WO2019098742A2 - Dispositif stéréotaxique, système stéréotaxique et procédé d'enregistrement utilisant un système stéréotaxique - Google Patents

Dispositif stéréotaxique, système stéréotaxique et procédé d'enregistrement utilisant un système stéréotaxique Download PDF

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Publication number
WO2019098742A2
WO2019098742A2 PCT/KR2018/014082 KR2018014082W WO2019098742A2 WO 2019098742 A2 WO2019098742 A2 WO 2019098742A2 KR 2018014082 W KR2018014082 W KR 2018014082W WO 2019098742 A2 WO2019098742 A2 WO 2019098742A2
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WIPO (PCT)
Prior art keywords
marker
probe
side plates
image
disposed
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PCT/KR2018/014082
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English (en)
Korean (ko)
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WO2019098742A3 (fr
Inventor
김형욱
권영식
Original Assignee
주식회사 고영테크놀러지
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Publication of WO2019098742A2 publication Critical patent/WO2019098742A2/fr
Publication of WO2019098742A3 publication Critical patent/WO2019098742A3/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B2090/364—Correlation of different images or relation of image positions in respect to the body
    • A61B2090/365—Correlation of different images or relation of image positions in respect to the body augmented reality, i.e. correlating a live optical image with another image

Definitions

  • the present disclosure relates to a matching method that utilizes a stereotactic system, a stereotactic system, and a stereotactic system.
  • the present invention has been derived from the research carried out as part of the support of the WC300 project technology development by the Small and Medium Business Administration [assignment: S2482672, title: development of navigation fusion fusion head and neck surgery robot system with matching accuracy of 1mm or less].
  • Stereotactic surgery is a procedure in which a position of a specific region (for example, a lesion region of the brain) in a subject such as a patient is determined using a three-dimensional coordinate system, and a series of processes It says.
  • Stereotactic surgery has the advantage of minimizing the invasion of areas of the subject except the lesion area, compared to the conventional surgical methods.
  • the image of the site is acquired by a radiographic apparatus, a computed tomography (CT) apparatus, (Magnetic Resonance Imaging) apparatus, and the like.
  • CT computed tomography
  • Magnetic Resonance Imaging Magnetic Resonance Imaging
  • the image space coordinates in the image captured by the imaging apparatus are converted into local space coordinates in the local area such as the operating room It needs to be matched. If the spatial coordinates are not precisely matched to the local spatial coordinates, an error may occur between the lesion site at the imaging stage and the lesion site at the surgical stage. Such an error makes it impossible to perform an operation for an accurate lesion site. In particular, when very high precision is required, such as brain surgery, this error can lead to fatal brain damage to the patient.
  • the present disclosure provides a matching method using a stereotactic apparatus, a stereotactic system, and a stereotactic system configured to match an image space coordinate to a local spatial coordinate through a special marker.
  • a stereotactic apparatus includes a stereotactic frame configured to receive a target object and having a plurality of side plates and a plurality of side plates disposed on two or more side plates of the plurality of side plates so as to be displayed on an image captured with the object And may include three or more minor markers.
  • One of the special marker and the probe may be configured to receive the other one so that the local spatial coordinates of the special marker can be detected by the probe.
  • the secondary marker may have a marker pivot point corresponding to the local spatial coordinates.
  • the probe may have a probe pivot point detectable by the position and orientation of the probe. When the marker pivot point and the probe pivot point are placed at the same position, the local spatial coordinates of the secondary marker are detectable.
  • the minor marker may be provided with a recess for guiding one end of the probe so that the marker pivot point and the probe pivot point are located at the same position with respect to each other.
  • the probes may be configured to be rotatable in the recesses in contact with the recesses.
  • the opening cross-sectional area of the recess can become narrower from the outside to the inside of the minor marker.
  • the secondary marker may comprise a metal.
  • the minor marker may comprise a magnetic material.
  • each of the secondary markers includes a chamber that contains a liquid containing hydrogen, and a recess that is spaced from the chamber and guides one end of the probe so that the probe pivot point and the marker pivot point are located at the same position .
  • the recesses may be spaced apart from the chamber in a direction perpendicular to the side plate on which the minor marker is disposed.
  • the minor marker includes a first housing having a recess and a first cavity forming a part of the chamber, and a second cavity coupled to the first housing and configured to form a remaining portion of the chamber And a second housing.
  • the orientation apparatus may further comprise an indicator disposed on each of the at least two side plates of the plurality of side plates so as to be displayed on the image.
  • the indicator may be disposed on each of the plurality of side plates facing each other.
