WO2019016904A1 - Flow passage opening/closing mechanism, and peritoneum dialysis device provided with said flow passage opening/closing mechanism - Google Patents

Flow passage opening/closing mechanism, and peritoneum dialysis device provided with said flow passage opening/closing mechanism Download PDF

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Publication number
WO2019016904A1
WO2019016904A1 PCT/JP2017/026163 JP2017026163W WO2019016904A1 WO 2019016904 A1 WO2019016904 A1 WO 2019016904A1 JP 2017026163 W JP2017026163 W JP 2017026163W WO 2019016904 A1 WO2019016904 A1 WO 2019016904A1
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WO
WIPO (PCT)
Prior art keywords
tube
flow path
closing mechanism
guide member
dialysate
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Application number
PCT/JP2017/026163
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French (fr)
Japanese (ja)
Inventor
祐卓 森田
吉田 英雄
Original Assignee
株式会社ジェイ・エム・エス
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Publication date
Application filed by 株式会社ジェイ・エム・エス filed Critical 株式会社ジェイ・エム・エス
Priority to PCT/JP2017/026163 priority Critical patent/WO2019016904A1/en
Priority to CN201780093208.4A priority patent/CN110891626B/en
Publication of WO2019016904A1 publication Critical patent/WO2019016904A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/159Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit specially adapted for peritoneal dialysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation

Definitions

  • the present invention relates to a flow path opening / closing mechanism for opening / closing a flow path of a liquid formed inside a flexible tube, and a peritoneal dialysis device provided with the flow path opening / closing mechanism.
  • a peritoneal dialysis apparatus After a predetermined amount of dialysate is aspirated from a dialysate bag containing dialysate, a step of feeding the aspirated dialysate into the abdominal cavity, and a predetermined amount of the peritoneal cavity After suctioning the dialysate (drainage), the drainage step of draining the suctioned dialysate (drainage) to the drainage bag is repeated respectively.
  • the peritoneal dialysis device has a plurality of flexible tubes each having one end connected to the dialysate bag or the drain bag, and a plurality of tubes other than the plurality of tubes.
  • a liquid feeding / draining cassette comprising a chamber connected to the end side and a diaphragm (diaphragm) partitioning the inside of the chamber, and a plurality of tubes of this liquid feeding / draining cassette are pressed to A flow path opening / closing mechanism that opens the flow path by closing and releasing the pressure, and an air pump that reciprocates the diaphragm by drawing air into and out of the chamber to suck or deliver a fixed amount of dialysate.
  • the flexible tube is deformed in a predetermined direction so as to crush the tube and the flow path is closed. Therefore, for example, when the temperature of the use environment of the peritoneal dialysis device is low, it takes time to restore the shape of the deformed tube when the flow passage is opened from the closed state of the flow passage, In some cases, the dialysis device erroneously detects that the flow path is blocked. In addition, there is also a problem that the time taken for liquid transfer / drainage of the dialysate is prolonged due to the delay in the restoration of the shape of the tube when the flow path is opened.
  • an object of the present invention is to provide a flow path opening / closing mechanism that is less likely to cause blockage of the flow path due to deformation of the tube, and a peritoneal dialysis device provided with the flow path opening / closing mechanism.
  • the present invention is a flow path opening / closing mechanism that opens and closes a flow path of a liquid formed inside a flexible tube, and a pressing member capable of pressing the tube, and advancing and retracting the pressing member in a first direction
  • the guide member is formed to have a width equal to or less than the outer diameter of the tube and extends in the first direction in the guide member body and the guide member body.
  • the present invention relates to a flow path opening / closing mechanism provided with a groove portion that holds in a second direction that intersects the direction.
  • the width of the groove is smaller than the outer diameter of the tube.
  • the said guide member is arrange
  • the flow path opening / closing mechanism includes a plurality of clamps disposed corresponding to a plurality of tubes, and the guide member has a plurality of grooves disposed corresponding to a plurality of clamps. Is preferred.
  • the flow channel opening / closing mechanism described above a plurality of the tubes each having one end connected to the dialysate supply source or the dialysate delivery destination, a chamber connected to the other end of the tube, and
  • the present invention relates to a peritoneal dialysis device including a liquid feeding / draining cassette provided with a diaphragm that divides the inside, and an air pump that reciprocates the diaphragm by drawing air in and out of the chamber to aspirate or deliver a fixed amount of dialysate.
  • the present invention it is possible to provide a flow path opening / closing mechanism that is less likely to cause blockage of the flow path due to deformation of the tube, and a peritoneal dialysis device provided with the flow path opening / closing mechanism.
  • FIG. 1 It is a perspective view showing a peritoneal dialysis device provided with a channel opening and closing mechanism concerning one embodiment of the present invention. It is a figure which shows the structure of the liquid feeding * drainage cassette of the peritoneal dialysis apparatus of this embodiment. It is an enlarged view of the flow-path opening-and-closing mechanism part in the peritoneal dialysis apparatus shown in FIG. It is a perspective view which shows the state in which the liquid feeding / drainage cassette was attached to the flow-path opening-and-closing mechanism. It is a top view which shows the state in which the liquid feeding * drainage cassette was attached to the flow-path opening / closing mechanism.
  • FIG. 7 is a view schematically showing an operation of a clamp unit, which corresponds to a cross section along line XX in FIG. 6;
  • FIG. 7 (a) shows a state in which the flow path of the tube is closed, and
  • FIG. 7 (b) shows a state in which the flow path of the tube is opened.
  • FIG. 7 is a view schematically showing an operation of a clamp unit, and a view corresponding to a cross section along line YY in FIG. 6;
  • FIG. 8 (a) shows a state in which the flow path of the tube is closed, and
  • FIG. 8 (b) shows a state in which the flow path of the tube is opened.
  • the flow path opening / closing mechanism 1 of the present embodiment is applied to a peritoneal dialysis device 100, as shown in FIG. First, the configuration of the peritoneal dialysis device 100 will be described.
  • the peritoneal dialysis apparatus 100 includes a dialysis apparatus main body 110, a heating unit 120 for storing and heating a dialysate bag, and a heating unit cover that covers the heating unit 120.
  • a liquid feeding / draining cassette 130 (see FIG. 2) for sucking and feeding a fixed amount of dialysate, a flow path opening / closing mechanism 1 for opening / closing a flow path of liquid feeding / draining cassette 130, liquid feeding
  • the air pump 140 for operating the drainage cassette 130, the cassette lid 112 covering the flow path opening / closing mechanism 1, and the operation unit 150 are provided.
  • the dialysis device body 110 constitutes the outer shape of the peritoneal dialysis device 100.
  • the heating unit 120 is disposed on the upper surface of the dialysis device body 110.
  • the heating unit 120 includes a storage unit 121 for storing the dialysate bag in which the dialysate is stored, and a heating mechanism (not shown) for heating the dialysate bag for heating.
  • the heating unit 120 heats the heating dialysate bag (dialysate) stored in the storage unit 121 to a predetermined temperature by the heating mechanism.
  • the temperature of the dialysate heated in the heating unit 120 is measured by the temperature sensor 123.
  • the heating unit lid 111 is attached to the dialysis device main body 110 so as to be openable and closable, and covers the heating unit 120.
  • the liquid feeding / draining cassette 130 includes a plurality of tubes 131, 132, 133, 134, 135, a chamber 136, and a plurality of diaphragms 137 disposed inside the chamber 136. And a fixing member 138 for fixing the tubes 131, 132, 133, 134, and 135 of the above.
  • the plurality of tubes 131, 132, 133, 134, and 135 are made of a flexible synthetic resin (for example, soft polyvinyl chloride).
  • each of the tubes 131, 132, 133, 134, and 135 is supplied with a dialysate supply source (a dialysate bag 101 for heating, a dialysate bag 102 for replenishment, a dialysate bag 103 for concentration change) or dialysis It is connected to a fluid delivery destination (intraperitoneal cavity of patient P, drainage bag 104).
  • a dialysate supply source a dialysate bag 101 for heating, a dialysate bag 102 for replenishment, a dialysate bag 103 for concentration change
  • a fluid delivery destination Intraperitoneal cavity of patient P, drainage bag 104.
  • the tube 131 is connected to the heating dialysate bag 101 stored in the heating unit 120, and constitutes a part or all of the heating line L1 (the same applies to the following).
  • the tube 132 is connected to the replacement dialysate bag 102 (in this embodiment, three replacement dialysate bags 102), and constitutes a replacement line L2.
  • the tube 133 is connected to the concentration change dialysate bag 103 containing dialysate having a concentration different from that of the dialysate contained in the replacement dialysate bag 102, and constitutes a concentration change line L3.
  • the tube 134 is connected to the peritoneal cavity of the patient P and constitutes a peritoneal line L4.
  • the tube 135 is connected to a drainage bag 104 for containing drainage, and constitutes a drainage line L5.
  • Each tube is connected to a bag or the like directly or via a connector.
  • the chamber 136 is made of a hard synthetic resin (for example, hard polyvinyl chloride) and is formed to a predetermined volume (for example, 100 ml).
  • the chamber 136 is formed in a shape in which parts of two identical spherical surfaces are bonded. At the centers of the two spherical surfaces of the chamber 136, through holes 136a for communicating the inside and the outside of the chamber 136 are formed, respectively.
  • the other end side of the plurality of tubes 131, 132, 133, 134, 135 is connected to one spherical through hole 136a.
  • the other ends of the plurality of tubes 131, 132, 133, 134, 135 are assembled into a single tube 139, and the assembled single tube 139 is one of the chambers 136. It is connected to a through hole 136a formed in a spherical surface.
  • the diaphragm 137 is formed of an elastic membrane member and defines the inside of the chamber 136.
