WO2019111568A1 - Light ultrasound measurement device, method, program, and storage medium - Google Patents

Light ultrasound measurement device, method, program, and storage medium Download PDF

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Publication number
WO2019111568A1
WO2019111568A1 PCT/JP2018/039411 JP2018039411W WO2019111568A1 WO 2019111568 A1 WO2019111568 A1 WO 2019111568A1 JP 2018039411 W JP2018039411 W JP 2018039411W WO 2019111568 A1 WO2019111568 A1 WO 2019111568A1
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WO
WIPO (PCT)
Prior art keywords
pulse
output
ultrasonic
light
optical
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PCT/JP2018/039411
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French (fr)
Japanese (ja)
Inventor
泰一郎 伊田
Original Assignee
株式会社アドバンテスト
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Application filed by 株式会社アドバンテスト filed Critical 株式会社アドバンテスト
Priority to DE112018006278.3T priority Critical patent/DE112018006278T5/en
Priority to CN201880076037.9A priority patent/CN111386082A/en
Publication of WO2019111568A1 publication Critical patent/WO2019111568A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5261Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from different diagnostic modalities, e.g. ultrasound and X-ray
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves

Definitions

  • the present invention relates to the measurement of photoacoustic waves and ultrasound.
  • Patent Documents 1 and 2 disclose a photoacoustic measurement device having a plurality of light sources.
  • Non-Patent Document 1 discloses AR-PAM, which is a type of photoacoustic measurement device.
  • Patent Document 3 discloses a measurement apparatus that measures an object using an illumination light generation unit and an ultrasonic wave generation unit one by one.
  • this invention makes it a subject to measure using an ultrasonic wave generation part and several pulse light sources.
  • An optical ultrasonic measurement device includes an ultrasonic pulse output unit that outputs an ultrasonic pulse, a plurality of pulsed light output units that output pulsed light having different wavelengths, the ultrasonic pulse, and a plurality of the pulsed light.
  • a pulse output time point control unit for controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output, so that the time when each of the ultrasonic waves is output does not overlap with each other; It comprises so that it may comprise a measurement part which measures the measurement object based on a reflected wave and a photoacoustic wave generated in the measurement object by the pulse light.
  • the ultrasonic pulse output unit outputs an ultrasonic pulse.
  • the plurality of pulsed light output units output pulsed light having different wavelengths.
  • the pulse output time point control unit controls the time point when each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights is output does not overlap with each other. Control.
  • a measurement unit measures the measurement object based on a reflected wave in which the ultrasonic pulse is reflected on the measurement object and a photoacoustic wave generated on the measurement object by the pulse light.
  • the trigger signal includes an ultrasonic pulse trigger signal and a plurality of pulse light trigger signals, and the ultrasonic pulse trigger signal generates the ultrasonic pulse.
  • each of the pulse light trigger signals may be supplied to each of the pulse light output units.
  • the pulse output time point control unit has a trigger signal delay unit that delays one of the trigger signals into another one of the trigger signals. It is also good.
  • an output synchronization trigger signal that is output in synchronization with a point in time when one of the pulse light output parts having the pulse output time point control part outputs the pulse light is delayed
  • An output synchronization trigger signal delay unit may be provided as one certain trigger signal.
  • the pulse output time point control unit may include an electric pulse delay unit that delays an electric pulse obtained by photoelectrically converting the pulse light to generate one certain trigger signal. You may
  • one of the pulsed light output units receives the pulsed light output from another one of the pulsed light output units, converts the wavelength, and outputs the converted light.
  • an optical switch may be provided which can switch which one of the pulse light output part and the measurement object the output of another one of the pulse light output parts is to be provided.
  • the optical ultrasonic measurement device includes a moving unit that receives a movement control pulse and moves a position at which the ultrasonic pulse and the pulse light are given to the measurement target, and the pulse output time point control unit
  • Each of the movement control pulse, the ultrasonic pulse, and the plurality of pulsed lights is such that the time during which each of the movement control pulse, the ultrasonic pulse, and the plurality of pulsed lights is output does not overlap with each other.
  • the point in time of output may be controlled.
  • each of the other ultrasonic pulse and the plurality of pulse lights may be output after the falling of the movement control pulse.
  • the present invention is an optical ultrasonic measurement method by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths, A pulse output time point control step of controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights is output does not overlap each other; A measuring method of an optical ultrasonic wave, comprising: a measuring step of measuring the object to be measured based on a reflected wave in which the ultrasonic pulse is reflected on the object to be measured and a photoacoustic wave generated on the object to be measured by the pulse light.
  • the present invention causes a computer to execute an optical ultrasonic measurement process by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths.
  • the optical ultrasonic measurement process is configured to prevent the ultrasonic pulse and the plurality of pulsed lights from being output for a period of time that the ultrasonic pulse and the plurality of pulsed lights do not overlap each other.
  • a pulse output time point control step of controlling a time point at which each of the plurality of pulses is output, a reflected wave in which the ultrasonic pulse is reflected at the measurement object, and a photoacoustic wave generated in the measurement object by the pulse light It is a program provided with the measurement process to measure.
  • the present invention causes a computer to execute an optical ultrasonic measurement process by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths.
  • a computer readable recording medium having recorded thereon a program for performing the optical ultrasonic measurement process so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights is output do not overlap each other
  • a pulse output time point control step of controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output, and generation of the ultrasonic pulse in the measurement target by a reflected wave reflected from the measurement target and the pulse light
  • 5 is a timing chart of trigger signals T1, T2 and T3 according to the first embodiment. It is a timing chart of a plurality of pulse lights P1 and P2 concerning a first embodiment, and an ultrasonic pulse P3.
  • It is a functional block diagram which shows the structure of the pulse output time point control part 20 in the optical ultrasonic measurement apparatus 1 concerning 2nd embodiment. It is a functional block diagram which shows the structure of the pulse output time point control part 20 in the optical ultrasonic measurement apparatus 1 concerning the modification of 2nd embodiment.
  • FIG. 1 is a functional block diagram showing a configuration of an optical ultrasonic measurement apparatus 1 according to a first embodiment of the present invention.
  • the optical ultrasonic measurement device 1 is for measuring a measurement target 2 (for example, a human body but is not limited thereto), and the pulse output unit 10 and the pulse output time point control unit 20 , Pulse light output units 30a and 30b, an ultrasonic pulse output unit 32, and a measurement unit 40.
  • a measurement target 2 for example, a human body but is not limited thereto
  • the pulse output unit 10 and the pulse output time point control unit 20 Pulse light output units 30a and 30b, an ultrasonic pulse output unit 32, and a measurement unit 40.
  • the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1).
  • the plurality of pulse light output units 30a and 30b output pulse lights P1 and P2 having different wavelengths. Although two pulse light output units 30 a and 30 b are provided in FIG. 1, three or more pulse light output units may be provided.
  • the ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
  • each of the pulse light trigger signals T1 and T2 is given to each of the pulse light output units 30a and 30b in order to generate the pulse lights P1 and P2.
  • the pulse light output unit 30 a generates the pulse light P 1 in synchronization with the pulse light trigger signal T 1 and applies the pulse light P 1 to the measurement target 2.
  • the pulse light output unit 30 b generates the pulse light P 2 in synchronization with the pulse light trigger signal T 2 and applies the pulse light P 2 to the measurement target 2.
  • An ultrasonic pulse trigger signal T3 is applied to the ultrasonic pulse output unit 32 to generate an ultrasonic pulse P3.
  • the ultrasonic pulse output unit 32 generates an ultrasonic pulse P3 in synchronization with the ultrasonic pulse trigger signal T3, and applies the ultrasonic pulse P3 to the measurement target 2.
  • the ultrasonic pulse trigger signal T3 and the plurality of pulse light trigger signals T1 and T2 are referred to as trigger signals.
  • the measurement unit 40 measures the measurement object 2 based on the reflected wave US in which the ultrasonic pulse is reflected at the measurement object 2 and the photoacoustic waves AW1 and AW2 generated in the measurement object 2 by the pulse lights P1 and P2.
  • AR-PAM as a structure for irradiating pulsed light P1 and P2 to measurement object 2, and receiving photoacoustic wave AW1 and AW2 in measurement part 40, for example, it is limited to AR-PAM It is not a thing.
  • the pulse output time point control unit 20 controls each of the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 so that the time during which each of the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 is output does not overlap with each other. Control the output time point (see FIG. 4).
  • FIG. 2 is a functional block diagram showing the configuration of the pulse output point control unit 20 according to the first embodiment.
  • the pulse output time point control unit 20 has delay units (trigger signal delay units) 20a and 20b.
  • the pulse output time point control unit 20 receives an electric pulse (same as the pulse light trigger signal T1) from the pulse output unit 10, outputs it as it is, and supplies it to the pulse light output unit 30a.
  • the delay unit (trigger signal delay unit) 20a delays a certain trigger signal T1 and supplies it as a single other trigger signal T2 to the pulse light output unit 30b and the delay unit 20b.
  • the delay unit (trigger signal delay unit) 20b delays a certain trigger signal T2 and supplies the delayed signal to the ultrasonic pulse output unit 32 as another trigger signal T3.
  • FIG. 3 is a timing chart of trigger signals T1, T2 and T3 according to the first embodiment.
  • the trigger signal T1 is delayed to become a trigger signal T2, and the trigger signal T2 is delayed to become a trigger signal T3.
  • the time during which the trigger signals T1, T2, and T3 are output (the time when it is High) does not overlap.
  • FIG. 4 is a timing chart of a plurality of pulse lights P1 and P2 and an ultrasonic pulse P3 according to the first embodiment.
  • a plurality of pulse lights P1 and P2 and an ultrasonic pulse P3 are output in synchronization with the trigger signals T1, T2 and T3.
  • the rise of the pulsed light P2 is delayed by ⁇ t1 from the rise of the pulsed light P1.
  • ⁇ t1 is larger than the pulse width W1 of the pulsed light P1.
  • the rise of the ultrasonic pulse P3 is delayed by ⁇ t2 from the rise of the pulsed light P2.
  • ⁇ t2 is larger than the pulse width W2 of the pulsed light P2.
  • the pulse light P2 is output after the pulse light P1
  • the ultrasonic pulse P3 is output after the pulse light P2.
  • it does not necessarily have to be output in the order of the pulse lights P1 and P2 and the ultrasonic pulse P3, and the order of the output is arbitrary.
  • the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1).
  • the electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
  • the pulse light trigger signal T1 is delayed by the delay unit 20a and given to the pulse light output unit 30b as a pulse light trigger signal T2.
  • the pulse light trigger signal T2 is delayed by the delay unit 20b and given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3.
