WO2018199540A1 - Transparent solubilized cosmetic composition and preparation method therefor - Google Patents

Abstract

The present invention relates to a transparent solubilized cosmetic composition containing an odorant of a surfactant-free system, and a preparation method therefor. According to the present invention, a transparent solubilized cosmetic composition having excellent transparency and aging stability, being safe for the skin, and having a high refreshing sensation and freshness can be provided.

Description

Transparent solubilizing cosmetic composition and preparation method thereof

The present invention relates to a transparent solubilizing cosmetic composition comprising a fragrance of a surfactant-free system and a method for producing the same.

The transparent solubilized cosmetic composition provides a refreshing feeling with a refreshing effect. The transparent solubilizing cosmetic composition is generally prepared in a transparent or translucent formulation. Because of this formulation characteristic, the transparent solubilized cosmetic composition cannot contain oily components except for a very small amount of oil components such as insoluble or poorly soluble fragrances in water. That is, in order to inject an oily component into a transparent solubilized cosmetic composition prepared in a transparent or translucent formulation, the use of a surfactant that is a solubilizer for solubilizing it is inevitable. However, the use of such surfactants may sometimes cause a sticky feeling or cause skin irritation.

Accordingly, the present applicant focuses on the above-mentioned problem, transparent solubilizing cosmetic composition and its preparation capable of transparently solubilizing insoluble or poorly soluble oily components in water, such as perfume, without using a surfactant, and can maintain a stable dispersion system for a long time. The present invention has been completed to provide a method.

It is an object of the present invention to provide a transparent solubilizing cosmetic composition of a surfactant-free system comprising a fragrance which is an oily component and a method for producing the same.

In order to achieve the above object, the present invention provides a transparent solubilizing cosmetic composition comprising a perfume, a diol-based compound and water, wherein the diol-based compound is characterized in that the RHLB is 10 or more, the molecular weight is 90 to 300. .

In addition, the present invention provides a method for preparing a transparent solubilized cosmetic composition through the aging process after dispersing by mixing the perfume, diol-based compound and water.

Method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention comprises the steps of preparing a suspension solution by mixing a fragrance, a diol-based compound and water; And aging the suspension solution. In this case, the diol-based compound may be RHLB is 10 or more, the molecular weight of 90 to 300. In addition, the suspension solution by satisfying the following formula 2 by the aging, thereby providing a transparent solubilized cosmetic composition.

[Relationship 2]

0.001 ≤ T ₁ / T ₀ ≤ 0.5

[In relation 2,

T ₀ is the turbidity of the suspension solution;

T ₁ is the turbidity of the aged composition]

In the method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention, the suspension solution may include 1 to 20 parts by weight of a diol compound based on 1 part by weight of the perfume.

In the method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention, the suspension solution may further comprise 1 to 30 parts by weight of ethanol based on 1 part by weight of the perfume.

In the method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention, the aging may be natural aging left at room temperature or artificial aging to promote molecular motion by applying external energy.

According to the present invention, despite being a surfactant-free system, it is possible to maintain a stable dispersion system of perfume as an oily component in a transparent solubilized formulation.

In addition, according to the present invention to achieve a dynamic equilibrium within a short time through the step of aging the suspension solution containing the fragrance and the predetermined diol-based compound as an oily component, it is possible to maintain the transparency of the formulation for a long time.

In addition, according to the present invention can effectively mask off-odor of ethanol used to give a refreshing feeling and fresh feeling, and maximize the feeling of use of the transparent solubilized cosmetic composition.

In short, according to the present invention, it is possible to transparently solubilize oil-based components such as perfumes without containing a surfactant, have excellent transparency and stability over time, and do not use a surfactant that had to be used to solubilize oil-based components in the past. This can prevent problems caused by this. That is, according to the present invention can provide a transparent solubilized cosmetic composition that satisfies the safety of the skin and the stability of the formulation at the same time.

1 is a graph showing the change in turbidity change of the cosmetic composition prepared by the method of the Examples and Comparative Examples according to the present invention.

