WO2018001300A1

WO2018001300A1 - Cereal fiber composition and use thereof

Info

Publication number: WO2018001300A1
Application number: PCT/CN2017/090751
Authority: WO
Inventors: 赵立平; 籍刘英; 刘双; 王凌华; 付华清; 胡慰任; 龙文敏
Original assignee: 完美（中国）有限公司
Priority date: 2016-06-29
Filing date: 2017-06-29
Publication date: 2018-01-04
Also published as: CN106234922A

Abstract

Disclosed are a cereal fiber powder composition and a use thereof. The cereal fiber powder composition comprises a cereal fiber powder and one or more prebiotics, wherein the cereal fiber powder is obtained from raw grains in which a part of endosperm is discarded. Also provided are a use of the cereal fiber powder composition for preparing drugs, healthy foods or health-care products for controlling postprandial blood glucose, adjusting intestinal microbial community structure, reducing generation of endotoxin, and/or improving metabolic status of human body.

Description

Cereal fiber powder composition and use thereof

Technical field

The invention belongs to the fields of processing, production and use of medicines, foods and health care products. More specifically, the present invention relates to a cereal fiber powder composition and uses thereof.

Background technique

In recent decades, metabolic diseases such as obesity, insulin resistance and type 2 diabetes have been experiencing an explosive trend worldwide. Studies have shown that structurally imbalanced intestinal flora may be involved in the development and progression of metabolic diseases such as obesity. The unhealthy intestinal flora structure produces endotoxin, which stimulates the body to develop chronic inflammation and gradually produces insulin resistance, leading to the occurrence of chronic diseases such as diabetes and obesity.

Diet can shape the structure of the intestinal flora, but as people's living standards improve, the food they eat becomes more and more "fine." In particular, as a staple food of cereals, due to the excessive processing of raw grains, nutrients such as dietary fiber and minerals, which are beneficial to human and intestinal bacteria, are largely lost. These foods produced by over-processed food are digested and absorbed by the human body in the small intestine, causing blood sugar to rise rapidly, and the intestinal bacteria in the large intestine cannot obtain nutrients from the food that can support the beneficial bacteria, resulting in endotoxin production. The number of harmful bacteria has increased.

Dietary fiber is a nutrient that is indigestible to the human body and thus can enter the large intestine and act directly on intestinal bacteria. Dietary fiber provides a substrate for enteric beneficial bacteria that produce short-chain fatty acids and hydrogen. There have been many studies showing that short-chain fatty acids are beneficial to human health; hydrogen has antioxidant properties and can selectively scavenge hydroxyl radicals and nitrite groups, which have a positive effect on human health (Supplementation of hydrogen-rich water stimulate lipid and glucose) Metabolism in patients with type 2 diabetes or impaired glucose tolerance;Sizuo Kajiyama;Nutrition Research 28(2008)137–143;Hydrogen-rich water finding serum low-density lipoprotein cholesterol levels and improves high-density lipoprotein function in patients with potential metabolic syndrome ; Guohua Song; Journal of Lipid Research; June 1, 2015). Based on these latest research results, people have gradually formed a new concept of nutrition, which is to provide sufficient nutrient substrate for the intestinal flora while meeting the nutritional needs of the human body. Food research and development has also begun to focus on ways to reduce or slow down the digestion and absorption of carbohydrates, allowing dietary fiber in foods to function in the large intestine and colon.

Most of the products currently used in the market to slow down the digestion and absorption of carbohydrates mainly use resistant starch or prebiotics, which have a single nutrient composition and cannot meet the comprehensive nutrition required by the human body. Therefore, there is still a need in the art for a healthy food that is both nutritious and rich in dietary fiber.

Summary of the invention

According to a first aspect of the invention, there is provided a cereal fiber powder composition, the composition comprising:

Cereal fiber powder, which is a cereal fiber powder obtained by discarding part of the endosperm from the grain raw grain;

One or more prebiotics.

In one embodiment, the discarded part of the endosperm accounts for more than 50%, 51%, more than 52%, more than 53%, more than 54%, more than 55%, more than 56%, more than 57%, 58 of the total grain weight of the grain. % or more, 59% or more, 60% or more, 65% or more, 70% or more, 75% or more, or 79% or more. In one embodiment, the discarded part of the endosperm accounts for 80% or less, 75% or less, 70% or less, 65% or less, 60% or less, 59% or less, 58% or less, 57% or less, 56% of the total weight of the grain raw grain. % or less, 55% or less, 54% or less, 53% or less, 52% or less, or 51% or less. In one embodiment, the discarded endosperm comprises 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 65 of the total weight of the grain raw grain. %, 70%, 75%, or 80%. Preferably, the discarded endosperm comprises 60-80% of the total weight of the grain raw grain. More preferably, the discarded endosperm comprises 60-70% of the total weight of the grain raw grain.

