WO2018036875A1 - Pompe à seringue présentant une procédé amélioré de mise en place de seringues pour éviter des administrations non souhaitées de bolus - Google Patents

Pompe à seringue présentant une procédé amélioré de mise en place de seringues pour éviter des administrations non souhaitées de bolus Download PDF

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Publication number
WO2018036875A1
WO2018036875A1 PCT/EP2017/070713 EP2017070713W WO2018036875A1 WO 2018036875 A1 WO2018036875 A1 WO 2018036875A1 EP 2017070713 W EP2017070713 W EP 2017070713W WO 2018036875 A1 WO2018036875 A1 WO 2018036875A1
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WO
WIPO (PCT)
Prior art keywords
syringe
drive
drive head
coupling
clutch
Prior art date
Application number
PCT/EP2017/070713
Other languages
German (de)
English (en)
Inventor
Rolf Heitmeier
Josef GERLACH
René Wildner
Dirk ALJETS
Original Assignee
B. Braun Melsungen Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B. Braun Melsungen Ag filed Critical B. Braun Melsungen Ag
Publication of WO2018036875A1 publication Critical patent/WO2018036875A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1458—Means for capture of the plunger flange
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies

Definitions

  • the present invention relates to a Sphtzenpumpe for automated
  • Drug with a largely defined volume flow over a long period is possible and ensured.
  • highly effective drugs are applied by means of infusion syringe pumps.
  • a filled with a corresponding drug syringe is inserted and fixed in the device.
  • a promotion of the drug from the syringe ensures a drive over which the inserted into the device syringe is actuated.
  • Infusion syringes usually consist of plastic and one by one
  • Piston rod in a syringe barrel slidable piston made of an elastomer. These materials are reversibly deformable within certain force / pressure ranges, so that it can lead to changes in the volume enclosed by the syringe plunger with pressure variations in the syringe barrel.
  • patient blood may be aspirated or an undefined amount of medication delivered to the patient.
  • a change or insertion of a syringe can basically either after a manual or after an automatic
  • the syringe plunger When manually inserting or changing, the syringe plunger is to be manually coupled with the syringe pump and its drive. This is usually the case Insert the syringe into a syringe holder of the pump whose drive head is decoupled from the drive by a lever mechanism.
  • the drive head is positioned in the sequence relative to the syringe by hand and is delivered after inserting the syringe in the syringe pump by an operator by hand in the direction of the syringe plunger. If the drive head touches a piston plate of the syringe plunger, the user adjusts the feed motion of the drive head and couples it back to the drive by actuating the lever mechanism.
  • the piston plate is automatically mechanically or firmly connected by manual operation of the operator with the drive head. This can lead to unnoticed pressure variations in the syringe, which balance when connected to the patient, so that it can come to the above-described aspiration of patient's blood or to a dose of uncontrolled amounts of medication during a short period.
  • Piston plate must be performed simultaneously. In particular, if rapid start-up of the pump, e.g. in acute circulatory problems one
  • Piston plate can lead to an unwanted medication bolus, which may even not be detected. Lack of axial fixation of the syringe barrel may result in unwanted drug flow.
  • Syringe plunger before.
  • a sensor immediately stops the motor movement when the drive head touches the piston plate. This is followed by a mechanical coupling of the piston plate with the drive head.
  • a pressure build-up in the syringe can be avoided by the sensor-controlled movement of the drive head and the so controlled acting forces.
  • Syringe change by the user can not be influenced, but is determined by the automatic processes.
  • the device is relatively complex and expensive, since a multi-stage apron sensor for initiating the
  • Electromagnets are required.
  • syringe pumps with automatic syringe change may be that the time required for a syringe change from the maximum travel speed of the drive head to the end position and back and is determined by their position relative to the piston plate. This can be problematic in some applications, especially if a rapid onset of drug administration is required. In these cases, the traversing speed of the drive head dictates the time until infusion start and can not be shortened by the user.
