WO2018117451A1 - Dispositif d'imagerie optique pourvu d'une source de lumière couplée - Google Patents

Dispositif d'imagerie optique pourvu d'une source de lumière couplée Download PDF

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Publication number
WO2018117451A1
WO2018117451A1 PCT/KR2017/013598 KR2017013598W WO2018117451A1 WO 2018117451 A1 WO2018117451 A1 WO 2018117451A1 KR 2017013598 W KR2017013598 W KR 2017013598W WO 2018117451 A1 WO2018117451 A1 WO 2018117451A1
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Prior art keywords
light
image
wavelength
light source
narrow band
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PCT/KR2017/013598
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English (en)
Korean (ko)
Inventor
배영민
강동구
진승오
신기영
장민혜
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한국전기연구원
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Publication of WO2018117451A1 publication Critical patent/WO2018117451A1/fr

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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0655—Control therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/32—Micromanipulators structurally combined with microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
    • G02B27/0927—Systems for changing the beam intensity distribution, e.g. Gaussian to top-hat
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/0001—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems
    • G02B6/0011—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being planar or of plate-like form
    • G02B6/0066—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being planar or of plate-like form characterised by the light source being coupled to the light guide
    • G02B6/0073—Light emitting diode [LED]

Definitions

  • the present invention relates to an optical imaging apparatus, and more particularly, to generate a white light image and a narrow band light image by simultaneously or selectively irradiating light generated by the white light source and the narrow band light source to a sample at a predetermined time interval.
  • An optical imaging device to generate a white light image and a narrow band light image by simultaneously or selectively irradiating light generated by the white light source and the narrow band light source to a sample at a predetermined time interval.
  • An optical imaging apparatus refers to a device that generates and provides an optical image of a sample to be observed by a user. More specifically, examples of the optical imaging device include an endoscope used in medical or industrial fields, and the like, and various optical imaging devices are used in various fields.
  • the optical imaging apparatus may include a light source unit generating a predetermined light irradiated to a sample to be observed and a light detector detecting a light reflected or emitted from the sample. Furthermore, in recent years, various attempts have been made to improve or impart a quality of an image in the optical imaging apparatus.
  • a narrow band light image that can improve the contrast (contrast) of the affected image using a narrow band light source of a specific wavelength Imaging (NBI) technology is in the spotlight.
  • the narrowband light imaging technique may obtain an image having improved contrast by irradiating narrowband light having a wavelength similar to the absorption wavelength band of the affected part to the affected part and detecting light reflected or emitted from the affected part.
  • an endoscope image is generated by irradiating narrow band visible light of 415 nm and 540 nm bands corresponding to hemoglobin to produce an endoscopic image having improved contrast of blood vessel tissue. It can be generated, thereby making it possible to more clearly diagnose the affected area.
  • FIG. 1 an endoscope image (FIG. 1B) in which contrast of blood vessel tissue is improved using a conventional endoscope image (FIG. 1A) and the narrow band light source is illustrated.
  • a narrow band light having a specific wavelength is added by adding a narrow band transmission filter to a broadband light source such as a Xenon lamp or the like.
  • a broadband light source such as a Xenon lamp or the like.
  • the production method was used.
  • the xenon lamp not only has a short lifespan, but also a large amount of power may be consumed for driving the system, thus making it difficult to operate and manage the system, and also the light output of the narrow band light passing through the narrow band pass filter.
  • degree is greatly reduced, and there are considerable restrictions on use.
  • an optical image of a sample may be generated by selectively transmitting white light and narrow band light using a filter wheel having a narrow band transmission filter.
  • the endoscope image of the white light and the narrowband light image of the narrowband light can be selectively provided, but the two images cannot be simultaneously provided in real time. By combining them into a single image, it is difficult to generate and provide an image having more improved characteristics.
  • the present invention has been made to solve the above problems, and an object of the present invention is to provide an optical imaging apparatus capable of simultaneously providing a white light image by white light and a narrow band light image by narrow band light in real time.