In one embodiment, the cereal fiber powder comprises the epidermis, peel, seed coat, bead layer, aleurone layer, germ and part of the endosperm of the grain, and the retained part of the endosperm does not exceed 60%, 55%, 50 of the weight of the grain fiber powder. %, 45%, 40%, 35%, 30% or 25%.

In one embodiment, the prebiotic comprises oligosaccharides, polysaccharides, plant herbal extracts, protein hydrolysates, polyols. In one embodiment, the prebiotic is selected from the group consisting of inulin, oligosaccharides, and resistant dextrin. In one embodiment, the oligosaccharides include, but are not limited to, oligofructose and xylooligosaccharides. In a preferred embodiment, the prebiotic comprises inulin, oligofructose, xylooligosaccharide, and resistant dextrin.

In one embodiment, the prebiotic comprises 10% or more, or 15% or more, and 30% or less, 25% or less, or 20% or less, based on the total weight of the cereal fiber powder composition.

In one embodiment, the cereal fiber powder composition further comprises konjac flour. In one embodiment, the konjac flour comprises from 3-5% by weight of the total weight of the cereal fiber powder composition.

In one embodiment, the cereal fiber powder is prepared by the following method:

(1) crushing and grinding the grain raw grain and discarding part of the endosperm in the grain raw grain;

(2) The retained portion is subjected to secondary grinding and sieving to obtain a cereal fiber powder.

In one embodiment, part of the endosperm discarded in the step (1) accounts for more than 50%, 51% or more, 52% or more, 53% or more, 54% or more, 55% or more, 56% or more of the total grain weight of the grain. 57% or more, 58% or more, 59% or more, 60% or more, 65% or more, 70% or more, 75% or more, or 79% or more. In one embodiment, the discarded part of the endosperm accounts for 80% or less, 75% or less, 70% or less, 65% or less, 60% or less, 59% or less, 58% or less, 57% or less, 56% of the total weight of the grain raw grain. % or less, 55% or less, 54% or less, 53% or less, 52% or less, or 51% or less. In one embodiment, the endosperm discarded in step (1) accounts for 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59% of the total weight of the grain raw grain. 60%, 65%, 70%, 75%, or 80%. Preferably, the endosperm discarded in step (1) comprises 60-80% of the total weight of the grain raw grain. More preferably, the endosperm discarded in step (1) accounts for 60-70% of the total weight of the grain raw grain.

In one embodiment, the fineness of the cereal fiber powder collected in the step (2) is 70 mesh or more, 75 mesh or more, 80 mesh or more, 85 mesh or more, 90 mesh or more, 95 mesh or more, 100 mesh or more, 105 mesh. Above, 110 mesh or more, 115 mesh or more, or 119 mesh or more. In one embodiment, the fineness of the cereal fiber powder is 120 mesh or less, 115 mesh or less, 110 mesh or less, 105 mesh or less, 100 mesh or less, 95 mesh or less, 90 mesh or less, 85 mesh or less, 80 mesh or less, and 75 mesh. Below the target, or below 71 mesh. In one embodiment, the fineness of the cereal fiber powder collected in the step (2) is 70 mesh, 75 mesh, 80 mesh, 85 mesh, 90 mesh, 95 mesh, 100 mesh, 105 mesh, 110 mesh, 115 mesh, Or 120 mesh. Preferably, the grain fiber powder collected in the step (2) has a fineness of 90 to 120 mesh, more preferably 100 to 120 mesh. In one embodiment, the yield of the cereal fiber powder in the step (2) is 75% or more, 80% or more, 85% or more, 90% or more, or 95% or more by weight of the retained portion.

In one embodiment, the grain raw grain is subjected to pulverization grinding and secondary grinding using a pulverizing machine in the step (1), wherein the pulverizing machine is graphite, steel mill or the like.

