WO2017209572A1 - Dispositif d'échantillonnage de tissu biologique - Google Patents

Dispositif d'échantillonnage de tissu biologique Download PDF

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Publication number
WO2017209572A1
WO2017209572A1 PCT/KR2017/005813 KR2017005813W WO2017209572A1 WO 2017209572 A1 WO2017209572 A1 WO 2017209572A1 KR 2017005813 W KR2017005813 W KR 2017005813W WO 2017209572 A1 WO2017209572 A1 WO 2017209572A1
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WO
WIPO (PCT)
Prior art keywords
case
holder
biopsy
space
inner space
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Application number
PCT/KR2017/005813
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English (en)
Korean (ko)
Inventor
이동석
류대식
Original Assignee
주식회사 메디아나
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by 주식회사 메디아나 filed Critical 주식회사 메디아나
Publication of WO2017209572A1 publication Critical patent/WO2017209572A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B2010/0208—Biopsy devices with actuators, e.g. with triggered spring mechanisms

Definitions

  • the present invention when the needle exposed from the case is penetrated into the biological part to be collected and the firing button is operated, the inner needle of the needle is momentarily advanced to the biological tissue to be collected to receive a part of the biological tissue in the receiving space, and time difference
  • the present invention relates to a biological tissue specimen device for sequentially collecting an outer needle along a inner needle to a biological tissue to be collected and cutting the biological tissue contained in the inner needle while closing the receiving space of the inner needle to collect the biological tissue.
  • tissue biopsy is a test for identifying the tissue pathology of the organs of the human body (kidney, lung, liver, kidney, spleen, pancreas, etc.).
  • the tissue biopsy is obtained in the most obvious way to determine the pathologic state of the organs in the human body is subjected to a histological examination through a microscope.
  • the tissue biopsy may be performed using an ultrasound guided fine needle biopsy under ultrasound or radiation instrument guidance, whereby an assisting practitioner may hold and assist with an ultrasound probe, or the operator may hold an ultrasound probe with one hand and with the other hand.
  • the procedure is performed by holding a syringe or biopsy specimen.
  • the invention is to extract the biological tissue by pushing the piston inside the cylinder forward or pulled backward for the biopsy and treatment of the living body with an aspiration Biopsy apparatus.
  • Republic of Korea Patent Publication No. 10-1998-0701687 is an invention to form a spring therein to collect the tissue by the elasticity of the spring, when a number of tests are carried out, there is a feature that the fatigue of the hand is accumulated and the stability is lowered.
  • the conventional total biopsy sampler is large in size, and when collecting the tissue for cell examination, the hand holding the ultrasonic probe is released and the biopsy tissue sampler is operated with both hands, or one hand each. The ultrasonic probe must be held in place and the biopsy specimen can be operated with the other hand.
  • the present invention is easy to hold in the hand, smaller cross-sectional area than the conventional small lung cancer can be aimed vertically, the dependence of the assistant is reduced, by selectively retracting only the outer needle, disassemble the device, or collected through the needle without damage It is an object of the present invention to provide a biological tissue sample device that is easy to collect tissue.
  • the biological tissue sample device has a space formed therein, and is provided with a case having a bar shape and being movable along an inner space of the case, and selectively operated by a user.
  • a biopsy receiving portion for advancing along the space and accommodating the biological tissue, and is provided to be movable along the inner space of the case, and after the biopsy receiving portion advances to advance along the inner space of the case in order to cut the biological tissue
  • a biopsy cutting unit and a loading block connected to the biopsy receiving unit and the biopsy cutting unit with a plurality of connecting shafts in the inner space of the case, to pull the biopsy receiving unit and the biopsy cutting unit to the rear during the retreat movement, and the rear of the case Is coupled to the outside, connected to the loading block moving along the inner space, the loading block to move backward Includes a loading lever.
  • the biopsy receiving portion is disposed in the inner needle and the inner space of the case is formed in the accommodating space for accommodating the biopsy in the front end, the rear end of the inner needle is coupled to the front surface, the first side A first holder having a locking jaw, a first coil spring disposed behind the first holder in the inner space of the case, and disposed above the inner space of the case, And a first hook member for supporting a first catching jaw of the first holder retracting along the inner space of the case to maintain the compressed state of the first coil spring carrying the first holder.