  • the piston plate is connected as part of the syringe directly to the drive of the syringe pump. Forces from the drive in the direction of movement of the syringe plunger are exerted on the syringe via the piston plate and cause a controlled emptying of the syringe.
  • different syringes usually have different piston plates, which vary in diameter and thickness differ. This can cause the piston plate is not sufficiently fixed to the drive head and dissolves in vibration or a negative pressure in the syringe barrel. There may be an uncontrolled flow of medication to the patient.
  • There are known Kolbenplattenfix isten in which a braking device for the piston rod is provided to achieve a safe and the patient not endangering function. This prevents it during the fixing of the piston plate on the drive head to a displacement of the piston rod can come in the axial direction.
  • the syringe is held over its cylinder in the syringe pump and fixed. Different syringes usually have different
  • Syringe barrel diameters and lengths The result is that the syringe cylinder as well as the piston plate of the syringe piston in the radial direction relative to the contact surface of the syringe holder have different distances, so that the drive head contacts this at different points. This can lead to tilting of the piston rod.
  • Piston plate produce a force component that acts in the radial direction of the piston rod of the syringe. As a result, there may be a tilting of the piston rod, so that they jammed in the syringe barrel and the
  • the invention has for its object to provide a medical syringe pump, which does not have the aforementioned disadvantages of known pumps.
  • the pump should be user-friendly and easy to use, with a view to a syringe change rapid availability of the drug should be given to the patient, without this being compromised by inaccurate or deviant drug administration, for example due to an unwanted pressure buildup in the syringe barrel.
  • the coupling of the syringe plunger of a syringe with the drive of the syringe pump always a solid, safe and correct coupling should be ensured.
  • the drive head in the decoupled state can be positioned manually relative to the cylinder receptacle.
  • the inventive design of the syringe pump causes an immediate and only with a slight delay automatic re-coupling. As a result, the drive head can not be moved in the coupled state without adjustment of the drive.
  • the drive head is fixed in the coupled state due to its coupling with the drive relative to the cylinder receptacle and a relative positioning of the drive head with respect to the cylinder receptacle and a syringe therein is not possible. Unintentional medication is thus without an adjustment of the drive, which is preferably controlled and braked by a control of the pump or im Standstill is fixed, not possible.
  • the invention can allow a bolus-free insertion of the syringe in the syringe pump, but unlike in known pumps that allow such, yet a particularly fast and effective disassembly and assembly of a syringe by manually adjusting the syringe pump is possible. Further, by the invention, travel paths in which the Spntzenkolbenplatte and the drive head (yet) are not yet engaged or in contact with each other, particularly fast and independent of the maximum
  • Traversing speed of the drive can be moved manually.
  • Syringe plunger could be done in the syringe barrel.
  • the object underlying the invention is achieved by a method for inserting a syringe in a syringe pump, in particular in a syringe pump according to the invention, the present
  • Cylinder receptacle for a syringe barrel of the syringe one opposite the
  • Cylinder seat relatively positionable drive head for contacting
  • a drive for their relative positioning and operable by an operator coupling unit for coupling and decoupling the drive with the drive head, wherein the coupling unit is actuated by an operator, whereby the drive and the drive head decoupled, in particular mechanically decoupled,
  • the drive head is subsequently positioned manually relative to the cylinder receptacle in a change position enabling insertion of a syringe
  • a syringe is inserted into the cylinder receptacle and subsequently positioned the drive head in the direction of cylinder mount, in particular manually positioned, and is brought into contact with the Spntzenkolbenplatte, wherein when Intakingschreib of Spentzenkolbenplatte and drive head of the drive is automatically coupled to the drive head.
  • this automatic coupling of the drive head and the cylinder receiving each other are relatively positioned and fixed (a manual positioning of the drive head is no longer possible), so that their relative position to each other and thus also the position of the syringe plunger in the syringe barrel is determined and maintained.
  • axial direction refers to a direction parallel to the central longitudinal axis of a syringe intentionally received in the syringe pump
  • radial direction refers to a direction orthogonal thereto.