In one embodiment, the grain raw grain is selected from one or more of the group consisting of Triticum, Hordeum, Avena, Fagopyrum Mill, and Secale. In a preferred embodiment, the cereal grain is selected from the group consisting of Triticum. In one embodiment, the wheat genus grain is selected from the group consisting of common wheat (Triticum aestivum L) and/or Triticum durum. In one embodiment, the barley grain is selected from the group consisting of barley (Hordeum vulgare L.) and/or barley (Hordeum vulgare Linn. var. nudum Hook. f.). In one embodiment, the oat grain is selected from the group consisting of oats (Avena sativa L.) and/or buckwheat (Avena nuda L.). In one embodiment, the buckwheat plant is selected from the group consisting of Fagopyrum esculentum Moench and/or Fagopyrum tataricum (L.) Gaertn. In one embodiment, the rye grain is selected from the group consisting of rye (Secale cereale) L.).

In one embodiment, the cereal fiber powder contains 10-30 grams of dietary fiber per 100 grams, 35-70 grams of carbohydrates, and 10-25 grams of protein.

In one embodiment, the cereal fiber flour or cereal fiber powder composition is cooked or puffed.

In one embodiment, the grain fiber powder is equivalent to the energy produced by the equal weight flour. In one embodiment, the postprandial blood glucose and hydrogen production provided by the cereal fiber powder is comparable to an equal weight of prebiotics such as oligofructose, resistant dextrin, and the like.

In a second aspect of the invention, there is provided the use of the cereal fiber powder composition of the invention as a medicament, health food or health food. In one embodiment, the medicament, health food or health food is used as a meal replacement or a meal. In one embodiment, the medicament, health food or health food is suitable for use in a healthy population, or a subject suffering from obesity, diabetes, metabolic syndrome, or intestinal flora disorders. In one embodiment, the medicament, health food or health food is used to control postprandial blood glucose, adjust intestinal flora structure, reduce endotoxin production, and/or improve body metabolic status. When used as a meal replacement or a meal, the cereal fiber powder composition of the present invention is capable of providing sufficient energy, more comprehensive nutrition, lower postprandial blood glucose levels, and a large amount of hydrogen which is beneficial to the human body in the body. In one embodiment, the cereal fiber powder composition can be consumed directly without further processing, such as cooking. In one embodiment, after the subject consumes the cereal fiber powder composition, its blood glucose level continues to be steadily maintained at a very low level, accompanied by a large amount of hydrogen production beneficial to the human body.

The invention has at least the following advantages:

The cereal fiber powder composition of the invention retains the dietary fiber, minerals, vitamins and other nutrients of the original grain to the greatest extent, and improves the proportion of dietary fiber in the food while satisfying the energy demand and nutritional requirements of the human body; The addition of the prebiotic further enhances the effect of the cereal fiber powder composition of the present invention in regulating the structure of the intestinal flora, reducing the production of endotoxin, and improving the metabolic state of the body. Compared with the general prebiotic product, the cereal fiber powder composition of the invention has richer nutrition, can provide the energy required by the human body, and can provide a comparable or better intestinal in the case of greatly reduced manufacturing time and cost. Improvement of the flora and improvement of body metabolism.

DRAWINGS

1 shows postprandial blood glucose results of a subject after taking a cereal fiber powder composition according to an embodiment of the present invention.

2 illustrates a hydrogen production knot of a cereal fiber powder composition in a subject according to an embodiment of the present invention. fruit.

Figure 3 shows a comparison of postprandial blood glucose of a cereal fiber powder composition with individual cereal fiber powders and individual common prebiotics in accordance with an embodiment of the present invention.

Figure 4 shows a comparison of the area under the hydrogen production curve (AUC) of a cereal fiber powder composition according to an embodiment of the present invention with individual cereal fiber powders and individual common prebiotics.

Figure 5 shows a comparison of the in vivo hydrogen production process of a cereal fiber powder composition and a separate cereal fiber powder in accordance with an embodiment of the present invention.

detailed description

The invention is further described in detail below with reference to the specific embodiments, which are to be understood by those skilled in the art, and are not intended to limit the invention. Unless otherwise stated, all scientific and technical terms used herein have the meaning commonly understood by one of ordinary skill in the art to which the invention belongs. Unless otherwise stated, the ratio refers to the weight ratio and the weight is calculated by dry weight.

The invention is guided by the latest concept of nutrition, that is, the food must satisfy the nutritional needs of the human body as well as the nutritional needs of the intestinal bacteria. The cereal fiber powder composition of the present invention contains a high proportion of dietary fiber. These dietary fibers cannot be decomposed by the human glycosidase after consumption, and thus cannot be absorbed by the human body. This aspect can reduce the postprandial blood glucose load, and on the other hand, is not decomposed. The dietary fiber enters the large intestine and becomes a substrate for intestinal bacterial fermentation. After fermentation, it produces metabolites such as hydrogen and short-chain fatty acids.