  • Another object of the present invention is to provide an optical imaging apparatus capable of providing an optical image having improved characteristics such as contrast by combining a white light image by white light and a narrowband light image by narrowband light.
  • An optical imaging apparatus for solving the above problems is an optical imaging apparatus for generating an optical image of the sample by irradiating predetermined light with a sample, the narrow-band light source unit for generating a narrow band light ; A white light source unit generating white light; A light transmission unit for transmitting the light generated by the narrow band light source unit and the white light source unit to irradiate the sample; A light detector detecting light reflected or emitted from the sample; A controller which controls the narrowband light source unit and the white light source unit at predetermined time intervals; And an optical image generator for generating a white light image and a narrow band light image of the sample by using the light detected by the light detector according to the predetermined time interval.
  • the optical image generating unit may generate while switching the white light image and the narrow-band light image in accordance with the time interval.
  • the controller may be configured to control only the narrowband light to be irradiated to the sample in a section for generating a narrowband light image, and to control only the white light to be irradiated to the sample or to irradiate both the white light and the narrowband light together in a section for generating a white light image.
  • the controller may control operations of the narrowband light source unit and the white light source unit at predetermined time intervals to generate both a white light image by the white light and a narrowband light image by the narrowband light in real time. .
  • the optical image generator may generate an optical image having improved contrast by performing image processing on the white light image by the white light and the narrow-band light image by the narrow-band light.
  • the light coupling unit may further include an optical coupling unit configured to receive light generated by the white light source unit and the narrow band light source unit and output the light to the light transmitting unit.
  • the optical coupling unit may be generated by the narrowband light source unit and the white light source separated from each other to reflect or refract the incident narrowband light and white light therein and output the same to the light transmitting unit through the same output path.
  • the narrowband light generating unit may include a light emitting device emitting light of a first wavelength, and a wavelength converting unit converting light of the first wavelength into narrowband light of another wavelength.
  • the wavelength converter may convert light of the first wavelength into narrowband light of a plurality of different wavelengths.
  • the narrowband light generating unit may further include an optical filter unit blocking the light of the first wavelength and transmitting the light of the other wavelength.
  • the wavelength conversion unit may include a substrate that transmits light of the other wavelength, and a light conversion layer formed on the substrate to convert light of the first wavelength into light of the other wavelength.
  • the white light source and the narrow-band light source at the same time or selectively irradiate the sample at a predetermined time interval and the white light image and narrow band light
  • the white light source and the narrow-band light source at the same time or selectively irradiate the sample at a predetermined time interval and the white light image and narrow band light
  • the present invention is to configure the optical image through the image processing of the white light image and the narrow band light image, thereby combining the white light image by the white light and the narrow band light image by the narrow band light to obtain an optical image having improved characteristics such as contrast It has the effect that it can provide.
  • 1 is an exemplary view of a conventional narrowband endoscope image.
  • FIG. 2 is a view for explaining the operation of the optical imaging apparatus according to the prior art.
  • FIG. 3 is a block diagram of an optical imaging apparatus according to an embodiment of the present invention.
  • FIG. 4 is a diagram illustrating an operation of an optical imaging apparatus according to an exemplary embodiment of the present invention.
  • FIG. 5 is a diagram illustrating various examples of an optical coupling unit in an optical imaging apparatus according to an exemplary embodiment.
  • FIG. 6 is a diagram illustrating an operation of an optical imaging apparatus according to an exemplary embodiment.
  • FIG. 7 is a diagram illustrating a configuration of a narrow band light source unit according to an embodiment of the present invention.
  • FIG. 8 is a diagram illustrating a structure of an optical wavelength conversion unit in an optical imaging apparatus according to an embodiment of the present invention.
  • FIG. 9 is a flowchart of an optical image generating method according to an embodiment of the present invention.
  • FIG. 3 illustrates a configuration diagram of the optical imaging apparatus 100 according to an embodiment of the present invention.
