WO2018056790A1 - Dispositif, procédé et programme d'entraînement de la mémoire par stimulation cérébrale - Google Patents

Dispositif, procédé et programme d'entraînement de la mémoire par stimulation cérébrale Download PDF

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Publication number
WO2018056790A1
WO2018056790A1 PCT/KR2017/010631 KR2017010631W WO2018056790A1 WO 2018056790 A1 WO2018056790 A1 WO 2018056790A1 KR 2017010631 W KR2017010631 W KR 2017010631W WO 2018056790 A1 WO2018056790 A1 WO 2018056790A1
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computer
response
user
memory
screen
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PCT/KR2017/010631
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English (en)
Korean (ko)
Inventor
강동화
김동호
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재단법인 아산사회복지재단
울산대학교 산학협력단
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Application filed by 재단법인 아산사회복지재단, 울산대학교 산학협력단 filed Critical 재단법인 아산사회복지재단
Priority to EP17853504.3A priority Critical patent/EP3517160B1/fr
Priority claimed from KR1020170123892A external-priority patent/KR101939339B1/ko
Publication of WO2018056790A1 publication Critical patent/WO2018056790A1/fr
Priority to US16/363,884 priority patent/US11376393B2/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis

Definitions

  • the present invention relates to a memory training apparatus, a method and a program, and more particularly, to a device, a method and a program for stimulating the brain to improve memory.
  • the present invention provides an apparatus and method for training spatial memory through brain stimulation that enhances the effect of improving spatial memory by simultaneously providing visual perception stimulation and spatial memory stimulation to a user's brain.
  • a computer provides a first problem on a task display unit within a screen, wherein the first problem is displayed on one or more output images at a specific position in the task display unit space. That is, the first problem providing step; A first response from the user to the computer, wherein the first response is a result of comparing the first problem provided before N times (N is a natural number) with the currently provided first problem Receiving step; And a response evaluation step of the computer evaluating the memory state of the user based on the first response.
  • the first problem providing step may include a computer measuring a gaze direction of a user and determining an arrangement position of an output image according to the first problem based on the gaze direction. It is done.
  • the first problem is provided by changing at least one of the number, type, arrangement position, and size of the output image, and the first response is N times the currently provided screen image. It is to input whether or not to match the previous screen image, wherein the screen image is the screen itself on which one or more output images are arranged according to the first problem.
  • the value of N is adjusted according to the user state.
  • the providing of the first problem may include determining a location in a three-dimensional space that displays an output image included in the first problem, based on a location in the three-dimensional space of the second problem. It is characterized by.
  • the computer provides a first problem on the screen of the head mounted display device.
  • the task display unit on the screen provides a first problem
  • the computer receives a first response to the first problem from the user
  • the computer Evaluate the memory state of the user based on the response, wherein the first problem is one or more output images are displayed at a specific position in the task display space, and the first response is the first problem provided N times and the currently provided The result of comparing the first problem.
  • the memory training program through brain stimulation is combined with a computer which is hardware to execute the above-mentioned memory training method through brain stimulation, and is stored in a medium.
  • a spatial memory stimulation and visual perception stimulation at the same time to the user's brain can improve the effect of improving spatial memory.
  • spatial memory when spatial memory is deteriorated due to brain damage or aging (for example, patients with dementia) or when spatial memory is insufficient due to normal growth, there is an effect of improving spatial memory through brain stimulation.
  • it when applied to growing children, it can provide an effect of improving the spatial memory of the child.
  • FIG. 1 is a flow chart of a memory training method through brain stimulation according to an embodiment of the present invention.
  • Figure 2 is a flow chart of the memory training method through the brain stimulation, further comprising a second problem providing and response process according to an embodiment of the present invention.
  • FIG. 3 is an exemplary diagram illustrating a process of performing memory training in accordance with a first problem according to an embodiment of the present invention.
