue LEDs on the outside of the nose of the left and right eyes, each of which has a modulation frequency of 40 Hz, a wavelength of 463 nm, a duty ratio of 40%, and a power of 2 mW; the red LEDs at the same position and at the same position of the LEDs emit light, and each LED
  • the modulation frequency is 0 Hz
  • the wavelength is 675 nm
  • the power is 1 mW.
  • the formula is mixed with red light and blue light, which can reduce the tingling sensation caused by pure blue light irradiation on the retinal visual area, and does not weaken the stimulating effect of blue light on the non-visual area of the retina;
  • the system will recommend the appropriate lighting “recipe” to the user through the optimization algorithm according to the user's personal situation, and automatically open the adjustment unit through the APP.
  • the treatment data is sent to the cloud server through the APP, including start time and end time, recipe, etc.; at the same time, the human biological rhythm adjustment device records the illumination "recipe" selected by the user. At the same time, these recorded information will be saved in the user's smart device and synchronized to the cloud server registrant's name.
  • another parameter set under the classification of symptoms can also include four types, as follows:
  • 3 4 blue LEDs on the outside of the nose of the left and right eyes, each of which has a modulation frequency of 0 Hz, a wavelength of 465 nm, a duty ratio of 40%, and a power of 2 mW; the red LEDs at the same position and at the same position of the LEDs emit light, and each LED
  • the modulation frequency is 0 Hz
  • the wavelength is 675 nm
  • the power is 1 mW.
  • the formula is mixed with red light and blue light, which can reduce the tingling sensation caused by pure blue light irradiation on the retinal visual area, and does not weaken the stimulating effect of blue light on the non-visual area of the retina;
  • each LED Only the upper two blue LEDs emit light on the outside of the nose of the left and right eyes.
  • the modulation frequency of each LED is 0 Hz
  • the wavelength is 465 nm
  • the duty ratio is 40%
  • the power is 2 mW.
  • a total of 2 red LEDs are located at the same location and at the same position of the above LEDs.
  • Luminescence each LED has a modulation frequency of 0 Hz, a wavelength of 675 nm, and a power of 1 mW.
  • the formula is mixed with red light and blue light, which can reduce the tingling sensation caused by pure blue light irradiation on the retinal visual area, and does not weaken the stimulating effect of blue light on the non-visual area of the retina.
  • the present invention also relates to an apparatus for implementing the above method.
  • the apparatus includes a registration unit 1, an identity verification unit 2, a parameter set selection unit 3, a parameter set adjustment unit 4, and a brain wave acquisition and processing unit 5.
  • the login unit 1 is configured to log in to the server on the application of the mobile terminal, so that the application is connected to the communication module on the illumination device, obtain identity information and configuration status of the illumination device, and forward the message to the a server;
  • the authentication unit 2 is configured to verify the user identity information of the login and the identity information of the illumination device after the server matches, and then call the user's illumination record and the latest detection data;
  • parameter set selection The unit 3 is configured to select a corresponding parameter set type in a preset plurality of types of parameter sets according to the detection data; and select a closest parameter set among the selected parameter set types according to the illumination record;
  • the set adjustment unit 4 is configured to send the obtained optical parameter set to the mobile terminal after performing the individual adjustment confirmation on the selected parameter set, and configured to the illumination device by using
  • the parameter set selection unit 3 further includes a special parameter set determination module 31 for detecting whether to store in a special parameter set for the user, and if so, to obtain the special parameter set and replace it with the previous parameter selection The parameter set; if not, the previously selected parameter set is still used.
  • the parameter set adjustment unit 4 further includes an adjustment module 41 and a transmission module 42; wherein the adjustment module 41 is configured to detect whether the user uploads a parameter value of the current brain wave setting component, and if so, according to the parameter value The corresponding parameters in the parameter set are adjusted, and the next step is performed; if not, the next step is directly executed; the sending module 42 is configured to send the obtained parameter set as a configuration parameter set to the mobile terminal.