  • the optical imaging apparatus 100 in the optical imaging device for generating an optical image for the sample by irradiating a predetermined light to the sample, narrowband light Narrow band light source unit 110 for generating a, White light source unit 120 for generating white light, Light transmission unit for transmitting the light generated by the narrow band light source unit 110 and the white light source unit 120 to irradiate the sample ( 140, a light detector 150 for detecting light reflected or emitted from the sample, a controller 160 for controlling operations of the narrow band light source unit 110 and the white light source unit 120 according to a predetermined time interval;
  • the optical image generating unit 170 may be configured to generate a white light image and a narrow band light image of the sample using light detected by the light detector 150 at a predetermined time interval.
  • the optical imaging apparatus 100 receives light generated by the white light
  • FIG. 4 illustrates an operation of the optical imaging apparatus 100 according to an exemplary embodiment.
  • the narrow band light source unit 110 generates narrow band light of the first wavelength
  • the white light source unit 120 generates white light.
  • the light coupling unit 130 receives the light generated by the white light source unit 120 and the narrow band light source unit 110 and outputs the light to the light transmitting unit 140.
  • the photodetector 150 detects light reflected or emitted from the sample.
  • control unit 160 controls the operations of the narrow band light source unit 110 and the white light source unit 120 according to a predetermined time interval, and accordingly, the optical image generating unit 170 controls the predetermined time.
  • the control unit 160 controls the operations of the narrow band light source unit 110 and the white light source unit 120 according to a predetermined time interval, and accordingly, the optical image generating unit 170 controls the predetermined time.
  • the narrowband light and the white light may be irradiated onto the sample at the same time at a predetermined time interval, and the optical image may be generated.
  • the white light image and the narrow-band light image are simultaneously generated while the operation mode is changed very quickly (without the mechanical operation of the filter wheel, etc. according to the prior art). You can do it.
  • the controller 160 of the optical imaging apparatus 100 may control whether light is generated in the narrow band light source unit 110 and the white light source unit 120. Furthermore, the controller 160 may control to selectively generate light in one of the narrow band light source 110 and the white light source 120 at predetermined time intervals. In particular, the white light image and the white light generated by the white light may be controlled. Optionally selected from one of the narrow band light source unit 110 and the white light source unit 120 at a short periodic interval (for example, 5 to 30 times per second) so as to generate all narrow band images by narrow band light in real time. By controlling the light to be generated, the optical image generating unit 170 of the optical imaging apparatus 100 according to the present invention can simultaneously provide the white light image and the narrow band light image in real time.
  • the optical image generating unit 170 switches the white light image and the narrow band light image at a time interval in which the control unit 160 controls the operation of the narrow band light source unit 110 and the white light source unit 120.
  • the white light image and the narrow band image of the sample can be simultaneously generated in real time.
  • the controller 160 controls the narrow band light to be irradiated to the sample only in a section generating a narrow band light image, whereas in the section generating a white light image, only white light is irradiated to the sample or white light and a narrow band light are emitted. It can also be controlled to be irradiated together.
  • control unit 160 may not only allow light to be selectively generated in one of the narrow band light source unit 110 and the white light source unit 120, and furthermore, the narrow band light source unit 110 and the By controlling the light to be generated in both the white light source unit 120 may improve the color rendering (CRI) of the white light.
  • CRI color rendering
  • the controller 160 controls the operation of the narrowband light source unit 110 and the white light source unit 120 at short intervals (for example, 5 to 30 or more times per second) while the white light image and the narrowband light are controlled.
  • the optical image generating unit 170 of the optical imaging apparatus 100 combines the white light image and the narrow band light image to improve the contrast and other characteristics. You can also provide video.
  • the narrow band light source unit 110 generates narrow band light having a wavelength of 415 nm corresponding to hemoglobin
  • the white light source unit 120 generates white light.
