WO2018040842A1 - Intelligent nevus flammeus photodynamic therapeutic instrument system - Google Patents

Intelligent nevus flammeus photodynamic therapeutic instrument system Download PDF

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Publication number
WO2018040842A1
WO2018040842A1 PCT/CN2017/095840 CN2017095840W WO2018040842A1 WO 2018040842 A1 WO2018040842 A1 WO 2018040842A1 CN 2017095840 W CN2017095840 W CN 2017095840W WO 2018040842 A1 WO2018040842 A1 WO 2018040842A1
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Prior art keywords
light source
treatment head
host
treatment
arm
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PCT/CN2017/095840
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French (fr)
Chinese (zh)
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刘金友
张家荣
刘成文
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武汉亚格光电技术股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0616Skin treatment other than tanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0626Monitoring, verifying, controlling systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0626Monitoring, verifying, controlling systems and methods
    • A61N2005/0627Dose monitoring systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0632Constructional aspects of the apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0664Details

Definitions

  • the invention relates to a medical device, in particular to an intelligent portrayal photodynamic therapeutic system for using a spectrum of a semiconductor luminescent material, having a highly intelligent function control, and a photosensitizer for treating port wine stains.
  • Port wine stains also known as wine-like mites or telangiectasia
  • telangiectasia are congenital diseases, frequently occurring in the face and neck, mostly unilateral, occasionally bilateral, but also in other parts of the body, sometimes involving the mucosa .
  • the damage starts from a small or a few reddish, dark red or purple red patches, which are irregular in shape, with clear boundaries and no higher than the leather surface.
  • the telangiectasia can be seen, and the partial or complete fading of the pressure is smooth. As you age, the color darkens and turns purple. 40% of patients will gradually expand their lesions. They can thicken and develop nodules before the age of 40, and are prone to bleeding after trauma.
  • Port wine stains are the flattened and rarely bulging plaques composed of numerous post-expanded posterior venules, which are congenital posterior venule malformations.
  • the area of the lesion increases with the growth of the body and does not subside.
  • Photodynamic Therapy also known as Photodynamic Therapy (PDT)
  • PDT Photodynamic Therapy
  • Photodynamic therapy is a new selective treatment technology for (vascular) proliferative lesions that developed in the late 1970s and has developed rapidly in recent years.
  • This therapy is another new treatment that is under research and rapid development after surgery, radiotherapy, chemotherapy and immunotherapy. It has become one of the most active research fields in the world of cancer prevention science.
  • Photodynamic interaction refers to the function or morphological change of organism cells or biomolecules under the action of photosensitizers, which leads to cell damage and necrosis in severe cases, and this effect must involve aerobic participation, so It is called photosensitization-oxidation. It is called photo-sensitization chemically. It is called photodynamic action in biology and medicine.
  • Photodynamic therapy is called photodynamic therapy.
  • PDT Planar degeneration
  • sputum port wine stains
  • rheumatoid arthritis fundus macular degeneration
  • restenosis after angioplasty China has started relatively late in the research and development of light source and equipment systems for photodynamic therapy, and has few varieties, which can no longer meet the needs of the growing photodynamic medicine.
  • photodynamic therapy of port wine stains requires accurate instrument parameters, accurate use parameters during treatment, stability and reliability of light source, it is directly related to the safety and effectiveness of treatment, and most cases cannot be cured at one time, so it is necessary to The patients made detailed and complete records from the initial treatment to the final treatment of various indicators, treatment parameters, treatment effects. Based on the medical characteristics of photodynamic therapy of port wine stains, it is necessary to develop a fully intelligent control photodynamic therapy system for the treatment characteristics of this case, which will promote the vigorous development of photodynamic medicine, and also be a good deed for the benefit of civilization.
  • the object of the present invention is to realize intelligent control of the whole process of the vibrancy treatment device and the whole process of the treatment of the red-spotted scorpion on the basis of the prior art, and to provide an intelligent bright-spotted sputum photodynamic therapy system.
  • an intelligent bright red spot light dynamic therapeutic apparatus system comprising a host, a treatment head and external supporting equipment, and the upper part of the main frame is connected with the lifting arm and the main treatment head through the lifting mechanism assembly, and the main treatment head
  • a semiconductor narrow-spectrum light source is used as a therapeutic light source, and a power source for generating a therapeutic light source and a computer control system box are arranged at the front of the rack, and a semiconductor narrow spectrum light source composed of a cooling water tank and a cooling water radiator is disposed at a lower portion of the rack.
  • the power source of the therapeutic light source is a microcomputer controlled semiconductor narrow spectrum working power supply
  • the host is an independent therapeutic light source host with wireless or wired network networking function, and the host is connected to the wireless through a separate 4G module.
  • the Internet, and intelligent control system with PC and smart power meter, intelligent control system transmits data through the Internet, and performs management of the working process of the therapeutic device and real-time data collection and data collection.
  • Each unit of the intelligent control system passes 4G.
  • the network performs network interconnection and data exchange, realizes resource sharing of multiple systems through a wireless or wired network, and global interconnection between the system and the system, and the host connects a contrast photo taking light source capable of automatically adjusting color temperature and brightness through a PC.
  • the photographing light source is composed of a movable smart photographing light source host with a photographing light source illuminating panel and a photosensor probe, and the photographing object is photographed by a video camera or a digital camera, and the host is disposed at the front end thereof.
  • Adjuvant therapy The receptacle connector of a movable head adjuvant therapy, adjuvant therapy head using a semiconductor light source as a narrow spectrum light treatment.
  • the semiconductor narrow spectrum light source used in the main treatment head of the host is a single semiconductor illuminator of 520 nm to 540 nm generated by a semiconductor luminescent material, and a special heat dissipation circuit board made of aluminum-based or copper-based material is integrated into a plurality of types.
  • a shape-shaped light-emitting array wherein a combined shaping lens is mounted on each of the single light sources of the integrated light source, so that the light-emitting angle of the light source is uniform and the power density is uniform, and the integrated light-emitting array circuit board is mounted on the cloth with a curved back A circulating water flow channel and a cooling water radiator that matches the size of the board.
  • the semiconductor narrow-spectrum light source used in the auxiliary treatment head is a 520 nm-540 nm semiconductor illuminator produced by a semiconductor luminescent material, and the housing of the auxiliary treatment head is provided with a skin cooling wind controller and a skin cooling fan, and the front end of the housing is in the front.
  • the optical shaping concentrating mirror, the auxiliary treatment head light source and the light source radiator are sequentially installed.
  • the illumination array of the main treatment head is equipped with an infrared ranging probe, and realizes automatic measurement and automatic positioning after setting the irradiation distance under the control of the host CPU.
  • the illumination array of the main treatment head is provided with an illumination target indicator to accurately align the illumination light to the lesion site.
  • a skin cold wind generator is arranged on both sides of the light-emitting array in front of the main treatment head, and can be
  • the illumination part controls the direction of the wind, and the wind power is controlled by the host CPU at a constant speed, and the cooling temperature is controlled between 10 ° C and 20 ° C.
  • the lifting arm and the main treatment head connected to the lifting mechanism assembly are supported by the lifting arm pivot shaft, and the rear end of the lifting arm is connected to the power worm shaft by the moving force arm assembly, and the moving force arm assembly is composed of the orbiting chamber
  • the utility model is composed of a pulley and a pulley. Under static conditions, the arm body of the lifting arm is a balanced structure supported by the pivot shaft of the lifting arm.
  • a weight can be disposed in the moving force arm assembly at the rear end of the lifting arm.
  • the invention is based on the special requirement of the treatment of the great red spot disease of the semiconductor narrow spectrum light source, and the photodynamic therapy equipment is changed from the existing on-site manual manual operation mode to the intelligent management and control mode, thereby further perfecting the special treatment for the port wine stain treatment.
  • the self-developed intelligent power meter is used to monitor the treatment power in real time to ensure the safety of the whole treatment process
  • FIG. 1 is a schematic view showing the principle of the embodiment of the therapeutic apparatus system of the present invention.
  • FIG. 2 is a block diagram showing the control principle of the therapeutic apparatus system of the present invention.
  • FIG. 3 is a schematic diagram of the principle of intelligent ranging according to the present invention.
  • FIG. 4 is a schematic view showing the working principle of the smart photographing light source of the present invention.
  • Figure 5 is a schematic diagram of the structure of the host of the present invention.
  • Figure 6 is a schematic view showing the internal structure of the main treatment head
  • Figure 7 is a schematic view showing the overall structure of the irradiation surface of the main treatment head light source
  • Figure 8 is a schematic structural view of an auxiliary treatment head
  • Figure 9 is a schematic view showing the internal structure of the auxiliary treatment head
  • Figure 10 is a schematic diagram of the principle of the lifting mechanism
  • Figure 11 is a schematic view showing the structure of the moving arm assembly of the lifting mechanism.