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Abstract

本发明涉及一种配置调节生物节律光照装置发光参数的方法，包括如下步骤：登录服务器，取得所述光照装置的身份信息和配置状态，并将其转发到所述服务器；验证所述登录的使用者身份信息和所述光照装置的身份信息，相符后调出所述使用者的光照记录及最近的检测数据；选择最接近的一个参数集；对所述选择的参数集进行个体调整确认后，将得到的光参数集发送到所述移动终端，并配置到所述光照装置，所述光照装置使用该参数集驱动发光单元发光。本发明还涉及一种实现上述方法的装置。实施本发明的配置调节生物节律光照装置的发光参数的方法及装置，具有以下有益效果：可因人因症调节光照参数、适应性和效果较好、并可降低视觉损伤。

Description

配置调节生物节律光照装置发光参数的方法及装置 技术领域
本发明涉及医用设备领域，更具体地说，涉及一种配置调节生物节律光照装置的发光参数的方法及装置。
 背景技术
人体生物节律失调与诸多病症高度相关，如AD（老年痴呆症）、帕金森病、抑郁症、失眠症等，这些病症不仅给患者本人及其家属带来痛苦，也给造社会造成严重负担。由于造成人体生物节律失调的原因复杂、所引起的病症多样，所以尽管世界范围的医疗科研机构和制药厂一直在努力，但是迄今为止药物治疗生物节律失调及其所引起的大部分病症，仍然处于尴尬的境地。近些年年开始兴起的光遗传学（Opto-genetics）研究发现，向植入小鼠大脑组织中的光纤、甚至向小鼠的眼睛发射某些特质光信号，可以显著调整其体内业已失调的某些生物节律，从而使得与这些节律相关的某些疾病出现治愈的迹象。例如美国麻省理工学院Li-Huei Tsa等于2016年在《Nature》发表的一篇论文报告，分别向植入AD鼠大脑的光纤和AD鼠的眼睛发射具有某种特质的LED光照，每天1小时、持续一个月后，测量发现AD鼠原本紊乱的脑电γ波重现周期性节律，解刨发现小鼠大脑组织内部与AD症相关的Aβ蛋白、Tau蛋白等某些业界公认AD症的标志性指标已经恢复到正常水平。在现有技术中，所采用的技术形式有所不同，但是所基于的原理却大致相同，即使用光线刺激人眼视网膜可有效抑制人体褪黑激色素分泌、从而起到调整人体生物钟的作用，因此原理上讲，凡是采用这类技术的装置均有可能在某种程度上奏效。但是随着使用需求的提高、尤其是随着光遗传学等最新研究的发展，不难发现这类技术在取得成效的同时也存在以下显著不足：由于现有技术中的发光参数都是事先设定的几种模式，不能根据光照效果进行修改，也不能根据具体使用人员的不同情况进行修改，因此其适应性较差、效果不好、可能对使用者带来视觉上的损害。
 技术问题
技术解决方案
本发明要解决的技术问题在于，针对现有技术的上述适应性较差、效果不好、可能会带来一定的视觉损害的缺陷，提供一种适应性较好、效果较好、能够将视觉损害的可能性降低的配置调节生物节律光照装置的发光参数的方法及装置。
本发明解决其技术问题所采用的技术方案是：构造一种配置调节生物节律光照装置的发光参数的方法，包括如下步骤：
    A）在移动终端的应用程序上登录服务器，使得所述应用程序与光照装置上的通信模块连接，取得所述光照装置的身份信息和配置状态，并将其转发到所述服务器；
    B）所述服务器验证所述登录的使用者身份信息和所述光照装置的身份信息，相符后调出所述使用者的光照记录及最近的检测数据；
    C）依据所述检测数据，在预设的多种类型的参数集中选择一个相应的参数集类型；依据所述光照记录，在选择的参数集类型中选择最接近的一个参数集；
    D）对所述选择的参数集进行个体调整确认后，将得到的光参数集发送到所述移动终端，并通过所述光照装置的通信模块配置到所述光照装置，所述光照装置使用该参数集驱动发光单元发光。
更进一步地，所述步骤C）还包括如下步骤:
    C1）检测是否存储在针对该使用者的特别参数集，如有，取得该特别参数集并用其替代之前选择的参数集；如无，依旧使用之前选择的参数集。
更进一步地，所述步骤D）中进一步包括：
    D1）检测该用户是否上传当前的脑电波设定成分的参数值，如有，依据该参数值对所述参数集中的相应参数进行调整，并执行下一步骤；如无，则直接执行下一步骤；
    D2）将得到的参数集作为配置参数集发送到所述移动终端。
更进一步地，所述步骤D）中，还包括如下步骤：
