WO2019144302A1 - 一种支架 - Google Patents

一种支架 Download PDF

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Publication number
WO2019144302A1
WO2019144302A1 PCT/CN2018/073904 CN2018073904W WO2019144302A1 WO 2019144302 A1 WO2019144302 A1 WO 2019144302A1 CN 2018073904 W CN2018073904 W CN 2018073904W WO 2019144302 A1 WO2019144302 A1 WO 2019144302A1
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WO
WIPO (PCT)
Prior art keywords
stent
base
inner core
bracket
stand according
Prior art date
Application number
PCT/CN2018/073904
Other languages
English (en)
French (fr)
Inventor
李波
张国伟
宿红刚
王健
徐保东
Original Assignee
北京形梦信息技术有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 北京形梦信息技术有限公司 filed Critical 北京形梦信息技术有限公司
Priority to CN201890000261.5U priority Critical patent/CN210494322U/zh
Priority to PCT/CN2018/073904 priority patent/WO2019144302A1/zh
Publication of WO2019144302A1 publication Critical patent/WO2019144302A1/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/32Joints for the hip
    • A61F2/36Femoral heads ; Femoral endoprostheses

Definitions

  • the present invention relates to a stent, and more particularly to a stent that can be combined with a vascular graft for the treatment of femoral head necrosis.
  • Femoral head necrosis also known as avascular necrosis of the femoral head
  • Femoral head necrosis is a common and refractory disease in the field of orthopedics. It is a kind of lesion that causes partial ischemia of the femoral head due to various reasons, which causes further ischemia, necrosis, trabecular bone fracture and collapse of the femoral head. If not treated effectively, about 80% of patients will have femoral head collapse within 1-4 years, secondary joint dysfunction, and eventually patients have to undergo artificial joint replacement, the high cost of artificial joint replacement to patients and society There is a huge economic burden, and because of the certain life span of artificial joints, the joint replacement of young and middle-aged patients often faces problems of joint loosening.
  • the present invention provides a bracket comprising: a bracket inner core including an inner core base portion and a middle partition portion, wherein the inner core of the bracket passes through the inner core base The section and the middle partition extend longitudinally with a tunnel.
  • the base portion includes a base end and a base end, and the outer surface of the base end and/or the base end is provided with a thread.
  • the base portion further includes a base end extension, the base end extension being located between the base end and the base end.
  • the diameter of the base end is larger than the septum, and the diameter of the base end is larger than the base end.
  • the bottom end surface of the base portion is provided with a recessed hole or a groove.
  • the bracket further comprises: a bracket shell comprising a porous portion and a threaded portion, the bracket inner core being insertable into the bracket shell and coupled thereto.
  • the threaded portion has a thread on the inner wall that is engageable with a thread on the head end of the base portion.
  • the bracket further comprises: a protective cover sleeve on the middle partition of the inner core of the bracket, the protective sleeve being degradable.
  • the stent housing and the septum are porous structures made in 3D printing.
  • the inner core of the bracket has a plurality of holes
  • the head end of the middle partition has a recess
  • the plurality of holes meet at the recess.
  • the stent can be combined with vascular grafting to repair the local biomechanical strength of the lesion after removal. Furthermore, the local microcirculation system is reconstructed to promote the regeneration and repair of bone tissue and to reconstruct local blood supply and bone mass.
  • Fig. 1 is a cross-sectional view showing a state of an embodiment of a stent of the present invention.
  • Fig. 2 is a cross-sectional view showing another state of the stent shown in Fig. 1.
  • Figure 3 is a perspective view of the inner core of the stent of the stent of Figure 1.
