WO2019076757A1 - Étiquette adhésive pour un récipient - Google Patents

Étiquette adhésive pour un récipient Download PDF

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Publication number
WO2019076757A1
WO2019076757A1 PCT/EP2018/077896 EP2018077896W WO2019076757A1 WO 2019076757 A1 WO2019076757 A1 WO 2019076757A1 EP 2018077896 W EP2018077896 W EP 2018077896W WO 2019076757 A1 WO2019076757 A1 WO 2019076757A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
sensor
adhesive label
signal
permanent magnet
Prior art date
Application number
PCT/EP2018/077896
Other languages
German (de)
English (en)
Inventor
Christian Ohl
David Bill
Philipp Troebner
Original Assignee
Robert Bosch Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch Gmbh filed Critical Robert Bosch Gmbh
Publication of WO2019076757A1 publication Critical patent/WO2019076757A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/1684—Monitoring, detecting, signalling or eliminating infusion flow anomalies by detecting the amount of infusate remaining, e.g. signalling end of infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/30—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by floats
    • G01F23/56—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by floats using elements rigidly fixed to, and rectilinearly moving with, the floats as transmission elements
    • G01F23/62—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by floats using elements rigidly fixed to, and rectilinearly moving with, the floats as transmission elements using magnetically actuated indicating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3317—Electromagnetic, inductive or dielectric measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3365—Rotational speed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3368—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3389—Continuous level detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3561—Range local, e.g. within room or hospital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31568—Means keeping track of the total dose administered, e.g. since the cartridge was inserted

Definitions

  • the invention relates to an adhesive label for a container, a container for interacting with the adhesive label and a device for interacting with the adhesive label. Likewise, the invention relates to a container with the attached adhesive label. Furthermore, the invention relates to a method for operating a sensor device for a container.
  • US 8,574,199 B2 describes a stick-shaped injection device as a medicament container.
  • the invention provides an adhesive label for a container having the features of claim 1, a container having the features of claim 4, a
  • a container having the features of claim 7 an apparatus having the features of claim 8 and a method of operating a sensor device for a container having the features of claim 9.
  • Adhesive label is attached.
  • the sensor device is correspondingly easy to remove even when the container is disposed of by removing the adhesive label.
  • Another advantage of the adhesive label according to the invention is the ability to dispense with an energy storage (such as a battery) for the
  • Another advantage of the adhesive label according to the invention is that it can also be dispensed with the equipment of the sensor device with its own evaluation. Instead, in the cooperating with the adhesive label of the invention external device
  • evaluation device formed in the external device can also be used elsewhere, it has a high degree of multi-functionality.
  • Sensor device a temperature-detecting device, an acceleration detecting means and / or a level detection means with respect to a level of a filled in the container with the attached adhesive label liquid, powdery and / or gel-like material.
  • the adhesive label for the container in which at least one permanent magnet is arranged so that a respective position and / or position of the respective permanent magnet in a reduction of the level of the liquid, powdery and / or gel material varies.
  • the fill level detection device of the adhesive label comprises at least one magnetic sensor, wherein, if the adhesive label is attached to the container and the sensor device is energized by the supply current, the at least one magnetic sensor is in each case designed such that in each case a field strength information with respect to a present at the respective magnetic sensor magnetic field strength of a magnetic field of the at least one permanent magnet of the magnetic sensor can be tapped off or tapped at the magnetic sensor, and the at least one sensor signal of the level detection device taking into account the at least one field strength Information can be output.
  • the at least one sensor signal of the level detection device in this case contains reliable information as to how much of the material is still in the container.
  • This information can be used in many ways. For example, it can then be examined by means of the evaluation device of the (external) device whether a patient treated by the container is within a predetermined treatment plan.
  • the advantages described above also cause a container for cooperation with the corresponding adhesive label, wherein the container is filled or filled with a liquid, powdery and / or gelatinous material, and wherein at least one permanent magnet is arranged in the container so that a respective position and / or position of the respective permanent magnet in a reduction of the level of the material in the container varies.
