WO2018139099A1 - Récipient de mise au rebut de cellule d'analyse, cellule d'analyse pouvant être mise au rebut et kit de cellule d'analyse pouvant être mis au rebut - Google Patents

Récipient de mise au rebut de cellule d'analyse, cellule d'analyse pouvant être mise au rebut et kit de cellule d'analyse pouvant être mis au rebut Download PDF

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Publication number
WO2018139099A1
WO2018139099A1 PCT/JP2017/045014 JP2017045014W WO2018139099A1 WO 2018139099 A1 WO2018139099 A1 WO 2018139099A1 JP 2017045014 W JP2017045014 W JP 2017045014W WO 2018139099 A1 WO2018139099 A1 WO 2018139099A1
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WO
WIPO (PCT)
Prior art keywords
analysis
analysis cell
cell
coupled
coupling
Prior art date
Application number
PCT/JP2017/045014
Other languages
English (en)
Japanese (ja)
Inventor
典弘 松山
Original Assignee
株式会社ダナフォーム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社ダナフォーム filed Critical 株式会社ダナフォーム
Publication of WO2018139099A1 publication Critical patent/WO2018139099A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system

Definitions

  • the present invention relates to an analysis cell disposal container, a disposal analysis cell, and an analysis cell disposal kit.
  • the analysis cell that has been analyzed contains the biological sample, and depending on the biological sample, there may be cases in which an analyzer or an object that pollutes the environment such as a laboratory in which analysis is performed is included. is there.
  • an analyzer or an object that pollutes the environment such as a laboratory in which analysis is performed is included.
  • the analyst may be secondaryly infected by contact with the analysis cell.
  • a detection system that performs nucleic acid amplification for example, if the amplified product after the analysis leaks out of the system, there is a possibility that subsequent detection performed near the leakage area may be disabled.
  • an object of the present invention is to provide a tool for safely discarding an analysis cell after completion of analysis, for example, regardless of the risk level of a sample to be analyzed.
  • the analysis cell waste container of the present invention comprises: A storage chamber, a coupling portion and a coupling release portion;
  • the containment chamber is Having a storage space for the analysis cell; Has an openable and closable opening,
  • the coupling portion is It is a coupling part that can be coupled with the analysis cell,
  • the uncoupling part is A release unit capable of releasing the coupling between the analysis cell and the analysis device; while using it, In the state where the opening of the storage chamber is opened, the analysis cell in a state inserted into the analysis device is stored inside the storage chamber, Combined with the analysis cell by the combining unit, Release the coupling between the analysis cell and the analysis device by the coupling release unit, Pull out the analytical device from the containment chamber, The opening of the storage chamber is closed in a state where the analysis cell is stored in the storage chamber.
  • the disposal analysis cell of the present invention has an analyzed part, a first coupled part, and a second coupled part,
  • the first coupled portion is A coupled portion that can be coupled to an analytical device;
  • the second coupled portion is It is a coupled part that can be coupled with the analysis cell waste container, At the start of analysis, The first coupled portion is coupled to the analysis device, After the analysis The second coupled part is coupled to the coupling part of the analysis cell disposal container, The coupling with the analysis device in the first coupled part is released by the coupling releasing part of the analysis cell disposal container.
  • the analysis cell disposal kit of the present invention includes the analysis cell waste container of the present invention and the analysis cell of the present invention.
  • the analysis device of the present invention includes a coupling unit and an analysis unit, and the coupling unit is a coupling unit that can be coupled to the first coupled unit of the analysis cell of the present invention.
  • an analyst can discard the analysis cell without directly touching the analysis cell after completion of the analysis and without exposing the analysis cell to the analysis environment. For this reason, high safety can be ensured.
  • FIG. 1 is a perspective view illustrating an example of an analysis cell and an analysis device according to the first embodiment.
  • FIG. 2 is a perspective view showing an outline of an analysis cell waste container and a method for using the same in the first embodiment.
  • FIG. 3 is a plan view illustrating an outline of an example of an analysis cell, an analysis device, and an analysis cell waste container in the second embodiment.