  • Figure 4 is an internal configuration of the memory training apparatus through brain stimulation according to an embodiment of the present invention.
  • the 'computer' includes all the various devices capable of performing arithmetic processing.
  • a computer can be a desktop PC, a notebook, as well as a smartphone, a tablet PC, a cellular phone, a PCS phone (Personal Communication Service phone), synchronous / asynchronous
  • the mobile terminal of the International Mobile Telecommunication-2000 (IMT-2000), a Palm Personal Computer (PC), a Personal Digital Assistant (PDA), and the like may also be applicable.
  • the computer may also be a server computer that receives information from a client.
  • the 'first problem' refers to a problem provided on a screen in order to provide memory training to a user.
  • the "first problem” is a problem in which the user is requested to compare and judge the problem before N times.
  • the 'first response' means a response to a first problem provided at a specific time.
  • the 'second problem' refers to a problem provided to fix a user's gaze direction to a screen center.
  • the second problem may be to display any one of a plurality of objects (for example, ⁇ or ⁇ ) that is distinguished in the center of the screen at a specific time in the center of the screen.
  • the 'second response' refers to a response received from the user with respect to the second problem.
  • the 'output image' refers to an image provided at a specific position on the screen by the first problem.
  • the 'output image' may be a horizontal or vertical striped image displayed in a specific quadrant on the screen.
  • the 'screen image' is a screen itself on which one or more output images are arranged according to the first problem.
  • the screen image may be output to a general display device or to a head mounted display device.
  • the screen image may be generated as a left eye image and a right eye image, respectively.
  • the 'central field view part' means a central area within a screen provided to a user.
  • the 'near viewable part' refers to a remaining area of the screen except for the center viewable part.
  • a 'task display unit' refers to a region in which an output image which is a task of memory training is provided in a screen provided to a user.
  • the 'desk display unit' may include only the peripheral field of view except for the central field of view, or may include both the central field of view and the surrounding field of view.
  • FIG. 1 is a flow chart of a memory training method through brain stimulation according to an embodiment of the present invention.
  • a memory training method through brain stimulation may include: providing a first problem by a computer to a task display unit on a screen (S200; providing a first problem); Receiving, by the computer, a first response to the first problem from the user (S300; first response receiving step); And evaluating, by the computer, the memory state of the user based on the first response (S600; response evaluation step).
  • the computer provides a first problem to the task display unit on the screen (S200; a first problem providing step).
  • the first problem is that one or more output images are displayed at a specific position in the task display unit.
  • the first problem is provided by changing at least one of the number, type, arrangement position and size of the output image.
  • the first problem may be varied by changing the arrangement position of the output image included in the screen for each trial providing the first problem on the screen.
  • the computer may generate another screen image by changing the position on the screen where the same output image is displayed. Changing the position of the output image means that when the task display unit is divided into a plurality of divided regions, the divided region in which the output image of the first problem is displayed or a point where the output image is arranged in the same divided region is different. It may be.
  • the computer can generate various problem forms by changing the depth at which the output image is displayed.
  • the computer may display the output image by dividing it into an area near or far from the reference depth (eg, the depth at which the second problem is indicated when the second problem is provided).
  • the first problem providing step (S200) determines the position in the three-dimensional space for displaying the output image included in the first problem.
  • the images provided to the left and right eyes that is, the left eye image and the right eye image
  • the computer converges the left eye image and the right eye image with respect to the second problem while arranging the second problem to be described later at a specific depth, and arranges the output image according to the first problem at a specific depth to be disposed at the reference depth.
  • a screen in which the output image is displayed at various depths can be implemented.
  • the computer may change the type of the output image (for example, the classification of the figure and the character image, etc.) or the shape (for example, the horizontal stripe pattern and the vertical stripe pattern) to solve different first problems. Can be generated.
  • the computer may generate different problems by displaying output images of different shapes (for example, horizontal stripes and vertical stripes) at the same location of the task display unit.
