WO2019017675A1 - Stent complexe et son procédé de fabrication - Google Patents

Stent complexe et son procédé de fabrication Download PDF

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Publication number
WO2019017675A1
WO2019017675A1 PCT/KR2018/008068 KR2018008068W WO2019017675A1 WO 2019017675 A1 WO2019017675 A1 WO 2019017675A1 KR 2018008068 W KR2018008068 W KR 2018008068W WO 2019017675 A1 WO2019017675 A1 WO 2019017675A1
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Prior art keywords
stent
window
composite
coating
rti
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PCT/KR2018/008068
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English (en)
Korean (ko)
Inventor
박도현
Original Assignee
울산대학교 산학협력단
재단법인 아산사회복지재단
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Publication of WO2019017675A1 publication Critical patent/WO2019017675A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/856—Single tubular stent with a side portal passage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/18—Materials at least partially X-ray or laser opaque
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/041—Bile ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/043—Bronchi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2002/065—Y-shaped blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/821—Ostial stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers

Definitions

  • the present invention relates to an implantable medical device and a method of manufacturing the same, and more particularly to a composite stent device that can be inserted into a region having a Y-shaped path, such as a bile duct or a bronchus, and a method of manufacturing the same.
  • the hepatobiliary duct is Y-shaped, and the tumor usually develops at the Y-splitting site. Therefore, biliary stenosis may be caused by tumor, and stent implantation is mainly used to solve this problem.
  • Korean Patent No. 10-1157918 (registered on June 13, 2012) proposes a biliary stent and a method for manufacturing the same. More specifically, this invention relates to a Y-shaped stent adapted to the shape of the bile duct.
  • a stent comprising: a first stent including at least one fenestration for allowing one or more other stents to pass through one side of the stent; And at least one second stent coupled through a window of the first stent.
  • a composite stent which further comprises a radiation non-transmissive marker disposed in the first stent and indicative of the position of the window. And a lasso connected to one side of the first stent or the second stent and used for removing the complex stent.
  • the composite stent may be a shape memory alloy including nitinol, which is a Ni-Ti alloy, and the first stent and the second stent, The inside may further include a coating.
  • a composite stent in which the inner coating of the second stent is present only outside the window of the first stent, and the inner coating of the second stent is composed of silicon or PTFE (Polytetrafluoroethylene) is also disclosed .
  • the first stent or the at least one second stent is changed to a shape corresponding to the inserted position of the subject in the human body when the composite stent is inserted by 4D printing.
  • a composite stent in which the window of the first stent is formed in the form of a bud protruding outward of the first stent.
  • the composite stent further comprises another window for passing a third stent through one side of the first stent, and further comprising a third stent passing through the other window of the first stent Complex stents are also disclosed.
  • the first stent includes a plurality of windows, and a plurality of Nth stents passing through the plurality of windows are possible.
  • a method comprising: forming a first stent including one or more fenestrations that allow one or more other stents to pass through one side of the stent; And forming a second stent coupled through the window of the first stent.
  • a method of manufacturing a composite stent may further include forming a radiopathology marker disposed on the first stent and indicating a position of the window, wherein the first stent is connected to one side of the first stent or the second stent Thereby forming a lasso used for the removal of the complex stent.
  • the composite stent may be formed of nitinol, and the method may further include forming a coating on the inside of the first stent and the second stent.
  • a method of manufacturing a composite stent wherein the inner coating of the second stent is formed only outside the window of the first stent, and the inner coating of the second stent is formed of a composite stent made of silicon or PTFE (Polytetrafluoroethylene) A manufacturing method is also possible.
  • a window of the first stent is formed in the form of a bud protruding outward of the first stent.
  • a method of manufacturing a stent comprising: forming another window for passing a third stent through a first stent; And forming a third stent through the other window of the first stent. Also, in some cases, a method of manufacturing a composite stent including a plurality of Nth stents passing through the plurality of windows is possible, wherein the first stent includes a plurality of windows.
  • Figure 1 shows a liver bile duct according to one embodiment.
  • Figure 2 illustrates a first stent of a composite stent according to one embodiment.
  • Figure 3 illustrates a composite stent according to one embodiment.
  • FIG. 4 illustrates a composite stent comprising a radiation marker according to one embodiment.
  • Figure 5 illustrates a composite stent comprising a lasso, according to one embodiment.
  • FIG. 6 illustrates a coated composite stent according to one embodiment.
  • FIG. 7 illustrates a lasso connected to a second stent according to one embodiment.
  • Figure 8 illustrates a first stent comprising a protruding window in accordance with one embodiment.
  • FIG. 9 illustrates an endoscopic retrograde cholangiopancreatography (ERCP) delivery system used in the insertion of a composite stent according to an embodiment.
  • ERCP endoscopic retrograde cholangiopancreatography