  • the pulsed light output units 30a and 30b respectively output pulsed lights P1 and P2 having different wavelengths.
  • the ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
  • the pulse lights P1 and P2 and the ultrasonic pulse P3 are given to the measurement target 2.
  • the pulsed light P1 is given to the measurement target 2 to generate the photoacoustic wave AW1.
  • the pulsed light P2 is given to the object 2 to generate the photoacoustic wave AW2.
  • the ultrasonic pulse P3 is given to the measurement object 2, it is reflected. This reflected wave is the reflected wave US.
  • the measurement target 2 is measured by the measurement unit 40 based on the reflected wave US and the photoacoustic waves AW1 and AW2.
  • the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
  • the optical ultrasonic measurement apparatus 1 according to the second embodiment is an output synchronization in which one pulse light output unit 30a (30b) outputs the pulse light P1 (P2) in synchronization with the output time.
  • the point that the trigger signal T1out (T2out) is delayed to form one certain trigger signal T2 (T3) is different from the optical ultrasonic measurement device 1 according to the first embodiment.
  • FIG. 5 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the second embodiment. Note that among the constituent elements of the optical ultrasonic measurement device 1 according to the second embodiment, the same parts as those in the first embodiment are given the same reference numerals, and descriptions thereof will be omitted.
  • the measurement target 2, the pulse output unit 10, the ultrasonic pulse output unit 32, and the measurement unit 40 are the same as in the first embodiment, and thus the description thereof is omitted.
  • the pulse light output units 30a and 30b according to the second embodiment are the same as the first embodiment, but are different from the first embodiment in that the output synchronization trigger signals T1out and T2out are output.
  • the pulsed light output unit 30a outputs the output synchronization trigger signal T1out in synchronization with the time when the pulsed light P1 is output.
  • the pulsed light output unit 30b according to the second embodiment outputs the output synchronization trigger signal T2out in synchronization with the time when the pulsed light P2 is output.
  • the pulse output time point control unit 20 is the same as the first embodiment, but includes delay units (output synchronization trigger signal delay units) 20c and 20d.
  • the delay unit (output synchronization trigger signal delay unit) 20c delays the output synchronization trigger signal T1out into a trigger signal T2.
  • the delay unit (output synchronization trigger signal delay unit) 20d delays the output synchronization trigger signal T2out to a trigger signal T3.
  • the timing chart of the trigger signals T1, T2 and T3 is the same as in the first embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the first embodiment. Since there is (see FIG. 4), the description is omitted.
  • the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1).
  • the electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
  • the pulsed light output unit 30a outputs pulsed light P1. Furthermore, the pulse light output unit 30a outputs the output synchronization trigger signal T1out in synchronization with the time point when the pulse light P1 is output.
  • the output synchronization trigger signal T1out is delayed by the delay unit 20c and given to the pulse light output unit 30b as the pulse light trigger signal T2.
  • the pulsed light output unit 30b outputs pulsed light P2. Furthermore, the pulse light output unit 30b outputs the output synchronization trigger signal T2out in synchronization with the time when the pulse light P2 is output.
  • the output synchronization trigger signal T2out is delayed by the delay unit 20d and given to the ultrasonic pulse output unit 32 as the ultrasonic pulse trigger signal T3.
  • the ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
  • the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
  • both the pulse light output unit 30a and the pulse light output unit 30b output an output synchronization trigger signal.
  • FIG. 6 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the modification of the second embodiment.
  • the pulse output time point control unit 20 includes delay units 20c and 20e.
  • the delay unit 20c is similar to that of the second embodiment.
  • the delay unit (output synchronization trigger signal delay unit) 20e delays the output synchronization trigger signal T1out to a certain trigger signal T3.
  • the timing chart of the trigger signals T1, T2 and T3 is the same as in the second embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the second embodiment. Since there is (see FIG. 4), the description is omitted.
  • the optical ultrasonic measurement device 1 according to the third embodiment delays an electric pulse obtained by photoelectrically converting the pulse light P1 (P2) into one trigger signal T2 (T3). This is different from the optical ultrasonic measurement device 1 according to the first embodiment.
  • FIG. 7 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the third embodiment. Note that among the constituent elements of the optical ultrasonic measurement device 1 according to the third embodiment, the same parts as those in the first embodiment are given the same reference numerals, and descriptions thereof will be omitted.
  • the measurement target 2, the pulse output unit 10, the pulse light output units 30a and 30b, the ultrasonic pulse output unit 32, and the measurement unit 40 are the same as those in the first embodiment, and thus the description thereof is omitted.
  • the optical ultrasonic measurement device 1 includes the photodiodes PD1 and PD2.
  • the photodiode PD1 outputs an electrical pulse obtained by photoelectrically converting the pulse light P1.
  • the photodiode PD2 outputs an electrical pulse obtained by photoelectrically converting the pulse light P2.
  • the photodiodes PD1 and PD2 can be used instead.
  • the pulse output time point control unit 20 is the same as the first embodiment, but includes delay units (electric pulse delay units) 20f and 20g.
  • the delay unit (electric pulse delay unit) 20f delays the output of the photodiode PD1 to generate a trigger signal T2.
  • the delay unit (electric pulse delay unit) 20g delays the output of the photodiode PD2 to generate a trigger signal T3.
  • the timing chart of the trigger signals T1, T2 and T3 is the same as in the first embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the first embodiment. Since there is (see FIG. 4), the description is omitted.
  • the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1).
  • the electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
  • the pulsed light output unit 30a outputs pulsed light P1.
  • the pulse light P1 is photoelectrically converted by the photodiode PD1 into an electric pulse, delayed by the delay unit 20f, and given to the pulse light output unit 30b as a pulse light trigger signal T2.
  • the pulsed light output unit 30b outputs pulsed light P2.
  • the pulse light P2 is photoelectrically converted by the photodiode PD2, becomes an electric pulse, is delayed by the delay unit 20g, and is given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3.
  • the ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
  • the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
  • the optical ultrasonic measurement device 1 uses the optical switch 34 to switch the output of the pulse lights P1 and P2 to the measurement target 2 in the first embodiment. This differs from the optical ultrasonic measurement device 1.
  • FIG. 8 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the fourth embodiment.
  • the same parts as those of the first embodiment are denoted by the same reference numerals, and the description thereof will be omitted.
  • the measurement target 2, the pulse output unit 10, the pulse output time point control unit 20, the pulse light output unit 30a, the ultrasonic pulse output unit 32, and the measurement unit 40 are the same as those in the first embodiment, and the description is omitted.
  • the optical ultrasonic measurement device 1 includes a pulse light output unit 30 d and an optical switch 34.
  • the trigger signal T2 output from the delay unit 20a of the pulse output timing control unit 20 according to the fourth embodiment is supplied to the optical switch 34.
  • the pulsed light output unit 30d receives the pulsed light P1 output from the pulsed light output unit 30a, converts the wavelength, and outputs it. This output is the pulsed light P2.
  • the optical switch 34 can switch which of the pulsed light output unit 30 d and the measurement target 2 the output P 1 of the pulsed light output unit 30 a is to be provided. This switching is performed in synchronization with the time when the optical switch 34 receives the trigger signal T2.
  • the optical switch 34 Before receiving the trigger signal T2 that has become High, the optical switch 34 applies the output P1 of the pulsed light output unit 30a to the measurement target 2. After receiving the trigger signal T2 that has become High, the optical switch 34 applies the output P1 of the pulsed light output unit 30a to the pulsed light output unit 30d.
  • the timing chart of the trigger signals T1, T2 and T3 is the same as in the first embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the first embodiment. Since there is (see FIG. 4), the description is omitted.
  • the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1).
  • the electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
  • the pulsed light output unit 30a outputs pulsed light P1.
  • the pulsed light P1 is given to the measurement target 2 via the optical switch 34.
  • the pulse light trigger signal T1 is delayed by the delay unit 20a and given to the optical switch 34 as the pulse light trigger signal T2.
  • the optical switch 34 switches the output destination of the pulsed light P1 to the pulsed light output unit 30d.
  • the pulse light P2 is output from the pulse light output unit 30d.
  • the pulse light trigger signal T2 is delayed by the delay unit 20b and given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3.
  • the ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
  • the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
  • the optical ultrasonic measurement device 1 according to the fifth embodiment is different from the optical ultrasonic measurement device 1 according to the first embodiment in that a movement unit 50 is provided.
  • FIG. 9 is a functional block diagram showing the configuration of the optical ultrasonic measurement device 1 according to the fifth embodiment.
  • the optical ultrasonic measurement apparatus 1 includes a pulse output unit 10, a pulse output time point control unit 20, pulse light output units 30a and 30b, an ultrasonic pulse output unit 32, a measurement unit 40, and a moving unit 50.
  • a pulse output unit 10 a pulse output time point control unit 20
  • pulse light output units 30a and 30b pulse light output units 30a and 30b
  • an ultrasonic pulse output unit 32 pulse light output units 30a and 30b
  • a measurement unit 40 and a moving unit 50.
  • the components other than the moving unit 50 are the same as in the first embodiment, and the same reference numerals are given and the description is omitted.
  • the moving unit 50 receives the movement control pulse P4, and moves the position at which the ultrasonic pulse P3 and the pulse lights P1 and P2 are given to the measurement target 2.
  • the pulse output time point control unit 20 controls the movement control pulse P4, the ultrasonic pulse P3, and the movement pulse P4 so that the time during which each of the movement pulse P4, the ultrasonic pulse P3 and the plural pulse lights P1 and P2 is output does not overlap. The point in time when each of the plurality of pulsed lights P1 and P2 is output is controlled.
  • FIG. 10 is a functional block diagram showing the configuration of the pulse output time point control unit 20 according to the fifth embodiment.
  • the pulse output timing control unit 20 according to the fifth embodiment has delay units 20a, 20b, and 20k.
  • the delay units 20a and 20b are the same as in the first embodiment, and the description will be omitted.
  • the delay unit 20k delays the trigger signal T3 to generate a movement control pulse P4.
  • FIG. 11 is a timing chart of a plurality of pulse lights P1 and P2, an ultrasonic pulse P3 and photoacoustic waves AW1 and AW2 and a reflected wave US according to the fifth embodiment.
  • the times at which each of the movement control pulse P4, the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 is output do not overlap each other. Moreover, after the photoacoustic waves AW1 and AW2 and the reflected wave US are output, the movement control pulse P4 is output.
  • the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1).
  • the electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
  • the pulse light trigger signal T1 is delayed by the delay unit 20a and given to the pulse light output unit 30b as a pulse light trigger signal T2.
  • the pulse light trigger signal T2 is delayed by the delay unit 20b and given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3.
