WO2018049461A1 - Pompe nasogastrique - Google Patents

Pompe nasogastrique Download PDF

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Publication number
WO2018049461A1
WO2018049461A1 PCT/AU2017/000183 AU2017000183W WO2018049461A1 WO 2018049461 A1 WO2018049461 A1 WO 2018049461A1 AU 2017000183 W AU2017000183 W AU 2017000183W WO 2018049461 A1 WO2018049461 A1 WO 2018049461A1
Authority
WO
WIPO (PCT)
Prior art keywords
pump
nasogastric
patient
way valve
tube
Prior art date
Application number
PCT/AU2017/000183
Other languages
English (en)
Other versions
WO2018049461A9 (fr
Inventor
John Cartmill
David Inglis
Aaron Kelly
Bert Christian Acojido GALASINAO
Original Assignee
Macquarie University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2016903689A external-priority patent/AU2016903689A0/en
Application filed by Macquarie University filed Critical Macquarie University
Publication of WO2018049461A1 publication Critical patent/WO2018049461A1/fr
Publication of WO2018049461A9 publication Critical patent/WO2018049461A9/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/80—Suction pumps
    • A61M1/82—Membrane pumps, e.g. bulbs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1042—Alimentary tract
    • A61M2210/1053—Stomach

Definitions

  • the invention relates to a nasogastric pump for the extraction of fluid from the stomach of a patient and to a method of extracting fluid from the stomach of a patient.
  • Nasogastric intubation is a well-known method of removing fluids from the stomach or small intestine of a patient by inserting an elongate tube through the patient's nose, through the patient's oesophagus and into the stomach. Suction is then applied to the tube to drain the stomach contents upwardly through the tube and out of the patient.
  • Nasogastric intubation is commonly used in situations in which it is required to drain the stomach contents, for example prior to gastrointestinal operations, to obtain a sample of the gastric contents for analysis, to remove toxic substances or to flush the stomach during gastrointestinal bleeding or poisoning.
  • Prolonged nasogastric intubation is also used to maintain an empty stomach and rest the intestine, for example, following abdominal surgery or obstruction.
  • the intubation procedure is a traumatic and often painful experience for patients.
  • the nasogastric tube is formed of a material that must be rigid enough to sustain the vacuum pressures applied to the tube to draw the stomach contents therethrough.
  • the insertion of the rigid tube through the patient's nose in itself causes discomfort and anxiety in patients.
  • the tube when worn for sustained periods, the tube may also cause sinusitis, infections and ulcerations to the pharynx and oesophagus. Discomfort due to sustained usage is difficult to avoid.
  • a nasogastric pump for the extraction of fluid from the stomach of a patient
  • the nasogastric pump comprising: an elongate tube adapted for placement through the nasal cavity of a patient and into the stomach of the patient such that a distal end thereof is disposed in the stomach of the patient; and a pump apparatus housed within the distal end of the tube, the pump apparatus being adapted to admit fluid therein from the stomach of the patient and to positively displace fluid from the pump apparatus towards a proximal end of the tube.
  • the nasogastric pump can reside inside the patient's stomach during nasogastric intubation and works under the application of positive pressure rather than suction to extract fluid from the stomach of a patient. Since the pump apparatus operates under positive pressure, the need for the application of vacuum pressure to the nasogastric tube is removed, allowing the tube to be far less rigid. The tube can be soft and even flaccid.
  • the tube is made of a compliant material, for example silicone.
  • a compliant material greatly reduces the di scomfort of the patient during the intubation process and significantly reduces the possibility of ulceration, irritation and discomfort of the pharynx and oesophagus.
  • the pump apparatus comprises a first one-way valve disposed inside the distal end of the tube and a second one-way valve disposed inside the distal end of the tube in spaced relation with the first one-way valve so as to define a chamber therebetween; wherein the first one-way valve is adapted to admit fluid from the stomach of the patient into the chamber and the second one-way valve is adapted to release fluid from the chamber towards the proximal end of the tube; and a pump element disposed inside the chamber between the first one way valve and the second one-way valve, the pump element being actuatable from a first condition in which the chamber has a first volume to a second condition in which the chamber has a second decreased volume to cause fluid within the chamber to be released through the second one-way valve, and to revert from the second condition to the first condition to cause the admission of fluid from the stomach of the patient through the first one way valve and into the chamber.