  • the container may comprise a linearly adjustable sealing element, which is designed such that, if the liquid,
  • the container may also include the linearly adjustable sealing element and a
  • Sealing element by means of a rotation of the threaded rod is linearly adjustable, and provided that the liquid, powdered and / or gelatinous material is filled in the container, the material by means of the linearly displaced sealing element at least partially graspbar from the container.
  • Permanent magnet of the container attached to the threaded rod or formed as at least part of the threaded rod.
  • the respective position of the at least one rotated permanent magnet can then be determined and used to determine the reliable
  • a container which is filled or filled with a liquid, powdery and / or gel-like material, and on which the
  • Receiving device by means of which the electromagnetic signal to the antenna device of the adhesive label can be emitted, and at least one of the antenna device of the adhesive label emitted sensor signal and / or information signal can be received.
  • the device may in particular be a mobile device, such as a mobile phone (cell phone, smartphone) or a alternative mobile device such as a tablet.
  • a mobile phone cell phone, smartphone
  • a alternative mobile device such as a tablet.
  • Figure 1 is a schematic representation of a first embodiment of the adhesive label, or of the container thus equipped.
  • FIG. 2a to 2f schematic total and partial representations of a second
  • 3a to 3c are schematic overall and partial views of a third
  • 4a to 4f are schematic diagrams for explaining a
  • Figures 5a and 5b are schematic partial representations of a container, which does not fall under the present invention.
  • Fig. 6 is a partial schematic illustration of a container which does not fall under the present invention. a schematic partial view of a container, which does not fall under the present invention; and schematic diagrams for explaining a
  • Fig. 1 shows a schematic representation of a first embodiment of the adhesive label, or a container equipped therewith.
  • the adhesive label 10 is fastened / fastened to a container 12, which is designed / inserted as a medicament container 12.
  • the container 12 is designed as a (stick-shaped) injection device 12 (pen for subcutaneous injection).
  • the adhesive label 10 is thus useful for, but not limited to, a versatile container type / type of medicament container.
  • the adhesive label 10 may be useful for any other type of container / type of medicament container which may be filled with a liquid, powdered and / or gelatinous material, e.g. a liquid, powdery and / or gel medicament, can be filled or filled.
  • the injection device 12 of FIG. 1 comprises a
  • Drug cartridge 16 a pen cover 18 with integrated injection mechanism, on which a selection mechanism 20 for adjusting a
  • Injection amount / output quantity is fixed, and a button 22 for injection.
  • the material cartridge 16 is filled or filled with the liquid, powdered and / or gel material / medicament, such as insulin.
  • the injection mechanism integrated in the pen shell 18 is designed to set the position determined by the selection mechanism 20 (and in a display window 24) upon pressing the button 22 out of the material cartridge 16 / the container 12. After emptying the material cartridge 16 formed as injection device 12 container 12 can either be disposed of completely or after replacing the
  • Material cartridge 16 are recycled.
  • the adhesive label 10 may also be referred to as a label 10.
  • on an adhesive side of the adhesive label 10 may be an adhesive layer (not shown) by means of which the adhesive label 10 on the container 12
  • the adhesive label 10 thus fulfills the usual functions of an adhesive label 10.
  • the adhesive label 10 may be formed in one or more layers.
  • the adhesive label 10 has an antenna device 26 arranged on and / or in the adhesive label 10.
  • a sensor device 28 is arranged on and / or in the adhesive label 10.
  • the antenna device 26 is designed in such a way and connected directly or indirectly to the sensor device 28 that when receiving an emitted from an (external) device 30 electromagnetic signal 32 through the antenna device 26 a
  • Antenna device 26 can be generated and output to the sensor device 28 is output / output.
  • the sensor device 28 powered by the supply current signal is designed to output at least one sensor signal.
  • the supply current signal generated by means of the antenna device 26 and output to the sensor device 28 is thus sufficient for a standard
  • Sensor device 28 / of the adhesive label 10 are omitted. It is quite sufficient if the sensor device 28 only upon receiving the emitted from the (external) device 30 electromagnetic signal 32nd activated / energized.
  • the at least one sensor signal output by the energized sensor device 28 and / or at least one information signal derived from the at least one sensor signal can be transmitted to the external device 30 by means of the antenna device 26. Preferably, therefore, for the evaluation of the at least one
  • Evaluation device can therefore be dispensed with.
