WO2017219838A1 - Émulsion antimoustique - Google Patents

Émulsion antimoustique Download PDF

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Publication number
WO2017219838A1
WO2017219838A1 PCT/CN2017/086766 CN2017086766W WO2017219838A1 WO 2017219838 A1 WO2017219838 A1 WO 2017219838A1 CN 2017086766 W CN2017086766 W CN 2017086766W WO 2017219838 A1 WO2017219838 A1 WO 2017219838A1
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parts
component
mixture
mosquito
ingredient
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PCT/CN2017/086766
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English (en)
Chinese (zh)
Inventor
吴克
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江苏奇力康皮肤药业有限公司
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Publication of WO2017219838A1 publication Critical patent/WO2017219838A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • the present invention relates to a functional emulsion. More specifically, the present invention relates to an anti-mosquito emulsion.
  • Mosquito belonging to the insect family Diptera, is a small flying insect with a sucking mouthpart. Usually the female uses blood as food, while the male uses the juice of the plant. Blood-sucking female mosquitoes are intermediate hosts for various pathogens such as dengue fever, malaria, yellow fever, filariasis, and Japanese encephalitis. On the earth, except for Antarctica, there are mosquitoes in all other continents.
  • mosquitoes like to bite people with weak acidity. After being bitten by a mosquito, the human skin usually has redness, itching, pain and other symptoms. People with poor skin texture may have more serious symptoms, such as: local itching; small red papules appear; scars appear, ie smooth, bulging Reddened skin or hard swelling.
  • Summer is the best time for breeding of blood-sucking animals such as mosquitoes. It has a strong reproductive and reproductive capacity in summer, and in summer, people have more outdoor activities, and most of them are thin, especially the limbs are often exposed. It is common to be bitten by mosquitoes in summer. ,very common. Anti-mosquito bites appear to be necessary.
  • mosquito repellent drugs sold on the market are made of chemical components, which not only have certain side effects, but also cause pollution to the environment. When they reach the effect of killing mosquitoes, they also pose harm to people, especially The human respiratory tract constitutes an adverse effect. The better the insecticidal effect of this chemical, the more side effects it has, and it is not easy to use it in large quantities.
  • toilet water although it consists only of traditional Chinese medicine and spices, it has a certain effect on mosquito repellent, but its volatility is strong, its persistence is short, and the skin permeability after use is poor, so it needs to be cleaned in time.
  • the invention of Chinese Patent No. CN102018004A discloses a multi-effect mosquito repellent syrup which is composed of a mixture of aerobic amine, citronella oil, amine leaf oil, tea tree oil, pyrethrum vinegar and Litsea cubeba oil.
  • the invention has long anti-mosquito action and has the functions of sterilization, disinfection and air purification, but has poor durability and needs to be applied multiple times.
  • the invention of Chinese Patent No. CN102579288A discloses a direct-acting natural plant essential oil composition for mosquito repellent.
  • Oil lavender oil, wintergreen oil, peppermint oil, cinnamon oil, cedar oil, white orchid oil, musk oil, rose oil, tea tree oil, the technical solution has a complicated source of raw materials, high cost, and the total efficiency of mosquito repellent is not as significant as the present invention.
  • anti-mosquito agents are used as anti-mosquito functions as functional products on the skin surface.
  • the skin comfort is not considered.
  • the skin tends to have poor air permeability after wiping, and the skin compatibility is poor.
  • the anti-mosquito function is prepared into an emulsion suitable for human skin, which can solve the problems of mosquito repellent being volatile, requiring multiple application and poor skin adaptability.
  • Still another object of the present invention is to provide an anti-mosquito emulsion which is encapsulated in an anti-mosquito component by using an essential oil compatible with the skin to form an adsorption layer which is compatible with the skin, so that the prepared anti-mosquito emulsion More suitable for skin surface use.