  • the invention is not limited to a positioning of the drive head relative to the cylinder receptacle, but also includes embodiments in which the cylinder receptacle is positioned relative to the drive head or can be positioned.
  • the coupling unit can be fixed relative to the drive head. It may in particular be connected in the axial direction fixed to the drive head, for example via a push rod or guide rod or other, in particular thrust forces in the axial direction between the coupling unit and drive head transmitting unit. In this way, the coupling unit and the drive head can be positioned together in the axial direction relative to the cylinder receptacle. Is the
  • the coupling unit can be freely positioned together with the drive head by a manual operator-side operation relative to the cylinder and the drive.
  • Syringe cylinder is designed and held.
  • An embodiment of the invention is characterized in that the coupling unit has a first clutch interacting directly or indirectly with the drive and a second clutch interacting directly or indirectly with the drive head.
  • the first clutch can be used in particular as a mechanical Clutch may be formed, while the second clutch may be formed in particular as an electromagnetic clutch.
  • the first coupling preferably causes a coupling or decoupling of the drive head together with the coupling unit with the drive or from the drive. If the first clutch is decoupled, the drive head can be manually positioned with the coupling unit. If the first clutch is coupled, a drive torque can be transmitted from the drive to the coupling unit and the drive head and so a motor-driven positioning of the drive head can be effected and a manual positioning of the drive head is not possible.
  • Task and effect of the second clutch is, in the case of a
  • the second clutch is automatically decoupled in the case of a contact and transferred to its decoupled position, wherein it entrains the first clutch and transferred to the coupled state.
  • the automatic decoupling can be done for example by applying a bias, for example by a spring, to the second clutch.
  • the first clutch can be decoupled by a user-side actuation of the coupling unit, in particular when the second clutch is coupled. For example, via the coupled second clutch, a displacement exerted on the coupling unit by an operator can be transmitted in the axial direction to the first clutch. As a result of such a displacement in the axial direction, the first clutch can be transferred from the coupled state to the uncoupled state.
  • first clutch is biased in its coupled position, in particular by means of a spring / compression spring. This promotes re-engagement of the first clutch and thereby coupling the drive and drive head in the event of mutual contacting of syringe plunger plate and drive head.
  • the coupling unit may have an operatively connected to the second clutch actuator for decoupling the first clutch.
  • This can cooperate with at least one coupling element of the first clutch, preferably in such a way that the coupling element (coupled) in a the drive with the drive head coupling position (coupled) and in a drive from the drive head uncoupled position (decoupled) can be positioned.
  • the coupling element may be a pivotably arranged on the coupling unit coupling arm, which is operatively connected via an inclined plane or sliding bevel with the actuator.
  • the actuator may in particular be formed as a sleeve, on the one hand with the second clutch and on the other hand with the coupling element or the coupling elements of the first
  • Coupling is operatively connected. It can in particular be positioned, for example displaced, by actuation of the second clutch relative to the first clutch and thus the coupling element.
  • the first clutch is actuated and in particular coupled or decoupled.
  • the coupling element may be operatively connected in its coupled position directly or indirectly via a transmission unit with the drive. In the coupled position, the coupling unit can be positioned by the action of the drive relative to the cylinder receptacle, in particular positionable in the axial direction.
  • the actuator is biased by a compression spring, which is supported on the one hand on the actuator and on the other hand on the coupling element and biases the first clutch in its coupled position.
  • An embodiment of the invention is characterized in that the second clutch comprises an electromagnet.
  • the second clutch may be actuated by a user-side actuation of the coupling unit in its uncoupling position and by energizing the electromagnet in its coupling position
  • the second clutch can in particular by the
  • Electromagnet be held in its coupled position. If the energization of the electromagnet is set, the second clutch is decoupled or can be transferred due to a bias voltage in its uncoupled state, preferably automatically transferred. Preferably, the second clutch is decoupled into it Position biased. This can be effected according to the invention, in particular by means of a spring or compression spring.