  • the figures in the figure indicate: 1-host, 2-4G module, 3-PC, 4-smart camera source, 5-smart power meter, 6-main treatment head, 7-digital camera, 8-assisted treatment Head, 9-patient, 10-infrared distance measuring probe, 11-photosensitive sensor probe, 12-photographing light source illuminating board, 13-lifting arm, 14-lifting mechanism assembly, 15-cooling water tank, 16-power supply and computer control system Box, 17-assisted treatment head socket, 18-frame, 19-cooling water radiator, 20-damped rotation positioning mechanism, 21-main treatment head light source, 22-illumination target indicator, 23-source water cooling system, 24- Illuminated array, 25-skin cold wind generator, 26-skin cold air window, 27-assisted treatment head plug, 28-skin cooling wind controller, 29-skin cooling fan, 30-optical shaping condenser, 31-assisted treatment head light source, 32-light source radiator, 33-coolant circulation pipe joint, 34-lift arm pivot shaft, 35-mov
  • the intelligent port wine ⁇ light power therapy system includes a host, a treatment head and an external accessory device, and the host 1 is an independent treatment light source host with wireless or wired network networking function, and the host 1 passes independent.
  • 4G module 2 connected to wireless interconnect Network, and with PC 3 intelligent power meter 5 constitutes intelligent control system, intelligent control system transmits data through the Internet, and performs management of the treatment process and real-time data collection and data collection, between each unit of intelligent control system Networked interworking data exchange through 4G networks, resource sharing of multiple systems through wireless or wired networks, and global interconnection between systems and systems;
  • the host computer 1 is connected to a comparative photo taking light source capable of automatically adjusting the color temperature and brightness through the PC 3, and the PC 3 is provided with an image analyzing system.
  • the photographing light source is composed of a movable smart photographing light source host 4 with a photographing light source illuminating panel 12 and a photosensor probe 11, and the patient 9 is photographed by a video camera or a digital camera device 7; a main treatment is connected to the host computer 1
  • the head 6 is connected to a movable auxiliary treatment head 8 via an auxiliary treatment head socket 17 provided at the front end thereof, and the auxiliary treatment head 8 uses a semiconductor narrow spectrum light source as a treatment light source.
  • the host CPU of the present invention controls the main treatment head 6 and the therapeutic illumination source of the auxiliary treatment head 8 by treating the illumination source power controller;
  • the liquid cooling system controls the cooling of the therapeutic illumination source for the primary and secondary treatment heads (6, 8); the skin cooling air generator for controlling the primary and secondary treatment heads (6, 8); and the force for controlling the illumination indicator and the host of the illumination portion
  • the arm mobile lifting mechanism receives the data sent by the intelligent power meter CPU; connects to the Internet through the 4G module 2, and performs data communication and control related to the electronic medical record, the photographing image processing, and the like with the PC 3.
  • FIG. 3 shows the principle of intelligent ranging according to the present invention.
  • the infrared ranging probe 10 is installed in the light-emitting array of the main treatment head 6, and the automatic measurement and automatic positioning after setting the irradiation distance are realized under the control of the host CPU.
  • the infrared distance measuring probe 10 is smartly installed inside the light source to ensure the accuracy of the ranging.
  • the working principle is that the infrared distance measuring probe 10 emits the test light to the lesion part of the patient, and the reflected light is reflected by the infrared distance measuring probe 10
  • the sensor receiving head receives and sends the signal to the host CPU, and the control software specially designed by the machine sends a control signal to the arm moving lifting mechanism, and the lifting mechanism makes an ascending or descending action according to the control command to complete the treatment.
  • the distance from the head to the lesion is precisely controlled.
  • the smart photographing light source detects the ambient brightness of the object to be photographed and the depth of the skin color of the subject through the photosensitive sensor probe 11 disposed in the photographing light source panel 12.
  • the collected information is fed back to the computer control system of the photographing light source, and the computer control software automatically generates brightness and color temperature information according to the information collected by the photosensor probe 11, and controls the light source to emit light, thereby ensuring that each different individual can take an image. Clear and vivid contrast photos, after computer image analysis, accurately obtain the therapeutic parameters such as the dose of photosensitizer, the power density of illumination, and the irradiation time.
  • FIG. 5 shows the main structure of the present invention.
  • the upper part of the main frame 1 is connected to the lifting arm 13 and the main treatment head 6 through the lifting mechanism assembly 14.
  • the main treatment head 6 uses a semiconductor narrow spectrum light source as a therapeutic light source, and the frame 18 adopts a vertical light source.
  • the movable structure, the front portion of the frame 18 is provided with a power source for generating a treatment light source and a computer control system box 16.
  • the lower portion of the frame 18 is provided with cooling of a semiconductor narrow spectrum light source composed of a cooling water tank 15 and a cooling water radiator 19.
  • the system, in front of the mainframe 1 rack, is also provided with an auxiliary treatment head socket 17 for connecting the auxiliary treatment head.
  • the treatment head 6 and 7 show the structure of the main treatment head 6 and its light source irradiation surface.
  • the upper back of the main treatment head 6 is connected to the front end of the lifting arm 13 by the damped rotation positioning mechanism 20, and the main treatment head 6 is housed in the main body.
  • the treatment head light source 21, the illumination target indicator 22, the light source water cooling system 23, and the infrared distance measuring probe 10 are disposed in the illumination array 24 of the main treatment head 6, and precisely align the illumination light to the lesion site.
  • the skin cold air generator 25 and the skin cold air window 26 are respectively disposed on both sides of the light-emitting array 24 in front of the main treatment head 6, and the wind direction can be controlled according to the irradiation part.
  • the wind power is controlled by the host CPU at a constant speed, and the cooling temperature is controlled at 10 ° C. Between -20 ° C.
  • the semiconductor narrow spectrum light source used in the main treatment head 6 is a single semiconductor light-emitting body of 520 nm-540 nm generated by the semiconductor light-emitting material, and a dedicated heat-dissipating circuit board made of aluminum-based or copper-based material is integrated into the light-emitting array 24, according to The design requires the use of a variety of shapes such as square, circular or shaped.
  • a combined shaping lens is mounted on each single light source of the integrated main treatment head light source 21 to make the illumination angle of the light source uniform and the power density uniform, and the integrated illumination array circuit
  • the plate is mounted on a cooling water radiator having a curved returning water flow passage and matching the size of the circuit board.
  • auxiliary treatment head 8 and 9 are schematic illustrations of the auxiliary treatment head 8 which is connected to the main body 1 via a hose-assisted auxiliary treatment head plug 27, and a skin cooling wind controller 28 is mounted in the housing of the auxiliary treatment head 8. And the skin cooling fan 29, the front end of the casing is mounted with the optical shaping condensing mirror 30, the auxiliary treatment head light source 31 and the light source radiator 32 in order from front to back. A coolant circulation pipe joint 33 is connected to the back surface of the light source radiator 32.
  • the semiconductor narrow spectrum source used by the adjunctive treatment head 8 is a 520 nm-540 nm semiconductor illuminator produced by a semiconductor luminescent material.
  • FIGS. 10 and 11 are structural diagrams of the lifting mechanism and the movable arm assembly.
  • the lifting arm 13 and the main treatment head 6 connected to the lifting mechanism assembly 14 are supported by the lifting arm pivot shaft 34, and the rear end of the lifting arm 13 is moved.
  • the arm assembly 35 is coupled to a powered worm shaft 36 that includes a track bay 42 and a pulley 43 disposed in the track bay 42.
  • the arm of the lifting arm 13 as a whole has a balanced structure supported by the lifting arm fulcrum shaft 34.
  • the lower end of the worm 39 of the power worm shaft 36 is connected to the reduction motor 40, and the weight arm 41 can be disposed in the movable force arm assembly 35 at the rear end of the lifting arm.
  • the weight of the weight 41 is determined by the force arm difference on both sides of the lifting arm pivot shaft 34 and the weight of the main treatment head 6. With the "balance principle", the balance of the weight on both sides is smaller, and the torque required for the power motor 40 is smaller. The more flexible the system is.
  • the lifting arm 13 When the pulley 43 of the movable arm assembly 35 is in the middle position of the orbital module 42, the lifting arm 13 is in a horizontal state.
  • the reduction motor 40 of the lifting arm 13 rotates forward, the worm 39 drives the power worm shaft 36 to move upward, in the lifting arm.
  • the pulley 43 Under the positioning of the fulcrum shaft 34, the pulley 43 is moved to the left, the tail portion of the lifting arm 13 is gradually pushed up, and the treatment head 6 at the head end of the lifting arm 13 is gradually lowered.
  • the speed reducing motor 40 of the lifting arm 13 is reversed, the worm 39 drives the power worm shaft 36 to move downward.
  • the invention intelligently controls all parameters of the vibrato sinus light dynamic treatment through an independent therapeutic light source host with wireless and wired networking functions, and intelligently detects the whole process of the vibrato sinus sinus power treatment.
  • Control the whole process record, its main control functions are: 1 for the precise control of the output optical power of photodynamic therapy, according to the size of the illumination area, the illumination time can accurately provide the illumination power, or according to the illumination area, the illumination power can be accurately irradiated to ensure the precise illumination time
  • the treatment effect ensures the safety of the treatment;
  • 2 The intelligent irradiation distance control function, the infrared rangefinder probe sensor of the machine, the sensor probe is skillfully installed inside the light source to ensure the accuracy of the ranging, and the special designed force arm mobile electric motor is adopted.