The cereal fiber powder composition provided by the present invention comprises:

One or more prebiotics.

In one embodiment, a portion of the endosperm discarded from the grain raw grain comprises from 50% to 80%, such as from 60% to 80% or from 60% to 70%, by total weight of the grain.

In one embodiment, the cereal fiber powder comprises the epidermis, peel, seed coat, bead layer, aleurone layer, germ and part of the endosperm of the grain, and the retained part of the endosperm does not exceed 55%, 50%, 45 of the weight of the grain fiber powder. %, 40%, 35%, 30% or 25%. In order to better control postprandial blood glucose, improve intestinal health, improve body metabolism, etc. in sub-health populations and diabetic patients, it is necessary to reduce the proportion of endosperm in cereal fiber powder, so that the obtained cereal fiber powder has a higher Dietary fiber ratio. In addition, because a small amount of endosperm is retained, a certain proportion of carbohydrates in the grain fiber powder is ensured. Products that remove most of the endosperm are also beneficial for long-term intestinal flora balance and metabolic improvement in healthy people.

The cereal fiber powder of the present invention is rich in plant protein and dietary fiber while retaining the minerals and vitamins in the food to the utmost extent. In one embodiment, the cereal fiber powder of the present invention contains 10-30 grams of dietary fiber per 100 grams, 35-70 grams of carbohydrates, and 10-25 grams of protein.

Prebiotics are non-digestible food ingredients that have a beneficial effect on the human body by selectively stimulating the growth and activity of one or a few bacteria. Prebiotics include dietary fiber. The prebiotics in the present invention include oligosaccharides, polysaccharides, plant herbal extracts, protein hydrolysates, polyols and the like. Any prebiotic can be suitably used in the present invention, and for example, prebiotics that can be used include, but are not limited to, inulin, oligosaccharides, resistant dextrin, and the like. Oligosaccharides include, but are not limited to, oligofructose and/or xylooligosaccharides. In one embodiment, the cereal fiber powder composition of the present invention comprises one or more prebiotics selected from the group consisting of inulin, oligofructose, xylooligosaccharide, and resistant dextrin. The proportion of prebiotics in the cereal fiber powder composition can be reasonably determined by those skilled in the art. In one embodiment, the prebiotic comprises from 10% to 30%, such as from 15% to 25%, by total weight of the cereal fiber powder composition. Since the cereal fiber powder of the present invention contains a large amount of dietary fiber, the hydrogen production in the fermentation is comparable to that of the prebiotic, and thus the proportion of the prebiotic in the cereal fiber powder composition can be reduced to save production time and cost. However, the addition of prebiotics can enrich the variety of dietary fiber to a certain extent, and better improve the distribution of intestinal flora, thereby improving the body's metabolic status.

The cereal fiber powder composition of the present invention may further comprise konjak flour, which may be in the form of a thickening or suspending agent when consumed. The weight ratio of konjac flour in the cereal fiber powder composition may be 3-5%, such as 3%, 4%, 5%, and may be specifically adjusted as needed.

The cereal fiber powder in the cereal cellulose composition of the present invention is prepared by the following method, which comprises the steps of:

(1) crushing and grinding the grain raw grain and discarding the endosperm which accounts for 50-80% of the weight of the grain raw grain;

As used herein, the term "cereal grain" refers to a grain of fruit that has only been removed from the outer shell of the mature grain. For example, in the case where the grain raw grain of the present invention is wheat, the grain raw grain refers to a grain which only removes the outer shell of the wheat without other processing, and thus includes all components of the wheat fruit, such as the epidermis, the peel, the seed coat, and the bead layer. , aleurone layer, germ and endosperm, etc. In the grain granules, in the case of wheat, the proportion of endosperm is as high as about 80%, and the flour we usually refer to is basically the endosperm part. Flour usually contains a lot of carbohydrates, almost no dietary fiber and fat, and low protein content. The portion of the grain granules other than the endosperm is usually present in the bran powder, usually used as a feed, or incorporated into flour to make whole wheat flour.

In the method, most of the endosperm is discarded in step (1) to increase the obtained cereal fiber powder. The proportion of dietary fiber.