  • the pump element is a bladder, preferably made of latex.
  • the bladder is an unexpanded form and under the second condition it is in an expanded form.
  • a positive pressure source is provided for cyclically actuating the bladder.
  • the positive pressure source is configured to remotely provide cyclic positive pressure to the bladder from a location external to the patient.
  • the positive pressure source is an external compressed air supply.
  • the bladder is actuated by a positive pressure source in the form of an electromechnical material disposed within the chamber and being actuatable from a location external to the nasogastric pump to apply positive pressure to the bladder.
  • the electromechnical material is a piezoelectric or electro-active material, such as poly vinylidene fluoride and carbon nanotube composites
  • the positive pressure source comprises motion of an electromagnetic material associated with the pump element, the motion being actuated by an external magnetic field.
  • the pump element is a solenoid actuated spring associated with the first one way valve and adapted for moving the first one-way valve from an initial position in which the spring and the first one-way valve are in the first condition to an actuated position in which the spring and the one-way valve are in the second condition, the spring being biased to return the first one way valve to the initial position in the absence of solenoid actuation.
  • each of the first one way valve and the second one-way valve comprises a membrane check valve.
  • the nasogastric pump further includes an insert guide adapted for guiding the tube through the nasal cavity of the patient where otherwise the flexibi lity of the compliant tube may prevent this from occurring.
  • the insert guide is a short length of wire or ri gid material, suitable for performing the task whilst minimising discomfort to the patient.
  • the pump apparatus includes a motor driven centrifugal pump or Archimedes scroll or helical pump. These embodiments do not require a volume change in order to operate and may not require valves.
  • a method of extracting fluid from the stomach of a patient comprising: intubating the patient with a nasogastric pump as described above; and actuating the pump apparatus of the nasogastric pump to admit fluid therein from the stomach of the patient and to positively displace fluid from the pump apparatus towards a proximal end of the tube.
  • Figure 1 shows a schematic representation of a nasogastric pump insitu inside a patient
  • Figure 2 shows a first embodiment of a nasogastric pump in accordance with the invention
  • Figure 3a is an enlarged schematic side view of the pump apparatus of the nasogastric pump of Figure 2;
  • Figure 3b is a bottom view of the pump apparatus of Figure 3a;
  • Figure 4a is an enlarged front view of the pump apparatus of the nasogastric pump of Figures 2 and 3;
  • Figure 4b is a top view of the pump apparatus of Figure 4a;
  • Figure 5a shows an upper valve member of one embodiment of the one way valve
  • Figure 5b shows a lower valve member of the embodiment of the one way valve of Figure 5 a
  • Figure 5c shows an assembled one way valve including the valve members of Figure 5a and Figure 5b;
  • Figure 6 is a schematic representation of a second embodiment of a nasogastric pump in which the pump element is actuatable by the motion of an electromagnetic material
  • Figure 7 is a schematic representation of a third embodiment of a nasogastric pump in which the pump element is actuatable by the bending of an electro-active material
  • Figure 8 is a schematic representation of a fourth embodiment of a nasogastric pump in which the pump element is actuatable by a piezoelectric material;
  • Figure 9a is a schematic of a fifth embodiment of a nasogastric pump operated by a solenoid in an initial configuration
  • Figure 9b is a schematic of the embodiment of Figure 9a in an actuated configuration
  • Figure 10 is a sixth embodiment of a nasogastric pump in which an electric motor is used to drive a centrifugal pump;
  • Figure 1 1 is a seventh embodiment of a nasogastric pump in which an electric motor is used to drive a helical pump;
  • Figure 12(a)-(d) are schematic representations of examples of valve types that may be used in at least the embodiments of Figures 1 to 9b.
  • Figure 1 shows a schematic representation of a nasogastric pump 1 positioned in situ in a patient.
  • the nasogastric pump 1 comprises an elongate tube 5 having a distal end 10 that is inserted through the nasal cavity 15 of the patient, through the oesophagus 12 and into the stomach 20.
  • a proximal end 30 of the tube 5 remains uninserted through the nasal cavity 15, outside of the patient's body.
  • the tube 5 is of approximately 4 mm outer diameter and is made of a compliant material such as silicone.
  • the distal end 10 of the tube 5 houses a pump apparatus 40 therein.