  • an anti-mosquito emulsion comprising the following ingredients (by mass fraction):
  • Ingredient A linalool: citronellol: geraniol is 1:1:1 to 1:2:2;
  • Ingredient B Ai Ye essential oil
  • Component C lecithin, 2 to 5 parts; ephedrine, 0.001 to 0.1 parts; alfalfa extract, 0.5 to 1 part; natural squalane, 2 to 10 parts; VE or VE derivative, 1 to 5 parts;
  • Ingredient D glycerin, 8 to 18 parts; the balance is water;
  • component A and component B are uniformly mixed in a ratio of 1:4 to 2:3; component C and component D are uniformly mixed, and a mixture of component A and component B is added, and then emulsifier is added in an amount of 6 to 12 parts, and surfactant is 0.2. ⁇ 0.5 parts, a consistency adjuster of 3.8 to 10 parts; a mixture of component A and component B: a mixture of component C and component D is 1:5 to 2:5.
  • the anti-mosquito emulsion comprises the following components (by mass fraction):
  • Ephedrine 0.1 part
  • Emulsifier 6 parts
  • Consistency adjuster 3.8 parts
  • the balance is water.
  • the anti-mosquito emulsion comprises the following components (by mass fraction):
  • Linalool 0.7 parts
  • Citronellol 1.4 parts
  • Ephedrine 0.001 parts
  • Emulsifier 12 parts
  • the balance is water.
  • the anti-mosquito emulsion comprises the following components (by mass fraction):
  • Ephedrine 0.05 parts
  • Emulsifier 9 parts
  • Consistency adjuster 6.6 parts
  • the balance is water.
  • the mosquito repellent emulsion wherein the VE derivative is VE acetate.
  • the anti-mosquito emulsion wherein the mixing of the component A and the component B is specifically: using distilled water to distill the leaves of the leaves to form steam, and continuously continuing to transfer the high-temperature steam to a certain amount within 8 to 10 days.
  • a container of linalool, citronellol and geraniol a mixture of linalool, citronellol and geraniol mixed with steam is mixed to form the component A, and the component A is mixed with the component B. Evenly.
  • the anti-mosquito emulsion wherein the mixing of the component C and the component D is specifically: taking a certain amount of VE or VE derivative, soaking it in a small amount of glycerin for 2 to 5 days, Adding ephedrine; adding a certain amount of lecithin, medlar extract and natural squalane to glycerin, soaking for 2 to 5 days, shaking 3 to 6 times a day for 5 to 10 minutes; adding ephedrine
  • the glycerin mixture containing VE or VE derivative is rapidly added to a mixture of glycerol containing lecithin, medlar extract and natural squalane, and an appropriate amount of water is added thereto, and shaken for 10 to 30 minutes at a temperature of 20 to 40 ° C to obtain the above-mentioned a mixture of component C and component D.
  • the mosquito-repellent emulsion wherein the mixture of the component A and the component B obtained and the mixture of the component C and the component D are remixed at a pressure of 0.5 to 1.33 After heating to 100-120 ° C under kPa for 3 to 10 minutes, the temperature is lowered to 60-70 ° C, and the mixture is filtered to remove slag, and then subjected to high-pressure steam sterilization to obtain an emulsion for controlling mosquito bites.
  • the anti-mosquito emulsion further comprises saffron.
  • the anti-mosquito emulsion wherein 0.2 to 1 g of the saffron is soaked in 200-600 mL of water, soaked for 20 to 40 minutes, heated and boiled to the remaining 60-200 mL of water, and the upper layer of mash is taken. It is added to the mixture of the component A and the component B at a mass ratio of 1:5 to 1:8.