  • the pulsed light output units 30a and 30b respectively output pulsed lights P1 and P2 having different wavelengths.
  • the ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
  • the pulse lights P1 and P2 and the ultrasonic pulse P3 are given to the measurement target 2.
  • the pulsed light P1 is given to the measurement target 2 to generate the photoacoustic wave AW1.
  • the pulsed light P2 is given to the object 2 to generate the photoacoustic wave AW2.
  • the ultrasonic pulse P3 is given to the measurement object 2, it is reflected. This reflected wave is the reflected wave US.
  • the measurement target 2 is measured by the measurement unit 40 based on the reflected wave US and the photoacoustic waves AW1 and AW2.
  • the ultrasonic pulse trigger signal T3 is delayed by the delay unit 20k and given to the ultrasonic pulse output unit 32 as the movement control pulse P4.
  • the movement control pulse P4 is given to the moving unit 50 after the reflected wave US and the photoacoustic waves AW1 and AW2 are generated.
  • the moving unit 50 receives the movement control pulse P4, and moves the position at which the ultrasonic pulse P3 and the pulse lights P1 and P2 are given to the measurement target 2.
  • the moving unit While moving the position where the ultrasonic pulse P3 and the pulsed light P1 and P2 are given to the measurement target 2 by 50, the artifact signal is excluded and the measurement is performed using the ultrasonic output unit 32 and the plurality of pulsed light output units 30a and 30b. can do.
  • the fifth embodiment corresponds to the first embodiment in which the moving unit 50 is added.
  • the moving unit 50 may be added to the second to fourth embodiments.
  • a plurality of further pulse lights P1 and P2 and an ultrasonic pulse P3 may be output after the falling of the movement control pulse P4.
  • FIG. 12 is a functional block diagram showing a configuration of a pulse output time point control unit 20 according to a modification of the fifth embodiment.
  • the movement control pulse P4 is also applied to the pulse output unit 10.
  • the pulse output unit 10 detects the falling of the movement control pulse P4 after outputting the trigger signal T1. After the detection, another trigger signal T1 is output. As a result, after the falling of the movement control pulse P4, a plurality of further pulse lights P1 and P2 and an ultrasonic pulse P3 are output.
  • the above embodiment can be realized as follows.
  • a computer having a CPU, a hard disk, a medium (a floppy (registered trademark) disk, a CD-ROM, etc.) reader and a medium storing the programs for realizing the above-mentioned parts, for example, the pulse output point control unit 20 and the measuring unit 40 Read and install on the hard disk. Even with such a method, the above functions can be realized.

Abstract

This light ultrasound measurement device is provided with an ultrasonic pulse output unit, multiple pulse light output units, a pulse output timing control unit, and a measurement unit. The ultrasonic pulse output unit outputs an ultrasonic pulse. The multiple pulse light output units output pulse light beams having different wavelengths. The pulse output timing control unit controls the timing of the output of the ultrasonic pulse and each of the multiple pulse light beams, so as to prevent any overlap among the output times of the ultrasonic pulse and each of the multiple pulse light beams. The measurement unit measures an object to be measured on the basis of a reflection wave generated by reflection of the ultrasonic pulse at the object to be measured and a photoacoustic wave generated at the object to be measured by the pulse light beams.

Description

光超音波測定装置、方法、プログラム、記録媒体Optical ultrasonic measurement device, method, program, recording medium
 本発明は、光音響波および超音波の測定に関する。 The present invention relates to the measurement of photoacoustic waves and ultrasound.
 従来より、パルス光を被測定物(例えば、生体)に照射することにより得られる光音響信号を測定する光音響測定装置が知られている。例えば、特許文献1および2には、複数の光源を有する光音響測定装置が開示されている。非特許文献1には、光音響測定装置の一種であるAR-PAMが開示されている。 2. Description of the Related Art Conventionally, a photoacoustic measurement apparatus is known which measures a photoacoustic signal obtained by irradiating pulsed light onto a measured object (for example, a living body). For example, Patent Documents 1 and 2 disclose a photoacoustic measurement device having a plurality of light sources. Non-Patent Document 1 discloses AR-PAM, which is a type of photoacoustic measurement device.
 また、特許文献3には、照明光発生部および超音波発生部を一つずつ用いて、被測定物を測定する測定装置が開示されている。 Further, Patent Document 3 discloses a measurement apparatus that measures an object using an illumination light generation unit and an ultrasonic wave generation unit one by one.
特開2016-047114号公報JP, 2016-047114, A 特開2011-229660号公報JP, 2011-229660, A 国際公開第2010/095487号International Publication No. 2010/095487
 しかしながら、超音波発生部および複数のパルス光源を用いた測定装置は無い。 However, there is no measuring device using an ultrasonic wave generator and a plurality of pulse light sources.
 そこで、本発明は、超音波発生部および複数のパルス光源を用いて測定することを課題とする。 Then, this invention makes it a subject to measure using an ultrasonic wave generation part and several pulse light sources.
 本発明にかかる光超音波測定装置は、超音波パルスを出力する超音波パルス出力部と、波長が異なるパルス光を出力する複数のパルス光出力部と、前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御部と、前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定部とを備えるように構成される。 An optical ultrasonic measurement device according to the present invention includes an ultrasonic pulse output unit that outputs an ultrasonic pulse, a plurality of pulsed light output units that output pulsed light having different wavelengths, the ultrasonic pulse, and a plurality of the pulsed light. A pulse output time point control unit for controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output, so that the time when each of the ultrasonic waves is output does not overlap with each other; It comprises so that it may comprise a measurement part which measures the measurement object based on a reflected wave and a photoacoustic wave generated in the measurement object by the pulse light.
 上記のように構成された光超音波測定装置によれば、超音波パルス出力部が、超音波パルスを出力する。複数のパルス光出力部が、波長が異なるパルス光を出力する。パルス出力時点制御部が、前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御する。測定部が、前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する。 According to the optical ultrasonic measurement device configured as described above, the ultrasonic pulse output unit outputs an ultrasonic pulse. The plurality of pulsed light output units output pulsed light having different wavelengths. The pulse output time point control unit controls the time point when each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights is output does not overlap with each other. Control. A measurement unit measures the measurement object based on a reflected wave in which the ultrasonic pulse is reflected on the measurement object and a photoacoustic wave generated on the measurement object by the pulse light.
 なお、本発明にかかる光超音波測定装置は、トリガ信号が、超音波パルス用トリガ信号および複数のパルス光用トリガ信号からなり、前記超音波パルス用トリガ信号が、前記超音波パルスを発生させるために、前記超音波パルス出力部に与えられ、前記パルス光用トリガ信号の各々が、前記パルス光を発生させるために、前記パルス光出力部の各々に与えられるようにしてもよい。 In the optical ultrasonic measurement device according to the present invention, the trigger signal includes an ultrasonic pulse trigger signal and a plurality of pulse light trigger signals, and the ultrasonic pulse trigger signal generates the ultrasonic pulse. In order to generate the pulse light, each of the pulse light trigger signals may be supplied to each of the pulse light output units.
 なお、本発明にかかる光超音波測定装置は、前記パルス出力時点制御部が、ある一つの前記トリガ信号を遅延させて、別の一つの前記トリガ信号とするトリガ信号遅延部を有するようにしてもよい。 In the optical ultrasonic measurement device according to the present invention, the pulse output time point control unit has a trigger signal delay unit that delays one of the trigger signals into another one of the trigger signals. It is also good.
 なお、本発明にかかる光超音波測定装置は、前記パルス出力時点制御部がある一つの前記パルス光出力部が前記パルス光を出力した時点に同期して出力する出力同期トリガ信号を遅延させて、ある一つの前記トリガ信号とする出力同期トリガ信号遅延部を有するようにしてもよい。 In the optical ultrasonic measurement device according to the present invention, an output synchronization trigger signal that is output in synchronization with a point in time when one of the pulse light output parts having the pulse output time point control part outputs the pulse light is delayed An output synchronization trigger signal delay unit may be provided as one certain trigger signal.
 なお、本発明にかかる光超音波測定装置は、前記パルス出力時点制御部が、前記パルス光を光電変換した電気パルスを遅延させて、ある一つの前記トリガ信号とする電気パルス遅延部を有するようにしてもよい。 In the optical ultrasonic measurement device according to the present invention, the pulse output time point control unit may include an electric pulse delay unit that delays an electric pulse obtained by photoelectrically converting the pulse light to generate one certain trigger signal. You may
 なお、本発明にかかる光超音波測定装置は、ある一つの前記パルス光出力部が、別の一つの前記パルス光出力部の出力する前記パルス光を受けて波長を変換して出力するものであり、別の一つの前記パルス光出力部の出力を、ある一つの前記パルス光出力部および前記測定対象のいずれに与えるかを切り替えることができる光スイッチを備えるようにしてもよい。 In the optical ultrasonic measurement device according to the present invention, one of the pulsed light output units receives the pulsed light output from another one of the pulsed light output units, converts the wavelength, and outputs the converted light. Alternatively, an optical switch may be provided which can switch which one of the pulse light output part and the measurement object the output of another one of the pulse light output parts is to be provided.
 なお、本発明にかかる光超音波測定装置は、移動制御パルスを受けて、前記超音波パルスおよび前記パルス光が前記測定対象に与えられる位置を移動させる移動部を備え、前記パルス出力時点制御部が、前記移動制御パルス、前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記移動制御パルス、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するようにしてもよい。 The optical ultrasonic measurement device according to the present invention includes a moving unit that receives a movement control pulse and moves a position at which the ultrasonic pulse and the pulse light are given to the measurement target, and the pulse output time point control unit Each of the movement control pulse, the ultrasonic pulse, and the plurality of pulsed lights is such that the time during which each of the movement control pulse, the ultrasonic pulse, and the plurality of pulsed lights is output does not overlap with each other. The point in time of output may be controlled.
 なお、本発明にかかる光超音波測定装置は、前記移動制御パルスの立下りよりも後で、さらに別の前記超音波パルスおよび複数の前記パルス光の各々が出力されるようにしてもよい。 In the optical ultrasonic measurement apparatus according to the present invention, each of the other ultrasonic pulse and the plurality of pulse lights may be output after the falling of the movement control pulse.
 本発明は、超音波パルスを出力する超音波パルス出力部と、波長が異なるパルス光を出力する複数のパルス光出力部とを有する光超音波測定装置による光超音波測定方法であって、前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御工程と、前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定工程とを備えた光超音波測定方法である。 The present invention is an optical ultrasonic measurement method by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths, A pulse output time point control step of controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights is output does not overlap each other; A measuring method of an optical ultrasonic wave, comprising: a measuring step of measuring the object to be measured based on a reflected wave in which the ultrasonic pulse is reflected on the object to be measured and a photoacoustic wave generated on the object to be measured by the pulse light.
