WO2018221220A1 - Automatic analysis device - Google Patents

Automatic analysis device Download PDF

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Publication number
WO2018221220A1
WO2018221220A1 PCT/JP2018/018905 JP2018018905W WO2018221220A1 WO 2018221220 A1 WO2018221220 A1 WO 2018221220A1 JP 2018018905 W JP2018018905 W JP 2018018905W WO 2018221220 A1 WO2018221220 A1 WO 2018221220A1
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WO
WIPO (PCT)
Prior art keywords
rack
sample
sample rack
loading
tray
Prior art date
Application number
PCT/JP2018/018905
Other languages
French (fr)
Japanese (ja)
Inventor
元 末成
達也 福垣
三島　弘之
晃啓 安居
武 瀬戸丸
Original Assignee
株式会社日立ハイテクノロジーズ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 株式会社日立ハイテクノロジーズ filed Critical 株式会社日立ハイテクノロジーズ
Priority to JP2019522100A priority Critical patent/JP6941672B2/en
Publication of WO2018221220A1 publication Critical patent/WO2018221220A1/en

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system

Definitions

  • the present invention relates to an automatic analyzer that transports a sample rack that holds a sample for analyzing a component in a biological sample such as blood and urine, and collects the sample in an analysis unit.
  • a plurality of analysis unit units are arranged along a sample rack transport unit to which a sample rack loaded with a plurality of containers containing samples is transported. ing.
  • a rack supply unit is disposed on the left side of the transfer line, and a rack collection unit is disposed on the right side.
  • a sample rack buffer unit is installed at an intermediate position of the sample rack transport module, and the sample rack in the middle of sample dispensing is preferentially analyzed.
  • the sample rack in which the sample to be performed is stored can be replaced.
  • the sample rack buffer mechanism located in the middle of the sample rack transport line is a loop-shaped rack standby disk, and stores a plurality of sample racks.
  • the sample racks can be sent to the analysis unit in any order, and the sample racks can be stored in any order.
  • a sample rack buffer unit is provided in the sample rack collection unit.
  • the sample rack is temporarily moved to the respective sample rack buffer units of the rack supply unit and the rack collection unit, so that the sample rack tray can be taken out and an additional sample can be loaded.
  • the rack transport unit becomes large.
  • An object of the present invention is to provide a sample rack that can be taken out directly from the sample rack tray without providing a separate buffer mechanism, and even if the sample rack remains in the sample rack tray, This is to realize an automatic analyzer that can be carried out and loaded with an additional sample rack.
  • the present invention is configured as follows.
  • an analysis unit for analyzing a sample a sample rack loading / unloading mechanism having a loading / unloading line for loading a sample rack holding a sample container into the analysis unit and unloading the sample container from the analysis unit,
  • a sample rack tray for installing the sample rack is detachably installed, a sample container loading mechanism for loading the sample rack into the loading / unloading line of the sample rack loading / unloading mechanism, and the sample rack tray are detachably installed.
  • a sample container storage mechanism that collects and stores the sample rack from the load / unload line, and an operation control unit that controls operations of the analyzer, the sample rack load / unload mechanism, the sample container input mechanism, and the sample container storage mechanism.
  • the sample rack can be taken out directly from the sample rack tray, and even if the sample rack remains in the sample rack tray, the sample rack tray is taken out and added. Thus, it is possible to realize an automatic analyzer that can input the sample rack.
  • FIG. 1 is an overall configuration diagram of an automatic analyzer to which an embodiment of the present invention is applied. It is a schematic perspective view of the sample rack tray installed in the sample container loading mechanism in one embodiment of the present invention.
  • FIG. 6 is an explanatory diagram of a sample rack loading operation by a sample rack loader mechanism in an embodiment of the present invention. It is a carrying-out simplified explanatory drawing of the rack unloader mechanism in one Example of this invention. It is a simplified explanatory view of the rack tray carry-out operation of the rack loader mechanism in one embodiment of the present invention.
  • FIG. 6 is a simplified explanatory view of a loading operation when a rack is loaded from a rack emergency lane (STAT lane) in one embodiment of the present invention.
  • STAT lane rack emergency lane
  • 6 is a flowchart showing additional sample rack loading / sample rack tray removal in an embodiment of the present invention.
  • 6 is a flowchart showing the operation logic in the sample rack loader mechanism / sample rack unloader mechanism when an instruction to complete loading of an additional sample rack is given in an embodiment of the present invention.
  • 6 is a flowchart showing the operation logic in the rack loader mechanism / rack unloader mechanism when an emergency sample rack is instructed to be inserted from the STAT line in one embodiment of the present invention.
  • FIG. 1 is an overall configuration diagram of an automatic analyzer to which one embodiment of the present invention is applied.
  • the automatic analyzer includes a sample container loading mechanism (sample rack loader mechanism) 1, a sample container storage mechanism (sample rack unloader mechanism) 2, and an emergency sample rack loading mechanism of a rack feeder mechanism 3 on the front surface of the apparatus. ing.
  • the sample rack is loaded into and removed from the rack standby disk 4 via the sample container loading mechanism (sample rack loader mechanism) 1, the sample container storage mechanism (sample rack unloader mechanism) 2, and the rack feeder mechanism 3.
  • sample container loading mechanism sample rack loader mechanism
  • sample container storage mechanism sample rack unloader mechanism
  • rack feeder mechanism the rack feeder mechanism 3.
  • An analyzer can be connected to the left and right sides of the specimen container loading mechanism 1, the specimen container storage mechanism 2, and the rack feeder mechanism 3.
  • a biochemical analyzer 5 is arranged on the right side, and an immunity is placed on the left side.
  • An analyzer 6 is arranged. Not only this arrangement, but also a configuration in which the biochemical analyzer is arranged on the left side of the specimen container loading mechanism 1, the specimen container storage mechanism 2, and the rack feeder mechanism 3, and the immunological analyzer is arranged on the right side, and analysis on both the left and right sides
  • Both devices may be biochemical analyzers or both immunoassays.
  • the sample container loading mechanism 1 and the sample container storage mechanism 2 can supply and store the sample racks independently through the rack standby disk 4 to the analyzers 5 and 6 on both sides.
  • the biochemical analyzer 5 includes a sampling line 7, a reagent cool box 10, and a reaction unit 12 as main components.
  • the immune analyzer 6 includes a sampling line 13, a sample sampling mechanism 14, and a reagent cold storage 17 as main components.
  • the biochemical analyzer 5 and the immune analyzer 6 include other components.
  • the sample container loading mechanism 1 includes a sample rack loader mechanism arm 23 and a rack return mechanism action point arm (rack return arm) 43.
  • the sample container storage mechanism 2 includes a sample rack unloader mechanism arm 32.
  • a rack return mechanism force point arm 41 for driving the rack return mechanism action point arm 43 and the sample rack unloader mechanism arm 32 is disposed in the vicinity of the sample container loading mechanism 1 and the sample container storage mechanism 2 with the rack feeder mechanism 3 interposed therebetween. Has been.
  • a microcomputer 15 which is an operation control unit for controlling the operation of the entire automatic analyzer and a display unit 16 are provided. That is, the microcomputer 15 controls the operations of the analysis unit (the biochemical analysis device 5 and the immunological analysis device 6), the sample rack loading / unloading mechanism (rack feeder mechanism 3), the sample container loading mechanism 1, and the sample container storage mechanism 2. To do.
  • FIG. 2 is a schematic perspective view of the sample rack tray 18 installed in the sample container loading mechanism 1 or the sample container storage mechanism 2.
  • the sample rack tray 18 is constructed such that a plurality of sample racks 19 are installed on the sample rack tray 18 and can be carried.
  • the rack mounting portion of the sample rack tray 18 is formed with a protrusion that can be inserted into the sample rack overturn prevention groove 20 formed in the sample rack 19, and when the sample rack 19 is transported from the sample rack tray 18,
  • the structure is such that the sample rack 19 does not fall over when the sample rack tray 18 is carried.
  • the left and right handle portions of the sample rack tray 18 operate upward, and the sample rack 19 is prevented from falling out of the sample rack tray 18 when the sample rack tray 18 is carried.
  • FIG. 3 is an explanatory view of the loading operation of the sample rack 19 of the sample rack loader mechanism 1 which is a sample container loading mechanism.
  • the sample rack loader mechanism 1 includes an input sample rack tray installation base 21 to which a sample rack tray 18 can be attached and detached, and an input sample rack tray 22 on which a sample rack 19 holding a sample container 60 is installed.
  • the sample rack 19 can be installed by the sample rack tray 22.
  • a rack tray presence / absence sensor 300 for detecting whether or not the sample rack tray 22 is installed is attached to the rack tray installation base 21 so that it can be confirmed whether or not the sample rack 19 can be loaded. It has become.
  • sample rack 19 When the input sample rack 19 is installed on the sample rack tray 22, the sample rack 19 is sent out in the rack feed operation direction 24 of the sample rack loader mechanism arm 23 by the sample rack loader mechanism arm 23 moved by the loader arm moving mechanism 51. .
  • a sample rack presence / absence detection sensor (rack arrival sensor to feeder line) 25 is disposed on the opposite side of the position where the sample rack tray 22 is set with the sample rack feeder mechanism loading / unloading line 29 in between.
  • one sample rack 19 that has reached the rack arrival position 26 of the sample rack feeder mechanism loading / unloading line 29 is carried by the rack feeder mechanism 3, and a rack barcode and a sample barcode are scanned by the sample / sample rack barcode reader 27. Is read, moved to the sample rack feeder mechanism loading trajectory (vertical direction) 28, and loaded into the rack standby disk 4 from the sample rack feeder mechanism loading / unloading line 29.
  • the sample / sample rack barcode reader 27 is provided with a sensor for detecting the height of the test tube containing the sample, and can be used as a parameter for sample dispensing operation by grasping the test tube height information.
  • the test tube information (test tube diameter, test tube height, test tube cap shape, test tube cap color) may be read by the sample / sample rack barcode reader 27 itself.
  • FIG. 4 is a simplified explanatory diagram of the reset operation of the rack unloader mechanism 2 in the rack return mechanism that returns the sample rack 19 from the rack standby disk 4 to the sample container storage mechanism 2.
  • the rack unloader mechanism (sample container storage mechanism) 2 includes a storage sample rack tray installation base 34 to which the sample rack tray 18 can be attached and detached.
  • the unloader arm moving mechanism 50 causes the sample rack unloader mechanism arm 32 to move from the state shown in FIG. 4 to the sample rack unloader mechanism arm unloading operation driving direction (from left to right in FIG. 4). Yes, the sample rack 19 is moved in the direction 33) in which the sample rack 19 is moved from the carry-in conveyance line 29 to the sample rack tray 35), and the sample rack 19 is moved.
  • sample rack 19 is collected and stored in the storage sample rack tray 35 installed on the storage sample rack tray installation base 34.
  • a rack tray presence / absence sensor 301 for detecting whether or not the stored sample rack tray 35 is installed on the stored sample rack tray installation base 34 is attached to the stored sample rack tray installation base 34.
  • the stored sample rack 36 in the stored sample rack tray 35 is pushed by the next sample rack stored in the stored sample rack tray 35, and is erected to the back where there is space in the stored sample rack tray 35, so that the stored sample rack is full. It can be stored until the sensor 37 is detected.
  • the stored sample rack 36 in the stored sample rack tray 35 of the detection container storage mechanism 2 can be taken out without providing a separate rack buffer unit.
  • the sample rack 19 is positioned at the input waiting sample rack standby position 38 that is the position closest to the sample rack feeder mechanism carry-in / out line 2, and the sample rack 19 is in the sample rack feeder mechanism carry-in / out line 29. It is comprised so that it may not be conveyed by.
  • FIG. 5 is a simplified explanatory view of the rack tray unloading operation of the rack loader mechanism 1.
  • the sample rack 19 and the input sample rack tray 22 Since the sample rack has come to the boundary with the feeder mechanism unit 3, it is necessary to push the sample rack 19 back to the input sample rack tray 22.
  • the sample rack loader mechanism arm 23 When the rack loader mechanism arm 23 continues to push the sample rack 19 toward the loading / unloading line 29, the sample rack 19 cannot be returned to the specified position on the rack tray 22. For this reason, it is first necessary to return the rack loader mechanism arm 23 to the initial position.
