WO2018156814A1 - Matériau radio-opaque et utilisation pour fermetures de sac - Google Patents

Matériau radio-opaque et utilisation pour fermetures de sac Download PDF

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Publication number
WO2018156814A1
WO2018156814A1 PCT/US2018/019293 US2018019293W WO2018156814A1 WO 2018156814 A1 WO2018156814 A1 WO 2018156814A1 US 2018019293 W US2018019293 W US 2018019293W WO 2018156814 A1 WO2018156814 A1 WO 2018156814A1
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WO
WIPO (PCT)
Prior art keywords
radiopaque
bag
ceramic material
resinous
carrier resin
Prior art date
Application number
PCT/US2018/019293
Other languages
English (en)
Inventor
Donald CARRELL
Keith Hart
Original Assignee
Skm Paxton Innovations Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Skm Paxton Innovations Llc filed Critical Skm Paxton Innovations Llc
Publication of WO2018156814A1 publication Critical patent/WO2018156814A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D33/00—Details of, or accessories for, sacks or bags
    • B65D33/16—End- or aperture-closing arrangements or devices
    • B65D33/1616—Elements constricting the neck of the bag
    • B65D33/1625—Small plates or the like made of one piece and presenting slits or a central aperture to jam the neck of the bag
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/18—Layered products comprising a layer of synthetic resin characterised by the use of special additives
    • B32B27/20—Layered products comprising a layer of synthetic resin characterised by the use of special additives using fillers, pigments, thixotroping agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/18—Layered products comprising a layer of synthetic resin characterised by the use of special additives
    • B32B27/22—Layered products comprising a layer of synthetic resin characterised by the use of special additives using plasticisers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
    • B32B27/302—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising aromatic vinyl (co)polymers, e.g. styrenic (co)polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
    • B32B27/304—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising vinyl halide (co)polymers, e.g. PVC, PVDC, PVF, PVDF
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
    • B32B27/306—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising vinyl acetate or vinyl alcohol (co)polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
    • B32B27/308—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising acrylic (co)polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/34—Layered products comprising a layer of synthetic resin comprising polyamides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
    • B32B3/02—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by features of form at particular places, e.g. in edge regions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
    • B32B3/26—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layer; characterised by a layer with cavities or internal voids ; characterised by an apertured layer
    • B32B3/266—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layer; characterised by a layer with cavities or internal voids ; characterised by an apertured layer characterised by an apertured layer, the apertures going through the whole thickness of the layer, e.g. expanded metal, perforated layer, slit layer regular cells B32B3/12
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2250/00—Layers arrangement
    • B32B2250/03—3 layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2250/00—Layers arrangement
    • B32B2250/24—All layers being polymeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2264/00—Composition or properties of particles which form a particulate layer or are present as additives
    • B32B2264/10—Inorganic particles
    • B32B2264/107—Ceramic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2270/00—Resin or rubber layer containing a blend of at least two different polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/40—Properties of the layers or laminate having particular optical properties
    • B32B2307/402—Coloured
    • B32B2307/4026—Coloured within the layer by addition of a colorant, e.g. pigments, dyes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/40—Properties of the layers or laminate having particular optical properties
    • B32B2307/41—Opaque
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/50—Properties of the layers or laminate having particular mechanical properties
    • B32B2307/546—Flexural strength; Flexion stiffness
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/732—Dimensional properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2435/00—Closures, end caps, stoppers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • C08K2003/221—Oxides; Hydroxides of metals of rare earth metal
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20—Oxides; Hydroxides
    • C08K3/22—Oxides; Hydroxides of metals
    • C08K2003/2244—Oxides; Hydroxides of metals of zirconium
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K2201/00—Specific properties of additives
    • C08K2201/002—Physical properties
    • C08K2201/005—Additives being defined by their particle size in general