  • the fixing member 138 includes a rectangular frame 138a, and a rod 138b having one end connected to the frame 138a and extending like a rod.
  • a plurality of fixing grooves 138c for fixing the tubes 131, 132, 133, 134, 135 in a state where the plurality of tubes 131, 132, 133, 134, 135 are arranged in parallel to each other in the frame portion 138a 2) are formed, and by fixing the tubes 131, 132, 133, 134, and 135 in these fixing grooves, the tubes 131, 132, 133, 134, and 135 are fixed to the frame portion 138a.
  • the rod portion 138 b is connected to the chamber 136 at the other end, and supports one tube 139 collected at the other end of the tubes 131, 132, 133, 134, 135.
  • the flow path opening / closing mechanism 1 is disposed on the upper surface of the dialysis device main body 110 as shown in FIGS. 1 and 3. As shown in FIGS. 3 to 5, the above-mentioned liquid feeding / draining cassette 130 is attached to the flow path opening / closing mechanism 1.
  • the flow path opening / closing mechanism 1 opens / closes the flow path of the plurality of tubes 131, 132, 133, 134, 135 of the liquid feeding / draining cassette 130.
  • the flow path opening / closing mechanism 1 includes a clamp unit 20 and a guide member 30.
  • the clamp part 20 is arrange
  • five sets of clamp portions 20 are arranged corresponding to the five tubes 131, 132, 133, 134, and 135, respectively. More specifically, as shown in FIGS. 3 to 6, in the present embodiment, the clamp portions 20 are arranged in two rows, and in one row (the right row in FIG. 5), the tubes 131 and 135 are provided. The clamp part 20 which opens and closes is arrange
  • the pressing member 21 is formed in a pointed (thin) shape with a tip (upper end) having a width slightly larger than the width (outside diameter) of the tube.
  • the pressing member 21 is disposed below the tube so that the width direction of the tip extends along the width direction of the tube.
  • the drive mechanism 22 includes a cam 221, a shaft member 222 connected to the cam 221 and serving as a rotation shaft, and a motor 223 for rotating the shaft member 222.
  • the drive mechanism 22 is configured to include two shaft members 222 and a motor 223 corresponding to the clamp portions 20 arranged in two rows.
  • the cam 221 for moving the pressing member 21 corresponding to the tubes 131 and 135 in the vertical direction (first direction) is attached to the shaft member 222 of one row (the right row in FIG. 6), and the other row
  • the cam 221 for moving the pressing member 21 corresponding to the tubes 132, 133 and 134 in the vertical direction is attached to the shaft member 222 of the left row in FIG.
  • the plurality of cams 221 attached to one shaft member 222 are arranged such that the positions of the major diameter portions are mutually offset.
  • the cam 221 is rotated by driving the motor 223 to rotate the shaft member 222. Then, as shown in FIGS. 7A and 8A, the pressing member 21 is moved upward by the pressing member 21 being pushed up by the long diameter portion of the cam 221, and FIGS. 7B and 7C. As shown in FIG. 8 (b), the pressing member 21 is moved downward by releasing the force with which the pressing member 21 is pushed up by the short diameter portion of the cam 221.
  • the pressing member 23 is disposed above the tube so as to face the pressing member 21 as shown in FIGS. 7 and 8. In the present embodiment, as shown in FIG. 1, the pressing member 23 is attached to the inner surface of the cassette lid 112 described later.
  • the guide member 30 is disposed in the vicinity of the clamp unit 20 as shown in FIGS. 4 and 5 and regulates the position of the tube. More specifically, the guide member 30 is a clamp portion 20 (pressing member 21 in each of the plurality of tubes 131, 132, 133, 134, 135 of the liquid feeding / draining cassette 130 attached to the flow path opening / closing mechanism 1). Placed on both sides of In the present embodiment, since the clamp portions 20 are arranged in two rows, the guide members 30 are arranged in four rows.
  • the guide member 30 includes a rectangular plate-like guide member main body 31 and a groove 32 formed in the guide member main body 31, as shown in FIGS.
  • the guide member main body 31 is disposed so that the longitudinal direction intersects (orthogonal to) the extending direction of the tube.
  • the guide member 30 is arrange
  • the groove portion 32 is formed to extend in the vertical direction (first direction) from a side edge located on the upper side in the guide member main body 31. Further, as shown in FIG. 9, the width D1 of the groove portion 32 is formed to have a portion having a width equal to or less than the outer diameter D2 of the tube in a non-tensioned state (natural state).
  • the tube is held in the horizontal direction (second direction) intersecting (orthogonal) in the vertical direction (first direction) by the groove 32 by being pushed into the groove 32, and the position is regulated.
  • the width D1 of the groove 32 is, for example, the width of the central portion of the groove 32 in which the tube is held when the width of the groove 32 is different (expands in diameter) from the lower side to the upper side.
  • the width D1 of the groove 32 is formed to be smaller than the outer diameter D2 of the tube.
  • the width D1 of the portion of the groove 32 that sandwiches the tube is preferably 3.5 mm to 5 mm, and more preferably 4 mm to 4.5 mm .
  • five grooves 32 are formed in one guide member 30 corresponding to the five tubes 131, 132, 133, 134 and 135. That is, the position of one tube is restricted by the four guide members 30 (grooves 32).
  • the two guide members 30 (grooves 32) among them hold the tube in the vicinity of the clamp 20 (pressing member 21).
  • the position where the guide member 30 is disposed is influenced by the diameter of the tube, but in the case of the above example (the tube outer diameter D2 is 5 mm), the range from 3.0 mm to 11.0 mm from the clamp portion 20 Preferably, the range is 5.0 mm to 9.0 mm.
  • the flow path opening / closing mechanism 1 described above operates as follows. First, the liquid feeding / draining cassette 130 is disposed in the flow path opening / closing mechanism 1.
  • the five tubes 131, 132, 133, 134, and 135 respectively have the groove portions 32 of the guide member 30 in the vicinity of the clamp portion 20 (both sides of the clamp portion 20). Position is restricted. Further, as shown in FIG. 9, the width D1 of the portion of the groove 32 for holding the tube is smaller than the outer diameter D2 of the tube.
  • a force (tension) is applied to the tube in the horizontal direction (second direction) on the closing side (arrow direction in FIG. 10).
  • the drive mechanism 22 is operated. That is, by driving the motor 223 to rotate the shaft member 222, the cam 221 is rotated. Then, as shown in FIGS. 7A and 8A, the pressing member 21 is moved upward by the pressing member 21 being pushed up by the long diameter portion of the cam 221, and the tube is moved up and down (first direction). Press to. Thereby, the flow path of the tube is closed (see FIG. 10). Further, as shown in FIGS. 7B and 8B, when the cam 221 is further rotated and the short diameter portion of the cam 221 comes to a position corresponding to the pressing member 21, a force by which the pressing member 21 is pushed up. Is released and the pressing member 21 moves downward. Thereby, the pressure of the tube is released and the flow path is opened.
  • the tube is pressed by the clamp unit 20 by arranging the guide member 30 in the vicinity of the clamp unit 20 and configuring the width D1 of the groove 32 to be equal to or less than the outer diameter D2 of the tube.
  • the tube in the groove 32, the tube can be restricted from spreading in the horizontal direction (second direction) intersecting with the vertical direction (first direction) pressed by the clamp 20 (see FIG. 10).
  • positioned corresponding to the several tube 131,132,133,134,135 was shifted and attached to the shaft member 222.
  • the arrangement of the long diameter portion of the cam 221 only the flow path of one tube of the plurality of tubes 131, 132, 133, 134, 135 is opened, and the flow of the other tubes The road is closed.
  • the air pump 140 is disposed inside the dialyzer main body 110, and reciprocates the diaphragm 137 by bringing air into and out of the chamber 136. More specifically, the air pump 140 is connected to the through hole on the side of the chamber 136 to which the tube 139 is not connected via a tube (not shown). Then, the air in the chamber 136 is suctioned by the air pump 140, thereby drawing the diaphragm 137 toward the air pump 140 and suctioning the dialysate from any of the tubes into the chamber 136. Further, in this state, air is introduced into the interior of the chamber 136 to push the diaphragm 137 toward the tube 139 to deliver the aspirated dialysate into the interior of the chamber 136. Thereby, a fixed amount (volume of the chamber 136) of the dialysate is aspirated or delivered.
  • the cassette lid portion 112 is attached to the dialysis device main body 110 so as to be openable and closable, and covers the flow path opening / closing mechanism 1.
  • the pressing member 23 for pressing the tube in the flow path opening / closing mechanism 1 is attached to the inner surface of the cassette lid portion 112 as described above.
  • the operation unit 150 includes a liquid crystal panel and various operation buttons.
  • the liquid crystal panel displays various information such as the flow rate of the dialysate.
  • the peritoneal dialysis apparatus 100 When the peritoneal dialysis apparatus 100 is used, first, as shown in FIG. 4, the liquid feeding / draining cassette 130 is attached to the flow path opening / closing mechanism 1. Next, the heating / use dialysate bag 101, the replacement dialysate bag 102, the concentration change dialysate bag 103, and the plurality of tubes 131, 132, 133, and 135 of the liquid feeding / draining cassette 130 are drained, respectively. Connect to the bag 104 and perform priming (see FIG. 2). Thereafter, the tube 134 is connected to the abdomen of the patient P and dialysis is started.
  • the air pump 140 is opened with the flow path of the predetermined tube (for example, the tube 131) opened by the flow path opening / closing mechanism 1 and the flow path of the other tubes closed.
  • the dialysate in this case, the dialysate contained in the heating dialysate bag 101
  • the flow path opening / closing mechanism 1 is operated to change the tube which opens the flow path (for example, the flow path of the tube 134 is opened and the flow path of the other tubes is closed).
