WO2019093673A3 - 골질환 예방 또는 치료용 약학 조성물 - Google Patents

골질환 예방 또는 치료용 약학 조성물 Download PDF

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Publication number
WO2019093673A3
WO2019093673A3 PCT/KR2018/012305 KR2018012305W WO2019093673A3 WO 2019093673 A3 WO2019093673 A3 WO 2019093673A3 KR 2018012305 W KR2018012305 W KR 2018012305W WO 2019093673 A3 WO2019093673 A3 WO 2019093673A3
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WO
WIPO (PCT)
Prior art keywords
preventing
pharmaceutical composition
bone disease
treating bone
bone
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Application number
PCT/KR2018/012305
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English (en)
French (fr)
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WO2019093673A2 (ko
Inventor
김정렬
장규윤
박시형
강미애
Original Assignee
전북대학교 산학협력단
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Publication of WO2019093673A2 publication Critical patent/WO2019093673A2/ko
Publication of WO2019093673A3 publication Critical patent/WO2019093673A3/ko

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/306—Foods, ingredients or supplements having a functional effect on health having an effect on bone mass, e.g. osteoporosis prevention

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

본 발명은 골질환 예방 또는 치료용 약학 조성물에 관한 것으로, 구체적으로 골다공증(osteoporosis), 골연화증(osteomalacia), 골감소증(osteopenia), 골위축(bone atrophy), 골관절염(osteoarthritis), 치주염(periodontal disease)과 같은 골질환의 예방 또는 치료제나 기능성 식품의 첨가제로 새용될 수 있으며, 뼈의 형성 및 재생을 촉진하는 치료에 유용하게 활용될 수 있다는 이점을 가지고 있다.
PCT/KR2018/012305 2017-11-07 2018-10-18 골질환 예방 또는 치료용 약학 조성물 WO2019093673A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170147353A KR101992821B1 (ko) 2017-11-07 2017-11-07 골질환 예방 또는 치료용 약학 조성물
KR10-2017-0147353 2017-11-07

Publications (2)

Publication Number Publication Date
WO2019093673A2 WO2019093673A2 (ko) 2019-05-16
WO2019093673A3 true WO2019093673A3 (ko) 2019-06-27

Family

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Family Applications (1)

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PCT/KR2018/012305 WO2019093673A2 (ko) 2017-11-07 2018-10-18 골질환 예방 또는 치료용 약학 조성물

Country Status (2)

Country Link
KR (1) KR101992821B1 (ko)
WO (1) WO2019093673A2 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102466565B1 (ko) 2020-07-13 2022-11-10 전남대학교산학협력단 골질환 예방 또는 치료용 약학 조성물
KR102096793B1 (ko) 2019-07-15 2020-04-03 전남대학교 산학협력단 골질환의 예방 또는 치료용 의약 조성물
KR102014200B1 (ko) 2019-07-15 2019-08-26 전남대학교산학협력단 골질환의 예방 또는 치료용 의약 조성물
KR102466564B1 (ko) 2020-07-13 2022-11-10 전남대학교산학협력단 골질환 예방 또는 치료용 약학 조성물
WO2022085819A1 (ko) 2020-10-22 2022-04-28 (주)네오리젠바이오텍 골 형성 촉진용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100926417B1 (ko) 2007-01-29 2009-11-12 한올제약주식회사 Ｎ,ｎ―디메틸 이미도디카르본이미딕 디아미드의 초산염,그의 제조방법 및 그를 포함하는 약제학적 조성물
KR101761194B1 (ko) 2015-02-23 2017-07-25 원광대학교산학협력단 백작약 추출물을 함유하는 골대사성 질환 예방 및 치료용 조성물

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BAK,E. ETAL: "Abstract P123: Effect of metformin on osteoclastogenesis stimulated by bone resorption inducing factors", BONE, vol. 44, June 2009 (2009-06-01), pages S300, XP026136660 *
CORTIZO, A. M.: "Osteogenic actions of the anti-diabetic drug metformin on osteoblasts in culture", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 536, no. 1-2, 24 April 2006 (2006-04-24), pages 38 - 46, XP028029545, DOI: 10.1016/j.ejphar.2006.02.030 *
EE , Y. S.: "AMP kinase acts as a negative regulator of RANKL in the lifferentiation of osteoclasts", BONE, vol. 47, no. 5, 2010, pages 926 - 937, XP027406638 *
JANG, W.G. ET AL: "Metformin induces osteoblast differentiation via orphan nuclear receptor SHP-mediated transactivation of Runx2", BONE, vol. 48, no. 4, 2011, pages 885 - 893, XP028165837, DOI: 10.1016/j.bone.2010.12.003 *
JIANG, F.: "Experimental study on the effect of metformin on steroid - induced femoral head necrosis in mice", JOURNAL OF PRACTICAL MEDICINE, no. 20, 2014, pages 3210 - 3213 *
KANAZAWA, ETAL: "Metformin enhances the differentiation and mineralization of osteoblastic MC 3T3-E1 cells via AMP kinase activation as well as eNOS and BMP-2-expression", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 375, no. 3, 2008, pages 414 - 419, XP025398766 *

Also Published As

Publication number Publication date
KR101992821B1 (ko) 2019-06-25
WO2019093673A2 (ko) 2019-05-16
KR20190051547A (ko) 2019-05-15

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