  • FIG. 10 shows an insertion instrument used for insertion of a composite stent according to one embodiment.
  • Figure 1 shows a liver bile duct according to one embodiment.
  • 1 shows a hepatic duct bile duct 130 in which a liver 100, a bile duct 120 and a bile duct are split into a Y-shape.
  • the bile produced in the liver 100 moves to the liver bile duct 130 along the intrahepatic bile duct and is stored in the gallbladder.
  • the stored bile is excreted through the bile duct 120 to the duodenum during digestion.
  • stenting is used when stenosis is caused by the tumor generated in the hepatic bile duct 130 and bile can not be discharged smoothly.
  • FIG. 2 illustrates a first stent 200 of a composite stent according to one embodiment.
  • the composite stent may be composed of a first stent 200 and a second stent.
  • the first stent 200 will be described in detail with reference to FIG. 2, and the second stent will be described with reference to FIG.
  • the first stent 200 may be a self-expanding stent, and a fenestration 210 may be present on one side of the first stent 200.
  • the window 210 may be in the form of a rhombus, but is not limited thereto.
  • the second stent is passed through the window 210 of the first stent 200. The state in which it passes is shown in FIG.
  • Figure 3 illustrates a composite stent according to one embodiment. As described above, a composite stent including a first stent 300 and a second stent 320 is shown. The second stent 320 is passed through the window 310 of the first stent 300.
  • the first stent 300 is first inserted into the bile duct, and the second stent 320 is inserted sequentially.
  • the window 310 of the first stent does not necessarily have to be in a specific shape but is in contact with the contour of the second stent 320 when the second stent 320 is self-
  • a Y-shape can be formed. That is, the second stent may be coupled to one side of the first stent to form a Y-shape.
  • the Y-shaped composite stent including the first stent and the second stent may further include any one of a radiation non-transmissive marker, a lasso, and a coating. It may also include all three.
  • the stent in a Y-shaped composite stent including a first stent and a second stent, the stent includes a radiopaque marker in the vicinity of the window of the first stent, and includes lasso at the distal end of the second stent, A composite stent including a coating inside the stent and the second stent is also possible.
  • the film of the first stent may have a window like the first stent, and the film of the second stent may exist only outside the window. In the case where the coating of the second stent is present only on the outer side of the window, the bile flow inside the first stent can be smoothly maintained.
  • the coating of the second stent may be composed of silicon or PTFE.
  • PTFE fine bubbles existing in the PTFE can prevent the biliary flow of the intra-hepatic biliary branch from being disturbed.
  • the details of the radiation non-penetrating marker, the lacquer, and the coating film will be described in detail with reference to FIGS. 4 to 6, respectively.
  • a component a radiopaque marker, a coating film, or the like
  • the form is also possible.
  • the first stent or the at least one second stent may be a composite stent that changes shape corresponding to the insertion position of the subject when the composite stent is inserted by 4D printing. That is, when 4D printing is used to insert the second stent after insertion of the first stent, the second stent is inserted in a form that is easy to insert, and after the insertion is completed, It can be smoothly connected.
  • the second stent is made of a shape memory alloy using 4D printing, inserted into the window of the first stent in a compressed form that is easy to insert, and unilateral shortening occurs after the insertion is completed,
  • the joining portions of the second stent can be smoothly connected.
  • the first stent 400 may include a window 410 formed on one side and a radiation marker 420 formed around the window.
  • a second stent includes a radiation marker 420 to be guided through the window 410 within the first stent 400. And a radiation non-transmissive marker 420 for easily grasping the position of the window 410 in the first stent 400 during a fluoroscopic procedure.
  • the radiation non-penetration marker 420 may be positioned at the upper end of the first stent (the entering direction of the endoscope) and the lower end (the advancing direction of the endoscope) about the window 410.
  • the radiation non-transmissive markers 420 are illustratively represented as a pair of two, but are not stable and may be one or more. That is, the number of the radiation markers 420 is not limited to the number, and one or more radiation markers 420 may be positioned at the periphery of the window 410.
  • the lasso is also called a pull cord and is used to remove the stent from the inside of the body. When pulling the lasso, it is easy to remove it as the stent is tightened.
  • the lasso can be configured to pivot about one end of the stent to pull the stent out.
  • Figure 5 illustrates a composite stent comprising a lasso, according to one embodiment.
  • the first stent 500 or the second stent may include a lasso 520.
  • 5 illustrates a case where the first stent 500 includes the lasso 520, but the present invention is not limited thereto and the lasso 520 may be connected to the second stent.
  • the case where Lasso is connected to the second stent will be described in detail in Fig.
  • the first stent 500 includes a window 510 on one side and a lasso 520 on the distal end.
  • the entire stent may be removed by pulling one lasso connected to the first stent or the second stent.
  • the lasso is connected to the second stent, it is easier to remove the entire composite stent at one time.
  • it is possible to remove the entire complex stent at once.
  • the composite stent may include a coating 610.
  • 6 illustrates a case where the first stent 600 has a coating 610 as an example.
  • the second stent may also include a coating.
