WO2019004710A1 - Dispositif et procédé de mesure d'électroencéphalogramme et d'électrocardiogramme - Google Patents

Dispositif et procédé de mesure d'électroencéphalogramme et d'électrocardiogramme Download PDF

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WO2019004710A1
WO2019004710A1 PCT/KR2018/007245 KR2018007245W WO2019004710A1 WO 2019004710 A1 WO2019004710 A1 WO 2019004710A1 KR 2018007245 W KR2018007245 W KR 2018007245W WO 2019004710 A1 WO2019004710 A1 WO 2019004710A1
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electroencephalogram
electrocardiogram
electric signal
electrode
measurement device
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PCT/KR2018/007245
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English (en)
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Joong Woo Ahn
Yun Seo Ku
Hee Chan Kim
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Seoul National University R&Db Foundation
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/251—Means for maintaining electrode contact with the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A—HUMAN NECESSITIES
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    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
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    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/6815—Ear
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    • A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
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    • A—HUMAN NECESSITIES
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    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/725—Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
    • A—HUMAN NECESSITIES
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    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6844—Monitoring or controlling distance between sensor and tissue

Definitions

  • the present disclosure relates to an electroencephalogram and electrocardiogram measurement device and method for simultaneously measuring an electroencephalogram and an electrocardiogram of a user and for making sure that both an electroencephalogram and an electrocardiogram can be measured at the head of a user.
  • bio signals In living things including humans, various electric signals that may be generally referred to as bio signals are generated. These bio signals include electroencephalogram (EEG), electrocardiogram (ECG), ballistocardiogram (BCG), and photoplethysmogram (PPG). By analyzing these bio signals, it is possible to obtain various kinds of information about the state of a living thing.
  • EEG electroencephalogram
  • ECG electrocardiogram
  • BCG ballistocardiogram
  • PPG photoplethysmogram
  • the electroencephalogram and the electrocardiogram are signals that indicate the conditions of the brain and heart which are the most important organs indispensable to human survival. It can be said that among the various bio signals, the electroencephalogram and the electrocardiogram are of paramount importance.
  • the electroencephalogram is an electric signal generated by brain activity.
  • the electroencephalogram may be used to diagnose brain diseases such as epilepsy, stroke, brain tumor and the like. Recently, the electroencephalogram is used not only for diagnosing diseases but also for monitoring brain activities of subjects such as perception and cognitive ability tests and the like.
  • the electrocardiogram is an electric signal generated by the contraction and relaxation of the heart and used as data for interpreting the motion of the heart. By observing the electrocardiogram, it is possible to know the speed and steadiness of the heartbeat. This makes it possible to determine the occurrence of heart-related diseases such as myocardial infarction, angina pectoris, arrhythmia and the like.
  • the electroencephalogram is acquired from the head of the user, and the electrocardiogram is obtained from the chest of the user.
  • the electroencephalogram is acquired from the head of the user, and the electrocardiogram is obtained from the chest of the user.
  • bio signal measurement electrodes for head attachment and chest attachment. This may be become a cause of increasing the volume of the device, making the device configuration complex, and making it inconvenient for the user to wear the device.
  • Patent Document 1 Korean Patent Application Publication No. 10-2015-0133468 (published on November 30, 2015)
  • Embodiments of the present disclosure provide an electroencephalogram and electrocardiogram measurement device and method capable of simultaneously measuring an electroencephalogram and an electrocardiogram, limiting a measurement target body part of a user to a narrower region, simplifying components required for measurement and enabling a user to easily measure an electroencephalogram and an electrocardiogram.
  • an electroencephalogram and electrocardiogram measurement device includes a plurality of electrodes configured to detect electric signals from a head above a neck of a user and a control unit configured to obtain an electroencephalogram and an electrocardiogram of the user based on the detected electric signals.
  • control unit is configured to obtain the electroencephalogram and the electrocardiogram of the user based on an electric signal detected from an electrode among the plurality of electrodes.
  • the plurality of electrodes includes a reference electrode, an active electrode and a ground electrode.
  • the control unit is configured to obtain the electroencephalogram based on a difference between a first electric signal detected from the reference electrode and a second electric signal detected from the active electrode, and obtain the electrocardiogram based on a difference between the second electric signal and a third electric signal detected from the ground electrode.
  • the first electric signal is detected on a first position on a skin of a forehead of the user
  • the second electric signal is detected on a second position on a skin of a back of the head
  • the third electric signal is detected on a third position on a skin of the back of the head.
  • the second position is positioned farther from a ground surface than the third position, when a center axis of the neck of the user is perpendicular to the ground surface.
  • the second position is located on one of mastoid processes and the third position is located on said one or the other of mastoid processes.
  • the plurality of electrodes includes a reference electrode, a first active electrode and a second active electrode.
  • the control unit is configured to obtain an electroencephalogram of a left brain based on a difference between a first electric signal detected from the reference electrode and a second electric signal detected from the first active electrode, obtain an electroencephalogram of a right brain based on a difference between a third electric signal detected from the second active electrode and the first electric signal, and obtain the electrocardiogram based on a difference between the second electric signal and the third electric signal.
  • the first electric signal is detected on a first position on a skin of a forehead of the user
  • the second electric signal is detected on a second position on a skin of a back of the head
  • the third electric signal is detected on a third position on a skin of the back of the head.
  • the second position is located on one of a left mastoid process and a right mastoid process.
  • the third position is located on the other of the left mastoid process and the right mastoid process.
  • the plurality of electrodes includes a first reference electrode, a second reference electrode, a first active electrode and a second active electrode.
  • the control unit is configured to obtain an electroencephalogram of a left brain based on a difference between a first electric signal detected from the first reference electrode and a second electric signal detected from the first active electrode, obtain an electroencephalogram of a right brain based on a difference between a third electric signal detected from the second reference electrode and a forth electric signal detected from the second active electrode, and obtain the electrocardiogram based on a difference between the second electric signal and the forth electric signal.