  • the computer may create different first problems as the size of the output image is changed while displaying the same output image type / shape at the same location.
  • the computer receives a first response to the first problem from the user (S300; receiving a first response).
  • the first response is a result of comparing the first problem provided before N times (N is a natural number) with the currently provided first problem. For example, if N is 1, the computer compares the first first problem (ie, the screen image according to the previous first problem) with the current first problem (the screen image displayed on the current screen) from the user. The first response is received as a result of determining whether or not it is. Also, for example, if N is a specific natural number other than 1, the computer may receive from the user the result of comparing the current screen image with the screen image provided in the trial N times from the current trial as the first response of the current trial. Can be.
  • the computer evaluates the memory state of the user based on the first response (S600; response evaluation step). That is, when receiving a result of comparing the screen image with N times before as the first response, the computer compares the screen image with the previous N times and the current screen image stored therein to determine whether it is the same. To this end, in the case of performing spatial memory training in comparison with the previous N trials, the computer may store screen images of the N trials before. In addition, the computer may delete the screen image of the previous trial N times after comparison with the screen image of the current trial. When the first response input from the user is determined to be a correct answer, the computer may immediately inform the user that the answer is correct or increase the number of correct answers.
  • the computer may determine the memory state of the user based on the number of correct answers and adjust the difficulty of memory training. For example, if the memory training result at a specific N value of the user is good, the computer can increase the difficulty by increasing the N value of the memory training provided to the user at the next training. In other words, the computer can increase the difficulty of memory training by increasing the trial interval requiring the user to remember. Also, for example, the computer may increase the difficulty by lowering the brightness or saturation of the output image provided on the screen or reducing the size of the output image.
  • the computer may adjust the difficulty level by adjusting the number of output images appearing in the screen image. As the number of output images increases, the degree of difficulty may increase due to a complicated arrangement of output images. For example, in the case of providing horizontal stripes and vertical stripes as an output image, the computer may generate a screen image by providing a specific output image among horizontal stripes or vertical stripes to a part of the plurality of divided regions in the screen. The user has to compare whether the plurality of output image arrangement positions of the current trial and the types of output images displayed at each position are the same as the previous trial N times, thus providing a first problem having a higher difficulty level than when one output image is provided. Will receive.
  • the computer may determine whether any type of output image is memory based on the result of memory training of the patient. For example, memory may be degraded for an image displayed at a specific position within a viewing range according to a patient's condition, or memory for a specific shape may be degraded. Thus, the computer can determine the type of memory that the patient falls into based on the results of the brain stimulation training.
  • the screen image having a specific trial interval specific to the user that is, the current screen image and the previous screen image N times
  • the user should be made to visually recognize the screen image provided based on the first problem of the same condition.
  • the computer can apply various ways to provide the same screen image in each trial by the first problem of the same condition.
  • the computer may measure the user's gaze direction, determine the arrangement position of the output image according to the first problem based on the gaze direction can be provided.
  • the computer recognizes the user's bow movement or eye movement, acquires the gaze direction, and determines the arrangement position of the output image based on the gaze direction.
  • the computer measures the user's motion based on the motion data acquired through the motion sensor included in the head mounted display device.
  • the computer measures the eye movement based on eye movement data acquired by an eye movement sensor (ie, an eye tracker) included in the head mounted display device.
  • the computer calculates the visual direction (ie, the center direction of the visual field range) when the user's bow movement or eye movement is present.
  • the computer displays the output image about the visual direction (ie, the direction of the center of the viewing range) to generate the screen image provided for the particular trial.
  • the output image arrangement position information in the first problem is a relative position determined based on the visual direction (ie, the center direction of the viewing range), and the computer displays the screen image of each trial based on the output image arrangement position information in the first problem. Create Through this, the computer can smoothly provide memory training while the user performs free head movements and eye movements.