  • Figure 4 is a cross-sectional view of the stent core of the stent of Figure 3.
  • Figure 5 is a top plan view of one embodiment of the bottom of the stent of Figure 1.
  • Figure 6 is a top plan view of another embodiment of the bottom of the stent of Figure 1.
  • Figure 7 is a perspective view of another embodiment of the stent of the present invention.
  • Figure 8 is a cross-sectional view of the stent of Figure 7.
  • Figure 9 is a perspective view of an angle of the inner core of the stent of the stent of Figure 7.
  • Figure 10 is a perspective view of another angle of the stent core of the stent of Figure 7.
  • Figure 11 is a cross-sectional view of still another embodiment of the stent of the present invention.
  • Figure 12 is a cross-sectional view of still another embodiment of the stent of the present invention.
  • Figure 13 is a perspective view of still another embodiment of the stent of the present invention.
  • Bracket housing-1 porous portion-11; threaded portion-12; bracket inner core-2; base portion-21; intermediate partition portion-22; bore-23; groove-24; base portion end end -211; base portion Tail end -212; base end extension -213; protective sleeve-3.
  • Fig. 1 shows a cross-sectional view of the stent before assembly.
  • the bracket includes a bracket housing 1 and a bracket inner core 2 that can be inserted into the bracket housing 1 and combined with the bracket housing 1.
  • the left side of the figure is the head end, and the right side is the tail end, that is, the bracket shell 1 is located at the head end of the bracket relative to the bracket inner core 2, and correspondingly, the bracket inner core 2 is located at the bracket. Tail end.
  • the bracket housing 1 includes a porous portion 11 and a threaded portion 12, and the porous portion 11 may be a porous structure in which a whole gap is formed by 3D metal printing, the threaded portion 12 is solid, and the inner wall is provided with a thread.
  • the stent core 2 includes a base portion 21 and a middle partition portion 22.
  • the intermediate portion 22 is elongated.
  • the intermediate portion 22 is a solid or porous structure, and if it is a porous structure, it can be a porous structure in which the entire gap is made by 3D metal printing.
  • the outer surface of the head end 211 and/or the tail end 212 (see Fig. 3) of the base portion 21 is provided with a thread.
  • the externally threaded or roughened surface of the base bottom end 212 is used to increase friction with the bone during use so that the stent core 2 adheres more strongly to the bone.
  • the bottom end face of the base portion 21 is provided with a recess or recess 24 for connection to an external instrument.
  • Figures 5 - 6 show the shape of the bottom end face (described in detail later).
  • the diameter of the base end 211 is larger than the intermediate portion 22, and the diameter of the base end 212 is larger than the base end 211.
  • the outer side of the stent core 2 is provided with a tunnel 23 in the axial direction, and the tunnel 23 is used for implanting a blood vessel.
  • a blood vessel such as a large/small saphenous vein, a small arteriovenous bundle in an adjacent or other site, an artificial blood vessel or an artificial blood vessel in combination with an autologous blood vessel, etc.
  • the number and position of the tunnels 23 can be provided on the holder core 2 as needed.
  • the tunnel 23 can also be disposed inside the inner core 2 of the bracket. 3 and 4 clearly show the position and shape of the tunnel 23.
  • a smooth groove or recess (not shown) is opened at the head end of the intermediate portion 22 (at the circle of FIG. 3), and a plurality of holes 23 are formed in the holder core 2 At this time, a plurality of cells 23 meet at the grooves or depressions so that the implanted blood vessels can be smoothly folded back from one of the channels 23 of the septum 22 to the other of the cells 23 of the septum 22.
  • the head end of the stent core 2 (at the circle of FIG. 2) is concave, so that the blood vessel does not protrude from the surface of the stent core 2 when it is folded back or passed there. To protect blood vessels.