  • first electric signal and the second electric signal are detected at respective points within a first position on a skin of a back of the head.
  • the third electric signal and the forth electric signal are detected at respective points within a second position on the skin of the back of the head.
  • the first position is located on one of a left mastoid process and a right mastoid process and the second position is located on the other of the left mastoid process and the right mastoid process.
  • the electroencephalogram and electrocardiogram measurement device further includes an ear-hook typed support member to be hung on at least one of two ears.
  • the plurality of electrodes are configured to be supported by the support member.
  • the electroencephalogram and electrocardiogram measurement device further includes an impedance measurement unit configured to measure contact impedances generated between the respective electrodes and a skin of the head with which the electrodes make contact and output a signal for identifying an electrode whose contact impedance exceeds a predetermined value.
  • control unit is further configured to output the electroencephalogram and the electrocardiogram as an electroencephalogram output signal and an electrocardiogram output signal having forms of electric signals.
  • the electroencephalogram and electrocardiogram measurement device further includes a filtering unit configured to filter the electroencephalogram output signal and the electrocardiogram output signal with a first band-pass filter having a first predetermined band pass and a second band-pass filter having a second predetermined band pass, respectively.
  • the electroencephalogram and electrocardiogram measurement device further includes an ADC(analog to digital converter) unit configured to convert the filtered electroencephalogram output signal and electrocardiogram output signal from analog signals into digital signals with a first sampling rate and a second sampling rate, respectively.
  • the first sampling rate and the second sampling rate are determined based on a maximum frequency of the first predetermined band pass and that of the second predetermined band pass, respectively.
  • the electroencephalogram and electrocardiogram measurement device further includes a communication unit configured to transmit the converted electroencephalogram output signal and electrocardiogram output signal to an external device in a first transmission rate and a second transmission rate, respectively.
  • a ratio of the first transmission rate to the second transmission rate is determined based on a ratio of the first sampling rate to the second sampling rate.
  • an electroencephalogram and electrocardiogram measuring method includes detecting electric signals from a head above a neck of a user through a plurality of electrodes, obtaining an electroencephalogram based on the electric signals and obtaining an electrocardiogram based on the electric signals.
  • both an electroencephalogram and an electrocardiogram can be measured by limiting a measurement target region to only a head portion above a user's neck portion.
  • the electrocardiogram can be measured through the use of electrodes required to be basically provided for electroencephalogram measurement.
  • the measurement target body part is limited to the head portion, it is possible to realize a measurement device in a naturally wearable form, such as an earring type, a headset type or the like.
  • Fig. 1 is a schematic diagram illustrating an exemplary configuration of an electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Fig. 2 is a view for explaining the operation of a communication unit of the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Figs. 3A and 3B are views for explaining a one-ear-wearable electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Figs. 4A to 4C are views for explaining a two-ear-wearable electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Figs. 5A and 5B are views for explaining a two-ear-wearable electroencephalogram and electrocardiogram measurement device according to another embodiment of the present disclosure.
  • Fig. 6 is a view for explaining a method of separating an electroencephalogram output signal and an electrocardiogram output signal.
  • Fig. 7 is a flowchart illustrating the respective steps of a method for measuring an electroencephalogram and an electrocardiogram of a user through the use of the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Fig. 8 is a diagram showing the waveforms obtained by an electrocardiogram acquisition unit of the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Fig. 9 is a diagram for explaining an application example of electroencephalogram information obtained by the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Fig. 1 is a schematic diagram illustrating an exemplary configuration of an electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • the electroencephalogram and electrocardiogram measurement device 100 shown in Fig. 1 may include an electrode unit 110, an electroencephalogram acquisition unit 120, an electrocardiogram acquisition unit 130, an impedance measurement unit 140, an amplification unit 150, a filtering unit 160, an analog-to-digital converter (ADC) unit 170, a control unit 180 and a communication unit 190.
  • ADC analog-to-digital converter
  • the electroencephalogram and electrocardiogram measurement device 100 shown in Fig. 1 is nothing more than one embodiment of the present disclosure. Thus, the spirit of the present disclosure shall not be narrowly construed by Fig. 1.
  • An electric signal generated from the body of a user 200 may be detected by a plurality of electrodes 111 included in the electrode unit 110.
  • the electrodes 111 may detect an electric signal in a state in which the electrodes 111 are attached to the skin of the user 200.
  • each of the electrodes 111 may measure an electric signal by measuring an electric potential at a position where the electrode 111 is attached.
  • the electric signals detected by the electrodes 111 of the electrode unit 110 may be transmitted to the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130.
  • the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130 may acquire an electroencephalogram and an electrocardiogram of the user 200 from the transmitted electric signals. More specifically, the electroencephalogram and the electrocardiogram may be obtained from the difference between the electric signals detected by any two of the electrodes 111, i.e., the difference between the electric potentials measured by the two electrodes.
  • Each of the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130 may output the difference in electric potentials measured as described above as an electric signal having a value based on a specific physical quantity (e.g., voltage).
  • electroencephalogram output signal the electric signals outputted by the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130
  • electrocardiogram output signal the electric signals outputted by the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130
  • electrocardiogram output signal the electric signals outputted by the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130
  • electrocardiogram output signal the electric signals outputted by the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130.
  • the impedance measurement unit 140 may measure the contact impedance generated between each electrode 111 and the skin of the user 200 with which each electrode 111 makes contact. If the electrode 111 has the magnitude of the contact impedance larger than a predetermined value, the impedance measurement unit 140 may inform the user 200 of the electrode 111 which has the magnitude of the contact impedance larger than a predetermined value.