  • the minor marker may be disposed on each of the side plates facing each other on which the indicators of the plurality of side plates are disposed.
  • the indicator comprises a first rod, a second rod disposed parallel to the first rod, and a second rod connected to one end of the first rod and the other end of the second rod, And a third rod disposed obliquely to the rod.
  • a stereotactic apparatus includes a stereotactic frame configured to receive a target object and having a plurality of side plates and disposed on each of at least two side plates of the plurality of side plates so as to be displayed on an image taken with the target object And one or more minor markers disposed on at least one side plate of the side plates on which the indicators are arranged so as to be displayed on the image.
  • a stereotactic system includes a stereotactic frame configured to receive a target object and having a plurality of side plates, at least one of which is disposed on each of the plurality of side plates so as to be displayed on an image captured with the target object
  • a marker pivot point corresponding to the local spatial coordinates of the partial marker and a probe pivot point detectable by the position and orientation of the probe are located at the same position
  • a processor configured to detect the local spatial coordinates of the secondary marker when positioned in the image and to match the spatial spatial coordinates of the secondary marker displayed on the image to the local spatial coordinates of the secondary marker detected by the probe, . ≪ / RTI >
  • the stereotactic system may further include an imaging device that images an object and forms an image.
  • the orientation apparatus may further comprise an optical tracking device for detecting the position and orientation of the probe.
  • the probe may include a tip portion formed to have a hemispherical shape at one end.
  • the probe pivot point may be set to the center of curvature of the hemispherical tip.
  • a matching method is a method of matching image space coordinates to local space coordinates using the above-described orthogonal system.
  • the matching method includes the steps of capturing an image of a target object to be worn by the stereoscopic apparatus, detecting the image space coordinates of the minor marker displayed on the acquired image, and arranging the marker pivot point and the probe pivot point at the same position Detecting the local spatial coordinates of the secondary marker by the probe when the local spatial coordinates are coincident with each other, and matching the spatial spatial coordinates to local spatial coordinates.
  • detecting the local spatial coordinates of the minor marker comprises: receiving the probe in the minor marker; detecting the position and orientation of the probe; and detecting the position and orientation of the probe based on the position and orientation of the probe. And determining the local spatial coordinates of the secondary marker.
  • a matching system including at least one frame arranged to receive a target object and having a plurality of side plates, at least one of which is disposed on each of the plurality of side plates so as to be displayed on an image taken with the target,
  • An optical tracking device configured to image at least a part of a pattern formed on the incidental marker to detect local spatial coordinates of the incidental marker; And to match the spatial spatial coordinates of the secondary spatial marker to the local spatial spatial coordinates of the secondary spatial spatial domain detected by the optical tracking device.
  • the matching method using the stereotactic apparatus, the stereotactic system, and the stereotactic system is configured so that the local spatial coordinates of the incidental marker can be detected by the probe, thereby accurately and easily matching the spatial spatial coordinates to the local spatial coordinates .
  • This accurate matching can improve the accuracy of the stereotactic surgery.
  • Figure 1 is a perspective view of a stereotactic device according to one embodiment of the present disclosure
  • Figure 2 shows an embodiment of an indicator disposed on the first side plate.
  • Fig. 3 shows another embodiment of the indicator arranged on the first side plate.
  • Fig. 4 shows another embodiment of the indicator arranged on the first side plate.
  • Figure 5 shows another embodiment of an indicator disposed on the first side plate.
  • FIG. 6 is a schematic view showing an indicator, a special marker, and a probe.
  • FIG. 7 is a perspective view showing the relative marker shown in FIG. 1; FIG.
  • FIG 8 is a schematic view showing a state in which the probe is spaced apart from the special marker.
  • FIG. 9 is a schematic view showing a state in which a probe is accommodated in a special marker.
  • FIG. 10 is a perspective view showing a stereotactic device according to another embodiment of the present disclosure.
  • FIG. 11 is a perspective view showing the special marker shown in FIG. 10; FIG.
  • FIG. 12 is an exploded perspective view showing the special marker shown in FIG.
  • 13 is a schematic view showing a state in which the probe is accommodated in the special marker.
  • Figure 14 is a block diagram illustrating a stereotactic system in accordance with one embodiment of the present disclosure.
  • FIG. 15 is a schematic view showing an example of use of the orientation system shown in Fig.
  • FIG. 16 is a perspective view showing the probe shown in FIG.
  • Figure 17 is a flow chart illustrating a matching method in accordance with one embodiment of the present disclosure.