The transparent solubilized cosmetic composition according to the present invention and a method for preparing the same are described below. However, unless otherwise defined in the technical and scientific terms used at this time, those skilled in the art generally understand In the following description, descriptions of well-known functions and configurations that may unnecessarily obscure the subject matter of the present invention will be omitted.

As used herein, the term "required hydrophilic-lipophilic balance (RHLB)" means a relative value of hydrophilicity and hydrophobicity suitable for forming a stable dispersion system of each raw material, and HLB (Hydrophilic) of a general surfactant. Lipophilic Balance (ratio of hydrophilicity and hydrophobicity). The RHLB may also be represented by a value of 0 to 20, and a low value thereof may indicate a lipophilic characteristic, and a high value thereof may indicate a hydrophilic characteristic.

The term "dispersion system" in the present invention means a system in which another liquid is dispersed in a small particle state in a liquid of a Han group in two mixed liquids which are not mixed with each other. Such dispersion systems can be divided into emulsion, solubilization, microemulsion, and the like depending on particle size and thermodynamic stability.

As used herein, the term "solubilization" refers to a stable dispersion system that has reached thermodynamic equilibrium. In addition, the term "suspension" in the present invention may be a microemulsion state having a particle size of several hundred nanometers to several tens of micrometers, and refers to a thermodynamic labile dispersion system.

The term "turbidity" in the present invention, means for evaluating the transparency of the transparent solubilized cosmetic composition according to the present invention, using a nephelometer turbidimeter (HANNA HI 98703 Turbidimeter, HANNA Instruments), at room temperature (20 ℃) It is measured and quantified in Népelometer turbidity units (NTU). At this time, distilled water (NTU = 0) was used as a standard, and the average value of the numerical value measured by sampling the same sample 4 times was used.

In addition, in the present invention, all relations to turbidity were quantified as relative nephelometry unit (RNU) relative to turbidity. In one embodiment, the relationship 1 is a numerical value representing the stability of the transparent solubilized cosmetic composition according to the present invention was calculated based on the following formula 1, the unit has a relative non-turbidity unit as described above.

[Equation 1]

T _S = T ₂ / T ₁

[In Formula 1,

T ₁ is the initial haze of the transparent solubilizing composition according to the present invention;

T ₂ is the turbidity of the transparent solubilizing composition after 4 weeks under 20 ° C. conditions;

T _S is a relative value of turbidity (T ₂ ) after 4 weeks to initial turbidity (T ₁ ), and the relative value has a relative non-turbidity unit compared to the initial turbidity]

As used herein, the term "alkylene" refers to an organic radical derived by the removal of one hydrogen from linear or pulverized alkyl having 1 to 7 carbon atoms, "* -C (R ^a ) (R ^b )-*" It may be represented as. In this case, when R ^a and R ^b are hydrogen at the same time, it means an unsubstituted alkylene, one or two selected from R ^a and R ^b are each independently C ₁ ~ C ₇ alkyl, C ₁ ~ C ₇ When selected from alkoxy and C ₁ to C ₇ thioxy and the like, it means substituted alkylene.

Applicant has repeated studies on transparent solubilized cosmetic compositions containing oil-insoluble or poorly soluble oily components in water, such as perfumes, in a surfactant-free system, and identified a predetermined diol-based compound showing affinity with perfumes. It was confirmed that the desired transparent solubilized formulation can be prepared.

Specifically, the diol-based compound has amphipathic, mixed with the fragrance to form a dispersion system of several hundred nanometers to several tens of micrometers, and then through the aging step to implement a transparent solubilized formulation that quickly reached dynamic equilibrium. That is, according to the present invention, a thermodynamically stable transparent solubilized formulation can be provided in a simple process without using a surfactant.

Transparent solubilizing cosmetic composition according to an aspect of the present invention comprises a perfume, a diol-based compound and water, the diol-based compound is characterized by satisfying the following conditions.