  • Cylinder holder is relatively positionable. You can especially with a
  • Linear guide for example in the form of a guide rod, relative to
  • Cylinder receiving be positioned positioned in the axial direction.
  • the coupling unit may in particular be designed in the manner or in the form of a carriage.
  • the coupling unit can carry or store the first clutch and the second clutch as well as the possibly existing actuator between the first and the second clutch.
  • the coupling unit can bear or form a bearing, for example in the form of a bearing journal or bearing pin, which serves for a bearing, in particular pivotable mounting, of the coupling element of the first coupling.
  • Swivel lever mechanism operatively connected to the operator-side actuation of the syringe pump. It is in particular positionable by its operator-side operation.
  • the second clutch with the
  • Swing lever mechanism be operatively connected and by the
  • operator-side actuation be positioned in their uncoupling position.
  • An embodiment is characterized in that the drive head has two pivotable clamping elements. These are for clamping the syringe piston and / or the syringe plunger plate provided thereon formed and determined from opposite sides therebetween.
  • the clamping elements are each formed such that one of the respective clamping element on the syringe piston or the
  • Syringe plunger plate exerted clamping force radially to the central longitudinal axis of the
  • the clamping elements may each have a clamping contour whose shape is formed such that contact areas of the clamping elements with the syringes piston or the syringe plunger plate depending on the diameter of the syringe plunger or the syringe plunger plate and the position in the cylinder receiving on diametrically opposite sides of
  • a further embodiment of the invention is characterized in that the cylinder receptacle has a radial fixation for fixing the syringe, in particular the syringe barrel, in the radial direction in the cylinder receptacle.
  • Radial fixing is preferably designed as a radially in the cylinder receiving positionable and in the direction of the cylinder receiving (in a clamping position) biased locking element. It can be positioned in a loading position, that is to say in a position remote from the cylinder receptacle, and in a clamping position, ie in a position close to the cylinder receptacle, and serves in the latter for a syringe located in the cylinder receptacle, in particular by contacting and clamping to fix the syringe barrel.
  • the cylinder receptacle may further comprise a position sensor which detects a proper position and fixation and clamping of the syringe in the cylinder receptacle.
  • a receptacle for syringe wings of the syringe may be formed in the cylinder receptacle, resulting in an additional fixation and securing the position of the syringe in the
  • the drive head to a sensor which detects a contacting of the syringe plunger and the syringe plunger plate with the drive head.
  • the sensor outputs a sensor signal which is used for an immediate, at least as immediate as possible coupling of the drive head to the drive, so that further manual positioning of the drive head relative to the syringe is no longer possible and unintentional bolus administration.
  • the drive head has a pressure plate which is movable relative to the drive head in the axial direction and serves for contacting the syringe plunger plate.
  • the pressure plate can in particular be designed to be elastic, for example as a diaphragm plate.
  • the mobility and / or the elasticity of the pressure plate serves two purposes, on the one hand a contact of pressure plate and syringe plunger plate can be detected simply by a displacement or deformation of the pressure plate, on the other hand, the displaceability and / or elasticity can be designed such that even at a initial light contact, movement of the syringe plunger in the syringe barrel is avoided.
  • the drive unit of the syringe pump consists of a drive, which is preferably formed by an electric motor, and of a gear unit for converting the drive torque of the drive into a drive
  • the transmission unit can be designed in particular as a band transmission in the broadest sense, for example with a toothed belt, a V-belt, a chain drive or a cable, or as a spindle drive with a threaded spindle and a spindle nut.
  • the coupling elements of the first coupling may be formed with particular advantage with a kind of half-shell spindle nut and contact the spindle directly.
  • a coupling or decoupling of the drive and the drive head according to the invention can be effected by direct or indirect action of the coupling unit on the drive.
  • the coupling unit can contact the drive unit formed from drive and gear unit at any point, in particular, a contact can be made for coupling / decoupling of the gear unit.