  • the computer provides a second problem displayed on the central field of view in the screen (S400; second problem providing step); And receiving a second response to the second problem (S500; receiving a second response).
  • the second problem serves to fix the gaze direction of the user at a specific position.
  • the second problem may be provided simultaneously with the first problem provided on one side of the task display unit. That is, a screen image for simultaneously displaying the first problem and the second problem on the screen is provided so that the user checks the first problem while the user watches the center view portion where the second problem is displayed. As the user looks at the central field of view where the second problem is displayed to input a correct answer to the second problem, the same condition of providing the screen image in the user's field of view may be formed.
  • the computer may accurately calculate the memory training result by excluding the first response inputted when the computer is not suitable to perform the response to the first problem.
  • the computer may determine whether the brain stimulation memory training is properly performed in a state where the gaze is fixed at the center of the screen based on the correct answer rate of the second problem displayed on the central field of view. For example, as the second problem is displayed in the small center of the screen, if the user does not accurately observe the central field of view where the second problem is displayed, the computer may set the correct answer rate to not be higher than a certain correct rate. It is determined whether the central fixation is properly performed. If the correct answer rate of the second response to the second problem is lower than the specified value, the computer may determine that the training is not performed properly and guide or re-perform the training.
  • FIG. 3 is a diagram for describing a method of training memory in a state in which a gaze direction of a user is fixed at a screen center based on a second problem according to an embodiment of the present invention.
  • the controller 130 displays the task display units 221 to 224 220 other than the center view 210 and the center view 210 as the memory training image 200. )
  • the central field of view 220 is a central area within the screen on which the problem 230 for fixing the user's gaze direction is displayed. That is, the central view unit 210 may include a predetermined problem (ie, a second problem) for fixing the focus of the user at the center.
  • the center view unit 210 may include a character or figure that can be guessed by the user, and the user may answer an answer corresponding to the character or figure included in the center view unit 210. 140).
  • the task display unit 220 is an area in which an output image to be compared with a previous trial is provided for the user's memory test.
  • the task display unit may divide the area in which the output image is displayed in various ways or numbers. For example, the task display unit 220 divides the virtual horizontal lines and the vertical lines based on the screen (ie, the memory training image) 200 as the quadrants into quadrants 221 to 224, and then divides the first quadrant into at least one quadrant. It may contain the output image according to the problem.
  • the first problem included in the task display unit 220 may be related to at least one of a spatial position, number, shape, and color of an output image (eg, a figure) displayed in at least one quadrant.
  • the computer can display the quadrant position at which the output image is provided, the position at which the output image is displayed within the quadrant, the type of the output image (for example, stripes or character images), and the shape of the output image (for example, horizontal stripes or vertical lines).
  • Various screens ie, memory training images
  • the computer outputs the screen image 220 including the central view 210 and the first problem 231 of the M-th point as the M-th training image 200.
  • the computer is the M + 1th training image 200 and the second problem provided to the central field of view 210 and the M + 1 time point provided to the task display unit 220.
  • the screen image 220 including one problem 232 is output.
  • the computer is provided with the second problem provided to the central field of view 210 as the M + Nth training image 200 and the M + N time point provided to the task display unit 220.
  • the screen image 220 including the first problem 232 is output.
  • the computer includes a first problem 231 in which the first problem 233 included in the M + N th training image 200 is included in the training image 200 before M times.
  • the user's answer regarding whether or not may be received through the user input unit 140. That is, the computer receives a response from the user as to whether the screen image according to the first problem at the Nth point and the screen image according to the first problem at the M + N point coincide.
  • the user may include a spatial position (eg, a specific position in a specific quadrant) of the figure included in the first problem 233 included in the M + N th training image 200, a shape of the figure, and a shape of the figure. If the number, the size of the figure, the color of the figure, etc. match the first problem 231 included in the N-th training image 200, O may be input. If one does not match, X may be input.
  • the user may input an answer as to whether the N-th training image 200 corresponds to a problem included in the previous image, and FIG. 3B.