Definitions

  • FIG 1 shows a bag closure (100) that includes a plastic body (1 10), a bag- holding central aperture (120), which is connected to a narrow access opening (130).
  • the access opening (130) receives the neck of a flexible bag (not shown), which is then held within the central aperture (120).
  • Plastic bag closures are generally made from an extruded web or strip of a resinous material .
  • U.S. Patent Nos 3, 164,249, 3, 164,250 and 4,333,566 describe forming bag closures from strips of multi-closures interconnected by breakable tabs. Individual bag closures can be separated (by breaking the tabs) and applied to flexible bags either manually or by automatic closure-applying machines. See U.S. Patent Nos. 4,999,969 and 4,911,293.
  • radiopaque bag closures that that are readily detectable by conventional imaging techniques such as radiography. Also described are radiopaque material based on radiopaque composite resins and use thereof.
  • radiopaque bag closures comprising a flat resinous body having an access opening and a bag-holding central aperture, wherein the access opening joins the bag-holding central aperture to define a continuous space
  • the flat resinous body comprises a radiopaque composite resin having a carrier resin having one or more thermoplastic polymers and a radiopaque ceramic material dispersed in the carrier resin in a loading amount of 0.05-15% w/w. More typically, the loading amount is in the range of 0.1-10% w/w, or 0.1-5% w/w, or 0.2-5% w/w.
  • Another specific embodiment provides a radiopaque material based on a radiopaque composite resin having a carrier resin having one or more thermoplastic polymers and a radiopaque ceramic material dispersed in the carrier resin in a loading amount of 0.05-80% w/w. More typically, the loading amount is in the range of 0. J - 20%, or 0.1-10% w/w, or 0.1-5% w/w, or 0.2-5% w/w.
  • Figure 3 shows a radiopaque bag closure having a layered construction according to another embodiment of the disclosure.
  • Figure 4 shows a multi-closure strip according to one embodiment of the disclosure
  • the radiopaque composite resin includes a carrier resin and a radiopaque ceramic material dispersed therein.
  • the radiopaque composite resin and bag closures must retain its rigidity yet having sufficient flex to allow machining of muiti- closure strips and closing of the bags in manual or automated settings.
  • an organic material e.g., a carrier resin
  • the rheological properties, such as plasticity, of the carrier resin can be significantly altered, which in turn impact the handling (including machining) of the resulting composite resin.
  • bag closures formed of a radiopaque composite resin having a radiopaque ceramic material of high intrinsic radi opacity at a low loading amount.
  • the radiopaque composite resin and the bag closures made thereof address the competing technical requirements of rigidity, plasticity and flexibility.
  • a carrier resin refers to a host or matrix in which the radiopaque ceramic material is dispersed .
  • the carrier resin includes one or more thermoplastic polymers.
  • thermoplastic polymer can be any polymer material (including copolymers or blends of polymers) that is pliable, moldabie, extmdabie at a specific temperature and hardens after cooling from the specific temperature.
  • thermoplastic polymers suitable for the present disclosure includes, without limitation, polyethylene (high or low density), polypropylene, polyvinyl chloride, polystyrene, a co-polymer of polystyrene (e.g., poly(acrylonitrile butadiene styrene), poly (butadiene- co-styrene)), nylons, polyacrylate, polyvinyl acetate, and the likes.
  • thermoplastic polymers are polyethylene- vinyl acetate), poly (butadiene-co-styrene) (e.g., high-impact polystyrenes or "HIPS"), poiy(ethylene-methaciylate), acrylonitrile butadiene styrene (ABS) or combinations thereof.
  • Thermoplastic polymers typically have high molecular weight (e.g., MW
  • a radiopaque ceramic material is an inorganic, non- metallic material that obstructs electromagnetic radiations (e.g., X-rays) and thus can be detected or visualized by a radiographic imaging device. Radiopacity refers to the relative inability of electromagnetic radiation to pass through a particular material. Thus, the radiopaque ceramic material has higher intrinsic radiopacity than the carrier resin.
  • the carrier resin is typically considered radiolucent because it allows
  • electromagnetic radiations to largely pass through, e.g., in a substantially the same way as the soft tissues of the body.
  • the radiopaque ceramic material of the present disclosure preferably has high intrinsic radiopacity. At high radiopacity, the radiopaque ceramic material may be present at a low loading amount (percentage by mass relative to the carrier resin) yet still sufficient to be detectable. In various embodiments, the loading of the radiopaque ceramic material is typically in the range of 0.05-15% (w/w), 0.05-10% (w/w), 0.1-10% (w/w) or more typically, in the range of 0.1%-5% (w/w), 0.1%-2% (w/w), 0.2%-2% (w/w), 0.2-1.0%, or 0,2-0,5%.
  • radiopaque ceramic material examples include inorganic compounds derived from zirconium, bismuth or ytterbium. Specific examples include, without limitation, zirconia (Zr0 2 ), bismuth oxychloride (BiOCl) and ytterbium (III) oxide (Yb 2 0 3 ).
  • the radiopaque ceramic material is typically in a particulate form to facilitate uniform blending within the carrier resin.
  • the radiopaque ceramic material comprises micron-sized or submicron-sized particles.
  • the diameters of the particles of radiopaque ceramic material are in the range of 0.2- 20 ⁇ .
  • the particles have mean diameters in a range of 1-10 ⁇ , 2-10 ⁇ , 2-5 ⁇ or 1- ⁇ .
  • Additives such as plasticizers may be added to further fine-tune the rigidity and plasticity. Colorants or pigments may also be added.
  • the bag closures according to the present disclosures may be prepared by first extruding the radiopaque composite resin to provide a flat web or strip of a resinous body from which the bag closures are formed.
  • the flat resinous body may be in a monolithic or a layered construction.
  • the entire resinous body of the bag closure is formed of a radiopaque composite resin.
  • Figure 2 shows a bag closure in which the resinous body has a monolithic structure.
