WO2019071385A1 - 发酵系统用监控装置 - Google Patents

发酵系统用监控装置 Download PDF

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Publication number
WO2019071385A1
WO2019071385A1 PCT/CN2017/105378 CN2017105378W WO2019071385A1 WO 2019071385 A1 WO2019071385 A1 WO 2019071385A1 CN 2017105378 W CN2017105378 W CN 2017105378W WO 2019071385 A1 WO2019071385 A1 WO 2019071385A1
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Prior art keywords
cleaning
flow channel
fermentation system
monitoring device
valve body
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PCT/CN2017/105378
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English (en)
French (fr)
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卓金星
王志猛
王锦燕
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卓金星
王志猛
王锦燕
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Priority to PCT/CN2017/105378 priority Critical patent/WO2019071385A1/zh
Publication of WO2019071385A1 publication Critical patent/WO2019071385A1/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices

Definitions

  • the invention relates to a monitoring device for a fermentation system.
  • a fermented product such as a bacterial culture tank or a food sterilization tank
  • a small portion is taken for collecting the sample and placed in a microscopic device for detection, when the fermented material is sealed in a sealing device.
  • the industry will connect the first-class channel to the sealing device and install a micro-module in the flow channel to observe the bacteria in the fermentation without being polluted by the outside world. the amount.
  • the main object of the present invention is to provide a monitoring device for a fermentation system, which has a cleaning system, which can effectively clean the flow channel without disassembling the flow channel and the micro-module, and can prevent the inside and the outside of the flow channel. Contaminated by contact.
  • the present invention provides a monitoring device for a fermentation system, which is provided in a fermentation system, and the monitoring device for the fermentation system comprises a first-class circuit, a detection module and a cleaning system.
  • One of the fluids to be detected in the fermentation system is for circulation to the flow channel, and at least one first valve body is disposed between the flow channel and the fermentation system to selectively control the flow path to communicate with the fermentation system.
  • the detection module is disposed in the flow channel and includes a micro-module through which the fluid to be detected can be observed.
  • the cleaning system includes a cleaning device and at least one second valve body disposed on the flow path to selectively control the cleaning device to communicate with the flow channel.
  • FIG. 1 is a schematic structural view of a preferred embodiment of the present invention.
  • FIG. 2 is a partial perspective view of a preferred embodiment of the present invention.
  • FIG. 3 is a schematic diagram of monitoring according to a preferred embodiment of the present invention.
  • 4 to 5 are schematic views showing the operation of a preferred embodiment of the present invention.
  • Figure 6 is a schematic view of cleaning according to a preferred embodiment of the present invention.
  • the monitoring device of the present invention is provided in a fermentation system 9 .
  • the monitoring device for the fermentation system includes a first-class channel 1 and a detection module 2 . And a cleaning system 3.
  • a fluid to be detected in the fermentation system 9 is circulated to the flow channel 1, and at least a first valve body 11 is disposed between the flow channel 1 and the fermentation system 9 to selectively control the flow channel 1 to communicate with the flow channel 1 Fermentation system 9.
  • the two ends of the flow path 1 are connected to the fermentation system 9 and two first valve bodies 11 are disposed.
  • the detection module 2 is located between the two first valve bodies 11 .
  • the detection module 2 is disposed on the flow channel 1 and includes a micro-module 21 through which the fluid to be detected can be observed to effectively observe microorganisms in the fluid to be detected.