  • the adhesive label 10 also an evaluation / a
  • the adhesive label 10 may also be formed with a display device / display,
  • the antenna device 26 may be formed with at least one planar-printed antenna, such as a pancake coil, a spiderweb coil and / or a conductor loop, and / or with at least one helix coil.
  • the sensor device 28 may comprise, for example, a level detection device with respect to a filling level of the liquid, powdery and / or gel material filled in the container 12 with the adhesive label attached thereto, a temperature detection device and / or an acceleration detection device.
  • Sensor signal / information signal can thus indicate, for example, the level of the container 12, a temperature of the container 12 and / or an acceleration of the container 12, or be convertible into at least one of the listed here.
  • Sensor signal / information signal can thus indicate, for example, the level of the container 12, a temperature of the container 12 and / or an acceleration of the container 12, or be convertible into at least one of the listed here.
  • the types of sensor listed here are only to be interpreted as examples, without any formability of the
  • the (external) device 30 may be, for example, a mobile device, in particular a mobile phone (mobile phone, smartphone) or a tablet computer.
  • the (external) device 30 may also be in the form of a permanently installed base station into which the container / injection device 12 is plugged, placed or otherwise attached, thus coupling both devices 12 and 30 in accordance with the technology described herein takes place.
  • the device 30 it is only necessary that the device 30 at least one transmitting and / or
  • Receiving device 34 by means of which the electromagnetic signal 32 to the antenna device 26 of the adhesive label 10 can be emitted
  • This design of the transmitting and / or receiving device 34 is by means of an easily executable
  • forming the device 30 for evaluating the at least one sensor signal / information signal is possible by means of a further programming step, which is likewise easy to carry out.
  • data and / or control commands from the device 30 to the adhesive label 10 can be sent.
  • identification markers and / or a security key may be interchangeable between the device 30 and the adhesive label 10.
  • Safety marker also be applied in another readable form on the adhesive label 10.
  • a 2-factor authentication may be needed and the adhesive label 10 may have an optical pattern, a bar code or the like which is additionally or exclusively captured by the device 30 (and possibly its camera).
  • FIG. 2a to 2f show schematic overall and partial views of a second embodiment of the adhesive label, or of the container equipped therewith.
  • Container / medicament container 12 have the features of the previously described embodiment.
  • the container 12 shown schematically in Fig. 2a also has at least one permanent magnet 40a, 40b, 42a and 42b, which in the container 12 (or the material cartridge 16) is arranged so that a respective position and / or position of the respective
  • Permanent magnets 40a, 40b, 42a and 42b in a reduction of
  • the sensor device 28 of the adhesive label 10 comprises a fill level detection device 44 with at least one magnetic sensor 46.
  • FIG. Detecting device 44 shown partially enlarged. It can be seen that the magnetic sensors 46 of the fill level detection device 44 are advantageously arranged in a row which is pushed along an injection direction 48 in which the liquid, powdery and / or gel material is forced out of the container 12 (or the material cartridge 16) , runs.
  • Speak elements 46 along the direction of injection 48.
  • This arrangement of the magnetic sensors 46 is particularly well suited for determining a lateral displacement of the position of the respective permanent magnet 40a, 40b, 42a and 42b along the direction of injection 48 with a reduction in the
  • a two- or three-dimensional array of magnetic sensors 46 may also be formed. If the adhesive label 10 is attached to the container 12 and the
  • the at least one magnetic sensor 46 is each designed such that in each case a field strength information with respect to a present at the respective magnetic sensor 46 magnetic field strength of a magnetic field of at least one permanent magnet 40a, 40b, 42a and 42b of the magnetic sensor 46 can be output or tapped off on the magnetic sensor 46.
  • the at least one magnetic sensor 46 may be e.g. a (on a flexible substrate) printed measuring elements and / or a chip sensor (an integrated component, IC) be.
  • As the at least one magnetic sensor 46 at least one Hall element, at least one giant magnetoresistance element, at least one anisotropic magnetoresistive element, at least one flip-core element, and / or at least one tunnel magneto
  • Resistance element can be used.
  • Such sensor elements are relatively inexpensive and require relatively little volume / area.