  • the pump apparatus 40 comprises of a first one-way valve 60 and a second one-way valve 50 disposed in spaced relation with one another inside the distal end 10 of the tube 5 so as to define an elongate chamber 65 there between.
  • the chamber 65 must be semi-rigid such that it can sustain a small negative pressure without collapsing.
  • the one-way valves 50, 60 are configured to permit fluid flow therethrough in one direction only under certain conditions that will be described in detail below. Otherwise, the one-way valves 50, 60 create a barrier to fluid flow therethrough.
  • a pump element 70 in the form of a bladder 70 or other expandable or inflatable element lies inside the chamber 65.
  • the bladder 70 is made of latex rubber and is attached at an open proximal end thereof to a narrow supply tube 75 that extends through the tube 5 and out of the proximal end 30 thereof for connection to a supply of compressed air 80.
  • the supply tube 75 has an outer diameter of about 1-2 mm and bypasses the second one way valve 50 using a short length of needle-gauge tubing (not shown for clarity) so that the supply tube 75 can provide compressed air from the compressed air supply to the bladder 70 regardless of whether the second one way valve 50 is open.
  • the one-way valves 50, 60 each comprise of a membrane check valve.
  • the valves are identical to one another and will be described with regard to the second one way valve 50, it being understood that the first one-way valve 60 includes the same features and operates in the same manner.
  • the one-way valve 50 includes an upper valve member 51 (see Figure 5a) and a lower valve member 52 (see Figure 5b) and a membrane 53 (seen in Figures 3a-4b) disposed between the two.
  • the lower valve member 52 is a cylindrical member made of steel and having a side wall sized to fit closely within the tube 5 with a sealing fit.
  • the lower valve member 52 includes a pair of conduits 54 extending from a distal end 55 of the lower valve member, through to a proximal end 56 thereof.
  • the proximal end 56 has a shallow recessed stepped portion 57 for receiving a distal end 82 of the upper valve member 51 thereon.
  • the membrane 53 is a circular membrane made of an elastomeric or stretchy rubberlike substance such as natural rubber or silicone rubber. The membrane 53 sits atop the proximal end 56 of the lower valve member 52 so as to cover the pair of conduits 54 and has the same diameter as the recessed proximal end 56.
  • the upper valve member 51 is also cylindrical and made of steel, having a sidewall sized to fit closely within the tube 5 with a sealing fit.
  • FIG. 52 shows the assembled valve 60.
  • the assembled valve 60 is identical to the assembled valve 50.
  • the valve 50 (and therefore also the valve 60) operates as follows. Under normal ambient pressure, the valve remains closed to the flow of fluid therethrough since pressure forces acting on the valve 50 equal the tension forces acting thereon. However, if a sufficient pressure differential is established upstream of the membrane 53 (or downstream of the membrane of the val ve 60), the membrane 53 moves to open the valve 50 to the passage of fluid flow therethrough. As the pressure differential equates again, the membrane 53 moves again to close the valve 50.
  • Operation of the first embodiment of the nasogastric pump 1 is as follows.
  • the compressed air supply 80 is controlled by a controller (not shown) to provide compressed air through the supply tube 75 and into the bladder 70.
  • the compressed air is supplied to the bladder cyclically so as to expand and relax the bladder 70 according to a desired time cycle.
  • the input of compressed air into the bladder 70 causes it to inflate and expand in size within the tube 5 such that the volume within the chamber 65 decreases and the internal pressure within the chamber 65 increases correspondingly.
  • the membrane 53 moves to open the valve 50.
  • the bladder 70 continues to expand, pushing most of fluid in the chamber 65 towards the proximal end 30 of the tube 5.
  • the release of compressed air from the bladder 70 causes it to relax back to its initial unexpanded condition, increasing the volume in the chamber 65 and correspondingly lowering the pressure inside the chamber 65.
  • the low pressure within the chamber 65 causes the membrane in the first one way valve 60 to open, drawing fluid from the stomach into the distal end 10 of the tube 5 and into the chamber 65 of the pump 40, where it resides until the second valve 50 reopens.
  • a method of extracting fluid from the stomach of a patient comprises intubating the patient with the nasogastric pump 1.
  • the tube 5 and pump apparatus 40 may be advanced through the nasal cavity 15 and the oesophagus 12 without any further guidance being required.
  • an insert guide 90 shown schematically in Figure 1 and comprising a short length of wire or other suitable rigid material is placed into the nasal cavity 15 alongside the tube 5 for guiding the distal end 10 of the tube through the nasal cavity 15. The insert guide 90 can then be discarded.