 本発明は、超音波パルスを出力する超音波パルス出力部と、波長が異なるパルス光を出力する複数のパルス光出力部とを有する光超音波測定装置による光超音波測定処理をコンピュータに実行させるためのプログラムであって、前記光超音波測定処理が、前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御工程と、前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定工程とを備えたプログラムである。 The present invention causes a computer to execute an optical ultrasonic measurement process by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths. The optical ultrasonic measurement process is configured to prevent the ultrasonic pulse and the plurality of pulsed lights from being output for a period of time that the ultrasonic pulse and the plurality of pulsed lights do not overlap each other. A pulse output time point control step of controlling a time point at which each of the plurality of pulses is output, a reflected wave in which the ultrasonic pulse is reflected at the measurement object, and a photoacoustic wave generated in the measurement object by the pulse light It is a program provided with the measurement process to measure.
 本発明は、超音波パルスを出力する超音波パルス出力部と、波長が異なるパルス光を出力する複数のパルス光出力部とを有する光超音波測定装置による光超音波測定処理をコンピュータに実行させるためのプログラムを記録したコンピュータによって読み取り可能な記録媒体であって、前記光超音波測定処理が、前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御工程と、前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定工程とを備えた記録媒体である。 The present invention causes a computer to execute an optical ultrasonic measurement process by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths. A computer readable recording medium having recorded thereon a program for performing the optical ultrasonic measurement process so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights is output do not overlap each other A pulse output time point control step of controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output, and generation of the ultrasonic pulse in the measurement target by a reflected wave reflected from the measurement target and the pulse light And a measurement step of measuring the measurement target based on the photoacoustic wave.
本発明の第一の実施形態にかかる光超音波測定装置1の構成を示す機能ブロック図である。It is a functional block diagram showing composition of optical ultrasonic measurement equipment 1 concerning a first embodiment of the present invention. 第一の実施形態にかかるパルス出力時点制御部20の構成を示す機能ブロック図である。It is a functional block diagram showing composition of pulse output time point control part 20 concerning a first embodiment. 第一の実施形態にかかるトリガ信号T1、T2、T3のタイミングチャートである。5 is a timing chart of trigger signals T1, T2 and T3 according to the first embodiment. 第一の実施形態にかかる複数のパルス光P1、P2および超音波パルスP3のタイミングチャートである。It is a timing chart of a plurality of pulse lights P1 and P2 concerning a first embodiment, and an ultrasonic pulse P3. 第二の実施形態にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。It is a functional block diagram which shows the structure of the pulse output time point control part 20 in the optical ultrasonic measurement apparatus 1 concerning 2nd embodiment. 第二の実施形態の変形例にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。It is a functional block diagram which shows the structure of the pulse output time point control part 20 in the optical ultrasonic measurement apparatus 1 concerning the modification of 2nd embodiment. 第三の実施形態にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。It is a functional block diagram which shows the structure of the pulse output time-point control part 20 in the optical ultrasonic measurement apparatus 1 concerning 3rd embodiment. 第四の実施形態にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。It is a functional block diagram which shows the structure of the pulse output time point control part 20 in the optical ultrasound measuring apparatus 1 concerning 4th embodiment. 第五の実施形態にかかる光超音波測定装置1の構成を示す機能ブロック図である。It is a functional block diagram which shows the structure of the optical ultrasonic measurement apparatus 1 concerning 5th embodiment. 第五の実施形態にかかるパルス出力時点制御部20の構成を示す機能ブロック図である。It is a functional block diagram which shows the structure of the pulse output time point control part 20 concerning 5th embodiment. 第五の実施形態にかかる複数のパルス光P1、P2、超音波パルスP3および光音響波AW1、AW2、反射波USのタイミングチャートである。It is a timing chart of a plurality of pulse lights P1 and P2, ultrasonic pulse P3 and photoacoustic waves AW1 and AW2, and reflected wave US according to the fifth embodiment. 第五の実施形態の変形例にかかるパルス出力時点制御部20の構成を示す機能ブロック図である。It is a functional block diagram showing composition of pulse output time point control part 20 concerning a modification of a 5th embodiment.
 以下、本発明の実施形態を図面を参照しながら説明する。 Hereinafter, embodiments of the present invention will be described with reference to the drawings.
 第一の実施形態
 図1は、本発明の第一の実施形態にかかる光超音波測定装置1の構成を示す機能ブロック図である。
First Embodiment FIG. 1 is a functional block diagram showing a configuration of an optical ultrasonic measurement apparatus 1 according to a first embodiment of the present invention.
 第一の実施形態にかかる光超音波測定装置1は、測定対象2(例えば、人体であるが、それに限定されない)を測定するためのものであり、パルス出力部10、パルス出力時点制御部20、パルス光出力部30a、30b、超音波パルス出力部32、測定部40を備える。 The optical ultrasonic measurement device 1 according to the first embodiment is for measuring a measurement target 2 (for example, a human body but is not limited thereto), and the pulse output unit 10 and the pulse output time point control unit 20 , Pulse light output units 30a and 30b, an ultrasonic pulse output unit 32, and a measurement unit 40.
 パルス出力部10は、電気パルス(パルス光用トリガ信号T1と同じ)を出力する。 The pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1).
 複数のパルス光出力部30a、30bは、波長が異なるパルス光P1、P2を出力する。なお、図1においては、パルス光出力部30a、30bが2個設けられているが、3個以上設けられていてもよい。超音波パルス出力部32は、超音波パルスP3を出力する。 The plurality of pulse light output units 30a and 30b output pulse lights P1 and P2 having different wavelengths. Although two pulse light output units 30 a and 30 b are provided in FIG. 1, three or more pulse light output units may be provided. The ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
 なお、パルス光用トリガ信号T1、T2の各々が、パルス光P1、P2を発生させるために、パルス光出力部30a、30bの各々に与えられる。パルス光出力部30aは、パルス光用トリガ信号T1に同期して、パルス光P1を発生し、測定対象2に与える。パルス光出力部30bは、パルス光用トリガ信号T2に同期して、パルス光P2を発生し、測定対象2に与える。 Note that each of the pulse light trigger signals T1 and T2 is given to each of the pulse light output units 30a and 30b in order to generate the pulse lights P1 and P2. The pulse light output unit 30 a generates the pulse light P 1 in synchronization with the pulse light trigger signal T 1 and applies the pulse light P 1 to the measurement target 2. The pulse light output unit 30 b generates the pulse light P 2 in synchronization with the pulse light trigger signal T 2 and applies the pulse light P 2 to the measurement target 2.
 超音波パルス用トリガ信号T3が、超音波パルスP3を発生させるために超音波パルス出力部32に与えられる。超音波パルス出力部32は、超音波パルス用トリガ信号T3に同期して、超音波パルスP3を発生し、測定対象2に与える。 An ultrasonic pulse trigger signal T3 is applied to the ultrasonic pulse output unit 32 to generate an ultrasonic pulse P3. The ultrasonic pulse output unit 32 generates an ultrasonic pulse P3 in synchronization with the ultrasonic pulse trigger signal T3, and applies the ultrasonic pulse P3 to the measurement target 2.
 超音波パルス用トリガ信号T3および複数のパルス光用トリガ信号T1、T2を、トリガ信号という。 The ultrasonic pulse trigger signal T3 and the plurality of pulse light trigger signals T1 and T2 are referred to as trigger signals.
 測定部40は、超音波パルスが測定対象2において反射された反射波USおよびパルス光P1、P2により測定対象2において発生した光音響波AW1、AW2に基づき測定対象2を測定する。 The measurement unit 40 measures the measurement object 2 based on the reflected wave US in which the ultrasonic pulse is reflected at the measurement object 2 and the photoacoustic waves AW1 and AW2 generated in the measurement object 2 by the pulse lights P1 and P2.
 なお、パルス光P1、P2を測定対象2に照射し、測定部40にて光音響波AW1、AW2を受けるための構造としては、例えば、AR-PAMがあるが、AR-PAMに限定されるものではない。 In addition, although there exists AR-PAM as a structure for irradiating pulsed light P1 and P2 to measurement object 2, and receiving photoacoustic wave AW1 and AW2 in measurement part 40, for example, it is limited to AR-PAM It is not a thing.
 パルス出力時点制御部20は、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しないように、超音波パルスP3および複数のパルス光P1、P2の各々が出力される時点を制御する(図4参照)。 The pulse output time point control unit 20 controls each of the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 so that the time during which each of the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 is output does not overlap with each other. Control the output time point (see FIG. 4).
 図2は、第一の実施形態にかかるパルス出力時点制御部20の構成を示す機能ブロック図である。パルス出力時点制御部20は、遅延部(トリガ信号遅延部)20a、20bを有する。 FIG. 2 is a functional block diagram showing the configuration of the pulse output point control unit 20 according to the first embodiment. The pulse output time point control unit 20 has delay units (trigger signal delay units) 20a and 20b.
 パルス出力時点制御部20は、パルス出力部10から電気パルス(パルス光用トリガ信号T1と同じ)を受けて、そのまま出力し、パルス光出力部30aに与える。 The pulse output time point control unit 20 receives an electric pulse (same as the pulse light trigger signal T1) from the pulse output unit 10, outputs it as it is, and supplies it to the pulse light output unit 30a.
 遅延部(トリガ信号遅延部)20aは、ある一つのトリガ信号T1を遅延させて、別の一つのトリガ信号T2として、パルス光出力部30bおよび遅延部20bに与える。遅延部(トリガ信号遅延部)20bは、ある一つのトリガ信号T2を遅延させて、別の一つのトリガ信号T3として、超音波パルス出力部32に与える。 The delay unit (trigger signal delay unit) 20a delays a certain trigger signal T1 and supplies it as a single other trigger signal T2 to the pulse light output unit 30b and the delay unit 20b. The delay unit (trigger signal delay unit) 20b delays a certain trigger signal T2 and supplies the delayed signal to the ultrasonic pulse output unit 32 as another trigger signal T3.
 図3は、第一の実施形態にかかるトリガ信号T1、T2、T3のタイミングチャートである。トリガ信号T1が遅延してトリガ信号T2となり、トリガ信号T2が遅延してトリガ信号T3となる。トリガ信号T1、T2、T3が出力されている時間(Highになっている時間)は重複していない。 FIG. 3 is a timing chart of trigger signals T1, T2 and T3 according to the first embodiment. The trigger signal T1 is delayed to become a trigger signal T2, and the trigger signal T2 is delayed to become a trigger signal T3. The time during which the trigger signals T1, T2, and T3 are output (the time when it is High) does not overlap.