  • the sample rack loader mechanism arm 23 is moved in the reset operation direction (direction opposite to the rack delivery operation direction 24) 39 and moved to the sample rack loader mechanism arm standby position (home position) 40.
  • the rack loader mechanism arm 23 does not return to the sample rack loader mechanism arm standby position (home position) 40 and moves in the rack sample rack loader mechanism arm reset operation direction 39 by one sample rack. Even if the rack return operation itself can be performed, it is desirable to return to the sample rack loader mechanism arm standby position (home position) 40 in consideration of taking out and reinserting the sample rack tray 22.
  • the rack return mechanism force point arm 41 is connected to the rack return mechanism action point arm 43 with the rack return mechanism fulcrum 42 as the center, and the rack return mechanism force point arm 41 is moved by the unloader arm moving mechanism 50.
  • the rack unloader mechanism arm 32 moves and is pushed in a direction (operation direction opposite to the drive direction 33) 44 that receives a force from the rack unloader mechanism arm 32.
  • the rack return mechanism operating point arm 43 operates so as to move in the return operation direction 45 (the direction in which the sample rack 19 on the sample rack tray 22 moves away from the loading / unloading line 29 of the sample rack loading / unloading mechanism 3) 45.
  • the sample rack 19 can be returned to the specified input waiting sample rack standby position 46 on the sample rack tray 22. Thereafter, the rack return mechanism 43 returns to the home position (position shown in FIG. 6).
  • the rack return mechanism may be independently operated separately by increasing the number of drive shafts.
  • the sample rack tray 22 is unloaded, and after the sample rack 19 is additionally loaded into the sample rack tray 22, the sample rack tray 22 is loaded on the loaded sample rack tray installation base 21, and then one conveyance line of the rack feeder mechanism 3.
  • the sample rack 19 is sent to the (loading / unloading line 29), and then the rack returning operation is performed to the position as shown in FIG.
  • the sample rack position is reset to a specified position even if the sample rack 19 already installed is accidentally pushed out to one transport line side. Can do.
  • a rack presence / absence detection sensor 25 is installed in one transport line, the sample rack tray 22 is taken out, the unloaded sample rack 19 is added and reinstalled, and then the rack return operation is performed.
  • the microcomputer 15 calculates the feed amount of the sample rack loader mechanism arm 23 at the sample rack detection timing by the rack presence / absence detection sensor 25, the number of sample racks 19 loaded can be calculated and grasped from the calculated feed amount. .
  • the sample rack 19 can be additionally supplied to the sample rack tray 22 without providing a separate buffer unit.
  • FIG. 6 is a simplified explanatory diagram of the loading operation when the rack is loaded from the emergency rack lane (STAT lane).
  • the emergency sample Upon confirming the availability of the rack standby disk 4 and the operating status of the loader mechanism / unloader mechanism and receiving a signal that can be carried in, the emergency sample is loaded into the emergency sample rack loading unit drive direction 48, and the sample / sample rack barcode The reader 27 reads the rack barcode / sample barcode and puts the emergency sample rack into the rack standby disk 4.
  • the microcomputer (operation control unit) 15 controls the sample dispensing / reagent dispensing / washing water pump via the interface.
  • the microcomputer 15 also controls the sample rack loading / unloading unit, and controls the loading / unloading of the sample rack 19 with respect to the rack standby disk 4 so that the unprocessed sample rack 19 is not congested. To control.
  • the microcomputer 15 controls so that an emergency sample can be measured rapidly.
  • Analytical parameters relating to items that can be analyzed by the automatic analyzer are previously input to the microcomputer 15 via the display unit 16 that is an information input device such as a touch panel and stored in a storage medium.
  • the operator uses the operation function screen of the display unit 16 connected to the microcomputer 15 to select the inspection item requested for each sample.
  • FIG. 7 is a flowchart showing sample rack additional input / sample rack tray removal.
  • step S1 of FIG. 7 when the operator gives an instruction to add a sample rack / take out a sample rack tray, the microcomputer 15 as the operation control unit performs a reset operation of the rack loader / rack unloader mechanism.
  • An instruction to add a sample rack is input from the display unit 16 (such as a touch panel). You may make it instruct
  • step S2 it is confirmed whether or not the rack carrier position for carrying the rack of the rack feeder mechanism 3 is in the home position. If the rack carrier position is other than the home position, the rack carrying in / out operation of the rack feeder mechanism 3 in step S3 is continued. When processing for one rack, which was in the middle of processing, is completed, it moves to the home position.
  • the home position indicates the position shown in FIG. 6 except for the emergency sample rack arranged at the emergency sample rack loading position.
  • step S2 when the rack carrier position for carrying the rack of the rack feeder mechanism 3 is in the home position, the process proceeds to step S4.
  • step S4 the arm position of the unloader mechanism arm 32 in the sample rack unloader mechanism 2 is confirmed. If the arm position is not at the home position, the unloader mechanism arm 32 is moved to the home position in step S5 and processed from the sample rack unloader mechanism 2. The ready sample rack tray 35 is made ready for removal.
  • step S4 when the arm position of the unloader mechanism arm 32 is at the home position, the process proceeds to step S6.
  • step S6 the sample rack loader mechanism arm 23 of the sample rack loader mechanism 1 is moved to the home position 40 so that the rack return operation can be performed.
  • step S7 the rack return operation is performed.
  • step S8 the display unit 16 (touch panel monitor or LED) connected to the microcomputer 15 displays that the additional loading of the sample rack 19 is possible, and enters an instruction waiting state in step S9. And transition.
  • FIG. 8 is a flowchart showing the operation logic in the sample rack loader mechanism 1 and the sample rack unloader mechanism 2 when an instruction to complete the addition of the additional sample rack is given.
  • step S101 After the operator completes the loading of the sample rack 19 or the sample rack tray 18, in step S101, the operator gives a sample rack loading completion instruction / sample rack tray completion instruction with the touch panel or push button of the display unit 16.
  • the microcomputer 15 as the operation control unit confirms the ON / OFF of the rack tray presence / absence sensors 300 and 301 in step S102. If OFF, the process proceeds to step S103, and the display unit 16 displays a tray out alarm.
  • step S102 If there is a sample rack tray in step S102, the process proceeds to step S104, and the sample rack loader mechanism arm 23 is moved to the rack feeder line (sample rack feeder mechanism loading / unloading line) 29 side.
  • step S105 the sample rack presence / absence detection sensor 25 installed in the vicinity of the rack feeder line 29 detects whether the sample rack 19 has arrived. If the sample rack presence / absence detection sensor 25 remains OFF even after the sample rack feeding by the sample rack loader mechanism arm 23 is completed, the process proceeds to step S106, and a no rack alarm is displayed on the display unit 16.
  • step S105 If the rack arrival sensor 25 is turned on in step S105, the process proceeds to step S107, and the movement of the sample rack loader mechanism arm 23 is stopped. By checking the stop position of the sample rack loader mechanism arm 23 by the arm feed amount, it is possible to grasp how many sample racks 19 are held in the sample rack loader mechanism 1.
  • step S108 the rack return operation in step S108 is executed. And it changes to the state which waits for the next instruction
  • the rack returning operation itself in step S108 may be omitted, but the next operation is not the loading of the sample rack 19 from the sample rack loader mechanism 1, but the emergency sample rack.
  • the rack unloader mechanism 2 When loading or unloading the sample rack to / from the rack unloader mechanism 2, there is a possibility that the operating area of the rack feeder mechanism 3 may be disturbed, so it is desirable to return the sample rack 19 to the specified position by the rack return mechanism.
  • FIG. 9 is a flowchart showing the operation logic in the rack loader mechanism 1 and the rack unloader mechanism 2 when an emergency sample rack is instructed from the STAT line (emergency sample rack input position) 47.
  • STAT line emergency sample rack input position
  • the rack presence / absence sensor 100 is turned on, and an instruction to load the emergency sample rack is issued in step S201.
  • the mechanism in operation continues to complete the operation for one rack, and then the emergency sample loading operation is interrupted. That is, when the rack presence / absence detection sensor 100 detects that an emergency sample rack is installed in the emergency sample lane 47, the analyzers 5 and 6, the sample rack loading / unloading mechanism 3, the sample container loading mechanism 1, and the sample container storage mechanism 2 are used. In this case, after completing the processing of the sample held in the one sample rack 19 during the operation, the emergency sample carrying-in operation is interrupted.
  • step S202 it is confirmed whether or not the position of the carrier (member for moving the sample rack) of the rack feeder mechanism 3 is at the home position. If the position is other than the home position, the process proceeds to step S203 and the operation for one rack is performed. The carrier of the rack feeder mechanism 3 is moved to the home position.
  • step S204 the position of the unloader mechanism arm 32 is confirmed. If it is not in the home position (the position shown in FIG. 6 where the sample rack 19 and the unloader mechanism arm 32 are not positioned on the loading / unloading line 29), the process proceeds to step S205.
  • the unloader mechanism arm 32 is moved to a home position that is not located on the loading / unloading line 29 so as not to disturb the loading operation of the emergency sample rack.
  • step S204 if the unloader mechanism arm 32 is located at the home position, the process proceeds to step S206.
  • step S206 the rack loader mechanism arm 23 of the sample rack loader mechanism 1 is moved to the home position so that the rack return operation can be performed, and the rack return operation in step S207 is performed.
  • the sample rack 19 is returned from the loading / unloading line 29 to the sample rack tray 22 by the rack return mechanism operating point arm 43, and is opposite to the direction in which the rack return mechanism operating point arm 43 returns the sample rack 19 to the sample rack tray 22. , Passes through the loading / unloading line 29, and moves to a position that does not hinder the loading operation of the emergency sample rack (home position shown in FIG. 6).
  • step S208 the carrier of the feeder mechanism 3 is moved to the STAT carry-in position 47 in step S208. Then, in step S209, the emergency sample rack is carried into the rack standby disk 4, and the unprocessed sample waiting for analysis in the rack standby disk 4 is interrupted and carried out to the analyzer 5 or 6 for analysis.
  • the sample rack loader mechanism 1 and the sample rack unloader mechanism 2 are covered in order to prevent foreign matters from being mixed into the sample, and installation and removal of the rack tray is a little troublesome.
  • the rack tray base By returning the rack in the rack tray to the specified position, the rack tray base itself can be moved up and down, and the rack tray base rises when installing and removing the rack tray, making it easier to install the sample rack tray.
  • the loading / unloading line 29 of the rack feeder mechanism 3 for loading / unloading the sample racks to / from the rack standby disk 4 for waiting the sample racks 19 loaded / unloaded to / from the analyzers 5 and 6.
  • the sample rack loader mechanism 1 is provided with the input sample rack tray installation base 21 on which the sample rack tray 18 is installed, and the stored sample rack tray installation base 34 of the sample rack unloader mechanism 2 along one side. Then, the sample rack loader arm 23 moves the sample rack 19 on the sample rack tray 22 installed on the installation base 22 of the sample rack loader mechanism 1 to the loading / unloading line 29, and the sample rack 19 is placed on the rack standby disk 4. Carry in.
  • the sample rack 19 unloaded from the rack standby disk 4 is transported to the vicinity of the sample rack tray 35 installed on the installation base 34 of the sample rack unloader mechanism 2 by the loading / unloading line 29, and by the sample rack unloader mechanism arm 32.
  • the sample is moved into the sample rack tray 35.
  • the sample rack tray 18 Since the sample rack tray 18 is moved into the sample rack tray 35 in this way, the sample rack 19 can be taken out without providing a separate buffer unit.
  • the sample rack loader mechanism 1 moves the rack loader arm 23 to the initial position when carrying out the sample rack 19 to the outside, forms a space so that the sample rack 19 can be added to the sample rack tray 22, and By pushing the sample rack 19 back to the sample rack standby position 46 by the rack return mechanism action point arm 43, the sample rack 19 can be reliably retracted from the loading / unloading line 29, and a separate buffer unit is provided.
  • the sample rack tray 22 can be carried out.