  • FIG. 18 is a flowchart showing the local spatial coordinate detection step shown in Fig.
  • the expression " based on " is used to describe one or more factors affecting an action or an action of a decision, judgment, as described in the phrase or sentence in which the expression is contained, It does not exclude any additional factors that affect the decision, act of judgment or action.
  • Figure 1 is a perspective view of a stereotactic device according to one embodiment of the present disclosure
  • the stereotactic device 100 may include a stereotactic frame 120 and a fiducial marker 140.
  • the stereotactic apparatus 100 may further include a fixing device 110 for fixing the object and / or an indicator 130 for setting the relative position of the object.
  • the securing device 110 may be configured to immobilize the object immovably.
  • the fixing device 110 is fixed to a base such as a bed for imaging diagnosis or a surgical bed, and can fix the object continuously during imaging or surgery.
  • the coordinate system of the object can be determined based on the base.
  • the fixing device 110 may include a fixed frame 111, a plurality of fixing rods 112, and a plurality of fixing pins 113.
  • the stationary frame 111 serves to fix the stationary device 110 to the base and to couple the stationary frame 120 to the stationary device 110.
  • the fixed frame 111 is generally rectangular in shape with rounded corners, and a part of one side thereof may be opened to have a C-shape or a U-shape as a whole.
  • the fixed bar 112 may be disposed perpendicularly to the fixed frame 111 at each corner of the rectangle.
  • the fixing rod 112 is configured to be adjustable in height according to the size and shape of the object and can be coupled to the fixed frame 111 by fastening means such as bolts.
  • the plurality of fixing pins 113 may be installed at the upper end of each of the plurality of fixing bars 112 so as to be replaceable. A part of the distal end of the fixing pin 113 invades the object, and the object can be fixed.
  • the fixing pin 113 can be configured to be adjustable in length depending on the size and shape of the object.
  • the fixing pins 113 are provided in a plurality of types so as to have various lengths and diameters, and may be appropriately selected according to the size and shape of the object to be installed in the fixed bar 112.
  • the orienting frame 120 may include a plurality of side plates and a plurality of connecting members, and may be configured to receive the objects inside the side plates and the connecting members in a state where the side plates and the connecting members are engaged.
  • the stationary frame 120 may have a roughly rectangular parallelepiped shape in which the surface on which the stationary frame 111 is disposed is opened.
  • the stationary frame 120 may be removably coupled to the stationary frame 111 of the stationary device 110.
  • the object may pass through the stationary frame 111 and be located inside the stationary frame 120.
  • the stereotactic frame 120 continues to be coupled to the fixture 110 in the imaging phase and may be detached from the fixture 110 after imaging.
  • the stereotactic frame 120 may be coupled to the fixation device 110 in a surgical step and may be detached from the fixation device 110 immediately prior to the start of surgery. That is, the stereotactic frame 120 is separated from the fixing device 110 during the operation.
  • the plurality of side plates may be formed of the first to fifth side plates 121a, 121b, 121c, 121d, and 121e.
  • each of the first to fifth side plates 121a to 121e may have a substantially rectangular plate shape.
  • the first to fifth side plates 121a to 121e may be made of a non-metallic material (for example, a plastic material) so as not to be displayed on the CT image when the stereotactic device 100 is used for CT imaging in the imaging step have.
  • One side of each of the first to fourth side plates 121a to 121d among the side plates of the orthogonal frame 120 may be coupled to the fixed frame 111.
  • the fifth side plate 121e is disposed to face the fixed frame 111 with respect to the first to fourth side plates 121a to 121d so that the first to fourth side plates 121a to 121d To the opposite side.
  • the plurality of connecting members may be composed of first to eighth connecting members 122a, 122b, 122c, 122d, 122e, 122f, 122g, 122h.
  • the first to eighth connecting members 122a to 122h can be engaged with two adjacent side plates by fastening means such as bolts.
  • the first to eighth connecting members 122a to 122h and the fastening means are made of a non-metallic material (for example, a plastic material) ≪ / RTI >
  • the first to fourth connecting members 122a to 122d may be configured to couple the side plates to each other between two adjacent side plates of the first to fourth side plates 121a to 121d.
  • the first connection member 122a connects the first side plate 121a and the second side plate 121b
  • the second connection member 122b connects the second side plate 121b and the third side plate 121b
  • the third connecting member 122c connects the third side plate 121c and the fourth side plate 121d
  • the fourth connecting member 122d connects the fourth side plate 121d
  • the first side plate 121a the first side plate 121a.