In the method of the present invention, the fineness of the cereal fiber powder collected in the step (2) is from 70 mesh to 120 mesh. Because cereal fiber powder contains more dietary fiber, it has a thicker taste and slower digestion, so it should be made into a fine powder state. Further, when the powder is fine, the cereal fiber powder of the present invention can be directly taken without cooking. However, the higher the mesh number, the more time and energy consumption in the processing process will increase. The inventors of the present invention found that when the cereal fiber powder reaches 80 mesh, it can be conveniently taken without causing discomfort to the stomach; when the cereal fiber powder reaches 100 mesh or more, the mouthfeel is better.

In the method of the present invention, the yield of the cereal fiber powder in the step (2) accounts for 75% or more, 80% or more, 85% or more, 90% or more or 95% or more of the weight of the retained portion. Theoretically, the higher the yield of cereal fiber powder, the better, but as the grinding progresses, the abrasive is less and less, and the later the fiber, the higher the fiber content in the remaining abrasive, so the grinding efficiency gradually Go low. Therefore, when the yield is 75% or more, 80% or more, 85% or more, 90% or more, or 95% or more, the grinding can be stopped as needed.

In the process of the invention, comminution milling and secondary milling can be carried out using any suitable means. For example, grinding can be carried out using any suitable comminuting machine, such as stone grinding or steel grinding. An exemplary stone mill that can be used in the present invention is the Dengfeng brand 6F-40 roller mill produced by Shandong Lishui Xinfeng Flour Machinery Co., Ltd., an exemplary steel mill is Shandong Lishui Xinfeng Flour Machinery Co., Ltd. The company's Dengfeng brand 6F-38 roller mill. Specifically, in the practice of the method of the present invention, the grain raw grain may be ground and pulverized by a pulverizing machine such as stone grinding, steel grinding, etc., and a part of the endosperm flour is separately collected and used, and the remaining parts of different fineness are all collected, and then carried out. Secondary grinding and sieving, it is required to obtain a certain degree of fineness. The fiber powder that does not meet the fineness requirement continues to recover the grinding powder. After the yield of the fiber powder meeting the fineness requirement reaches a certain ratio, all the fibers that have reached the fineness are collected. Powder and mix.

In the method of the present invention, the grain raw grain used is not particularly limited, and in one embodiment, the grain raw grain is selected from one or more of the group consisting of Triticum, Hordeum, Oats, Buckwheat, and Rye. . In a preferred embodiment, the cereal grain is selected from the group consisting of Triticum. In one embodiment, the wheat genus grain is selected from the group consisting of common wheat and/or durum wheat. In one embodiment, the barley grain is selected from the group consisting of barley and/or barley. In one embodiment, the oat grain is selected from the group consisting of oats and/or buckwheat. In one embodiment, the buckwheat plant is selected from the group consisting of buckwheat and/or bitter buckwheat. In one embodiment, the rye grain is selected from the group consisting of rye. The type of grain raw grain can be varied and matched according to needs and actual availability. The method of the invention can also be readily applied to any other suitable cereal species by those skilled in the art.

In one embodiment, the cereal fiber powder is aged. In one embodiment, the cereal fiber powder composition is aged. In one embodiment, the cereal fiber flour or cereal fiber powder composition is inflated Chemical. Curing is a commonly used food processing process, and the cereal fiber powder of the present invention or the cereal fiber powder composition to which the prebiotic and/or konjak powder is added may be cooked by any suitable means such as frying, pressing, cooking, and the like. Puffing refers to the use of frying, extrusion, frying, baking, microwave, gas flow and carbon dioxide as a curing process, so that the food has a significant increase in volume before and after the ripening process. The puffing method usable in the present invention is not limited, but for the sake of healthy eating, it is preferred to use a non-fried puffing method such as extrusion, microwave, air flow, and carbon expansion. Although ripening and puffing increase the mouthfeel of the cereal fiber powder composition and prolong its shelf life, if the ripening and puffing are carried out for too long, the dietary fiber in the composition may be destroyed. Therefore, it is preferred to carry out moderate ripening or puffing in a short period of time to protect the digestible properties of the dietary fiber as much as possible.

The cereal fiber powder composition of the invention contains a large amount of dietary fiber, and thus can be used as a medicine, a health food or a health food to regulate or improve the intestinal flora (supporting beneficial bacteria, inhibiting harmful bacteria), increasing hydrogen production, and improving body metabolism. Status, control of the role of postprandial blood glucose. Further, since the cereal fiber powder composition of the present invention can provide energy equivalent to that of an equal weight flour, it can be used as a meal replacement or a meal. By simply taking the meal replacement or accompanying meal of the present invention, it is possible to simultaneously replenish energy and maintain health. The term "meal meal" as used herein refers to replacing all or part of a meal. As used herein, "meal" refers to taking with a meal.