  • the compressed air supply 80 can be actuated to apply a positive pressure through the supply tube 75 and into the bladder 70 to operate/actuate the pump apparatus 40 to extract the fluid from the stomach, into the oesophagus 12 and upwardly through the tube 5 and out of the patient.
  • the use of the positive displacement pump 40 within the nasogastric tube 5 provides an efficient means of draining the stomach contents without subjecting the patient to the sustained placing of rigid tubing inside the nasal cavity 15 and oesophagus 12, leading to reduced suffering, improved recovery times and the consequent economic benefits of the patient requiring a shorter stay in hospital.
  • a positive pressure source may not necessarily comprise a compressed air supply and may take other forms.
  • an electromagnet or piece of piezoelectric or electro active material can be placed adjacent to the bladder 70 or other suitable expandable or moveable pump element to cause it to decrease the volume within the chamber 65 and to increase the pressure within the chamber 65 in order to operate the valve 50.
  • the pump element 170 comprises of a latex tube inside the chamber 165, the latex tube being attached to an interior of the di stal end 110 of the elongate tube 105 at each end 1 1 1, 1 12 thereof, between the one way valves 150, 160.
  • the central part of the latex tube is unattached to the elongate tube 105 and is free to laterally move as depicted by the arrows 175 shown in Figure 6.
  • the interior of the latex tube 170 effectively describes the chamber 165 of the pump apparatus.
  • the pump apparatus further includes at least a pair of ferromagnetic elements 180 arranged at a position on the latex tube wall that is approximately mid-way between one-way valves 150, 160.
  • An externally located electromagnet 190 placed above or below the patient's abdomen, is actuatable by an automated electronic switch to move the ferromagnetic material elements 180 of the pump laterally to cyclically compress the pump element wall 170 laterally to a condition in which the volume inside the chamber 165 is reduced and then to release the latex tube wall to return it to its initial condition in which the initial volume inside the chamber 165 is reinstated.
  • the change in volume of the chamber 165 causes fluid to flow through the one-way valves 150, 160 as in the first embodiment, but the change in volume of the chamber 165 is effected via electromagnetic actuation.
  • the pump element 270 comprises of a tube of electro-active material such as PVDF composite that is attached to an interior of the distal end 210 of the elongate tube 205 at each end 21 1, 212 thereof, between the one-way valves 250, 260.
  • the central part of the tube of electro active material 270 is unattached to the elongate tube 205 and is free to laterally move as depicted by the arrows 275 shown in Figure 7.
  • the interior of the electro-active material tube 270 effectively describes the chamber 265 of the pump apparatus.
  • the electro-active material 270 is actuated by an externally located battery 290 which is electrically connected to the electro-active material 270 by a pair of wires 287, 288.
  • Actuation causes the electro -active material 270 to bend.
  • the portion of the electro-active material tube 270 that is free to move bends laterally inwardly to a condition in which the volume inside the chamber 265 is reduced. If the electric current is then removed from the electro-acti ve material tube 270, the electro- active material reverts to its initial, unbent, condition, reinstating the initial volume of the chamber 265.
  • the change in volume of the chamber 265 causes fluid to flow through the one-way valves 250, 260 as in the first embodiment, but the change in volume is effected via electric actuation of the electro-active material.
  • the pump apparatus comprises of one-way valves 350, 360 that are operable as in the previous embodiments and a piezoelectric tube 370 forming a chamber 365 arranged between the one-way valves 350, 360 , the piezoelectric tube 370 being compressed and elongated (as depicted by the arrows 375) by the axial strain of piezoelectric or electro-active materials, typically a layered stack of piezo electric (or electroactive) polymers.
  • the electro- active materials 370 are actuated by an external battery 390 via connecting wires 387, 388.
  • the pump apparatus may take a different form from the embodiments of Figures 1 to 8 described above. Possible variations on the pump apparatus are shown in Figures 9a - 1 1 and are described below.
  • the method of use of each of the nasogastric pumps described herein is the same as has been described in respect of the nasogastric pump 1 , notwithstanding the different pump apparatus and sources of positive pressure that are used in each embodiment.
  • the pump apparatus comprises of one-way valves 450, 460 that are operable as in the previous embodiments.