  • the control unit 160 controls to selectively generate light in one of the narrow band light source unit 110 and the white light source unit 120 at a short periodic interval (for example, 5 to 30 or more times per second).
  • the photodetector 150 sequentially generates detection data at 415 nm wavelength and detection data at white light in accordance with the period.
  • the optical image generating unit 170 reconstructs the narrowband light image having improved contrast of the vascular tissue by the detection data at the 415 nm wavelength, and reconstructs the white light image by the detection data of the white light.
  • the narrowband light image and the white light image can be simultaneously provided in real time.
  • the optical image generating unit 170 improves contrast of blood vessel tissue through image processing of a narrowband light image by the detection data at the 415 nm wavelength and a white light image by the detection data at the white light.
  • the white light optical image can be reconstructed and provided in real time.
  • optical imaging apparatus 100 according to an exemplary embodiment of the present invention will be described in more detail with reference to FIGS. 3 and 4.
  • the narrow band light source unit 110 generates narrow band light of a first wavelength.
  • the narrow band light source unit 110 may use various light emitting devices such as a light emitting diode (LED) or a laser. Particularly, when the light emitting diode (LED) is used as the light emitting device in the narrow band light source unit 110, it is possible to quickly adjust whether the light emitting diode (LED) is emitted and the light output (intensity) through electrical control. Can have
  • LED light emitting diode
  • the light emitting diode (LED) emits light it is possible to adjust whether to generate narrow band light. Furthermore, the narrow band light image and the white light image are simultaneously or simultaneously adjusted while controlling the operation of the white light source unit 120. You can also choose to create it.
  • the narrowband light source unit 110 may directly generate narrowband light having a first wavelength using a light emitting diode (LED), the present invention is not necessarily limited thereto.
  • the light emitting device may include a wavelength converter 114 that receives light having the second wavelength and generates narrow band light having the first wavelength.
  • the narrowband light source unit 110 may be used a light emitting device that can provide incident light having a wavelength that can be determined according to the type of the wavelength conversion material used in the optical wavelength converter 114.
  • a light emitting device that can provide incident light having a wavelength that can be determined according to the type of the wavelength conversion material used in the optical wavelength converter 114.
  • QD quantum dot
  • light having a wavelength (eg, ultraviolet light) that can be used as incident light to the quantum dot is used.
  • a light emitting diode eg, an ultraviolet light emitting diode
  • a light emitting diode eg, an ultraviolet light emitting diode
  • the white light source unit 120 generates white light.
  • Various light emitting devices such as a white light emitting diode (LED) may be used as the white light source unit 116.
  • LED white light emitting diode
  • LEDs white light emitting diodes
  • whether the light emitting diodes (LEDs) emit light and light output (intensity) can be quickly adjusted through electrical control. While controlling the operation of the light source unit 110 together, it is also possible to generate a narrowband light image and a white light image simultaneously or at a time in real time.
  • a light emitting device such as a light emitting diode (LED) typically has a broader radiation angle, so that light is spread widely, and parallel light is emitted from the light emitting device.
  • a collimator made of a lens or the like may be used so as to be adjusted to a predetermined shape.
  • the light coupling unit 130 receives the light generated by the white light source unit 120 and the narrow band light source unit 110 and outputs the light to the light transmitting unit 140.
  • the light coupling unit 130 collects light incident from light sources separated from each other and outputs the light through the same output path.
  • the optical coupling unit 130 may be formed of a material capable of propagating light, such as glass, and collects light incident from the light sources separated from each other by using the refraction and reflection of the light to one output terminal. It has a structure to output.
  • FIG. 4 illustrates a structure having input ports separated from each other so as to correspond to light incident from the light sources separated from each other
  • the present invention is not necessarily limited thereto, and a trapezoidal structure as shown in FIG. 5 (a)), a structure having a lens-shaped curved surface at the input port side (FIG. 5 (b)), a trapezoidal structure having a lens-shaped curved surface at the input port side (FIG. 5 (c)), and the like. It can be implemented in various structures.