  • the coupling elements of the coupling unit with the gear unit for example with a toothed belt or a threaded spindle, are engaged and disengaged and lock their movement or release.
  • Syringe plunger plate comes into contact and there is a possibility that the piston relative to the syringe barrel could be relatively positioned, according to the invention is a coupling and thus locking and fixing the position of drive and drive head and thus of syringe plunger and syringe barrel, so that a possible, unwanted drug flow can be safely avoided by the invention.
  • a secure, automatic fixing of the piston plate on the drive head is in particular without causing tilting of the position of the syringe in the
  • Syringe pump which is set up and designed for a basically manual syringe change. After inserting a syringe in the
  • Syringe pump is monitored according to the invention, the forward movement of the drive head and interrupted as soon as a piston plate of the syringe is detected by the drive head.
  • the syringe pump according to the invention further allows an automatic fixation of the piston plate without tilting the piston rod.
  • the manual loading operation can be improved by monitoring the position of the syringe barrel. This ultimately improves safe and quick handling of the infusion syringe pump.
  • FIG. 2 is a schematic enlarged detail view of the coupling unit of the syringe pump
  • FIG. 5 is a schematic plan view of a known fixation for the syringe on a drive head
  • FIG. 6 is a schematic plan view of a fixation for the syringe on a drive head according to the invention
  • Fig. 8 is a schematic representation of a cylinder receptacle and a
  • FIG. 9 is a schematic representation of a cylinder receptacle and a
  • FIG. 10 is a schematic, perspective view of the syringe pump according to the invention without inserted syringe and without housing cover,
  • 1 1 is an enlarged detail view of the actuator unit of Figure 10 without cover
  • 12 is a sectional view of the drive head to illustrate the function of a sensor for detecting a contact of the syringe
  • FIG. 13 is a perspective view of the drive unit, actuator unit and coupling unit
  • Fig. 14 is a perspective view of the drive head
  • Figure 1 shows a schematic representation of an embodiment of
  • the pump 1 comprises a drive unit 3 formed essentially of a drive 4 in the form of an electric motor and a spindle drive 5 with spindle 6 and spindle bearings 7a, 7b. It further comprises a base plate 8, which is a syringe holder or
  • Syringe cylinder receptacle the spindle bearings 7a, 7b and a linear guide 10 carries.
  • the syringe holder 9, the spindle bearings 7a, 7b and the linear guide 10 are each fixed and fixed to each other.
  • the spindle 6 is rotationally driven by the drive 4 and rotatably, but axially fixed by means of the bearing 7 a, 7 b stored.
  • the syringe pump 1 also comprises a coupling unit 1 1, which is guided positionable on the linear guide 10 in the axial direction, and an integrated drive unit 12 in a drive head 13.
  • the drive head 13 is connected via a torque tube or drive tube 14 fixed to the coupling unit 1 1.
  • Drive tube 14 is an actuating or unlocking rod 15 is arranged, via which the actuating unit 12 in a manner described in more detail below with the coupling unit 1 1 is operatively connected.
  • a control 51 for controlling the syringe pump 1 and its components is indicated in FIG.
  • the coupling unit 1 1 is shown schematically and in detail in FIG. It comprises a carriage 16, a first clutch 17, a second clutch 18 and an actuator 19.
  • the second clutch 18 has an electromagnet 20 and is connected to the Actuating or unlocking rod 15 connected / operatively connected.
  • the electromagnet 20 forms a first part of the second clutch 18, which is connected to the
  • Actuator 19 as the second part of the second clutch 18 can be coupled and uncoupled.
  • the first clutch 17 has two coupling elements 21 designed as lever arms 21, which are each mounted rotatably on the carriage 16 by means of a bearing pin 22. At its end opposite to the bearing pin 22 each lever arm 21 is provided with an engagement portion 23. This is in each case by type and form of half
  • Threaded nut or spindle nut 23 is formed for engagement with the threaded spindle 6.
  • the lever arms 21 are each provided with a stop arm 24.