  • the fifth to eighth connecting members 122e to 122h are formed so as to join the fifth side plate 121e and the first to fourth side plates 121a to 121d to each other at each side of the fifth side plate 121e Lt; / RTI >
  • the fifth connecting member 122e connects the first side plate 121a and the fifth side plate 121e
  • the sixth connecting member 122f connects the second side plate 121b and the fifth side plate 121b
  • the seventh connecting member 122g connects the third side plate 121c and the fifth side plate 121e
  • the eighth connecting member 122h connects the fourth side plate 121d
  • the fifth side plate 121e is formed so as to join the fifth side plate 121e and the first to fourth side plates 121a to 121d to each other at each side of the fifth side plate 121e Lt; / RTI >
  • the fifth connecting member 122e connects the first side plate 121a and the fifth side plate 121e
  • An indicator 130 may be disposed on each of at least two side plates of the plurality of side plates of the orienting frame 120. 1, the indicator 130 is disposed on each of the first to fifth side plates 121a to 121e. However, the present invention is not limited thereto, and two or more of the side plates 121a to 121e, An indicator 130 may be disposed. For example, the indicator 130 may be disposed on each of the two side plates facing each other among the first to fifth side plates 121a and 121e. The indicator 130 is displayed on a plurality of tomographic images and serves to represent the relative positional relationship of the object. In the present embodiment, the indicator 130 is disposed on each of the first to fifth side plates 121a to 121e. In the following description, the indicator 130 disposed on the first side plate 121a has a configuration centering on the indicator 130 Will be described in detail.
  • Fig. 2 shows an indicator installed on the first side plate.
  • the indicator 130 may include a first rod 131, a second rod 132, and a third rod 133.
  • the first to third rods 131, 132, and 133 may be made of an imageable material that can be displayed on a CT image or an MRI image, or may have a tubular shape to receive an imageable material.
  • the imageable material of the indicator for CT may comprise metal
  • the imageable material of the MRI indicator may comprise a liquid (e.g., water) comprising hydrogen.
  • the second rod 132 may be disposed parallel to the first rod 131 at the first side plate 121a.
  • the third rod 133 may be connected to one end of the first rod 131 and the other end of the second rod 132 and be inclined with respect to the first rod 131 and the second rod 132.
  • the first to third rods 131, 132, and 133 connected in this manner may be arranged in an N-shape or a Z-shape as a whole.
  • Figs. 3 to 5 show various embodiments of the indicator installed on the first side plate.
  • the indicator 130a includes a first rod 131, a second rod 132, a third rod 133, and a fourth rod 134 can do.
  • the first to third rods 131, 132, and 133 may be configured in the same manner as the indicator 130 according to the embodiment shown in FIG.
  • the fourth rod 134 may be connected to the other end of the first rod 131 and the other end of the second rod 132 and may be disposed perpendicular to the first rod 131 and the second rod 132.
  • the first rod 131, the second rod 132, and the fourth rod 134 may be arranged in a C-shape.
  • the indicator 130b includes a first rod 131, a second rod 132, a third rod 133, a fourth rod 134, And a fifth rod 135.
  • the first to fourth rods 131, 132, 133, and 134 may be configured in the same manner as the indicator 130a according to the embodiment shown in FIG.
  • the fifth rod 135 may be connected to one end of the first rod 131 and one end of the second rod 132 and may be disposed perpendicular to the first rod 131 and the second rod 132.
  • the first rod 131, the second rod 132, the fourth rod 134, and the fifth rod 135 may be arranged in a square shape.
  • the indicator 130c includes a first rod 131, a second rod 132, a third rod 133, and a sixth rod 136 .
  • the first to third rods 131, 132, and 133 may be configured in the same manner as the indicator 130 according to the embodiment shown in FIG.
  • the sixth rod 136 may be disposed at an intermediate position between the first rod 131 and the second rod 132 so as to be parallel to the first rod 131 and the second rod 132, respectively.
  • the sixth rod 136 may be arranged to intersect with the third rod 133.
  • the minor marker 140 may be disposed on at least two side plates of the plurality of side plates so that the minor marker 140 is displayed on an image captured with the object, and three or more of them may be disposed. Since the minor marker 140 is displayed on the image, the image space coordinates can be identified in the image space.
  • the image space refers to a three-dimensional region or space within the image that is captured by the object and the special marker 140, and the image space coordinates may refer to coordinates on the image space.
  • the local space means an actual physical space or a three-dimensional region such as an operating room in which an operation for an object is performed, and the local spatial coordinates may mean coordinates on the local space.
  • two or more minor marker 140 may be disposed on one side plate of the orientation frame 120.