  • Air is delivered to the interior of the chamber 136 (in this case, the delivery of the dialysate into the peritoneal cavity of the patient P).
  • a fixed amount (volume of the chamber 136) of the dialysate is aspirated and delivered.
  • the dialysate is sent to the abdominal cavity of the patient P (liquid transfer step), the abdominal cavity of the patient P Of the dialysate (drainage) from the drainage and drainage of the collected dialysate (drainage) to the drainage bag 104 (draining step), dialysis from the dialysate bag 102 for replenishment to the dialysate bag for heating 101 Refilling of the fluid and replacement of the dialysate from the concentration change dialysate bag 103 to the heating dialysate bag 101 are performed.
  • Clamping part 20 which opens / closes the flow path of the tube by advancing / retracting the pressing member 21 in the flow path opening / closing mechanism 1 in the vertical direction, and a guide member 30 which is disposed in the vicinity of the clamp part 20 and regulates the position of the tube.
  • the guide member 30 is configured to include the groove 32 which extends in the vertical direction and has a width D1 which is equal to or less than the outer diameter D2 of the tube.
  • the tube when the tube is pressed by the clamp unit 20 by arranging the guide member 30 in the vicinity of the clamp unit 20 and configuring the width D1 of the groove 32 extending in the vertical direction to be equal to or less than the outer diameter D2 of the tube In the groove 32, the tube can be restricted from spreading in the horizontal direction intersecting the direction (vertical direction) pressed by the clamp 20. Thereby, when the pressing of the tube by the clamp unit 20 is released, the horizontal expansion in the groove 32 is restricted by the tension (force applied to the closing side in the horizontal direction) generated in the tube. The restoring force of the portion pressed in the direction can be assisted.
  • the flow path can be pressed accurately when closing the flow path by the clamp portion 20, so that the liquid leaks out in the state where the flow path is closed.
  • the groove 32 in the vicinity of the clamp 20 and holding the tube by the groove 32, when pressing the tube by the clamp 20 (pressing member 21), the position of the tube at the pressed portion is Since it is possible to prevent the displacement (the tube escapes from the pressing member 21), the flow passage can be suitably closed by the pressing member 21.
  • the width D1 of the groove 32 is smaller than the outer diameter D2 of the tube.
  • the guide member 30 was arrange
  • the tube can be restricted from spreading in the horizontal direction on both sides of the portion of the tube pressed by the clamp portion 20, so that the resilience of the tube can be further improved when the press is released.
  • the flow path opening / closing mechanism 1 is configured to include the plurality of clamp portions 20, and the guide member 30 is configured to include the plurality of groove portions 32 disposed corresponding to the plurality of clamp portions 20. Thereby, the flow path of the liquid which circulates a plurality of tubes 131, 132, 133, 134, and 135 can be suitably opened and closed.
  • the peritoneal dialysis device 100 is configured to include the flow path opening / closing mechanism 1 of the present embodiment. Therefore, even when the temperature of the use environment of the peritoneal dialysis device 100 is low, when the flow path is opened from the closed state of the flow path, the flow path can be less likely to be blocked due to the deformation of the tube. Therefore, it is possible to realize the peritoneal dialysis device 100 which can perform liquid feeding and drainage more suitably.
  • the flow path opening / closing mechanism 1 is configured to include the five clamp portions 20 that open and close the flow paths of the five tubes, but the present invention is not limited thereto. That is, the flow path opening / closing mechanism may be configured to include four or less clamp portions 20, and may be configured to include six or more clamp portions.
  • the liquid feeding / draining cassette 130 is configured to include the chamber 136 and the diaphragm 137 to realize fixed amount of liquid feeding / liquid feeding, but the present invention is not limited thereto. That is, the liquid feeding / draining cassette may be configured to include a cylinder and a piston.
  • the flow-path opening-and-closing mechanism 1 was applied to the peritoneal dialysis apparatus 100 in this embodiment, it does not restrict to this. That is, the flow path opening / closing mechanism may be applied to an apparatus that causes a tube to flow a liquid different from the dialysate.

Abstract

The present invention provides: a flow passage opening/closing mechanism in which clogging of a flow passage due to deformation of tube does not easily occur; and a peritoneum dialysis device provided with the flow passage opening/closing mechanism. This flow passage opening/closing mechanism 1, which opens/closes a flow passage for a liquid formed inside a flexible tube, is provided with: a clamp part 20 which has pressing members 21 that can press the tube, and a driving mechanism 22 that moves the pressing members 21 forward/backward in a first direction, and which closes the flow passage by moving the pressing members 21 forward and opens the flow passage by moving the pressing members 21 backward; and guide members 30 that restrict the position of the tube in the vicinity of the clamp part 20, wherein the guide members 30 are each provided with a guide member body 31, and groove parts 32 which extend in the first direction in the guide member body 31, are each formed to have a width D1 equal to or smaller than the outer diameter D2 of the tube, and clamp the tube in a second direction crossing the first direction.

Description

流路開閉機構及び該流路開閉機構を備える腹膜透析装置Flow path opening / closing mechanism and peritoneal dialysis device provided with the flow path opening / closing mechanism
 本発明は、可撓性を有するチューブの内部に形成された液体の流路を開閉する流路開閉機構、及び該流路開閉機構を備える腹膜透析装置に関する。 The present invention relates to a flow path opening / closing mechanism for opening / closing a flow path of a liquid formed inside a flexible tube, and a peritoneal dialysis device provided with the flow path opening / closing mechanism.
 従来、患者の腹腔内に透析液を注入し、所定時間経過後に注入した透析液を排出することで、血液中に含まれる老廃物等を体外に排出する腹膜透析装置が提案されている(例えば、特許文献1参照)。このような腹膜透析装置では、透析液を収容する透析液バッグから所定量の透析液を吸引した後、この吸引された透析液を腹腔内に供給する送液工程、及び腹腔内から所定量の透析液(排液)を吸引した後、この吸引された透析液(排液)を排液バッグに排出する排液工程が、それぞれ繰り返し行われる。 Conventionally, there has been proposed a peritoneal dialysis apparatus that discharges wastes and the like contained in blood from the body by injecting the dialysate into the abdominal cavity of a patient and discharging the dialysate injected after a predetermined time has elapsed (for example, , Patent Document 1). In such a peritoneal dialysis apparatus, after a predetermined amount of dialysate is aspirated from a dialysate bag containing dialysate, a step of feeding the aspirated dialysate into the abdominal cavity, and a predetermined amount of the peritoneal cavity After suctioning the dialysate (drainage), the drainage step of draining the suctioned dialysate (drainage) to the drainage bag is repeated respectively.
 上記送液工程及び排液工程を行うための構成として、腹膜透析装置は、一端側が透析液バッグや排液バッグに接続される複数本の可撓性を有するチューブ、これら複数本のチューブの他端側に接続されるチャンバ、及びこのチャンバの内部を区画するダイヤフラム(隔膜)、を備える送液・排液カセットと、この送液・排液カセットの複数本のチューブを押圧して流路を閉止し押圧を解除することで流路を開放する流路開閉機構と、チャンバの内部に空気を出し入れすることでダイヤフラムを往復させて定量の透析液を吸引又は送出するエアポンプと、を備える。 As a configuration for performing the liquid transfer step and the drain step, the peritoneal dialysis device has a plurality of flexible tubes each having one end connected to the dialysate bag or the drain bag, and a plurality of tubes other than the plurality of tubes. A liquid feeding / draining cassette comprising a chamber connected to the end side and a diaphragm (diaphragm) partitioning the inside of the chamber, and a plurality of tubes of this liquid feeding / draining cassette are pressed to A flow path opening / closing mechanism that opens the flow path by closing and releasing the pressure, and an air pump that reciprocates the diaphragm by drawing air into and out of the chamber to suck or deliver a fixed amount of dialysate.
特開2006-181386号公報JP, 2006-181386, A
 ところで、流路開閉機構においては、可撓性を有するチューブを所定方向に押圧することでチューブを潰すように変形させて流路を閉止する。そのため、例えば、腹膜透析装置の使用環境の温度が低い場合には、流路を閉止した状態から流路を開放した場合に、変形したチューブの形状が復元されるまでに時間を要し、腹膜透析装置により流路が閉塞したと誤検知されてしまう場合があった。また、流路を開放した場合におけるチューブの形状の復元性が遅れることに起因して、透析液の送液・排液にかかる時間が長くなってしまうとの問題もあった。 By the way, in the flow path opening / closing mechanism, the flexible tube is deformed in a predetermined direction so as to crush the tube and the flow path is closed. Therefore, for example, when the temperature of the use environment of the peritoneal dialysis device is low, it takes time to restore the shape of the deformed tube when the flow passage is opened from the closed state of the flow passage, In some cases, the dialysis device erroneously detects that the flow path is blocked. In addition, there is also a problem that the time taken for liquid transfer / drainage of the dialysate is prolonged due to the delay in the restoration of the shape of the tube when the flow path is opened.
 従って、本発明は、チューブが変形することに起因する流路の閉塞が生じにくい流路開閉機構及び該流路開閉機構を備える腹膜透析装置を提供することを目的とする。 Accordingly, an object of the present invention is to provide a flow path opening / closing mechanism that is less likely to cause blockage of the flow path due to deformation of the tube, and a peritoneal dialysis device provided with the flow path opening / closing mechanism.