  • the bracket housing 1 can be combined with the threads on the outer surface of the base portion 21 of the bracket inner core 2 by its threaded portion 12 to achieve a combination of brackets.
  • the threads of the threaded portion 12 and the head end of the base portion 21 are screwed into each other to effect a combination of the brackets.
  • the position of the connection area of the bracket housing 1 and the bracket inner core 2 can be various.
  • Figure 2 shows a cross-sectional view of the assembled stent.
  • the stent can be implanted into the cavity formed by the avascular necrosis of the avascular necrosis of the femoral head, which plays a role in biomechanical support and promotes the growth of blood vessels and bone tissue.
  • the stent housing 1 and the stent core 2 can be prepared by 3D printing technology or by non-3D printing techniques (such as vapor deposition or sintering).
  • the stent can be processed into any other shape as needed.
  • the stent of the present invention is a porous titanium alloy stent, and the material of the stent can also be tantalum, titanium-niobium alloy, nickel-titanium alloy, pure titanium, cobalt alloy, calcium phosphate, hydroxyapatite, polylactic acid (PLA), lactic acid-glycolic acid. Copolymer (PLGA), polyacetal lactone (PCL), coral or bioceramics.
  • the bracket further includes a protective cover 3 which is degradable.
  • the degradable protective cover 3 can cover the front end surface of the stent core 2 to protect the vascular tissue of the implanted stent.
  • the bracket housing 1 Under the protection of the protective cover 3, the bracket housing 1 can be screwed into each other by the threads of the threaded portion 12 and the base end 211 of the bracket inner core 2, thereby realizing the combination of the brackets.
  • the protective cover 3 can be prepared from various degradable materials, and can be degraded after being implanted into the body, and does not hinder the growth of bone tissue and vascular tissue.
  • the protective cover 3 can cover the front end surface of the stent inner core 1 to protect the vascular tissue of the implanted stent.
  • the stent outer casing 1 can pass through the threaded portion 12 of the tail end and the base portion of the stent inner core 2.
  • the threads of the end 211 are screwed into each other to achieve a combination of brackets.
  • the blood vessel is implanted into the tunnel 23 to implant the stent, and after the components of the stent are combined, the graft blood vessel can be matched with the existing blood supply system (such as the lateral femoral artery and the arteriovenous system) around the hip joint to realize the vascularization of the stent.
  • the stent can be directly used after being implanted into the vascular bundle, and can also carry growth factors (such as BMP-2/VEGF, etc.) or stem cells in the porous structure to further enhance its ability to promote bone regeneration.
  • growth factors such as BMP-2/VEGF, etc.
  • Figures 7-10 show yet another embodiment of the stent of the present invention. It can be seen that it differs from the first embodiment in that the head end of the base portion 21 is divided into a base portion head end 211 and a base portion head end extension portion 213.
  • the base bottom end 211 has a thread and the base tip extension 213 is unthreaded. That is, the length of the base portion 21 can be extended as needed.
  • porous portion 11 of the stent casing 1 is a porous structure made of 3D printing.
  • the protective cover 3 is also shown.
  • Figure 11 shows a schematic view of a shape in which the length of the base portion 21 is longer than the stent shown in Figures 7-10.
  • Figures 12-13 show yet another embodiment of the stent of the present invention.
  • Figure 12 is a cross-sectional view of the stent
  • Figure 13 is a perspective view of the stent.
  • the porous portion 11 of the stent casing 1 is a porous structure made of 3D printing.
  • the septum 22 is also a porous structure made of 3D printing.