  • the impedance measurement unit 140 may know the contact impedance of each electrode 111 by allowing a small amount of electric current to flow toward each electrode 111 before the measurement of an electroencephalogram and an electrocardiogram and then measuring a voltage drop occurring between each electrode 111 and the skin of the user 200. If the impedance measurement unit 140 finds the electrode 111 whose contact impedance exceeds a predetermined value, the impedance measurement unit 140 may output a signal for identifying the corresponding electrode 111 in the form of an electric signal. At this time, the output signal may be converted into a digital signal through the ADC unit 170 which will be described later.
  • an output device such as a display or a speaker connected to the electroencephalogram and electrocardiogram measurement device 100 (or included in the electroencephalogram and electrocardiogram measurement device 100) may output information on the improperly contacted electrode 111 in a user-recognizable form under the control of the control unit 180 which will be described later.
  • the electroencephalogram output signal and the electrocardiogram output signal outputted by the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130 may be amplified through the amplification unit 150. More specifically, the amplification unit 150 may perform amplification for each output signal so that only the amplitude of each output signal is changed while the shape of the waveform is maintained.
  • the voltage amplification ratio, i.e., the gain of the amplification unit 150 may be appropriately adjusted according to the amplitude of the acquired output signal.
  • the amplification unit 150 may be implemented by including an electronic element such as a transistor or an operational amplifier. The details of the implementation of the amplification unit 150 are obvious to those skilled in the art and, therefore, will not be described in more detail.
  • Each output signal passed through the amplification unit 150 may be filtered by the filtering unit 160 so that only a component of a specific frequency band remains.
  • the pass band of the filtering unit 160 may be determined according to the characteristics of each signal. Preferably, a pass band of 1 to 35Hz may be applied to the electroencephalogram output signal, and a pass band of 1 to 100Hz may be applied to the electrocardiogram output signal.
  • the filtering unit 160 may basically perform filtering for both output signals. In some cases, the filtering unit 160 may perform filtering for only one output signal.
  • the filtering unit 160 may basically be implemented so as to include a band-pass filter. In some cases, the filtering unit 160 may be implemented so as to further include a low-pass filter, a high-pass filter, a band-reject filter, or the like.
  • Each output signal passed through the filtering unit 160 may be transmitted to the ADC unit 170.
  • bio signals are acquired as consecutive values for a predetermined time. Therefore, each output signal transmitted through the filtering unit 160 will also be an analog signal.
  • the ADC unit 170 may convert each output signal, which is an analog signal, into a digital signal so as to facilitate data processing, data storage and data transmission through an information processing device. At this time, a sampling rate for conversion into a digital signal may be determined differently for each output signal in consideration of the pass band applied to the filtering unit 160.
  • the sampling rate for each output signal may be set at a value equal to or greater than twice the maximum frequency of the pass band applied to each output signal in the filtering unit 160. For example, when a pass band of 1 to 35Hz is applied to the electroencephalogram output signal and a pass band of 1 to 100Hz is applied to the electrocardiogram output signal, a sampling rate of 128Hz may be applied for the electroencephalogram output signal and a sampling rate of 512Hz may be applied for the electrocardiogram output signal.
  • the detailed implementation method of the ADC unit 170 is also obvious to those skilled in the art and, therefore, will not be described in more detail.
  • the control unit 180 may perform various operations with respect to the digitized output signals that have passed through the ADC unit 170.
  • the control unit 180 may output the waveform of each output signal through an output device (not shown) such as a display or the like connected to the electroencephalogram and electrocardiogram measurement device 100 (or included in the electroencephalogram and electrocardiogram measurement device 100).
  • the control unit 180 may transmit information on each output signal to an external device or a network connected to the electroencephalogram and electrocardiogram measurement device 100 through the communication unit 190.
  • the control unit 180 may be implemented by a computing device including a microprocessor.
  • the communication unit 190 may include a wired or wireless communication module and may transmit the digitized electroencephalogram output signal and the digitized electrocardiogram output signal to the outside of the electroencephalogram and electrocardiogram measurement device 100 at different transmission rates under the control of the control unit 180.
  • the ratio between the transmission rate of the electroencephalogram output signal and the transmission rate of the electrocardiogram output signal may be determined based on the ratio between the sampling rate for the electroencephalogram output signal and the sampling rate for the electrocardiogram output signal, which have been applied to the ADC unit 170.
  • Fig. 2 is a view for explaining the operation of the communication unit of the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • the transmission rate of the electroencephalogram output signal and the transmission rate of the electrocardiogram output signal may also be set such that the latter is four times the former.
  • data on the electrocardiogram output signal (ECG) corresponding to four times the data on the electroencephalogram output signal (EEG) may be transmitted for a predetermined unit time (T).
  • T unit time
  • the electroencephalogram and electrocardiogram measurement device 100 may be implemented in a one-ear-wearable as shown in Figs. 3A and 3B, or in a two-ear-wearable as shown in Figs. 4A to 4C.
  • Figs. 3A and 3B are views for explaining a one-ear-wearable electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • Fig. 3A is a view showing an appearance of a one-ear-wearable electroencephalogram and electrocardiogram measurement device 300 (hereinafter abbreviated as "one-ear-wearable device").
  • the one-ear-wearable device 300 may be implemented such that the user 200 can wear the device 300 on one ear (the left ear in the example of Fig. 3A).
  • the one-ear-wearable device 300 may include a support member 301 for supporting other components thereof.
  • Such a support member 301 may be embodied as an ear-hook type that can be hung on the auricle, for example, as shown in Fig. 3A.
  • the one-ear-wearable device 300 may include an electrode unit 310 including at least three electrodes for detecting electric signals from the skin of the user 200. That is, the electrode unit 310 may correspond to the electrode unit 110 shown in Fig. 1 described above.
  • the three electrodes included in the electrode unit 310 may be referred to as a reference (REF) electrode 311, an active (ACT) electrode 312 and a ground (GND) electrode 313, respectively.
  • the three electrodes 110 may correspond in configuration to the plurality of electrodes 111 included in the electrode unit 110 described above.