  • the optical coupling unit 130 may use a beam splitter or a dichroic mirror as shown in FIG. 6. It may also be implemented. As shown in FIG. 6, a part of the light irradiated from the narrow band light source unit 110 is reflected by the optical separator, but the other part passes through the optical separator and proceeds to the light transmitting unit 140, and also the white light source unit 120. Some of the light irradiated from the light) also passes through the optical splitter, but the rest of the light is reflected by the optical splitter to proceed to the light transmitting unit 140. The narrow band light and the white light are collected to collect the light transmitting unit 140. Will be output as
  • the light output from the optical coupling unit 130 may be focused and incident on the light transmitting unit 140.
  • a focusing lens may be provided.
  • the narrowband light source 110 and the white light source 120 generated from the narrowband light source unit 110 and the white light source unit 120 are separated from each other.
  • the narrow band light and the white light can be transferred and irradiated to the sample using only one light transmitting unit 140.
  • the light transmitting unit 140 be configured more compactly, but also manufacturing cost can be reduced.
  • the diameter of the endoscope may be greatly increased when the optical fiber is to be used separately corresponding to the narrow band light and the white light.
  • the optical coupling unit 130 may correspond to both the narrow band light and the white light using only one optical fiber, thereby greatly reducing the diameter of the endoscope.
  • the light transmitting unit 140 transmits the light output from the light coupling unit 130 to irradiate the sample.
  • the light transmitting unit 140 may be configured to include an optical fiber.
  • the light detector 150 may generate a narrow band light image and a white light image by detecting light reflected or emitted from the sample.
  • controller 160 may control whether light is generated in the narrow band light source unit 110 and the white light source unit 120.
  • the controller 160 may control to selectively generate light in one of the narrow band light source unit 110 and the white light source unit 120 at predetermined intervals.
  • the white light image generated by the white light and the The narrowband light source unit 110 and the white light source unit 120 may be simultaneously or selectively selected at a short periodic interval (for example, 5 to 30 times per second) to generate both narrowband images by narrowband light in real time.
  • the optical imaging apparatus 100 By controlling the light to be generated (in FIG. 4, narrow band light is generated and irradiated at time T1 and white light is generated and irradiated at time T2), the optical imaging apparatus 100 according to the present invention provides the white light image and the narrow band light.
  • the video can be provided simultaneously in real time.
  • the controller 160 controls to generate light simultaneously or selectively at the narrow-band light source unit 110 and the white light source unit 120 at short periodic intervals (for example, 5 to 30 or more times per second).
  • the optical imaging apparatus 100 By constructing an optical image through image processing of the white light image and the narrow band light image, the optical imaging apparatus 100 according to the present invention combines the white light image and the narrow band light image to obtain an optical image having improved contrast and other characteristics. You can also provide it.
  • the narrow band light source unit 110 receives the light emitting device 112 emitting light of the first wavelength and the light of the first wavelength. It may be configured to include a wavelength conversion unit 114 for converting into a narrow band of light of a different wavelength.
  • various light emitting devices such as a light emitting diode (LED) may be used as the light emitting device 112.
  • LED light emitting diode
  • the wavelength converter 114 may convert light of the first wavelength into narrow band light having a wavelength different from that of the first wavelength by using a quantum dot (QD), a phosphor, or the like. If the light can be converted into narrowband light having a wavelength different from the first wavelength can be used without particular limitation.
  • QD quantum dot
  • a phosphor a phosphor
  • the wavelength conversion unit 114 when the incident light ⁇ 1 having the first wavelength generated by the light emitting device 112 is irradiated to the wavelength conversion unit 114, the wavelength conversion unit 114 performs Various narrowband lights may be generated and output from the incident light ⁇ 1 of the first wavelength.
  • the light of the ultraviolet wavelength ⁇ 1 is generated in the light emitting element 112 (FIG. 7A).
  • the wavelength converter 114 is irradiated.