  • the sample rack can be taken out directly from the sample rack tray without providing a separate buffer mechanism, and even if the sample rack remains in the sample rack tray, the sample rack can be removed. It is possible to realize an automatic analyzer that can carry out the tray to the outside and insert an additional sample rack.
  • the input sample rack tray installation base 21 and the storage sample rack tray installation base 34 are arranged along one side of the carry-in / out line 29.
  • a configuration in which the input sample rack tray installation base 21 and the storage sample rack tray installation base 34 are disposed along the carry-out line 29 is also possible.
  • the material of the sample rack loader mechanism arm 23, the sample rack unloader mechanism arm 32, the rack return mechanism force point arm 41, and the rack return mechanism action point arm 43 is not limited as long as it is strong, but is made of metal. It is desirable to be.
  • the input sample rack tray installation base 21 and the storage sample rack tray installation base 34 can be configured to be detachable from the automatic analyzer.
  • SYMBOLS 1 Sample container loading mechanism (sample rack loader mechanism), 2 ... Sample container storage mechanism (sample rack unloader mechanism), 3 ... Rack feeder mechanism, 4 ... Rack standby disk, 5 ... Biochemical analyzer, 6 ... Immunoanalyzer, 7 ... Sampling line, 10 ... Reagent cooler, 12 ... Reaction unit, 13 ... Sampling line, 14 ... Sample sampling mechanism, 15 ... Microcomputer (operation control unit), 16 ... Display unit, 17 ... Reagent cooler, 18 ... Sample rack tray, 19 ... Sample rack, 20 ... Sample rack fall prevention Groove, 21 ... Input sample rack tray installation base, 22 ... Input sample rack tray, 23 ...
  • Sample rack loader mechanism arm 25 ... Sample rack presence / absence detection sensor, 26 ... Rack arrival position to feeder line, 27 ... Sample / sample rack barcode reader, 29 ... Sample rack feeder mechanism loading / unloading line, 31 ... Sample rack feeder mechanism Unloading arrival position, 32 ... Sample rack unloader mechanism arm, 34 ... Stored sample rack tray installation base, 35 ... Stored sample rack tray, 36 ... Stored sample rack, 37 ... Stored sample Rack full sensor, 38 ... Sample rack standby position waiting to be loaded, 40 ... Sample rack loader mechanism arm standby position (home position), 41 ... Rack return mechanism force point arm, 42 ... Rack return mechanism fulcrum, 43 ... Rack return mechanism action point arm, 46 ...
  • Sample rack return operation Specimen rack waiting position for loading, 47 ... Emergency specimen rack loading position (STAT line), 50 ... Unloader arm moving mechanism, 51 ... Loader arm moving mechanism, 60 ... Sample container, 100 ... ⁇ Emergency sample rack presence / absence detection sensor, 300, 301 ... rack tray presence / absence sensor

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The present invention realizes an automatic analysis device whereby a specimen rack can be taken out from a specimen rack tray without a separate buffer mechanism being provided, and loading of an additional specimen rack is possible even when a specimen rack remains in the specimen rack tray. A specimen rack tray installation base of a rack loader mechanism 1 and a specimen rack tray installation base of a rack unloader mechanism 2 are disposed along a carry in/out line of a rack feeder mechanism 3 in a standby disk 4 for specimen racks carried in/out of analysis devices 5, 6. A specimen rack of the specimen rack tray on a mechanism 1 is carried into the disk 4 from the carry in/out line by a specimen rack loader arm 23. The specimen rack carried out from the disk 4 is conveyed to the specimen rack tray on the mechanism 2 in the carry in/out line and moved into the rack tray by the specimen rack unloader mechanism arm 32, and when a specimen rack is to be added, the mechanism 1 moves the rack loader arm 23 to the initial position and forms a vacancy in the specimen rack tray.

Description

自動分析装置Automatic analyzer
　本発明は、血液、尿等の生体試料中の成分を分析する試料を保持する検体ラックを搬送し、その試料を分析ユニットに採取する自動分析装置に関する。 The present invention relates to an automatic analyzer that transports a sample rack that holds a sample for analyzing a component in a biological sample such as blood and urine, and collects the sample in an analysis unit.
　自動分析装置による血漿、血清、尿などの生体試料の分析結果は病状を診断する上で多くの情報をもたらす。 Analysis results of biological samples such as plasma, serum, urine, etc. by automatic analyzers provide a lot of information for diagnosing disease states.
　自動分析装置の構成としては、特許文献１に記載されているように、検体を収容した容器を複数個装填した検体ラックが搬送される検体ラック搬送部に沿って複数の分析ユニット部が配置されている。 As described in Patent Document 1, as an automatic analyzer, a plurality of analysis unit units are arranged along a sample rack transport unit to which a sample rack loaded with a plurality of containers containing samples is transported. ing.
　特許文献１に記載の技術では搬送ラインの左側ではラック供給部を配置し、右側にはラック回収部を配置している。 In the technique described in Patent Document 1, a rack supply unit is disposed on the left side of the transfer line, and a rack collection unit is disposed on the right side.
　臨床検査用の自動分析装置では、特許文献２に記載されているように、検体ラック搬送モジュールの中間位置に検体ラックバッファユニットが設置され、サンプル分注途中の検体ラックと、優先的に分析を行いたい検体が収容された検体ラックとを入れ替えられるようになっている。 In an automatic analyzer for clinical examination, as described in Patent Document 2, a sample rack buffer unit is installed at an intermediate position of the sample rack transport module, and the sample rack in the middle of sample dispensing is preferentially analyzed. The sample rack in which the sample to be performed is stored can be replaced.
　また、特許文献３に記載されているように、検体ラック搬送ラインの中間に位置する検体ラックバッファ機構はループ状のラック待機ディスクとなっており、複数の検体ラックの格納を行い、格納された検体ラックを任意の順番で分析部に送り、任意の順番で検体ラックを収納することができる。 Also, as described in Patent Document 3, the sample rack buffer mechanism located in the middle of the sample rack transport line is a loop-shaped rack standby disk, and stores a plurality of sample racks. The sample racks can be sent to the analysis unit in any order, and the sample racks can be stored in any order.
特開平１１－３１６２３７号公報JP 11-316237 A ＷＯ２０１０／０８７３０３号公報WO2010 / 088733 特開２０００－１０５２４６号公報JP 2000-105246 A
　ここで、特許文献１～３に記載の自動分析装置では、自動分析装置から取り出しが可能な検体ラックトレイから検体ラックを分析部に投入する際は、検体ラック搬入ユニットには上記記載のラック待機ディスク等とは別に、投入する検体ラックトレイの搬送上流側に検体ラックバッファ部が設けられている。 Here, in the automatic analyzers described in Patent Documents 1 to 3, when the sample rack is put into the analyzer from the sample rack tray that can be taken out from the automatic analyzer, the rack standby described above is placed in the sample rack carry-in unit. In addition to the disk or the like, a sample rack buffer unit is provided on the upstream side of the loaded sample rack tray.
　さらに、検体ラックを分析部から回収する際は、検体ラック回収部に検体ラックバッファ部が設けられている。 Furthermore, when the sample rack is collected from the analysis unit, a sample rack buffer unit is provided in the sample rack collection unit.
　そして、ラック供給部及びラック回収部のそれぞれの検体ラックバッファ部に検体ラックを一旦移動させることで、検体ラックトレイの取り出し、及び追加検体の投入を可能としている。 The sample rack is temporarily moved to the respective sample rack buffer units of the rack supply unit and the rack collection unit, so that the sample rack tray can be taken out and an additional sample can be loaded.
　しかし、検体ラック供給部（投入部）と検体ラック回収部（収納部）のそれぞれに検体ラックバッファ部を持たせると、ラック搬送部が大型になってしまう。 However, if each of the sample rack supply unit (input unit) and the sample rack collection unit (storage unit) has a sample rack buffer unit, the rack transport unit becomes large.
　大型の自動分析装置であれば、検体ラックトレイの設置箇所および検体ラックバッファ部をそれぞれ、投入・収納側に設置する領域を確保することは可能であるが、小型の自動分析装置においては、ラック搬送部だけで上記の領域を確保することは困難である。 If it is a large-sized automatic analyzer, it is possible to secure an area for installing the sample rack tray and the sample rack buffer on the input / storage side. It is difficult to secure the above area only by the transport unit.
　このため、投入側の検体ラックバッファ部が無い状態で、検体ラックトレイからの直接投入を自動分析装置に適用した場合、追加検体を投入するためには投入側の検体ラックトレイ内の検体ラックが空になるまで追加検体を投入することが出来ない。 For this reason, when the direct loading from the sample rack tray is applied to the automatic analyzer in the absence of the sample rack buffer on the input side, the sample rack in the sample rack tray on the input side is required to input an additional sample. It is not possible to add additional specimens until they are empty.
　追加検体を緊急検体側から投入することも考えられるが、作業者の作業が煩雑となり、検体の分析効率の低下に繋がることとなる。 Although it is conceivable to introduce an additional sample from the emergency sample side, the operator's work becomes complicated and the analysis efficiency of the sample is reduced.
　本発明の目的は、別箇のバッファ機構を備えることなく、検体ラックトレイから直接検体ラックを取り出すことが可能であり、かつ、検体ラックトレイに検体ラックが残っている場合でも、検体ラックトレイを外部に搬出し、追加の検体ラックの投入を可能とする自動分析装置を実現することである。 An object of the present invention is to provide a sample rack that can be taken out directly from the sample rack tray without providing a separate buffer mechanism, and even if the sample rack remains in the sample rack tray, This is to realize an automatic analyzer that can be carried out and loaded with an additional sample rack.
　上記目的を達成するため、本発明は次のように構成される。 In order to achieve the above object, the present invention is configured as follows.
　自動分析装置において、検体を分析する分析部と、上記分析部に検体容器を保持する検体ラックを搬入し、上記分析部から上記検体容器を搬出する搬入搬出ラインを有する検体ラック搬入搬出機構と、上記検体ラックを架設する検体ラックトレイを着脱可能に設置し、上記検体ラックを上記検体ラック搬入搬出機構の上記搬入搬出ラインに投入する検体容器投入機構と、上記検体ラックトレイを着脱可能に設置し、上記搬入搬出ラインから上記検体ラック回収し収納する検体容器収納機構と、上記分析部、上記検体ラック搬入搬出機構、上記検体容器投入機構、及び検体容器収納機構の動作を制御する動作制御部と、を備える。 In the automatic analyzer, an analysis unit for analyzing a sample, a sample rack loading / unloading mechanism having a loading / unloading line for loading a sample rack holding a sample container into the analysis unit and unloading the sample container from the analysis unit, A sample rack tray for installing the sample rack is detachably installed, a sample container loading mechanism for loading the sample rack into the loading / unloading line of the sample rack loading / unloading mechanism, and the sample rack tray are detachably installed. A sample container storage mechanism that collects and stores the sample rack from the load / unload line, and an operation control unit that controls operations of the analyzer, the sample rack load / unload mechanism, the sample container input mechanism, and the sample container storage mechanism. .
　別箇のバッファ機構を備えることなく、検体ラックトレイから直接検体ラックを取り出すことが可能であり、かつ、検体ラックトレイに検体ラックが残っている場合でも、検体ラックトレイを外部に搬出し、追加の検体ラックの投入を可能とする自動分析装置を実現することができる。 Without providing a separate buffer mechanism, the sample rack can be taken out directly from the sample rack tray, and even if the sample rack remains in the sample rack tray, the sample rack tray is taken out and added. Thus, it is possible to realize an automatic analyzer that can input the sample rack.