 本発明は、可撓性を有するチューブの内部に形成された液体の流路を開閉させる流路開閉機構であって、前記チューブを押圧可能な押圧部材、及び該押圧部材を第1方向に進退させる駆動機構を有し、該押圧部材を前進させることで前記流路を閉止し、該押圧部材を後退させることで前記流路を開放するクランプ部と、前記クランプ部の近傍において前記チューブの位置を規制するガイド部材と、を備え、前記ガイド部材は、ガイド部材本体と、前記ガイド部材本体において前記第1方向に延びると共に前記チューブの外径以下の幅に形成され、該チューブを前記第1方向に交差する第2方向に挟持する溝部と、を備える流路開閉機構に関する。 The present invention is a flow path opening / closing mechanism that opens and closes a flow path of a liquid formed inside a flexible tube, and a pressing member capable of pressing the tube, and advancing and retracting the pressing member in a first direction A drive mechanism for closing the flow path by advancing the pressing member and a clamp portion for opening the flow path by retracting the pressing member, and a position of the tube in the vicinity of the clamp portion And the guide member is formed to have a width equal to or less than the outer diameter of the tube and extends in the first direction in the guide member body and the guide member body. The present invention relates to a flow path opening / closing mechanism provided with a groove portion that holds in a second direction that intersects the direction.
 また、前記溝部の幅は、前記チューブの外径よりも小さいことが好ましい。 Preferably, the width of the groove is smaller than the outer diameter of the tube.
 また、前記ガイド部材は、前記チューブにおける前記クランプ部の近傍の一端側及び他端側に配置されることが好ましい。 Moreover, it is preferable that the said guide member is arrange | positioned at the one end side and the other end side in the vicinity of the said clamp part in the said tube.
 また、流路開閉機構は、複数の前記チューブに対応して配置される複数の前記クランプ部を備え、前記ガイド部材は、複数の前記クランプ部に対応して配置される複数の前記溝部を有することが好ましい。 In addition, the flow path opening / closing mechanism includes a plurality of clamps disposed corresponding to a plurality of tubes, and the guide member has a plurality of grooves disposed corresponding to a plurality of clamps. Is preferred.
 また、本発明は、上述の流路開閉機構と、一端側がそれぞれ透析液供給源又は透析液送出先に接続される複数の前記チューブ、該チューブの他端側に接続されるチャンバ、及びチャンバの内部を区画するダイヤフラムを備える送液・排液カセットと、前記チャンバの内部に空気を出し入れすることで前記ダイヤフラムを往復させて定量の透析液を吸引又は送出するエアポンプと、を備える腹膜透析装置に関する。 Further, according to the present invention, there is provided the flow channel opening / closing mechanism described above, a plurality of the tubes each having one end connected to the dialysate supply source or the dialysate delivery destination, a chamber connected to the other end of the tube, and The present invention relates to a peritoneal dialysis device including a liquid feeding / draining cassette provided with a diaphragm that divides the inside, and an air pump that reciprocates the diaphragm by drawing air in and out of the chamber to aspirate or deliver a fixed amount of dialysate. .
 本発明によれば、チューブが変形することに起因する流路の閉塞が生じにくい流路開閉機構及び該流路開閉機構を備える腹膜透析装置を提供できる。 According to the present invention, it is possible to provide a flow path opening / closing mechanism that is less likely to cause blockage of the flow path due to deformation of the tube, and a peritoneal dialysis device provided with the flow path opening / closing mechanism.
本発明の一実施形態に係る流路開閉機構を備える腹膜透析装置を示す斜視図である。It is a perspective view showing a peritoneal dialysis device provided with a channel opening and closing mechanism concerning one embodiment of the present invention. 本実施形態の腹膜透析装置の送液・排液カセットの構成を示す図である。It is a figure which shows the structure of the liquid feeding * drainage cassette of the peritoneal dialysis apparatus of this embodiment. 図1に示す腹膜透析装置における流路開閉機構部分の拡大図である。It is an enlarged view of the flow-path opening-and-closing mechanism part in the peritoneal dialysis apparatus shown in FIG. 送液・排液カセットが流路開閉機構に取り付けられた状態を示す斜視図である。It is a perspective view which shows the state in which the liquid feeding / drainage cassette was attached to the flow-path opening-and-closing mechanism. 送液・排液カセットが流路開閉機構に取り付けられた状態を示す平面図である。It is a top view which shows the state in which the liquid feeding * drainage cassette was attached to the flow-path opening / closing mechanism. 流路開閉機構のクランプ部の構成を示す平面図である。It is a top view which shows the structure of the clamp part of a flow-path opening-and-closing mechanism. クランプ部の動作を模式的に示す図であり、図6のX-X線断面に対応する図である。図7(a)は、チューブの流路が閉止された状態を示し、図7(b)は、チューブの流路が開放された状態を示す。FIG. 7 is a view schematically showing an operation of a clamp unit, which corresponds to a cross section along line XX in FIG. 6; FIG. 7 (a) shows a state in which the flow path of the tube is closed, and FIG. 7 (b) shows a state in which the flow path of the tube is opened. クランプ部の動作を模式的に示す図であり、図6のY-Y線断面に対応する図である。図8(a)は、チューブの流路が閉止された状態を示し、図8(b)は、チューブの流路が開放された状態を示す。FIG. 7 is a view schematically showing an operation of a clamp unit, and a view corresponding to a cross section along line YY in FIG. 6; FIG. 8 (a) shows a state in which the flow path of the tube is closed, and FIG. 8 (b) shows a state in which the flow path of the tube is opened. ガイド部材の溝部にチューブが挟持された状態を示す正面図である。It is a front view which shows the state by which the tube was clamped by the groove part of the guide member. 本実施形態の流路開閉機構によりチューブの流路が閉止された状態を示す斜視図である。It is a perspective view which shows the state by which the flow path of the tube was closed by the flow-path opening-and-closing mechanism of this embodiment.
 以下、本発明の流路開閉機構及び腹膜透析装置の好ましい一実施形態について、図面を参照しながら説明する。
 本実施形態の流路開閉機構1は、図1に示すように、腹膜透析装置100に適用される。まず、腹膜透析装置100の構成につき、説明する。
Hereinafter, a preferred embodiment of the flow path opening / closing mechanism and the peritoneal dialysis device of the present invention will be described with reference to the drawings.
The flow path opening / closing mechanism 1 of the present embodiment is applied to a peritoneal dialysis device 100, as shown in FIG. First, the configuration of the peritoneal dialysis device 100 will be described.
 腹膜透析装置100は、図1及び図2に示すように、透析装置本体110と、透析液バッグを収容して加温する加温部120と、この加温部120を覆う加温部蓋部111と、一定量の透析液を吸引及び送出する送液・排液カセット130(図2参照)と、送液・排液カセット130の流路を開閉する流路開閉機構1と、送液・排液カセット130を動作させるエアポンプ140と、流路開閉機構1を覆うカセット蓋部112と、操作部150と、を備える。 As shown in FIGS. 1 and 2, the peritoneal dialysis apparatus 100 includes a dialysis apparatus main body 110, a heating unit 120 for storing and heating a dialysate bag, and a heating unit cover that covers the heating unit 120. 111, a liquid feeding / draining cassette 130 (see FIG. 2) for sucking and feeding a fixed amount of dialysate, a flow path opening / closing mechanism 1 for opening / closing a flow path of liquid feeding / draining cassette 130, liquid feeding The air pump 140 for operating the drainage cassette 130, the cassette lid 112 covering the flow path opening / closing mechanism 1, and the operation unit 150 are provided.
 透析装置本体110は、腹膜透析装置100の外形を構成する。
 加温部120は、透析装置本体110の上面部に配置される。加温部120は、透析液が収容された透析液バッグを収納する収納部121と、加温用透析液バッグを加温する加温機構(図示せず)と、を備える。加温部120は、加温機構により、収納部121に収納された加温用透析液バッグ(透析液)を所定の温度に加温する。加温部120において加温される透析液の温度は、温度センサ123により測定される。
 加温部蓋部111は、透析装置本体110に対して開閉可能に取り付けられ、加温部120を覆う。
The dialysis device body 110 constitutes the outer shape of the peritoneal dialysis device 100.
The heating unit 120 is disposed on the upper surface of the dialysis device body 110. The heating unit 120 includes a storage unit 121 for storing the dialysate bag in which the dialysate is stored, and a heating mechanism (not shown) for heating the dialysate bag for heating. The heating unit 120 heats the heating dialysate bag (dialysate) stored in the storage unit 121 to a predetermined temperature by the heating mechanism. The temperature of the dialysate heated in the heating unit 120 is measured by the temperature sensor 123.
The heating unit lid 111 is attached to the dialysis device main body 110 so as to be openable and closable, and covers the heating unit 120.
 送液・排液カセット130は、図2に示すように、複数本のチューブ131,132,133,134,135と、チャンバ136と、このチャンバ136の内部に配置されるダイヤフラム137と、複数本のチューブ131,132,133,134,135を固定する固定部材138と、を備える。
 複数本のチューブ131,132,133,134,135は、可撓性を有する合成樹脂(例えば、軟質のポリ塩化ビニル)により構成される。これらチューブ131,132,133,134,135の一端側は、それぞれ、透析液供給源(後述の加温用透析液バッグ101、補充用透析液バッグ102、濃度変更用透析液バッグ103)又は透析液送出先(患者Pの腹腔内、排液バッグ104)に接続される。
As shown in FIG. 2, the liquid feeding / draining cassette 130 includes a plurality of tubes 131, 132, 133, 134, 135, a chamber 136, and a plurality of diaphragms 137 disposed inside the chamber 136. And a fixing member 138 for fixing the tubes 131, 132, 133, 134, and 135 of the above.
The plurality of tubes 131, 132, 133, 134, and 135 are made of a flexible synthetic resin (for example, soft polyvinyl chloride). One end of each of the tubes 131, 132, 133, 134, and 135 is supplied with a dialysate supply source (a dialysate bag 101 for heating, a dialysate bag 102 for replenishment, a dialysate bag 103 for concentration change) or dialysis It is connected to a fluid delivery destination (intraperitoneal cavity of patient P, drainage bag 104).