    D3）检测该用户是否上传其它经过认证的身体状态检测装置检测获得的用户健康状况数据，如是，依据所述用户健康数据按照设定规则调节所述发光参数值；如无，退出本步骤；其中所述用户健康状态数据包括但是不限于可连续检测24小时脉搏、呼吸等状态的手环或者手表等上传的根据脉搏、呼吸等数据获得的睡眠时间、深睡眠时间和持续时长等数据；
在一次登录后执行上述步骤后，依照设定的时间，重复执行步骤D）。
更进一步地，还包括如下步骤：
    E）在所述光照装置发光一定时间间隔后，通过脑电波采集装置，对使用者的脑电波进行采集及处理，得到其中设定成分的参数并上传到所述服务器。
更进一步地，所述参数集中的参数包括：中心波长及其光谱成分、光强度、光谱功率密度、光强度的时间调制频率、光强度的时间调制占空比、发光射位置和/或光发射和结束时间；所述脑电波的设定成分的参数值，包括但是不限于所述脑电波中的β波或γ波对应的最大功率谱密度对应的频率值。
更进一步地，所述步骤D1）中的相应参数调整包括：将所述β波或γ波对应的最大功率谱密度对应的频率值与所述参数集中的光强度的时间调制频率相比较，如果有偏差则通过重新设定所述光强度的时间调制频率，使之接近，直到所述两个频率之差相等或者小于一个设定值。
更进一步地，所述步骤D3）中的设定规则包括：将通过外设测得的睡眠开始时间与用户设定的理想睡眠开始时间进行比较，如有偏差，则根据该偏差等值调整蓝光LED照射开始时间，将该开始时间通过弹出信息方式提醒用户，并获得用户认可，直到通过外设测得的睡眠开始时间等于用户设定的理想睡眠时间，或者小于用户认可的某个设定值；以及
将深睡眠持续时长和用户设定的时长进行比较，如果尚未达到，则根据预设的调整程序，适当调整光照装置的蓝光照射强度和／或照射持续时间，直到通过外设测得的深睡眠时长等于或者大于用户设定的时长。
本发明还涉及一种实现上述方法的装置，包括：
登录单元：用于在移动终端的应用程序上登录服务器，使得所述应用程序与光照装置上的通信模块连接，取得所述光照装置的身份信息和配置状态，并将其转发到所述服务器；
   身份验证单元：用于在所述服务器验证所述登录的使用者身份信息和所述光照装置的身份信息，相符后调出所述使用者的光照记录及最近的检测数据；
    参数集选择单元：用于依据所述检测数据，在预设的多种类型的参数集中选择一个相应的参数集类型；依据所述光照记录，在选择的参数集类型中选择最接近的一个参数集；
    参数集调整单元：用于对所述选择的参数集进行个体调整确认后，将得到的光参数集发送到所述移动终端，并通过所述光照装置的通信模块配置到所述光照装置，所述光照装置使用该参数集驱动发光单元发光。
更进一步地，所述参数集选择单元还包括:
   特别参数集判断模块：用于检测是否存储在针对该使用者的特别参数集，如有，取得该特别参数集并用其替代之前选择的参数集；如无，依旧使用之前选择的参数集；
所述参数集调整单元进一步包括：
    调节模块：用于检测该用户是否上传当前的脑电波设定成分的参数值，如有，依据该参数值对所述参数集中的相应参数进行调整，并执行下一步骤；如无，则直接执行下一步骤；
    发送模块：用于将得到的参数集作为配置参数集发送到所述移动终端；
还包括：
脑电波采集及处理单元：用于在所述光照装置发光后，通过脑电波采集装置，对使用者的脑电波不断进行采集及处理，不断得到其中设定成分的参数值并上传到所述服务器。
 有益效果
实施本发明的配置调节生物节律光照装置的发光参数的方法及装置，具有以下有益效果：由于使用应用程序登录，使得针对用户个体在注册是提供的信息和在照射过程中上传的配置信息对发光参数集中的参数进行优化成为可能，使得用户每次登陆后得到的光参数都可以是最适应其当前状态的光参数集；同时，脑电波的引入使得即使在照射过程中，也可以根据之前照射的效果进行光参数调节，进而使得其适应性较好、效果较好、能够将视觉损害的可能性降低。
 附图说明
图1是本发明配置调节生物节律光照装置的发光参数的方法及装置实施例中该方法的流程图；
图2是所述实施例中系统的结构示意图；
图3是所述实施例中装置的结构示意图。
 本发明的最佳实施方式
本发明的实施方式
下面将结合附图对本发明实施例作进一步说明。
如图1所示，在本发明的一种配置调节生物节律光照装置的发光参数的方法及装置实施例中，该配置调节生物节律光照装置的发光参数的方法，包括如下步骤：