  • FIG. 4 is a plan view schematically showing a method for using the analysis cell waste container in the second embodiment.
  • FIG. 5 is a plan view showing an outline of a method of using the analysis cell waste container in the second embodiment.
  • the coupling unit also serves as the releasing unit, and the coupling unit is coupled to the analysis cell, and the coupling between the analysis cell and the analysis device is released. .
  • the storage chamber has a bag shape.
  • the storage chamber is flexible.
  • the opening of the storage chamber has a chuck portion, and can be opened and closed by the chuck portion.
  • the storage chamber has a gripping portion at the other end of the opening.
  • the grip portion is a handle type.
  • Embodiment 1 demonstrates an example of an analysis cell disposal container using a figure.
  • the analysis cell 10 has a gripping portion 101 and an analysis substrate 102.
  • the gripping portion 101 has a portion 104 to be coupled to an analysis cell disposal container described later.
  • a plurality of reaction units 103 In each of the plurality of reaction units 103, for example, a part or all of the reaction units 103 are analyzed units analyzed by the analysis device.
  • the analysis device 20 has a storage chamber 201 that stores the analysis cell 10. When the sample is added to the reaction unit 103 of the analysis cell 10 in use, the analysis cell 10 is inserted into the storage chamber 201 of the analysis device 20 as shown in FIG. As shown in FIG. 2, the analysis substrate 102 of the analysis cell 10 is accommodated in the accommodation chamber 201 of the analysis device 20 and reacted.
  • FIG. 2 is a perspective view schematically showing the use of the analysis cell waste container 30 and the analysis cell waste container 30.
  • the analysis cell waste container 30 has a storage chamber 301.
  • the storage chamber 301 has a bag shape with one open, and has an openable / closable chuck portion 303 on the opening 302 side.
  • the storage chamber 301 has a storage space in which the analysis cell 10 inserted in the analysis device 20 can be stored.
  • the storage chamber 301 has a fixing portion 306 on the side opposite to the opening 302, and a holding portion 305 is fixed to the fixing portion 306 toward the outside of the storage chamber 301, and toward the inside of the storage chamber 301.
  • the coupling portion 304 is fixed.
  • the grip 305 is a handle type and is a part for facilitating the handling of the analysis cell waste container 30.
  • the coupling unit 304 serves as a coupling unit that can be coupled to the analysis cell 10 and a release unit that can decouple the analysis cell 10 and the analysis device 20.
  • the analysis cell 10 is accommodated in the accommodation chamber 301 while being inserted into the analysis device 20 from the opening 302 of the analysis cell disposal container 30.
  • the analysis cell disposal container 30 and the analysis cell 10 are fixed by coupling the coupling portion 304 of the analysis cell disposal container 30 with the coupled portion 104 of the analysis cell 10, and the analysis cell 10 and the analysis device are fixed. 20 is released.
  • the mechanism for coupling with the analysis cell 10 and the coupling release between the analysis cell 10 and the analysis device 20 by the coupling unit 304 of the analysis cell disposal container 30 is not particularly limited. An example of the mechanism will be described later.
  • the analysis cell disposal container 30 is coupled to the analysis cell 10 by the coupling unit 304, and the coupling between the analysis cell 10 and the analysis device 20 is released. Therefore, as shown in FIG. 2C, by pulling the grip portion 305 of the analysis cell waste container 30 in the direction opposite to the analysis device 20, the analysis cell waste container 30 and the analysis cell 10 coupled thereto are obtained. Separate from the analysis device 20. As a result, the analysis cell 10 is accommodated in the accommodation chamber 301 of the analysis cell disposal container 30 as shown in FIG. Then, as shown in FIG. 2D, the chuck of the analysis cell waste container 30 is closed. As a result, the analysis cell 10 can be discarded while being stored in the storage chamber 301 of the analysis cell disposal container 30 without being exposed to the outside. Thereby, for example, the amplified product after analysis can be prevented from leaking out of the system.
  • the analysis cell disposal container 30 accommodates the analysis cell 10 in a state of being coupled to the analysis device 20 in the storage chamber 301, and after separating the analysis device 20 from the analysis cell 10, the opening 302 is formed in the chuck portion 303. Need to close.
  • the storage chamber 301 is preferably formed of, for example, a flexible material.
  • the flexible material include polyolefins such as polyethylene, polypropylene, polytetrafluoroethylene, and polybutylene terephthalate; polyvinyl chloride such as soft polyvinyl chloride; polyvinyl alcohol; ethylene-vinyl acetate copolymer resin; silicon; Examples thereof include resins such as nylon.