  • the detecting module 2 further includes a two-slide 22, and when the two slides 22 are close to each other, the micro-module 21 is passed through The fluid to be detected in the gap between the two slides 22 can be observed. Therefore, the present invention can accurately detect the fluid to be detected of the fermentation system 9 without opening the fermentation system 9 to the outside and extract a portion of the fluid to be detected, and can effectively prevent the fluid to be detected in the fermentation system 9. It is connected to the outside world and is polluted by the outside world.
  • the cleaning system 3 includes a cleaning device 31 and at least one second valve body 32 disposed on the flow channel 1 to selectively control the cleaning device 31 to communicate with the flow channel 1. Further, the cleaning device 31 includes a cleaning source 311 and at least one delivery tube 312 that communicates with the flow channel 1 and the cleaning source 311. The cleaning fluid of the cleaning source 311 is connected to the flow channel via the delivery tube 312. 1, Each of the conveying pipes 312 is provided with a second valve body 32.
  • the cleaning device 31 includes two conveying pipes 312, and the two conveying pipes 312 are respectively provided with a second valve body 32.
  • the cleaning fluid of the cleaning source 311 is one of the conveying pipes.
  • 312 is delivered into the flow channel 1 and exits the flow channel 1 via another such delivery tube 312.
  • FIG. 6 when cleaning is to be performed, the two first valve bodies 11 are first closed, and then the two second valve bodies 32 are opened, and the cleaning fluid can flow into the flow channel 1 for cleaning.
  • the cleaning device 31 can effectively clean the flow channel 1 and avoid the micro-module 21 and The surface of the two slides 22 is fouled to effectively observe the fluid to be detected, and the inside of the flow path 1 during the cleaning process is prevented from being contaminated by contact with the outside.
  • the cleaning fluid may be at least one of sterile water, acidic water, alkaline water, dry air, etc., to use different cleaning fluids according to different acidity and alkalinity and viscosity of the fluid to be tested.
  • One of the flow channel 1 and the at least one delivery tube 312 is further provided with a third valve body 41, which is selectively connectable to the outside, so that the third valve body 41 can be used after use.
  • the cleaning fluid is directly discharged to the outside to prevent the cleaning fluid from flowing back to the cleaning source 311 to contaminate the cleaning source 311.
  • the flow channel 1 or the delivery pipe 312 is additionally provided with a pump 42 for forcibly driving the cleaning fluid to flow, thereby improving the cleaning efficiency.
  • the pump 42 is used. It is disposed in the flow channel 1 and additionally drives the flow of the fluid to be detected.
  • the present invention further includes at least an actuating member 43 disposed at least on the slide 22 to actuate the two slides 22 to move toward each other, which is an actuating member in this embodiment.
  • the detection module 2 further includes at least one telescopic mechanism 23, each of which is connected to a slide 22 and the flow path 1.
  • the two slides 22 are disposed on opposite sides of the flow path 1, at least One of the slides 22 is permeable to light, and the micro-module 21 is disposed on the side of the slide 22 that is permeable to light away from the other of the slides 22.
  • the telescopic mechanism 23 is a bellows body, and the bellows body is connected to the slide 22 and the flow channel 1, so that the slide 22 can be smoothly moved and can be effectively closed.
  • the flow path 1 prevents the fluid to be detected from flowing out to the outside.
  • the monitoring device for the fermentation system of the present invention does not need to disassemble the flow channel and the micro-module, and the cleaning device can effectively clean the flow channel, thereby avoiding the micro-module and the two-slide
  • the surface is fouled and the fluid to be detected cannot be effectively observed, and the inside of the flow path is prevented from being contaminated by contact with the outside during the cleaning process.