步骤S11登录服务器：在本实施例中，以一个包括调节生物节律的光照装置的系统为例，说明该装置的发光参数的配置过程。该系统的大致构成请参见图3，其包括服务器、移动终端、光照装置和脑电波处理设备。服务器用于存储用户数据，包括用户注册资料和用户采用光照后的多种数据，例如，脑电波数据和检查测试时得到的数据；服务器通过网络与移动终端上运行的应用程序连接，接收该应用程序上传的数据进行相应的处理、存储，同时也发送数据到该应用程序；光照装置按照通过移动终端传输到其上的发光参数产生并输出光线束，对人体的设定部位（例如，瞳孔的非视觉区域）进行照射；脑电波处理设备接收被上述光线束照射的使用者的脑电波，并对其进行处理，得到其中的设定成分的参数值，将该参数值通过上述移动终端上传到上述服务器中。在这些操作中，身份的确定是非常重要的。例如，脑电波数据上传，服务器需要知道这些数据属于哪个使用者；而发光参数下发时，也需要知道这些数据是适用于那个使用者的。因此，在本步骤中，使用者在移动终端的应用程序上登录服务器，使得所述应用程序与光照装置上的通信模块连接，取得所述光照装置的身份信息和配置状态，并将其转发到所述服务器；值得一提的是，此处，身份信息可以包括使用者的身份信息，例如，在注册时使用的名称等；也可以包括光照装置的身份信息，例如，该光照装置的硬件识别码等；还可以包括用户信息和光照装置身份信息的绑定信息等等。
步骤S12验证身份信息，取得用户数据：在本步骤中，所述服务器验证所述登录的使用者身份信息和所述光照装置的身份信息，相符后调出所述使用者的光照记录及最近的检测数据；也就是说，在本步骤中，服务器可以经过多重身份信息的验证，最后确认该用户是合法的使用者，并在其数据库中查找到该用户以往的注册信息和采用光照射的历史数据，包括其在定期的、现场检测后得到的效果评价信息等等。
步骤S13选择参数集类型和参数集：在本步骤中，依据所述检测数据，在预设的多种类型的参数集中选择一个相应的参数集类型；依据所述光照记录，在选择的参数集类型中选择最接近的一个参数集；具体来讲，由于该光照装置本身的种类以及每种光照装置可以调节的生物节律的类别较多，每种类型的发光参数是不同的，因此，将其发光参数按照调节的生物节律类型分为多个类型，在每个类型中，又按照设定的情况，例如，轻重程度或某个指标的多少程度，将其分为多个参数集；每个参数集中包括其所在种类的光照装置调节所在类别的生物节律的所有参数，当该参数集传输到该光照装置时，该光照装置直接使用该参数集中的参数进行配置，就能够发出符合该参数集定义的光线束，照射使用的指定部位，通常是非视觉区域，实现安全、有效的生物节律的调节。
值得一提的是，在本步骤中，一些情况下，可能存在针对个体的特别参数集，例如，被用户认可的医生或专家针对该用户的检测结果提出的照射方案或建议，这种参数集当然是需要优先采用的。因此，一些情况下，执行上述步骤之后还可以检测是否存储在针对该使用者的特别参数集，如有，取得该特别参数集并用其替代之前选择的参数集；如无，依旧使用之前选择的参数集。
步骤S14对参数集进行个体调整后输出或直接将所述参数集输出到光照装置：虽然上述取得的参数集可以直接使用，也有一定的效果。但是，由于该参数集是针对一种指标的程度来确定的，其对于个体而言，还是存在其中的一些参数进行微调的余地的。这种微调可以使得该参数集对于个体的效果得到加强。因此，在本步骤中，对所述选择的参数集进行个体调整确认后，将得到的光参数集发送到所述移动终端，并通过所述光照装置的通信模块配置到所述光照装置，所述光照装置使用该参数集驱动发光单元发光。在一些情况下，也可以不进行个体参数微调，直接将上述步骤中得到的参数集发送到光照装置。这样的操作虽然节省了一些步骤，但是可能效果并不太好。但是在一些情况下，例如，个体资料缺失，之前没有相关的照射效果资料等等，也是可以接受的一种替代方案。
在本实施例中，上述步骤S14）可以按照设定的时间间隔重复执行，便于在光照过程中按照其光照的效果，随时进行参数调节，以期得到更好的光照效果。
如前所述，在本实施例中，系统包括了脑电波处理设备，该设备在开始光照之前或光照过程中，取得并处理使用者的脑电波，不断得到其中设定成分的参数值并通过移动终端上传到所述服务器。而根据上述取得脑电波中的设定成分的参数值，对该使用者当前使用的参数集中的相应参数进行调整，能够使得使用者的生物节律与光照达成某种类似“共振”的关系，进而得到更好的调节效果。因此，在本实施例中，也可以在光照过程中对参数集中的相关参数进行个体调节。
如图2所示，在光照过程中对选择的参数集进行个体调整时（包括开始执行和重复执行时），可以包括如下步骤：