  • the wavelength converter 114 may convert the light having the ultraviolet wavelength into narrow band light having a specific wavelength ⁇ 2 required in the narrow band optical image (FIG. 7B) and output the narrow band light.
  • a quantum dot (QD) capable of converting the ultraviolet light into narrowband light having a wavelength of 415 nm or 540 nm corresponding to hemoglobin is used.
  • the wavelength conversion unit 114 can be configured.
  • the wavelength converter 114 may convert the light of the ultraviolet wavelength into narrowband light having a plurality of specific wavelengths ⁇ 2 and ⁇ 3 required in the narrowband light image (FIG. 7C) and output the light.
  • the wavelength conversion unit 114 may be configured to include the quantum dot QD corresponding to the 415 nm wavelength and the quantum dot QD corresponding to the 540 nm wavelength with respect to the narrowband endoscope image. And a narrowband light image that can correspond to both the 540nm wavelength.
  • the wavelength conversion unit 114 narrow-band light of the wavelength ⁇ 3 converted from the light of the first wavelength ⁇ 1 irradiated from the light emitting element 112 and the light of the first wavelength; It may also be released together (FIG. 7C).
  • the wavelength converter 114 When the light of the first wavelength ⁇ 1 is irradiated from the light emitting device 112 to the wavelength converter 114, the wavelength converter 114 absorbs light of the first wavelength and narrows the wavelength of another wavelength. The light is converted into backlight and is emitted. In this case, a part of the light of the first wavelength is converted into the wavelength converter 114 according to the concentration, thickness, etc. of the wavelength conversion material such as the quantum dot (QD) included in the wavelength converter 114. It may be transmitted through as it is. Accordingly, when it is necessary to block the light of the first wavelength, an optical filter unit (not shown) which blocks the light of the first wavelength and transmits the light of the other wavelength, if necessary, to the wavelength converter 114. May be further included.
  • QD quantum dot
  • the wavelength converter 114 converts the light of the first wavelength ⁇ 1 generated by the light emitting element 112 into narrow band light having a wavelength different from that of the first wavelength.
  • the wavelength conversion unit 114 is configured using a salping quantum dot (QD)
  • QD salping quantum dot
  • the narrowband light of various wavelengths may be generated by adjusting the size thereof, and thus may be conveniently applied to various applications in various fields such as medical and industrial.
  • FIG 8 illustrates the structure of the wavelength converter 114 in the optical imaging apparatus 100 according to the exemplary embodiment of the present invention.
  • the wavelength converter 114 is formed on the substrate 220 and the substrate 220 to convert light of the first wavelength into narrow-band light of another wavelength. It may be configured to include a light conversion layer 210.
  • the substrate 220 may be formed of a material through which narrow-band light of the other wavelength may pass.
  • the light conversion layer 210 may include a quantum dot (QD), a phosphor, etc. that can convert the light of the first wavelength into a narrow band light of a wavelength different from the first wavelength, in addition to the first Various materials may be used that may receive light of a wavelength and convert the light into a narrowband light having a wavelength different from that of the first wavelength.
  • QD quantum dot
  • a phosphor etc.
  • the wavelength conversion unit 114 in accordance with an embodiment of the present invention, but the light of the other wavelength is transmitted through the optical filter layer for filtering the light of the first wavelength 230 may be further provided. Accordingly, the wavelength converter 114 transmits light of another wavelength generated by receiving the light of the first wavelength from the light conversion layer 210, but blocks the light of the first wavelength. do.
  • the light conversion layer 210 is the optical filter layer without the use of the substrate 220 ( 230 may be formed on top. That is, the light conversion layer 210 may be formed on the optical filter layer 230 as the substrate 220. In this case, not only the light loss caused by the substrate 220 may be reduced, but also the structure of the wavelength converter 114 may be simplified to increase the manufacturing process efficiency and lower the manufacturing cost.
  • FIG. 9 is a flowchart illustrating an optical image generating method according to an embodiment of the present invention.