  • the lifting mechanism implements precise control of the distance from the irradiation treatment head to the lesion.
  • the force arm mobile electric lifting mechanism is a set of precise electromechanical system, which makes the distance control accuracy reach ⁇ 2mm, so that the therapeutic effect and treatment safety are obtained. Reliable guarantee.
  • 3 accurately set precise control of the current of the illumination source, because the output power stability of the semiconductor light source mainly depends on the operating current.
  • the system combines software and hardware to implement set current and constant current control for the working current of the light source to ensure stable output power.
  • 4 Intelligent temperature control, the light source of this system adopts liquid circulation cooling. Because the output power of the illumination source is large, the heat generation is large, the liquid circulation cooling method has high cooling efficiency, the cooling effect is uniform, and the temperature of the coolant is real-time using the independent CPU for the flow rate and temperature. monitor.
  • the invention adopts an independent 4G module to connect to the wireless internet, can realize resource sharing of multiple systems in the hospital, and can also share resources on any system in the world, that is to say, the patient can perform treatment on any one system, history treatment
  • the information can be called up.
  • the intelligent contrast photo taking light source and image analysis system adopted by the invention are aimed at the pathological characteristics of vasodilating diseases, and a special contrast photo photographing special light source is designed, which can automatically according to the skin color of the lesion part and the color of the affected area. Adjust the shooting brightness and color temperature to ensure clear and contrasting photos.
  • the photos are sent to the PC image analysis system to analyze the dilated blood vessels, the density of the affected area, and the thickness of the cortex.
  • the data is comprehensive and the dosage of the photosensitizer is selected for the doctor.
  • Basic data are provided for treatment parameters such as illumination power density and illumination time.
  • the electronic medical record designed by the invention can record the basic information of the patient in detail and treat The course of treatment, each time the treatment parameters, especially detailed records of the patient's pre- and post-treatment comparison photos and picture analysis information, must be treated multiple times for the case of port wine stains, providing detailed reference materials for the next treatment, for patients Accurate treatment, safe treatment, and effective treatment provide reliable assurance.
  • the electronic coding of each patient makes it possible for each patient to be treated on any machine in the whole network according to individual circumstances and needs.

Abstract

An intelligent nevus flammeus photodynamic therapeutic instrument system, comprising a host (1). The host (1) is an independent therapeutic light source host (1) having a wireless or wired networking function. The host (1) is connected to the wireless Internet by means of an independent 4G module (2) and forms an intelligent control system together with a PC machine (3) and an intelligent power meter (5). The intelligent control system transmits data by means of the Internet, manages the working process of the therapeutic instrument, collects and summarizes data in real time. Data exchange between all units of the intelligent control system is realized by networking a 4G network. Resource share among a plurality of systems as well as global interconnection and interworking among systems are realized by means of a wireless or wired network. The photodynamic therapeutic instrument system realizes intelligent control of a nevus flammeus photodynamic therapeutic instrument and the overall therapy process thereof according to special requirements for the therapy of nevus flammeus diseases using a semiconductor narrow-spectrum light source.

Description

智能型鲜红斑痣光动力治疗仪系统Intelligent port wine stain photodynamic therapy system 技术领域Technical field
本发明涉及医疗设备,尤其是一种采用半导体发光材料的光谱,具有高度智能化功能控制,用于配合光敏剂治疗鲜红斑痣的智能型鲜红斑痣光动力治疗仪系统。The invention relates to a medical device, in particular to an intelligent portrayal photodynamic therapeutic system for using a spectrum of a semiconductor luminescent material, having a highly intelligent function control, and a photosensitizer for treating port wine stains.
背景技术Background technique
鲜红斑痣又称葡萄酒样痣或毛细血管扩张痣,为先天性疾病,多发病于面、颈部,大多为单侧性,偶为双侧性,也有发病于身体的其他部位,有时累及粘膜。损害初起为大小不一或数个淡红、暗红或紫红色斑片,呈不规则形,边界清楚,不高出皮面,可见毛细血管扩张,压之部分或完全退色,表面平滑。随着年龄增长,颜色加深变红,变紫,40%的患者的病灶将逐渐扩张,在40岁前可增厚和出现结节,于创伤后易于出血。鲜红斑痣是无数扩张的后微静脉所组成的较扁平而很少隆起的斑块,属于先天性后微静脉畸形。病灶面积随身体生长而相应增大,终生不消退。Port wine stains, also known as wine-like mites or telangiectasia, are congenital diseases, frequently occurring in the face and neck, mostly unilateral, occasionally bilateral, but also in other parts of the body, sometimes involving the mucosa . The damage starts from a small or a few reddish, dark red or purple red patches, which are irregular in shape, with clear boundaries and no higher than the leather surface. The telangiectasia can be seen, and the partial or complete fading of the pressure is smooth. As you age, the color darkens and turns purple. 40% of patients will gradually expand their lesions. They can thicken and develop nodules before the age of 40, and are prone to bleeding after trauma. Port wine stains are the flattened and rarely bulging plaques composed of numerous post-expanded posterior venules, which are congenital posterior venule malformations. The area of the lesion increases with the growth of the body and does not subside.
光动力治疗也称光动力疗法(英文Photodynamic Therapy,简称PDT)是二十世纪七十年代末问世而在近几年来迅速发展起来的一种针对(血管)增生性病变组织的选择性治疗新技术,该疗法是完全不同于手术、放疗、化疗和免疫治疗之后的又一种正在研究、快速发展中的崭新疗法,已成为世界肿瘤防治科学中最活跃的研究领域之一。光动力作用是指在光敏剂参与下,在光的作用下,使有机体细胞或生物分子发生机能或形态变化,严重时导致细胞损伤和坏死作用,而这种作用必须有氧的参与,所以又称光敏化-氧化作用,在化学上称这种作用为光敏化作用,在生物学及医学上称之为光动力作用,用光动力作用治病的方法,称为光动力疗法。近年来,随着新的光动力治疗药物的研发成功及激光设备技术的提高,PDT又迎来了前所未有的发展高峰。同时,PDT也被用于非肿瘤型疾病,如尖锐湿疣、牛皮 癣、鲜红斑痣、类风湿关节炎、眼底黄斑病变、血管成型术后再狭窄等疾病的治疗。我国在光动力治疗用光源和设备系统的研发方面起步相对较晚,品种很少,已不能满足日益发展的光动力医学的需要。Photodynamic Therapy, also known as Photodynamic Therapy (PDT), is a new selective treatment technology for (vascular) proliferative lesions that developed in the late 1970s and has developed rapidly in recent years. This therapy is another new treatment that is under research and rapid development after surgery, radiotherapy, chemotherapy and immunotherapy. It has become one of the most active research fields in the world of cancer prevention science. Photodynamic interaction refers to the function or morphological change of organism cells or biomolecules under the action of photosensitizers, which leads to cell damage and necrosis in severe cases, and this effect must involve aerobic participation, so It is called photosensitization-oxidation. It is called photo-sensitization chemically. It is called photodynamic action in biology and medicine. Photodynamic therapy is called photodynamic therapy. In recent years, with the successful development of new photodynamic therapeutic drugs and the improvement of laser equipment technology, PDT has ushered in an unprecedented development peak. At the same time, PDT is also used for non-tumor diseases such as genital warts and cowhide. Treatment of diseases such as sputum, port wine stains, rheumatoid arthritis, fundus macular degeneration, and restenosis after angioplasty. China has started relatively late in the research and development of light source and equipment systems for photodynamic therapy, and has few varieties, which can no longer meet the needs of the growing photodynamic medicine.
作为专业从事光电技术在医疗器械领域研发和应用的科技型企业,申请人多年来致力于光动力治疗仪器和设备技术的研究,针对如何将半导体复合窄光谱应用于多种疾病的光动力治疗中,申请人曾先后提出过多件专利申请,如专利号为201320303338.5的“半导体复合窄光谱光动力治疗仪”,它采用由至少两个以上不同波长的半导体窄光谱光源复合而成的治疗光源,设计专用的窄光谱光源基板,充分利用半导体窄光谱光源的极好的波长选择性,组成不同的窄波段复合光谱,适应不同的光敏剂(光动力治疗药物)治疗时所需的最佳光谱要求,使治疗效果达到最佳。As a technology-based company specializing in the research and development and application of optoelectronic technology in the field of medical devices, the applicant has been working on photodynamic therapy instruments and equipment technology for many years, focusing on how to apply semiconductor composite narrow spectrum in photodynamic therapy for various diseases. The applicant has filed several patent applications, such as the "Semiconductor Composite Narrow-Spectrum Photodynamic Therapeutic Apparatus" with the patent number 201320303338.5, which uses a therapeutic light source composed of at least two semiconductor narrow-spectrum light sources of different wavelengths. Design a dedicated narrow-spectrum light source substrate to make full use of the excellent wavelength selectivity of semiconductor narrow-spectrum light sources to form different narrow-band composite spectra to meet the optimal spectral requirements for different photosensitizers (photodynamic therapy drugs). To achieve the best results.