  • linalool, citronellol and geraniol as main functional components for mosquito control, distilling water to distillate water to form steam, using steam to fume linalool, citronellol and geraniol to make linden Alcohol, citronellol and geraniol are combined with the active ingredients of the leaves, so that they are suitable for direct contact with human skin;
  • the linalool, citronellol and geraniol, which have been steamed by Aiye steam, are mixed in a certain proportion, which can not only achieve mosquito repellent and mosquito repellent effect, but also suitable for long-term contact with body surface skin;
  • Ai Ye essential oil mixed with linalool, citronellol and geraniol Ai Ye essential oil coated with linalool, citronellol and geraniol molecules to form a functional molecule suitable for contact with the skin;
  • lecithin, medlar extract and natural squalane can not only enhance the skin's self-defense ability, but also enhance the skin's adaptability to the mixed ingredients of eucalyptus essential oil, linalool, citronellol and geraniol, enhance functional ingredients in Adsorption of the skin surface, so that the emulsion has a long-lasting mosquito repellent effect;
  • the VE or VE derivative added with ephedrine is an active ingredient which activates the activity of the mixture of component C and component D for the mixture of component A and component B, maintains its long-lasting functionality, delays its release, and enhances the durability of the emulsion. And adsorption on the surface of the skin;
  • the quantitative saffron supernatant is added to the mixture of the component A and the component B, so that the saffron is adsorbed on the surface of the essential oil molecules to improve the comfort of the skin after the emulsion is applied.
  • the present invention provides an anti-mosquito emulsion comprising the following components (by mass fraction):
  • Ingredient A linalool: citronellol: geraniol is 1:1:1 to 1:2:2;
  • Ingredient B Ai Ye essential oil
  • Component C lecithin, 2 to 5 parts; ephedrine, 0.001 to 0.1 parts; alfalfa extract, 0.5 to 1 part; natural squalane, 2 to 10 parts; VE or VE derivative, 1 to 5 parts;
  • Ingredient D glycerin, 8 to 18 parts; the balance is water;
  • component A and component B are uniformly mixed in a ratio of 1:4 to 2:3; component C and component D are uniformly mixed, and a mixture of component A and component B is added, and then emulsifier is added in an amount of 6 to 12 parts, and surfactant is 0.2. ⁇ 0.5 parts, a consistency adjuster of 3.8 to 10 parts; a mixture of component A and component B: a mixture of component C and component D is 1:5 to 2:5.
  • VE derivative is VE acetate.
  • the mixing of the component A and the component B is specifically: using distilled water to distill the leaves of the leaves to form steam, and continuously continuing to transfer the high-temperature steam into a container containing a certain amount of linalool, citronellol and geraniol within 8 to 10 days. Inside, the linalool, citronellol, and geraniol mixed with steam are mixed to form the component A, and the component A and the component B are uniformly mixed.
  • the mixing of the component C and the component D is specifically: taking a certain amount of VE or VE derivative, soaking it in a small amount of glycerin for 2 to 5 days, adding ephedrine thereto; and adding a certain amount of lecithin and strontium
  • the extract and natural squalane are sequentially added to glycerin, soaked for 2 to 5 days, shaken 3 to 6 times a day for 5 to 10 minutes each time; the glycerin mixture containing VE or VE derivative added to ephedrine is quickly added to A mixture of glycerol containing lecithin, medlar extract and natural squalane is added with an appropriate amount of water, shaken for 10 to 30 minutes, and the temperature is 20 to 40 ° C to obtain a mixture of the component C and the component D.
  • Ephedrine 0.1 part
  • Emulsifier 6 parts
  • Consistency adjuster 3.8 parts
  • the balance is water.
  • VE derivative is VE acetate.
  • the mixing of the component A and the component B is specifically: distilling steam to form a steam by using distilled water, and continuously transferring the high-temperature steam into a container containing a certain amount of linalool, citronellol and geraniol within 9 days.
  • the linalool, citronellol, and geraniol mixed with steam are mixed to form the component A, and the component A and the component B are uniformly mixed.
  • the mixing of the component C and the component D is specifically: taking a certain amount of VE or VE derivative, immersing it in a small amount of glycerin for 4 days, adding ephedrine thereto; and adding a certain amount of lecithin and strontium extract And natural squalane is added to the glycerin in turn, soaked for 4 days, shaken 5 times a day for 7 minutes each time; the glycerin mixture containing VE or VE derivative added with ephedrine is quickly added to the lecithin-containing, sputum extract and To the glycerin mixture of natural squalane, an appropriate amount of water was added, and the mixture was shaken for 20 minutes at a temperature of 30 ° C to obtain a mixture of the component C and the component D.