 本実施形態では、チューブ131は、加温部120に収納された加温用透析液バッグ101に接続され、加温ラインL1の一部又は全部(以下同様)を構成する。チューブ132は、補充用透析液バッグ102(本実施形態では、3つの補充用透析液バッグ102)に接続され、補充用ラインL2を構成する。チューブ133は、補充用透析液バッグ102に収容された透析液とは異なる濃度の透析液が収容された濃度変更用透析液バッグ103に接続され、濃度変更ラインL3を構成する。チューブ134は、患者Pの腹腔内に接続され、腹膜ラインL4を構成する。チューブ135は、排液を収容する排液バッグ104に接続され、排液ラインL5を構成する。
 尚、それぞれのチューブは、直接又はコネクタを介してバッグ等に接続される。
In the present embodiment, the tube 131 is connected to the heating dialysate bag 101 stored in the heating unit 120, and constitutes a part or all of the heating line L1 (the same applies to the following). The tube 132 is connected to the replacement dialysate bag 102 (in this embodiment, three replacement dialysate bags 102), and constitutes a replacement line L2. The tube 133 is connected to the concentration change dialysate bag 103 containing dialysate having a concentration different from that of the dialysate contained in the replacement dialysate bag 102, and constitutes a concentration change line L3. The tube 134 is connected to the peritoneal cavity of the patient P and constitutes a peritoneal line L4. The tube 135 is connected to a drainage bag 104 for containing drainage, and constitutes a drainage line L5.
Each tube is connected to a bag or the like directly or via a connector.
 チャンバ136は、硬質の合成樹脂(例えば、硬質のポリ塩化ビニル)により構成され、所定の容量(例えば、100ml)に形成される。本実施形態では、チャンバ136は、2つの同形の球面の一部が貼り合わされた形状に形成される。チャンバ136の2つの球面の中央には、それぞれ、チャンバ136の内部と外部とを連通させる貫通穴136aが形成される。一方の球面の貫通穴136aには、複数本のチューブ131,132,133,134,135の他端側が接続される。より詳細には、複数本のチューブ131,132,133,134,135の他端側は、1本のチューブ139に集合されており、この集合された1本のチューブ139がチャンバ136の一方の球面に形成された貫通穴136aに接続される。 The chamber 136 is made of a hard synthetic resin (for example, hard polyvinyl chloride) and is formed to a predetermined volume (for example, 100 ml). In the present embodiment, the chamber 136 is formed in a shape in which parts of two identical spherical surfaces are bonded. At the centers of the two spherical surfaces of the chamber 136, through holes 136a for communicating the inside and the outside of the chamber 136 are formed, respectively. The other end side of the plurality of tubes 131, 132, 133, 134, 135 is connected to one spherical through hole 136a. More specifically, the other ends of the plurality of tubes 131, 132, 133, 134, 135 are assembled into a single tube 139, and the assembled single tube 139 is one of the chambers 136. It is connected to a through hole 136a formed in a spherical surface.
 ダイヤフラム137は、弾性を有する膜部材により構成され、チャンバ136の内部を区画する。 The diaphragm 137 is formed of an elastic membrane member and defines the inside of the chamber 136.
 固定部材138は、矩形の枠状部138aと、一端部が枠状部138aに接続され棒状に延びる棒状部138bと、を備える。枠状部138aには、複数本のチューブ131,132,133,134,135が互いに平行に配置された状態でこれらのチューブ131,132,133,134,135を固定する複数の固定溝138c(図2参照)が形成されており、これら固定溝にチューブ131,132,133,134,135を固定することで、チューブ131,132,133,134,135が枠状部138aに固定される。棒状部138bは、他端側がチャンバ136に連結されると共に、チューブ131,132,133,134,135の他端側において集合された1本のチューブ139を支持する。 The fixing member 138 includes a rectangular frame 138a, and a rod 138b having one end connected to the frame 138a and extending like a rod. A plurality of fixing grooves 138c for fixing the tubes 131, 132, 133, 134, 135 in a state where the plurality of tubes 131, 132, 133, 134, 135 are arranged in parallel to each other in the frame portion 138a 2) are formed, and by fixing the tubes 131, 132, 133, 134, and 135 in these fixing grooves, the tubes 131, 132, 133, 134, and 135 are fixed to the frame portion 138a. The rod portion 138 b is connected to the chamber 136 at the other end, and supports one tube 139 collected at the other end of the tubes 131, 132, 133, 134, 135.
 流路開閉機構1は、図1及び図3に示すように、透析装置本体110の上面に配置される。この流路開閉機構1には、図3~図5に示すように、上述の送液・排液カセット130が取り付けられる。流路開閉機構1は、送液・排液カセット130の複数本のチューブ131,132,133,134,135の流路を開閉する。 The flow path opening / closing mechanism 1 is disposed on the upper surface of the dialysis device main body 110 as shown in FIGS. 1 and 3. As shown in FIGS. 3 to 5, the above-mentioned liquid feeding / draining cassette 130 is attached to the flow path opening / closing mechanism 1. The flow path opening / closing mechanism 1 opens / closes the flow path of the plurality of tubes 131, 132, 133, 134, 135 of the liquid feeding / draining cassette 130.
 流路開閉機構1は、クランプ部20と、ガイド部材30と、を備える。
 クランプ部20は、図6及び図7に示すように、チューブを押圧する押圧部材21と、この押圧部材21を進退させる駆動機構22と、チューブを挟んで押圧部材21の反対側に配置される押さえ部材23と、を備える。
The flow path opening / closing mechanism 1 includes a clamp unit 20 and a guide member 30.
The clamp part 20 is arrange | positioned on the other side of the press member 21 which pinches | interposes a tube between the press member 21 which presses a tube, the drive mechanism 22 which makes this press member 21 advance / retract, and a tube, as shown in FIG.6 and FIG.7. And a pressing member 23.
 本実施形態では、クランプ部20は、5本のチューブ131,132,133,134,135それぞれに対応して5セット配置される。より詳細には、図3~図6に示すように、本実施形態では、クランプ部20は、2列に配置され、一方の列(図5における右側の列)には、チューブ131,135を開閉するクランプ部20が配置され、他方の列(図5における左側の列)には、チューブ132,133,134を開閉するクランプ部20が配置される。 In the present embodiment, five sets of clamp portions 20 are arranged corresponding to the five tubes 131, 132, 133, 134, and 135, respectively. More specifically, as shown in FIGS. 3 to 6, in the present embodiment, the clamp portions 20 are arranged in two rows, and in one row (the right row in FIG. 5), the tubes 131 and 135 are provided. The clamp part 20 which opens and closes is arrange | positioned, and the clamp part 20 which opens and closes tube 132,133,134 is arrange | positioned in the other row (row on the left side in FIG. 5).
 押圧部材21は、図3に示すように、先端部(上端部)がチューブの幅(外径)よりもわずかに広い幅を有すると共に尖った(厚さの薄い)形状に形成される。押圧部材21は、チューブの下方に、先端部の幅方向がチューブの幅方向に沿うように配置される。 As shown in FIG. 3, the pressing member 21 is formed in a pointed (thin) shape with a tip (upper end) having a width slightly larger than the width (outside diameter) of the tube. The pressing member 21 is disposed below the tube so that the width direction of the tip extends along the width direction of the tube.
 駆動機構22は、図6及び図7に示すように、カム221と、このカム221に連結され回転軸となる軸部材222と、この軸部材222を回転させるモータ223と、を備える。本実施形態では、駆動機構22は、2列に配置されたクランプ部20に対応して、2本の軸部材222及びモータ223を含んで構成される。そして、一方の列(図6における右側の列)の軸部材222に、チューブ131,135に対応する押圧部材21を上下方向(第1方向)に移動させるカム221が取り付けられ、他方の列(図6における左側の列)の軸部材222に、チューブ132,133,134に対応する押圧部材21を上下方向に移動させるカム221が取り付けられる。また、1本の軸部材222に取り付けられる複数のカム221は、互いに長径部分の位置がずれるように配置される。 As shown in FIGS. 6 and 7, the drive mechanism 22 includes a cam 221, a shaft member 222 connected to the cam 221 and serving as a rotation shaft, and a motor 223 for rotating the shaft member 222. In the present embodiment, the drive mechanism 22 is configured to include two shaft members 222 and a motor 223 corresponding to the clamp portions 20 arranged in two rows. The cam 221 for moving the pressing member 21 corresponding to the tubes 131 and 135 in the vertical direction (first direction) is attached to the shaft member 222 of one row (the right row in FIG. 6), and the other row The cam 221 for moving the pressing member 21 corresponding to the tubes 132, 133 and 134 in the vertical direction is attached to the shaft member 222 of the left row in FIG. Further, the plurality of cams 221 attached to one shaft member 222 are arranged such that the positions of the major diameter portions are mutually offset.
 以上の駆動機構22によれば、モータ223を駆動して軸部材222を回転させることにより、カム221が回転する。そして、図7(a)及び図8(a)に示すように、カム221の長径部分により押圧部材21が押し上げられることで押圧部材21は上方に移動し、また、図7(b)及び図8(b)に示すように、カム221の短径部分により押圧部材21が押し上げられる力が解除されることで押圧部材21が下方に移動する。 According to the drive mechanism 22 described above, the cam 221 is rotated by driving the motor 223 to rotate the shaft member 222. Then, as shown in FIGS. 7A and 8A, the pressing member 21 is moved upward by the pressing member 21 being pushed up by the long diameter portion of the cam 221, and FIGS. 7B and 7C. As shown in FIG. 8 (b), the pressing member 21 is moved downward by releasing the force with which the pressing member 21 is pushed up by the short diameter portion of the cam 221.