  • the proximal one-way valve 450 is fabricated from ferromagnetic steel and can be moved from an initial position within the distal end of the elongate tube 405 as shown in Figure 9a, to an actuated position that is closer to the distal one-way valve 460 as shown in Figure 9b, to reduce the length, and therefore volume, of the chamber 465.
  • the one-way val ve 450 is then returned to its initial position to reinstate the initial length and volume of the chamber 465.
  • the one way valve 450 is actuated between its initial and actuated positions by a solenoid 480 that is electrically powered by an external battery 490.
  • a pair of wires 487, 488 connects the battery 490 to the solenoid 480.
  • the solenoid 480 is also connected to the one-way valve 450 such that actuation of the solenoid 480 pulls the one-way valve 450 downwards to its actuated position, decreasing the volume of the chamber 465.
  • the pump apparatus also includes a spring 495 that is engaged with the proximal one-way valve 450 and which is biased to push the proximal one-way valve 450 back into its initial position to reinstate the initial volume of the chamber 465 when no electrical power is provided to the solenoid 480.
  • the pump apparatus is a centrifugal pump 580 that is driven by a rotary motor 585a, 585b, as shown schematically in Figure 10.
  • the centrifugal pump 580 is positioned inside the distal end of the elongate tube 505 and secured therein by e.g. a suitable glue.
  • the motor includes a rotor 585a and a stator 585b at the centre of the centrifugal pump 580.
  • the motor 585a, 585b of the centrifugal pump 580 is connected by two wires 587, 588 to an externally located battery 590.
  • the centrifugal pump 580 is operable to draw fluid from the stomach and into the centre of the centrifugal pump 580, from where it is pumped radially outwardly by centrifugal force and positively displaced towards the proximal end of the elongate tube 505 and out of the nasogastric pump.
  • This embodiment does not require any one-way valves in order to operate.
  • the inclusion of one-way valves, one at either end of the pump apparatus as in the previous embodiments, may allow the pump to be switched off or to be operated cyclically without fluid therein flowing back out of the nasogastric pump and into the stomach.
  • the centrifugal pump is replaced by an Archimedes screw or helical pump 680.
  • the helical pump 680 is positioned inside the distal end of the elongate tube 605 and is driven by a motor 685 a, 685b that is connected by two wires 687, 688 to an externally located battery 690.
  • the helical pump includes a rotating central helical screw 680 housed inside a static cylindrical housing that is securable inside the tube 605 using glue or other suitable securing means.
  • the helical screw is driven by a motor comprising of a rotor 685a and stator 685b.
  • Upper and lower mounts 686 are secured within the tube 605 and connected to the rotor 685a to prevent movement of the rotor during use of the helical pump 680.
  • the helical pump 680 is operable to draw fluid from the stomach and into the helix of the helical pump 680, from where it is pumped upwardly by rotation of the helical pump 680 and positively displaced towards the proximal end of the elongate tube 605 and out of the nasogastric pump.
  • This embodiment does not require any one-way valves in order to operate. However, the inclusion of one-way valves, one at either end of the pump apparatus as in the previous embodiments, may allow the pump to be switched off or to be operated cyclically without fluid therein flowing back out of the nasogastric pump and into the stomach.
  • valves 12 a and 12b respectively.
  • the membrane 701 has a circular shaped circumference and held onto the valve seat 703 at two attachment points 705, 710 located at opposite ends of the membrane.
  • the membrane 701 is designed to lift a way from the valve seat along the circumference either side of the two attachment points 705, 710.
  • the membrane 801 is attached to the circular valve seat 803 along one side of the tube that is common with a circumference of the circular val ve seat 803, such that the membrane lifts asymmetrically along the free edges of the membrane 801.
  • FIGs 12c- 12d Further examples of possible membrane valve designs are shown in Figures 12c- 12d.
  • the valve opens in a three dimensional cruciform shape, whilst in Figure 12 d the valve opens three dimensionally along a central slit.
  • timing cycles can be employed for the expansion and contraction of the pump element 70 (in the form of a bladder) or the movement of the pump element 270 (electro-active material tube), 370 (piezo electric stack), or upper one-way valve 450 and that a wide range of pressures can be employed, depending on the geometry of the pump element.
  • a typical operating pump may require one to two atmospheres of pressure to be applied at a rate of one cycle per second.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