  • the compression spring 25 is with its stop arms 24 opposite end to a sleeve 26 of the actuator 19 in abutment.
  • the compression spring 25 causes the stop arms 24 and the sleeve 26 of the actuator 19 are pressed apart.
  • the compression spring 25 biases the first clutch 17 in its coupled position, in which the spindle half-nuts 23 of the coupling arms 21 with the
  • Threaded spindle 6 are engaged (see Figures 2 and 4).
  • the syringe 2 may be a conventional disposable syringe and consists essentially of a syringe barrel 28 and a syringe plunger 29 displaceable therein in the axial direction, which is provided with a syringe plunger plate 30 on its side opposite the syringe barrel 28.
  • the syringe 2 is more accurate as shown in FIG is shown inserted into the (syringe) cylinder receptacle 9 of the pump 1.
  • the cylinder receptacle 9 is formed with a radial fixation 31 and an axial fixation 32.
  • the syringe barrel 28 is not on its entire length at the
  • Cylinder receiving 9 and the syringe wings 33 are not in the gap 34, so that the sensor 35 indicates no correct position.
  • FIGS. 10 to 14 show, inter alia, the actuating unit 12.
  • This has a housing 36 in which an actuating lever 37 is pivotably mounted about an axis of rotation 38.
  • an actuating lever 37 is pivotably mounted about an axis of rotation 38.
  • the actuating lever 37 is a lever arm 39 or driver 39 formed with an inclined plane
  • Sliding slope 40 of the driver 39 is connected to the actuating or
  • Unlocking rod 15 in Appendix If the driver 39 is in the rest position shown in FIG. 11, the actuating or unlocking rod 15 is displaced in the direction of the driver 39 (see FIG. 1, there to the right). As a result, the electromagnet 20 is also shifted to the left and the second clutch 18 is in its coupled state (state according to FIG. 2). The actuator is located in its end position remote from the bearing pins 22, the compression spring 25 is relaxed and the first clutch 17 engaged, so that the coupling elements 21 are in engagement with the spindle 6, a torque from the drive 4 is transmitted to the drive head 13 and a manual adjustment is not possible.
  • the operating lever 37 can be moved by the user by about 30 ° down (with reference to Figure 1 1). This rotational movement is transmitted via the driver 39 on the actuating or unlocking rod 15 and in such a way
  • the drive head 13 has a sensor 42 which serves to make contact between the drive head 13 and a Spntzenkolbenplatte 30 one in the
  • Cylinder receiving 9 intended to recognize arranged syringe 2.
  • the sensor 42 is shown schematically in FIG. 12 and comprises a fork light barrier 43 with a light source (not shown) and an opposite light sensor (not shown).
  • the drive head 13 further comprises a pressure plate 46, which may be formed as a diaphragm plate 46, for engagement and actuation of the Spntzenkolbenplatte 30, in the axial direction relative to the housing 36 of the
  • Drive head 13 and the actuator unit 12 is movable, e.g. is stored.
  • the pressure plate 46 changes its position in relation to the housing connection in contact with the Spntzenkolbenplatte 30.
  • the drive head still includes a connected via a pin 47 to the pressure plate 46 switching lug 48. This is between
  • Light source and light sensor of the fork light barrier 43 arranged and interrupts the beam path.
  • the beam path is released by the switching flag 48.
  • the light barrier 43 generates a signal as soon as the drive head 13, in this case the pressure plate 46, comes into contact with the Spntzenkolbenplatte.
  • FIG. 15 shows a detail of the cylinder receptacle 9 enlarged in one
  • Cylinder receiving 9 which forms a support surface for the syringe barrel 28. Furthermore, the axial fixation 32 as well as the radial fixation 31 can be seen.
  • Figure 13 shows parts of the drive of Figure 1 in their actual
  • the drive 4 in the form of the electric motor 4 is connected via a gear transmission 50 with the spindle 6 and arranged outside of the axis of the spindle 6. In this way, the axial length of the pump 1 can be made short.