 押さえ部材23は、図7及び図8に示すように、チューブの上方に、押圧部材21に対向して配置される。本実施形態では、押さえ部材23は、図1に示すように、後述のカセット蓋部112の内面に取り付けられる。 The pressing member 23 is disposed above the tube so as to face the pressing member 21 as shown in FIGS. 7 and 8. In the present embodiment, as shown in FIG. 1, the pressing member 23 is attached to the inner surface of the cassette lid 112 described later.
 ガイド部材30は、図4及び図5に示すように、クランプ部20の近傍に配置され、チューブの位置を規制する。より具体的には、ガイド部材30は、流路開閉機構1に取り付けられた送液・排液カセット130の複数本のチューブ131,132,133,134,135それぞれにおけるクランプ部20(押圧部材21)の両側に配置される。本実施形態では、クランプ部20は2列に配置されているため、ガイド部材30は、4列に配置される。 The guide member 30 is disposed in the vicinity of the clamp unit 20 as shown in FIGS. 4 and 5 and regulates the position of the tube. More specifically, the guide member 30 is a clamp portion 20 (pressing member 21 in each of the plurality of tubes 131, 132, 133, 134, 135 of the liquid feeding / draining cassette 130 attached to the flow path opening / closing mechanism 1). Placed on both sides of In the present embodiment, since the clamp portions 20 are arranged in two rows, the guide members 30 are arranged in four rows.
 ガイド部材30は、図3~図5に示すように、矩形の板状のガイド部材本体31と、このガイド部材本体31に形成される溝部32と、を備える。
 ガイド部材本体31は、長手方向がチューブの延びる方向に交差(直交)する方向に沿うように配置される。また、ガイド部材30は、板面が鉛直方向に沿うように配置される。
The guide member 30 includes a rectangular plate-like guide member main body 31 and a groove 32 formed in the guide member main body 31, as shown in FIGS.
The guide member main body 31 is disposed so that the longitudinal direction intersects (orthogonal to) the extending direction of the tube. Moreover, the guide member 30 is arrange | positioned so that a plate surface may follow a perpendicular direction.
 溝部32は、ガイド部材本体31において上側に位置する側縁から上下方向(第1方向)に延びて形成される。また、溝部32の幅D1は、図9に示すように、張力等がかかっていない状態(自然状態)におけるチューブの外径D2以下の幅の部分を有する大きさに形成される。チューブは、この溝部32に押し込まれることで溝部32により上下方向(第1方向)に交差(直交)する水平方向(第2方向)に挟持され、位置が規制される。ここで、溝部32の幅D1とは、例えば、溝部32の幅が下方から上方に向かって異なる(拡径する)場合等には、溝部32のうちのチューブを挟持する部分における中央部の幅を示す。
 本実施形態では、溝部32の幅D1は、チューブの外径D2よりも小さい幅に形成される。具体的には、チューブの外径D2が5mmの場合、溝部32におけるチューブを挟持する部分の幅D1は、3.5mm~5mmであることが好ましく、4mm~4.5mmであることがより好ましい。
The groove portion 32 is formed to extend in the vertical direction (first direction) from a side edge located on the upper side in the guide member main body 31. Further, as shown in FIG. 9, the width D1 of the groove portion 32 is formed to have a portion having a width equal to or less than the outer diameter D2 of the tube in a non-tensioned state (natural state). The tube is held in the horizontal direction (second direction) intersecting (orthogonal) in the vertical direction (first direction) by the groove 32 by being pushed into the groove 32, and the position is regulated. Here, the width D1 of the groove 32 is, for example, the width of the central portion of the groove 32 in which the tube is held when the width of the groove 32 is different (expands in diameter) from the lower side to the upper side. Indicates
In the present embodiment, the width D1 of the groove 32 is formed to be smaller than the outer diameter D2 of the tube. Specifically, when the outer diameter D2 of the tube is 5 mm, the width D1 of the portion of the groove 32 that sandwiches the tube is preferably 3.5 mm to 5 mm, and more preferably 4 mm to 4.5 mm .
 本実施形態では、1つのガイド部材30には、5本のチューブ131,132,133,134,135に対応して5つの溝部32が形成される。即ち、1本のチューブは、4つのガイド部材30(溝部32)により位置が規制される。そして、そのうちの2つのガイド部材30(溝部32)がクランプ部20(押圧部材21)の近傍において、チューブを挟持している。
 ガイド部材30が配置される位置は、チューブの径によって影響されるが、上記の例(チューブ外径D2が5mm)の場合、クランプ部20から3.0mm~11.0mmの範囲であることが好ましく、5.0mm~9.0mmの範囲であることがより好ましい。ガイド部材30が配置される位置とクランプ部20との間の距離を上記範囲に設定することで、後述するように、ガイド部材30(溝部32)によりチューブの形状を好適に復元させられる。
In the present embodiment, five grooves 32 are formed in one guide member 30 corresponding to the five tubes 131, 132, 133, 134 and 135. That is, the position of one tube is restricted by the four guide members 30 (grooves 32). The two guide members 30 (grooves 32) among them hold the tube in the vicinity of the clamp 20 (pressing member 21).
The position where the guide member 30 is disposed is influenced by the diameter of the tube, but in the case of the above example (the tube outer diameter D2 is 5 mm), the range from 3.0 mm to 11.0 mm from the clamp portion 20 Preferably, the range is 5.0 mm to 9.0 mm. By setting the distance between the position where the guide member 30 is disposed and the clamp portion 20 in the above range, the shape of the tube can be suitably restored by the guide member 30 (the groove 32) as described later.
 以上の流路開閉機構1は、以下のように動作する。
 まず、流路開閉機構1に送液・排液カセット130を配置する。ここで、図4及び図5に示すように、5本のチューブ131,132,133,134,135は、それぞれ、クランプ部20の近傍(クランプ部20の両側)において、ガイド部材30の溝部32により位置が規制される。また、図9に示すように、溝部32におけるチューブを挟持する部分の幅D1は、チューブの外径D2よりも小さく形成されている。これにより、図10に示すように、溝部32において、チューブには、水平方向(第2方向)における閉じる側(図10の矢印方向)に力(テンション)が加えられる。
The flow path opening / closing mechanism 1 described above operates as follows.
First, the liquid feeding / draining cassette 130 is disposed in the flow path opening / closing mechanism 1. Here, as shown in FIGS. 4 and 5, the five tubes 131, 132, 133, 134, and 135 respectively have the groove portions 32 of the guide member 30 in the vicinity of the clamp portion 20 (both sides of the clamp portion 20). Position is restricted. Further, as shown in FIG. 9, the width D1 of the portion of the groove 32 for holding the tube is smaller than the outer diameter D2 of the tube. Thereby, as shown in FIG. 10, in the groove portion 32, a force (tension) is applied to the tube in the horizontal direction (second direction) on the closing side (arrow direction in FIG. 10).
 この状態において、駆動機構22を動作させる。即ち、モータ223を駆動して軸部材222を回転させることにより、カム221を回転させる。すると、図7(a)及び図8(a)に示すように、カム221の長径部分により押圧部材21が押し上げられることで押圧部材21は上方に移動し、チューブを上下方向(第1方向)に押圧する。これによりチューブの流路は閉止される(図10参照)。また、図7(b)及び図8(b)に示すように、更にカム221を回転させてカム221の短径部分が押圧部材21に対応する位置にくると、押圧部材21が押し上げられる力が解除され押圧部材21が下方に移動する。これにより、チューブの押圧が解除されて流路が開放される。 In this state, the drive mechanism 22 is operated. That is, by driving the motor 223 to rotate the shaft member 222, the cam 221 is rotated. Then, as shown in FIGS. 7A and 8A, the pressing member 21 is moved upward by the pressing member 21 being pushed up by the long diameter portion of the cam 221, and the tube is moved up and down (first direction). Press to. Thereby, the flow path of the tube is closed (see FIG. 10). Further, as shown in FIGS. 7B and 8B, when the cam 221 is further rotated and the short diameter portion of the cam 221 comes to a position corresponding to the pressing member 21, a force by which the pressing member 21 is pushed up. Is released and the pressing member 21 moves downward. Thereby, the pressure of the tube is released and the flow path is opened.
 ここで、本実施形態では、ガイド部材30をクランプ部20の近傍に配置し、かつ、溝部32の幅D1をチューブの外径D2以下に構成することで、クランプ部20によりチューブが押圧された場合に、溝部32において、チューブがクランプ部20により押圧される上下方向(第1方向)に交差する水平方向(第2方向)に広がることを規制できる(図10参照)。これにより、クランプ部20によるチューブの押圧が解除された場合に、溝部32において水平への広がりが規制されることによりチューブに生じるテンション(水平方向の閉じる側に付与される力)により、上下方向に押圧された部分の復元力をアシストできる。よって、押圧が解除された場合に速やかにチューブの形状が復元するので、チューブが変形することに起因する流路の閉塞を生じにくくできる。また、クランプ部20の近傍において溝部32によりチューブを挟持することで、クランプ部20により流路を閉止する場合に精度よく流路を押圧できる。 Here, in the present embodiment, the tube is pressed by the clamp unit 20 by arranging the guide member 30 in the vicinity of the clamp unit 20 and configuring the width D1 of the groove 32 to be equal to or less than the outer diameter D2 of the tube. In this case, in the groove 32, the tube can be restricted from spreading in the horizontal direction (second direction) intersecting with the vertical direction (first direction) pressed by the clamp 20 (see FIG. 10). Thereby, when the pressing of the tube by the clamp unit 20 is released, the horizontal expansion in the groove 32 is restricted by the tension (force applied to the closing side in the horizontal direction) generated in the tube, the vertical direction It can assist the restoring force of the part pressed by the Therefore, when the pressure is released, the shape of the tube is promptly restored, so it is possible to make it difficult to cause blocking of the flow passage due to deformation of the tube. In addition, by clamping the tube by the groove 32 in the vicinity of the clamp portion 20, when the flow path is closed by the clamp portion 20, the flow path can be pressed with high accuracy.