由于光动力治疗鲜红斑痣要求仪器参数精准,治疗时的使用参数精准,光源的稳定性,可靠性,直接关系到治疗的安全性和有效性,并且大多数病例不能一次治愈,因此需要对每个患者从初次治疗至末次治疗的各项指标、治疗参数、治疗效果做出详细而完整的记录。基于光动力治疗鲜红斑痣的医学特点,研制一个针对该病例治疗特点的全智能化控制光动力治疗仪系统十分必要,以之推动光动力医学的蓬勃发展,同时也是造福人类的善举。Because photodynamic therapy of port wine stains requires accurate instrument parameters, accurate use parameters during treatment, stability and reliability of light source, it is directly related to the safety and effectiveness of treatment, and most cases cannot be cured at one time, so it is necessary to The patients made detailed and complete records from the initial treatment to the final treatment of various indicators, treatment parameters, treatment effects. Based on the medical characteristics of photodynamic therapy of port wine stains, it is necessary to develop a fully intelligent control photodynamic therapy system for the treatment characteristics of this case, which will promote the vigorous development of photodynamic medicine, and also be a good deed for the benefit of mankind.
发明内容Summary of the invention
本发明的目的是在现有技术基础上,采用现代智能控制技术,对鲜红斑痣的光动力治疗设备以及治疗的全过程实现智能控制,提出一种智能型鲜红斑痣光动力治疗仪系统。The object of the present invention is to realize intelligent control of the whole process of the vibrancy treatment device and the whole process of the treatment of the red-spotted scorpion on the basis of the prior art, and to provide an intelligent bright-spotted sputum photodynamic therapy system.
本发明采用的技术方案是:智能型鲜红斑痣光动力治疗仪系统,包括主机、治疗头和外部配套设备,主机机架的上方通过升降机构总成连接升降臂和主治疗头,主治疗头采用半导体窄光谱光源作为治疗光源,机架前部设置产生治疗光源的电源及电脑控制系统盒,机架内的下部设有由冷却水箱和冷却水散热器构成的半导体窄光谱光源的 冷却系统,所述治疗光源的电源为微电脑控制的半导体窄光谱工作电源,其特征在于:所述主机是一个独立的具有无线或有线网络联网功能的治疗光源主机,主机通过独立的4G模块连接无线互联网,并与PC机、智能功率计组成智能控制系统,智能控制系统通过互联网传送数据,并执行治疗仪工作过程的管理和实时进行数据收集资料汇总,智能控制系统的每个单元之间通过4G网络进行联网互通数据交换,通过无线或有线网络实现多台系统的资源共享,以及系统与系统之间的全球互联互通,所述主机通过PC机连接一个能自动调整色温和亮度的对比照片拍照光源和图像分析系统,所述拍照光源由可移动式的带拍照光源发光板和光敏传感器探头的智能拍照光源主机构成,通过视频摄像头或数码照相机对拍摄对象进行拍照,所述主机通过设在其前端的辅助治疗头插座连接一个可移动式的辅助治疗头,辅助治疗头采用半导体窄光谱光源作为治疗光源。The technical scheme adopted by the invention is: an intelligent bright red spot light dynamic therapeutic apparatus system, comprising a host, a treatment head and external supporting equipment, and the upper part of the main frame is connected with the lifting arm and the main treatment head through the lifting mechanism assembly, and the main treatment head A semiconductor narrow-spectrum light source is used as a therapeutic light source, and a power source for generating a therapeutic light source and a computer control system box are arranged at the front of the rack, and a semiconductor narrow spectrum light source composed of a cooling water tank and a cooling water radiator is disposed at a lower portion of the rack. a cooling system, wherein the power source of the therapeutic light source is a microcomputer controlled semiconductor narrow spectrum working power supply, wherein the host is an independent therapeutic light source host with wireless or wired network networking function, and the host is connected to the wireless through a separate 4G module. The Internet, and intelligent control system with PC and smart power meter, intelligent control system transmits data through the Internet, and performs management of the working process of the therapeutic device and real-time data collection and data collection. Each unit of the intelligent control system passes 4G. The network performs network interconnection and data exchange, realizes resource sharing of multiple systems through a wireless or wired network, and global interconnection between the system and the system, and the host connects a contrast photo taking light source capable of automatically adjusting color temperature and brightness through a PC. And an image analysis system, the photographing light source is composed of a movable smart photographing light source host with a photographing light source illuminating panel and a photosensor probe, and the photographing object is photographed by a video camera or a digital camera, and the host is disposed at the front end thereof. Adjuvant therapy The receptacle connector of a movable head adjuvant therapy, adjuvant therapy head using a semiconductor light source as a narrow spectrum light treatment.
所述主机的主治疗头采用的半导体窄光谱光源是将半导体发光材料产生的520nm-540nm的单颗半导体发光体,采用铝基或铜基材质制成的专用散热电路板,集成组合成多种形状的发光阵列,在集成好的光源的每个单颗光源上安装组合整形透镜,使光源的发光角度一致且功率密度均匀,所述集成好的发光阵列的电路板,安装于布有曲回形循环水流通道并和电路板大小相吻合的冷却水散热器上。The semiconductor narrow spectrum light source used in the main treatment head of the host is a single semiconductor illuminator of 520 nm to 540 nm generated by a semiconductor luminescent material, and a special heat dissipation circuit board made of aluminum-based or copper-based material is integrated into a plurality of types. a shape-shaped light-emitting array, wherein a combined shaping lens is mounted on each of the single light sources of the integrated light source, so that the light-emitting angle of the light source is uniform and the power density is uniform, and the integrated light-emitting array circuit board is mounted on the cloth with a curved back A circulating water flow channel and a cooling water radiator that matches the size of the board.
所述辅助治疗头采用的半导体窄光谱光源是半导体发光材料产生的520nm-540nm半导体发光体,所述辅助治疗头的壳体内装设有皮肤冷却风力控制器和皮肤冷却风机,壳体的前端从前至后依次安装光学整形聚光镜、辅助治疗头光源和光源散热器。The semiconductor narrow-spectrum light source used in the auxiliary treatment head is a 520 nm-540 nm semiconductor illuminator produced by a semiconductor luminescent material, and the housing of the auxiliary treatment head is provided with a skin cooling wind controller and a skin cooling fan, and the front end of the housing is in the front. The optical shaping concentrating mirror, the auxiliary treatment head light source and the light source radiator are sequentially installed.
所述主治疗头的发光阵列中装有红外测距探头,在主机CPU的控制下实现设定照射距离后的自动测量、自动定位。The illumination array of the main treatment head is equipped with an infrared ranging probe, and realizes automatic measurement and automatic positioning after setting the irradiation distance under the control of the host CPU.
所述主治疗头的发光阵列中装有照射目标指示器,将照射光精准的对准病灶部位。The illumination array of the main treatment head is provided with an illumination target indicator to accurately align the illumination light to the lesion site.
所述主治疗头前面的发光阵列两侧设有皮肤冷风发生器,可根据 照射部位控制出风方向,风力大小由主机CPU恒速控制,冷却温度控制在10℃-20℃之间。a skin cold wind generator is arranged on both sides of the light-emitting array in front of the main treatment head, and can be The illumination part controls the direction of the wind, and the wind power is controlled by the host CPU at a constant speed, and the cooling temperature is controlled between 10 ° C and 20 ° C.
所述升降机构总成连接的升降臂和主治疗头由升降臂支点转轴所支撑,升降臂的后端通过移动力臂总成与动力蜗杆轴相连接,所述移动力臂总成由轨道舱和滑轮构成,静态下,升降臂的臂身整体呈以升降臂支点转轴为支撑的平衡式结构。The lifting arm and the main treatment head connected to the lifting mechanism assembly are supported by the lifting arm pivot shaft, and the rear end of the lifting arm is connected to the power worm shaft by the moving force arm assembly, and the moving force arm assembly is composed of the orbiting chamber The utility model is composed of a pulley and a pulley. Under static conditions, the arm body of the lifting arm is a balanced structure supported by the pivot shaft of the lifting arm.
所述升降臂后端的移动力臂总成内可设置配重块。A weight can be disposed in the moving force arm assembly at the rear end of the lifting arm.