  • the at least one sensor signal of the fill level detection device 44 is / is then determined taking into account the at least one field strength
  • the at least one sensor signal of the fill level detection device 44, or the at least one information signal derived therefrom, for evaluating the respective position and / or position of the respective permanent magnet 40a, 40b, 42a and 42b evaluated become. Based on the respective position and / or position of the respective permanent magnet 40a, 40b, 42a and 42b then the level of the liquid, powdery and / or gelatinous material in the container 12 (or the material cartridge 16) can be reliably determined. This one
  • Level detection means 44 described thus provides a magnetic
  • the level can be reliably determined, although the level detection device 44 is activated / energized only during the energization of the sensor device 28 by means of the supply current signal.
  • the magnetic sensor system described here thus also realizes an energy-saving possibility for determining the filling level, which harmonises well with the omission of the equipment of the sensor device 28 with an energy store.
  • the at least one permanent magnet 40a, 40b, 42a and 42b thus each fulfill a function of a "magnetic cartridge indicator.”
  • the container 12 already has a linearly adjustable sealing element (such as a punch) which is designed such that, provided the liquid, powdered and / or gelatinous material is filled in the container 12, the material can be pressed out of the container 12 at least partially by means of the linearly displaced sealing element
  • a mechanical emptying device of the container 12 already known from the prior art can easily cooperate are used with the at least one permanent magnet 40a, 40b, 42a and 42b as a "magnetic cartridge indicator”. It is sufficient if the permanent magnet 40a, 40b, 42a and 42b or at least one of the permanent magnets 40a, 40b, 42a and 42b of the container 12 attached to the sealing member or as at least part of
  • FIGS. 2c to 2f each show an end-of-content ring element 40a
  • the emptying ring elements shown in Figs. 2c to 2f can each on a (not shown) threaded rod of the container 12 may be arranged so that they in an initiation of an injection by rotation of the threaded rod in the (parallel to the threaded rod aligned)
  • Injection 48 are linearly shifted. With each injection, the emptying ring member 40a, 40b, 50a and 50b shifts (corresponding to the set injection amount), the linear displacement of the
  • Discharge ring member 40a, 40b, 50a and 50b only occurs when really a reduction in the level of the filled in the container 12 material occurs.
  • the emptying ring member 40a, 40b, 50a and 50b can be easily secured against "slipping back" against the direction of injection 48, for example by snap hooks on its outer contour or a slip-back protection.
  • the evacuation ring member 40a or 40b itself is magnetized.
  • the permanent magnet 42a or 42b is fixed to the drain ring member 50a or 50b.
  • a main magnetization direction 54 of the permanent magnet 40a, 40b, 42a or 42b is parallel to the injection direction 48.
  • Partial annular emptying ring member 40b or 50b are used.
  • 3a to 3c show schematic total and partial views of a third embodiment of the adhesive label, or the container equipped therewith.
  • the adhesive label 10 is shown separated from the container 12 for the sake of clarity.
  • the adhesive label 10 and the container 12 equipped therewith may have the features of the embodiments described above.
  • the container 12 comprises a mechanism / injection mechanism of a linearly adjustable (not shown) sealing element and a threaded rod 56 which are formed such that the sealing member by means of a rotation 58 of the threaded rod 56 (about the injection direction 48 / a
  • the container 12 has at least one permanent magnet 60, wherein the permanent magnet 60 (or at least one of the
  • Permanent magnet of the container 12 attached to the threaded rod 56 or formed as at least part of the threaded rod 56.
  • the threaded rod 56 may in particular either be magnetized itself or with the
  • Permanent magnet 60 be equipped so that by the rotation 58 of the threaded rod 56 has a main magnetization direction 54 of the respective permanent magnet 60 about the injection direction 48 / longitudinal direction of the
  • Threaded rod 56 rotates (see Fig. 3c).
  • the threaded rod 56 itself can be used as a "magnetic cartridge indicator”.
  • FIG. 3 b shows a three-dimensional array of magnetic sensors 46, which are arranged on and / or in the adhesive label 10 in such a way that they engage
  • the detection techniques of the two previously described embodiments can also be combined with each other. In both detection techniques it is ensured that all moving permanent magnets 40a, 40b, 42a, 42b and 60 are always in close proximity to one or more magnetic sensors 46. It is again pointed out that all the previously described embodiments do not require their own energy storage and storage for data.