  • the reference electrode 311 may detect an electric signal from the skin on the forehead of the user 200.
  • the active electrode 312 and the ground electrode 313 may respectively detect electric signals from the skin of the back of the head of the user 200. More preferably, the active electrode 312 and the ground electrode 313 may be attached to the skin on the bone called a mastoid process, which is present behind the ear, and may detect an electric signal.
  • the ground electrode 313 may make contact with the skin of the user 200 at a position higher than the active electrode 312 (i.e., at a location farther from the ground surface).
  • the reference electrode 311, the active electrode 312 and the ground electrode 313 may all be supported by the support member 301 as shown in Fig. 3A.
  • Fig. 3B is a view showing the detailed configuration of an electrode unit 310, an electroencephalogram acquisition unit 320 and an electrocardiogram acquisition unit 330 included in the one-ear-wearable device 300.
  • the electrode unit 310, the electroencephalogram acquisition unit 320 and the electrocardiogram acquisition unit 330 may correspond to the electrode unit 110, the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130 of the electroencephalogram and electrocardiogram measurement device 100 described with reference to Fig. 1. Therefore, the description overlapping with the description made with reference to Fig. 1 may be omitted below.
  • the one-ear-wearable device 300 may further include components corresponding to the impedance measurement unit 140, the amplification unit 150, the filtering unit 160, the analog-to-digital converter (ADC) unit 170, the control unit 180 and the communication unit 190 of the electroencephalogram and electrocardiogram measurement device 100 described with reference to Fig. 1. These additional components have been described in detail with reference to Fig. 1 and, therefore, will not be further described here.
  • ADC analog-to-digital converter
  • the electroencephalogram acquisition unit 320 may measure a potential difference between the active electrode 312 and the reference electrode 311 among the electrodes of the electrode unit 310 and may output a value of the measured potential difference as an output signal.
  • the electrocardiogram acquisition unit may measure a potential difference between the active electrode 312 and the ground electrode 313 among the electrodes of the electrode unit 310 and may extract and output an electrocardiogram output signal from the value of the measured potential difference.
  • the electrocardiogram acquisition unit 330 may include a signal processing unit 331. That is, the signal processing unit 331 may perform a function for separating only the electrocardiogram output signal from the signal obtained by measuring the potential difference. The operation principle of the signal processing unit 331 will be described later with reference to Fig. 6.
  • the electroencephalogram output signal and the electrocardiogram output signal may also be outputted in the form of continuous waveforms with respect to time.
  • the ground electrode 313 may be connected to a common ground for the electroencephalogram acquisition unit 320 and the electrocardiogram acquisition unit 330.
  • the attaching positions of all the electrodes of the electrode unit 310 may be limited to the head portion above the neck of the user 200. Therefore, the user 200 does not need to attach the electrodes to the position such as the chest, the arm or the like, where it is more difficult to attach electrodes than at the head due to the presence of clothes or the like.
  • All the electrodes of the electrode unit 310 may be supported by one support member 301 as shown in Fig. 3A.
  • the components other than the electrode unit 310 in the one-ear-wearable device 300 may be integrated into a body formed integrally with the support member 301.
  • the one-ear-wearable device 300 may be implemented in the form of an earring-type headset that can be worn, for example, in one ear.
  • the one-ear-wearable device 300 does not occupy the surfaces of the body parts other than the head of the user 200. Therefore, the user 200 may easily wear or take off the one-ear-wearable device 300 and may comfortably and naturally maintain the worn state.
  • Figs. 4A and 4B are views for explaining a two-ear-wearable electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • the two-ear-wearable electroencephalogram and electrocardiogram measurement device 400 (hereinafter abbreviated as "two-ear-wearable device") is more complicated in configuration than the one-ear-wearable device, but may obtain a better measurement result than the one-ear-wearable device.
  • Fig. 4A is a view showing the appearance of the two-ear-wearable device 400.
  • the two-ear-wearable device 400 may be implemented such that the user 200 can wear the device 400 on two ears.
  • the two-ear-wearable device 400 may include support members 401 and 402 for supporting other components included in the device 400.
  • Each of the support members 401 and 402 may be implemented as an ear-hook type that can be hung on the auricle, for example, as shown in Fig. 4A.
  • one support member 401 may be worn on the left ear, and the other support member 402 may be worn on the right ear.
  • the two-ear-wearable device 400 may include an electrode unit 410 including at least three electrodes for detecting electric signals from the skin of the user 200. That is, the electrode unit 410 may correspond in configuration to the electrode unit 110 of FIG. 1 described above.
  • the three electrodes included in the electrode unit 410 may be referred to as a reference (REF) electrode 411, a first active electrode 412 and a second active electrode 413, respectively.
  • the electrode unit 410 may further include a ground (GND) electrode 414 in addition to the basic electrodes mentioned above. These four electrodes may correspond in configuration to the plurality of electrodes 111 included in the above-mentioned electrode unit 110.
  • the reference electrode 411 may detect an electric signal from the skin on the forehead of the user 200.
  • the first active electrode 412, the second active electrode 413 and the ground electrode 414 may detect electric signals from the skin of the back of the head of the user 200.
  • the first active electrode 412 may detect an electric signal from the skin belonging to the left region of the two regions
  • the second active electrode 413 may detect an electric signal from the skin belonging to the right region.
  • the first active electrode 412 and the second active electrode 413 may be attached to the skin above the mastoid processes existing behind the ears in the back of the head and may detect electric signals. That is, the first active electrode 412 may be attached to the left mastoid process, and the second active electrode 413 may be attached to the right mastoid process.
  • the ground electrode 414 may be attached to either of the two mastoid processes. Hereafter, it is assumed that the ground electrode 414 is attached to the left mastoid process on the side of the first active electrode 412.