 また、本実施形態では、複数本のチューブ131,132,133,134,135に対応して配置されるカム221の長径部分の位置をずらして軸部材222に取り付けた。これにより、カム221の長径部分の配置を適宜設定することで、複数本のチューブ131,132,133,134,135のうちの1本のチューブの流路のみを開放し、他のチューブの流路を閉止させられる。 Moreover, in this embodiment, the position of the major-diameter part of the cam 221 arrange | positioned corresponding to the several tube 131,132,133,134,135 was shifted and attached to the shaft member 222. As shown in FIG. Thus, by appropriately setting the arrangement of the long diameter portion of the cam 221, only the flow path of one tube of the plurality of tubes 131, 132, 133, 134, 135 is opened, and the flow of the other tubes The road is closed.
 エアポンプ140は、図1に示すように、透析装置本体110の内部に配置され、チャンバ136の内部に空気を出し入れすることでダイヤフラム137を往復させる。より具体的には、エアポンプ140は、チューブ(図示せず)を介してチャンバ136におけるチューブ139が接続されていない側の貫通穴に接続される。そして、エアポンプ140によりチャンバ136の内部の空気を吸引することで、ダイヤフラム137をエアポンプ140側に引き寄せていずれかのチューブからチャンバ136の内部に透析液を吸引する。また、この状態において、チャンバ136の内部に空気を導入することで、ダイヤフラム137をチューブ139側に押し込んでチャンバ136の内部に吸引された透析液を送出する。これにより、一定量(チャンバ136の容積)の透析液が吸引又は送出される。 As shown in FIG. 1, the air pump 140 is disposed inside the dialyzer main body 110, and reciprocates the diaphragm 137 by bringing air into and out of the chamber 136. More specifically, the air pump 140 is connected to the through hole on the side of the chamber 136 to which the tube 139 is not connected via a tube (not shown). Then, the air in the chamber 136 is suctioned by the air pump 140, thereby drawing the diaphragm 137 toward the air pump 140 and suctioning the dialysate from any of the tubes into the chamber 136. Further, in this state, air is introduced into the interior of the chamber 136 to push the diaphragm 137 toward the tube 139 to deliver the aspirated dialysate into the interior of the chamber 136. Thereby, a fixed amount (volume of the chamber 136) of the dialysate is aspirated or delivered.
 カセット蓋部112は、透析装置本体110に対して開閉可能に取り付けられ、流路開閉機構1を覆う。このカセット蓋部112の内面には、上述のように、流路開閉機構1においてチューブを押さえる押さえ部材23が取り付けられる。 The cassette lid portion 112 is attached to the dialysis device main body 110 so as to be openable and closable, and covers the flow path opening / closing mechanism 1. The pressing member 23 for pressing the tube in the flow path opening / closing mechanism 1 is attached to the inner surface of the cassette lid portion 112 as described above.
 操作部150は、液晶パネル及び各種操作ボタンを含んで構成される。液晶パネルには、透析液の流量等の各種情報が表示される。 The operation unit 150 includes a liquid crystal panel and various operation buttons. The liquid crystal panel displays various information such as the flow rate of the dialysate.
 次に、以上の腹膜透析装置100の動作の一例につき説明する。
 腹膜透析装置100を使用する場合、まず、図4に示すように、送液・排液カセット130を流路開閉機構1に取り付ける。次いで、送液・排液カセット130の複数本のチューブ131,132,133,135を、それぞれ、加温用透析液バッグ101、補充用透析液バッグ102、濃度変更用透析液バッグ103、排液バッグ104に接続し、プライミングを行う(図2参照)。その後、チューブ134を患者Pの腹部に接続し、透析を開始する。
Next, an example of the operation of the above-described peritoneal dialysis apparatus 100 will be described.
When the peritoneal dialysis apparatus 100 is used, first, as shown in FIG. 4, the liquid feeding / draining cassette 130 is attached to the flow path opening / closing mechanism 1. Next, the heating / use dialysate bag 101, the replacement dialysate bag 102, the concentration change dialysate bag 103, and the plurality of tubes 131, 132, 133, and 135 of the liquid feeding / draining cassette 130 are drained, respectively. Connect to the bag 104 and perform priming (see FIG. 2). Thereafter, the tube 134 is connected to the abdomen of the patient P and dialysis is started.
 ここで、透析を行う場合には、流路開閉機構1により所定の1本のチューブ(例えば、チューブ131)の流路を開放し、他のチューブの流路を閉止した状態で、エアポンプ140によりチャンバ136の内部の空気を吸引することで、流路が開放されているチューブからチャンバ136の内部に透析液(この場合、加温用透析液バッグ101に収容された透析液)を吸引する。次いで、流路開閉機構1を操作して流路を開放するチューブを変更し(例えば、チューブ134の流路を開放し、他のチューブの流路を閉止)、この状態において、チャンバ136の内部に空気を導入することで、でチャンバ136の内部に吸引された透析液を送出(この場合、患者Pの腹腔内に透析液を送出)する。これにより、一定量(チャンバ136の容積)の透析液が吸引及び送出される。 Here, in the case of performing dialysis, the air pump 140 is opened with the flow path of the predetermined tube (for example, the tube 131) opened by the flow path opening / closing mechanism 1 and the flow path of the other tubes closed. By suctioning the air inside the chamber 136, the dialysate (in this case, the dialysate contained in the heating dialysate bag 101) is sucked into the chamber 136 from the tube whose flow path is opened. Then, the flow path opening / closing mechanism 1 is operated to change the tube which opens the flow path (for example, the flow path of the tube 134 is opened and the flow path of the other tubes is closed). Air is delivered to the interior of the chamber 136 (in this case, the delivery of the dialysate into the peritoneal cavity of the patient P). Thereby, a fixed amount (volume of the chamber 136) of the dialysate is aspirated and delivered.
 以上のように、流路開閉機構1により流路を開放するチューブ変更しながら上記操作を繰り返すことで、透析液の患者Pの腹腔内への送液(送液工程)、患者Pの腹腔内からの透析液(排液)の回収及び回収した透析液(排液)の排液バッグ104への排出(排液工程)、補充用透析液バッグ102から加温用透析液バッグ101への透析液の補充、並びに濃度変更用透析液バッグ103から加温用透析液バッグ101への透析液の補充等が行われる。 As described above, by repeating the above operation while changing the tube for opening the flow path by the flow path opening / closing mechanism 1, the dialysate is sent to the abdominal cavity of the patient P (liquid transfer step), the abdominal cavity of the patient P Of the dialysate (drainage) from the drainage and drainage of the collected dialysate (drainage) to the drainage bag 104 (draining step), dialysis from the dialysate bag 102 for replenishment to the dialysate bag for heating 101 Refilling of the fluid and replacement of the dialysate from the concentration change dialysate bag 103 to the heating dialysate bag 101 are performed.
 以上説明した本実施形態の流路開閉機構1及び腹膜透析装置100によれば、以下のような作用効果を奏する。 According to the flow path opening / closing mechanism 1 and the peritoneal dialysis device 100 of the present embodiment described above, the following effects can be obtained.
 (1)流路開閉機構1を、押圧部材21を上下方向に進退させてチューブの流路を開閉するクランプ部20と、このクランプ部20の近傍に配置されチューブの位置を規制するガイド部材30と、を含んで構成し、このガイド部材30を、上下方向に延びると共にチューブの外径D2以下の幅D1に形成される溝部32を含んで構成した。これにより、ガイド部材30をクランプ部20の近傍に配置し、かつ、上下方向に延びる溝部32の幅D1をチューブの外径D2以下に構成することで、クランプ部20によりチューブが押圧された場合に、溝部32において、チューブがクランプ部20により押圧される方向(上下方向)に交差する水平方向に広がることを規制できる。これにより、クランプ部20によるチューブの押圧が解除された場合に、溝部32において水平方向への広がりが規制されることによりチューブに生じるテンション(水平方向の閉じる側に付与される力)により、上下方向に押圧された部分の復元力をアシストできる。よって、押圧が解除された場合に速やかにチューブの形状が復元するので、チューブが変形することに起因する流路の閉塞を生じにくくできる。また、クランプ部20の近傍において溝部32によりチューブを挟持することで、クランプ部20により流路を閉止する場合に精度よく流路を押圧できるので、流路を閉止した状態において液体が漏れ出すことを防げる。即ち、クランプ部20の近傍に溝部32を配置し、この溝部32によりチューブを挟持することで、クランプ部20(押圧部材21)によりチューブを押圧する場合に、押圧される部分においてチューブの位置がずれてしまう(押圧部材21からチューブが逃げてしまう)ことを防げるので、押圧部材21により好適に流路を閉止できる。 (1) Clamping part 20 which opens / closes the flow path of the tube by advancing / retracting the pressing member 21 in the flow path opening / closing mechanism 1 in the vertical direction, and a guide member 30 which is disposed in the vicinity of the clamp part 20 and regulates the position of the tube. And the guide member 30 is configured to include the groove 32 which extends in the vertical direction and has a width D1 which is equal to or less than the outer diameter D2 of the tube. Thereby, when the tube is pressed by the clamp unit 20 by arranging the guide member 30 in the vicinity of the clamp unit 20 and configuring the width D1 of the groove 32 extending in the vertical direction to be equal to or less than the outer diameter D2 of the tube In the groove 32, the tube can be restricted from spreading in the horizontal direction intersecting the direction (vertical direction) pressed by the clamp 20. Thereby, when the pressing of the tube by the clamp unit 20 is released, the horizontal expansion in the groove 32 is restricted by the tension (force applied to the closing side in the horizontal direction) generated in the tube. The restoring force of the portion pressed in the direction can be assisted. Therefore, when the pressure is released, the shape of the tube is promptly restored, so it is possible to make it difficult to cause blocking of the flow passage due to deformation of the tube. Further, by holding the tube by the groove 32 in the vicinity of the clamp portion 20, the flow path can be pressed accurately when closing the flow path by the clamp portion 20, so that the liquid leaks out in the state where the flow path is closed. Can prevent That is, by arranging the groove 32 in the vicinity of the clamp 20 and holding the tube by the groove 32, when pressing the tube by the clamp 20 (pressing member 21), the position of the tube at the pressed portion is Since it is possible to prevent the displacement (the tube escapes from the pressing member 21), the flow passage can be suitably closed by the pressing member 21.