 図4は、第一の実施形態にかかる複数のパルス光P1、P2および超音波パルスP3のタイミングチャートである。 FIG. 4 is a timing chart of a plurality of pulse lights P1 and P2 and an ultrasonic pulse P3 according to the first embodiment.
 トリガ信号T1、T2、T3に同期して、複数のパルス光P1、P2および超音波パルスP3が出力される。パルス光P2の立ち上がりは、パルス光P1の立ち上がりよりもΔt1遅れている。Δt1は、パルス光P1のパルス幅W1よりも大きい。超音波パルスP3の立ち上がりは、パルス光P2の立ち上がりよりもΔt2遅れている。Δt2は、パルス光P2のパルス幅W2よりも大きい。このように、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しない。 A plurality of pulse lights P1 and P2 and an ultrasonic pulse P3 are output in synchronization with the trigger signals T1, T2 and T3. The rise of the pulsed light P2 is delayed by Δt1 from the rise of the pulsed light P1. Δt1 is larger than the pulse width W1 of the pulsed light P1. The rise of the ultrasonic pulse P3 is delayed by Δt2 from the rise of the pulsed light P2. Δt2 is larger than the pulse width W2 of the pulsed light P2. Thus, the times at which each of the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 is output do not overlap each other.
 なお、図4においては、パルス光P1の後にパルス光P2が出力され、パルス光P2の後に超音波パルスP3が出力されている。しかし、必ずしも、パルス光P1、P2、超音波パルスP3の順番で出力されていなければならないというものではなく、出力の順番は任意である。 In FIG. 4, the pulse light P2 is output after the pulse light P1, and the ultrasonic pulse P3 is output after the pulse light P2. However, it does not necessarily have to be output in the order of the pulse lights P1 and P2 and the ultrasonic pulse P3, and the order of the output is arbitrary.
 次に、第一の実施形態の動作を説明する。 Next, the operation of the first embodiment will be described.
 まず、パルス出力部10は、電気パルス(パルス光用トリガ信号T1と同じ)を出力する。電気パルスは、パルス出力時点制御部20を通過して、パルス光用トリガ信号T1として、パルス光出力部30aに与えられる。 First, the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1). The electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
 パルス光用トリガ信号T1は、遅延部20aにより遅延され、パルス光用トリガ信号T2として、パルス光出力部30bに与えられる。 The pulse light trigger signal T1 is delayed by the delay unit 20a and given to the pulse light output unit 30b as a pulse light trigger signal T2.
 パルス光用トリガ信号T2は、遅延部20bにより遅延され、超音波パルス用トリガ信号T3として、超音波パルス出力部32に与えられる。 The pulse light trigger signal T2 is delayed by the delay unit 20b and given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3.
 パルス光出力部30a、30bは、それそれ、波長が異なるパルス光P1、P2を出力する。超音波パルス出力部32は、超音波パルスP3を出力する。 The pulsed light output units 30a and 30b respectively output pulsed lights P1 and P2 having different wavelengths. The ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
 パルス光P1、P2および超音波パルスP3は、測定対象2に与えられる。パルス光P1が測定対象2に与えられることにより、光音響波AW1が発生する。パルス光P2が測定対象2に与えられることにより、光音響波AW2が発生する。超音波パルスP3が測定対象2に与えられると、反射される。この反射波が反射波USである。 The pulse lights P1 and P2 and the ultrasonic pulse P3 are given to the measurement target 2. The pulsed light P1 is given to the measurement target 2 to generate the photoacoustic wave AW1. The pulsed light P2 is given to the object 2 to generate the photoacoustic wave AW2. When the ultrasonic pulse P3 is given to the measurement object 2, it is reflected. This reflected wave is the reflected wave US.
 反射波USおよび光音響波AW1、AW2に基づき、測定部40によって測定対象2が測定される。 The measurement target 2 is measured by the measurement unit 40 based on the reflected wave US and the photoacoustic waves AW1 and AW2.
 第一の実施形態によれば、パルス出力時点制御部20によって、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しないので、アーティファクト信号を除外し、超音波出力部32および複数のパルス光出力部30a、30bを用いて測定することができる。 According to the first embodiment, since the time during which each of the ultrasonic pulse P3 and the plurality of pulse lights P1 and P2 is output does not overlap each other by the pulse output time point control unit 20, the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
 第二の実施形態
 第二の実施形態にかかる光超音波測定装置1は、ある一つのパルス光出力部30a(30b)がパルス光P1(P2)を出力した時点に同期して出力する出力同期トリガ信号T1out(T2out)を遅延させて、ある一つの前記トリガ信号T2(T3)とする点が、第一の実施形態にかかる光超音波測定装置1と異なる。
Second Embodiment The optical ultrasonic measurement apparatus 1 according to the second embodiment is an output synchronization in which one pulse light output unit 30a (30b) outputs the pulse light P1 (P2) in synchronization with the output time. The point that the trigger signal T1out (T2out) is delayed to form one certain trigger signal T2 (T3) is different from the optical ultrasonic measurement device 1 according to the first embodiment.
 図5は、第二の実施形態にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。なお、第二の実施形態にかかる光超音波測定装置1の構成要素のうち、第一の実施形態と同様なものは、同一の符号を付して説明を省略する。測定対象2、パルス出力部10、超音波パルス出力部32および測定部40は、第一の実施形態と同様であり、説明を省略する。 FIG. 5 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the second embodiment. Note that among the constituent elements of the optical ultrasonic measurement device 1 according to the second embodiment, the same parts as those in the first embodiment are given the same reference numerals, and descriptions thereof will be omitted. The measurement target 2, the pulse output unit 10, the ultrasonic pulse output unit 32, and the measurement unit 40 are the same as in the first embodiment, and thus the description thereof is omitted.
 第二の実施形態にかかるパルス光出力部30a、30bは、第一の実施形態と同様であるが、出力同期トリガ信号T1out、T2outを出力する点が、第一の実施形態と異なる。 The pulse light output units 30a and 30b according to the second embodiment are the same as the first embodiment, but are different from the first embodiment in that the output synchronization trigger signals T1out and T2out are output.
 第二の実施形態にかかるパルス光出力部30aは、パルス光P1を出力した時点に同期して出力同期トリガ信号T1outを出力する。第二の実施形態にかかるパルス光出力部30bは、パルス光P2を出力した時点に同期して出力同期トリガ信号T2outを出力する。 The pulsed light output unit 30a according to the second embodiment outputs the output synchronization trigger signal T1out in synchronization with the time when the pulsed light P1 is output. The pulsed light output unit 30b according to the second embodiment outputs the output synchronization trigger signal T2out in synchronization with the time when the pulsed light P2 is output.
 第二の実施形態にかかるパルス出力時点制御部20は、第一の実施形態と同様であるが、遅延部(出力同期トリガ信号遅延部)20c、20dを有する。 The pulse output time point control unit 20 according to the second embodiment is the same as the first embodiment, but includes delay units (output synchronization trigger signal delay units) 20c and 20d.
 遅延部(出力同期トリガ信号遅延部)20cは、出力同期トリガ信号T1outを遅延させて、トリガ信号T2とする。遅延部(出力同期トリガ信号遅延部)20dは、出力同期トリガ信号T2outを遅延させて、トリガ信号T3とする。 The delay unit (output synchronization trigger signal delay unit) 20c delays the output synchronization trigger signal T1out into a trigger signal T2. The delay unit (output synchronization trigger signal delay unit) 20d delays the output synchronization trigger signal T2out to a trigger signal T3.
 なお、トリガ信号T1、T2、T3のタイミングチャートは第一の実施形態と同様であり(図3参照)、パルス光P1、P2、超音波パルスP3のタイミングチャートは第一の実施形態と同様であるので(図4参照)、説明を省略する。 The timing chart of the trigger signals T1, T2 and T3 is the same as in the first embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the first embodiment. Since there is (see FIG. 4), the description is omitted.
 次に、第二の実施形態の動作を説明する。 Next, the operation of the second embodiment will be described.
 まず、パルス出力部10は、電気パルス(パルス光用トリガ信号T1と同じ)を出力する。電気パルスは、パルス出力時点制御部20を通過して、パルス光用トリガ信号T1として、パルス光出力部30aに与えられる。 First, the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1). The electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
 パルス光出力部30aは、パルス光P1を出力する。さらに、パルス光出力部30aは、パルス光P1を出力した時点に同期して出力同期トリガ信号T1outを出力する。出力同期トリガ信号T1outは、遅延部20cにより遅延され、パルス光用トリガ信号T2として、パルス光出力部30bに与えられる。 The pulsed light output unit 30a outputs pulsed light P1. Furthermore, the pulse light output unit 30a outputs the output synchronization trigger signal T1out in synchronization with the time point when the pulse light P1 is output. The output synchronization trigger signal T1out is delayed by the delay unit 20c and given to the pulse light output unit 30b as the pulse light trigger signal T2.
 パルス光出力部30bは、パルス光P2を出力する。さらに、パルス光出力部30bは、パルス光P2を出力した時点に同期して出力同期トリガ信号T2outを出力する。出力同期トリガ信号T2outは、遅延部20dにより遅延され、超音波パルス用トリガ信号T3として、超音波パルス出力部32に与えられる。 The pulsed light output unit 30b outputs pulsed light P2. Furthermore, the pulse light output unit 30b outputs the output synchronization trigger signal T2out in synchronization with the time when the pulse light P2 is output. The output synchronization trigger signal T2out is delayed by the delay unit 20d and given to the ultrasonic pulse output unit 32 as the ultrasonic pulse trigger signal T3.
 超音波パルス出力部32は、超音波パルスP3を出力する。 The ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
 これ以降の動作は、第一の実施形態と同様であり説明を省略する。 The subsequent operation is the same as that of the first embodiment, and the description will be omitted.
 第二の実施形態によれば、パルス出力時点制御部20によって、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しないので、アーティファクト信号を除外し、超音波出力部32および複数のパルス光出力部30a、30bを用いて測定することができる。 According to the second embodiment, since the time during which each of the ultrasonic pulse P3 and the plurality of pulse lights P1 and P2 is output does not overlap each other by the pulse output time point control unit 20, the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
 なお、第二の実施形態においては、パルス光出力部30aおよびパルス光出力部30bの双方が、出力同期トリガ信号を出力する。しかし、パルス光出力部30aのみが、出力同期トリガ信号を出力することも考えられる。そこで、パルス光出力部30aのみが、出力同期トリガ信号を出力する場合を変形例として、図6を参照して説明する。 In the second embodiment, both the pulse light output unit 30a and the pulse light output unit 30b output an output synchronization trigger signal. However, it is also conceivable that only the pulse light output unit 30a outputs the output synchronization trigger signal. Therefore, the case where only the pulse light output unit 30a outputs the output synchronization trigger signal will be described as a modified example with reference to FIG.