10 ≤ Required Hydrophilic Lipophilic Balance (RHLB)

90 ≤ molecular weight (Mw) ≤ 300

In general, the transparent solubilized cosmetic composition must use a high hydrophilic surfactant, that is, a hydrophilic surfactant in order to use an oily component. As an example of the hydrophilic surfactant most used for a transparent solubilizing cosmetic composition, synthetic surfactant etc. which added polyoxyethylene or polyglycerol, etc. are mentioned. Although these oils can stably solubilize oily ingredients such as fragrances, they give a feeling of stickiness when used on the skin, and not only impair the freshness or freshness peculiar to the transparent solubilized cosmetic composition, but the use of such synthetic surfactants is not only safe for human safety and environmental toxicity. It is possible to cause the use thereof is undesirable.

Although the transparent solubilized cosmetic composition according to an aspect of the present invention does not use the synthetic surfactant described above, it is noted in terms of achieving a turbidity (transparency) equivalent to or higher than that of using the synthetic surfactant.

In one embodiment, the transparent solubilized cosmetic composition according to an aspect of the present invention may be a dynamic equilibrium after mixing the fragrance and the diol-based compound in a 1: 1 to 1: 20 weight ratio. In this case, the transparent solubilized cosmetic composition may be mixed in a weight ratio of 1: 1 to 1:15, more preferably 1: 1 to 1:10, for stable dispersion of the initial dispersion system (suspension).

The diol-based compound of the transparent solubilizing cosmetic composition according to an embodiment of the present invention may be represented by the following formula (1).

[Formula 1]

[In Formula 1,

R ₁ and R ₂ are each independently hydrogen or hydroxy, and R ₁ and R ₂ are different from each other;

Y is substituted or unsubstituted C ₁ -C ₇ alkylene;

n is 0 or 1]

In one embodiment, the diol compound is 1,5-pentanediol (1,5-pentanediol), 1,6-hexanediol (1,6-hexanediol), 1,2-pentanediol (1,2-pentanediol ), 1,2-hexanediol (1,2-hexanediol), 1,2-octanediol (1,2-octanediol) and ethylhexylglycerin (Ethylhexylglycerin) and the like, the diol-based compound alone or two or more It can of course be used as a mixed mixture.

In particular, the diol-based compound is a single or two or more selected from 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, ethylhexylglycerine and the like in view of showing a similar behavior to the hydrophilic surfactant It can be used as a mixed mixture and is prioritized in the present invention.

The transparent solubilized cosmetic composition according to an aspect of the present invention is characterized by having a turbidity of 30 NTU or less. In this case, in the present invention, the turbidity of 30 NTU or less is considered to be visually transparent, and the turbidity value of 30 NTU means the maximum turbidity value that is determined to be visually transparent.

In one embodiment, the transparent solubilized cosmetic composition that satisfies the turbidity described above may have an emulsion particle size of 100 nm or less. At this time, in terms of satisfying a stable solubilizing dispersion system with excellent transparency at the same time, preferably may have an emulsion particle size of 1 to 50 nm, more preferably 10 to 30 nm, but is not limited thereto.

In one embodiment, the stability of the transparent solubilized cosmetic composition according to an aspect of the present invention may be to satisfy the following relationship 1.

[Relationship 1]

0.90 ≤ T _S ≤ 1.10

[In relation 1,

T _S means the relative value of the turbidity (T ₂ ) of the composition after 4 weeks at 20 ° C. compared to the turbidity (T ₁ ) of the initial composition.]

The closer the T _S value is to 1.00, the lower the change rate of turbidity of the initial composition, and when the value is greater than 1.00, it means that the transparency of the turbidity of the initial composition is poor.

In one embodiment, the stability (T _S ) of the transparent solubilized cosmetic composition according to an aspect of the present invention may preferably range from 0.92 to 1.08, more preferably 0.94 to 1.06, but is not limited thereto.

The transparent solubilized cosmetic composition according to an aspect of the present invention may further include 1 to 30 parts by weight of ethanol, based on 1 part by weight of the fragrance, in order to implement more improved turbidity. Ethanol in the present invention may be used not only for the synergistic effect of the above-described effect, but also for a refreshing and fresh feeling, which is the basic feeling of the transparent solubilized cosmetic composition.

However, the ethanol does not exceed at most 10% by weight based on the total weight of the composition. The use of ethanol exceeding the above range may help to solubilize the fragrance of the oil component by increasing the distribution coefficient of the fragrance of the oil component, but the masking of the ethanol specific odor by the fragrance may not be expected. It is not preferable because it can cause irritation.