  • the ground electrode 414 may make contact with the skin of the user 200 at a position higher than the active electrode 412 (i.e., at a location farther from the ground surface).
  • the ground electrode 414 may be attached to a higher position than the second active electrode 413 even when the ground electrode 414 is attached to the right mastoid process.
  • the reference electrode 411, the first active electrode 412 and the ground electrode 414 may be supported by the support member 401 worn on the left ear of the user 200 as described above.
  • the second active electrode 413 may be supported by the support member 402 worn on the right ear.
  • the reference electrode 411 may be supported by the support member 402. If the ground electrode 414 is attached to the mastoid process on the side of the second active electrode 413, the ground electrode 414 may also be supported by the support member 402.
  • Fig. 4B is a view showing the detailed configuration of the electrode unit 410, the electroencephalogram acquisition unit 420 and the electrocardiogram acquisition unit 430 included in the two-ear-wearable device 400.
  • the electrode unit 410, the electroencephalogram acquisition unit 420 and the electrocardiogram acquisition unit 430 may correspond to the electrode unit 110, the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130 of the electroencephalogram and electrocardiogram measurement device 100 described with reference to Fig. 1. Therefore, the description overlapping with Fig. 1 may be omitted below.
  • the electroencephalogram acquisition unit 420 may include a left electroencephalogram acquisition unit 421 and a right electroencephalogram acquisition unit 422 as detailed components, which may acquire an electroencephalogram of the left brain of the user 200 and an electroencephalogram of the right brain of the user 200, respectively.
  • the left electroencephalogram acquisition unit 421 may measure a potential difference between the first active electrode 412 and the reference electrode 411 among the electrodes of the electrode unit 410 and may output a value of the measured potential difference as a left electroencephalogram output signal.
  • the right electroencephalogram acquisition unit 422 may measure a potential difference between the second active electrode 413 and the reference electrode 411 among the electrodes of the electrode unit 410 and may output a value of the measured potential difference as a right electroencephalogram output signal.
  • the electrocardiogram acquisition unit 430 may measure a potential difference between the first active electrode 412 and the second active electrode 413 among the electrodes of the electrode unit 410 and may output a value of the measured potential difference as an electrocardiogram output signal.
  • the ground electrode 414 may be connected to a common ground for the electroencephalogram acquisition unit 420 and the electrocardiogram acquisition unit 430.
  • the two-ear-wearable device 400 may be configured such that the attaching positions of all the electrodes of the electrode unit 410 are limited to the head portion above the neck of the user 200. Therefore, the user 200 does not need to attach the electrodes to the positions other than the head.
  • All the electrodes of the electrode unit 410 may be supported by two support members 401 and 402 that can be hung on the ears as shown in Fig. 4A.
  • the components other than the electrode unit 310 in the two-ear-wearable device 400 may be integrated into the body formed integrally with the support members 401 and 402. Accordingly, the two-ear-wearable device 400 may be realized in the form of an earring type headset. Unlike the one-ear-wearable device 300, the two-ear-wearable device 400 may be in the form of a headset hung on both ears.
  • the two support members 401 and 402 may be connected to each other by a separate connecting member 403 such as a coated wire or the like.
  • the two-ear-wearable device 400 may be implemented as an all-in-one device in which all the components are connected together.
  • the support members 401 and 402 and the connecting member 403 of the two-ear-wearable device 400 are not limited to the example shown in Fig. 4A and may be implemented in any form as long as they can support the sub-components of the two-ear-wearable device 400 including the electrode unit 410.
  • Fig. 4C illustrates an example of one of these various forms.
  • the connecting member 403 is mounted across the forehead of the user 200 to connect the support member 401 on the left ear of the user 200 and the support member 402 (not shown) on the right ear of the user 200.
  • the reference electrode 411 may be mounted on the inner surface of the connecting member 403 which make contact with the forehead of the user 200.
  • the two-ear-wearable device 400 may be implemented so that the electrodes of the electrode unit 410 including the reference electrode 411 do not directly protrude outward. From the viewpoint of overall appearance, it can be seen that the two-ear-wearable device 400 of Fig. 4C may be worn naturally as if the user 200 wears glasses. In addition, due to its natural appearance, the two-ear-wearable device 400 of Fig. 4C may be free from the eyes of other persons as compared with the two-ear-wearable device of Fig. 4A.
  • the two-ear-wearable device 400 does not occupy the surfaces of body parts other than the head of the user 200 and, therefore, may be conveniently used by the user 200.
  • a part of the components of the two-ear-wearable device 400 may be realized by physically separating the same from the main body integrated with the support members 401 and 402 of the two-ear-wearable device 400.
  • some of the components physically separated from the main body may be implemented using the components of a portable electronic device personally held by the user 200. This may holds true in the one-ear-wearable device 300.
  • the reference electrode 311, the active electrode 312 and the ground electrode 313 included in the electrode unit 310 of the one-ear-wearable device 300 are electrodes essentially required to measure the electroencephalogram (the electroencephalogram of the left brain according to Fig. 3A). This means that the one-ear-wearable device 300 does not need to additionally include an electrode for electrocardiogram measurement and can measure the electrocardiogram using only the electrodes for electroencephalogram measurement.
  • the one-ear-wearable device 300 may detect the electrocardiogram of the user 200 using only the electrodes for electroencephalogram measurement attached to the head. Accordingly, the one-ear-wearable device 300 according to an embodiment of the present disclosure may be realized with a simple structure as compared with the prior art. This is advantageous in downsizing and lightening the device. It is also possible to reduce the manufacturing cost.
  • the two-ear-wearable device 400 includes a relatively large number of components as compared with the one-ear-wearable device.
  • the two-ear-wearable device 400 may have an advantage that it can measure both the electroencephalogram of the left brain and the electroencephalogram of the right brain.