  • the storage chamber 301 is preferably a transparent member or a translucent member so that the inside can be confirmed, for example.
  • the opening 302 of the analysis cell disposal container 30 only needs to be openable and closable.
  • the opening and closing is performed by the chuck portion 303 as described above.
  • the opening and closing by the chuck portion 303 is, for example, a slide type.
  • the type of the analysis cell 10 is not particularly limited, and examples thereof include cells used for nucleic acid amplification reaction systems, antigen-antibody reaction systems, and the like.
  • Embodiment 2 demonstrates an example of the mechanism of the coupling
  • FIG. 3 to 4 are schematic views showing a coupling and decoupling mechanism between the analysis cell, the analysis device, and the analysis cell waste container.
  • FIG. 3 is a plan view schematically showing an analysis cell, an analysis device, and an analysis cell waste container. 3 and 4 are for the purpose of explaining the outline of the mechanism, and the other configurations are omitted.
  • FIG. 3A is a plan view of the analysis cell 10, and a pair of coupled portions 104 for coupling to the analysis device 20 and the analysis cell waste container 30 at both ends in the direction perpendicular to the coupling direction to the analysis device 20.
  • the coupled portion 104 is concave.
  • FIG. 3B is a plan view of the analysis device 20, and has a pair of coupling portions 204 for coupling with the analysis cell 10 at both ends in the direction perpendicular to the coupling direction with the analysis cell 10.
  • the pair of coupling portions 204 has a hook portion 204a with respect to the inner direction at one end and a fulcrum 204b fixed at the other end.
  • FIG. 3C is a plan view of the analysis cell waste container 30, which is coupled to the analysis cell 10 at both ends in the direction perpendicular to the coupling direction to the analysis cell 10, and the analysis cell 10 and the analysis device. 20 has a pair of coupling portions 304 for releasing the coupling with the unit 20.
  • the pair of coupling portions 304 has a hooking portion 304a for the inner direction at one end.
  • the analysis cell 10 is coupled to the analysis device 20. As shown in FIGS. 4A and 4B, the analysis cell 10 is inserted into the analysis device 20 in the direction of the arrow. When the analysis cell 10 is completely inserted into the analysis device 20, the hook portion 204 a of the coupling portion 204 of the analysis device 20 is hooked on the concave coupled portion 104 of the analysis cell 10, and the analysis cell 10 is attached to the analysis device 20. Fixed.
  • an analysis cell waste container 30 is prepared for the analysis cell 10 fixed to the analysis device 20 shown in FIG. 4C, and as shown in FIG.
  • the analysis cell waste container 30 is put on the analysis cell 10 fixed in the analysis device 20.
  • the tip of the coupling portion 304 of the analysis cell disposal container 30 hits the tip of the hook portion 204a of the coupling portion 204 in the analysis device 20, and the concave coupled portion of the analysis cell 10 is obtained.
  • 104 and the hooking part 204a of the analysis device 20 are released.
  • the hooking portion 304a of the coupling portion 304 in the analysis cell disposal container 30 is hooked on the concave coupled portion 104 of the analysis cell 10, and the analysis cell 10 is released from the coupling with the analysis device 20, and the analysis cell disposal container 30 is fixed.
  • the analysis device 20 is gripped and the analysis cell waste container 30 is pulled in the direction of the arrow, so that the analysis device 20 is fixed to the analysis cell waste container 30.
  • the analyzed analysis cell 10 can be pulled out. Since the extracted analysis cell 10 is stored in the storage chamber 301 of the analysis cell disposal container 30, it can be discarded without being exposed to the outside by closing the opening 302 as described above.
  • the release of the connection between the analysis device 20 and the analysis cell 10 is not limited to these embodiments, and may be released by, for example, a dedicated lock release device.
  • the unlocking device hits the tip of the hooking portion 204a of the coupling portion 204 in the analysis device 20 in the same manner as the tip of the coupling portion 304 of the analysis cell disposal container 30, and the concave coupled portion of the analysis cell 10 is connected.
  • the part 104 and the hooking part 204a of the analysis device 20 may have a part that releases the hook.
  • an analyzer can discard the analysis cell without directly touching the analysis cell after completion of the analysis and without exposing the analysis cell to the analysis environment. For this reason, high safety can be ensured.

