WO2018147472A1 - Biomarqueur sanguin - Google Patents

Biomarqueur sanguin Download PDF

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Publication number
WO2018147472A1
WO2018147472A1 PCT/JP2018/005603 JP2018005603W WO2018147472A1 WO 2018147472 A1 WO2018147472 A1 WO 2018147472A1 JP 2018005603 W JP2018005603 W JP 2018005603W WO 2018147472 A1 WO2018147472 A1 WO 2018147472A1
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WO
WIPO (PCT)
Prior art keywords
blood
acid
concentration
group
microorganism
Prior art date
Application number
PCT/JP2018/005603
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English (en)
Japanese (ja)
Inventor
賢 石井
宜広 磯貝
Original Assignee
学校法人慶應義塾
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 学校法人慶應義塾 filed Critical 学校法人慶應義塾
Priority to JP2018567548A priority Critical patent/JPWO2018147472A1/ja
Publication of WO2018147472A1 publication Critical patent/WO2018147472A1/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un biomarqueur sanguin de micro-organismes et un procédé de détermination d'une infection par des micro-organismes à l'aide du biomarqueur sanguin. Ce biomarqueur sanguin est caractérisé en ce qu'il comprend au moins une substance dans le cycle TCA choisie parmi l'acide α-cétoglutarique, la succinyl-CoA, l'acide succinique, l'acide fumarique et l'acide malique.
PCT/JP2018/005603 2017-02-09 2018-02-09 Biomarqueur sanguin WO2018147472A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2018567548A JPWO2018147472A1 (ja) 2017-02-09 2018-02-09 血中バイオマーカー

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017-022018 2017-02-09
JP2017022018 2017-02-09

Publications (1)

Publication Number Publication Date
WO2018147472A1 true WO2018147472A1 (fr) 2018-08-16

Family

ID=63107669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2018/005603 WO2018147472A1 (fr) 2017-02-09 2018-02-09 Biomarqueur sanguin

Country Status (2)

Country Link
JP (1) JPWO2018147472A1 (fr)
WO (1) WO2018147472A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009523435A (ja) * 2006-01-19 2009-06-25 エントレス アーベー 診断方法及び治療方法
US20100136600A1 (en) * 2007-04-12 2010-06-03 Carolyn Slupsky Urine based detection of a disease state caused by a pneumococcal infection
JP2010538968A (ja) * 2007-06-01 2010-12-16 ザ トラスティーズ オブ プリンストン ユニバーシティ 宿主細胞代謝経路の調節によるウイルス感染治療
JP2012024555A (ja) * 2010-06-24 2012-02-09 Institute Of Physical & Chemical Research 疲労のバイオマーカーおよびその利用
US20120197539A1 (en) * 2009-10-09 2012-08-02 Carolyn Slupsky Methods for diagnosis, treatment and monitoring of patient health using metabolomics

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009523435A (ja) * 2006-01-19 2009-06-25 エントレス アーベー 診断方法及び治療方法
US20100136600A1 (en) * 2007-04-12 2010-06-03 Carolyn Slupsky Urine based detection of a disease state caused by a pneumococcal infection
JP2010538968A (ja) * 2007-06-01 2010-12-16 ザ トラスティーズ オブ プリンストン ユニバーシティ 宿主細胞代謝経路の調節によるウイルス感染治療
US20120197539A1 (en) * 2009-10-09 2012-08-02 Carolyn Slupsky Methods for diagnosis, treatment and monitoring of patient health using metabolomics
JP2012024555A (ja) * 2010-06-24 2012-02-09 Institute Of Physical & Chemical Research 疲労のバイオマーカーおよびその利用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEWTON, P. B. ET AL.: "Some biochemical effects of the microsporidian nosema whitei on the blood components of tribolium castaneum using disc electrophoresis", COMP. BIOCHEM. PHYSIOL. B, vol. 74, no. 3, 1983, pages 553 - 558, XP025755763 *

Also Published As

Publication number Publication date
JPWO2018147472A1 (ja) 2020-01-16

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