  • the user's answer may be input as to whether or not a match with a problem included in a previous image of a specific number of times of the M + 1 th training image 200 is obtained.
  • the user can improve the short-term and medium-long term memory through repetitive training, which remembers the problems contained in the task display part of the training image before a certain number of times and compares the problems included in the task display part of the current training image.
  • the spatial memory can be trained by storing the position of the output image provided in the screen image.
  • the hippocampus of the brain is in charge of spatial memory, and the recovery of function by stimulating the hippocampus by brain connectivity only with visual perceptual learning training (ie, training to provide a visual stimulus to the patient). It is possible. Accordingly, the present invention provides the effect of increasing visual memory stimulation speed by repeatedly providing visual perception stimuli to the eye and training to remember spatial arrangement in order to improve hippocampus function in charge of spatial memory. do.
  • the present invention is a brain region (for example, primary visual domain, parietal lobe, frontal lobe) that performs the Egocentric (sensory receptor center) processing of space-time and space-time environment allocentric (space-time environment itself)
  • a brain region for example, primary visual domain, parietal lobe, frontal lobe
  • Egocentric sensor receptor center
  • space-time and space-time environment allocentric space-time environment itself
  • FIG. 4 is an internal configuration diagram of a memory training apparatus through brain stimulation according to an embodiment of the present invention.
  • the memory training apparatus 100 may include all or a portion of the display 110, the memory 120, the controller 130, and the user input unit 140.
  • the memory training apparatus 100 may be a computer, a personal computer, a display device, a portable terminal, or the like, but is not limited thereto.
  • the memory training device 100 is a device for training spatial memory by visually stimulating a user's brain.
  • the spatial memory power may mean a memory power for a spatial position, a shape, and the like of a visual display (for example, a figure) appearing in front of the visual field.
  • the memory 120 stores a memory training program.
  • the memory training program may be a native program pre-installed in the memory training apparatus 100 or a program downloaded and installed from an external server.
  • the memory 120 may be an external memory connected to or inserted into the memory training apparatus 100.
  • the controller 130 may output a training image corresponding to the visual perception training program to the display 110.
  • the training image may include a task display unit for fixing the focus of the user to the center.
  • the task display unit may include a predetermined problem (ie, a first problem) for training the spatial memory of the user. That is, the task display unit displays the output image according to the first problem at a specific position in a two-dimensional or three-dimensional space.
  • the task display unit may use only the peripheral field of view, or may use both the peripheral field of view and the central field of view.
  • the first problem may be performed on the task display unit in various ways.
  • the output image (eg, figure) of the first problem may be displayed in a specific quadrant among the four divided quadrants of the task display unit, and the placement position in the specific quadrant, the shape, size, and color of the output image. At least one can be adjusted.
  • the user input unit 140 may receive a user input related to the memory training image.
  • the user may input a response corresponding to a problem included in the central view field unit and a problem included in the task display unit through the user input unit 140.
  • the controller 130 outputs the task display unit including the center view portion and the first problem as the M-th training image to the display 110, and the task including the center view portion and the second problem as the M + N-th training image.
  • the display unit may be output to the display 110 and the user input unit may answer the user's answer as to whether the second problem included in the M + Nth training image matches the first problem included in the training image before N times. 140). That is, the controller 130 determines whether the answer is correct by receiving a first response, which is a result of comparing the first problem provided N times and the currently provided first problem, from the user through the user input unit 140.
  • the controller 130 may adjust the difficulty level of the problem included in the task display unit based on the correct answer rate of the answer input through the user input unit 140.
  • the difficulty of the problem included in the task display unit may be adjusted by adjusting the number of N or adjusting at least one of the number, shape, and color of the figure displayed in the task display unit.
  • the controller 130 provides a second problem for fixing the user's gaze direction to the center of the screen in the center view portion of the display 110.