  • the biopsy cutting portion is a tubular having a hollow, advancing along the inner needle while receiving the inner needle through the hollow to close the receiving space while cutting the biopsy located in the receiving space of the inner needle
  • a second holder disposed in an outer needle and an inner space of the case, the rear end of the outer needle being coupled to a front surface, and having a second catching jaw on the front upper side; and the second holder in the inner space of the case.
  • a second coil spring disposed behind the second holder and holding the second holder on the front side of the case in which the second holder is disposed, and retreating along the inner space of the case; And a second hook member for supporting a second catching jaw of the second hook spring so as to maintain a compressed state of the second coil spring holding the second holder.
  • the firing button according to the present invention is disposed on the outside of the case, the pressing plate, the user's finger is placed, the shaft extending downward from the bottom of the pressing plate, and the fixed plate formed of a diameter larger than the diameter of the shaft at the bottom of the shaft And a launch preventing jaw extending in one radial direction from the bottom of the pressing plate, and a click protrusion formed at a lower portion of the fixing plate to form a vertical line with the launch preventing jaw.
  • the connecting shaft according to the present invention is spaced apart from each other, and a pair of first connecting shafts connecting the front surface of the first holder and the rear surface of the second holder through the second coil spring and spaced apart from each other. And a pair of second connecting shafts connecting the rear surface of the first holder and the front surface of the loading block through the first coil spring.
  • the biological tissue sample device forms a release piece for operating the second hook member on the front end of one of the pair of first connecting shafts.
  • the loading lever according to the present invention is coupled to the hinge shaft formed on the rear side of the case, and the handle piece is folded and rotated by the hinge axis to the shaft, respectively formed extending from the left and right of the handle piece, A coupling piece for interviewing the rear left and right sides, and a coupling hole formed in the coupling piece, the hinge hole is coupled to the hinge axis of the case and the loading hole is connected to the loading block.
  • an open lever for retracting the biopsy cutting portion while selectively sliding back to move by the user operation, to open the biopsy receiving portion.
  • the open lever according to the present invention is formed so as to be coupled to the lower portion of the front side of the case, the body forming a 'U' cross-section, extending upward from the inside of the body, to interview the front side of the second holder Include recession.
  • the biological tissue sample device according to the embodiment of the present invention has the following effects.
  • the overall cross-sectional width of the specimen device is easier to grip in the hand, as the smaller than the conventional small lung cancer can be aimed vertically, it has the effect of increasing the accuracy of the specimen.
  • the front of the case is provided with an open lever for selectively retracting only the outer needle, there is an effect that the collection of biological tissue collected through the needle without disassembling or damaging the device.
  • FIG. 1 is an exploded perspective view showing the decomposition of the components of the biological tissue sample device according to an embodiment of the present invention.
  • Figure 2 is a cross-sectional view showing a cross-sectional view of the biological tissue sample device according to an embodiment of the present invention.
  • Figure 3 is an exemplary view showing a cross-sectional view of the operating state of the loading lever of the biological tissue specimen device according to an embodiment of the present invention.
  • FIG. 4 is an exemplary view showing a state in which the inner needle of the biological tissue sample device according to an embodiment of the present invention is advanced in cross section.
  • FIG 5 is an exemplary view showing a state in which the outer needle of the biological tissue sample device according to an embodiment of the present invention is advanced in cross section.
  • Figure 6 is an exemplary view showing a cross-sectional view of operating the open lever of the biological tissue specimen device according to an embodiment of the present invention.
  • Figure 7 is an exemplary view showing another embodiment of the inner needle in accordance with the present invention.
  • Figure 8 is an exemplary view showing another embodiment of the inner needle in accordance with the present invention.
  • the present invention has a case forming a bar-shaped body having a length in the front and rear directions, and an inner needle having an accommodating space for accommodating a biopsy at the front end, and is supported by the first coil spring in the inner space of the case.
  • a first holder and an outer needle which closes the accommodation space while cutting the biopsy positioned in the accommodation space with the front end portion while moving along the inner needle while accommodating the inner needle, and the second coil in the inner space of the case.