  • Linalool 0.7 parts
  • Citronellol 1.4 parts
  • Ephedrine 0.001 parts
  • Emulsifier 12 parts
  • the balance is water
  • VE derivative is VE acetate.
  • the mixing of the component A and the component B is specifically: distilling steam to form a steam using distilled water, and continuously transferring the high-temperature steam into a container containing a certain amount of linalool, citronellol and geraniol within 8 days.
  • the linalool, citronellol, and geraniol mixed with steam are mixed to form the component A, and the component A and the component B are uniformly mixed.
  • the mixing of the component C and the component D is specifically: taking a certain amount of VE or VE derivative, immersing it in a small amount of glycerin for 2 days, adding ephedrine thereto; and adding a certain amount of lecithin and strontium extract And natural squalane is sequentially added to glycerin, soaked for 2 days, shaken 3 times a day for 5 minutes each time; the glycerin mixture containing VE or VE derivative added with ephedrine is quickly added to the lecithin-containing, sputum extract and To the glycerin mixture of natural squalane, an appropriate amount of water was added, and the mixture was shaken for 10 minutes at a temperature of 20 ° C to obtain a mixture of the component C and the component D.
  • Ephedrine 0.05 parts
  • Emulsifier 9 parts
  • Consistency adjuster 6.6 parts
  • the balance is water
  • VE derivative is VE acetate.
  • the mixing of the component A and the component B is specifically: distilling water into a steam using distilled water, and continuously transferring the high-temperature steam into a container containing a certain amount of linalool, citronellol and geraniol within 10 days.
  • the linalool, citronellol, and geraniol mixed with steam are mixed to form the component A, and the component A and the component B are uniformly mixed.
  • the mixing of the component C and the component D is specifically: taking a certain amount of VE or VE derivative, immersing it in a small amount of glycerin for 5 days, adding ephedrine thereto; and adding a certain amount of lecithin and strontium extract And natural squalane is sequentially added to glycerin, soaked for 5 days, shaken 6 times a day for 10 minutes each time; the glycerin mixture containing VE or VE derivative added with ephedrine is quickly added to the lecithin-containing extract and the extract To the glycerin mixture of natural squalane, an appropriate amount of water was added, and the mixture was shaken for 30 minutes at a temperature of 40 ° C to obtain a mixture of the component C and the component D.
  • Ephedrine 0.1 part
  • Emulsifier 6 parts
  • Consistency adjuster 3.8 parts
  • the balance is water.
  • VE derivative is VE acetate.
  • the mixing of the component A and the component B is specifically: distilling steam to form a steam by using distilled water, and continuously transferring the high-temperature steam into a container containing a certain amount of linalool, citronellol and geraniol within 9 days.
  • the linalool, citronellol, and geraniol mixed with steam are mixed to form the component A, and the component A and the component B are uniformly mixed.
  • 0.2 g of the saffron was soaked in 200 mL of water, soaked for 20 minutes, heated and boiled to the remaining 60 mL of water, and the upper layer of the mash was added to the mixture of the component A and the component B at a mass ratio of 1:5.
  • the mixing of the component C and the component D is specifically: taking a certain amount of VE or VE derivative, immersing it in a small amount of glycerin for 4 days, adding ephedrine thereto; and adding a certain amount of lecithin and strontium extract And natural squalane is added to the glycerin in turn, soaked for 4 days, shaken 5 times a day for 7 minutes each time; the glycerin mixture containing VE or VE derivative added with ephedrine is quickly added to the lecithin-containing, sputum extract and To the glycerin mixture of natural squalane, an appropriate amount of water was added, and the mixture was shaken for 20 minutes at a temperature of 30 ° C to obtain a mixture of the component C and the component D.