步骤S21有处理后的脑电波数据输入否，如否，跳转到步骤S24；如有，执行下一步骤；在本步骤中，判断是否有脑电波数据通过上述移动终端输入。
步骤S22取得脑电波数据中的设定成分参数值：在本步骤中，有移动终端上传的数据中取出上述脑电波设定成分的参数值。
步骤S23调节选择的参数集中的相应参数是上述设定成分值适配：在本步骤中，依据上述得到的脑电波的设定成分的参数值，对参数集中的相应参数进行调整。例如，依据脑电波数据中β波或γ波的频率值，使得该参数集中的光强度的时间调制频率与所述接收到的β波或γ波的频率接近或相等。
步骤S24输出选择的参数集：在本步骤中，输出上述经过个体调整或没有经过个体调整的参数集。
值得一提的是，在本实施例中，所述参数集中的参数包括：中心波长及其光谱成分、光强度、光谱功率密度、光强度的时间调制频率、光强度的时间调制占空比、发光射位置和/或光发射和结束时间；所述脑电波的设定成分的参数值包括其中的β波或γ波的频率值；对应于所述脑电波中设定成分的相应参数包括光强度的时间调制频率。
在本实施例中，上述参数是可以按照光照过程中或光照后使用者的生物节律来进行调节的，这种调节可以是针对事先设定的参数集中部分参数的。例如，前述的在光照过程中按照使用者的脑电波的特性，当前的参数集进行调节。例如，在上述的依据脑电波中设定的成分的调节中，其相应参数调整包括：将所述β波或γ波对应的最大功率谱密度对应的频率值与所述参数集中的光强度的时间调制频率相比较，如果有偏差则通过重新设定所述光强度的时间调制频率，使之接近，多次重复上述步骤，使得二者的差值逐渐减小，直到所述两个频率之差相等或者小于一个设定值。
在本实施例中，在针对一种症状进行光照时，其进行调节的参数可能是不同的。例如，在一种情况下，针对失眠，其参数调节的步骤按照设定规则进行，而设定规则包括：将通过外设测得的睡眠开始时间与用户设定的理想睡眠开始时间进行比较，如有偏差，则根据该偏差等值调整蓝光LED照射开始时间，将该开始时间通过弹出信息方式提醒用户，并获得用户认可，直到通过外设测得的睡眠开始时间等于用户设定的理想睡眠时间，或者小于用户认可的某个设定值；此外，也可以将深睡眠持续时长和用户设定的时长进行比较，如果尚未达到，则根据预设的调整程序，适当调整光照装置的蓝光照射强度和／或照射持续时间，直到通过外设测得的深睡眠时长等于或者大于用户设定的时长。
总体上来看，在本实施例中，光照装置包括设计成适合佩戴在人脸上的眼镜形状的装置框架，装置框架上的控制模块、光调制模块、多个LED灯组、通信模块、环境光传感器、电源模块等。其中，所述控制模块包括核心处理器及简易输入按键，分别与光调制模块、通信模块、环境光传感器、电源模块直接连接，与多个LED灯组间接连接，起到实时调控整个装置的作用；所述光调制模块控制所述多个LED灯组输出的具体光参数；所述多个LED灯组被所述光调制模块调制后的信号驱动发出符合设定参数的光；所述通信模块提供连接通道，与智能设备APP（即移动终端上的应用程序）连接；所述环境光传感器将实时收集的装置背景光信息传入所述控制模块，辅助调节所述光调制模块；所述电源模块受所述控制模块调控，用于整个人体生物节律调节装置供电。
在本实施例中，上述装置框架采用全框眼镜形状。眼镜轮廓略大于现有市场使用的常规眼镜，不但支持用户在未佩戴眼镜情况下使用，而且支持用户在已佩戴眼镜情况下使用，不影响正常使用效果。所述装置框架设计满足不同用户的使用情况，扩大使用范围，提高装置实用性和有效性。所述LED灯组设置于所述装置框架的镜圈的相对上下位置，所述LED灯组可为一组或二组或三组或四组或五组或六组或七组或八组，所述LED灯组每组包括一个或二个或三个LED灯，所述LED灯组的发光体前端到达人眼虹膜的距离为12-16mm。
在一个较佳的例子中，所述LED灯组的发光体前端到达人眼虹膜的距离为14mm左右。可以有效的控制对人眼周边视网膜的刺激。由于多组LED灯组分别照不同区域，减少功率密度分布，降低光照损伤；多个LED灯组可实现多波长组合，增加剌激的范围，同时组合多色光可降低单色光造对视觉区刺激造成的不适。有效实现在不影响正常视觉的情况下光照到周边视网膜。提供一个基本均匀的照射，并可以允许一定范围的眼部运动，如眼睛睁大或者旋转等。在本实施例中，使得角膜表面有效光强范围为8-8000lux，从瞳孔入射的光功率范围8-800uw/cm。