Since the grain fiber powder in the grain fiber powder composition itself contains a large amount of dietary fiber, a so-called prebiotic, it can support or improve the growth of beneficial bacteria in the intestine. Therefore, only a small amount of prebiotics need to be supplemented. Supplementation of additional prebiotics can enrich the types of nutrients to a certain extent and better improve the growth of beneficial intestinal flora. In addition, since the production process of the cereal fiber powder of the present invention is relatively simple, the cost is low, and the nutrition is more comprehensive, the composition of the present invention has certain advantages over the general prebiotic product.

The cereal fiber powder composition of the present invention is suitable for use in healthy people as a medicine, health food or health food, and is also suitable for patients suffering from obesity, diabetes, metabolic syndrome, or intestinal flora imbalance. Both can improve the intestinal energy flora and improve the body's metabolism while meeting the energy needs and nutritional needs of the human body.

The present invention reflects the fermentation of food in the intestine by detecting hydrogen in the exhaled gas in a subject ingesting food. The fermentation of indigestible microorganisms to non-digestible food components is the only way to produce hydrogen in the human body. This part of the exhaled hydrogen is combined with methane for the detection of excessive proliferation of intestinal bacteria.

The terms "including" and "comprising" are used interchangeably and in the context of the present application. Covered the expression "consisting of".

The invention will now be further elucidated in connection with specific embodiments. It is to be understood that the examples are merely illustrative of the invention and are not intended to limit the scope of the invention. The scope of the invention is to be limited only by the appended claims. A person skilled in the art can make various changes and modifications to the invention without departing from the spirit and scope of the invention, and the modifications and variations are considered to be equivalents of the embodiments of the invention. It is within the scope of the invention. It should also be noted that various and various features described in the context of the present application can be combined freely and are not limited to the specific embodiments.

Example

Example 1 Production of Dryland Wheat Fiber Powder

The dry wheat wheat raw material purchased from Hongdong County Zhongyi Agricultural Development Co., Ltd. was pulverized and ground using Dengfeng Brand 6F-40 Roller Stone Mill or 6F-38 Roller Steel Mill produced by Shandong Lishui Xinfeng Flour Machinery Co., Ltd. Dryland wheat refers to wheat planted in hilly land and hillsides in arid and semi-arid areas, and cultivated by natural precipitation. The planting area of dryland wheat used in this example is in some hilly land and hillsides in Hongdong County, Shanxi Province. . In the above pulverization grinding, the vertical grinding disc is selected, which greatly reduces the ash in the flour. The stone mill rotates at 20 rpm, the temperature is 45 degrees, and this kind of heart-and-weight milling process greatly reduces the number of wheat in the grinding, the aroma of wheat germ, protein, carotene, carbohydrate, calcium. Nutrients such as phosphorus, iron, vitamin B1, vitamin B2 and dietary fiber are completely retained. After the pulverization and grinding, the endosperm which accounts for 65% by weight of the dry wheat raw grain is separately collected. All the bran powders with different fineness of 35% of the weight of the dry wheat wheat raw grain were collected and further ground, that is, secondary grinding. The gluten powder with a fineness of 100-120 mesh is collected by sieving, and the powder which does not meet the fineness requirement is put back into the ink and re-grinded until the fiber powder having the fineness requirement in the 35% bran powder reaches 85%, and stops. Grinding. The fiber powder that meets the fineness requirement is mixed and collected for use, and the remaining part is discarded.

Example 2 Determination of energy and main nutrients in dryland wheat fiber powder

The energy and major nutrient content of the obtained wheat fiber powder were measured according to standard methods. Energy and carbohydrates were tested according to GB/T 21922-2008; protein, fat and dietary fiber powders were tested according to GB 5009.5-2010 first method, GB/T 5009.6-2003 acid hydrolysis method and AOAC 991.43.

The main nutrient contents of the wheat fiber powder prepared and tested according to the above method are shown in Table 1 below. Compared with common dry wheat flour, dietary fiber (wheat fiber powder 23.7g vs. common wheat flour 2.1g) and protein (wheat fiber powder 16.2g vs. common wheat flour 11.2g) increased significantly, while carbohydrate (wheat fiber) The content of powder 50.4g vs. ordinary wheat flour 73.6g) was greatly reduced. At the same time, the same weight of wheat fiber powder provides comparable energy to ordinary wheat flour.