  • the reference electrode 411, the first active electrode 412, the second active electrode 413 and the ground electrode 414 included in the electrode unit 410 of the two-ear-wearable device 400 are electrodes essentially provided to measure both the electroencephalogram of the left brain and the electroencephalogram of the right brain. Therefore, the two-ear-wearable device 400 is also capable of measuring the electrocardiogram using only the electrodes for electroencephalogram measurement.
  • the two-ear-wearable device 400 may also have the advantages of the one-ear-wearable device 300.
  • the electrocardiogram output signal outputted through the two-ear-wearable device 400 is superior in signal quality to the electrocardiogram output signal of the one-ear-wearable device 300.
  • a person's electrocardiogram is measured by observing electric signals generated from the left and right portions of the heart.
  • the electric signal generated from the left portion of the heart tends to propagate mainly through the left part of the human body, and the electric signal generated from the right portion of the heart tends to propagate mainly through the right part of the human body.
  • the two-ear-wearable device 400 may extract an electrocardiogram component contained in the electric signal from the brain more effectively than the one-ear-wearable device 300 by measuring all the electric signals from the left and right brains through the first active electrode 412 and the second active electrode 413 and then acquiring the difference between the electric signals.
  • the two-ear-wearable device 400 may directly obtain such an electrocardiogram output signal from the difference between the electric signal of the first active electrode 412 and the electric signal of the second active electrode 413 without going through any separate signal processing process. This is also one of the advantages of the two-ear-wearable device 400.
  • Figs. 5A and 5B are views for explaining a two-ear-wearable electroencephalogram and electrocardiogram measurement according to another embodiment of the present disclosure.
  • the device shown in Figs. 5A and 5B will be referred to as a second two-ear-wearable device 500 as distinguished from the two-ear-wearable device 400 shown in Figs. 4A to 4C.
  • the second two-ear-wearable device 500 is characterized in that it is not necessary to attach electrodes to the forehead.
  • Fig. 5A is a view showing the appearance of the second two-ear-wearable device 500.
  • the second two-ear-wearable device 500 may be implemented such that the user 200 can wear the device 500 on two ears.
  • the second two-ear-wearable device 500 may include support members 501 and 502 for supporting other components included in the second two-ear-wearable device 500.
  • Each of the support members 501 and 502 may be embodied as an ear-hook type that can be hung on the auricle, for example, as shown in Fig. 5A.
  • one support member 501 may be worn on the left ear, and the other support member 502 may be worn on the right ear.
  • the second two-ear-wearable device 500 may include an electrode unit 510 including electrodes for detecting electric signals from the skin of the user 200. That is, the electrode unit 510 may correspond in configuration to the electrode unit 110 shown in Fig. 1. Specifically, the electrode unit 510 may include a first reference (REF) electrode 511, a second reference electrode 512, a first active electrode 513 and a second active electrode 514. In addition, the electrode unit 510 may further include a ground (GND) electrode 515 in addition to the basic electrodes mentioned above. These five electrodes may correspond in configuration to the plurality of electrodes 111 included in the electrode unit 110 described above.
  • Each of the five electrodes may detect electric signals from the skin of the back of the head the user 200.
  • the first reference electrode 511 and the first active electrode 513 may detect an electric signal from the skin belonging to the left region of the two regions
  • the second reference electrode 512 and the second active electrode 514 may detect an electric signal from the skin belonging to the right region.
  • first and second reference electrodes 511 and 512 and the first and second active electrodes 513 and 514 may be attached to the skin above the mastoid processes existing behind the ears in the back of the head and may detect electric signals. That is, the first reference electrode 511 and the first active electrode 513 may be attached to the left mastoid process, and the second reference electrode 512 and the second active electrode 514 may be attached to the right mastoid process.
  • the ground electrode 414 may be attached to either of the two mastoid processes.
  • the first reference electrode 511 may make contact with the skin of the user 200 at a position higher than the first active electrode 513 (i.e., at a location farther from the ground surface).
  • the second reference electrode 512 may also make contact with the skin of the user 200 at a position higher than the first active electrode 514.
  • the ground electrode 515 may be attached to either of the two mastoid processes.
  • the ground electrode 515 is attached to the left mastoid process on the side of the first reference electrode 511 and the first active electrode 513.
  • the ground electrode 515 may be attached so that the height thereof is lower than that of the first reference electrode 511 and higher than that of the first active electrode 513.
  • the ground electrode 515 may be attached so that the height thereof is lower than that of the second reference electrode 512 and higher than that of the second active electrode 514.
  • the first reference electrode 511, the first active electrode 513 and the ground electrode 515 may be supported by a support member 501 worn on the left ear of the user 200.
  • the second reference electrode 512 and the second active electrode 515 may be supported by a support member 502 worn on the right ear.
  • the two support members 501 and 502 may be connected by a connecting member 503 so that the second two-ear-wearable device 500 can be integrally implemented.
  • the connecting member 503 is located on the back of the head rather than on the forehead of the user 200 as shown in Fig. 5A, the components of the second two-ear-wearable device 500 do not appear on the front of the head. Accordingly, the user 200 may comfortably and naturally wear the second two-ear-wearable device 500 and may be relatively free from the eyes of other persons.
  • Fig. 5B is a view showing the detailed configuration of the electrode unit 510, the electroencephalogram acquisition unit 520 and the electrocardiogram acquisition unit 530 included in the second two-ear-wearable device 500.
  • the electrode unit 510, the electroencephalogram acquisition unit 520 and the electrocardiogram acquisition unit 530 may correspond to the electrode unit 110, the electroencephalogram acquisition unit 120 and the electrocardiogram acquisition unit 130 of the electroencephalogram and electrocardiogram measurement device 100 described with reference to Fig. 1. Therefore, the description overlapping with Fig. 1 may be omitted below.
  • the electroencephalogram acquisition unit 520 may include a left electroencephalogram acquisition unit 521 and a right electroencephalogram acquisition unit 522 as detailed components, which may acquire an electroencephalogram of the left brain of the user 200 and an electroencephalogram of the right brain of the user 200, respectively.