与现有技术相比,本发明的有益效果和特点是:Compared with the prior art, the beneficial effects and features of the present invention are:
本发明根据半导体窄光谱光源进行鲜红斑痣疾病治疗的特殊要求,将光动力治疗设备由现有的现场人工手动操作模式改变为智能化管理和控制模式,进一步完善了鲜红斑痣光动力治疗专用设备的各项性能:The invention is based on the special requirement of the treatment of the great red spot disease of the semiconductor narrow spectrum light source, and the photodynamic therapy equipment is changed from the existing on-site manual manual operation mode to the intelligent management and control mode, thereby further perfecting the special treatment for the port wine stain treatment. Equipment performance:
①采用自主研发的专用计算机控制系统,实施对整个系统的各项治疗参数进行精准的智能控制,确保治疗的安全性,有效性;1 Adopting a self-developed special computer control system to carry out precise and intelligent control of various treatment parameters of the whole system to ensure the safety and effectiveness of treatment;
②采用自主研制的智能功率计对治疗功率进行实时监控,确保整个治疗过程安全;2 The self-developed intelligent power meter is used to monitor the treatment power in real time to ensure the safety of the whole treatment process;
③自主研发的智能化对比照片拍照光源,根据治疗对象的肤色,病灶颜色自动调整色温和亮度,确保图片具有高的保真度,为诊断、治疗提供可靠依据;3 Self-developed intelligent contrast photo taking light source, according to the skin color of the treated object, the color of the lesion automatically adjusts the color temperature and brightness to ensure the high fidelity of the picture, providing a reliable basis for diagnosis and treatment;
④采用无线和有线互联网技术,实现系统与系统之间全球互联互通,可在地球上任何一个有互联网的地方进行多台系统的资源共享,技术交流,专家远程视频会诊,并通过电脑实时进行全球资料收集,资料汇总,为医疗管理运营商,对多台治疗系统进行实时管控提供了必要手段和可靠保证。4Using wireless and wired Internet technology to realize global interconnection between systems and systems, it can share resources, technology exchanges, expert remote video consultations and conduct real-time globally through computers on any Internet-connected place on the earth. Data collection and data collection provide necessary means and reliable guarantee for medical management operators to conduct real-time control of multiple treatment systems.
附图说明DRAWINGS
图1是本发明治疗仪系统实施例的组成原理示意图;1 is a schematic view showing the principle of the embodiment of the therapeutic apparatus system of the present invention;
图2是本发明治疗仪系统的控制原理方框图; Figure 2 is a block diagram showing the control principle of the therapeutic apparatus system of the present invention;
图3是本发明的智能测距原理示意图;3 is a schematic diagram of the principle of intelligent ranging according to the present invention;
图4是本发明的智能拍照光源工作原理示意图;4 is a schematic view showing the working principle of the smart photographing light source of the present invention;
图5是本发明的主机结构示意图;Figure 5 is a schematic diagram of the structure of the host of the present invention;
图6是主治疗头的内部结构示意图;Figure 6 is a schematic view showing the internal structure of the main treatment head;
图7是主治疗头光源照射面的整体结构示意图;Figure 7 is a schematic view showing the overall structure of the irradiation surface of the main treatment head light source;
图8是辅助治疗头的结构示意图;Figure 8 is a schematic structural view of an auxiliary treatment head;
图9是辅助治疗头的内部结构示意图;Figure 9 is a schematic view showing the internal structure of the auxiliary treatment head;
图10是升降机构的原理示意图;Figure 10 is a schematic diagram of the principle of the lifting mechanism;
图11是升降机构的移动力臂总成结构示意图。Figure 11 is a schematic view showing the structure of the moving arm assembly of the lifting mechanism.
图中标号分别表示:1-主机,2-4G模块,3-PC机,4-智能拍照光源主机,5-智能功率计,6-主治疗头,7-数码照像设备,8-辅助治疗头,9-患者,10-红外测距探头,11-光敏传感器探头,12-拍照光源发光板,13-升降臂,14-升降机构总成,15-冷却水箱,16-电源及电脑控制系统盒,17-辅助治疗头插座,18-机架,19-冷却水散热器,20-阻尼转动定位机构,21-主治疗头光源,22-照射目标指示器,23-光源水冷系统,24-发光阵列,25-皮肤冷风发生器,26-皮肤冷风窗口,27-辅助治疗头插头,28-皮肤冷却风力控制器,29-皮肤冷却风机,30-光学整形聚光镜,31-辅助治疗头光源,32-光源散热器,33-冷却液循环管接头,34-升降臂支点转轴,35-移动力臂总成,36-动力蜗杆轴,37-下降到位检测开关,38-上升到位检测开关,39-蜗杆,40-减速电机,41-配重块,42-轨道舱,43-滑轮。The figures in the figure indicate: 1-host, 2-4G module, 3-PC, 4-smart camera source, 5-smart power meter, 6-main treatment head, 7-digital camera, 8-assisted treatment Head, 9-patient, 10-infrared distance measuring probe, 11-photosensitive sensor probe, 12-photographing light source illuminating board, 13-lifting arm, 14-lifting mechanism assembly, 15-cooling water tank, 16-power supply and computer control system Box, 17-assisted treatment head socket, 18-frame, 19-cooling water radiator, 20-damped rotation positioning mechanism, 21-main treatment head light source, 22-illumination target indicator, 23-source water cooling system, 24- Illuminated array, 25-skin cold wind generator, 26-skin cold air window, 27-assisted treatment head plug, 28-skin cooling wind controller, 29-skin cooling fan, 30-optical shaping condenser, 31-assisted treatment head light source, 32-light source radiator, 33-coolant circulation pipe joint, 34-lift arm pivot shaft, 35-moving arm assembly, 36-power worm shaft, 37-down-position detection switch, 38-rising in-position detection switch, 39 - Worm, 40-gearmotor, 41-weight, 42 Orbital module, 43 pulley.
具体实施方式detailed description
下面依照附图实施例对本发明作进一步的描述:The present invention will be further described below in accordance with the embodiments of the drawings:
如图1所示,智能型鲜红斑痣光动力治疗仪系统包括主机、治疗头和外部配套设备,所述主机1是一个独立的具有无线或有线网络联网功能的治疗光源主机,主机1通过独立的4G模块2连接无线互联 网,并与PC机3、智能功率计5组成智能控制系统,智能控制系统通过互联网传送数据,并执行治疗仪工作过程的管理和实时进行数据收集资料汇总,智能控制系统的每个单元之间通过4G网络进行联网互通数据交换,通过无线或有线网络实现多台系统的资源共享,以及系统与系统之间的全球互联互通;As shown in FIG. 1 , the intelligent port wine 痣 light power therapy system includes a host, a treatment head and an external accessory device, and the host 1 is an independent treatment light source host with wireless or wired network networking function, and the host 1 passes independent. 4G module 2 connected to wireless interconnect Network, and with PC 3, intelligent power meter 5 constitutes intelligent control system, intelligent control system transmits data through the Internet, and performs management of the treatment process and real-time data collection and data collection, between each unit of intelligent control system Networked interworking data exchange through 4G networks, resource sharing of multiple systems through wireless or wired networks, and global interconnection between systems and systems;
主机1通过PC机3连接一个能自动调整色温和亮度的对比照片拍照光源,所述PC机3内设有图像分析系统。所述拍照光源由可移动式的带拍照光源发光板12和光敏传感器探头11的智能拍照光源主机4构成,通过视频摄像头或数码照相设备7对患者9进行拍照;主机1上连接有一个主治疗头6,且通过设在其前端的辅助治疗头插座17连接一个可移动式的辅助治疗头8,辅助治疗头8采用半导体窄光谱光源作为治疗光源。The host computer 1 is connected to a comparative photo taking light source capable of automatically adjusting the color temperature and brightness through the PC 3, and the PC 3 is provided with an image analyzing system. The photographing light source is composed of a movable smart photographing light source host 4 with a photographing light source illuminating panel 12 and a photosensor probe 11, and the patient 9 is photographed by a video camera or a digital camera device 7; a main treatment is connected to the host computer 1 The head 6 is connected to a movable auxiliary treatment head 8 via an auxiliary treatment head socket 17 provided at the front end thereof, and the auxiliary treatment head 8 uses a semiconductor narrow spectrum light source as a treatment light source.
图2是本发明治疗仪系统的控制原理框图,由图中看出,本发明的主机CPU通过治疗照射光源功率控制器控制主治疗头6、辅助治疗头8的治疗照射光源;通过治疗照射光源液体冷却系统控制对主、辅治疗头(6、8)的治疗照射光源冷却;控制主、辅治疗头(6、8)的皮肤冷却空气发生器;控制治疗照射部位光指示器和主机的力臂移动式升降机构;接收由智能功率计CPU发来数据;通过4G模块2联接互联网,并与PC机3进行涉及电子病历、拍照图像处理等方面的数据通讯及控制。2 is a block diagram showing the control principle of the therapeutic apparatus system of the present invention. As seen from the figure, the host CPU of the present invention controls the main treatment head 6 and the therapeutic illumination source of the auxiliary treatment head 8 by treating the illumination source power controller; The liquid cooling system controls the cooling of the therapeutic illumination source for the primary and secondary treatment heads (6, 8); the skin cooling air generator for controlling the primary and secondary treatment heads (6, 8); and the force for controlling the illumination indicator and the host of the illumination portion The arm mobile lifting mechanism receives the data sent by the intelligent power meter CPU; connects to the Internet through the 4G module 2, and performs data communication and control related to the electronic medical record, the photographing image processing, and the like with the PC 3.