  • the second problem is a predetermined problem for focusing the user's attention so that the user's focus is fixed at the center.
  • the controller 130 may use only the peripheral view portion as a task display unit that provides the first problem so that the first problem and the second problem do not overlap.
  • the memory training method through brain stimulation according to an embodiment of the present invention described above may be implemented as a program (or application) to be executed in combination with a computer which is hardware and stored in a medium.
  • the memory training program through brain stimulation may be directly installed in a device that outputs a screen (that is, a device having a display unit) or may be installed in a device connected to the display device.
  • a device that outputs a screen that is, a device having a display unit
  • the head mounted display device may be installed in a mobile terminal (for example, a smartphone or a PC) to which the head mounted display device is connected, and has a processor capable of arithmetic processing.
  • One head mounted display device may install a memory training program through brain stimulation.
  • the above-described program includes C, C ++, JAVA, machine language, etc. which can be read by the computer's processor (CPU) through the computer's device interface so that the computer reads the program and executes the methods implemented as the program.
  • Code may be coded in the computer language of. Such code may include functional code associated with a function or the like that defines the necessary functions for executing the methods, and includes control procedures related to execution procedures necessary for the computer's processor to execute the functions according to a predetermined procedure. can do.
  • the code may further include memory reference code for additional information or media required for the computer's processor to execute the functions at which location (address address) of the computer's internal or external memory should be referenced. have.
  • the code may be used to communicate with any other computer or server remotely using the communication module of the computer. It may further include a communication related code for whether to communicate, what information or media should be transmitted and received during communication.
  • the stored medium is not a medium for storing data for a short time such as a register, a cache, a memory, but semi-permanently, and means a medium that can be read by the device.
  • examples of the storage medium include, but are not limited to, a ROM, a RAM, a CD-ROM, a magnetic tape, a floppy disk, an optical data storage device, and the like. That is, the program may be stored in various recording media on various servers to which the computer can access or various recording media on the computer of the user. The media may also be distributed over network coupled computer systems so that the computer readable code is stored in a distributed fashion.

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Abstract

La présente invention concerne un dispositif, un procédé et un programme d'entraînement de la mémoire par stimulation cérébrale. Le procédé d'entraînement de la mémoire par stimulation cérébrale, selon un mode de réalisation de la présente invention, comprend : une étape de présentation d'un premier problème (S200) dans lequel un ordinateur présente un premier problème dans une zone d'affichage de tâche d'un écran, le premier problème étant constitué d'une ou de plusieurs images de sortie affichées dans une position prédéterminée à l'intérieur de la zone d'affichage de tâche ; une première étape de réception de réponse (S300) dans laquelle l'ordinateur reçoit, d'un utilisateur, une première réponse au premier problème, la première réponse étant un résultat de la comparaison d'un premier problème présenté avant ou à un Nième moment (N étant un nombre naturel) avec le premier problème actuellement présenté ; et une étape d'évaluation de réponse (S600) dans laquelle l'ordinateur évalue l'état de mémoire de l'utilisateur sur la base de la première réponse.
PCT/KR2017/010631 2016-09-26 2017-09-26 Dispositif, procédé et programme d'entraînement de la mémoire par stimulation cérébrale WO2018056790A1 (fr)

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US16/363,884 US11376393B2 (en) 2016-09-26 2019-03-25 Device and method for training memory using brain stimulation

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KR1020170123892A KR101939339B1 (ko) 2016-09-26 2017-09-26 뇌 자극을 통한 기억력 훈련 장치, 방법 및 프로그램
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Cited By (2)

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Publication number Priority date Publication date Assignee Title
CN109300364A (zh) * 2018-11-30 2019-02-01 北京京师脑力科技有限公司 一种提高记忆力的认知训练方法及系统
CN115188447A (zh) * 2022-09-08 2022-10-14 浙江强脑科技有限公司 一种基于脑电信号的记忆力训练方法和训练装置

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