  • the secondary marker 140 may be releasably coupled to one side plate of the stationary frame 120.
  • the minor marker 140 may be disposed so as not to overlap with the indicator 130 on one side plate of the frame 120.
  • the secondary marker 140 may include a metallic material so that it can be displayed on the CT image in the imaging step.
  • At least one minor marker 140 is positioned between the first through fifth side plates 121a through 121e Respectively.
  • one minor marker 140 may be disposed on one side plate, and one minor marker 140 may be disposed on another side plate facing one side plate.
  • one minor marker 140 is disposed on one side plate, one minor marker 140 is disposed on the other side plate adjacent to one side plate, The markers 140 may be disposed on one side plate and another side plate adjacent to the other side plate.
  • the configuration will be described in detail with reference to one of the special markers 140 disposed on the first side plate 121a.
  • the minor marker 140 is arranged such that at least one of the minor markers 140 is disposed on the side plate on which the indicator 130 is disposed .
  • the secondary marker 140 may be disposed on each of two side plates facing each other on which the indicator 130 of the first through fifth side plates 121a through 121e is disposed.
  • at least one minor marker 140 is disposed on one side plate in which an indicator 130 is disposed, and at least one minor marker 140 is positioned facing one of the side plates and an indicator 130 May be disposed on the other side plate on which the first and second side plates are disposed.
  • FIG. 6 is a schematic view showing an indicator, a special marker, and a probe.
  • a first reference line L1 in the left and right direction.
  • a first intersection P1 at which the first reference line L1 crosses the first rod 131 and a first intersection P1 at which the first reference line L1 intersects the second reference line L1 A second intersection point P2 intersecting with the rod 132 and a third intersection point P3 intersecting the third rod 133 with the first reference line L1 may be displayed.
  • a fourth intersection P4 where the second reference line L2 crosses the first rod 131 A fifth intersection P5 at which the reference line L2 intersects the second rod 132 and a sixth intersection P6 at which the second reference line L2 intersects the third rod 133 can be displayed.
  • the seventh intersection P7 where the third reference line L3 intersects with the first rod 131 An eighth intersection P8 at which the reference line L3 intersects the second rod 132 and a ninth intersection P9 at which the third reference line L3 intersects the third rod 133 can be displayed.
  • the distance d1 between the first intersection P1 and the third intersection P3 along the first reference line L1 is the distance between the fourth intersection P4 along the second reference line L2, Differs from the distance d3 between the seventh intersection P7 and the ninth intersection P9 along the third reference line L3.
  • the relative positional relationship of the tomographic images can be determined based on the positional relationship of the respective intersection points displayed on the tomographic image along the plurality of reference lines parallel to the first to third reference lines L1 to L3.
  • a plurality of tomographic images in which the indicator 130 and the object are displayed can be converted into a three-dimensional image of the object by being aligned based on the relative positional relationship between the indicator 130 and the object.
  • the spatial coordinates of the special marker 140 can be obtained.
  • the local spatial coordinates of the secondary marker 140 can be obtained by accommodating the probe 321 in the secondary marker 140. And, by matching the coordinates of the image space with the coordinates of the local space, the position on the local space with respect to the lesion portion of the object can be determined. As a result, the accuracy of the stereotactic surgery can be improved.
  • the secondary marker 140 may be configured to be identifiable by an optical tracking device 322 (see FIG. 13) described below. For example, a certain pattern is formed on the minor marker 140, and the optical tracking device 322 captures a part or all of the pattern formed on the minor marker 140, Local spatial coordinates can be identified. The spatial coordinates of the spatial marker 140 may be matched to the local spatial coordinates of the secondary marker 140 identified by the optical tracking device 322. [
  • FIG. 7 is a perspective view showing a special marker disposed on the first side plate.
  • 8 is a schematic view showing a state in which the probe is spaced apart from the special marker.
  • the secondary markers 140 may be configured to accommodate the probes 321 such that the local spatial coordinates of the secondary markers 140 are detectable by the probes 321.
  • the secondary marker 140 may have a marker pivot point MP corresponding to the spatial and local spatial coordinates of the secondary marker 140.
  • the marker pivot point MP may be a predetermined point to represent the local spatial coordinates of the partial marker 140.
  • the marker pivot point MP may be set to the center point or the center coordinate of the incidental marker 140.
  • the probe 321 may have a probe pivot point PP detectable by the position and attitude of the probe 321.
  • the probe pivot point PP may be set to the center of curvature or the center of curvature of the tip portion 321a of the probe 321 described later.