In another aspect, the present invention provides a method for producing a transparent solubilizing cosmetic composition of a surfactant that can solubilize the fragrance which is an oil-based component without a surfactant.

Method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention comprises the steps of preparing a suspension solution by mixing a fragrance, a diol-based compound and water; And aging the suspension solution. In this case, the diol-based compound may be RHLB is 10 or more, the molecular weight of 90 to 300.

The method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention provides the transparent solubilized cosmetic composition by satisfying the following Formula 2 by the aging.

[Relationship 2]

0.001 ≤ T ₁ / T ₀ ≤ 0.5

[In relation 2,

T ₀ is the turbidity of the suspension solution;

T ₁ is the turbidity of the aged composition]

In one embodiment, the transparent solubilized cosmetic composition according to an aspect of the present invention has a relative value (T ₁ / T ₀ ) of turbidity relative to the suspension solution by aging is preferably in the range of 0.001 to 0.1, more preferably in the range of 0.01 to 0.1 It may be, but is not limited thereto.

In one embodiment, in the method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention, the perfume and the diol compound may be mixed in a weight ratio of 1: 1 to 1:20. At this time, the transparent solubilized cosmetic composition may be mixed in an initial dispersion system, that is, a weight ratio of preferably 1: 1 to 1:15, more preferably 1: 1 to 1:10 by weight for stable dispersion of the suspension solution, but is not limited thereto. It doesn't work.

In one embodiment, in the method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention, in order to increase the distribution coefficient of the fragrance which is an oil component, ethanol may be further included. In this case, the ethanol is not limited if the amount used is 10 wt% or less based on the total weight of the composition, but preferably 1 to 30 parts by weight based on 1 part by weight of the perfume.

In the method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention, the aging may be natural aging or artificial aging to promote molecular movement by applying external energy. In this case, the external energy may be used without limitation as long as it can promote molecular motion such as heat, vibration, and ultrasonic waves.

In one embodiment, the natural ripening may be left for 4 to 48 hours at 20 to 30 ℃.

In one embodiment, the artificial ripening by heat may be performed for 4 to 48 hours in a temperature range of more than 30 ℃ or under stirring. At this time, the speed of the stirring is not limited, but may be a low speed stirring of 50 to 100 rpm.

In one embodiment, the artificial ripening due to the vibration may be processed for 1 minute to 5 minutes at an intensity of 80 to 200dB using a sound wave of a frequency of 0.5 to 2kHz.

In one embodiment, the artificial aging by the ultrasonic wave may be treated for 1 minute to 5 minutes at 0.1 to 100 mW / ㎠ using ultrasonic waves of a frequency of 10 to 2000kHz.

Method for producing a transparent solubilized cosmetic composition according to an aspect of the present invention by using the suspension solution of the above-described combination of natural aging using natural molecular motion or external energy for promoting molecular motion by heat, vibration, ultrasonic waves, etc. Through artificial aging utilized, it is possible to provide a transparent solubilized formulation in a short time. This can be evaluated as a remarkable technique in that the transparent solubilized formulation including the fragrance as an oily component has a stable dispersion system in a surfactant-free system.

In particular, the transparent solubilized cosmetic composition according to an aspect of the present invention, in terms of excellent transparency as well as can maintain transparency in the long-term storage stability from low to high temperature, the transparent solubilized cosmetic composition solubilizing the fragrance with a surfactant-free system To have a technological advantage.

Hereinafter, the transparent solubilized cosmetic composition and its preparation method according to an embodiment of the present invention will be described in more detail with reference to Examples. However, the following examples are only one reference for describing the present invention in detail, and the present invention is not limited thereto and may be implemented in various forms. In addition, the units of the component not specifically described in the specification may be g or weight% based on the total composition.

Turbidity Evaluation Method

In order to evaluate the transparency of the transparent solubilized cosmetic composition prepared in the following Examples and Comparative Examples, it was measured at 20 ° C using a nephelometer turbidimeter (HANNA HI 98703 Turbidimeter, HANNA Instruments). At this time, the turbidity was measured in Nephelometer turbidity unit (NTU), distilled water (NTU = 0) was used as a standard.