所述多个LED灯组的各个LED管尖（即LED出光面）均倾斜一定角度指向瞳孔，避免直射黄斑区，同时保证有效照射周边视网膜的各个不同区域包括鼻区和侧区且不影响正常视觉。所述LED灯组中的各个LED为高指向性。一般为尖头环氧封装，或是带金属反射腔封装，或者外加聚光透镜，且不加散射剂，发光角为15度-20度，保证活动时瞳孔不脱离所述LED灯组发光覆盖范围，同时防止过多杂散光照射眼睛附近。可认为光斑在虹膜表面的直径和虹膜直径基本相等。
所述光调制模块采用光调制与光谱混频使所述LED灯组可输出不同时间调制频率不同波长不同强度的光，使用多组所述LED灯组可实现不同组合的光在瞳孔处形成复合光，所述光调制模块控制所述LED灯组输出的具体光参数包括时间频率、发光强度及占空比，调制效果包括波长组合、频率组合及强度组合，所述光调制模块控制所述LED灯组输出的具体光参数包括单组所述LED灯组的时间调制频率、波长调制、强度调制及占空比调制，所述光调制模块控制所述LED灯组输出的具体光参数包括多组LED灯组的深度调制、色温调制及功率调制，单组所述LED灯组的频率调制范围为0-80Hz、波长调制范围为450-670nm、强度调制范围为2-2000lux、占空比调制范围为0-100%，所述光调制模块可调制多组（例如，2-8组）所述LED灯组与背景光对比的深度调制、色温调制及功率调制，其深度调制范围为0-100%。总之，光调制模块11控制所述多个LED灯组输出的具体光参数，具体调制方式主要包括：时间频率、发光强度、占空比；最终调制效果表现为：波长组合、频率组合、强度组合。
所述光调制模块控制所述多组LED灯组输出的具体光参数，包括实现单组LED灯的时间调制频率、波长调制、强度调制、占空比调制和综合多组LED灯的深度调制、色温调制、功率调制。调制光均在人眼可接受范围内且满足了光生物学研究的常规需求，包括最新资料显示可能对AD患者（老年痴呆症患者）影响较大的固定频率40Hz的蓝光。
在本实施例中，上述所述智能设备或移动终端为智能手机，而且必须带有蓝牙通信模块，并保证有足够存储空间装载与运行所述手机APP。智能手机，其操作系统可包括常用的Windows、Android、苹果IOS等。APP为用户提供登录、注册、认证、评估等一系列常用语言界面，便于用户使用；具有Wi-Fi、4G等通用通信接口，以便与云端服务器进行通信。用户可借助于APP界面登记个人信息包括拟调理的病症信息、填写专业量表进行病症评估、与其他用户分享与交流使用体验等。
值得一体的是，所述光照节装置上具有一个机械开关，支持用户在不登陆云端服务器情况下，可以仅通过打开和关闭开关即可使用该人体生物节律调节装置，唯此时所用配方为上次登录时所下载数据；系统支持下次登录时上传上次使用情况的信息。
在本实施例中，上述一个参数集可以视为一种“光照配方”，其按照不同的适应症状分类，每类中又可以包括多个这样的参数集。
例如，在一种适应症状（例如，AD）的分类下可以包括四种参数集，如下
1：左右眼的鼻外侧共4个蓝光LED发光,每个LED的调制频率40Hz、波长463nm、占空比40%、功率2mW；
2：左右眼的鼻外侧仅上部共2个蓝光LED发光,每个LED的调制频率40Hz、波长463nm、占空比40%、功率2mW；
3：左右眼的鼻外侧4个蓝光LED发光,每个LED的调制频率40Hz、波长463nm、占空比40%、功率2mW；位于上述LED同一区位、同一位置的红光LED发光，每个LED的调制频率0Hz、波长675nm、功率1mW。该配方通过红光与蓝光混合，可减弱单纯蓝光照射对于视网膜视觉区造成的刺痛感，并不会减弱蓝光对于视网膜非视觉区的刺激作用；
4：左右眼的鼻外侧仅上部2个蓝光LED发光,每个LED的调制频率40Hz、波长463nm、占空比40%、功率2mW；位于上述LED同一区位、同一位置的共2个红光LED发光，每个LED的调制频率0Hz、波长675nm、功率1mW。该配方通过红光与蓝光混合，可减弱单纯蓝光照射对于视网膜视觉区造成的刺痛感，并不会减弱蓝光对于视网膜非视觉区的刺激作用。
一般情况下，系统会根据用户个人情况包括病情，通过优化算法向用户推荐合适的光照“配方”，并通过APP自动开启调节单元进行照射。治疗数据通过APP发送到云端服务器，包括开始时间和结束时间、配方等；同时所述人体生物节律调节装置会记录用户选择的光照“配方”。同时这些记录信息会保存在用户的智能设备和同步到所述云端服务器注册者的名下。
又如，另一种适应症状（例如，失眠）分类下的参数集也可以包括4种，如下：