  • a second holder supported by a spring and disposed in front of the first holder, a loading block connected to a plurality of connecting shafts in the inner space of the case, towing the first holder and the second holder, and a rear of the case; Is coupled to the hinge shaft formed on the side, connected to the loading block moving along the inner space of the case, by rotating the hinge axis to the axis to follow the loading block space Retraction of the loading lever, and with a sliding movement rearward from a front of the case by retracting the second holder, there is provided a biological tissue sample device comprising an opening lever for opening the accommodation space of the first needle.
  • the present invention when the needle exposed from the case penetrates the biological part to be collected and operates the firing button, the inner needle of the needle is momentarily advanced to the biological tissue to be collected to receive a part of the biological tissue in the receiving space,
  • the present invention relates to a biological tissue specimen device for collecting biological tissue by closing the receiving space of the inner needle while cutting the biological tissue accommodated in the inner needle by sequentially moving the outer needle along the inner needle to the biological tissue to be collected.
  • the biological tissue sample device forms a bar-shaped body having a length in the front, rear direction, and the case 100 to form a space in the longitudinal direction therein and
  • the biopsy receiving unit (unsigned) is provided to move along the inner space of the case 100 and selectively moves along the inner space of the case 100 by a user's operation to receive the biological tissue.
  • a biopsy cutting part (not shown) is provided to move along an inner space of the case 100 and sequentially moves along the inner space of the case 100 as the biopsy receiving portion (unsigned) moves forward. It includes.
  • the case 100 will be described in more detail. As shown in FIGS. 1 and 2, the case 100 is cut in the longitudinal direction before and after, and is detachable to the left and right sides, and the case 100.
  • the front end of the through-hole 101 is formed to penetrate, the rear of the hinge shaft 102 to the left and right outwards to form a protrusion.
  • the through-hole 101 through which the needle penetrates is formed in the case 100, and the closing cap 110 made of a metal material is screwed to the protrusion, and the needle is closed while closing the front end of the case 100. Guide to secure the straightness of the needle.
  • a guide long hole 103 is formed in the longitudinal direction at the rear of the case 100 in which the hinge shaft 102 is formed, and a coupling hole 500 is coupled to the upper surface of the middle part of the case 100. 104 is formed.
  • the inside of the case 100 is formed with a cylindrical space in the longitudinal direction before, after, a pair of diaphragm member 120 is provided in the space of the case 100, a cylindrical space It is divided into three spaces.
  • the pair of diaphragm member 120 that partitions the space is preferably formed in a ring-shaped perforated center, a pair of fixing grooves 105 formed spaced apart on the inner circumferential surface of the case 100 The diaphragm member 120 is fixed to each.
  • the diaphragm member 120 is seated and fixed to the pair of fixing grooves 105 formed on the inner circumferential surface of the case 100 so as to partition the space of the case 100 into three spaces.
  • the first holder 210, the biopsy cutting second holder 220, and the loading block 230 are respectively disposed in the three spaces partitioned by the diaphragm members 120, respectively.
  • the holder 210 is disposed in the center space among the three spaces partitioned inside the case 100, and the second holder 210 is disposed in the front side space with respect to the center space, and is rearward with respect to the center space.
  • the loading block 230 is disposed in the side space, and the second holder 220 of the biopsy cutting part, the first holder 210 of the biopsy receiving part, and the loading block 230 are arranged in series in the space of the case 100. do.
  • the biopsy receiving portion includes an inner needle 10, the first holder 210, the first coil spring 310, the first hook member 410, Figures 2 to 5
  • the first holder 210 disposed in the center space forms a cylindrical body so as to correspond to the space, and is supported by the first coil spring 310 to move forward of the space by the elastic repulsive force.
  • the first holder 210 moves backward along the space, the first holder in the first hook member 410 provided in the case 100 in the compressed state of the first coil spring 310 210 is caught to maintain the first coil spring 310 in a compressed state.
  • the first catching jaw 211 corresponding to the first hook member 410 is formed to protrude from the upper side of the first holder 210, and the inner needle at the front end of the first holder 210.
  • the rear end of the 10 is connected, the inner needle 10 is formed in the front receiving space 11 for receiving a biopsy. The biopsy is taken through the receiving space 11 by advancing forward by the first holder 210 advancing by the elastic repulsive force of the first coil spring 310.