  • a bag closure (200) has a resinous body (210) having a bag-holding central aperture (220) and an access opening (230), wherein the access opening joins the bag-holding central aperture to define a continuous space, and wherein the resinous body (210) is a monolithic layer of radiopaque composite resin (240) having a carrier resin and a radiopaque ceramic material at a loading amount of 0.05-15% w/w.
  • the bag closure is about 0.03-0.09 inches thick.
  • the radiopaque composite resin extends the entire thickness of the bag closure.
  • the resinous body of the bag closure is formed of a first radiopaque layer, a second radiopaque layer, and a non-radi opaque resinous layer intermediate of the first layer and the second layer.
  • the non-radi opaque resinous layer forms the core or the bulk of the resinous body, which assumes the primary role in maintaining the necessary structural rigidity and plasticity.
  • the radiopaque layers that sandwich the intermediate core layer impart the radiopacity needed for detection.
  • the layered construction effectively reduces the total amount of the radiopaque ceramic material in the bag closure.
  • FIG. 3 shows a bag closure in which the resinous body has a layered structure.
  • a bag closure (300) has a layered resinous body (310) having a bag-holding central aperture (320) and an access opening (330), wherein the access opening joins the bag-holding central aperture to define a continuous space
  • the resinous body (310) comprises a first radiopaque layer of a first radiopaque composite resin (340) having a first carrier resin and a first radiopaque ceramic material at a loading amount of 0.05-15% w/w; a second radiopaque lay er of a second radiopaque composite resin (350) having a second carrier resin and a second radiopaque ceramic material at a loading amount of 0.05-15% w/w, and a non-radiopaque resinous layer (360) intermediate of the first radiopaque layer and radiopaque second layer.
  • the first radiopaque composite resin is identical to the second radiopaque composite resin, i.e., having the same carrier resin and the same the radiopaque ceramic material at the same loading amount.
  • the intermediate non-radiopaque resinous layer comprises the same carrier resin as that of the first and second radiopaque layers.
  • the several layers are cohesively bonded together owing to the presence of the same carrier resin in each layer.
  • the intermediate non-radiopaque resinous layer typically takes up 50-85%, or more typically, 60-80% by weight of the entire resinous body of the bag closure.
  • the remainder of the resinous body is divided evenly between the first radiopaque layer and the second radiopaque layer.
  • the layered resinous body is composed of 10%
  • the multi-layer bag closures typically are 0.03-0.09 inches thick, whereby the first and second radio opaque layers are about 0.003-0.009 inches thick, wherein the intermediate layer is about 0.024-0.072 inches thick.
  • the bag closures of the present disclosures may be prepared by any of the methods disclosed U.S. Patent Nos 3, 164,249, 3, 164,250, 4,333,566 4,999,969 and 4,911,293 by using a radiopaque composite resin according to the present disclosure in the place of the conventional resins.
  • the bag closures of the present disclosure may be prepared by extruding the radiopaque composite resin to form a flat resinous web of about 0.03-0.09 inches thick; forming one or more multi-closure strips from the flat resinous web, and separating individual bag closures from the multi- closure strip.
  • One embodiment thus provides a multi-closure strip.
  • Figure 4 shows a multi-closure strip (400) of a plurality of bag closures (200) (only two are shown).
  • the bag closures (200) are the same as shown in Figure 2, except that the two adjacent bag closures (200) are connected by one or more tabs (240). These tabs can be broken off to cause separation of the bag closures (200) from one another.
  • the tabs may be in any configurations so long as they can sustain the machining process and be broken off when a specific force is applied. See e.g., US 4,333,566.
  • bag closures of a layered construction can be made from multi-closure strips of a layered construction, the several layers being simultaneously co-extruded to form a fiat resinous web of a layered structure, which can be machined into one or more multi-closure strips, and separated into individual bag closures.
  • a bulk resinous material with a higher loading of radiopaque ceramic material and additional carrier resin are separately fed (from separate hoppers) at a predetermined let-down ratio, and the two are blended to provide the desired loading of the radiopaque ceramic materi al.
  • the bulk radiopaque composite resin may comprise up to a loading amount of 40-80%, or 50%- 80% of the radiopaque ceramic material . Blending of the two feeds provides a radiopaque composite resin having the desire radiopacity.
  • a further embodiment provides a radiopaque material based on a radiopaque composite resin.
  • a radiopaque material based on a radiopaque composite resin.
  • Such a material is broadly suitable for uses or applications in which radiopacity provides a means for detection. For instance, toys or toy parts are the most common foreign objects that can be accidentally ingested by children.
  • the radiopaque material comprises a radiopaque composite resin having a carrier resin and 0.05-80% (or more typically 1-80%) of a radiopaque ceramic material includes one or more compounds derived from zirconium, bismuth or ytterbium.
  • the carrier resin comprises one or more thermoplastic polymers, including for example, polyethylene (high or low density), polypropylene, polyvinyl chloride, polystyrene or a co-polymer thereof (e.g., poiyfacrylonitriie butadiene styrene), poly (butadiene-co-styrene)), nylons,
  • thermoplastic polymers including for example, polyethylene (high or low density), polypropylene, polyvinyl chloride, polystyrene or a co-polymer thereof (e.g., poiyfacrylonitriie butadiene styrene), poly (butadiene-co-styrene)), nylons,
  • the radiopaque ceramic material is zirconia (Zr0 2 ), bismuth oxychioride (BiOCl), ytterbium (III) oxide (Yb 2 0 3 ), or a combinati on thereof.
  • the radiopaque material may further comprises additives such as one or more colorants, one or more plasticizers and the like. Additives may be combined with the radiopaque composite resin according to known methods in the art.