A dram screw cap vial (70 mm × 25 mm) was filled with the transparent solubilizing cosmetic composition prepared in each example or comparative example to nearly normal and centrifuged at 100 rpm until all bubbles were removed. In centrifugation, each vial was wiped with tissue paper to remove any stains before entering the turbidimeter. Each vial was placed in a turbidimeter and reading was performed. When the reading stabilized, it was recorded as the NTU value. Each vial was turned by a quarter to make another reading and recording. This was repeated until four readings were performed. The mean value of the four readings was recorded as the turbidity value, ie each T ₁ value.

In addition, the turbidity value of the suspension solution before aging was measured by the same method, and the turbidity value thereof was recorded as each T ₀ value.

In addition, the turbidity value of the transparent solubilized cosmetic composition prepared in each Example or Comparative Example in which the T ₁ value was measured by the above method was measured for 4 weeks under 20 ° C constant temperature condition, and its turbidity value was measured. Each T ₂ value was recorded.

In this case, the stability (T _S ) of the transparent solubilized cosmetic composition prepared in each Example or Comparative Example is a value calculated from the following Equation 1.

[Equation 1]

T _S = T ₂ / T ₁

[In Formula 1,

T ₁ is the initial haze of the transparent solubilizing composition according to the present invention;

T ₂ is the turbidity of the transparent solubilizing composition after 4 weeks under 20 ° C. conditions;

T _S is a relative value of turbidity (T ₂ ) after 4 weeks to initial turbidity (T ₁ ), and the relative value has a relative non-turbidity unit compared to the initial turbidity]

(Examples 1 to 6)

To prepare a suspension solution by stirring at 300rpm for 10 minutes at room temperature (20 ℃) in the composition of Table 1. Each suspension solution was left to stand at room temperature for 48 hours to mature naturally, thereby preparing a transparent solubilized cosmetic composition.

At this time, the turbidity of the suspension solution and the transparent solubilized cosmetic composition after aging was measured by the turbidity evaluation method described above, the results are shown in Table 2 below.

(Example 7)

To prepare a suspension solution by stirring at 300rpm for 10 minutes at room temperature (20 ℃) in the same composition as in Example 6 of Table 1. Each suspension solution was left at 50 ° C. for 24 hours to artificially mature to prepare a transparent solubilized cosmetic composition.

At this time, the turbidity of the suspension solution and the transparent solubilized cosmetic composition after aging was measured by the turbidity evaluation method described above, the results are shown in Table 2 below.

(Comparative Examples 1 to 5)

To prepare a suspension solution by stirring at 300rpm for 10 minutes at room temperature (20 ℃) in the composition of Table 1. Each suspension solution was left at room temperature for 48 hours to mature naturally to prepare a cosmetic composition.

At this time, the turbidity of the suspension solution and the cosmetic composition after aging was measured by the turbidity evaluation method described above, and the results are shown in Table 2 below.

As shown in Table 2 above, the transparent solubilized cosmetic composition according to the present invention was a suspension solution having a turbidity value of 200 or more NTU immediately after mixing the respective components, but was transparent solubilization having a turbidity value of 30 NTU or less through the aging process. It was confirmed that the formulation can be implemented. In this case, in the transparent solubilized cosmetic composition according to the present invention, it was confirmed that Examples 2 to 6 can implement a better turbidity (transparency) than Example 1. The implementation of this effect is expected because 1,2-hexanediol, 1,2-octanediol and ethylhexylglycerine exhibit the same behavior as hydrophilic surfactants due to their structural characteristics.

In addition, it was confirmed that the transparent solubilized cosmetic composition according to the present invention can ensure the thermodynamic stability and maintain transparency even after long-term storage. In Table 2, only stability under 20 ° C is described, but in addition to constant temperature conditions of -20 ° C, 4 ° C, 35 ° C, and 45 ° C, storage for 3 months under cycle conditions of 0 ° C to 40 ° C (1 cycle based on 12 hours) The results also confirmed that the initial transparency was not lost.