本発明の一実施例が適用される自動分析装置の全体構成図である。1 is an overall configuration diagram of an automatic analyzer to which an embodiment of the present invention is applied. 本発明の一実施例における検体容器投入機構に設置される検体ラックトレイの概略斜視図である。It is a schematic perspective view of the sample rack tray installed in the sample container loading mechanism in one embodiment of the present invention. 本発明の一実施例における検体ラックローダ機構による検体ラックの搬入動作説明図である。FIG. 6 is an explanatory diagram of a sample rack loading operation by a sample rack loader mechanism in an embodiment of the present invention. 本発明の一実施例におけるラックアンローダ機構の搬出動作簡略説明図である。It is a carrying-out simplified explanatory drawing of the rack unloader mechanism in one Example of this invention. 本発明の一実施例におけるラックローダ機構のラックトレイ搬出動作簡略説明図である。It is a simplified explanatory view of the rack tray carry-out operation of the rack loader mechanism in one embodiment of the present invention. 本発明の一実施例におけるラック緊急レーン（ＳＴＡＴレーン）からラック投入をしたときの搬入動作簡略説明図である。FIG. 6 is a simplified explanatory view of a loading operation when a rack is loaded from a rack emergency lane (STAT lane) in one embodiment of the present invention. 本発明の一実施例における検体ラック追加投入／検体ラックトレイ取り出しを示したフローチャートである。6 is a flowchart showing additional sample rack loading / sample rack tray removal in an embodiment of the present invention. 本発明の一実施例における追加検体ラックを投入完了指示したときの検体ラックローダ機構・検体ラックアンローダ機構における動作論理を示したフローチャートである。6 is a flowchart showing the operation logic in the sample rack loader mechanism / sample rack unloader mechanism when an instruction to complete loading of an additional sample rack is given in an embodiment of the present invention. 本発明の一実施例における緊急検体ラックをＳＴＡＴラインより投入指示したときのラックローダ機構・ラックアンローダ機構における動作論理を示したフローチャートである。6 is a flowchart showing the operation logic in the rack loader mechanism / rack unloader mechanism when an emergency sample rack is instructed to be inserted from the STAT line in one embodiment of the present invention.
　以下、添付図面を参照して、本発明の実施形態について説明する。 Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.
　なお、本発明の実施形態を説明するための全図において同一機能を有するものは原則として同一の符号を付すようにし、その繰り返しの説明は可能な限り省略するようにしている。 Note that components having the same function are denoted by the same reference symbols throughout the drawings for describing the embodiments of the present invention, and repeated description thereof is omitted as much as possible.
　図１は、本発明の一実施例が適用される自動分析装置の全体構成図である。 FIG. 1 is an overall configuration diagram of an automatic analyzer to which one embodiment of the present invention is applied.
　図１において、自動分析装置は、検体容器投入機構（検体ラックローダ機構）１と、検体容器収納機構（検体ラックアンローダ機構）２と、ラックフィーダ機構３の緊急検体ラック投入機構を装置前面に備えている。 In FIG. 1, the automatic analyzer includes a sample container loading mechanism (sample rack loader mechanism) 1, a sample container storage mechanism (sample rack unloader mechanism) 2, and an emergency sample rack loading mechanism of a rack feeder mechanism 3 on the front surface of the apparatus. ing.
　検体容器投入機構（検体ラックローダ機構）１、検体容器収納機構（検体ラックアンローダ機構）２、ラックフィーダ機構３を介してラック待機ディスク４に検体ラックの出し入れを行う。 The sample rack is loaded into and removed from the rack standby disk 4 via the sample container loading mechanism (sample rack loader mechanism) 1, the sample container storage mechanism (sample rack unloader mechanism) 2, and the rack feeder mechanism 3.
　検体容器投入機構１、検体容器収納機構２、及びラックフィーダ機構３の左右側に分析装置を接続できるようになっており、図１では右側に生化学分析装置５が配置され、左側には免疫分析装置６が配置されている。この配置に限らず、検体容器投入機構１、検体容器収納機構２、及びラックフィーダ機構３の左側に生化学分析装置が配置され、右側に免疫分析装置が配置される構成や、左右両側の分析装置が共に生化学分析装置、もしくは共に免疫分析装置となっていても良い。 An analyzer can be connected to the left and right sides of the specimen container loading mechanism 1, the specimen container storage mechanism 2, and the rack feeder mechanism 3. In FIG. 1, a biochemical analyzer 5 is arranged on the right side, and an immunity is placed on the left side. An analyzer 6 is arranged. Not only this arrangement, but also a configuration in which the biochemical analyzer is arranged on the left side of the specimen container loading mechanism 1, the specimen container storage mechanism 2, and the rack feeder mechanism 3, and the immunological analyzer is arranged on the right side, and analysis on both the left and right sides Both devices may be biochemical analyzers or both immunoassays.
　検体容器投入機構１及び検体容器収納機構２は、ラック待機ディスク４を介して両サイドの分析装置５及び６に独立して検体ラックを供給・収納可能となっている。生化学分析装置５は、主たる構成部として、サンプリングライン７、試薬保冷庫１０、反応部１２を備えている。 The sample container loading mechanism 1 and the sample container storage mechanism 2 can supply and store the sample racks independently through the rack standby disk 4 to the analyzers 5 and 6 on both sides. The biochemical analyzer 5 includes a sampling line 7, a reagent cool box 10, and a reaction unit 12 as main components.
　また、免疫分析装置６は、主たる構成部として、サンプリングライン１３、検体サンプリング機構１４、試薬保冷庫１７を備えている。ただし、図１には示していないが、生化学分析装置５及び免疫分析装置６は、他の構成部を備えている。 Further, the immune analyzer 6 includes a sampling line 13, a sample sampling mechanism 14, and a reagent cold storage 17 as main components. However, although not shown in FIG. 1, the biochemical analyzer 5 and the immune analyzer 6 include other components.
　また、検体容器投入機構１は、検体ラックローダ機構アーム２３と、ラック戻し機構作用点アーム（ラック戻しアーム）４３と備える。また、検体容器収納機構２は、検体ラックアンローダ機構アーム３２を備えている。また、ラック戻し機構作用点アーム４３及び検体ラックアンローダ機構アーム３２を駆動するラック戻し機構力点アーム４１が、ラックフィーダ機構３を間にして検体容器投入機構１及び検体容器収納機構２の近傍に配置されている。 The sample container loading mechanism 1 includes a sample rack loader mechanism arm 23 and a rack return mechanism action point arm (rack return arm) 43. The sample container storage mechanism 2 includes a sample rack unloader mechanism arm 32. A rack return mechanism force point arm 41 for driving the rack return mechanism action point arm 43 and the sample rack unloader mechanism arm 32 is disposed in the vicinity of the sample container loading mechanism 1 and the sample container storage mechanism 2 with the rack feeder mechanism 3 interposed therebetween. Has been.
　さらに、自動分析装置全体の動作を制御する動作制御部であるマイクロコンピュータ１５と、表示部１６が備えられている。つまり、マイクロコンピュータ１５は、分析部（生化学分析装置５及び免疫分析装置６）、検体ラック搬入搬出機構（ラックフィーダ機構３）、検体容器投入機構１、及び検体容器収納機構２の動作を制御する。 Furthermore, a microcomputer 15 which is an operation control unit for controlling the operation of the entire automatic analyzer and a display unit 16 are provided. That is, the microcomputer 15 controls the operations of the analysis unit (the biochemical analysis device 5 and the immunological analysis device 6), the sample rack loading / unloading mechanism (rack feeder mechanism 3), the sample container loading mechanism 1, and the sample container storage mechanism 2. To do.
　図２は、検体容器投入機構１又は検体容器収納機構２に設置される検体ラックトレイ１８の概略斜視図である。 FIG. 2 is a schematic perspective view of the sample rack tray 18 installed in the sample container loading mechanism 1 or the sample container storage mechanism 2.
　図２において、検体ラックトレイ１８は、複数の検体ラック１９を検体ラックトレイ１８に架設して持ち運びを行えるようになっている。検体ラックトレイ１８のラック設置部には、検体ラック１９に形成された検体ラック転倒防止溝２０に挿入可能な突起部が形成されており、検体ラックトレイ１８からの検体ラック１９の搬送時および、検体ラックトレイ１８の持ち運び時に検体ラック１９が転倒しないような構造となっている。 In FIG. 2, the sample rack tray 18 is constructed such that a plurality of sample racks 19 are installed on the sample rack tray 18 and can be carried. The rack mounting portion of the sample rack tray 18 is formed with a protrusion that can be inserted into the sample rack overturn prevention groove 20 formed in the sample rack 19, and when the sample rack 19 is transported from the sample rack tray 18, The structure is such that the sample rack 19 does not fall over when the sample rack tray 18 is carried.
　さらに、検体ラックトレイ１８を持ち上げると検体ラックトレイ１８の左右の取手部が上方に稼動し、検体ラックトレイ１８の持ち運び時には検体ラック１９が検体ラックロレイ１８から抜け落ちない構造となっている。 Further, when the sample rack tray 18 is lifted, the left and right handle portions of the sample rack tray 18 operate upward, and the sample rack 19 is prevented from falling out of the sample rack tray 18 when the sample rack tray 18 is carried.
　図３は、検体容器投入機構である検体ラックローダ機構１の検体ラック１９の搬入動作説明図である。 FIG. 3 is an explanatory view of the loading operation of the sample rack 19 of the sample rack loader mechanism 1 which is a sample container loading mechanism.
　図３おいて、検体ラックローダ機構１は、検体ラックトレイ18を着脱可能な投入検体ラックトレイ設置ベース２１を備えており、検体容器６０を保持する検体ラック１９を架設した投入検体ラックトレイ２２を検体ラックトレイ設置ベース２１へ架設することで、検体ラックトレイ２２による検体ラック１９の架設を可能とする。 In FIG. 3, the sample rack loader mechanism 1 includes an input sample rack tray installation base 21 to which a sample rack tray 18 can be attached and detached, and an input sample rack tray 22 on which a sample rack 19 holding a sample container 60 is installed. By installing on the sample rack tray installation base 21, the sample rack 19 can be installed by the sample rack tray 22.
　また、このラックトレイ設置ベース２１には検体ラックトレイ２２が架設されているかどうかを検知するラックトレイ有無センサ３００が取り付けられており、検体ラック１９の投入が可能かどうかを確認することが出来るようになっている。 Further, a rack tray presence / absence sensor 300 for detecting whether or not the sample rack tray 22 is installed is attached to the rack tray installation base 21 so that it can be confirmed whether or not the sample rack 19 can be loaded. It has become.
　投入検体ラック１９が検体ラックトレイ２２に架設されると、ローダアーム移動機構５１により移動される検体ラックローダ機構アーム２３により検体ラックローダ機構アーム２３のラック送り出し動作方向２４へ検体ラック１９が送り出される。検体ラック有無検知センサ（フィーダラインへのラック到達センサ）２５が、検体ラックフィーダ機構搬入搬出ライン２９を間にして検体ラックトレイ２２が設定された箇所と反対側に配置されている。 When the input sample rack 19 is installed on the sample rack tray 22, the sample rack 19 is sent out in the rack feed operation direction 24 of the sample rack loader mechanism arm 23 by the sample rack loader mechanism arm 23 moved by the loader arm moving mechanism 51. . A sample rack presence / absence detection sensor (rack arrival sensor to feeder line) 25 is disposed on the opposite side of the position where the sample rack tray 22 is set with the sample rack feeder mechanism loading / unloading line 29 in between.
　検体ラック有無検知センサ２５が、検体ラック１９が搬入搬出ライン２９上に位置することを検知すると、検体ラックローダ機構アーム２３の検体ラック１９の送り出し動作が停止する。 When the sample rack presence / absence detection sensor 25 detects that the sample rack 19 is positioned on the loading / unloading line 29, the feeding operation of the sample rack 19 of the sample rack loader mechanism arm 23 is stopped.
　そして、検体ラックフィーダ機構搬入搬出ライン２９のラック到達位置２６に到達した一つの検体ラック１９が、ラックフィーダ機構３により運ばれ、検体・検体ラックバーコードリーダ２７でラックバーコードおよび検体のバーコードが読み取され、検体ラックフィーダ機構投入軌道（垂直方向）２８へ移動し、検体ラックフィーダ機構搬入搬出ライン２９からラック待機ディスク４に搬入される。 Then, one sample rack 19 that has reached the rack arrival position 26 of the sample rack feeder mechanism loading / unloading line 29 is carried by the rack feeder mechanism 3, and a rack barcode and a sample barcode are scanned by the sample / sample rack barcode reader 27. Is read, moved to the sample rack feeder mechanism loading trajectory (vertical direction) 28, and loaded into the rack standby disk 4 from the sample rack feeder mechanism loading / unloading line 29.