Abstract

一种支架,包括:支架内芯(2),支架内芯(2)包括内芯基底部(21)和中隔部(22),其中,在支架内芯(2)上,穿过内芯基底部(21)和中隔部(22)纵向延伸有孔道(23)。本发明可联合血管移植,修复病灶清除后局部的生物力学强度、重建局部的血运及骨质。

Description

一种支架 技术领域
本发明涉及一种支架,更具体地,涉及一种可联合血管移植治疗股骨头坏死的支架。
背景技术
股骨头坏死又称股骨头缺血性坏死,是骨科领域的常见且难治性疾病。它是由于多种原因导致的股骨头局部血运不良,从而引起骨细胞进一步缺血、坏死、骨小梁断裂、股骨头塌陷的一种病变。若未经有效治疗,约80%的患者会在1-4年内发生股骨头塌陷,继发关节功能障碍,最终患者不得不接受人工关节置换术,人工关节置换的高额费用给患者及社会带来了巨大的经济负担,而且由于人工关节有一定的寿命,中青年患者的关节置换后往往还面临着关节松动的问题,人工关节翻修手术难度及风险较高,人工关节翻修也将进一步加重患者的经济负担并显著降低患者的生活质量。最新研究表明股骨头坏死的发病率近年来呈逐年升高的趋势,而且其发病年龄呈现年轻化趋势。因此早期治疗股骨头坏死,以保留患者自身关节的治疗方法一直备受关注。
早期清除病灶,使用植入材料填充支撑缺损区域并促进骨再生是目前研究和临床治疗的热点之一。既往的材料研究中采取了干细胞治疗、自体骨/人工骨材料填充治疗及钽棒植入治疗等,然而均未取得令人满意的治疗效果。因为股骨头坏死的重要病因是其病变区域内血供受损或中断,这些材料虽然具有生物力学支撑或促进成骨的性能,但是难以重建病变区域的微循环系统,因此无法为注射的干细胞或新生的骨组织提供必须的营养及清除代谢废物,从而无法得到理想的治疗效果。
因此早期股骨头坏死的有效治疗方法需要同时解决以下三个问 题:病灶清除后骨缺损区域的生物力学支撑、局部微循环系统的重建以及促进骨组织的再生修复。
发明内容
针对现有技术中存在的问题,本发明提出一种支架,包括:支架内芯,所述支架内芯包括内芯基底部和中隔部,其中,在支架内芯上,穿过内芯基底部和中隔部纵向延伸有孔道。
可选地,所述基底部包括基底部头端和基底部尾端,基底部头端和/或基底部尾端的外表面设置有螺纹。
可选地,所述基底部还包括基底部头端延长部,基底部头端延长部位于基底部头端和基底部尾端之间。
可选地,基底部头端的直径比中隔部大,基底部尾端的直径比基底部头端大。
可选地,所述基底部的底端面设置有凹孔或凹槽。
可选地,所述的支架还包括:支架外壳,支架外壳包括多孔部和螺纹部,支架内芯能够插入支架外壳并与其结合。
可选地,所述螺纹部为在内壁上具有螺纹,能够与所述基底部头端上的螺纹相结合。
可选地,所述的支架还包括:保护套,保护套套在支架内芯的中隔部上,保护套为可降解的。
可选地,支架外壳和中隔部为3D打印制成的多孔结构。
可选地,所述支架内芯上具有多个孔道,中隔部头端具有凹陷,所述多个孔道在该凹陷处交汇。
本发明的支架的有益效果包括:
所述支架可联合血管移植,修复病灶清除后局部的生物力学强度。进而重建局部的微循环系统,促进骨组织的再生修复、重建局部的血运及骨质。
附图说明
图1为本发明的支架的一个实施方式的一种状态的剖视图。
图2为图1所示的支架的另一种状态的剖视图。
图3为图1所示支架的支架内芯的立体图。
图4为图3所示支架的支架内芯的剖视图。
图5为图1所示支架的底部的一个实施方式的俯视图。
图6为图1所示支架的底部的另一个实施方式的俯视图。
图7为本发明的支架的另一个实施方式的立体图。
图8为图7所示支架的剖视图。
图9为图7所示支架的支架内芯的一个角度的立体图。
图10为图7所示支架的支架内芯的另一个角度的立体图。
图11为本发明的支架的又一个实施方式的剖视图。
图12为本发明的支架的又一个实施方式的剖视图。
图13为本发明的支架的又一个实施方式的立体图。
附图标记
支架外壳-1;多孔部-11;螺纹部-12;支架内芯-2;基底部-21;中隔部-22;孔道-23;凹槽-24;基底部头端-211;基底部尾端-212;基底部头端延长部-213;保护套-3。
具体实施方式
下面参照附图描述本发明的实施方式,其中相同的部件用相同的附图标记表示。在不冲突的情况下,下述的实施例及实施例中的技术特征可以相互组合。
第一实施方式
在第一实施方式中,图1显示了支架组装前的剖视图。所述支架包括:支架外壳1和支架内芯2,支架内芯2能够插入支架外壳1中并与支架外壳1相结合。
需要说明的是,在本说明书中,图中左侧为头端,右侧为尾端,即支架外壳1相对于支架内芯2位于支架的头端,相应地,支架内芯 2位于支架的尾端。