In addition, the transparent solubilized cosmetic composition according to the present invention, despite the use of up to 10% by weight of ethanol, it was confirmed that can effectively mask the ethanol-specific odor with solubilized flavoring.

In addition, as shown in Table 2, Comparative Example 1 was able to prepare a transparent solubilized cosmetic composition using a synthetic surfactant, but when used on the skin provided a feeling of stickiness rather than a refreshing and fresh feeling, Comparative Example 2 , 4 and 5 performed the aging process under the same conditions, but did not improve the transparency, remained suspended or the perfume was separated and suspended on the surface. In addition, Comparative Example 3 using ethanol corresponding to 15% by weight based on the total weight of the composition was not able to mask the odor peculiar to ethanol, as well as causing strong irritation to the skin was confirmed that it is not preferable.

In the present invention as described above has been described by specific embodiments and limited embodiments and drawings, but this is only provided to help a more general understanding of the present invention, the present invention is not limited to the above embodiments, the present invention Those skilled in the art can make various modifications and variations from this description.

Therefore, the spirit of the present invention should not be limited to the described embodiments, and all the things that are equivalent to or equivalent to the claims as well as the following claims will belong to the scope of the present invention. .

Claims (11)

1. A fragrance-soluble cosmetic composition comprising a fragrance, a diol-based compound and water, wherein the diol-based compound satisfies the following conditions.

   10 ≤ required hydrophilic-lipophilic balance (RHLB)

   90 ≤ molecular weight (Mw) ≤ 300
2. The method of claim 1,

   On the basis of 1 part by weight of the perfume, a transparent solubilizing cosmetic composition comprising 1 to 20 parts by weight of a diol-based compound.
3. The method of claim 1,

   The diol-based compound is a transparent solubilized cosmetic composition is represented by the following formula (1).

   [Formula 1]

   

   [In Formula 1,

   R ₁ and R ₂ are each independently hydrogen or hydroxy, and R ₁ and R ₂ are different from each other;

   Y is substituted or unsubstituted C ₁ -C ₇ alkylene;

   n is 0 or 1]
4. The method of claim 3, wherein

   The diol compound is at least one transparent solubilization selected from 1,5-pentanediol, 1,6-hexanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol and ethylhexylglycerine Cosmetic composition.
5. The method of claim 1,

   Turbidity of the composition is a transparent solubilizing cosmetic composition of 30 NTU or less.
6. The method of claim 5,

   The stability of the composition is a transparent solubilized cosmetic composition that satisfies the following relation 1.

   [Relationship 1]

   0.90 ≤ T _S ≤ 1.10

   [In relation 1,

   T _S means the relative value of the turbidity of the composition after 4 weeks under 20 ° C. compared to the turbidity (T ₁ ) of the initial composition]
7. The method of claim 1,

   On the basis of 1 part by weight of the fragrance, the transparent solubilized cosmetic composition further comprises 1 to 30 parts by weight of ethanol.
8. Preparing a suspension solution by mixing a flavoring agent, a diol compound, and water; And aging the suspension solution; wherein the diol-based compound has a required hydrophilic-lipophilic group balance of 10 or more, a molecular weight of 90 to 300, and satisfies the following Equation 2 by the aging. How to prepare.

   [Relationship 2]

   0.001 ≤ T ₁ / T ₀ ≤ 0.5

   [In relation 2,

   T ₀ is the turbidity of the suspension solution;

   T ₁ is the turbidity of the aged composition]
9. The method of claim 8,

   The suspension solution is a method for producing a transparent solubilized cosmetic composition comprising 1 to 20 parts by weight of the diol compound, based on 1 part by weight of the fragrance.
10. The method of claim 9,

    The suspension solution is a method for producing a transparent solubilized cosmetic composition further comprises 1 to 30 parts by weight of ethanol, based on 1 part by weight of the fragrance.
11. The method of claim 8,

    The maturation is a method of producing a transparent solubilized cosmetic composition is a natural maturation that is left at 20 to 30 ℃ or artificial aging to promote molecular movement by applying external energy.

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