  • the shape of the secondary marker 140 may be spherical or similar in shape, but is not limited thereto.
  • a concave portion 141 for guiding one end of the probe 321 may be formed in the minor marker 140 so that the marker pivot point MP and the probe pivot point PP are disposed at the same position.
  • the probe 321 can be guided by the recess 141 so that the user can easily place the marker pivot point MP and the probe pivot point PP at the same position with respect to each other.
  • the probe 321 may be configured to be pivotable or pivotable in the recess 141 in contact with the recess 141. [
  • the concave portion 141 and the probe 321 are arranged so that the marker pivot point MP and the probe pivot point PP are disposed at the same position with respect to each other, Can easily be detected.
  • FIG. 9 is a schematic view showing a state in which a probe is accommodated in a special marker.
  • the concave portion 141 may be formed such that the cross-sectional area of the opening of the concave portion 141 becomes narrower from the outer side to the inner side of the secondary marker 140.
  • the concave portion 141 may have a conical shape, a hemispherical shape, or a polygonal shape. Accordingly, one end of the probe 321 can be guided to the inside of the special marker 140 along the inclined corner or curved surface of the concave portion 141.
  • the probe pivot point MP of the secondary marker 140 and the probe pivot point MP of the probe 321 are held in the concave portion 141 of the secondary marker 140,
  • the probe pivot points PP may be disposed at the same position with respect to each other. Therefore, even if the probe 321 pivots at a predetermined angle with respect to the first side plate 121a in the concave portion 141 of the secondary marker 140, the pivot point of the secondary marker 140 MP and the pivot point PP of the probe 321, respectively.
  • the pivot point MP of the secondary marker 140 can be easily and accurately detected by detecting the pivot point PP of the probe 321 while the probe 321 is accommodated in the recess 141.
  • the user can recognize the position of the relative marker 140 by locating the tip portion 321a of the probe 321 in the concave portion 141 of the relative marker 140 irrespective of the position in which the probe 321 is received,
  • the spatial coordinates can be detected easily and accurately.
  • FIG. 10 is a perspective view showing a stereotactic device according to another embodiment of the present disclosure.
  • the stereotactic device 200 may include a stationary frame 120 and a special marker 240.
  • the stereotactic apparatus 200 according to another embodiment of the present disclosure may further include a fixing device 110 for fixing the object and / or an indicator 130 for setting the relative position of the object.
  • a fixing device 110 for fixing the object and / or an indicator 130 for setting the relative position of the object.
  • components having the same reference numerals as those of the stereophotographing apparatus 100 according to the embodiment shown in FIG. 1 have the same configuration, and a detailed description thereof will be omitted do.
  • FIG. 11 is a perspective view showing a detailed configuration of the special marker shown in FIG. 12 is an exploded perspective view showing a detailed configuration of the special marker shown in FIG. 13 is a schematic view showing a state in which the probe is accommodated in the special marker.
  • the chamber 241 and the recess 242 may be formed in the secondary marker 240.
  • the chamber 241 may have a spherical shape, but is not limited thereto and may have any shape capable of receiving a liquid.
  • a liquid containing hydrogen e.g., water
  • the chamber 241 may include a first cavity 241a constituting a part of the chamber 241 and a second cavity 241b constituting the remaining part of the chamber 241 .
  • the first cavity 241a and the second cavity 241b may each have a hemispherical shape. Accordingly, the first cavity 241a and the second cavity 241b may be combined with each other so that the chamber 241 may be a completely spherical container.
  • the secondary marker 240 may include a first housing 243, a second housing 244, and a seal ring 245.
  • the first cavity 241a and the concave portion 242 may be formed in the first housing 243 and the second cavity 241b may be formed in the second housing 244.
  • the second housing 244 can be detachably coupled to the first housing 243.
  • the first housing 243 can be screwed into the second housing 244.
  • the seal ring 245 is disposed between the first housing 243 and the second housing 244 and serves to seal between the first housing 243 and the second housing 244.
  • the minor marker 240 may be coupled to at least one of the first to fifth side plates 121a to 121e.
  • the second housing 244 can be releasably coupled to each side plate by screwing. Therefore, when the liquid in the chamber 241 evaporates due to the long use of the secondary marker 240, the new secondary marker 240 can be easily replaced.
  • the concave portion 242 is spaced from the chamber 241 and guides one end of the probe 321 so that the probe pivot point PP and the marker pivot point MP are disposed at the same position with respect to each other Lt; / RTI >
  • the marker pivot point MP of the secondary marker 240 may mean the center coordinates of the spherical chamber 241.