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  • Life Sciences & Earth Sciences (AREA)
  • Hydrology & Water Resources (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

一种发酵系统（9）用监控装置，其供设于一发酵系统（9），该发酵系统（9）用监控装置包括一流道（1）、一检测模组（2）及一清洗系统（3）；该发酵系统（9）内之一待检测流体供流通于该流道（1）；该检测模组（2）设于该流道（1）并包括一显微模组（21）；该清洗系统（3）包括一清洗装置（31），以选择性地控制该清洗装置（31）连通于该流道（1）。

Description

发酵系统用监控装置 技术领域
本发明有关于一种发酵系统用监控装置。
背景技术
一般于检测一发酵物(如细菌培养槽或是食物杀菌槽)之含菌量时，是取一小部分为采集样本并放置于一显微装置进行检测，当发酵物为密封于一密封装置时，为了避免打开密封装置时发酵物受到外界污染，业界便会在密封装置外接一流道，并在流道中装设显微模组，以在不受到外界污染的情形下观察发酵物之含菌量。
然而，当该显微模组及流道使用一段时间后，难免会发生发酵物堆积之问题，而导致显微模组之显微镜头或是载玻片之表面堆积脏污，而滋生细菌，如此会导致检测含菌量之准度下降，更严重地会导致镜头模糊而失去观察画面，而将流道及显微模组拆卸进行清洗之过程又极为繁琐，且容易导致流道及显微模组受到外界污染，存在亟待改善之缺弊。
因此，有必要提供一种新颖且具有进步性之发酵系统用监控装置，以解决上述之问题。
发明内容
本发明之主要目的在于提供一种发酵系统用之监控装置，具有一清洗系统，该清洗系统无须将流道及显微模组拆卸即可有效地清洗流道，另外可防止流道内部与外界接触而受到污染。
为达成上述目的，本发明提供一种发酵系统用监控装置，其供设于一发酵系统，该发酵系统用监控装置包括一流道、一检测模组及一清洗系统。该发酵系统内之一待检测流体是供流通于该流道，该流道与该发酵系统之间设有至少一第一阀体，以选择性地控制该流道连通该发酵系统。该检测模组设于该流道并包括一显微模组，通过该显微模组即可观察到该待检测流体。该清洗系统包括一清洗装置及至少一设于该流道之第二阀体，以选择性地控制该清洗装置连通于该流道。
附图说明
图1为本发明一较佳实施例之结构示意图。
图2为本发明一较佳实施例之局部立体图。
图3为本发明一较佳实施例之监控示意图。
图4至5为本发明一较佳实施例之操作示意图。
图6为本发明一较佳实施例之清洗示意图。
图中标号说明：
1：流道
2：检测模组
3：清洗系统
9：发酵系统
11：第一阀体
21：显微模组
22：玻片
23：伸缩机构 31：清洗装置
32：第二阀体
311：清洗源
312：输送管
41：第三阀体
42：泵
43：致动件
具体实施方式
以下仅以实施例说明本发明可能之实施态样，然并非用以限制本发明所欲保护之范畴，合先叙明。
请参考图1至6，其显示本发明之一较佳实施例，本发明之发酵系统用监控装置供设于一发酵系统9，该发酵系统用监控装置包括一流道1、一检测模组2及一清洗系统3。
该发酵系统9内之一待检测流体供流通于该流道1，该流道1与该发酵系统9之间设有至少一第一阀体11，以选择性地控制该流道1连通该发酵系统9。于本实施例中该流道1之两端连接于该发酵系统9并设有二该第一阀体11，该检测模组2位于该二第一阀体11之间。
该检测模组2设于该流道1并包括一显微模组21，通过该显微模组21即可观察到该待检测流体，以有效观察到该待检测流体内之微生物。详细的说，如图4至5所示)，于本实施例中该检测模组2另包括二玻片22，当该二玻片22相互靠近贴合时，通过该显微模组21即可观察到该二玻片22之缝隙内的该待检测流体。因此，无需进行将该发酵系统9打开连通外界及取出部分该待检测流体，本发明即可准确地检测出该发酵系统9之待检测流体，并且可有效防止该发酵系统9内之待检测流体连通外界而遭到外界之污染。
该清洗系统3包括一清洗装置31及至少一设于该流道1之第二阀体32，以选择性地控制该清洗装置31连通于该流道1。进一步的说，该清洗装置31包括一清洗源311及至少一连通该流道1与该清洗源311之输送管312，该清洗源311之一清洗流体是经由该输送管312连通于该流道1， 各该输送管312设有一该第二阀体32。
具体而言，于本实施例中该清洗装置31包括二该输送管312，该二输送管312分别设有一该第二阀体32，该清洗源311之该清洗流体是自其中一该输送管312输送至该流道1内，并经由另一该输送管312排出该流道1。如图6所示，当欲进行清洗时，先将该二第一阀体11进行关闭，再开启该二第二阀体32，该清洗流体即可流至该流道1内，以进行清洗流道1、该检测模组2之过程，因此无须将该流道1及该显微模组21拆卸，该清洗装置31即可有效地清洗该流道1，避免该显微模组21及该二玻片22之表面堆积污垢而无法有效观察到该待检测流体，另外可防止清洗过程中该流道1内部与外界接触而受到污染。
要说明的是，该清洗流体可为无菌水、酸性水、碱性水及干燥空气等至少其中之一，以根据不同之待检测流体的酸碱性、黏稠度而交叉使用不同之清洗流体。该流道1及该至少一输送管312其中一者另设有一第三阀体41，该第三阀体41是可选择性地连通至外界，因此该第三阀体41即可将使用过后之该清洗流体直接排至外界，以避免该清洗流体流回该清洗源311而污染该清洗源311。
较佳地，于本实施例中其中一该流道1或一该输送管312另设有一泵42，以强制性地带动该清洗流体流动，进而提高清洗效率，于本实施例中该泵42是设于该流道1，另外可带动该待检测流体流动。
另外，本发明另包括至少一致动件43，该至少一致动件43至少设于一该玻片22，以致动该二玻片22相互靠近移动，于本实施例中是为一该致动件43，该检测模组2另包括至少一伸缩机构23，各该伸缩机构23连接于一该玻片22与该流道1，该二玻片22设于该流道1之相对二侧，至少一该玻片22为可透光，该显微模组21设于可透光之该玻片22远离另一该玻片22之一侧。
值得一提的是，于本实施例中该伸缩机构23为蛇腹管体，该蛇腹管体连接于该玻片22与该流道1，如此可顺利地移动该玻片22，且可有效封闭该流道1以防止该待检测流体流出至外界。
综上，本发明之发酵系统用之监控装置，无须将该流道及该显微模组拆卸，该清洗装置即可有效地清洗该流道，避免该显微模组及该二玻片之表面堆积污垢而无法有效观察到该待检测流体，另外可防止清洗过程中该流道内部与外界接触而受到污染。