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
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  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
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  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

L'invention concerne un outil permettant de mettre au rebut en toute sécurité une cellule d'analyse après achèvement de l'analyse quel que soit le niveau de danger d'un échantillon qui est analysé. Un récipient de mise au rebut de cellule d'analyse selon la présente invention est caractérisé en ce qu'il comprend une chambre de réception, une partie de mise en prise et une partie de libération de la prise, et est caractérisé en ce que la chambre de réception comprend un espace pour recevoir une cellule d'analyse et a une ouverture qui peut être ouverte et fermée, la partie de mise en prise est une partie de mise en prise qui peut entrer en prise avec la cellule d'analyse, la partie de libération de la prise est une partie de libération qui peut libérer la prise mutuelle de la cellule d'analyse et d'un dispositif d'analyse, et, lors de l'utilisation, avec l'ouverture de la chambre de réception ouverte, la cellule d'analyse insérée dans le dispositif d'analyse est logée à l'intérieur de la chambre de réception, la cellule d'analyse est amenée en prise en utilisant la partie de prise, la prise mutuelle de la cellule d'analyse et du dispositif d'analyse est libérée à l'aide de la partie de libération de la prise, le dispositif d'analyse est retiré de la chambre de réception, et avec la cellule d'analyse logée dans la chambre de réception, l'ouverture de la chambre de réception est fermée.
PCT/JP2017/045014 2017-01-25 2017-12-15 Récipient de mise au rebut de cellule d'analyse, cellule d'analyse pouvant être mise au rebut et kit de cellule d'analyse pouvant être mis au rebut WO2018139099A1 (fr)

Applications Claiming Priority (2)

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JP2017011682 2017-01-25
JP2017-011682 2017-01-25

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Publication Number Publication Date
WO2018139099A1 true WO2018139099A1 (fr) 2018-08-02

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PCT/JP2017/045014 WO2018139099A1 (fr) 2017-01-25 2017-12-15 Récipient de mise au rebut de cellule d'analyse, cellule d'analyse pouvant être mise au rebut et kit de cellule d'analyse pouvant être mis au rebut

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009042227A (ja) * 2007-08-02 2009-02-26 F Hoffmann-La Roche Ag テストエレメントの転送装置
WO2013038691A1 (fr) * 2011-09-14 2013-03-21 パナソニック株式会社 Dispositif d'alimentation en capteurs de détection d'informations biologiques
WO2013042536A1 (fr) * 2011-09-20 2013-03-28 テルモ株式会社 Dispositif de mesure de composants

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009042227A (ja) * 2007-08-02 2009-02-26 F Hoffmann-La Roche Ag テストエレメントの転送装置
WO2013038691A1 (fr) * 2011-09-14 2013-03-21 パナソニック株式会社 Dispositif d'alimentation en capteurs de détection d'informations biologiques
WO2013042536A1 (fr) * 2011-09-20 2013-03-28 テルモ株式会社 Dispositif de mesure de composants

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