  • the figures described above also disclose a method for operating a sensor device 38 for a container 12 with the steps: affixing an adhesive label 10 to the sensor device 28 arranged on and / or in the adhesive label and to an antenna device 26 arranged on and / or in the adhesive label 10 on the container 12, sending an electromagnetic Signal 32 from an external device 30 to the antenna device 26, whereby by means of the antenna device 26, a supply current signal of the sensor device 28 is generated and outputs the energized by means of the supply current signal sensor device 28 at least one sensor signal; and transmitting the at least one sensor signal output by the energized sensor device and / or at least one information signal derived from the at least one sensor signal by means of the
  • Antenna device 26 to the external device 30. It can, at least sometimes when the sensor device 28 is energized by means of the supply current signal, by means of at least one magnetic sensor 46 of the
  • Sensor device 28 a respective position and / or position of at least one permanent magnet 40a, 40b, 42a, 42b and 60, which is arranged in the container 12 so that the respective position and / or position of the respective permanent magnet 40a, 40b, 42a, 42b and 60 is varied in a reduction of a level of a filled into the container 12 liquid, powdery and / or gel material, are determined by means of the at least one magnetic sensor 46 each field strength information with respect to a present at the respective magnetic sensor 46 magnetic field strength a magnetic field of the at least one
  • Permanent magnets 40a, 40b, 42a, 42b and 60 is determined.
  • the at least one sensor signal can then be output taking into account the at least one field strength information.
  • the method may also include other of the features and / or operations described above.
  • Figs. 4a to 4f are schematic diagrams for explaining a
  • pressing the button 22 for injection causes a characteristic
  • Noise such as a click.
  • the characteristic noise arises, for example, in that when pressing the button 22 at least one mechanical spring 102 against at least one
  • the container 100 has at least one acceleration sensor 106, which is arranged on and / or in the container 100, that the
  • the characteristic noise / the structure-borne sound signal by means of the at least one acceleration sensor 106 is detectable.
  • the at least one acceleration sensor 106 can thus a
  • a number of the resonator 104 is an integer multiple of a number of an adjustable per full revolution of the selection mechanism injection quantity. If, for example, an amount of ten units of the liquid, pulverulent and / or gel material per full revolution is adjustable, then ten, twenty or thirty resonator bodies 104 can provide a corresponding number of characteristic structure-borne sound signals.
  • a number of the mechanical springs 102 may be proportional to the number of injection quantities that can be set per full revolution.
  • FIGS. 4c and 4d show a 1-dimensional structure-borne sound signal S and a 3-dimensional structure-borne sound signal S x , S y and S z , as can be detected by means of the at least one acceleration sensor 106. It can be seen that striking the at least one mechanical spring 102 on the at least one resonant body 104 causes a characteristic waveform of the structure-borne sound signal, which can be used as a "fingerprint" for verification. Acceleration signals, such as, for example, trembling of a patient or an environmental influence, thus do not contribute to the falsification of a level determined by the at least one acceleration sensor 106 of the liquid, pulverulent and / or gel-like material in the container 100. For the evaluation / verification of the structure-borne noise signal simple algorithms, such as wavelet transforms or Envelope comparisons, and / or complex algorithms, such as Fourier transforms or FFT, are used.
  • the at least one acceleration sensor 106 may be placed comparatively close to the at least one mechanical spring 102 and / or to the at least one resonator 104 Coupling between the at least one acceleration sensor 106 and the at least one structure-borne sound generation pair 102 and 104 ensure good detection of the generated structure-borne sound signal.
  • FIGS. 4 e and 4 f represent two alternative examples of a fill level measuring system formed with the at least one acceleration sensor 106.
  • a switch 108 may activate / wake up the at least one acceleration sensor 106 at the start of each injection.
  • the switch 108 may be a mechanical switch 108 which is automatically actuated by pressure of the button 22.
  • the at least one activated acceleration sensor 106 then counts the material withdrawals associated with the detected structure-borne sound signals. Each detected material removal thus increases a count and allows a reliable determination of the current level of the container 100.
  • the count can then be stored on a permanent memory 110.