 図6は、第二の実施形態の変形例にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。 FIG. 6 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the modification of the second embodiment.
 変形例にかかるパルス出力時点制御部20は、遅延部20c、20eを有する。遅延部20cは、第二の実施形態と同様である。遅延部(出力同期トリガ信号遅延部)20eは、出力同期トリガ信号T1outを遅延させて、ある一つのトリガ信号T3とする。 The pulse output time point control unit 20 according to the modification includes delay units 20c and 20e. The delay unit 20c is similar to that of the second embodiment. The delay unit (output synchronization trigger signal delay unit) 20e delays the output synchronization trigger signal T1out to a certain trigger signal T3.
 なお、トリガ信号T1、T2、T3のタイミングチャートは第二の実施形態と同様であり(図3参照)、パルス光P1、P2、超音波パルスP3のタイミングチャートは第二の実施形態と同様であるので(図4参照)、説明を省略する。 The timing chart of the trigger signals T1, T2 and T3 is the same as in the second embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the second embodiment. Since there is (see FIG. 4), the description is omitted.
 第三の実施形態
 第三の実施形態にかかる光超音波測定装置1は、パルス光P1(P2)を光電変換した電気パルスを遅延させて、ある一つのトリガ信号T2(T3)とする点が、第一の実施形態にかかる光超音波測定装置1と異なる。
Third Embodiment The optical ultrasonic measurement device 1 according to the third embodiment delays an electric pulse obtained by photoelectrically converting the pulse light P1 (P2) into one trigger signal T2 (T3). This is different from the optical ultrasonic measurement device 1 according to the first embodiment.
 図7は、第三の実施形態にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。なお、第三の実施形態にかかる光超音波測定装置1の構成要素のうち、第一の実施形態と同様なものは、同一の符号を付して説明を省略する。測定対象2、パルス出力部10、パルス光出力部30a、30b、超音波パルス出力部32および測定部40は、第一の実施形態と同様であり、説明を省略する。 FIG. 7 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the third embodiment. Note that among the constituent elements of the optical ultrasonic measurement device 1 according to the third embodiment, the same parts as those in the first embodiment are given the same reference numerals, and descriptions thereof will be omitted. The measurement target 2, the pulse output unit 10, the pulse light output units 30a and 30b, the ultrasonic pulse output unit 32, and the measurement unit 40 are the same as those in the first embodiment, and thus the description thereof is omitted.
 第三の実施形態にかかる光超音波測定装置1は、フォトダイオードPD1、PD2を備える。フォトダイオードPD1は、パルス光P1を光電変換した電気パルスを出力する。フォトダイオードPD2は、パルス光P2を光電変換した電気パルスを出力する。なお、光電変換できるものであれば、フォトダイオードPD1、PD2にかえて使用することができる。 The optical ultrasonic measurement device 1 according to the third embodiment includes the photodiodes PD1 and PD2. The photodiode PD1 outputs an electrical pulse obtained by photoelectrically converting the pulse light P1. The photodiode PD2 outputs an electrical pulse obtained by photoelectrically converting the pulse light P2. In addition, as long as photoelectric conversion can be performed, the photodiodes PD1 and PD2 can be used instead.
 第三の実施形態にかかるパルス出力時点制御部20は、第一の実施形態と同様であるが、遅延部(電気パルス遅延部)20f、20gを有する。 The pulse output time point control unit 20 according to the third embodiment is the same as the first embodiment, but includes delay units (electric pulse delay units) 20f and 20g.
 遅延部(電気パルス遅延部)20fは、フォトダイオードPD1の出力を遅延させて、トリガ信号T2とする。遅延部(電気パルス遅延部)20gは、フォトダイオードPD2の出力を遅延させて、トリガ信号T3とする。 The delay unit (electric pulse delay unit) 20f delays the output of the photodiode PD1 to generate a trigger signal T2. The delay unit (electric pulse delay unit) 20g delays the output of the photodiode PD2 to generate a trigger signal T3.
 なお、トリガ信号T1、T2、T3のタイミングチャートは第一の実施形態と同様であり(図3参照)、パルス光P1、P2、超音波パルスP3のタイミングチャートは第一の実施形態と同様であるので(図4参照)、説明を省略する。 The timing chart of the trigger signals T1, T2 and T3 is the same as in the first embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the first embodiment. Since there is (see FIG. 4), the description is omitted.
 次に、第三の実施形態の動作を説明する。 Next, the operation of the third embodiment will be described.
 まず、パルス出力部10は、電気パルス(パルス光用トリガ信号T1と同じ)を出力する。電気パルスは、パルス出力時点制御部20を通過して、パルス光用トリガ信号T1として、パルス光出力部30aに与えられる。 First, the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1). The electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
 パルス光出力部30aは、パルス光P1を出力する。パルス光P1は、フォトダイオードPD1により光電変換され、電気パルスとなり、遅延部20fにより遅延され、パルス光用トリガ信号T2として、パルス光出力部30bに与えられる。 The pulsed light output unit 30a outputs pulsed light P1. The pulse light P1 is photoelectrically converted by the photodiode PD1 into an electric pulse, delayed by the delay unit 20f, and given to the pulse light output unit 30b as a pulse light trigger signal T2.
 パルス光出力部30bは、パルス光P2を出力する。パルス光P2は、フォトダイオードPD2により光電変換され、電気パルスとなり、遅延部20gにより遅延され、超音波パルス用トリガ信号T3として、超音波パルス出力部32に与えられる。 The pulsed light output unit 30b outputs pulsed light P2. The pulse light P2 is photoelectrically converted by the photodiode PD2, becomes an electric pulse, is delayed by the delay unit 20g, and is given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3.
 超音波パルス出力部32は、超音波パルスP3を出力する。 The ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
 これ以降の動作は、第一の実施形態と同様であり説明を省略する。 The subsequent operation is the same as that of the first embodiment, and the description will be omitted.
 第三の実施形態によれば、パルス出力時点制御部20によって、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しないので、アーティファクト信号を除外し、超音波出力部32および複数のパルス光出力部30a、30bを用いて測定することができる。 According to the third embodiment, since the time during which each of the ultrasonic pulse P3 and the plurality of pulse lights P1 and P2 is output does not overlap each other by the pulse output time point control unit 20, the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
 第四の実施形態
 第四の実施形態にかかる光超音波測定装置1は、光スイッチ34を用いて、パルス光P1およびP2の測定対象2への出力を切り替える点が、第一の実施形態にかかる光超音波測定装置1と異なる。
Fourth Embodiment The optical ultrasonic measurement device 1 according to the fourth embodiment uses the optical switch 34 to switch the output of the pulse lights P1 and P2 to the measurement target 2 in the first embodiment. This differs from the optical ultrasonic measurement device 1.
 図8は、第四の実施形態にかかる光超音波測定装置1におけるパルス出力時点制御部20の構成を示す機能ブロック図である。なお、第四の実施形態にかかる光超音波測定装置1の構成要素のうち、第一の実施形態と同様なものは、同一の符号を付して説明を省略する。測定対象2、パルス出力部10、パルス出力時点制御部20、パルス光出力部30a、超音波パルス出力部32および測定部40は、第一の実施形態と同様であり、説明を省略する。 FIG. 8 is a functional block diagram showing the configuration of the pulse output time point control unit 20 in the optical ultrasonic measurement device 1 according to the fourth embodiment. Among the constituent elements of the optical ultrasonic measurement apparatus 1 according to the fourth embodiment, the same parts as those of the first embodiment are denoted by the same reference numerals, and the description thereof will be omitted. The measurement target 2, the pulse output unit 10, the pulse output time point control unit 20, the pulse light output unit 30a, the ultrasonic pulse output unit 32, and the measurement unit 40 are the same as those in the first embodiment, and the description is omitted.
 第四の実施形態にかかる光超音波測定装置1は、パルス光出力部30d、光スイッチ34を備える。 The optical ultrasonic measurement device 1 according to the fourth embodiment includes a pulse light output unit 30 d and an optical switch 34.
 なお、第四の実施形態のパルス出力時点制御部20の遅延部20aの出力するトリガ信号T2は、光スイッチ34に与えられる。 The trigger signal T2 output from the delay unit 20a of the pulse output timing control unit 20 according to the fourth embodiment is supplied to the optical switch 34.
 パルス光出力部30dが、パルス光出力部30aの出力するパルス光P1を受けて波長を変換して出力する。この出力が、パルス光P2である。光スイッチ34は、パルス光出力部30aの出力P1を、パルス光出力部30dおよび測定対象2のいずれに与えるかを切り替えることができる。この切り替えは、光スイッチ34がトリガ信号T2を受けた時点に同期して行われる。 The pulsed light output unit 30d receives the pulsed light P1 output from the pulsed light output unit 30a, converts the wavelength, and outputs it. This output is the pulsed light P2. The optical switch 34 can switch which of the pulsed light output unit 30 d and the measurement target 2 the output P 1 of the pulsed light output unit 30 a is to be provided. This switching is performed in synchronization with the time when the optical switch 34 receives the trigger signal T2.
 例えば、光スイッチ34は、Highになったトリガ信号T2を受ける前は、パルス光出力部30aの出力P1を測定対象2に与える。光スイッチ34は、Highになったトリガ信号T2を受けた後は、パルス光出力部30aの出力P1をパルス光出力部30dに与える。 For example, before receiving the trigger signal T2 that has become High, the optical switch 34 applies the output P1 of the pulsed light output unit 30a to the measurement target 2. After receiving the trigger signal T2 that has become High, the optical switch 34 applies the output P1 of the pulsed light output unit 30a to the pulsed light output unit 30d.
 なお、トリガ信号T1、T2、T3のタイミングチャートは第一の実施形態と同様であり(図3参照)、パルス光P1、P2、超音波パルスP3のタイミングチャートは第一の実施形態と同様であるので(図4参照)、説明を省略する。 The timing chart of the trigger signals T1, T2 and T3 is the same as in the first embodiment (see FIG. 3), and the timing chart of the pulse lights P1 and P2 and the ultrasonic pulse P3 is the same as in the first embodiment. Since there is (see FIG. 4), the description is omitted.
 次に、第四の実施形態の動作を説明する。 Next, the operation of the fourth embodiment will be described.
 まず、パルス出力部10は、電気パルス(パルス光用トリガ信号T1と同じ)を出力する。電気パルスは、パルス出力時点制御部20を通過して、パルス光用トリガ信号T1として、パルス光出力部30aに与えられる。 First, the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1). The electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
 パルス光出力部30aは、パルス光P1を出力する。パルス光P1は、光スイッチ34を介して、測定対象2に与えられる。 The pulsed light output unit 30a outputs pulsed light P1. The pulsed light P1 is given to the measurement target 2 via the optical switch 34.