图3示出本发明的智能测距原理,在主治疗头6的发光阵列中装有红外测距探头10,在主机CPU的控制下实现设定照射距离后的自动测量、自动定位。本发明将红外测距探头10巧妙的安装在光源内部,确保测距的精确度,其工作原理是:红外测距探头10将测试光发射到患者的病灶部位,反射光被红外测距探头10的传感器接收头所接收,并将信号送达主机CPU,由本机专门设计的控制软件向力臂移动式升降机构发出控制信号,升降机构根据控制指令做出升或降的动作,完成对治疗头到病灶部位的距离实施精准控制。 FIG. 3 shows the principle of intelligent ranging according to the present invention. The infrared ranging probe 10 is installed in the light-emitting array of the main treatment head 6, and the automatic measurement and automatic positioning after setting the irradiation distance are realized under the control of the host CPU. The infrared distance measuring probe 10 is smartly installed inside the light source to ensure the accuracy of the ranging. The working principle is that the infrared distance measuring probe 10 emits the test light to the lesion part of the patient, and the reflected light is reflected by the infrared distance measuring probe 10 The sensor receiving head receives and sends the signal to the host CPU, and the control software specially designed by the machine sends a control signal to the arm moving lifting mechanism, and the lifting mechanism makes an ascending or descending action according to the control command to complete the treatment. The distance from the head to the lesion is precisely controlled.
图4示出本发明的智能拍照光源的工作原理,智能拍照光源通过设在拍照光源发光板12中的光敏传感器探头11,对被拍摄对象所处的环境亮度、自身的肤色深浅进行信息探测,并将收集到的信息反馈到拍照光源的计算机控制系统,由计算机控制软件根据光敏传感器探头11所收集的信息自动生成亮度、色温信息控制光源发光,保证了每个不同的个体都能拍摄出图像清晰、色彩逼真的对比照片,经过计算机图像分析后,精确的得出鲜红斑痣治疗的光敏剂剂量、照射光功率密度、照射时间等治疗参数。4 shows the working principle of the smart photographing light source of the present invention. The smart photographing light source detects the ambient brightness of the object to be photographed and the depth of the skin color of the subject through the photosensitive sensor probe 11 disposed in the photographing light source panel 12. The collected information is fed back to the computer control system of the photographing light source, and the computer control software automatically generates brightness and color temperature information according to the information collected by the photosensor probe 11, and controls the light source to emit light, thereby ensuring that each different individual can take an image. Clear and vivid contrast photos, after computer image analysis, accurately obtain the therapeutic parameters such as the dose of photosensitizer, the power density of illumination, and the irradiation time.
图5示出本发明的主机结构,主机1机架的上方通过升降机构总成14连接升降臂13和主治疗头6,主治疗头6采用半导体窄光谱光源作为治疗光源,机架18采用立式可移动结构,机架18的前部设置产生治疗光源的电源及电脑控制系统盒16,机架18内的下部设有由冷却水箱15和冷却水散热器19构成的半导体窄光谱光源的冷却系统,主机1机架的前面还设有用于连接辅助治疗头的辅助治疗头插座17。FIG. 5 shows the main structure of the present invention. The upper part of the main frame 1 is connected to the lifting arm 13 and the main treatment head 6 through the lifting mechanism assembly 14. The main treatment head 6 uses a semiconductor narrow spectrum light source as a therapeutic light source, and the frame 18 adopts a vertical light source. The movable structure, the front portion of the frame 18 is provided with a power source for generating a treatment light source and a computer control system box 16. The lower portion of the frame 18 is provided with cooling of a semiconductor narrow spectrum light source composed of a cooling water tank 15 and a cooling water radiator 19. The system, in front of the mainframe 1 rack, is also provided with an auxiliary treatment head socket 17 for connecting the auxiliary treatment head.
图6、图7示出主治疗头6及其光源照射面的结构,主治疗头6的上方背部通过阻尼转动定位机构20连接到升降臂13的前端,主治疗头6的壳体内装设主治疗头光源21、照射目标指示器22、光源水冷系统23及红外测距探头10,照射目标指示器22设在主治疗头6的发光阵列24中,将照射光精准的对准病灶部位。主治疗头6前面的发光阵列24的两侧分别设有皮肤冷风发生器25和皮肤冷风窗口26,可根据照射部位控制出风方向,风力大小由主机CPU恒速控制,冷却温度控制在10℃-20℃之间。主治疗头6采用的半导体窄光谱光源是将半导体发光材料产生的520nm-540nm的单颗半导体发光体,采用铝基或铜基材质制成的专用散热电路板,集成组合成发光阵列24,根据设计需要可采用如方形、圆形或异形多种形状的发光阵列。在集成好的主治疗头光源21的每个单颗光源上安装组合整形透镜,使光源的发光角度一致且功率密度均匀,集成好的发光阵列的电路 板,安装于布有曲回形循环水流通道并和电路板大小相吻合的冷却水散热器上。6 and 7 show the structure of the main treatment head 6 and its light source irradiation surface. The upper back of the main treatment head 6 is connected to the front end of the lifting arm 13 by the damped rotation positioning mechanism 20, and the main treatment head 6 is housed in the main body. The treatment head light source 21, the illumination target indicator 22, the light source water cooling system 23, and the infrared distance measuring probe 10 are disposed in the illumination array 24 of the main treatment head 6, and precisely align the illumination light to the lesion site. The skin cold air generator 25 and the skin cold air window 26 are respectively disposed on both sides of the light-emitting array 24 in front of the main treatment head 6, and the wind direction can be controlled according to the irradiation part. The wind power is controlled by the host CPU at a constant speed, and the cooling temperature is controlled at 10 ° C. Between -20 ° C. The semiconductor narrow spectrum light source used in the main treatment head 6 is a single semiconductor light-emitting body of 520 nm-540 nm generated by the semiconductor light-emitting material, and a dedicated heat-dissipating circuit board made of aluminum-based or copper-based material is integrated into the light-emitting array 24, according to The design requires the use of a variety of shapes such as square, circular or shaped. A combined shaping lens is mounted on each single light source of the integrated main treatment head light source 21 to make the illumination angle of the light source uniform and the power density uniform, and the integrated illumination array circuit The plate is mounted on a cooling water radiator having a curved returning water flow passage and matching the size of the circuit board.
图8、图9是辅助治疗头8的结构示意,辅助治疗头8通过软管连接的辅助治疗头插头27与主机1相连接,辅助治疗头8的壳体内装设有皮肤冷却风力控制器28和皮肤冷却风机29,壳体的前端从前至后依次安装光学整形聚光镜30、辅助治疗头光源31和光源散热器32。光源散热器32的背面连接一个冷却液循环管接头33。辅助治疗头8采用的半导体窄光谱光源是半导体发光材料产生的520nm-540nm半导体发光体。8 and 9 are schematic illustrations of the auxiliary treatment head 8 which is connected to the main body 1 via a hose-assisted auxiliary treatment head plug 27, and a skin cooling wind controller 28 is mounted in the housing of the auxiliary treatment head 8. And the skin cooling fan 29, the front end of the casing is mounted with the optical shaping condensing mirror 30, the auxiliary treatment head light source 31 and the light source radiator 32 in order from front to back. A coolant circulation pipe joint 33 is connected to the back surface of the light source radiator 32. The semiconductor narrow spectrum source used by the adjunctive treatment head 8 is a 520 nm-540 nm semiconductor illuminator produced by a semiconductor luminescent material.
图10、图11是升降机构及移动力臂总成的结构示意,升降机构总成14连接的升降臂13和主治疗头6由升降臂支点转轴34所支撑,升降臂13的后端通过移动力臂总成35与动力蜗杆轴36相连接,移动力臂总成35包括轨道舱42及设于轨道舱42中的滑轮43。静态下,升降臂13的臂身整体呈以升降臂支点转轴34为支撑的平衡式结构。动力蜗杆轴36的蜗杆39下端连接减速电机40,升降臂后端的移动力臂总成35内可设置配重块41。该配重块41的重量由升降臂支点转轴34两边的力臂差和主治疗头6的重量所决定,利用“天平原理”,两边的重量越平衡,动力减速电机40所需的力矩越小,系统运转越灵活。10 and 11 are structural diagrams of the lifting mechanism and the movable arm assembly. The lifting arm 13 and the main treatment head 6 connected to the lifting mechanism assembly 14 are supported by the lifting arm pivot shaft 34, and the rear end of the lifting arm 13 is moved. The arm assembly 35 is coupled to a powered worm shaft 36 that includes a track bay 42 and a pulley 43 disposed in the track bay 42. Under static conditions, the arm of the lifting arm 13 as a whole has a balanced structure supported by the lifting arm fulcrum shaft 34. The lower end of the worm 39 of the power worm shaft 36 is connected to the reduction motor 40, and the weight arm 41 can be disposed in the movable force arm assembly 35 at the rear end of the lifting arm. The weight of the weight 41 is determined by the force arm difference on both sides of the lifting arm pivot shaft 34 and the weight of the main treatment head 6. With the "balance principle", the balance of the weight on both sides is smaller, and the torque required for the power motor 40 is smaller. The more flexible the system is.