Table 1. Comparison of energy and major nutrients in dryland wheat fiber flour and common wheat flour

项目project	旱地小麦纤维粉(/100g)Dryland wheat fiber powder (/100g)	普通小麦面粉(/100g)Common wheat flour (/100g)
能量energy	1455千焦1455 kJ	1439千焦1439 kJ
蛋白质protein	16.2g16.2g	11.2g11.2g
脂肪fat	3.6g3.6g	1.5g1.5g
碳水化合物Carbohydrate	50.4g50.4g	71.5g71.5g
膳食纤维Dietary fiber	23.7g23.7g	2.1g2.1g

Data source: a, Standards Technical Service (Shanghai) Co., Ltd. testing; b, China Food Ingredients Table, Wang Guangya, 2010; the carbohydrates in the above table do not include dietary fiber components.

Example 3 Preparation of cereal fiber powder composition and postprandial blood glucose and hydrogen production test

A cereal fiber powder composition was prepared according to the formulation of Table 2.

Table 2 Formula of cereal fiber powder composition

Four healthy subjects (no abnormal glucose tolerance) were banned from eating after 8 pm the day before the test, and 20 g of the cereal fiber powder composition prepared above was taken on an empty stomach for breakfast, and no more food was consumed until the end of the test. When taking the composition, the method of consumption can be adjusted according to personal preference, and can be made into a wheat paste drink by using 300 mL of warm water, or can be made into a milk tea-like beverage by using 500 mL of warm water. Eating ends in 5 minutes. As a control, a 45-year-old healthy man with a BMI of 22.3 had no glucose tolerance and was fed 20 g of white rice in the same manner.

The increase in postprandial blood glucose was measured in the subjects, showing the mean value of the test for 4 subjects. Test method: Roche Performa (using Roche blood glucose meter)

Performa) was monitored on an empty stomach (0 min), 30 min after eating (after eating, the first time after eating), 60 min, 120 min, and 180 min.

The condition in which hydrogen was produced after the meal of the subject was examined, and the average value of the test of the four subjects was shown. Gas was collected on the fasting day at 0 o'clock on the morning of the test. Gas was collected every hour after eating the test product, and the hydrogen content was detected by the US QUINTRON BreathTracker Breathing Gas Detector.

Fig. 1 and Fig. 2 respectively show the results of comparison of postprandial blood glucose and the results of hydrogen production of the cereal fiber powder composition of Example 3 and white rice.

As shown in Fig. 1, the cereal fiber powder composition prepared above had a smooth postprandial blood glucose with a peak value of 6.0 mmol/L, indicating that the composition did not increase the blood sugar load. In the control subjects, after eating white rice, the postprandial blood glucose rapidly increased to about 11 mmol/L.

As shown in Fig. 2, the composition has the advantages of a high hydrogen production peak (greater than 40 ppm) and a long hydrogen production duration (360 min), indicating that the composition effectively enriches the hydrogen-producing bacteria in the intestinal tract. The white rice of the control group produced almost no hydrogen.

Example 4. Cereal fiber powder composition with separate grain fiber powder and separate common prebiotic meal Comparison of post-blood glucose and hydrogen production

Referring to the procedure in Example 3, a total of 4 healthy subjects (age 28-45 years old, BMI 18.0-22.3, abnormal glucose tolerance) were involved in the comparison of dry wheat fiber powder and common prebiotics in the dryland. Hour, collect the fasting exhaled hydrogen before the test on the day of the test, measure the fasting blood glucose, and test the blood sugar level within 3 hours after the meal, and detect the hydrogen production within 12 hours after the meal, every 60 minutes. Eat again after the test. The four healthy subjects participated in two or three rounds of testing, and the two rounds were separated by several days. Among them, one subject took 20 g of the dryland wheat fiber powder prepared in Example 1 in the first round test, and took 20 g of inulin in the second round test (manufactured by Wuhan Yingnuolin Biotechnology Co., Ltd.); The tester took 20 g of resistant dextrin (Fibersol-2, manufactured by MATSUTANI Chemical Industry Co., Ltd.) in the first round test, and took 20 g of fructooligosaccharide (QHT-FOS-P95S, Olydo in the second round test).

Quantum Hi-Tech (China) Co., Ltd.); 1 subject took 20g of xylooligosaccharide (made by Shandong Longli Biotechnology Co., Ltd.) in the first round of testing, and took 20g of konjac in the second round of testing (Mianyang Shengan Konjac Products Co., Ltd., Sichuan); another subject took 20g of white rice in the first round of testing, and took 20g of the cereal fiber powder composition of Example 3 in the second round of testing. No food was taken in the 3 rounds to measure the fasting hydrogen production.