 パルス光用トリガ信号T1は、遅延部20aにより遅延され、パルス光用トリガ信号T2として、光スイッチ34に与えられる。光スイッチ34は、パルス光P1の出力先を、パルス光出力部30dに切り替える。パルス光出力部30dから、パルス光P2が出力される。 The pulse light trigger signal T1 is delayed by the delay unit 20a and given to the optical switch 34 as the pulse light trigger signal T2. The optical switch 34 switches the output destination of the pulsed light P1 to the pulsed light output unit 30d. The pulse light P2 is output from the pulse light output unit 30d.
 パルス光用トリガ信号T2は、遅延部20bにより遅延され、超音波パルス用トリガ信号T3として、超音波パルス出力部32に与えられる。超音波パルス出力部32は、超音波パルスP3を出力する。 The pulse light trigger signal T2 is delayed by the delay unit 20b and given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3. The ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
 これ以降の動作は、第一の実施形態と同様であり説明を省略する。 The subsequent operation is the same as that of the first embodiment, and the description will be omitted.
 第四の実施形態によれば、パルス出力時点制御部20によって、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しないので、アーティファクト信号を除外し、超音波出力部32および複数のパルス光出力部30a、30bを用いて測定することができる。 According to the fourth embodiment, since the time during which each of the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 is output does not overlap each other by the pulse output time point control unit 20, the artifact signal is excluded. It can measure using the sound wave output part 32 and several pulse light output parts 30a and 30b.
 第五の実施形態
 第五の実施形態にかかる光超音波測定装置1は、移動部50を備えた点が、第一の実施形態にかかる光超音波測定装置1と異なる。
Fifth Embodiment The optical ultrasonic measurement device 1 according to the fifth embodiment is different from the optical ultrasonic measurement device 1 according to the first embodiment in that a movement unit 50 is provided.
 図9は、第五の実施形態にかかる光超音波測定装置1の構成を示す機能ブロック図である。 FIG. 9 is a functional block diagram showing the configuration of the optical ultrasonic measurement device 1 according to the fifth embodiment.
 第五の実施形態にかかる光超音波測定装置1は、パルス出力部10、パルス出力時点制御部20、パルス光出力部30a、30b、超音波パルス出力部32、測定部40、移動部50を備える。移動部50以外は、第一の実施形態と同様であり、同一の符号を付して説明を省略する。 The optical ultrasonic measurement apparatus 1 according to the fifth embodiment includes a pulse output unit 10, a pulse output time point control unit 20, pulse light output units 30a and 30b, an ultrasonic pulse output unit 32, a measurement unit 40, and a moving unit 50. Prepare. The components other than the moving unit 50 are the same as in the first embodiment, and the same reference numerals are given and the description is omitted.
 移動部50は、移動制御パルスP4を受けて、超音波パルスP3およびパルス光P1、P2が測定対象2に与えられる位置を移動させる。 The moving unit 50 receives the movement control pulse P4, and moves the position at which the ultrasonic pulse P3 and the pulse lights P1 and P2 are given to the measurement target 2.
 パルス出力時点制御部20は、移動制御パルスP4、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しないように、移動制御パルスP4、超音波パルスP3および複数のパルス光P1、P2の各々が出力される時点を制御する。 The pulse output time point control unit 20 controls the movement control pulse P4, the ultrasonic pulse P3, and the movement pulse P4 so that the time during which each of the movement pulse P4, the ultrasonic pulse P3 and the plural pulse lights P1 and P2 is output does not overlap. The point in time when each of the plurality of pulsed lights P1 and P2 is output is controlled.
 図10は、第五の実施形態にかかるパルス出力時点制御部20の構成を示す機能ブロック図である。第五の実施形態にかかるパルス出力時点制御部20は、遅延部20a、20b、20kを有する。遅延部20a、20bは、第一の実施形態と同様であり、説明を省略する。 FIG. 10 is a functional block diagram showing the configuration of the pulse output time point control unit 20 according to the fifth embodiment. The pulse output timing control unit 20 according to the fifth embodiment has delay units 20a, 20b, and 20k. The delay units 20a and 20b are the same as in the first embodiment, and the description will be omitted.
 遅延部20kは、トリガ信号T3を遅延させて、移動制御パルスP4とする。 The delay unit 20k delays the trigger signal T3 to generate a movement control pulse P4.
 図11は、第五の実施形態にかかる複数のパルス光P1、P2、超音波パルスP3および光音響波AW1、AW2、反射波USのタイミングチャートである。 FIG. 11 is a timing chart of a plurality of pulse lights P1 and P2, an ultrasonic pulse P3 and photoacoustic waves AW1 and AW2 and a reflected wave US according to the fifth embodiment.
 移動制御パルスP4、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しない。しかも、光音響波AW1、AW2および反射波USが出力された後に、移動制御パルスP4が出力されている。 The times at which each of the movement control pulse P4, the ultrasonic pulse P3 and the plurality of pulsed lights P1 and P2 is output do not overlap each other. Moreover, after the photoacoustic waves AW1 and AW2 and the reflected wave US are output, the movement control pulse P4 is output.
 次に、第五の実施形態の動作を説明する。 Next, the operation of the fifth embodiment will be described.
 まず、パルス出力部10は、電気パルス(パルス光用トリガ信号T1と同じ)を出力する。電気パルスは、パルス出力時点制御部20を通過して、パルス光用トリガ信号T1として、パルス光出力部30aに与えられる。 First, the pulse output unit 10 outputs an electrical pulse (same as the pulse light trigger signal T1). The electric pulse passes through the pulse output time point control unit 20 and is given to the pulse light output unit 30a as a pulse light trigger signal T1.
 パルス光用トリガ信号T1は、遅延部20aにより遅延され、パルス光用トリガ信号T2として、パルス光出力部30bに与えられる。 The pulse light trigger signal T1 is delayed by the delay unit 20a and given to the pulse light output unit 30b as a pulse light trigger signal T2.
 パルス光用トリガ信号T2は、遅延部20bにより遅延され、超音波パルス用トリガ信号T3として、超音波パルス出力部32に与えられる。 The pulse light trigger signal T2 is delayed by the delay unit 20b and given to the ultrasonic pulse output unit 32 as an ultrasonic pulse trigger signal T3.
 パルス光出力部30a、30bは、それそれ、波長が異なるパルス光P1、P2を出力する。超音波パルス出力部32は、超音波パルスP3を出力する。 The pulsed light output units 30a and 30b respectively output pulsed lights P1 and P2 having different wavelengths. The ultrasonic pulse output unit 32 outputs an ultrasonic pulse P3.
 パルス光P1、P2および超音波パルスP3は、測定対象2に与えられる。パルス光P1が測定対象2に与えられることにより、光音響波AW1が発生する。パルス光P2が測定対象2に与えられることにより、光音響波AW2が発生する。超音波パルスP3が測定対象2に与えられると、反射される。この反射波が反射波USである。 The pulse lights P1 and P2 and the ultrasonic pulse P3 are given to the measurement target 2. The pulsed light P1 is given to the measurement target 2 to generate the photoacoustic wave AW1. The pulsed light P2 is given to the object 2 to generate the photoacoustic wave AW2. When the ultrasonic pulse P3 is given to the measurement object 2, it is reflected. This reflected wave is the reflected wave US.
 反射波USおよび光音響波AW1、AW2に基づき、測定部40によって測定対象2が測定される。 The measurement target 2 is measured by the measurement unit 40 based on the reflected wave US and the photoacoustic waves AW1 and AW2.
 超音波パルス用トリガ信号T3は、遅延部20kにより遅延され、移動制御パルスP4として、超音波パルス出力部32に与えられる。なお、反射波USおよび光音響波AW1、AW2が発生した後で、移動制御パルスP4が移動部50に与えられる。 The ultrasonic pulse trigger signal T3 is delayed by the delay unit 20k and given to the ultrasonic pulse output unit 32 as the movement control pulse P4. The movement control pulse P4 is given to the moving unit 50 after the reflected wave US and the photoacoustic waves AW1 and AW2 are generated.
 移動部50は、移動制御パルスP4を受けて、超音波パルスP3およびパルス光P1、P2が測定対象2に与えられる位置を移動させる。 The moving unit 50 receives the movement control pulse P4, and moves the position at which the ultrasonic pulse P3 and the pulse lights P1 and P2 are given to the measurement target 2.
 第五の実施形態によれば、パルス出力時点制御部20によって、移動制御パルスP4、超音波パルスP3および複数のパルス光P1、P2の各々が出力されている時間が互いに重複しないので、移動部50により超音波パルスP3およびパルス光P1、P2が測定対象2に与えられる位置を移動させながら、アーティファクト信号を除外し、超音波出力部32および複数のパルス光出力部30a、30bを用いて測定することができる。 According to the fifth embodiment, since the time during which each of the movement control pulse P4, the ultrasonic pulse P3 and the plurality of pulse lights P1 and P2 is outputted by the pulse output time point control unit 20 does not overlap with each other, the moving unit While moving the position where the ultrasonic pulse P3 and the pulsed light P1 and P2 are given to the measurement target 2 by 50, the artifact signal is excluded and the measurement is performed using the ultrasonic output unit 32 and the plurality of pulsed light output units 30a and 30b. can do.
 なお、第五の実施形態は、第一の実施形態に移動部50を追加したものに相当する。しかし、第二~第四の実施形態に移動部50を追加するようにしてもよい。 The fifth embodiment corresponds to the first embodiment in which the moving unit 50 is added. However, the moving unit 50 may be added to the second to fourth embodiments.
 また、第五の実施形態の変形例として、移動制御パルスP4の立下りよりも後で、さらに別の複数のパルス光P1、P2、超音波パルスP3が出力されるようにしてもよい。 Further, as a modification of the fifth embodiment, a plurality of further pulse lights P1 and P2 and an ultrasonic pulse P3 may be output after the falling of the movement control pulse P4.
 図12は、第五の実施形態の変形例にかかるパルス出力時点制御部20の構成を示す機能ブロック図である。 FIG. 12 is a functional block diagram showing a configuration of a pulse output time point control unit 20 according to a modification of the fifth embodiment.