当移动力臂总成35的滑轮43处于轨道舱42中间位置时,升降臂13处于水平状态,当升降臂13的减速电机40正转时,蜗杆39带动动力蜗杆轴36向上运动,在升降臂支点转轴34的定位作用下,滑轮43向左移动,升降臂13的尾部逐步推高,升降臂13头端的治疗头6逐步向下。相反,当升降臂13的减速电机40反转时,蜗杆39带动动力蜗杆轴36向下运动,在升降臂支点转轴34的定位作用下,移动力臂总成35的滑轮43向右移动,升降臂13的尾部被逐步拉低,升降臂13头端的治疗头6逐步向上,从而实现了治疗头6所需要的上升和下降运动。 When the pulley 43 of the movable arm assembly 35 is in the middle position of the orbital module 42, the lifting arm 13 is in a horizontal state. When the reduction motor 40 of the lifting arm 13 rotates forward, the worm 39 drives the power worm shaft 36 to move upward, in the lifting arm. Under the positioning of the fulcrum shaft 34, the pulley 43 is moved to the left, the tail portion of the lifting arm 13 is gradually pushed up, and the treatment head 6 at the head end of the lifting arm 13 is gradually lowered. On the contrary, when the speed reducing motor 40 of the lifting arm 13 is reversed, the worm 39 drives the power worm shaft 36 to move downward. Under the positioning of the lifting arm fulcrum shaft 34, the pulley 43 of the moving arm assembly 35 moves to the right, lifting The tail of the arm 13 is gradually lowered, and the treatment head 6 at the head end of the lifting arm 13 is gradually moved upward, thereby achieving the required ascending and descending movement of the treatment head 6.
实际应用中:本发明通过独立的具有无线和有线联网功能的治疗光源主机,对鲜红斑痣光动力治疗的全部参数进行智能控制,智能检测,对鲜红斑痣光动力治疗的全过程实施了智能控制全程记录,其主要控制功能有:①对光动力治疗的输出光功率进行精准控制,能根据照射面积大小,照射时间精准提供出照射功率,或者根据照射面积,照射功率提出精准照射时间,确保治疗效果,确保治疗安全;②智能照射距离控制功能,本机的红外测距探头式传感器,将传感器探头巧妙的安装在光源内部,确保测距的精准度,采用专用设计的力臂移动式电动升降机构,对照射治疗头到病灶部的距离实施精准控制,力臂移动式电动升降机构是一套精密的机电系统,使测距控制精度达到了±2mm,使治疗效果和治疗安全性得到了可靠保证。③对照射光源的电流实施精准设定精准控制,由于半导体光源的输出功率稳定性主要取决于工作电流。本系统采用软件和硬件相结合,对光源的工作电流实施设定电流,恒流控制,保证输出功率稳定。④智能温度控制,本系统光源采用液体循环冷却,由于照射光源输出功率大,发热量大,采用液体循环冷却方式冷却效率高,冷却效果均匀,冷却液的温度采用独立CPU对流速和温度进行实时监控。In practical application: the invention intelligently controls all parameters of the vibrato sinus light dynamic treatment through an independent therapeutic light source host with wireless and wired networking functions, and intelligently detects the whole process of the vibrato sinus sinus power treatment. Control the whole process record, its main control functions are: 1 for the precise control of the output optical power of photodynamic therapy, according to the size of the illumination area, the illumination time can accurately provide the illumination power, or according to the illumination area, the illumination power can be accurately irradiated to ensure the precise illumination time The treatment effect ensures the safety of the treatment; 2The intelligent irradiation distance control function, the infrared rangefinder probe sensor of the machine, the sensor probe is skillfully installed inside the light source to ensure the accuracy of the ranging, and the special designed force arm mobile electric motor is adopted. The lifting mechanism implements precise control of the distance from the irradiation treatment head to the lesion. The force arm mobile electric lifting mechanism is a set of precise electromechanical system, which makes the distance control accuracy reach ±2mm, so that the therapeutic effect and treatment safety are obtained. Reliable guarantee. 3 accurately set precise control of the current of the illumination source, because the output power stability of the semiconductor light source mainly depends on the operating current. The system combines software and hardware to implement set current and constant current control for the working current of the light source to ensure stable output power. 4 Intelligent temperature control, the light source of this system adopts liquid circulation cooling. Because the output power of the illumination source is large, the heat generation is large, the liquid circulation cooling method has high cooling efficiency, the cooling effect is uniform, and the temperature of the coolant is real-time using the independent CPU for the flow rate and temperature. monitor.
本发明采用独立的4G模块连接无线互联网,可实现医院内部多台系统的资源共享,也可在全球任意一台系统上资源共享,也就是说患者可以在任意一台系统上进行治疗,历史治疗信息的可查阅调用。本发明采用的智能对比照片拍照光源和图像分析系统,针对鲜红斑痣是一种血管扩张性疾病的病理特点,设计了专用的对比照片拍照专用光源,能根据病灶部位的肤色,和患处颜色自动调整拍摄亮度和色温,确保照片清晰对比度分明,照片送入PC图像分析系统,对患处的扩张血管分别,疏密度,皮层厚度等进行分析,得出全方位数据,为医生选取治疗光敏剂的用量、照射光功率密度、照射时间等治疗参数提供基础数据。The invention adopts an independent 4G module to connect to the wireless internet, can realize resource sharing of multiple systems in the hospital, and can also share resources on any system in the world, that is to say, the patient can perform treatment on any one system, history treatment The information can be called up. The intelligent contrast photo taking light source and image analysis system adopted by the invention are aimed at the pathological characteristics of vasodilating diseases, and a special contrast photo photographing special light source is designed, which can automatically according to the skin color of the lesion part and the color of the affected area. Adjust the shooting brightness and color temperature to ensure clear and contrasting photos. The photos are sent to the PC image analysis system to analyze the dilated blood vessels, the density of the affected area, and the thickness of the cortex. The data is comprehensive and the dosage of the photosensitizer is selected for the doctor. Basic data are provided for treatment parameters such as illumination power density and illumination time.
本发明所设计专用的电子病历,可详细记录病人的基本信息,治 疗过程,每次的治疗参数,特别是详细记录病人的治疗前后对比照片和图片分析信息,针对鲜红斑痣病例必须进行多次治疗的特点,为下一次的治疗提供详实的参考资料,为病人的精准治疗,安全治疗,有效治疗提供可靠保证。每个病人的电子编码,使每个患者根据个人情况和需要全网内实现在任意一台机器上治疗提供了可能。 The electronic medical record designed by the invention can record the basic information of the patient in detail and treat The course of treatment, each time the treatment parameters, especially detailed records of the patient's pre- and post-treatment comparison photos and picture analysis information, must be treated multiple times for the case of port wine stains, providing detailed reference materials for the next treatment, for patients Accurate treatment, safe treatment, and effective treatment provide reliable assurance. The electronic coding of each patient makes it possible for each patient to be treated on any machine in the whole network according to individual circumstances and needs.

Claims (10)

  1. 一种智能型鲜红斑痣光动力治疗仪系统,包括主机、治疗头和外部配套设备,主机机架的上方通过升降机构总成连接升降臂和主治疗头,主治疗头采用半导体窄光谱光源作为治疗光源,机架前部设置产生治疗光源的电源及电脑控制系统盒,机架内的下部设有由冷却水箱和冷却水散热器构成的半导体窄光谱光源的冷却系统,所述治疗光源的电源为微电脑控制的半导体窄光谱工作电源,其特征在于:所述主机是一个独立的具有无线或有线网络联网功能的治疗光源主机,主机通过独立的4G模块连接无线互联网,并与PC机、智能功率计组成智能控制系统,智能控制系统通过互联网传送数据,并执行治疗仪工作过程的管理和实时进行数据收集资料汇总,智能控制系统的每个单元之间通过4G网络进行联网互通数据交换,通过无线或有线网络实现多台系统的资源共享,以及系统与系统之间的全球互联互通,所述主机通过安装有电子病历和图像分析系统的PC机连接一个能自动调整色温和亮度的对比照片拍照光源系统,所述拍照光源由可移动式的带拍照光源发光板和光敏传感器探头的智能拍照光源主机构成,通过视频摄像头或数码照相机对拍摄对象进行拍照,所述主机通过设在其前端的辅助治疗头插座连接一个可移动式的辅助治疗头,辅助治疗头采用半导体窄光谱光源作为治疗光源。The utility model relates to an intelligent bright red spot light dynamic therapeutic apparatus system, which comprises a host machine, a treatment head and an external supporting device. The upper part of the main frame is connected with the lifting arm and the main treatment head through a lifting mechanism assembly, and the main treatment head adopts a semiconductor narrow spectrum light source as a The treatment light source is provided with a power source for generating a treatment light source and a computer control system box at the front of the rack, and a lower part of the rack is provided with a cooling system of a semiconductor narrow spectrum light source composed of a cooling water tank and a cooling water radiator, and the power source of the treatment light source The micro-computer controlled semiconductor narrow spectrum working power supply is characterized in that: the host is an independent therapeutic light source host with wireless or wired network networking function, and the host connects to the wireless internet through an independent 4G module, and is connected with the PC and the smart power. The intelligent control system is composed of intelligent control system, and the intelligent control system transmits data through the Internet, and performs management of the working process of the therapeutic device and real-time data collection and data collection. Each unit of the intelligent control system exchanges data through the 4G network for interconnection and communication. Or a wired network to achieve resources for multiple systems. And a global interconnection between the system and the system, the host connected to a comparative photo taking light source system capable of automatically adjusting color temperature and brightness by a PC equipped with an electronic medical record and image analysis system, the photographing light source being movable The utility model is composed of a smart photographing light source host with a photo light source illuminating board and a photosensor probe, and the photographing object is photographed by a video camera or a digital camera, and the host connects a movable auxiliary treatment through an auxiliary treatment head socket provided at the front end thereof. The head, the auxiliary treatment head uses a semiconductor narrow-spectrum light source as a therapeutic light source.