  • the receiving space 11 of the inner needle 10 is formed in a plurality as shown in Figure 2 to increase the acquisition rate of the biopsy, wherein the plurality of receiving space 11 is the outer periphery of the inner needle Is preferably formed accordingly.
  • the first hook member 410 is operated to release the first holder 210, the first holder 210 moves forward by the elastic repulsive force of the first coil spring 310.
  • the needle 10 also moves forward and the inner needle 10 collects a biopsy through the receiving space 11.
  • the first hook member 410 is spaced in the case 100 so that the first hook member 410 may correspond to the first catching jaw 211 formed on the upper side of the first holder 210 in the case 100. It is coupled to the first fixed shaft 106 formed on the upper side.
  • the first hook member 410 has one side 411 having a hook corresponding to the first catching jaw 211 of the first holder 210 and the other side 412 in contact with the firing button 500. It includes, one side 411 and the other side 412 of the first hook member 410 to seesaw the first fixed shaft 106 to the axis, the other side 412 of the first hook member 410 ) Is located at the coupling hole 104 side of the case 100 to correspond to the firing button 500.
  • first hook member 410 is coupled to the first fixed shaft 106 in a state of being held by a torsion spring (not shown), the elasticity of the torsion spring of the first holder 210
  • One side 411 of the first hook member 410 on which the first catching jaw 211 is held is inclined to be positioned below the other side 412 of the first hook member 410.
  • the first hooking jaw 211 of the first holder 210 retracted along the space of the case 100 is caught by one side 411 of the first hook member 410 in the above state.
  • the other side 412 of the first hook member 410 is also located above one side 411 of the first hook member 410 and tortures the launch button 500 while contacting the bottom of the launch button 500. Supported by the elastic force of the spring, the firing button 500 is provided in the coupling hole 104 of the case 100, the other side of the first hook member 410 in contact with the operation of the selective user ( 412 is pushed downward to raise one side 411 of the first hook member 410 to release the first holder 210.
  • the firing button 500 is located on the outside of the case 100, and includes a pressing plate 510, the user's finger is placed, the shaft formed extending downward from the bottom of the pressing plate 510 ( And a fixing plate 530 formed at a diameter larger than the diameter of the shaft 520 at the lower end of the shaft 520.
  • the shaft 520 of the firing button 500 is preferably disposed in the coupling hole 104 of the case 100, and the pressing plate 510 located above the shaft 520 is the case (
  • the fixing plate 530 which is exposed to the outside of the 100 and positioned below the shaft 520 is positioned inside the case 100, so that the firing button 500 is coupled to the case 100. It is possible to move up and down along the 104, and the firing button 500 is coupled by the fixing plate 530 having a diameter larger than the shaft 520 without falling out of the coupling hole 104 of the case 100 Maintain state.
  • the bottom of the pressing plate 510 is formed to extend the launch prevention jaw 511 in any one radial direction, the launch prevention jaw 511 is located between the pressing plate 510 and the case 100, the pressing plate ( The lowering of the 510 is interrupted to interrupt the operation of the first hook member 410.
  • the coupling hole 104 of the case 100 extends a communication hole corresponding to the anti-shooting jaw 511 so that the anti-firing jaw 511 is selectively communicated with the coupling hole 104 by a user's manipulation. If the ball is located corresponding to the pressing plate 510 to be lowered.
  • the user may change the position of the launch prevention jaw 530 by rotating the pressing plate 510 of the launch button 500, and as the position of the launch prevention jaw 511 is changed, A lock that lifts and lowers the lift and an unlock that allows the lift of the firing button 500 may be selected.
  • a click protrusion 531 is formed on the bottom of the fixing plate 530 of the firing button 500 on the same vertical line as the anti-shooting jaw 511, and the click protrusion is formed on the other side of the first hook member 410.
  • Forming a groove (unsigned) to which the 531 is seated, and when the user selects an unlock (unlock) to allow the lift button 500 to move up by rotating the pressing plate 510, the launch prevention jaw 511 is selected.
  • the click protrusion 531 positioned on the vertical line as shown in FIG. 2 may be felt by a finger, which is seated in a seating groove (unsigned) formed on an upper surface of the other side 412 of the first hook member 410.