Figure 3 shows a comparison of the postprandial blood glucose of the dryland wheat fiber powder composition of Example 3 with the dry wheat fiber powder of Example 1 and several common prebiotics. As shown in Fig. 3, the postprandial blood glucose AUC (area under the curve) of the dryland wheat fiber powder composition is the same as that of the dry wheat fiber powder of Example 1 and several common prebiotics. Resistant dextrin and oligofructose are basically the same, both kept at a low level and much lower than white rice.

Figure 4 is a graph showing the comparison of the post-apartment hydrogen production AUC of the dry wheat fiber powder composition of Example 3 with the dry wheat fiber powder of Example 1 and several common prebiotics. As shown in Fig. 4, the postprandial hydrogen production of the dryland wheat fiber powder composition is comparable to that of the individual cereal fiber powder and several common prebiotics such as oligofructose, which is lower than that of inulin and much higher than that of white rice.

Table 3 specifically compares the post-prandial hydrogen production of the dry wheat fiber powder composition of Example 3 with the dry wheat fiber powder of Example 1 and several common prebiotics.

Table 3. Mean time-division hydrogen production of cereal fiber powder compositions and cereal fiber powders and common prebiotics

As can be seen from Table 3, inulin produced hydrogen quickly and peaked, and most of the other prebiotics produced hydrogen faster than the dryland wheat fiber powder composition of Example 3 and the dryland wheat fiber powder of Example 1, possibly because of benefits. The structure of the raw element is relatively simple, and it enters the intestine faster for microbial fermentation.

Figure 5 is a graph showing the hydrogen production comparison between the dry wheat fiber powder composition of Example 3 and the dry wheat fiber powder of Example 1. It can be seen from the figure that the peak of hydrogen production in the dry wheat fiber powder composition is larger and the peak appears earlier; while in the first embodiment, the hydrogen production of the dry wheat fiber powder is milder and gentler, and the hydrogen production lasts longer. This may be because the structure of several common prebiotics added to the composition is simpler than that of dry wheat fiber powder, and it enters the intestine faster for microbial fermentation, and because of the addition of prebiotics, the dietary fiber type is more abundant and can be More types of microbial fermentation use, higher hydrogen production peaks appear earlier.

Claims

A cereal fiber powder composition comprising:

Cereal fiber powder, which is a cereal fiber powder obtained by discarding part of the endosperm from the grain raw grain;

One or more prebiotics.
The cereal fiber powder composition according to claim 1, wherein the part of the endosperm accounts for 50-80% by weight of the grain raw grain.
The cereal fiber powder composition according to claim 1, wherein the prebiotic is selected from the group consisting of inulin, oligosaccharides, and resistant dextrin.
The cereal fiber powder composition according to claim 3, wherein the oligosaccharide is selected from the group consisting of oligofructose and/or xylooligosaccharide.
The cereal fiber powder composition according to claim 1, wherein the prebiotic comprises 10-30% by weight based on the total weight of the cereal fiber powder composition.
The cereal fiber powder composition according to claim 1, wherein the cereal fiber powder composition further comprises konjac flour.
The cereal fiber powder composition according to claim 6, wherein the konjac flour comprises from 3 to 5% by weight based on the total weight of the cereal fiber powder composition.
The cereal fiber powder composition according to any one of claims 1 to 7, wherein the cereal fiber powder is prepared by the following method:

(1) crushing and grinding the grain raw grain and discarding part of the endosperm, the part of the endosperm accounting for 50-80% of the weight of the grain raw grain;

(2) The retained portion is subjected to secondary grinding and sieving to obtain a cereal fiber powder having a fineness of 70-120 mesh.
The cereal fiber powder composition according to claim 7, wherein the grain raw grain is selected from one or more of the group consisting of Triticum, Hordeum, Oats, Buckwheat, and Rye.
The cereal fiber powder composition according to claim 1, wherein the cereal fiber powder or the cereal fiber powder composition is cooked or expanded.
A cereal fiber powder composition according to any one of claims 1 to 10 for use as a medicament for the preparation of postprandial blood glucose, for adjusting the structure of the intestinal flora, for reducing endotoxin production, and/or for improving the metabolism of the body, or a health food or The use of health foods.
The use according to claim 11, wherein the medicine, the health food or the health food is used as a meal replacement or a meal.