  2. 根据权利要求1所述的智能型鲜红斑痣光动力治疗仪系统,其特征在于所述主机的主治疗头采用的半导体窄光谱光源是将半导体发光材料产生的520nm-540nm的单颗半导体发光体,采用铝基或铜基材质制成的专用散热电路板,集成组合成多种形状的发光阵列,在集成好的光源的每个单颗光源上安装组合整形透镜,使光源的发光角度一致且功率密度均匀,所述集成好的发光阵列的电路板,安装于布有曲回形循环水流通道并和电路板大小相吻合的冷却水散热器上。The intelligent port wine stain photodynamic therapy system according to claim 1, wherein the semiconductor narrow spectrum source used by the main treatment head of the host is a single semiconductor illuminant of 520 nm to 540 nm generated by the semiconductor luminescent material. A dedicated heat-dissipating circuit board made of aluminum-based or copper-based material is integrated into a plurality of shapes of light-emitting arrays, and a combined shaping lens is mounted on each single light source of the integrated light source to make the light-emitting angles of the light source uniform. The power density is uniform, and the circuit board of the integrated light-emitting array is mounted on a cooling water radiator that is provided with a curved-shaped circulating water flow channel and matches the size of the circuit board.
  3. 根据权利要求1所述的智能型鲜红斑痣光动力治疗仪系统,其特征在于所述辅助治疗头采用的半导体窄光谱光源是半导体发光 材料产生的520nm-540nm半导体发光体,所述辅助治疗头的壳体内装设有皮肤冷却风力控制器和皮肤冷却风机,壳体的前端从前至后依次安装光学整形聚光镜、辅助治疗头光源和光源散热器。The intelligent port wine stain photodynamic therapy system according to claim 1, wherein the semiconductor narrow spectrum light source used in the auxiliary treatment head is semiconductor light emitting a 520nm-540nm semiconductor illuminator produced by the material, the skin of the auxiliary treatment head is provided with a skin cooling wind controller and a skin cooling fan, and the front end of the housing is sequentially installed with an optical shaping condensing mirror, an auxiliary treatment head light source and a light source from front to back. heat sink.
  4. 根据权利要求2所述的智能型鲜红斑痣光动力治疗仪系统,其特征在于所述主治疗头的发光阵列中装有红外测距探头,在主机CPU的控制下实现设定照射距离后的自动测量、自动定位。The intelligent port wine stain photodynamic therapy system according to claim 2, wherein the illumination array of the main treatment head is equipped with an infrared ranging probe, and the illumination distance is set under the control of the host CPU. Automatic measurement, automatic positioning.
  5. 根据权利要求2所述的智能型鲜红斑痣光动力治疗仪系统,其特征在于所述主治疗头的发光阵列中装有照射目标指示器,用于将照射光精准的对准病灶部位。The intelligent port wine stain photodynamic therapy system according to claim 2, wherein the illumination array of the main treatment head is provided with an illumination target indicator for accurately aligning the illumination light to the lesion site.
  6. 根据权利要求2所述的智能型鲜红斑痣光动力治疗仪系统,其特征在于所述主治疗头前面的发光阵列两侧设有皮肤冷风发生器和皮肤冷风窗口,用于根据照射部位控制出风方向,风力大小由主机CPU恒速控制,冷却温度控制在10℃-20℃之间。The intelligent port wine stain photodynamic therapy system according to claim 2, wherein a skin cold wind generator and a skin cold air window are arranged on both sides of the light-emitting array in front of the main treatment head, and are controlled according to the irradiation portion. In the wind direction, the wind power is controlled by the host CPU at a constant speed, and the cooling temperature is controlled between 10 ° C and 20 ° C.
  7. 根据权利要求1所述的智能型鲜红斑痣光动力治疗仪系统,其特征在于所述升降机构总成连接的升降臂和主治疗头由升降臂支点转轴所支撑,升降臂的后端通过移动力臂总成与动力蜗杆轴相连接,所述移动力臂总成由轨道舱和滑轮构成,静态下,升降臂的臂身整体呈以升降臂支点转轴为支撑的平衡式结构。The intelligent port wine stain photodynamic therapy system according to claim 1, wherein the lifting arm and the main treatment head connected to the lifting mechanism assembly are supported by the lifting arm pivot shaft, and the rear end of the lifting arm is moved. The arm assembly is connected to the power worm shaft. The moving arm assembly is composed of a track cabin and a pulley. Under static conditions, the arm of the lift arm is a balanced structure supported by the pivot shaft of the lift arm.
  8. 根据权利要求7所述的智能型鲜红斑痣光动力治疗仪系统,其特征在于所述升降臂后端的移动力臂总成内设配重块。The intelligent port wine stain photodynamic therapy system according to claim 7, wherein the moving arm assembly at the rear end of the lifting arm is provided with a weight.
  9. 一种鲜红斑痣的治疗方法,采用权利要求1-8中任一项所述治疗仪系统进行,其特征在于所述方法包括如下步骤:A method of treating port wine stains using the therapeutic apparatus system of any of claims 1-8, characterized in that the method comprises the steps of:
    步骤一、拍照光源系统的光敏传感器探头对治疗对象的肤色、病灶颜色进行探测,根据探测结果调整拍照光源发光板的色温和亮度,然后通过视频摄像头或数码照相机对治疗对象进行拍照,将所拍照片输送至PC机的图像分析系统进行分析处理,得出鲜红斑痣治疗的治疗参数,所述治疗参数包括光敏剂剂量、照射光功率密度、照射时间,所述治疗参数由PC机传送至主机; Step 1. The photosensitive sensor probe of the photographing light source system detects the skin color and the color of the lesion of the treatment object, adjusts the color temperature and brightness of the photographing light source illuminating panel according to the detection result, and then takes a photo of the therapeutic object through a video camera or a digital camera, and takes the photo The image is sent to an image analysis system of the PC for analysis and processing, and the treatment parameters of the treatment of port wine stains are obtained. The treatment parameters include a dose of the photosensitizer, a power density of the illumination light, and an irradiation time, and the treatment parameters are transmitted from the PC to the host. ;
    步骤二、主机上连接的主治疗头和辅助治疗头均采用半导体窄光谱光源作为治疗光源,主治疗头的发光阵列中装有红外测距探头,主机根据红外测距探头探测的与治疗对象的病灶部位的距离,向力臂移动式升降机构发出控制信号,升降机构根据控制指令做出升或降的动作,完成对主治疗头到病灶部位的距离实施精准控制,主机通过设在其前端的辅助治疗头插座连接可移动式的辅助治疗头;步骤三、主机通过治疗照射光源功率控制器控制主治疗头和辅助治疗头的治疗光源,按照PC机传送的治疗参数对病灶部位进行照射治疗,同时通过治疗照射光源液体冷却系统控制对主、辅治疗头的治疗照射光源进行冷却。Step 2: The main treatment head and the auxiliary treatment head connected to the host adopt a semiconductor narrow spectrum light source as a treatment light source, and the illumination array of the main treatment head is equipped with an infrared distance measuring probe, and the host detects the target object according to the infrared distance measuring probe. The distance of the lesion part sends a control signal to the mobile arm lifting and lifting mechanism, and the lifting mechanism makes an ascending or descending action according to the control instruction, and performs precise control on the distance from the main treatment head to the lesion site, and the host computer is disposed at the front end thereof. The auxiliary treatment head socket is connected with the movable auxiliary treatment head; in step 3, the host computer controls the treatment light source of the main treatment head and the auxiliary treatment head by treating the illumination source power controller, and irradiating the lesion portion according to the treatment parameters transmitted by the PC, At the same time, the therapeutic illumination source of the primary and secondary treatment heads is cooled by the treatment of the illumination source liquid cooling system.
  10. 如权利要求9所述的鲜红斑痣的治疗方法,其特征在于:所述力臂移动式升降机构包括移动力臂总成、升降臂、动力蜗杆轴,升降臂的后端通过移动力臂总成与动力蜗杆轴相连接,升降臂还通过升降臂支点转轴与支架转动连接,升降臂的前端与主治疗头连接,静态下升降臂的臂身整体呈以升降臂支点转轴为支撑的平衡式结构,动力蜗杆轴由驱动装置驱动实现上升或下降以带动移动力臂总成及与移动力臂总成连接的升降臂的一端上升或下降。 The method for treating port wine stains according to claim 9, wherein the force arm moving lifting mechanism comprises a moving arm assembly, a lifting arm, a power worm shaft, and a rear end of the lifting arm passes the moving arm total The shaft is connected with the power worm shaft, and the lifting arm is also rotatably connected to the bracket through the pivot shaft of the lifting arm, and the front end of the lifting arm is connected with the main treatment head. The arm of the static lower lifting arm is balanced by the pivot shaft of the lifting arm. The structure, the power worm shaft is driven by the driving device to rise or fall to drive the moving arm assembly and the end of the lifting arm connected to the moving arm assembly to rise or fall.
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