  • the concave portion 242 can be formed such that the opening cross sectional area of the concave portion 242 becomes narrower from the outside to the inside of the special marker 240.
  • the concave portion 242 may have a conical shape, a hemispherical shape, or a polygonal shape.
  • one end of the probe 321 can be guided inwardly of the secondary marker 240 along the inclined edge or curved surface of the recess 242.
  • the pivot point MP of the secondary marker 240 and the probe 321 of the probe 321 are moved in the state in which the probe 321 is completely received in the concave portion 242 of the secondary marker 240,
  • the pivot points PP can be disposed at the same position with respect to each other.
  • the local spatial coordinates of the secondary marker 240 can be set to be spaced from the marker pivot point MP by a predetermined distance d while the probe 321 is accommodated in the recess 242.
  • the concave portion 242 may be spaced apart from the chamber 241 in a direction perpendicular to the first side plate 121a on which the special marker 240 is disposed.
  • the position and position of the probe 321 can be detected by optical tracking while the position of the probe pivot point PP of the probe 321 is detected by the probe 321 The position, and the geometric structure of the robot.
  • the position of the probe pivot point PP of the probe 321 is determined, the local spatial coordinates of the special marker 240 spaced apart from the position by the distance d can be determined.
  • the concave portion 141 of the special marker 140 is provided at one end of the probe 321, and the tip portion 321a of the probe 321 is provided at one end of the probe 321.
  • Or may be provided in the secondary marker 140.
  • a recess 242 of the secondary marker 240 may be provided at one end of the probe 321 and a tip 321a of the probe 321 may be provided at the secondary marker 240.
  • Figure 14 is a block diagram illustrating a stereotactic system in accordance with one embodiment of the present disclosure.
  • 15 is a schematic view showing an example of use of the orientation system shown in Fig.
  • the orientation system 300 may include a positioning apparatus 100 or 200, a processing apparatus 310, and a probe 321.
  • the orientation apparatus 100 or 200 according to this embodiment is the same as the orientation apparatus 100 or 200 according to the embodiments shown in FIGS. 1 to 13, and thus a detailed description thereof will be omitted.
  • the processing device 310 is configured to match the spatial spatial coordinates of the secondary markers 140 or 240 displayed in the image to the local spatial coordinates of the secondary markers 140 or 240 detected by the probe 321 .
  • the processing unit 310 may be configured to transmit and receive electrical signals to the probe 321 and the imaging device 330 via wire or wireless.
  • the probe 321 may include a probe 321 that is receptive to the minor marker 140 or 240.
  • the probe 321 is positioned such that the marker pivot point MP corresponding to the local spatial coordinates of the secondary marker 140 or 240 and the probe pivot point PP detectable by the position and attitude of the probe 321 are at the same position And may be configured to detect the local spatial coordinates of the minor marker 140 or 240 when placed.
  • FIG. 16 is a perspective view showing a detailed configuration of the probe shown in Fig.
  • the probe 321 may include a hemispherical or rounded tip 321a and an optical tracking marker 321b disposed on the opposite side of the tip 321a.
  • the optical tracking markers 321b may include a plurality of spherical shapes or patterns so that they can be detected by the optical tracking device 322.
  • the optical tracking device 322 may be composed of an image forming apparatus for capturing the position and posture of the optical tracking marker 321b and a processing device for determining the position of the leading end portion 321a from data obtained from the image forming apparatus.
  • the optical tracking device 322 is not electrically connected to the processing unit 310 of the above-described orthogonalization system 300 without the separate processing unit and is connected to the tip portion 321a by the processing unit 310. [ As shown in FIG.
  • the processing device 310 also matches the spatial coordinates of the secondary markers 140 or 240 to the local spatial coordinate system of the secondary markers 140 or 240.
  • the tip portion 321a of the probe 321 in the concave portion 141 or 242 When the user accommodates the tip portion 321a of the probe 321 in the concave portion 141 or 242, the tip portion 321a is guided along the concave portion 141 or 242,
  • the pivot points PP can be accurately positioned at the same position with respect to each other.
  • the accuracy of the stereotactic surgery can be improved.
  • the stereotactic system 300 may further include an imaging device 330 that images an object and forms an image.
  • the object and the differential marker 140 or 240 can be picked up through the imaging apparatus 330 and displayed on the image in a state where the orientation apparatus 100 or 200 is mounted on the object.
  • the imaging diagnostic device 330 may include an X-ray imaging device, a CT device, or an MRI device.
  • Figure 17 is a flow chart illustrating a matching method in accordance with one embodiment of the present disclosure.