  • the coating 610 may be present inside or outside the first stent 600.
  • Figure 6 shows the case where the coating 610 is inside.
  • the coating 610 includes a fenestration so that the second stent can pass therethrough like the first stent 600.
  • the coating 610 also prevents the tumor from infiltrating into the interior of the stent. Therefore, the material may be composed of silicon.
  • the coating 610 may be different if the coating 610 is present in the second stent. More specifically, when the coating is present in the second stent, a coating may be present only in a portion protruding outwardly coupled with the first stent, or a portion protruding outward from the first stent, A portion of the first stent may be formed of PTFE (Polytetrafluoroethylene).
  • PTFE Polytetrafluoroethylene
  • the portion of the first stent protruding to the outside is to contain the silicone coating to prevent invasion of the tumor and to allow the bile and the like to be permeated into the stent.
  • the silicone coating may block the discharge of the solution and may cause complications such as cholangitis.
  • the PTFE has fine pores and does not transmit large sized tumors, Bile and the like can be transmitted.
  • the composite stent may include a first stent 700, a second stent 710, and a lasso 720.
  • the lasso 720 may be connected to the second stent 710.
  • the lasso 720 may be connected to the distal end of the second stent 700 existing in the first stent 700.
  • the distal end of the second stent 700 is connected to the distal end of the second stent 700
  • the lasso 720 is pulled, the first stent is closed and the first and second stents are connected to each other. Due to the frictional force of the part, the entire composite stent can be removed at once.
  • Figure 8 illustrates a first stent comprising a protruding window in accordance with one embodiment.
  • the composite stent may include a first stent 800 including a protruding window 810,
  • the window 810 may be partially protruded in the form of a bud.
  • the window 810 protrudes in the form of a bud, it is possible to more easily engage the second stent when the second stent is coupled to the first stent.
  • the length of the protruding portion may be, for example, 5 mm, but not limited thereto.
  • the portion of the bile duct or the bronchus which is split in the Y-shape And may be selected to an appropriate length to facilitate insertion of the second stent.
  • FIG. 9 illustrates an endoscopic retrograde cholangiopancreatography (ERCP) delivery system used in the insertion of a composite stent according to an embodiment.
  • the delivery system may include a sheath hub 910, a cap 920, a connector 930, a pusher 940, and a pusher hub 950.
  • the sheath hub 910 includes a sheath surrounding the stent.
  • the pusher 940 serves to push the stent to a desired position and adjusts it using a pusher hub 950.
  • a composite stent In order to insert a composite stent, first insert an endoscope into the duodenum. An insertion mechanism is inserted through the endoscope apparatus, and a contrast is injected through the insertion mechanism. Then, guide wires (Guidewire) are inserted into both sides of the bifurcated portion of the bile duct along the insertion mechanism, and the insertion mechanism is removed. Next, the delivery system is inserted along the guidewire. The delivery system places the first stent and the second stent at desired positions and installs the composite stent. The delivery system inserts the first stent and the second stent along two guidewires inserted into both sides of the Y-shaped part of the bile duct. Once all of the complex stents are installed, the delivery system, guide wire, and endoscope are sequentially removed.
  • guide wires Guidewire
  • the method of inserting the stent is applicable not only to the bile duct but also to the bronchial tube.
  • an endoscope may be inserted into the Y-shaped portion of the bronchus, the guide wire may be inserted into the Y-shaped divided portions, and a first stent and a second stent may be provided along the guide wire.
  • the composite stent is inserted into the stent in a stent-in-stent manner, in which another stent is inserted into one stent.
  • the insertion tool may include an introducer 1010, and two guide wires 1030 and 1040 are inserted to insert the composite stent.
  • the insertion mechanism may include a side hole 1020 to insert the guide wire.
  • the stent introducer 1010 has a cylindrical structure having a side hole 1020 at the distal end and the guide wires 1030 and 1040 pass through the body of the introducer 1010 and the distal side hole 1020, respectively .
  • the guide wires 1030 and 1040 serve to orient the fenestration of the stent. Therefore, the introducer 1010 can position each guide wire in the Y-shape in the vicinity of the Y-shaped portion of the bile duct.
  • the delivery system can accurately position the stent to each Y-shaped portion of the bile duct along the guide wires 1030 and 1040.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un stent complexe associé à un stent des voies biliaires ou des bronches, le stent complexe comprenant: un premier stent comprenant une fenestration sur un côté du stent de telle sorte qu'un stent différent peut passer; et un second stent couplé à travers la fenestration du premier stent.
PCT/KR2018/008068 2017-07-17 2018-07-17 Stent complexe et son procédé de fabrication WO2019017675A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170090327A KR101937574B1 (ko) 2017-07-17 2017-07-17 복합 스텐트 및 그 제조방법
KR10-2017-0090327 2017-07-17

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WO2019017675A1 true WO2019017675A1 (fr) 2019-01-24

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WO (1) WO2019017675A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
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RU202236U1 (ru) * 2020-08-28 2021-02-08 Государственное бюджетное учреждение здравоохранения города Москвы «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения города Москвы» (ГБУЗ "НИИ СП ИМ. Н.В. СКЛИФОСОВСКОГО ДЗМ") Эндобронхиальный стент

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