  • the left electroencephalogram acquisition unit 521 may measure a potential difference between the first active electrode 513 and the first reference electrode 511 among the electrodes of the electrode unit 510 and may extract and output a left electroencephalogram output signal from a value of the measured potential difference.
  • the right electroencephalogram acquisition unit 522 may measure a potential difference between the second active electrode 514 and the second reference electrode 512 among the electrodes of the electrode unit 510 and may extract and output a right electroencephalogram output signal from a value of the measured potential difference.
  • the electrocardiogram acquisition unit 530 may measure a potential difference between the first active electrode 513 and the second active electrode 514 among the electrodes of the electrode unit 510 and may output a value of the measured potential difference as an electrocardiogram output signal.
  • the ground electrode 515 may be connected to a common ground for the electroencephalogram acquisition unit 520 and the electrocardiogram acquisition unit 530.
  • the left electroencephalogram acquisition unit 521 may include a signal processing unit 523 for extracting a left electroencephalogram output signal from the potential difference between the first active electrode 513 and the first reference electrode 511.
  • the right electroencephalogram acquisition unit 522 may also include a signal processing unit 524 for extracting a right electroencephalogram output signal from the potential difference between the second active electrode 514 and the second reference electrode 512.
  • a simple method that can be considered for the operation of the signal processing units 523 and 524 is to use the electrocardiogram output signal outputted by the electrocardiogram acquisition unit 530.
  • the signal processing unit 523 may obtain a left electroencephalogram output signal by obtaining the difference between the waveform obtained by measuring the potential difference between the first active electrode 513 and the first reference electrode 511 and the signal obtained by scaling the electrocardiogram output signal.
  • the signal processing unit 524 may obtain a left electroencephalogram output signal by obtaining the difference between the waveform obtained by measuring the potential difference between the second active electrode 514 and the second reference electrode 512 and the signal obtained by scaling the electrocardiogram output signal. Details of such a series of processes are obvious to those skilled in the art and, therefore, will not be described in detail.
  • Fig. 6 is a view for explaining a method of separating an electroencephalogram output signal and an electrocardiogram output signal.
  • the method described with reference to Fig. 6 is an exemplary method for separating a specific component from a mixed signal of an electroencephalogram component and an electrocardiographic component. This method may be applied to the operation of the signal processing unit 331 of the one-ear-wearable device 300 or the operation of the signal processing unit 523 or 524 of the second two-ear-wearable device 500.
  • the electrocardiogram component When separating the electroencephalogram component and the electrocardiogram component, it may be possible to utilize the fact that the electrocardiogram component is mainly observed in a specific frequency band (approximately 10 to 30Hz is, the electrocardiogram component may be obtained by extracting a signal of a specific frequency band from the mixed signal in which the electroencephalogram component and the electrocardiogram component are mixed, and the electroencephalogram component may be obtained by removing the electrocardiogram component from the mixed signal. This makes it possible to separate the mixed signal into the electroencephalogram component and the electrocardiogram component.
  • a specific frequency band approximately 10 to 30Hz is, the electrocardiogram component may be obtained by extracting a signal of a specific frequency band from the mixed signal in which the electroencephalogram component and the electrocardiogram component are mixed, and the electroencephalogram component may be obtained by removing the electrocardiogram component from the mixed signal.
  • Fig. 6(a) shows an exemplary waveform in which an electroencephalogram component and an electrocardiogram component are mixed.
  • a waveform of an electrocardiogram component which is a waveform of Fig. 6(b) may be obtained by applying a filtering technique such as a wavelet transform or the like to the waveform of Fig. 6(a) and extracting the signal of the specific frequency band.
  • a filtering technique such as a wavelet transform or the like
  • the peak of the waveform of the electrocardiogram component may be made more distinct.
  • the waveform of Fig. 6(d) is a waveform obtained by extracting only the peak value from the waveform of Fig. 6(c). Referring to the waveform of Fig. 6(c), it can be seen that the signal value is almost zero in most of the sections, but the sections having several peaks appears at intervals of about 0.7 to 0.8 seconds.
  • the waveform of Fig. 6(d) may be obtained by extracting only the portion including the largest peak value (R-peak) from the respective sections.
  • an adaptive peak finding technique such as adaptive thresholding or the like may be used for accurate R-peak extraction.
  • the waveform of Fig. 6(d) is a waveform having a squared dimension as compared with the dimension of Fig. 6(b) (for example, when the dimension of Fig. 6(b) is "V", the dimension of Fig. 6(c) or 6(d) is "V 2 ").
  • the waveform may be processed to have the dimension of Fig. 6(b) by taking the square root of the waveform of Fig. 6(d) and applying a sign with reference to the waveform of Fig. 6(b).
  • the signal processing units 331, 523 and 524 may extract and output the electrocardiogram output signal, the left electroencephalogram output signal and the right electroencephalogram output signal, respectively.
  • the method of Fig. 6 is nothing more than an example of one of the methods applicable to the signal processing units 331, 523 and 524. It goes without saying that another method may be applied to the operations of the signal processing units 331, 523 and 524 according to an embodiment of the present disclosure.
  • Fig. 7 is a view illustrating the respective steps of a method for measuring an electroencephalogram and an electrocardiogram of a user using the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • the description of the parts overlapping with those of Figs. 1 to 4 may be omitted. It should be noted that the following steps are not necessarily performed in order, and the order may be changed as necessary.
  • the user 200 may attach each of the plurality of electrodes 111 included in the electrode unit 110 to the surface of the skin existing on the head of the user 200 (S101).
  • the configuration of the electrodes 111 and the attachment positions of the respective electrodes 111 may vary depending on whether the electroencephalogram and electrocardiogram measurement device 100 is the one-ear-wearable device 300 or the two-ear-wearable device 400.