　検体・検体ラックバーコードリーダ２７には、検体を収容する試験管の高さを検知するセンサが取り付けてあり、試験管高さ情報を把握することで、検体分注動作のパラメータとして使用できる。検体・検体ラックバーコードリーダ２７自体で試験管情報（試験管径・試験管高さ・試験管キャップ形状・試験管キャップカラー）を読み取っても良い。 The sample / sample rack barcode reader 27 is provided with a sensor for detecting the height of the test tube containing the sample, and can be used as a parameter for sample dispensing operation by grasping the test tube height information. The test tube information (test tube diameter, test tube height, test tube cap shape, test tube cap color) may be read by the sample / sample rack barcode reader 27 itself.
　図４は、検体ラック１９をラック待機ディスク４から検体容器収納機構２に戻すラック戻し機構におけるラックアンローダ機構２のリセット動作簡略説明図である。ラックアンローダ機構（検体容器収納機構）２は、検体ラックトレイ１８を着脱可能な収納検体ラックトレイ設置ベース３４を備えている。 FIG. 4 is a simplified explanatory diagram of the reset operation of the rack unloader mechanism 2 in the rack return mechanism that returns the sample rack 19 from the rack standby disk 4 to the sample container storage mechanism 2. The rack unloader mechanism (sample container storage mechanism) 2 includes a storage sample rack tray installation base 34 to which the sample rack tray 18 can be attached and detached.
　図４において、ラックアンローダ機構２のリセット動作時には、アンローダアーム移動機構５０により検体ラックアンローダ機構アーム３２が図４の位置まで移動される。 In FIG. 4, when the rack unloader mechanism 2 is reset, the unloader arm moving mechanism 50 moves the sample rack unloader mechanism arm 32 to the position shown in FIG.
　そして、ラック待機ディスク４から検体ラックフィーダ機構搬出駆動方向（図４の下方向）３０に排出された検体ラック１９が、検体ラックフィーダ機構搬出口到達ポジション３１に到達すると、これを検知するセンサ（図示せず）により検知されることにより、アンローダアーム移動機構５０により検体ラックアンローダ機構アーム３２が図４に示す状態から検体ラックアンローダ機構アーム搬出動作駆動方向（図４の左から右への方向であり、検体ラック１９を搬入搬送ライン２９上から検体ラックトレイ３５上に移動する方向）３３に移動し、検体ラック１９を移動する。 When the sample rack 19 discharged from the rack standby disk 4 in the sample rack feeder mechanism unloading drive direction (downward in FIG. 4) reaches the sample rack feeder mechanism unloading arrival position 31, a sensor ( 4, the unloader arm moving mechanism 50 causes the sample rack unloader mechanism arm 32 to move from the state shown in FIG. 4 to the sample rack unloader mechanism arm unloading operation driving direction (from left to right in FIG. 4). Yes, the sample rack 19 is moved in the direction 33) in which the sample rack 19 is moved from the carry-in conveyance line 29 to the sample rack tray 35), and the sample rack 19 is moved.
　そして、収納検体ラックトレイ設置ベース３４に架設されている収納検体ラックトレイ３５内に検体ラック１９を回収して収納する。収納検体ラックトレイ設置ベース３４には、収納検体ラックトレイ３５が収納検体ラックトレイ設置ベース３４に架設されているか否かを検知するラックトレイ有無センサ３０１が取付けられている。 Then, the sample rack 19 is collected and stored in the storage sample rack tray 35 installed on the storage sample rack tray installation base 34. A rack tray presence / absence sensor 301 for detecting whether or not the stored sample rack tray 35 is installed on the stored sample rack tray installation base 34 is attached to the stored sample rack tray installation base 34.
　収納検体ラックトレイ３５内の収納済み検体ラック３６は、次に収納検体ラックトレイ３５に収納される検体ラックにより押され、収納検体ラックトレイ３５のスペースがある奥へと架設され、収納検体ラック満杯センサ３７の検知が入るまで収納することができる。 The stored sample rack 36 in the stored sample rack tray 35 is pushed by the next sample rack stored in the stored sample rack tray 35, and is erected to the back where there is space in the stored sample rack tray 35, so that the stored sample rack is full. It can be stored until the sensor 37 is detected.
　検知容器収納機構２の収納検体ラックトレイ３５内の収納済み検体ラック３６は、別箇のラックバッファ部を設けることなく、外部に取り出すことが可能である。 The stored sample rack 36 in the stored sample rack tray 35 of the detection container storage mechanism 2 can be taken out without providing a separate rack buffer unit.
　投入検体ラックトレイ２２においては、検体ラックフィーダ機構搬入搬出ライン２に最接近した位置である投入待ち検体ラック待機位置３８に検体ラック１９が位置し、検体ラック１９が検体ラックフィーダ機構搬入搬出ライン２９により搬送されないように構成されている。 In the input sample rack tray 22, the sample rack 19 is positioned at the input waiting sample rack standby position 38 that is the position closest to the sample rack feeder mechanism carry-in / out line 2, and the sample rack 19 is in the sample rack feeder mechanism carry-in / out line 29. It is comprised so that it may not be conveyed by.
　図５は、ラックローダ機構１のラックトレイ搬出動作簡略説明図である。図５において、投入検体ラックトレイ２２に検体ラック１９が残っている状態で、検体ラック１９の追加投入を行うために投入検体ラックトレイ２２を取り出す際、検体ラック１９が投入検体ラックトレイ２２とラックフィーダ機構部３との境界部に検体ラックが来てしまっているため、投入検体ラックトレイ２２へ検体ラック１９を押し戻す必要がある。 FIG. 5 is a simplified explanatory view of the rack tray unloading operation of the rack loader mechanism 1. In FIG. 5, when the input sample rack tray 22 is taken out for additional input of the sample rack 19 in a state where the sample rack 19 remains in the input sample rack tray 22, the sample rack 19 and the input sample rack tray 22 Since the sample rack has come to the boundary with the feeder mechanism unit 3, it is necessary to push the sample rack 19 back to the input sample rack tray 22.
　投入検体ラックトレイ２２を取り出さずに１検体ラック１９ずつ、架設された投入検体ラックトレイ２２に検体ラック１９を供給する場合においても、投入検体ラックトレイ２２に残っていた検体ラック１９を誤って押してしまうと、ラックフィーダ機構３の搬送ライン側に検体ラック１９が飛び出してしまい、ＳＴＡＴ（緊急検体）投入の妨げとなる可能性がある。 Even when the sample rack 19 is supplied to the installed input sample rack tray 22 for each sample rack 19 without taking out the input sample rack tray 22, the sample rack 19 remaining on the input sample rack tray 22 is erroneously pushed. If this happens, the sample rack 19 may jump out to the transport line side of the rack feeder mechanism 3, which may hinder the introduction of STAT (emergency sample).
　このため、検体ラック１９追加後にトレイ２２へ検体ラック１９を押し戻しておく必要がある。 Therefore, it is necessary to push the sample rack 19 back to the tray 22 after the sample rack 19 is added.
　ラックローダ機構アーム２３が検体ラック１９を搬入搬出ライン２９側に押し続けている状態では検体ラック１９をラックトレイ２２の規定位置に戻すことは出来ない。このため、まず、ラックローダ機構アーム２３を初期位置へ戻す必要がある。検体ラックローダ機構アーム２３をリセット動作方向（ラック送り出し動作方向２４とは反対方向）３９に移動し、検体ラックローダ機構アーム待機位置（ホームポジション）４０へ移動する。 When the rack loader mechanism arm 23 continues to push the sample rack 19 toward the loading / unloading line 29, the sample rack 19 cannot be returned to the specified position on the rack tray 22. For this reason, it is first necessary to return the rack loader mechanism arm 23 to the initial position. The sample rack loader mechanism arm 23 is moved in the reset operation direction (direction opposite to the rack delivery operation direction 24) 39 and moved to the sample rack loader mechanism arm standby position (home position) 40.
　検体ラック１９を規定位置に戻すという観点ではラックローダ機構アーム２３は検体ラックローダ機構アーム待機位置（ホームポジション）４０まで戻らず、１検体ラック分だけラック検体ラックローダ機構アームリセット動作方向３９へ移動してもラック戻し動作自体は出来るが、検体ラックトレイ２２の取り出し、再投入を考慮すると、検体ラックローダ機構アーム待機位置（ホームポジション）４０まで戻ることが望ましい。 From the viewpoint of returning the sample rack 19 to the specified position, the rack loader mechanism arm 23 does not return to the sample rack loader mechanism arm standby position (home position) 40 and moves in the rack sample rack loader mechanism arm reset operation direction 39 by one sample rack. Even if the rack return operation itself can be performed, it is desirable to return to the sample rack loader mechanism arm standby position (home position) 40 in consideration of taking out and reinserting the sample rack tray 22.
　ラック戻し機構はラック戻し機構力点アーム４１が、ラック戻し機構支点４２中心として、ラック戻し機構作用点アーム４３と接続されており、ラック戻し機構力点アーム４１が、アンローダアーム移動機構５０により移動されるラックアンローダ機構アーム３２が移動してこのラックアンローダ機構アーム３２から力を受ける方向（駆動方向３３とは反対方向の動作方向）４４に押されることで、検体ラックアンローダ機構アーム３２の動作に合わせて、ラック戻し機構作用点アーム４３が戻し動作方向（検体ラックトレイ２２上の検体ラック１９を検体ラック搬入搬送機構３の搬入搬出ライン２９から離れる方向）４５へ移動するように動作する。 In the rack return mechanism, the rack return mechanism force point arm 41 is connected to the rack return mechanism action point arm 43 with the rack return mechanism fulcrum 42 as the center, and the rack return mechanism force point arm 41 is moved by the unloader arm moving mechanism 50. The rack unloader mechanism arm 32 moves and is pushed in a direction (operation direction opposite to the drive direction 33) 44 that receives a force from the rack unloader mechanism arm 32. The rack return mechanism operating point arm 43 operates so as to move in the return operation direction 45 (the direction in which the sample rack 19 on the sample rack tray 22 moves away from the loading / unloading line 29 of the sample rack loading / unloading mechanism 3) 45.
　この一連のラック戻し動作を行うことで、検体ラックトレイ２２上の規定の投入待ち検体ラック待機位置４６へ検体ラック１９を戻すことができる。その後、ラック戻し機構４３はホームポジション（図６に示す位置）に戻る。なお、駆動軸数を増やしてラック戻し機構を独立して別個で動作させても良い。 By performing this series of rack return operations, the sample rack 19 can be returned to the specified input waiting sample rack standby position 46 on the sample rack tray 22. Thereafter, the rack return mechanism 43 returns to the home position (position shown in FIG. 6). The rack return mechanism may be independently operated separately by increasing the number of drive shafts.
　検体ラックトレイ２２を外部に搬出し、検体ラックトレイ２２への検体ラック１９の追加投入後に、検体ラックトレイ２２を投入検体ラックトレイ設置ベース２１に設置後、ラックフィーダ機構３の一本の搬送ライン（搬入搬出ライン２９）まで検体ラック１９を送り、その後、上述したようなラック戻し機構作用点アーム４３により、図５に示すような位置までラック戻し動作を行うことで、操作者の手で検体ラック１９をラックトレイ２２への追加投入を行う際、誤って既に架設されている検体ラック１９を一本の搬送ライン側へ押し出してしまったとしても、検体ラック位置を規定の位置へリセットさせることができる。 The sample rack tray 22 is unloaded, and after the sample rack 19 is additionally loaded into the sample rack tray 22, the sample rack tray 22 is loaded on the loaded sample rack tray installation base 21, and then one conveyance line of the rack feeder mechanism 3. The sample rack 19 is sent to the (loading / unloading line 29), and then the rack returning operation is performed to the position as shown in FIG. When the rack 19 is additionally loaded into the rack tray 22, the sample rack position is reset to a specified position even if the sample rack 19 already installed is accidentally pushed out to one transport line side. Can do.