  • the first clutch 17 is shown without the compression spring 25.
  • the drive head 13 is shown in Figure 14 in a perspective view. There, in addition to the pressure plate 46, the housing 36, the drive tube 14 and the unlocking rod 15 two pivotally mounted on the drive head 13 and mounted therein clamping elements 48 are shown.
  • FIG. 4 shows prior art clamping elements 48 and illustrates the formation of a radially acting force F upon clamping a large diameter syringe plunger plate 30a to a small diameter syringe plunger plate 30b.
  • FIG. 6 shows a solution according to the invention with arcuate clamping surfaces 52 of the clamping elements, wherein no radial force is generated independently of the diameter of the respective piston plate 30a, 30b.
  • FIG. 7 shows a flowchart for the process of inserting the syringe 2 into the pump 1.
  • Electromagnet 20 pulls the actuator 19 toward him. At the same time, by the
  • the actuating lever 37 Operation of the actuating lever 37, the actuating rod 15 is displaced in the direction of the drive 4. Since the second clutch 18 is energized, the actuator 19 is displaced against the bias of the compression spring 25 in the direction of the drive 4. The compression spring 25 acts on the actuator 19 side facing away from the
  • a syringe 2 is inserted into the cylinder receptacle 9 so that syringe blades 33 are inserted in the gap 34 between the cylinder receptacle 9 and the axial fixation 32 (see FIG. 8).
  • the position sensor 35 checks the intended location of the syringe 2 in the receptacle 9. In this way it is ensured that the syringe barrel 28 is inserted properly and the syringe axis
  • Syringe plunger plate 30 contacted and the sensor 42 acts in the drive head 13 in the manner described above and gives a signal.
  • the solenoid 20 is de-energized by the control of the pump 1.
  • the second clutch 18 is opened immediately, so that the actuator 19 as a result of the action of the compression spring 25 from the drive 4 moves (in the figures 1 to 4 to the right) and thereby by sliding over the sliding slopes 40 of the coupling arms these from the of the Spindle 6 decoupled position in the coupled with the spindle 6 position urges.
  • the actuator 19 as a result of the action of the compression spring 25 from the drive 4 moves (in the figures 1 to 4 to the right) and thereby by sliding over the sliding slopes 40 of the coupling arms these from the of the Spindle 6 decoupled position in the coupled with the spindle 6 position urges.
  • Drive head 13 is again connected to the drive 4 and can not be moved manually. Another relative displacement of the pressure plate 46 in the direction of the cylinder receptacle 9 and thus a movement of the syringe plunger 29 in
  • the method of Figure 7 includes a special feature that the drive 4 at a signal from the sensor 42 and after coupling with the spindle 6 by a certain distance "backwards" runs and the drive head 13 of the
  • Syringe plunger plate 30 continues to move.
  • the sensor 42 detects a release of the
  • Pressure plate 46 of the syringe plunger plate 30 and then again gives a signal.
  • Drive 4 is then stopped by the pump control and advances by a fixed distance, so that the drive head 13 is moved by this fixed distance in the direction of the syringe plunger plate 30.
  • the clamping arms 48 are closed, so that the syringe plunger plate 30 is fixed to the pressure plate 46.
  • the syringe pump 1 is then ready for application of the medicament contained in the syringe 2.
  • Coupling elements 21 coupled to the threaded spindle 6.