1：左右眼的鼻外侧共4个蓝光LED发光,每个LED的调制频率0Hz、波长465nm、占空比40%、功率2mW；
2：左右眼的鼻外侧仅上部共2个蓝光LED发光,每个LED的调制频率0Hz、波长465nm、占空比40%、功率2mW；
3：左右眼的鼻外侧4个蓝光LED发光,每个LED的调制频率0Hz、波长465nm、占空比40%、功率2mW；位于上述LED同一区位、同一位置的红光LED发光，每个LED的调制频率0Hz、波长675nm、功率1mW。该配方通过红光与蓝光混合，可减弱单纯蓝光照射对于视网膜视觉区造成的刺痛感，并不会减弱蓝光对于视网膜非视觉区的刺激作用；
4：左右眼的鼻外侧仅上部2个蓝光LED发光,每个LED的调制频率0Hz、波长465nm、占空比40%、功率2mW；位于上述LED同一区位、同一位置的共2个红光LED发光，每个LED的调制频率0Hz、波长675nm、功率1mW。该配方通过红光与蓝光混合，可减弱单纯蓝光照射对于视网膜视觉区造成的刺痛感，并不会减弱蓝光对于视网膜非视觉区的刺激作用。
 
本发明还涉及一种实现上述方法的装置，如图4所示，该装置包括登录单元1、身份验证单元2、参数集选择单元3、参数集调整单元4和脑电波采集及处理单元5。其中，登录单元1用于在移动终端的应用程序上登录服务器，使得所述应用程序与光照装置上的通信模块连接，取得所述光照装置的身份信息和配置状态，并将其转发到所述服务器；身份验证单元2用于在所述服务器验证所述登录的使用者身份信息和所述光照装置的身份信息，相符后调出所述使用者的光照记录及最近的检测数据；参数集选择单元3用于依据所述检测数据，在预设的多种类型的参数集中选择一个相应的参数集类型；依据所述光照记录，在选择的参数集类型中选择最接近的一个参数集；参数集调整单元4用于对所述选择的参数集进行个体调整确认后，将得到的光参数集发送到所述移动终端，并通过所述光照装置的通信模块配置到所述光照装置，所述光照装置使用该参数集驱动发光单元发光；脑电波采集及处理单元5用于在所述光照装置发光后，通过脑电波采集装置，对使用者的脑电波不断进行采集及处理，不断得到其中设定成分的参数值并上传到所述服务器。
更进一步地，所述参数集选择单元3还包括特别参数集判断模块31，该模块用于检测是否存储在针对该使用者的特别参数集，如有，取得该特别参数集并用其替代之前选择的参数集；如无，依旧使用之前选择的参数集。所述参数集调整单元4进一步包括调节模块41和发送模块42；其中，调节模块41用于检测该用户是否上传当前的脑电波设定成分的参数值，如有，依据该参数值对所述参数集中的相应参数进行调整，并执行下一步骤；如无，则直接执行下一步骤；发送模块42用于将得到的参数集作为配置参数集发送到所述移动终端。
以上所述实施例仅表达了本发明的几种实施方式，其描述较为具体和详细，但并不能因此而理解为对本发明专利范围的限制。应当指出的是，对于本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干变形和改进，这些都属于本发明的保护范围。因此，本发明专利的保护范围应以所附权利要求为准。

Claims (10)

  1. 一种配置调节生物节律光照装置发光参数的方法，其特征在于，包括如下步骤：
        A）在移动终端的应用程序上登录服务器，使得所述应用程序与光照装置上的通信模块连接，取得所述光照装置的身份信息和配置状态，并将其转发到所述服务器；
        B）所述服务器验证所述登录的使用者身份信息和所述光照装置的身份信息，相符后调出所述使用者的光照记录及最近的检测数据；
        C）依据所述检测数据，在预设的多种类型的参数集中选择一个相应的参数集类型；依据所述光照记录，在选择的参数集类型中选择最接近的一个参数集；
        D）对所述选择的参数集进行个体调整确认后，将得到的光参数集发送到所述移动终端，并通过所述光照装置的通信模块配置到所述光照装置，所述光照装置使用该参数集驱动发光单元发光。
  2. 根据权利要求1所述的配置调节生物节律光照装置的发光参数的方法，其特征在于，所述步骤C）还包括如下步骤:
        C1）检测是否存储在针对该使用者的特别参数集，如有，取得该特别参数集并用其替代之前选择的参数集；如无，依旧使用之前选择的参数集。
  3. 根据权利要求2所述的配置调节生物节律光照装置的发光参数的方法，其特征在于，所述步骤D）中进一步包括：