　また、一本の搬送ラインにはラック有無検知センサ２５が設置されており、検体ラックトレイ２２を取り出し、搬出検体ラック１９を追加して再設置し、その後に、上記ラック戻し動作を行うことで、ラック有無検知センサ２５による検体ラック検知タイミングにおける検体ラックローダ機構アーム２３の送り量をマイクロコンピュータ１５が算出すると、算出した送り量から投入された検体ラック１９の数を算出して把握できることができる。 In addition, a rack presence / absence detection sensor 25 is installed in one transport line, the sample rack tray 22 is taken out, the unloaded sample rack 19 is added and reinstalled, and then the rack return operation is performed. When the microcomputer 15 calculates the feed amount of the sample rack loader mechanism arm 23 at the sample rack detection timing by the rack presence / absence detection sensor 25, the number of sample racks 19 loaded can be calculated and grasped from the calculated feed amount. .
　上記のような構成により、別箇にバッファ部を設けることなく、検体ラックトレイ２２に検体ラック１９を追加投入することができる。 With the configuration as described above, the sample rack 19 can be additionally supplied to the sample rack tray 22 without providing a separate buffer unit.
　図６は、緊急ラックレーン（ＳＴＡＴレーン）からラック投入をしたときの搬入動作簡略説明図である。 FIG. 6 is a simplified explanatory diagram of the loading operation when the rack is loaded from the emergency rack lane (STAT lane).
　図６において、緊急検体ラック投入位置（ＳＴＡＴレーン）４７へ緊急検体が設置されると、緊急検体ラック投入位置（ＳＴＡＴレーン）４７の緊急検体ラック有無検知センサ１００が反応し、マイクロコンピュータ１５の操作部へ緊急検体の搬入が可能か問い合わせを行う。 In FIG. 6, when an emergency sample is installed at the emergency sample rack loading position (STAT lane) 47, the emergency sample rack presence / absence detection sensor 100 at the emergency sample rack loading position (STAT lane) 47 reacts to operate the microcomputer 15. Ask the department if it is possible to carry in an emergency sample.
　ラック待機ディスク４の空き及び、ローダ機構・アンローダ機構の稼動状況を確認し、搬入可能の信号を受け取ると、緊急検体ラック投入部駆動方向４８、へ緊急検体を投入し、検体・検体ラックバーコードリーダ２７がラックバーコード・検体バーコードを読み取って緊急検体ラックをラック待機ディスク４へ投入する。 Upon confirming the availability of the rack standby disk 4 and the operating status of the loader mechanism / unloader mechanism and receiving a signal that can be carried in, the emergency sample is loaded into the emergency sample rack loading unit drive direction 48, and the sample / sample rack barcode The reader 27 reads the rack barcode / sample barcode and puts the emergency sample rack into the rack standby disk 4.
　次に、図１の自動分析装置における制御系について説明する。 Next, the control system in the automatic analyzer shown in FIG. 1 will be described.
　上記マイクロコンピュータ（動作制御部）１５は、インターフェイスを介して、サンプル分注・試薬分注・洗浄水ポンプの制御を行う。また、マイクロコンピュータ１５は、検体ラック投入・収納ユニットの制御も行い、ラック待機ディスク４に対して、検体ラック１９の搬入・搬出をコントロールすることで、未処理検体ラック１９による渋滞が起きないように制御する。また、マイクロコンピュータ１５は、緊急検体を迅速に測定できるように制御する。 The microcomputer (operation control unit) 15 controls the sample dispensing / reagent dispensing / washing water pump via the interface. The microcomputer 15 also controls the sample rack loading / unloading unit, and controls the loading / unloading of the sample rack 19 with respect to the rack standby disk 4 so that the unprocessed sample rack 19 is not congested. To control. Moreover, the microcomputer 15 controls so that an emergency sample can be measured rapidly.
　次に、図１の自動分析装置におけるサンプルの分析動作を説明する。 Next, the sample analysis operation in the automatic analyzer shown in FIG. 1 will be described.
　自動分析装置によって分析可能な項目に関する分析パラメータは、予めタッチパネル等の情報入力装置である表示部１６を介してマイクロコンピュータ１５に入力されておリ、記憶媒体に記憶されている。操作者は、マイクロコンピュータ１５に接続された表示部１６の操作機能画面を用いて各サンプルに依頼されている検査項目を選択する。 Analytical parameters relating to items that can be analyzed by the automatic analyzer are previously input to the microcomputer 15 via the display unit 16 that is an information input device such as a touch panel and stored in a storage medium. The operator uses the operation function screen of the display unit 16 connected to the microcomputer 15 to select the inspection item requested for each sample.
　図７は、検体ラック追加投入／検体ラックトレイ取り出しを示したフローチャートである。 FIG. 7 is a flowchart showing sample rack additional input / sample rack tray removal.
　図７のステップＳ１において、操作者が検体ラック追加投入／検体ラックトレイ取り出しを指示すると、動作制御部であるマイクロコンピュータ１５はラックローダ・ラックアンローダ機構のリセット動作を行う。検体ラックの追加投入指示は表示部１６（タッチパネル等）から入力を行う。押しボタンをそれぞれの機構付近に設置して指示するようにしても良い。 In step S1 of FIG. 7, when the operator gives an instruction to add a sample rack / take out a sample rack tray, the microcomputer 15 as the operation control unit performs a reset operation of the rack loader / rack unloader mechanism. An instruction to add a sample rack is input from the display unit 16 (such as a touch panel). You may make it instruct | indicate by installing a push button near each mechanism.
　ステップＳ２において、ラックフィーダ機構３のラック搬送を行うラックキャリア位置が、ホームポジションにあるかどうかを確認し、ホームポジション以外の場合はステップＳ３のラックフィーダ機構３のラック搬入搬出動作を継続し、処理途中であった１ラック分の処理が完了したらホームポジションへ移動する。ここで、ホームポジションとは、緊急検体ラック投入位置に配置された緊急検体ラック以外について、図６に示した位置を示す。 In step S2, it is confirmed whether or not the rack carrier position for carrying the rack of the rack feeder mechanism 3 is in the home position. If the rack carrier position is other than the home position, the rack carrying in / out operation of the rack feeder mechanism 3 in step S3 is continued. When processing for one rack, which was in the middle of processing, is completed, it moves to the home position. Here, the home position indicates the position shown in FIG. 6 except for the emergency sample rack arranged at the emergency sample rack loading position.
　ステップＳ２において、ラックフィーダ機構３のラック搬送を行うラックキャリア位置が、ホームポジションにある場合は、ステップＳ４に進む。 In step S2, when the rack carrier position for carrying the rack of the rack feeder mechanism 3 is in the home position, the process proceeds to step S4.
　ステップＳ４において、検体ラックアンローダ機構２におけるアンローダ機構アーム３２のアーム位置確認を行い、ホームポジションに無い場合はステップＳ５のアンローダ機構アーム３２のホームポジションへの移動を行い、検体ラックアンローダ機構２から処理済みの検体ラックトレイ３５を取り出せる状態にする。 In step S4, the arm position of the unloader mechanism arm 32 in the sample rack unloader mechanism 2 is confirmed. If the arm position is not at the home position, the unloader mechanism arm 32 is moved to the home position in step S5 and processed from the sample rack unloader mechanism 2. The ready sample rack tray 35 is made ready for removal.
　ステップＳ４において、アンローダ機構アーム３２のアーム位置がホームポジションにある場合は、ステップＳ６に進む。ステップＳ６において、検体ラックローダ機構１の検体ラックローダ機構アーム２３をホームポジション４０へ移動し、ラック戻し動作を行える状態にする。そして、ステップＳ７に進み、ラック戻し動作を行う。 In step S4, when the arm position of the unloader mechanism arm 32 is at the home position, the process proceeds to step S6. In step S6, the sample rack loader mechanism arm 23 of the sample rack loader mechanism 1 is moved to the home position 40 so that the rack return operation can be performed. In step S7, the rack return operation is performed.
　このラック戻し動作により、検体ラックトレイ２２とフィーダ機構３の境界にきてしまっている検体ラック１９を規定位置に戻し、ラックローダ機構３から未処理・もしくは空の検体ラックトレイ２２を取り出せる状態にする。そして、ステップＳ８に進み、検体ラック１９の追加投入が可能状態になったことを、マイクロコンピュータ１５に接続された表示部１６（タッチパネルモニタもしくはＬＥＤ）で表示をし、ステップＳ９の指示待ち状態へと遷移する。 By this rack return operation, the sample rack 19 that has come to the boundary between the sample rack tray 22 and the feeder mechanism 3 is returned to the specified position, and an unprocessed or empty sample rack tray 22 can be taken out from the rack loader mechanism 3. To do. In step S8, the display unit 16 (touch panel monitor or LED) connected to the microcomputer 15 displays that the additional loading of the sample rack 19 is possible, and enters an instruction waiting state in step S9. And transition.
　図８は、追加検体ラックを投入完了指示したときの検体ラックローダ機構１・検体ラックアンローダ機構２における動作論理を示したフローチャートである。 FIG. 8 is a flowchart showing the operation logic in the sample rack loader mechanism 1 and the sample rack unloader mechanism 2 when an instruction to complete the addition of the additional sample rack is given.
　操作者による検体ラック１９もしくは検体ラックトレイ１８の投入が完了した後、ステップＳ１０１において、操作者は、検体ラック投入完了指示・検体ラックトレイ完了指示を表示部１６のタッチパネルもしくは押しボタンで行う。投入完了の指示が出されると、動作制御部であるマイクロコンピュータ１５は、ステップＳ１０２において、ラックトレイ有無センサ３００及び３０１のＯＮ－ＯＦＦを確認し、ＯＦＦの場合は、ステップＳ１０３に進み、表示部１６にトレイ無しアラームを表示する。 After the operator completes the loading of the sample rack 19 or the sample rack tray 18, in step S101, the operator gives a sample rack loading completion instruction / sample rack tray completion instruction with the touch panel or push button of the display unit 16. When an instruction for completion of insertion is issued, the microcomputer 15 as the operation control unit confirms the ON / OFF of the rack tray presence / absence sensors 300 and 301 in step S102. If OFF, the process proceeds to step S103, and the display unit 16 displays a tray out alarm.
　ステップＳ１０２において、検体ラックトレイがある場合はステップＳ１０４に進み、検体ラックローダ機構アーム２３をラックフィーダライン（検体ラックフィーダ機構搬入搬出ライン）２９側へ移動する。そして、ステップＳ１０５において、ラックフィーダライン２９の近傍に設置されている検体ラック有無検知センサ２５で検体ラック１９が到達したかの検知を行う。検体ラックローダ機構アーム２３による検体ラック送りが完了しても、検体ラック有無検知センサ２５がＯＦＦのままの場合は、ステップＳ１０６に進み、ラック無しアラームを表示部１６に表示する。 If there is a sample rack tray in step S102, the process proceeds to step S104, and the sample rack loader mechanism arm 23 is moved to the rack feeder line (sample rack feeder mechanism loading / unloading line) 29 side. In step S105, the sample rack presence / absence detection sensor 25 installed in the vicinity of the rack feeder line 29 detects whether the sample rack 19 has arrived. If the sample rack presence / absence detection sensor 25 remains OFF even after the sample rack feeding by the sample rack loader mechanism arm 23 is completed, the process proceeds to step S106, and a no rack alarm is displayed on the display unit 16.
　ステップＳ１０５において、ラック到達センサ２５がＯＮとなれば、ステップＳ１０７に進み、検体ラックローダ機構アーム２３の移動を停止する。検体ラックローダ機構アーム２３の停止位置をアーム送り量で調べることで検体ラックローダ機構１に検体ラック１９が何ラック保持されているか把握することができる。 If the rack arrival sensor 25 is turned on in step S105, the process proceeds to step S107, and the movement of the sample rack loader mechanism arm 23 is stopped. By checking the stop position of the sample rack loader mechanism arm 23 by the arm feed amount, it is possible to grasp how many sample racks 19 are held in the sample rack loader mechanism 1.
　その後、ステップＳ１０８のラック戻し動作を実行する。そして、ステップＳ１０９で次指示を待つ状態へと遷移する。 Thereafter, the rack return operation in step S108 is executed. And it changes to the state which waits for the next instruction | indication in step S109.