  • the prepared mixture of the component A containing the saffron and the component B is remixed with the mixture of the component C and the component D, and heated to 110 ° C under a pressure of 1.1 kPa for 8 minutes. After that, the temperature is lowered to 65 ° C, and the mixture is filtered to remove slag, and then subjected to autoclaving, thereby obtaining an emulsion for controlling mosquito bites.
  • Ephedrine 0.05 parts
  • Emulsifier 9 parts
  • Consistency adjuster 6.6 parts
  • the balance is water
  • VE derivative is VE acetate.
  • the mixing of the component A and the component B is specifically: distilling water into a steam using distilled water, and continuously transferring the high-temperature steam into a container containing a certain amount of linalool, citronellol and geraniol within 10 days.
  • the linalool, citronellol, and geraniol mixed with steam are mixed to form the component A, and the component A and the component B are uniformly mixed.
  • the mixing of the component C and the component D is specifically: taking a certain amount of VE or VE derivative, immersing it in a small amount of glycerin for 5 days, adding ephedrine thereto; and adding a certain amount of lecithin and strontium extract And natural squalane is sequentially added to glycerin, soaked for 5 days, shaken 6 times a day for 10 minutes each time; the glycerin mixture containing VE or VE derivative added with ephedrine is quickly added to the lecithin-containing extract and the extract To the glycerin mixture of natural squalane, an appropriate amount of water was added, and the mixture was shaken for 30 minutes at a temperature of 40 ° C to obtain a mixture of the component C and the component D.
  • Example 2 Comparing the emulsions prepared in Example 1, Example 2 and Example 3 with the anti-mosquito water commercially available for human body surface, the skin comfort of the products of Examples 1, 2 and 3 was significantly better than the existing mosquito prevention. Water and found implementation Emulsion durability in Example 1>Example 3>Example 2.
  • Example 4 The emulsions prepared in Example 1, Example 4 and Example 5 were rubbed on the body surface, and it was found that the emulsion comfort of Example 4 and Example 5 was better than that of Example 1.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Epidemiology (AREA)
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Abstract

Cette émulsion antimoustique comprend la composition suivante, exprimée en fraction massique avec comme ingrédients du groupe A linalol : citronellol : geraniol selon un rapport de 1 : 1 : 1 - 1 : 2 : 2; avec comme ingrédient du groupe B P-cymène; avec comme ingrédients du groupe C 2 à 5 parties de lécithine, 0,001 à 0,1 partie d'éphédrine, 0,5 à 1 partie d'un extrait de Wolfiporia extensa, 2 à 10 parties de squalane naturel, 1 à 5 parties de VE ou de dérivés de VE; avec comme ingrédient du groupe D 8 à 18 parties de glycérol, le reste étant de l'eau, le rapport du mélange uniforme entre les ingrédients des groupes A et B étant de 1 : 4 à 2 : 3. Après mélange des ingrédients des groupes C et D, on ajoute le mélange des ingrédients des groupes A et B auquel on ajoute 6 à 12 parties d'une émulsion, 0,2 à 0,5 partie d'un agent tensio-actif, 3,8 à 10 parties d'un régulateur de consistance. Le rapport du mélange obtenu entre les ingrédients des groupes A et B et les ingrédients des groupes C et D est de 1 : 5 à 2 : 5. Les huiles essentielles utilisées faisant preuve d'une compatibilité satisfaisante enrobent les ingrédients antimoustique afin de former une couche de respiration compatible avec la peau de telle sorte que l'émulsion antimoustique se prête à une utilisation sur la surface de la peau.
PCT/CN2017/086766 2016-06-22 2017-06-01 Émulsion antimoustique WO2017219838A1 (fr)

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Application Number Priority Date Filing Date Title
CN201610452777.0 2016-06-22
CN201610452777.0A CN105997660A (zh) 2016-06-22 2016-06-22 防蚊乳液

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WO2017219838A1 true WO2017219838A1 (fr) 2017-12-28

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Cited By (2)

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