  • the permanent memory 110 may be, for example, a ROM, an EEPROM, an EPROM, a RAM, an SRAM, a DRAM, a flash, or a magnetic storage medium. However, the storage media listed here are only to be interpreted as examples.
  • a transmitter 112 data can be stored in the permanent memory 110 and read from the permanent memory 110 and transmitted via an interface 114.
  • the transmitter 112 may, for example, a
  • the interface 114 may be a wired interface such as USB or single-wire, or a wireless interface such as Bluetooth.
  • the transmitter 112 can also be used to read a time counter 116, by means of which a time of injection is determined.
  • the time counter 116 may, for example, a
  • This data may additionally be transferable via the interface 114. (From these data can be, for example
  • the time counter 116 may also be integrated into the transmitter 112.
  • the time counter 116 may be RC oscillators or integrated chips (such as real-time clocks, RTC).
  • each of the systems schematically illustrated in FIGS. 4e and 4f may be formed on a flexible substrate which transmits mechanical vibrations well.
  • the suitable flexible substrate may be for example a foil, a flex PCB, or a (normal) printed circuit board (PCB).
  • an energy storage such as a battery (in particular a button cell) can be used.
  • each system can also be equipped with a (not shown)
  • a temperature determined by means of the temperature sensor can be used to improve a measurement accuracy or to compensate for a temperature drift.
  • a temperature sensor at least one thermocouple, at least one temperature-dependent
  • Resistor and / or at least one semiconductor elements are used.
  • Figures 5a and 5b show partial schematic representations of a container which does not fall under the present invention.
  • Container / medicament container 100 may have all the features of the previous one have described embodiment.
  • the at least one mechanical spring 102 is attached to the knob 22, while the at least one resonator / resonator 104 is fixedly attached to the selector mechanism 20.
  • the at least one acceleration sensor 106 may be arranged directly on the at least one mechanical spring 102 and / or on the at least one resonance body 104.
  • Fig. 6 shows a schematic partial view of a container, which does not fall under the present invention.
  • Container / medicament container 100 differs from the previous embodiment only in that the at least one mechanical spring 102 on the selector mechanism 20 and the at least one
  • Resonator / resonator 104 are attached to the knob 22. Also in this
  • the at least one acceleration sensor 106 can be positioned directly on the at least one mechanical spring 102 or directly on the at least one resonance body 104, since maximum and unambiguous structure-borne noise signals are generated which can be reliably detected by means of the at least one acceleration sensor 106.
  • Fig. 7 shows a schematic partial representation of a container, which does not fall under the present invention.
  • partially reproduced by means of FIG. 7 partially
  • Container / Drug Container 100 recognizes the system, which may have all the features of the embodiment of Figs. 4a-4f, a start point and an end point of rotation 120 triggered by pressing the button 22 during injection of the liquid, powdered and / or gel material the container 100. By means of the starting point and the
  • End point can be a total rotation angle of the rotation 120 determine which correlates to the injection quantity. (This also applies to total rotation angle greater than 360 °.)
  • each resonator / resonator 104a-104d is formed so as to abut the at least one mechanical spring 102 thereto specific body sound signal S a to Sd triggers, which is unambiguously assignable as a unique fingerprint by means of the at least one acceleration sensor 106 the respective resonant body 104a to 104d.