  • each of the electrodes 111 is correctly attached to the skin of the user 200 (S102).
  • a confirming step may be performed by the impedance measurement unit 140.
  • the next step of measuring electric signals from the user 200 may be started after confirming that all the electrodes 111 have been correctly attached.
  • electroencephalogram acquisition unit 120 may acquire an electroencephalogram of the user 200 (S104) and the electrocardiogram acquisition unit 130 may acquire an electrocardiogram of the user 200 (S105).
  • signal processing for the electroencephalogram output signal and the electrocardiogram output signal as the results of electroencephalogram and electrocardiogram acquisition may be performed (S106).
  • Such signal processing may include the amplification by the amplification unit 150, the filtering by the filtering unit 160, and the conversion to a digital signal by the ADC unit 170. Details of each operation have been described above with reference to Fig. 1 and, therefore, will not be described here.
  • the electroencephalogram output signal and the electrocardiogram output signal may be outputted through the output device, or may be transmitted to an external device or a network connected to the electroencephalogram and electrocardiogram measurement device 100 (S170).
  • Fig. 8 is a view showing the waveforms obtained by the electrocardiogram acquisition unit of the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • the upper waveform is a waveform obtained by the electrocardiogram acquisition unit 330 of the one-ear-wearable device 300 and is a waveform from which the electroencephalogram component is not removed by the signal processing unit 331.
  • the lower waveform is a waveform of the electrocardiogram output signal obtained by the electrocardiogram acquisition unit 430 of the two-ear-wearable device 400.
  • a mixed signal of an electroencephalogram component and an electrocardiogram component is obtained through the electrode unit 310.
  • a pure electrocardiogram waveform can be obtained by separating the electroencephalogram component from the mixed signal through the use of the signal processing unit 331.
  • the two-ear-wearable device 400 can obtain a pure electrocardiogram waveform immediately from the electrode unit 410.
  • the spacing between adjacent peaks in the electrocardiogram waveform indicates the spacing between the heartbeats. By observing the distribution of such peaks, it is possible to know the speed and regularity of the heartbeats. Such information on the heartbeats may be used to diagnose the occurrence of heart-related diseases such as arrhythmia or the like.
  • Fig. 9 is a diagram for explaining an application example of electroencephalogram information obtained by the electroencephalogram and electrocardiogram measurement device according to an embodiment of the present disclosure.
  • the waveform shown in Fig. 9 is a frequency spectrum corresponding to the electroencephalogram waveform obtained by the electroencephalogram and electrocardiogram measurement device 100 according to an embodiment of the present disclosure.
  • the electroencephalogram may be used to test the cognitive ability of a subject. For example, when a visual stimulus having a certain frequency is applied to a subject, the corresponding frequency component is detected in the electroencephalogram waveform if the cognitive ability of the subject is normal. The generation of such a frequency component is attributable to the visual stimulation. Conversely, if the frequency component is not detected from the electroencephalogram waveform, it can be diagnosed that there is a problem in the cognitive ability of the subject.
  • an electroencephalogram waveform of the user 200 was acquired through the electroencephalogram and electrocardiogram measurement device 100. Then, the frequency spectrum as shown in Fig. 9 was obtained through the frequency analysis of the obtained waveform.
  • the combinations of respective sequences of a flow diagram attached herein may be carried out by computer program instructions. Since the computer program instructions may be executed by processors of a general purpose computer, a special purpose computer, or other programmable data processing apparatus, the instructions, executed by the processor of the computer or other programmable data processing apparatus, create means for performing functions described in the respective sequences of the sequence diagram.
  • the computer program instructions in order to implement functions in a specific manner, may be stored in a memory useable or readable by the computer or a computer for other programmable data processing apparatus, and the instructions stored in the memory useable or readable by a computer may produce manufacturing items including an instruction means for performing functions described in the respective sequences of the sequence diagram.
  • the computer program instructions may be loaded in a computer or other programmable data processing apparatus, and therefore, the instructions, which are a series of sequences executed in a computer or other programmable data processing apparatus to create processes executed by a computer to operate a computer or other programmable data processing apparatus, may provide operations for executing functions described in the respective sequences of the flow diagram.
  • the respective sequences may refer to two or more modules, segments, or codes including at least one executable instruction for executing a specific logical function(s).
  • the functions described in the sequences may be run out of order. For example, two consecutive sequences may be substantially executed simultaneously or often in reverse order according to the corresponding functions.

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Abstract

La présente invention concerne un dispositif de mesure d'électroencéphalogramme et d'électrocardiogramme. Ce dispositif comprend une pluralité d'électrodes conçues pour détecter des signaux électriques en provenance de la tête au-dessus du cou d'un utilisateur, ainsi qu'une unité de commande conçue pour obtenir un électroencéphalogramme et un électrocardiogramme de l'utilisateur sur la base des signaux électriques détectés.
PCT/KR2018/007245 2017-06-26 2018-06-26 Dispositif et procédé de mesure d'électroencéphalogramme et d'électrocardiogramme WO2019004710A1 (fr)

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CN111528837A (zh) * 2020-05-11 2020-08-14 清华大学 可穿戴脑电信号检测装置及其制造方法
WO2021120330A1 (fr) * 2019-12-19 2021-06-24 歌尔股份有限公司 Écouteur

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KR102243824B1 (ko) * 2019-02-27 2021-04-23 주식회사 에이티센스 이종의 생체 신호의 동시 측정 장치 및 그 측정 방법
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KR102495649B1 (ko) 2021-03-18 2023-02-06 재단법인대구경북과학기술원 심리생리학적 지표 측정을 통한 공격성 특질 분석 및 모니터링 시스템
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KR102603579B1 (ko) * 2023-04-12 2023-11-20 주식회사 피치라이프사이언스 뇌파측정이 가능한 비침습 뇌신경 자극 장치

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