 移動制御パルスP4は、パルス出力部10にも与えられる。パルス出力部10は、トリガ信号T1を出力した後、移動制御パルスP4の立下りを検知する。その検知後に、さらに別のトリガ信号T1を出力する。これにより、移動制御パルスP4の立下りよりも後で、さらに別の複数のパルス光P1、P2、超音波パルスP3が出力される。 The movement control pulse P4 is also applied to the pulse output unit 10. The pulse output unit 10 detects the falling of the movement control pulse P4 after outputting the trigger signal T1. After the detection, another trigger signal T1 is output. As a result, after the falling of the movement control pulse P4, a plurality of further pulse lights P1 and P2 and an ultrasonic pulse P3 are output.
 また、上記の実施形態は、以下のようにして実現できる。CPU、ハードディスク、メディア(フロッピー(登録商標)ディスク、CD-ROMなど)読み取り装置を備えたコンピュータに、上記の各部分、例えばパルス出力時点制御部20および測定部40を実現するプログラムを記録したメディアを読み取らせて、ハードディスクにインストールする。このような方法でも、上記の機能を実現できる。 The above embodiment can be realized as follows. A computer having a CPU, a hard disk, a medium (a floppy (registered trademark) disk, a CD-ROM, etc.) reader and a medium storing the programs for realizing the above-mentioned parts, for example, the pulse output point control unit 20 and the measuring unit 40 Read and install on the hard disk. Even with such a method, the above functions can be realized.
 P1、P2 パルス光
 P3 超音波パルス
 P4 移動制御パルス
 US 反射波
 AW1、AW2 光音響波
 T1、T2 パルス光用トリガ信号
 T1out、T2out 出力同期トリガ信号
 T3 超音波パルス用トリガ信号
 1 光超音波測定装置
 2 測定対象
 10 パルス出力部
 20 パルス出力時点制御部
 20a、20b 遅延部(トリガ信号遅延部)
 20c、20d 遅延部(出力同期トリガ信号遅延部)
 20f、20g 遅延部(電気パルス遅延部)
 30a、30b、30d パルス光出力部
 32 超音波パルス出力部
 34 光スイッチ
 40 測定部
 50 移動部
P1, P2 pulse light P3 ultrasonic pulse P4 movement control pulse US reflected wave AW1, AW2 photoacoustic wave T1, T2 trigger signal for pulse light T1out, T2out output synchronous trigger signal T3 ultrasonic pulse trigger signal 1 optical ultrasonic measurement device 2 measurement object 10 pulse output unit 20 pulse output time point control unit 20a, 20b delay unit (trigger signal delay unit)
20c, 20d delay unit (output synchronization trigger signal delay unit)
20f, 20g delay unit (electrical pulse delay unit)
30a, 30b, 30d Pulse light output unit 32 Ultrasonic pulse output unit 34 Optical switch 40 Measuring unit 50 Moving unit

Claims (11)

  1.  超音波パルスを出力する超音波パルス出力部と、
     波長が異なるパルス光を出力する複数のパルス光出力部と、
     前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御部と、
     前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定部と、
     を備えた光超音波測定装置。
    An ultrasonic pulse output unit that outputs an ultrasonic pulse;
    A plurality of pulsed light output units that output pulsed light having different wavelengths;
    A pulse output time point control unit that controls a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights is output does not overlap each other When,
    A measuring unit that measures the measurement target based on a reflected wave of the ultrasonic pulse reflected on the measurement target and a photoacoustic wave generated on the measurement target by the pulse light;
    Optical ultrasonic measurement device equipped with.
  2.  請求項1に記載の光超音波測定装置であって、
     トリガ信号が、超音波パルス用トリガ信号および複数のパルス光用トリガ信号からなり、
     前記超音波パルス用トリガ信号が、前記超音波パルスを発生させるために、前記超音波パルス出力部に与えられ、
     前記パルス光用トリガ信号の各々が、前記パルス光を発生させるために、前記パルス光出力部の各々に与えられる、
     光超音波測定装置。
    The optical ultrasonic measurement device according to claim 1, wherein
    The trigger signal is composed of an ultrasonic pulse trigger signal and a plurality of pulse light trigger signals,
    The ultrasonic pulse trigger signal is applied to the ultrasonic pulse output unit to generate the ultrasonic pulse.
    Each of the pulse light trigger signals is provided to each of the pulse light output units to generate the pulse light.
    Optical ultrasonic measurement device.
  3.  請求項2に記載の光超音波測定装置であって、
     前記パルス出力時点制御部が、
     ある一つの前記トリガ信号を遅延させて、別の一つの前記トリガ信号とするトリガ信号遅延部、
     を有する光超音波測定装置。
    The optical ultrasonic measurement device according to claim 2, wherein
    The pulse output time point control unit
    A trigger signal delay unit that delays one of the trigger signals into another one of the trigger signals;
    Optical ultrasonic measurement device having.
  4.  請求項2に記載の光超音波測定装置であって、
     前記パルス出力時点制御部が、
     ある一つの前記パルス光出力部が前記パルス光を出力した時点に同期して出力する出力同期トリガ信号を遅延させて、ある一つの前記トリガ信号とする出力同期トリガ信号遅延部、
     を有する光超音波測定装置。
    The optical ultrasonic measurement device according to claim 2, wherein
    The pulse output time point control unit
    An output synchronization trigger signal delaying unit for delaying an output synchronization trigger signal output in synchronization with a point in time when one of the pulse light output units outputs the pulse light, and setting it as one certain trigger signal;
    Optical ultrasonic measurement device having.
  5.  請求項2に記載の光超音波測定装置であって、
     前記パルス出力時点制御部が、
     前記パルス光を光電変換した電気パルスを遅延させて、ある一つの前記トリガ信号とする電気パルス遅延部、
     を有する光超音波測定装置。
    The optical ultrasonic measurement device according to claim 2, wherein
    The pulse output time point control unit
    An electric pulse delay unit that delays an electric pulse obtained by photoelectrically converting the pulse light to form one certain trigger signal;
    Optical ultrasonic measurement device having.
  6.  請求項1に記載の光超音波測定装置であって、
     ある一つの前記パルス光出力部が、別の一つの前記パルス光出力部の出力する前記パルス光を受けて波長を変換して出力するものであり、
     別の一つの前記パルス光出力部の出力を、ある一つの前記パルス光出力部および前記測定対象のいずれに与えるかを切り替えることができる光スイッチ、
     を備えた光超音波測定装置。
    The optical ultrasonic measurement device according to claim 1, wherein
    One certain pulsed light output unit receives the pulsed light output from another one pulsed light output unit, converts the wavelength, and outputs the converted light.
    An optical switch capable of switching which one of the pulse light output unit and the measurement object to which the output of another one of the pulse light output units is given,
    Optical ultrasonic measurement device equipped with.
  7.  請求項1ないし6のいずれか一項に記載の光超音波測定装置であって、
     移動制御パルスを受けて、前記超音波パルスおよび前記パルス光が前記測定対象に与えられる位置を移動させる移動部を備え、
     前記パルス出力時点制御部が、前記移動制御パルス、前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記移動制御パルス、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御する、
     光超音波測定装置。
    The optical ultrasonic measurement device according to any one of claims 1 to 6, wherein
    A moving unit configured to move a position at which the ultrasonic pulse and the pulsed light are given to the measurement target in response to a movement control pulse;
    The movement control pulse, the ultrasonic pulse, and the plurality of ultrasonic light pulses may be controlled so that the time during which each of the movement control pulse, the ultrasonic pulse, and the plurality of pulsed lights is output does not overlap each other. Control when each of the pulsed lights is output,
    Optical ultrasonic measurement device.
  8.  請求項7に記載の光超音波測定装置であって、
     前記移動制御パルスの立下りよりも後で、さらに別の前記超音波パルスおよび複数の前記パルス光の各々が出力される、
     光超音波測定装置。
    The optical ultrasonic measurement device according to claim 7, wherein
    After the falling of the movement control pulse, each of the further ultrasonic pulse and the plurality of pulsed lights are output,
    Optical ultrasonic measurement device.
  9.  超音波パルスを出力する超音波パルス出力部と、波長が異なるパルス光を出力する複数のパルス光出力部とを有する光超音波測定装置による光超音波測定方法であって、
     前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御工程と、
     前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定工程と、
     を備えた光超音波測定方法。
    An optical ultrasonic measurement method by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths,
    A pulse output time point control step of controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights are output does not overlap each other When,
    Measuring the object to be measured based on a reflected wave of the ultrasonic pulse reflected on the object of measurement and a photoacoustic wave generated on the object of measurement by the pulsed light;
    Optical ultrasonic measurement method equipped with.
  10.  超音波パルスを出力する超音波パルス出力部と、波長が異なるパルス光を出力する複数のパルス光出力部とを有する光超音波測定装置による光超音波測定処理をコンピュータに実行させるためのプログラムであって、
     前記光超音波測定処理が、
     前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御工程と、
     前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定工程と、
     を備えたプログラム。
    A program for causing a computer to execute an optical ultrasonic measurement process by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths. There,
    The optical ultrasonic measurement process
    A pulse output time point control step of controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights are output does not overlap each other When,
    Measuring the object to be measured based on a reflected wave of the ultrasonic pulse reflected on the object of measurement and a photoacoustic wave generated on the object of measurement by the pulsed light;
    Program with.
  11.  超音波パルスを出力する超音波パルス出力部と、波長が異なるパルス光を出力する複数のパルス光出力部とを有する光超音波測定装置による光超音波測定処理をコンピュータに実行させるためのプログラムを記録したコンピュータによって読み取り可能な記録媒体であって、
     前記光超音波測定処理が、
     前記超音波パルスおよび複数の前記パルス光の各々が出力されている時間が互いに重複しないように、前記超音波パルスおよび複数の前記パルス光の各々が出力される時点を制御するパルス出力時点制御工程と、
     前記超音波パルスが測定対象において反射された反射波および前記パルス光により前記測定対象において発生した光音響波に基づき前記測定対象を測定する測定工程と、
     を備えた記録媒体。
    A program for causing a computer to execute an optical ultrasonic measurement process by an optical ultrasonic measurement apparatus having an ultrasonic pulse output unit that outputs an ultrasonic pulse and a plurality of pulsed light output units that output pulsed light having different wavelengths A computer readable recording medium recorded thereon, the recording medium comprising:
    The optical ultrasonic measurement process
    A pulse output time point control step of controlling a time point at which each of the ultrasonic pulse and the plurality of pulsed lights is output so that the time during which each of the ultrasonic pulse and the plurality of pulsed lights are output does not overlap each other When,
    Measuring the object to be measured based on a reflected wave of the ultrasonic pulse reflected on the object of measurement and a photoacoustic wave generated on the object of measurement by the pulsed light;
    Recording medium provided with
PCT/JP2018/039411 2017-12-07 2018-10-24 Light ultrasound measurement device, method, program, and storage medium WO2019111568A1 (en)

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