  • the lifting and lowering of the firing button 500 to the click projection 531 is intermittent. It can also be formed in a position where the lock (lock) to be known.
  • the biopsy cutting unit includes an outer needle 20, the second holder 220, the second coil spring 320, the second hook member 420, Figures 2 and 3
  • the second holder 220 of the biopsy cutting part located in front of the first holder 210 also forms a cylindrical body so as to correspond to the space, and is supported by the second coil spring 320 to be elastically repulsive.
  • 1 holder 210 is moved forward with a time difference.
  • the second coil spring 320 is compressed and the second holder 220 is provided on the second hook member 420 provided inside the case 100.
  • the second coil spring 320 is compressed.
  • a second catching jaw 221 corresponding to the second hook member 420 is formed to protrude from the upper side of the second holder 220.
  • the front end of the second holder 220 is connected to the rear end of the outer needle 20, the outer needle 20 is formed in the form of a tube having a hollow along the longitudinal direction so that the inner needle 10 is received therein
  • the biopsy positioned in the accommodation space 11 is moved forward along the inner needle 10 to be formed at the front end.
  • the receiving space 11 is closed while cutting with the cutter blade.
  • the second holder 220 is provided in the front space on the basis of the space in which the first holder 210 is disposed among the partitioned spaces of the case 100 while being held by the second coil spring 320.
  • the second coil spring 320 is moved to the rear of the space so as to be compressed, the second hooking jaw 221 of the second holder 220 is caught by the second hook member 420, and the second coil is caught.
  • the second holder 220 is intermittently moved forward.
  • the first hook member 410 and the second hook member 420 are sequentially operated to release the hook of the second hook member 420, the second holder 220 is connected to the second coil spring.
  • the outer needle 20 advances forward along the inner needle 10 to close the receiving space 11 while cutting the biopsy positioned in the receiving space 11 as it moves forward by the elastic repulsive force of 320. .
  • the first holder 210 and the second holder 220 are connected to each other by a pair of first connecting shafts 240, wherein the pair of first connecting shafts 240 are each up and down on a vertical line. Spaced apart from each other, a rear end of the pair of first connecting shafts 240 is connected to the first holder 210, and a front end of the pair of first connecting shafts 240 is inside the second coil spring 320. It is connected to the second holder 220 through.
  • the rear ends of the first connecting shafts 240 are provided with a flange protruding radially outward from the rear of the first holder 210 after passing through the inside of the first holder 210,
  • the front end of the first connecting shafts 240 has a flange that passes through the inside of the second holder 220 and protrudes in a radial direction so that the front end does not fall out, so that the second holder 220 is connected to the first connection. It slides along the shaft 240. At this time, when the first connecting shaft 240 is retracted to the first holder 210, the second holder 220 is pulled back by the front end of the first connecting shaft 240 by the flange.
  • the second coil spring 320 when the outward side surfaces of the spaced first coupling shaft 240 contact the inner circumferential surface of the second coil spring 320 to compress and relax the second coil spring 320. Guided to operate in a straight line, the inner needle 10 is advanced evenly in a straight line.
  • the inner needle 10 fixed to the front of the first holder 210 is located between the pair of first connection shafts 240 fixed to be spaced apart from the center of the second holder 220 to the case It leads to the outside through the through hole 101 of (100).
  • a release release piece 241 is formed at a front end of the first connection shaft 240 positioned above the pair of first connection shafts 240, and the release piece 241 is formed in the second holder.
  • the second hook member 420 for controlling the advancement of the 220 is operated to release the engagement of the second holder 220.
  • the upper surface of the second holder 220 forms a guide groove 222 into which the unlocking piece 241 can enter in the longitudinal direction.
  • the first hook member 410 is operated to release the first holder 210 from the first holder 210.
  • the first connecting shaft 240 fixedly coupled to the first holder 210 is advanced.
  • the inner needle 10 coupled to the first holder 210 is advanced to collect tissue.
  • the release piece 241 formed at the front end of the first connecting shaft 240 also moves along the guide groove 222 of the second holder 220 while moving the second hook member 420.