  • the spring 25 is relaxed and the second clutch 18 is open, so uncoupled. This condition of

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  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne une pompe (1) à seringue pour l'administration automatisée de médicaments à partir d'une seringue (2) à un patient, présentant un logement cylindrique (9) pour un cylindre (28) de la seringue (2), une tête d'entraînement (13) pouvant être positionnée par rapport au logement cylindrique (9) pour la mise en contact avec et l'actionnement d'une plaque (30) de piston de la seringue (2), un dispositif d'entraînement (4) pour leur positionnement relatif et une unité d'accouplement (11) à actionner par un utilisateur pour l'accouplement et le désaccouplement du dispositif d'entraînement (4) et de la tête d'entraînement (13). L'unité d'accouplement (11) désaccouple le dispositif d'entraînement (4) et la tête d'entraînement (13) suite à un actionnement par l'utilisateur, de manière telle que la tête d'entraînement (13) peut être positionnée manuellement par rapport au logement cylindrique (9) et s'accouple automatiquement lors d'un contact de la plaque (30) de piston de seringue avec la tête d'entraînement (13, 46). L'invention concerne en outre un procédé pour la mise en place d'une seringue (2) dans une pompe (1) à seringue, en particulier dans une pompe (1) à seringue selon l'invention.
PCT/EP2017/070713 2016-08-23 2017-08-16 Pompe à seringue présentant une procédé amélioré de mise en place de seringues pour éviter des administrations non souhaitées de bolus WO2018036875A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102016115608.6 2016-08-23
DE102016115608.6A DE102016115608A1 (de) 2016-08-23 2016-08-23 Spritzenpumpe mit verbesserter Einlegeprozedur von Spritzen zur Vermeidung ungewollter Bolusgaben

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WO2018036875A1 true WO2018036875A1 (fr) 2018-03-01

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10780235B2 (en) 2012-12-28 2020-09-22 Gambro Lundia Ab Syringe pump engagement detection apparatus and methods
DE102021118221A1 (de) 2021-07-14 2023-01-19 B. Braun Melsungen Aktiengesellschaft Spritzenpumpe und Verfahren zum verbesserten Einlegen einer Spritze

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Publication number Priority date Publication date Assignee Title
EP1723978A2 (fr) * 2002-06-05 2006-11-22 Cardinal Health 303, Inc. Système de propulsion pour des tiges de piston de seringues
WO2011039250A1 (fr) * 2009-10-02 2011-04-07 Fresenius Vial Sas Procede de controle antibolus et dispositif correspondant
WO2013092889A1 (fr) * 2011-12-23 2013-06-27 B. Braun Melsungen Ag Pompe de perfusion pourvue d'un dispositif d'entraînement et appareil de blocage pour la tête d'entraînement de piston d'injection de perfusion
EP2599511B1 (fr) 2011-11-30 2014-08-13 B. Braun Melsungen AG Dispositif d'actionnement pour le déplacement linéaire d'un piston pour seringues à perfusion, pompe à perfusion et procédé de changement d'une seringue à perfusion

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US5034004A (en) 1987-06-19 1991-07-23 The University Of Melbourne Infusion pump and drive systems therefor
DE3739563C1 (de) 1987-11-22 1989-04-13 Fresenius Ag Infusionsspritzenpumpe
JP2717808B2 (ja) 1988-08-10 1998-02-25 テルモ株式会社 シリンジポンプ
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1723978A2 (fr) * 2002-06-05 2006-11-22 Cardinal Health 303, Inc. Système de propulsion pour des tiges de piston de seringues
WO2011039250A1 (fr) * 2009-10-02 2011-04-07 Fresenius Vial Sas Procede de controle antibolus et dispositif correspondant
EP2599511B1 (fr) 2011-11-30 2014-08-13 B. Braun Melsungen AG Dispositif d'actionnement pour le déplacement linéaire d'un piston pour seringues à perfusion, pompe à perfusion et procédé de changement d'une seringue à perfusion
WO2013092889A1 (fr) * 2011-12-23 2013-06-27 B. Braun Melsungen Ag Pompe de perfusion pourvue d'un dispositif d'entraînement et appareil de blocage pour la tête d'entraînement de piston d'injection de perfusion

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10780235B2 (en) 2012-12-28 2020-09-22 Gambro Lundia Ab Syringe pump engagement detection apparatus and methods
DE102021118221A1 (de) 2021-07-14 2023-01-19 B. Braun Melsungen Aktiengesellschaft Spritzenpumpe und Verfahren zum verbesserten Einlegen einer Spritze

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