  • each of the resonance bodies 104a to 104d has one
  • Figs. 8a to 8c are schematic diagrams for explaining one
  • FIGS. 8a to 8c partially schematically
  • Container / medicament container 100 may have all the features of the previous embodiments. However, the container 100 has a plurality of acceleration sensors 106a to 106c, which are arranged in such a way that a structure-borne noise signal S triggered by striking the mechanical spring 102 against a resonator / resonator 104 is supplied
  • a spacing can be set using the speed of sound to determine s c, in which the body sound generating pair is located by the respective acceleration sensor 106a to 106c from 102 and 104th An intersection P of
  • Structure-borne noise generation pairs 102 and 104 are also in this way, a starting point and an end point of a triggered by the pressing of the button 22 rotation 120 can be determined, resulting in the total rotation angle of the executed during the injection rotation 120. Further, on the basis of the total rotation angle, the correlating
  • Injection quantity can be determined.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne une étiquette adhésive (10) pour un récipient (12) qui est fixée ou qui peut être fixée sur le récipient (12), l'étiquette adhésive (10) comprenant un dispositif d'antenne (26) agencé sur et/ou dans l'étiquette adhésive (10) et un dispositif de détection (28) agencé sur et/ou dans l'étiquette adhésive (10), le dispositif d'antenne (26) étant conçu et fixé au dispositif de détection (28), de telle sorte qu'à la réception d'un signal électromagnétique (32) envoyé depuis un appareil externe (30) par le dispositif d'antenne (26), un signal de courant d'alimentation puisse être produit au moyen du dispositif d'antenne (26) et délivré au dispositif de détection (28). Le dispositif de détection (28) alimenté au moyen du signal de courant d'alimentation est conçu de manière à émettre au moins un signal de détection et l'au moins un signal de détection délivré par le dispositif de détection (28) alimenté et/ou au moins un signal d'information dérivé de l'au moins un signal de détection peuvent être envoyés à l'appareil externe (30) au moyen du dispositif d'antenne (26).
PCT/EP2018/077896 2017-10-18 2018-10-12 Étiquette adhésive pour un récipient WO2019076757A1 (fr)

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DE102017218551.1A DE102017218551A1 (de) 2017-10-18 2017-10-18 Haftetikett für einen Behälter
DE102017218551.1 2017-10-18

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002518108A (ja) * 1998-06-15 2002-06-25 メドラッド インコーポレイテッド シリンジ情報のコード化
WO2007107558A2 (fr) * 2006-03-20 2007-09-27 Novo Nordisk A/S Détermination du contenu d'une cartouche à l'aide de moyens capacitifs
US8574199B2 (en) 2006-07-03 2013-11-05 Novo Nordisk A/S Coupling for injection devices
AT513452A1 (de) * 2012-10-05 2014-04-15 Ait Austrian Inst Technology Abgabevorrichtung für Medikamente
US20140243750A1 (en) * 2011-10-07 2014-08-28 Novo Nordisk A/S System for Determining Position of Element
WO2015124081A1 (fr) * 2014-02-20 2015-08-27 江苏多维科技有限公司 Pompe seringue à injection précise et son procédé de fabrication
WO2015143058A1 (fr) * 2014-03-21 2015-09-24 Osprey Medical, Inc. Seringue pourvue d'un système optique pour surveiller la position de la tige de piston
WO2016166338A1 (fr) * 2015-04-16 2016-10-20 Sanofi-Aventis Deutschland Gmbh Capteur et ensemble de capteur pour la détermination capacitive d'un niveau de remplissage
WO2017021226A1 (fr) * 2015-07-31 2017-02-09 Sanofi-Aventis Deutschland Gmbh Capteur pour dispositif d'administration de médicament

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002518108A (ja) * 1998-06-15 2002-06-25 メドラッド インコーポレイテッド シリンジ情報のコード化
WO2007107558A2 (fr) * 2006-03-20 2007-09-27 Novo Nordisk A/S Détermination du contenu d'une cartouche à l'aide de moyens capacitifs
US8574199B2 (en) 2006-07-03 2013-11-05 Novo Nordisk A/S Coupling for injection devices
US20140243750A1 (en) * 2011-10-07 2014-08-28 Novo Nordisk A/S System for Determining Position of Element
AT513452A1 (de) * 2012-10-05 2014-04-15 Ait Austrian Inst Technology Abgabevorrichtung für Medikamente
WO2015124081A1 (fr) * 2014-02-20 2015-08-27 江苏多维科技有限公司 Pompe seringue à injection précise et son procédé de fabrication
WO2015143058A1 (fr) * 2014-03-21 2015-09-24 Osprey Medical, Inc. Seringue pourvue d'un système optique pour surveiller la position de la tige de piston
WO2016166338A1 (fr) * 2015-04-16 2016-10-20 Sanofi-Aventis Deutschland Gmbh Capteur et ensemble de capteur pour la détermination capacitive d'un niveau de remplissage
WO2017021226A1 (fr) * 2015-07-31 2017-02-09 Sanofi-Aventis Deutschland Gmbh Capteur pour dispositif d'administration de médicament

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