 (2)溝部32の幅D1を、チューブの外径D2よりも小さく構成した。これにより、溝部32においてチューブに対して水平方向により大きなテンションを生じさせられる。よって、(押圧部材21による)押圧が開放された場合におけるチューブの復元力を更に向上させられる。 (2) The width D1 of the groove 32 is smaller than the outer diameter D2 of the tube. As a result, in the groove 32, a greater tension can be generated in the horizontal direction with respect to the tube. Therefore, the restoring force of the tube when the pressure is released (by the pressing member 21) can be further improved.
 (3)ガイド部材30を、チューブにおけるクランプ部20の両側(一端側及び他端側)に配置した。これにより、チューブにおけるクランプ部20に押圧される部分の両側において、チューブが水平方向に広がることを規制できるので、押圧が開放された場合におけるチューブの復元力をより向上させられる。 (3) The guide member 30 was arrange | positioned at the both sides (one end side and the other end side) of the clamp part 20 in a tube. Thus, the tube can be restricted from spreading in the horizontal direction on both sides of the portion of the tube pressed by the clamp portion 20, so that the resilience of the tube can be further improved when the press is released.
 (4)流路開閉機構1を、複数のクランプ部20を含んで構成し、ガイド部材30を、複数のクランプ部20に対応して配置される複数の溝部32を含んで構成した。これにより、複数本のチューブ131,132,133,134,135を流通する液体の流路を好適に開閉させられる。 (4) The flow path opening / closing mechanism 1 is configured to include the plurality of clamp portions 20, and the guide member 30 is configured to include the plurality of groove portions 32 disposed corresponding to the plurality of clamp portions 20. Thereby, the flow path of the liquid which circulates a plurality of tubes 131, 132, 133, 134, and 135 can be suitably opened and closed.
 (5)腹膜透析装置100を、本実施形態の流路開閉機構1を含んで構成した。これにより、腹膜透析装置100の使用環境の温度が低い場合等でも、流路を閉止した状態から流路を開放した場合に、チューブが変形することに起因する流路の閉塞を生じにくくできる。よって、より好適に送液及び排液を行える腹膜透析装置100を実現できる。 (5) The peritoneal dialysis device 100 is configured to include the flow path opening / closing mechanism 1 of the present embodiment. Thereby, even when the temperature of the use environment of the peritoneal dialysis device 100 is low, when the flow path is opened from the closed state of the flow path, the flow path can be less likely to be blocked due to the deformation of the tube. Therefore, it is possible to realize the peritoneal dialysis device 100 which can perform liquid feeding and drainage more suitably.
 以上、本発明の流路開閉機構1及び腹膜透析装置100の好ましい一実施形態について説明したが、本発明は、上述した実施形態に制限されるものではなく、適宜変更が可能である。
 例えば、本実施形態では、流路開閉機構1を5本のチューブの流路を開閉する5つのクランプ部20を含んで構成したが、これに限らない。即ち、流路開閉機構を、4つ以下のクランプ部20を含んで構成してもよく、また6つ以上のクランプ部を含んで構成してもよい。
As mentioned above, although one preferable embodiment of the flow-path opening-closing mechanism 1 and the peritoneal dialysis apparatus 100 of this invention was described, this invention is not restrict | limited to embodiment mentioned above, It can change suitably.
For example, in the present embodiment, the flow path opening / closing mechanism 1 is configured to include the five clamp portions 20 that open and close the flow paths of the five tubes, but the present invention is not limited thereto. That is, the flow path opening / closing mechanism may be configured to include four or less clamp portions 20, and may be configured to include six or more clamp portions.
 また、本実施形態では、送液・排液カセット130を、チャンバ136と、ダイヤフラム137とを含んで構成して、定量の吸液・送液を実現したが、これに限らない。即ち、送液・排液カセットを、シリンダ及びピストンを含んで構成してもよい。 Further, in the present embodiment, the liquid feeding / draining cassette 130 is configured to include the chamber 136 and the diaphragm 137 to realize fixed amount of liquid feeding / liquid feeding, but the present invention is not limited thereto. That is, the liquid feeding / draining cassette may be configured to include a cylinder and a piston.
 また、本実施形態では、流路開閉機構1を、腹膜透析装置100に適用したが、これに限らない。即ち、流路開閉機構を、チューブにより透析液とは異なる液体を流通させる装置に適用してもよい。 Moreover, although the flow-path opening-and-closing mechanism 1 was applied to the peritoneal dialysis apparatus 100 in this embodiment, it does not restrict to this. That is, the flow path opening / closing mechanism may be applied to an apparatus that causes a tube to flow a liquid different from the dialysate.
 1 流路開閉機構
 20 クランプ部
 21 押圧部材
 22 駆動機構
 30 ガイド部材
 32 溝部
 130 送液・排液カセット
 131 チューブ
 132 チューブ
 133 チューブ
 134 チューブ
 135 チューブ
 136 チャンバ
 137 ダイヤフラム
 140 エアポンプ
DESCRIPTION OF SYMBOLS 1 flow-path opening-and-closing mechanism 20 clamp part 21 pressing member 22 drive mechanism 30 guide member 32 groove part 130 liquid feeding / drainage cassette 131 tube 132 tube 133 tube 134 tube 135 tube 136 chamber 137 diaphragm 140 air pump

Claims (5)

  1.  可撓性を有するチューブの内部に形成された液体の流路を開閉させる流路開閉機構であって、
     前記チューブを押圧可能な押圧部材、及び該押圧部材を第1方向に進退させる駆動機構を有し、該押圧部材を前進させることで前記流路を閉止し、該押圧部材を後退させることで前記流路を開放するクランプ部と、
     前記クランプ部の近傍において前記チューブの位置を規制するガイド部材と、を備え、
     前記ガイド部材は、
      ガイド部材本体と、
      前記ガイド部材本体において前記第1方向に延びると共に前記チューブの外径以下の幅に形成され、該チューブを前記第1方向に交差する第2方向に挟持する溝部と、を備える流路開閉機構。
    A flow path opening / closing mechanism for opening and closing a flow path of a liquid formed inside a flexible tube,
    The pressing member has a pressing member capable of pressing the tube, and a drive mechanism for advancing and retracting the pressing member in the first direction, and the flow passage is closed by advancing the pressing member and the pressing member is retracted. A clamp that opens the flow path,
    And a guide member that regulates the position of the tube in the vicinity of the clamp portion.
    The guide member is
    A guide member body,
    A channel opening / closing mechanism that extends in the first direction and has a width equal to or less than the outer diameter of the tube in the guide member main body and sandwiches the tube in a second direction intersecting the first direction.
  2.  前記溝部の幅は、前記チューブの外径よりも小さい請求項1に記載の流路開閉機構。 The flow path opening / closing mechanism according to claim 1, wherein a width of the groove portion is smaller than an outer diameter of the tube.
  3.  前記ガイド部材は、前記チューブにおける前記クランプ部の近傍の一端側及び他端側に配置される請求項1又は2に記載の流路開閉機構。 The flow path opening / closing mechanism according to claim 1 or 2, wherein the guide member is disposed at one end side and the other end side in the vicinity of the clamp portion in the tube.
  4.  複数の前記チューブに対応して配置される複数の前記クランプ部を備え、
     前記ガイド部材は、複数の前記クランプ部に対応して配置される複数の前記溝部を有する請求項1~3のいずれかに記載の流路開閉機構。
    A plurality of the clamps disposed corresponding to the plurality of tubes;
    The flow path opening / closing mechanism according to any one of claims 1 to 3, wherein the guide member has a plurality of the groove portions arranged corresponding to a plurality of the clamp portions.
  5.  請求項4に記載の流路開閉機構と、
     一端側がそれぞれ透析液供給源又は透析液送出先に接続される複数の前記チューブ、該チューブの他端側に接続されるチャンバ、及びチャンバの内部を区画するダイヤフラムを備える送液・排液カセットと、
     前記チャンバの内部に空気を出し入れすることで前記ダイヤフラムを往復させて定量の透析液を吸引又は送出するエアポンプと、を備える腹膜透析装置。
    The flow path opening / closing mechanism according to claim 4;
    A plurality of tubes each having one end connected to a dialysate supply source or a dialysate delivery destination, a chamber connected to the other end of the tube, and a liquid feeding / draining cassette provided with a diaphragm for dividing the inside of the chamber; ,
    And d) an air pump which sucks or delivers a fixed amount of dialysate by reciprocating the diaphragm by taking air into and out of the chamber.
PCT/JP2017/026163 2017-07-19 2017-07-19 Flow passage opening/closing mechanism, and peritoneum dialysis device provided with said flow passage opening/closing mechanism WO2019016904A1 (en)

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