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne des fermetures de sac radio-opaques comprenant un corps plat en résine ayant une ouverture d'accès et une ouverture centrale de maintien de sac, dans lesquels l'ouverture d'accès rejoint l'ouverture centrale de maintien de sac pour définir un espace continu, et dans lesquels le corps plat en résine comprend une résine composite radio-opaque ayant une résine porteuse ayant un ou plusieurs polymères thermoplastiques et un matériau céramique radio-opaque dispersé dans la résine porteuse en une quantité de charge de 0,05 à 15% en poids/poids.
PCT/US2018/019293 2017-02-22 2018-02-22 Matériau radio-opaque et utilisation pour fermetures de sac WO2018156814A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762462216P 2017-02-22 2017-02-22
US62/462,216 2017-02-22

Publications (1)

Publication Number Publication Date
WO2018156814A1 true WO2018156814A1 (fr) 2018-08-30

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Citations (3)

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Publication number Priority date Publication date Assignee Title
US3164250A (en) * 1963-11-22 1965-01-05 Kwik Lok Polystyrene multi-closure strip adapted for separation into individual closures
US20040137117A1 (en) * 2003-01-09 2004-07-15 Axelrod Glen S. Radiopaque animal chew
US20040229971A1 (en) * 2003-05-16 2004-11-18 Massimo Rossi Radiopaque and aseptic material for impression-taking

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
US3164250A (en) * 1963-11-22 1965-01-05 Kwik Lok Polystyrene multi-closure strip adapted for separation into individual closures
US20040137117A1 (en) * 2003-01-09 2004-07-15 Axelrod Glen S. Radiopaque animal chew
US20040229971A1 (en) * 2003-05-16 2004-11-18 Massimo Rossi Radiopaque and aseptic material for impression-taking

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Title
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NEWELL, KJ.: "Plastic bread-bag clips in the gastrointestinal tract: report of 5 cases and review of the literature", CANADIAN MEDICAL ASSOCIATION JOURNAL, vol. 162, no. 4, 22 February 2000 (2000-02-22), pages 527 - 529, XP055535536 *

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