        D1）检测该用户是否上传当前的脑电波设定成分的参数值，如有，依据该参数值对所述参数集中的相应参数进行调整，并执行下一步骤；如无，则直接执行下一步骤；
        D2）将得到的参数集作为配置参数集发送到所述移动终端。
  4. 根据权利要求3所述的配置调节生物节律光照装置的发光参数的方法，其特征在于，所述步骤D）中，还包括如下步骤：
        D3）检测该用户是否上传其它经过认证的身体状态检测装置检测获得的用户健康状况数据，如是，依据所述用户健康数据按照设定规则调节所述发光参数值；如无，退出本步骤；其中所述用户健康状态数据包括但是不限于可连续检测24小时脉搏、呼吸等状态的手环或者手表等上传的根据脉搏、呼吸等数据获得的睡眠时间、深睡眠时间和持续时长等数据；
    在一次登录后执行上述步骤后，依照设定的时间，重复执行步骤D）。
  5. 根据权利要求1-4所述的配置调节生物节律光照装置的发光参数的方法，其特征在于，还包括如下步骤：
        E）在所述光照装置发光一定时间间隔后，通过脑电波采集装置，对使用者的脑电波进行采集及处理，得到其中设定成分的参数并上传到所述服务器。
  6. 根据权利要求5所述的配置调节生物节律光照装置发光参数的方法，其特征在于，所述参数集中的参数包括：中心波长及其光谱成分、光强度、光谱功率密度、光强度的时间调制频率、光强度的时间调制占空比、发光射位置和/或光发射和结束时间；所述脑电波的设定成分的参数值，包括但是不限于所述脑电波中的β波或γ波对应的最大功率谱密度对应的频率值。
  7. 根据权利要求3所述的配置调节生物节律光照装置的发光参数的方法，其特征在于，所述步骤D1）中的相应参数调整包括：将所述β波或γ波对应的最大功率谱密度对应的频率值与所述参数集中的光强度的时间调制频率相比较，如果有偏差则通过重新设定所述光强度的时间调制频率，使之接近，直到所述两个频率之差相等或者小于一个设定值。
  8. 根据权利要求3所述的配置调节生物节律光照装置的发光参数的方法，其特征在于，所述步骤D3）中的设定规则包括：将通过外设测得的睡眠开始时间与用户设定的理想睡眠开始时间进行比较，如有偏差，则根据该偏差等值调整蓝光LED照射开始时间，将该开始时间通过弹出信息方式提醒用户，并获得用户认可，直到通过外设测得的睡眠开始时间等于用户设定的理想睡眠时间，或者小于用户认可的某个设定值；以及
    将深睡眠持续时长和用户设定的时长进行比较，如果尚未达到，则根据预设的调整程序，适当调整光照装置的蓝光照射强度和／或照射持续时间，直到通过外设测得的深睡眠时长等于或者大于用户设定的时长。
  9. 一种实现如权利要求1中所述的配置调节生物节律光照装置发光参数方法的装置，其特征在于，包括：
    登录单元：用于在移动终端的应用程序上登录服务器，使得所述应用程序与光照装置上的通信模块连接，取得所述光照装置的身份信息和配置状态，并将其转发到所述服务器；
       身份验证单元：用于在所述服务器验证所述登录的使用者身份信息和所述光照装置的身份信息，相符后调出所述使用者的光照记录及最近的检测数据；
        参数集选择单元：用于依据所述检测数据，在预设的多种类型的参数集中选择一个相应的参数集类型；依据所述光照记录，在选择的参数集类型中选择最接近的一个参数集；
        参数集调整单元：用于对所述选择的参数集进行个体调整确认后，将得到的光参数集发送到所述移动终端，并通过所述光照装置的通信模块配置到所述光照装置，所述光照装置使用该参数集驱动发光单元发光。
  10. 根据权利要求9所述的装置，其特征在于，所述参数集选择单元还包括:
       特别参数集判断模块：用于检测是否存储在针对该使用者的特别参数集，如有，取得该特别参数集并用其替代之前选择的参数集；如无，依旧使用之前选择的参数集；
    所述参数集调整单元进一步包括：
        调节模块：用于检测该用户是否上传当前的脑电波设定成分的参数值，如有，依据该参数值对所述参数集中的相应参数进行调整，并执行下一步骤；如无，则直接执行下一步骤；
        发送模块：用于将得到的参数集作为配置参数集发送到所述移动终端；
    还包括：
        脑电波采集及处理单元：用于在所述光照装置发光后，通过脑电波采集装置，对使用者的脑电波进行采集及处理，得到其中设定成分的参数值并上传到所述服务器。
     
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