  • the optical image generating method a method for generating an optical image for the sample by irradiating a predetermined light to the sample, generating a narrow band light to generate a narrow band light Step S110, white light generation step of generating white light (S120), an optical coupling step (S130) of receiving the narrow band light and the white light and outputs the same output path, and transmits the narrow band light and white light to the sample
  • the optical image generating step (S160) of generating a white light image and a narrow band light image for the sample may be included.
  • optical image generating method is similar to the optical imaging apparatus 100 described above, and its operation principle and operation may be easily implemented and implemented by those skilled in the art. Reference may be made to a series of descriptions of the optical imaging apparatus 100.

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Abstract

La présente invention concerne un dispositif d'imagerie optique et un procédé de génération d'une image optique l'utilisant et, plus particulièrement, un dispositif d'imagerie optique qui génère une image optique à l'aide d'une source de lumière couplée comportant une partie de couplage de lumière qui couple la lumière générée dans une partie source de lumière blanche et la lumière générée dans une partie source de lumière à bande étroite et émet la lumière couplée, et un procédé de génération d'une image optique l'utilisant. L'invention concerne un dispositif d'imagerie optique qui envoie une lumière prédéterminée sur un échantillon, générant ainsi une image optique de l'échantillon, le dispositif d'imagerie optique étant caractérisé en ce qu'il comprend : une partie source de lumière à bande étroite qui génère de la lumière à bande étroite ; une partie source de lumière blanche qui génère de la lumière blanche ; une partie de couplage de lumière qui couple la lumière générée dans la partie source de lumière à bande étroite et la lumière générée dans la partie source de lumière blanche, et émet la lumière couplée ; une partie de transmission de lumière qui transmet la lumière émise par la partie de couplage de lumière et envoie la lumière sur l'échantillon ; et une partie de détection de lumière qui détecte la lumière réfléchie ou libérée par l'échantillon.
PCT/KR2017/013598 2016-12-20 2017-11-27 Dispositif d'imagerie optique pourvu d'une source de lumière couplée WO2018117451A1 (fr)

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KR20160174835 2016-12-20

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Citations (5)

* Cited by examiner, † Cited by third party
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KR20090030346A (ko) * 2006-08-18 2009-03-24 올림푸스 메디칼 시스템즈 가부시키가이샤 내시경 장치 및 그 신호 처리 방법
JP2013255655A (ja) * 2012-06-12 2013-12-26 Olympus Corp 撮像装置、顕微鏡装置、内視鏡装置
JP2014233344A (ja) * 2013-05-31 2014-12-15 Hoya株式会社 光学フィルタ素子、波長可変光バンドパスフィルタモジュール、波長可変光源装置及び分光内視鏡装置
JP2016154940A (ja) * 2016-05-26 2016-09-01 Hoya株式会社 内視鏡装置
JP2016187630A (ja) * 2016-07-29 2016-11-04 富士フイルム株式会社 内視鏡装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5371702B2 (ja) 2009-11-06 2013-12-18 富士フイルム株式会社 電子内視鏡システム、電子内視鏡用のプロセッサ装置、及び電子内視鏡システムの作動方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090030346A (ko) * 2006-08-18 2009-03-24 올림푸스 메디칼 시스템즈 가부시키가이샤 내시경 장치 및 그 신호 처리 방법
JP2013255655A (ja) * 2012-06-12 2013-12-26 Olympus Corp 撮像装置、顕微鏡装置、内視鏡装置
JP2014233344A (ja) * 2013-05-31 2014-12-15 Hoya株式会社 光学フィルタ素子、波長可変光バンドパスフィルタモジュール、波長可変光源装置及び分光内視鏡装置
JP2016154940A (ja) * 2016-05-26 2016-09-01 Hoya株式会社 内視鏡装置
JP2016187630A (ja) * 2016-07-29 2016-11-04 富士フイルム株式会社 内視鏡装置

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KR20180071956A (ko) 2018-06-28

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