　なお、検体ラック１９をそのまま投入する場合は、ステップＳ１０８のラック戻し動作自体は省略できる場合もあるが、次の動作が検体ラックローダ機構１からの検体ラック１９の搬入では無く、緊急検体ラックの搬入やラックアンローダ機構２への検体ラック搬出の場合、ラックフィーダ機構３の稼動領域を邪魔してしまう可能性があるため、ラック戻し機構にて検体ラック１９を規定位置まで戻すことが望ましい。 When the sample rack 19 is loaded as it is, the rack returning operation itself in step S108 may be omitted, but the next operation is not the loading of the sample rack 19 from the sample rack loader mechanism 1, but the emergency sample rack. When loading or unloading the sample rack to / from the rack unloader mechanism 2, there is a possibility that the operating area of the rack feeder mechanism 3 may be disturbed, so it is desirable to return the sample rack 19 to the specified position by the rack return mechanism.
　図９は、緊急検体ラックをＳＴＡＴライン（緊急検体ラック投入位置）４７より投入指示したときのラックローダ機構１・ラックアンローダ機構２における動作論理を示したフローチャートである。操作者により緊急検体を保持する検体ラックがＳＴＡＴライン（緊急検体レーン）４７に設置されると、ラック有無センサ１００がＯＮとなり、ステップＳ２０１の緊急検体ラックの投入指示となる。 FIG. 9 is a flowchart showing the operation logic in the rack loader mechanism 1 and the rack unloader mechanism 2 when an emergency sample rack is instructed from the STAT line (emergency sample rack input position) 47. When a sample rack that holds an emergency sample is installed in the STAT line (emergency sample lane) 47 by the operator, the rack presence / absence sensor 100 is turned on, and an instruction to load the emergency sample rack is issued in step S201.
　投入指示が出ると、動作継続中の機構は１ラック分の動作を完了させた後に、緊急検体の搬入動作が割り込んで行われる。つまり、ラック有無検知センサ１００が緊急検体レーン４７に緊急検体ラックが設置されたことを検知すると、分析部５、６、検体ラック搬入搬出機構３、検体容器投入機構１、及び検体容器収納機構２は、動作継続中の１検体ラック１９に保持された検体の処理を完了させた後に、緊急検体の搬入動作が割り込んで行われる。 When the input instruction is issued, the mechanism in operation continues to complete the operation for one rack, and then the emergency sample loading operation is interrupted. That is, when the rack presence / absence detection sensor 100 detects that an emergency sample rack is installed in the emergency sample lane 47, the analyzers 5 and 6, the sample rack loading / unloading mechanism 3, the sample container loading mechanism 1, and the sample container storage mechanism 2 are used. In this case, after completing the processing of the sample held in the one sample rack 19 during the operation, the emergency sample carrying-in operation is interrupted.
　まず、ステップＳ２０２でラックフィーダ機構３のキャリア（検体ラックを移動させる部材）の位置がホームポジションにあるかどうかを確認し、ホームポジション以外にある場合はステップＳ２０３に進み、１ラック分の動作を継続させ、ラックフィーダ機構３のキャリアをホームポジションへ移動する。 First, in step S202, it is confirmed whether or not the position of the carrier (member for moving the sample rack) of the rack feeder mechanism 3 is at the home position. If the position is other than the home position, the process proceeds to step S203 and the operation for one rack is performed. The carrier of the rack feeder mechanism 3 is moved to the home position.
　次に、ステップＳ２０４でアンローダ機構アーム３２の位置を確認し、ホームポジション（検体ラック１９及びアンローダ機構アーム３２が搬入搬出ライン２９上に位置しない図６に示した位置）に無い場合はステップＳ２０５に進み、アンローダ機構アーム３２を搬入搬出ライン２９上に位置しないホームポジションへ移動させ、緊急検体ラックの搬入動作を邪魔しないようにする。 Next, in step S204, the position of the unloader mechanism arm 32 is confirmed. If it is not in the home position (the position shown in FIG. 6 where the sample rack 19 and the unloader mechanism arm 32 are not positioned on the loading / unloading line 29), the process proceeds to step S205. The unloader mechanism arm 32 is moved to a home position that is not located on the loading / unloading line 29 so as not to disturb the loading operation of the emergency sample rack.
　ステップＳ２０４において、アンローダ機構アーム３２がホームポジションに位置する場合は、ステップＳ２０６に進む。そして、ステップＳ２０６において、検体ラックローダ機構１のラックローダ機構アーム２３をホームポジションへ移動し、ラック戻し動作を行える状態にして、ステップＳ２０７におけるラック戻し動作を行う。 In step S204, if the unloader mechanism arm 32 is located at the home position, the process proceeds to step S206. In step S206, the rack loader mechanism arm 23 of the sample rack loader mechanism 1 is moved to the home position so that the rack return operation can be performed, and the rack return operation in step S207 is performed.
　つまり、ラック戻し機構作用点アーム４３により、検体ラック１９を搬入搬出ライン２９から検体ラックトレイ２２に戻し、ラック戻し機構作用点アーム４３が検体ラック１９を検体ラックトレイ２２に戻した方向とは反対の方向に移動し、搬入搬出ライン２９を通過して、緊急検体ラックの搬入動作を阻害しない位置に移動する（図６に示したホームポジション）。 In other words, the sample rack 19 is returned from the loading / unloading line 29 to the sample rack tray 22 by the rack return mechanism operating point arm 43, and is opposite to the direction in which the rack return mechanism operating point arm 43 returns the sample rack 19 to the sample rack tray 22. , Passes through the loading / unloading line 29, and moves to a position that does not hinder the loading operation of the emergency sample rack (home position shown in FIG. 6).
　このラック戻し動作により、検体ラックトレイ２２とフィーダ機構３の境界にきてしまっている検体ラック１９を規定位置に戻し、緊急検体ラックが検体ラックローダ機構１の横を通過する際、緊急検体ラックと検体ラックローダ機構１内の検体ラック１９とが接触する可能性を低減させることができる。 By this rack return operation, the sample rack 19 that has come to the boundary between the sample rack tray 22 and the feeder mechanism 3 is returned to the specified position, and when the emergency sample rack passes by the side of the sample rack loader mechanism 1, And the sample rack 19 in the sample rack loader mechanism 1 can be reduced in contact with each other.
　その後、ステップＳ２０８でフィーダ機構３のキャリアをＳＴＡＴ搬入ポジション４７へ移動させる。そして、ステップＳ２０９で緊急検体ラックをラック待機ディスク４へ搬入し、ラック待機ディスク４内で分析を待っている未処理検体に割り込んで分析装置５又は６へと搬出され、分析が行われる。 Thereafter, the carrier of the feeder mechanism 3 is moved to the STAT carry-in position 47 in step S208. Then, in step S209, the emergency sample rack is carried into the rack standby disk 4, and the unprocessed sample waiting for analysis in the rack standby disk 4 is interrupted and carried out to the analyzer 5 or 6 for analysis.
　ここで、検体への異物混入を防ぐため検体ラックローダ機構１及び検体ラックアンローダ機構２はカバーがされており、ラックトレイの設置・取り出しが少し手間である。
ラックトレイ内のラックを規定位置に戻すことで、ラックトレイベース自体の昇降動作を可能とし、ラックトレイの設置・取り出し時に、ラックトレイベースが上昇して、検体ラックトレイの設置をより簡便なものにしても良い。 Here, the sample rack loader mechanism 1 and the sample rack unloader mechanism 2 are covered in order to prevent foreign matters from being mixed into the sample, and installation and removal of the rack tray is a little troublesome.
By returning the rack in the rack tray to the specified position, the rack tray base itself can be moved up and down, and the rack tray base rises when installing and removing the rack tray, making it easier to install the sample rack tray. Anyway.
　以上のように、本発明の一実施例によれば、分析装置５、６に搬入搬出する検体ラック１９を待機させるラック待機ディスク４に検体ラックを搬入搬出するラックフィーダ機構３の搬入搬出ライン２９の片側に沿って、検体ラックローダ機構１の、検体ラックトレイ１８が設置される投入検体ラックトレイ設置ベース２１と、検体ラックアンローダ機構２の収納検体ラックトレイ設置ベース３４とを配置する。そして、検体ラックローダアーム２３により、検体ラックローダ機構１の設置ベース２２に設置された検体ラックトレイ２２上の検体ラック１９を搬入搬出ライン２９に移動させて、ラック待機ディスク４に検体ラック１９を搬入する。ラック待機ディスク４から搬出された検体ラック１９は、搬入搬出ライン２９により、検体ラックアンローダ機構２の設置ベース３４に設置された検体ラックトレイ３５の近辺まで搬送され、検体ラックアンローダ機構アーム３２により、検体ラックトレイ３５内に移動される。 As described above, according to one embodiment of the present invention, the loading / unloading line 29 of the rack feeder mechanism 3 for loading / unloading the sample racks to / from the rack standby disk 4 for waiting the sample racks 19 loaded / unloaded to / from the analyzers 5 and 6. The sample rack loader mechanism 1 is provided with the input sample rack tray installation base 21 on which the sample rack tray 18 is installed, and the stored sample rack tray installation base 34 of the sample rack unloader mechanism 2 along one side. Then, the sample rack loader arm 23 moves the sample rack 19 on the sample rack tray 22 installed on the installation base 22 of the sample rack loader mechanism 1 to the loading / unloading line 29, and the sample rack 19 is placed on the rack standby disk 4. Carry in. The sample rack 19 unloaded from the rack standby disk 4 is transported to the vicinity of the sample rack tray 35 installed on the installation base 34 of the sample rack unloader mechanism 2 by the loading / unloading line 29, and by the sample rack unloader mechanism arm 32. The sample is moved into the sample rack tray 35.
　このようにして、検体ラックトレイ３５内に検体ラックトレイ１８が移動されるので、別箇にバッファ部を設けることなく、検体ラック１９を外部に取り出すことができる。 Since the sample rack tray 18 is moved into the sample rack tray 35 in this way, the sample rack 19 can be taken out without providing a separate buffer unit.
　検体ラックローダ機構１では、検体ラック１９の外部への搬出時には、ラックローダアーム２３を初期位置にまで移動して、検体ラックトレイ２２に検体ラック１９を追加可能なようにスペースを形成し、かつ、ラック戻し機構作用点アーム４３により、検体ラック１９を検体ラック待機位置４６まで押し戻すことにより、検体ラック１９を搬入搬出ライン２９上から確実に退避することができ、別箇にバッファ部を設けることなく、検体ラックトレイ２２を搬出することができる。 The sample rack loader mechanism 1 moves the rack loader arm 23 to the initial position when carrying out the sample rack 19 to the outside, forms a space so that the sample rack 19 can be added to the sample rack tray 22, and By pushing the sample rack 19 back to the sample rack standby position 46 by the rack return mechanism action point arm 43, the sample rack 19 can be reliably retracted from the loading / unloading line 29, and a separate buffer unit is provided. The sample rack tray 22 can be carried out.
　すなわち、本発明によれば、別箇のバッファ機構を備えることなく、検体ラックトレイから直接検体ラックを取り出すことが可能であり、かつ、検体ラックトレイに検体ラックが残っている場合でも、検体ラックトレイを外部に搬出し、追加の検体ラック投入を可能とする自動分析装置を実現することができる。 That is, according to the present invention, the sample rack can be taken out directly from the sample rack tray without providing a separate buffer mechanism, and even if the sample rack remains in the sample rack tray, the sample rack can be removed. It is possible to realize an automatic analyzer that can carry out the tray to the outside and insert an additional sample rack.
　なお、上述した例では、搬入搬出ライン２９の片側に沿って、投入検体ラックトレイ設置ベース２１と、収納検体ラックトレイ設置ベース３４とを配置する構成としたが、搬入搬出ライン２９の両側に搬入搬出ライン２９に沿って、投入検体ラックトレイ設置ベース２１と、収納検体ラックトレイ設置ベース３４とを配置する構成とすることも可能である。 In the above-described example, the input sample rack tray installation base 21 and the storage sample rack tray installation base 34 are arranged along one side of the carry-in / out line 29. A configuration in which the input sample rack tray installation base 21 and the storage sample rack tray installation base 34 are disposed along the carry-out line 29 is also possible.
　また、検体ラックローダ機構アーム２３、検体ラックアンローダ機構アーム３２、ラック戻し機構力点アーム４１、及びラック戻し機構作用点アーム４３の材質は、強固なものであれば種類は問わないが、金属製であることが望ましい。 The material of the sample rack loader mechanism arm 23, the sample rack unloader mechanism arm 32, the rack return mechanism force point arm 41, and the rack return mechanism action point arm 43 is not limited as long as it is strong, but is made of metal. It is desirable to be.