Claims (10)

  1. 一种发酵系统用监控装置，供设于一发酵系统，包括：
    一流道，该发酵系统内之一待检测流体供流通于该流道，该流道与该发酵系统之间设有至少一第一阀体，以选择性地控制该流道连通该发酵系统；
    一检测模组，设于该流道并包括一显微模组，通过该显微模组即可观察到该待检测流体；
    一清洗系统，包括一清洗装置及至少一设于该流道之第二阀体，以选择性地控制该清洗装置连通于该流道。
  2. 如权利要求1所述的发酵系统用监控装置，其中该检测模组另包括二玻片，当该二玻片相互靠近贴合时，通过该显微模组即可观察到该二玻片之缝隙内的该待检测流体。
  3. 如权利要求2所述的发酵系统用监控装置，其中另包括至少一致动件，该至少一致动件至少设于一该玻片，以致动该二玻片相互靠近移动，该检测模组另包括至少一伸缩机构，各该伸缩机构连接于一该玻片与该流道，该二玻片设于该流道之相对二侧，至少一该玻片为可透光，该显微模组设于可透光之该玻片远离另一该玻片之一侧。
  4. 如权利要求1所述的发酵系统用监控装置，其中该流道之两端连接于该发酵系统并设有二该第一阀体，该检测模组位于该二第一阀体之间。
  5. 如权利要求1所述的发酵系统用监控装置，其中该清洗装置包括一清洗源及至少一连通该流道与该清洗源之输送管，该清洗源之一清洗流体经由该输送管连通于该流道，各该输送管设有一该第二阀体。
  6. 如权利要求5所述的发酵系统用监控装置，其中该清洗装置包括二该输送管，该二输送管分别设有一该第二阀体，该清洗源之该清洗流体自其中一该输送管输送至该流道内，并经由另一该输送管排出该流道。
  7. 如权利要求5所述的发酵系统用监控装置，其中该清洗流体为无菌水、酸性水、碱性水及干燥空气等至少其中之一。
  8. 如权利要求5所述的发酵系统用监控装置，其中该流道及该至少一输送管其中一者另设有一第三阀体，该第三阀体可选择性地连通至外界。
  9. 如权利要求5所述的发酵系统用监控装置，其中一该流道或一该输送管另设有一泵，以强制性地带动该清洗流体流动。
  10. 如权利要求3所述的发酵系统用监控装置，其中该流道之两端连接于该发酵系统并设有二该第一阀体，该检测模组位于该二第一阀体之间；该清洗装置包括一清洗源及至少一连通该流道与该清洗源之输送管，该清洗源之一清洗流体经由该输送管连通于该流道，各该输送管设有一该第二阀体； 该清洗装置包括二该输送管，该二输送管分别设有一该第二阀体，该清洗源之该清洗流体自其中一该输送管输送至该流道内，并经由另一该输送管排出该流道；该清洗流体为无菌水、酸性水、碱性水及干燥空气等至少其中之一；该流道及该至少一输送管其中一者另设有一第三阀体，该第三阀体可选择性地连通至外界；其中一该流道或一该输送管另设有一帮浦，以强制性地带动该清洗流体流动。
PCT/CN2017/105378 2017-10-09 2017-10-09 发酵系统用监控装置 WO2019071385A1 (zh)

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US20220268679A1 (en) * 2021-02-24 2022-08-25 Precision Fermentation, Inc. Devices and methods for monitoring
US11655444B2 (en) 2017-09-28 2023-05-23 Precision Fermentation, Inc. Methods, devices, and computer program products for standardizing a fermentation process

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