  • the matching method 400 includes an image acquisition step S410, an image space coordinate detection step S420, a local space coordinate detection step S430, , And matching the image space coordinates and the local space coordinates (S440).
  • the stereotactic device 100 or 200 Before the image acquisition step S410, the stereotactic device 100 or 200 according to the embodiment shown in Figs. 1 to 13 is worn on the object, and the object and the stereotactic device 100 or 200 can be fixed to the base .
  • an object worn by the orientation apparatus (100 or 200) may be imaged through the imaging apparatus (330) to obtain an image. Since the stereotactic apparatus 100 or 200 having the indicator 120 and the special marker 140 or 240 on the object is worn on the object, the image obtained in the image acquisition step S410 includes the indicator 120, (140 or 240) may be displayed together.
  • the image obtained in the image acquiring step S410 may include an X-ray image, a CT image, or an MRI image.
  • the image space coordinates corresponding to the marker pivot point MP of the special marker 140 or 240 on the image space in the obtained image may be detected.
  • the imaging device 330 may identify the position of the secondary marker 140 or 240 in the image space as the spatial coordinate have.
  • FIG. 18 is a flowchart showing the local space coordinate detection step shown in Fig.
  • the local spatial coordinate detection step S430 local spatial coordinates corresponding to the pivot point (MP) of the special marker (140 or 240) in the local space may be detected.
  • the local spatial coordinate detection step S430 includes a step S431 of receiving the probe in the special marker, a step S432 of detecting the position and attitude of the probe, (S433).
  • the optical tracking device 322 moves toward the posture of the probe 321 and the tip portion 321a, And the processing apparatus 310 detects the position of the tip 321a of the probe 321 and the position of the tip 321a of the probe 321 in consideration of the geometry of the probe 321 and the tip 321a.
  • the local spatial coordinates of the extremal marker 140 or 240 can be detected.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

La présente invention comprend : un bâti stéréotaxique formé pour recevoir un sujet et comprenant une pluralité de plaques latérales ; et au moins trois marqueurs de repère disposés sur au moins deux plaques latérales parmi la pluralité de plaques latérales de façon à être affichés sur une image capturée conjointement avec le sujet. Chacun des marqueurs de repère est conçu de sorte que l'un du marqueur de repère et d'une sonde puisse recevoir l'autre afin de détecter les coordonnées spatiales locales du marqueur de repère par la sonde.
PCT/KR2018/014082 2017-11-17 2018-11-16 Dispositif stéréotaxique, système stéréotaxique et procédé d'enregistrement utilisant un système stéréotaxique WO2019098742A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2017-0153811 2017-11-17
KR1020170153811A KR102079209B1 (ko) 2017-11-17 2017-11-17 정위 장치, 정위 시스템, 및 정위 시스템을 이용하는 정합 방법

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112656508A (zh) * 2020-12-18 2021-04-16 华科精准（北京）医疗科技有限公司 一种新型配准辅助装置
CN112656509A (zh) * 2020-12-18 2021-04-16 华科精准（北京）医疗科技有限公司 一种配准辅助装置

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KR102479203B1 (ko) * 2021-03-31 2022-12-19 경북대학교 산학협력단 혈관조영 가이드 인디케이터

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US20060281991A1 (en) * 2003-05-09 2006-12-14 Fitzpatrick J M Fiducial marker holder system for surgery
GB2428110A (en) * 2005-07-06 2007-01-17 Armstrong Healthcare Ltd A robot and method of registering a robot.
WO2009006935A1 (fr) * 2007-07-06 2009-01-15 Karolinska Institutet Innovations Ab Système de chirurgie stéréotaxique
JP6456924B2 (ja) * 2013-04-30 2019-01-23 シーダーズ−サイナイ メディカル センター 医療処置のための固定装置及び方法
US11090130B2 (en) * 2015-10-09 2021-08-17 Oregon State University Fiducial marker for computed tomography and magnetic resonance imaging

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112656508A (zh) * 2020-12-18 2021-04-16 华科精准（北京）医疗科技有限公司 一种新型配准辅助装置
CN112656509A (zh) * 2020-12-18 2021-04-16 华科精准（北京）医疗科技有限公司 一种配准辅助装置
CN112656509B (zh) * 2020-12-18 2023-09-22 华科精准（北京）医疗科技有限公司 一种配准辅助装置
CN112656508B (zh) * 2020-12-18 2023-09-26 华科精准（北京）医疗科技有限公司 一种新型配准辅助装置

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WO2019098742A3 (fr) 2019-07-18
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