　また、投入検体ラックトレイ設置ベース２１及び収納検体ラックトレイ設置ベース３４を、自動分析装置から着脱可能に構成することもできる。 Also, the input sample rack tray installation base 21 and the storage sample rack tray installation base 34 can be configured to be detachable from the automatic analyzer.
　１・・・検体容器投入機構（検体ラックローダ機構）、　２・・・検体容器収納機構（検体ラックアンローダ機構）、　３・・・ラックフィーダ機構、　４・・・ラック待機ディスク、　５・・・生化学分析装置、　６・・・免疫分析装置、　７・・・サンプリングライン、　１０・・・試薬保冷庫、　１２・・・反応部、　１３・・・サンプリングライン、　１４・・・検体サンプリング機構、　１５・・・マイクロコンピュータ（動作制御部）、　１６・・・表示部、　１７・・・試薬保冷庫、　１８・・・検体ラックトレイ、　１９・・・検体ラック、　２０・・・検体ラック転倒防止溝、　２１・・・投入検体ラックトレイ設置ベース、　２２・・・投入検体ラックトレイ、　２３・・・検体ラックローダ機構アーム、　２５・・・検体ラック有無検知センサ、　２６・・・フィーダラインへのラック到達位置、　２７・・・検体・検体ラックバーコードリーダ、　２９・・・検体ラックフィーダ機構搬入搬出ライン、　３１・・・検体ラックフィーダ機構搬出口到達ポジション、　３２・・・検体ラックアンローダ機構アーム、　３４・・・収納検体ラックトレイ設置ベース、　３５・・・収納検体ラックトレイ、　３６・・・収納済み検体ラック、　３７・・・収納検体ラック満杯センサ、　３８・・・投入待ち検体ラック待機位置、　４０・・・検体ラックローダ機構アーム待機位置（ホームポジション）、　４１・・・ラック戻し機構力点アーム、　４２・・・ラック戻し機構支点、　４３・・・ラック戻し機構作用点アーム、　４６・・・検体ラック戻し動作後の投入待ち検体ラック待機位置、　４７・・・緊急検体ラック投入位置（ＳＴＡＴライン）、　５０・・・アンローダアーム移動機構、　５１・・・ローダアーム移動機構、　６０・・・検体容器、　１００・・・緊急検体ラック有無検知センサ、　３００、３０１・・・ラックトレイ有無センサ DESCRIPTION OF SYMBOLS 1 ... Sample container loading mechanism (sample rack loader mechanism), 2 ... Sample container storage mechanism (sample rack unloader mechanism), 3 ... Rack feeder mechanism, 4 ... Rack standby disk, 5 ... Biochemical analyzer, 6 ... Immunoanalyzer, 7 ... Sampling line, 10 ... Reagent cooler, 12 ... Reaction unit, 13 ... Sampling line, 14 ... Sample sampling mechanism, 15 ... Microcomputer (operation control unit), 16 ... Display unit, 17 ... Reagent cooler, 18 ... Sample rack tray, 19 ... Sample rack, 20 ... Sample rack fall prevention Groove, 21 ... Input sample rack tray installation base, 22 ... Input sample rack tray, 23 ... Sample rack loader mechanism arm, 25 ... Sample rack presence / absence detection sensor, 26 ... Rack arrival position to feeder line, 27 ... Sample / sample rack barcode reader, 29 ... Sample rack feeder mechanism loading / unloading line, 31 ... Sample rack feeder mechanism Unloading arrival position, 32 ... Sample rack unloader mechanism arm, 34 ... Stored sample rack tray installation base, 35 ... Stored sample rack tray, 36 ... Stored sample rack, 37 ... Stored sample Rack full sensor, 38 ... Sample rack standby position waiting to be loaded, 40 ... Sample rack loader mechanism arm standby position (home position), 41 ... Rack return mechanism force point arm, 42 ... Rack return mechanism fulcrum, 43 ... Rack return mechanism action point arm, 46 ... Sample rack return operation Specimen rack waiting position for loading, 47 ... Emergency specimen rack loading position (STAT line), 50 ... Unloader arm moving mechanism, 51 ... Loader arm moving mechanism, 60 ... Sample container, 100 ...・ Emergency sample rack presence / absence detection sensor, 300, 301 ... rack tray presence / absence sensor

Claims (8)

  1. 　検体を分析する分析部と、
    　上記分析部に検体容器を保持する検体ラックを搬入し、上記分析部から上記検体容器を搬出する搬入搬出ラインを有する検体ラック搬入搬出機構と、
    　上記検体ラックを架設する検体ラックトレイを着脱可能に設置し、上記検体ラックを上記検体ラック搬入搬出機構の上記搬入搬出ラインに投入する検体容器投入機構と、
    　上記検体ラックトレイを着脱可能に設置し、上記搬入搬出ラインから上記検体ラック回収し収納する検体容器収納機構と、
    　上記分析部、上記検体ラック搬入搬出機構、上記検体容器投入機構、及び検体容器収納機構の動作を制御する動作制御部と、
    　を備えることを特徴とする自動分析装置。     An analysis unit for analyzing a sample;
    A sample rack carrying a sample rack for holding a sample container into the analysis unit, and a sample rack loading / unloading mechanism having a loading / unloading line for unloading the sample container from the analysis unit;
    A sample container loading mechanism for detachably installing a sample rack tray for laying the sample rack, and loading the sample rack into the loading / unloading line of the sample rack loading / unloading mechanism;
    A sample container storage mechanism that detachably installs the sample rack tray and collects and stores the sample rack from the loading / unloading line;
    An operation control unit for controlling operations of the analysis unit, the sample rack loading / unloading mechanism, the sample container loading mechanism, and the sample container storage mechanism;
    An automatic analyzer characterized by comprising.
  2. 　請求項１に記載の自動分析装置において、
    　上記検体容器投入機構は、上記検体ラックトレイ上の上記検体ラックを上記搬入搬出ラインに送り出すラック送り出し動作方向と、このラック送り出し動作方向と反対方向であるリセット動作方向に移動するローダ機構アームを有し、
    　上記検体容器収納機構は、上記検体ラックを上記搬入搬出ラインから上記検体ラックトレイ上に移動する動作方向と、この動作方向と反対方向の動作方向に移動するアンローダ機構アームを有することを特徴とする自動分析装置。     The automatic analyzer according to claim 1,
    The sample container loading mechanism has a loader mechanism arm that moves in a rack feeding operation direction for feeding the sample rack on the sample rack tray to the loading / unloading line and a reset operation direction opposite to the rack feeding operation direction. And
    The sample container storage mechanism includes an operation direction in which the sample rack is moved from the loading / unloading line onto the sample rack tray, and an unloader mechanism arm that is moved in an operation direction opposite to the operation direction. Automatic analyzer.
  3. 　請求項２に記載の自動分析装置において、
    　上記検体容器投入機構は、上記検体ラックを、上記搬入搬出ラインから離れる方向へ移動するラック戻しアームを有することを特徴とする自動分析装置。     The automatic analyzer according to claim 2,
    The automatic analyzer according to claim 1, wherein the sample container loading mechanism includes a rack return arm that moves the sample rack in a direction away from the loading / unloading line.
  4. 　請求項３に記載の自動分析装置において、
    　上記検体ラック搬入搬出機構は、緊急検体レーンと、この緊急検体レーンに緊急検体を収容した検体容器を保持する緊急検体ラックが設置されたことを検知するラック有無検知センサとを有し、このラック有無検知センサが上記緊急検体レーンに緊急検体ラックが設置されたことを検知すると、上記アンローダ機構アームは上記搬入搬出ライン上から移動し、上記ラック戻しアームは、上記検体ラックを上記搬入搬出ラインから上記検体ラックトレイに戻し、上記検体ラックを上記検体トレイに戻した方向とは反対の方向に移動し、上記搬入搬出ラインを通過して、上記緊急検体ラックの搬入動作を阻害しない位置に移動することを特徴とする自動分析装置。     The automatic analyzer according to claim 3,
    The sample rack loading / unloading mechanism includes an emergency sample lane and a rack presence / absence detection sensor that detects that an emergency sample rack that holds a sample container containing an emergency sample is installed in the emergency sample lane. When the presence / absence detection sensor detects that an emergency sample rack is installed in the emergency sample lane, the unloader mechanism arm moves from the loading / unloading line, and the rack return arm moves the sample rack from the loading / unloading line. Return to the sample rack tray, move in the direction opposite to the direction in which the sample rack is returned to the sample tray, pass through the loading / unloading line, and move to a position that does not hinder the loading operation of the emergency sample rack. An automatic analyzer characterized by that.
  5. 　請求項４に記載の自動分析装置において、
    　上記ラック有無検知センサが上記緊急検体レーンに上記緊急検体ラックが設置されたことを検知すると、上記分析部、上記検体ラック搬入搬出機構、上記検体容器投入機構、及び検体容器収納機構は、動作継続中の一つの上記検体ラックに保持された検体の処理を完了させた後に、上記緊急検体ラックの搬入動作を開始することを特徴とする自動分析装置。     The automatic analyzer according to claim 4,
    When the rack presence / absence detection sensor detects that the emergency sample rack is installed in the emergency sample lane, the analysis unit, the sample rack loading / unloading mechanism, the sample container loading mechanism, and the sample container storage mechanism continue to operate. An automatic analyzer which starts the loading operation of the emergency sample rack after the processing of the sample held in one of the sample racks is completed.
  6. 　請求項３に記載の自動分析装置において、
    　上記検体容器投入機構は、上記検体ラックが上記搬入搬出ラインに位置することを検知する検体ラック有無検知センサを有し、上記検体ラックトレイが上記検体容器投入機構から取り出された後、再度、上記検体容器投入機構に設置されると、上記ローダ機構アームは上記ラック送り出し方向に移動し、上記検体ラック有無検知センサが、上記検体ラックが上記搬入搬出ラインに位置することを検知すると、上記ラック戻しアームは、上記搬入搬出ラインに位置する検体ラックを、上記検体ラックトレイ上に戻すことを特徴とする自動分析装置。     The automatic analyzer according to claim 3,
    The sample container loading mechanism includes a sample rack presence / absence detection sensor that detects that the sample rack is positioned on the loading / unloading line, and after the sample rack tray is removed from the sample container loading mechanism, When installed in the sample container loading mechanism, the loader mechanism arm moves in the rack feed-out direction, and when the sample rack presence / absence detection sensor detects that the sample rack is located on the loading / unloading line, the rack return arm is moved. The automatic analyzer according to claim 1, wherein the arm returns the sample rack positioned on the loading / unloading line onto the sample rack tray.
  7. 　請求項６に記載の自動分析装置において、
    　上記動作制御部は、上記検体ラックトレイが、再度、上記検体容器投入機構に設置され、上記ローダ機構アームが上記ラック送り出し方向に移動した送り量を算出し、算出した送り量から投入された検体ラックの数を算出することを特徴とする自動分析装置。     The automatic analyzer according to claim 6,
    The operation control unit calculates a feed amount in which the sample rack tray is again installed in the sample container loading mechanism, the loader mechanism arm moves in the rack feed direction, and a sample loaded from the calculated feed amount An automatic analyzer characterized by calculating the number of racks.
  8. 　請求項１乃至７のうちのいずれか一項に記載の自動分析装置において、
    　上記検体容器投入機構及び上記検体容器収納機構のそれぞれは、上記自動分析装置に着脱可能な検体ラックトレイ設置ベースを有し、これら検体ラックトレイ設置ベースのそれぞれに、上記検体ラックトレイが設置されることを特徴とする自動分析装置。     In the automatic analyzer as described in any one of Claims 1 thru | or 7,
    Each of the sample container loading mechanism and the sample container storage mechanism has a sample rack tray installation base that can be attached to and detached from the automatic analyzer, and the sample rack tray is installed on each of the sample rack tray installation bases. An automatic analyzer characterized by that.
PCT/JP2018/018905 2017-06-02 2018-05-16 Automatic analysis device WO2018221220A1 (en)

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