L'invention concerne une pompe nasogastrique pour l'extraction de fluide à partir de l'estomac d'un patient. La pompe nasogastrique comprend un tube allongé et un appareil de pompage. Le tube allongé est conçu pour être placé à travers la cavité nasale d'un patient et dans l'estomac du patient de telle sorte qu'une extrémité distale de celui-ci est disposée dans l'estomac du patient. L'appareil de pompage est logé à l'intérieur de l'extrémité distale du tube. L'appareil de pompage est conçu pour admettre un fluide à l'intérieur de l'estomac du patient et pour déplacer positivement le fluide de l'appareil de pompage vers une extrémité proximale du tube.
PCT/AU2017/000183 2016-09-14 2017-09-05 Pompe nasogastrique WO2018049461A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2016903689 2016-09-14
AU2016903689A AU2016903689A0 (en) 2016-09-14 Nasogastric pump

Publications (2)

Publication Number Publication Date
WO2018049461A1 true WO2018049461A1 (fr) 2018-03-22
WO2018049461A9 WO2018049461A9 (fr) 2018-06-07

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PCT/AU2017/000183 WO2018049461A1 (fr) 2016-09-14 2017-09-05 Pompe nasogastrique

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108421148A (zh) * 2018-04-13 2018-08-21 汕头市中心医院 一种省力防脱自动正压封闭的胃管供给器
CN113289198A (zh) * 2021-04-16 2021-08-24 杭州未名信科科技有限公司 给药导管和给药导管的制备方法

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3689204A (en) * 1970-05-18 1972-09-05 Gen Motors Corp Laminated liquid pump and method of making same
US5643230A (en) * 1995-05-15 1997-07-01 Linder; Gerald Seymour Nasogastric suction catheter
US20030187322A1 (en) * 2000-08-18 2003-10-02 Thorsten Siess Intracardiac blood pump
US20050277900A1 (en) * 2002-11-04 2005-12-15 Samuel Klein Apparatus for treating obesity by extracting food
US20120191038A1 (en) * 2006-10-10 2012-07-26 Allen Gerber Retrofittable aspiration prevention mechanism for patients
US20130006323A1 (en) * 2011-06-27 2013-01-03 E-Motion Medical, Ltd. Esophageal stimulation devices and methods
US20140276633A1 (en) * 2013-03-15 2014-09-18 Nadarasa Visveshwara Fluid and nutrition delivery device and method of use
US20150209239A1 (en) * 2012-08-17 2015-07-30 Chris Salvino Nasogastric tube
WO2015193880A1 (fr) * 2014-06-15 2015-12-23 Yair Feld Dialyse péritonéale implantable continue
WO2016040444A1 (fr) * 2014-09-09 2016-03-17 Baylor Research Institute Tubes intraluminaux avec des structures déployables et procédés associés

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3689204A (en) * 1970-05-18 1972-09-05 Gen Motors Corp Laminated liquid pump and method of making same
US5643230A (en) * 1995-05-15 1997-07-01 Linder; Gerald Seymour Nasogastric suction catheter
US20030187322A1 (en) * 2000-08-18 2003-10-02 Thorsten Siess Intracardiac blood pump
US20050277900A1 (en) * 2002-11-04 2005-12-15 Samuel Klein Apparatus for treating obesity by extracting food
US20120191038A1 (en) * 2006-10-10 2012-07-26 Allen Gerber Retrofittable aspiration prevention mechanism for patients
US20130006323A1 (en) * 2011-06-27 2013-01-03 E-Motion Medical, Ltd. Esophageal stimulation devices and methods
US20150209239A1 (en) * 2012-08-17 2015-07-30 Chris Salvino Nasogastric tube
US20140276633A1 (en) * 2013-03-15 2014-09-18 Nadarasa Visveshwara Fluid and nutrition delivery device and method of use
WO2015193880A1 (fr) * 2014-06-15 2015-12-23 Yair Feld Dialyse péritonéale implantable continue
WO2016040444A1 (fr) * 2014-09-09 2016-03-17 Baylor Research Institute Tubes intraluminaux avec des structures déployables et procédés associés

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108421148A (zh) * 2018-04-13 2018-08-21 汕头市中心医院 一种省力防脱自动正压封闭的胃管供给器
CN113289198A (zh) * 2021-04-16 2021-08-24 杭州未名信科科技有限公司 给药导管和给药导管的制备方法

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