支架外壳1包括多孔部11和螺纹部12,多孔部11可以为3D金属打印制成的整体空隙连通的多孔结构,螺纹部12为实心的,内壁上设置有螺纹。
如图3所示,支架内芯2包括基底部21和中隔部22。中隔部22为长条形。
中隔部22为实心的或者多孔结构,如果为多孔结构,则可以为3D金属打印制成的整体空隙连通的多孔结构。基底部21的头端211和/或尾端212(见图3)的外表面设置有螺纹。基底部尾端212的外螺纹或者粗糙表面用于在使用时与骨头加大摩擦力,从而支架内芯2更强的附着在骨头上。基底部21的底端面上设计有凹孔或凹槽24,用于与外部器械相连接。图5-图6显示了底端端面的形状(在后面详述)。优选地,基底部头端211的直径比中隔部22大,基底部尾端212的直径比基底部头端211大。
进一步,支架内芯2外侧沿轴向设置有孔道23,孔道23用于植入血管。通过将血管(如大/小隐静脉、邻近的或其他部位的小动静脉束、人工血管或者人工血管结合自体血管等等)移植入支架的孔道23内并延伸通过支架内芯2的基底部21和中隔部22,以实现血管植入支架内。孔道23的数量和位置可以根据需要设置在支架内芯2上。孔道23也可以设置在支架内芯2内部。图3和图4清楚地显示了孔道23的位置和形状。
可选地,如图3所示,在中隔部22的头端(图3的圆圈处)开有平滑的凹槽或凹陷(未示出),当支架内芯2上具有多个孔道23时,多个孔道23在该凹槽或凹陷处交汇使得植入的血管能够在该处从中隔部22的一个孔道23平滑地折返回中隔部22的另一个孔道23。
可选地,如图2所示,支架内芯2的头端(图2的圆圈处)为凹陷型,用于使得血管在此处折返或通过时不会凸出于支架内芯2表面,以保护血管。
支架外壳1可通过其螺纹部12与支架内芯2的基底部21外表面 上的螺纹相结合,实现支架的组合。优选地,螺纹部12与基底部21的头端的螺纹相互拧入,实现支架的组合。支架外壳1与支架内芯2的连接区的位置可有多种。
图2显示了装配后的支架的剖视图。组装后,该支架可植入股骨头缺血性坏死髓芯减压病灶清除后形成的空腔内,起到生物力学支撑和促进血管及骨组织长入的作用。
另外,支架外壳1及支架内芯2可通过3D打印技术制备,也可通过非3D打印技术制备(如气相沉积法或烧结法等等)。所述支架可根据需要加工成其他任意形体。本发明的支架为多孔钛合金支架,支架的材料也可为钽、钛钽合金、镍钛合金、纯钛、钴合金、磷酸钙、羟基磷灰石、聚乳酸(PLA)、乳酸-羟基乙酸共聚物(PLGA)、聚乙酸内脂(PCL)、珊瑚或生物陶瓷等材料。
参照图1和图2,优选地,所述支架还包括保护套3,保护套3为可降解的。可降解的保护套3可覆盖在支架内芯2的前端表面,保护植入支架的血管组织。在保护套3的保护下,支架外壳1可通过螺纹部12与支架内芯2的基底部头端211的螺纹相互拧入,实现支架的组合。保护套3可由各种可降解材料制备而成,植入体内后可实现降解,不妨碍骨组织及血管组织的长入。
保护套3可覆盖在支架内芯1的前端表面,保护植入支架的血管组织,在保护套3的保护下,支架外壳1可通过其尾端的螺纹部12与支架内芯2的基底部头端211的螺纹相互拧入,实现支架的组合。血管植入孔道23从而植入支架,并将支架各部件组合后,可将移植血管与髋关节周围现存的血供系统(如旋股外侧动静脉系统等)吻合,实现支架的血管化,以促进支架及病变区域内的血管生长,实现病变区域微循环系统的重建,为新生骨组织提供所需的干细胞、氧气、营养物质、生长因子及清除局部的代谢废物。该支架植入血管束后可直接使用,也可在多孔结构内部载生长因子(如BMP-2/VEGF等)或干细胞等从而进一步加强其促进骨再生的能力。
第二实施方式
图7-10显示了本发明的支架的又一个实施方式。可以看出,其与第一实施方式的区别在于,基底部21的头端分为基底部头端211和基底部头端延长部213。基底部头端211具有螺纹,基底部头端延长部213无螺纹。也就是说,基底部21的长度根据需要可以延长。
另外,支架外壳1的多孔部11为3D打印制成的多孔结构。图中还显示了保护套3。
图11显示了比图7-10所示的支架,基底部21的长度更长的一种形状的示意图。
第三实施方式
图12-13显示了本发明的支架的又一个实施方式。图12为支架的剖面图,图13为支架的立体图。
相比于第二实施方式,在本实施方式中,除了支架外壳1的多孔部11为3D打印制成的多孔结构。中隔部22也为3D打印制成的多孔结构。
以上所述的实施例,只是本发明较优选的具体实施方式,本领域的技术人员在本发明技术方案范围内进行的通常变化和替换都应包含在本发明的保护范围内。

Claims (10)

  1. 一种支架,其特征在于,包括:
    支架内芯(2),所述支架内芯(2)包括内芯基底部(21)和中隔部(22),其中,在支架内芯(2)上,穿过内芯基底部(21)和中隔部(22)纵向延伸有孔道(23)。
  2. 根据权利要求1所述的支架,其特征在于,
    所述基底部(21)包括基底部头端(211)和基底部尾端(212),基底部头端(211)和/或基底部尾端(212)的外表面设置有螺纹。
  3. 根据权利要求2所述的支架,其特征在于,
    所述基底部(21)还包括基底部头端延长部(213),基底部头端延长部(213)位于基底部头端(211)和基底部尾端(212)之间。
  4. 根据权利要求2所述的支架,其特征在于,
    基底部头端(211)的直径比中隔部(22)大,基底部尾端(212)的直径比基底部头端(211)大。
  5. 根据权利要求1所述的支架,其特征在于,
    所述基底部(21)的底端面设置有凹孔或凹槽(24)。
  6. 根据权利要求2所述的支架,其特征在于,还包括:
    支架外壳(1),支架外壳(1)包括多孔部(11)和螺纹部(12),支架内芯(2)能够插入支架外壳(1)并与其结合。
  7. 根据权利要求6所述的支架,其特征在于,
    所述螺纹部(12)为在内壁上具有螺纹,能够与所述基底部头端(211)上的螺纹相结合。
  8. 根据权利要求1所述的支架,其特征在于,还包括:
    保护套(3),保护套(3)套在支架内芯(2)的中隔部(22)上,保护套(3)为可降解的。
  9. 根据权利要求6所述的支架,其特征在于,
    支架外壳(1)和中隔部(22)为3D打印制成的多孔结构。
  10. 根据权利要求1所述的支架,其特征在于,
    所述支架内芯(2)上具有多个孔道(23),中隔部(22)头端具有凹陷,所述多个孔道(23)在该凹陷处交汇。
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5584836A (en) * 1994-04-07 1996-12-17 Smith & Nephew Richards, Inc. Cannulated medical suture anchor
CN102470035A (zh) * 2009-06-30 2012-05-23 捷迈公司 多孔医疗装置中的螺纹布置
CN106798600A (zh) * 2017-01-23 2017-06-06 北京形梦信息技术有限公司 一种组合支架
CN106798601A (zh) * 2017-01-23 2017-06-06 北京形梦信息技术有限公司 一种支架

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5584836A (en) * 1994-04-07 1996-12-17 Smith & Nephew Richards, Inc. Cannulated medical suture anchor
CN102470035A (zh) * 2009-06-30 2012-05-23 捷迈公司 多孔医疗装置中的螺纹布置
CN106798600A (zh) * 2017-01-23 2017-06-06 北京形梦信息技术有限公司 一种组合支架
CN106798601A (zh) * 2017-01-23 2017-06-06 北京形梦信息技术有限公司 一种支架

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