  • the second holder 220 is released at a time difference from the first holder 210 to allow the second holder 220 to move forward into the space so that the outer needle 20 has an inner needle ( Operate according to 10).
  • the inner needle 10 is advanced to the biological site to take the biopsy, and then the outer needle with the advance of the second holder 220 with a time difference While the 20 advances along the inner needle 10 to the site where the biopsy is to be taken, the biopsy is cut and the biopsy is received in the inner needle to collect the biopsy.
  • the loading block 230 is disposed in the rear side space of the case 100 based on the center space in which the first holder 210 is disposed among the three spaces formed in the case 100, and thus, the first holder. It is arrange
  • a pair of loading protrusions 231 protrude outwards on the left and right sides of the loading block 230, respectively, the pair of loading protrusions 231 is the case 100 Coupled to the guide hole 103 of the, the loading block 230 is moved along the guide hole 103 by a pair of loading projections (231).
  • the pair of loading protrusions 231 coupled to the guide long hole 103 is also coupled to the loading long hole 601 of the loading lever 600 coupled to the rear of the case 100, the loading lever 600 ),
  • the loading block 230 is retracted by moving backward along the guide slot 103 of the case 100 by receiving a force backward by the loading slot 601 of the loading lever 600.
  • the loading lever 600 rotates the hinge shaft 102 to the axis by the user's operation at the lower portion of the case 100, so that the loading lever 600 can be flipped backward.
  • the engaging piece in contact with the rear left and right sides of the case 100 is extended to the left and right, and combined as if the rear of the case 100, the coupling piece
  • the hinge hole 601 is formed to be coupled to the hinge shaft 102 of the case 100, and the loading hole 602 is formed below the hinge hole 601.
  • the loading block 230 is connected to the first holder 210 by a second connecting shaft 250.
  • the loading lever 600 When the loading lever 600 is rotated by a user, the loading block 230 is When the first holder 210 is retracted by pulling the first holder 210 through the second connecting shaft 250 while retreating by the loading lever 600, and the first holder 210 is retracted,
  • the second holder 220 connected to the first connecting shaft 240 also retreats to engage the first holder 210 and the second holder 220.
  • a rear end of the pair of second connecting shafts 250 is fixedly spaced apart from each other on the loading block 230 at an interval, and a front end of the second connecting shaft 250 is the first coil spring 310. Through the inside and fixed to the rear of the first holder 210.
  • the first holder 210 and the loading block 230 are integrally formed by the pair of second connection shafts 250, so that the loading block 230 is the loading lever 600.
  • the first holder 210 is released and the elasticity of the first coil spring 310
  • the loading block 230 also advances by the traction of the second connecting shaft 250.
  • the pair of second connection shafts 250 are provided so that the outward side of each other abuts the inner circumferential surface of the first coil spring 310, when the compression and relaxation of the first coil spring 310, The first coil spring 310 is guided to operate in a straight line.
  • the front of the case 100 is provided with an open lever 700 as shown in Figs. 1 and 5, the open lever 700 is preferably provided in the front lower portion of the case 100, And, so as to surround the front lower portion of the case 100, having a body having a cross-section 'U' shape, the inside of the body is received in the front of the case 100 while the second holder 220 Protruding form the retreat piece 701 to be interviewed with the front surface.
  • the outer needle 20 also retreats backward along the inner needle 10 to accommodate the space of the inner needle 10 ( 11) is opened, it is possible to easily learn the biological tissue accommodated in the receiving space (11).
  • the arrangement of the receiving space formed at the front end of the inner needle 10 is not limited to that shown in Figure 2, it can be adapted according to the range and position of the biopsy, for example as shown in Figure 7 Dog receiving spaces 11 are arranged in a zigzag along the longitudinal direction of the inner needle 10, or as shown in Figure 8 a plurality of receiving spaces 11 to any one side of the inner needle (10) It may be formed by concentration.

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Abstract

La présente invention concerne un dispositif d'échantillonnage de tissu biologique comprenant : un boîtier formant un corps en forme de barre présentant une longueur dans les directions avant et arrière; un premier support soutenu de manière élastique par un premier ressort hélicoïdal dans un espace interne du boîtier, et présentant une aiguille interne située à son extrémité avant et présentant un espace de réception destiné à recevoir un échantillon biologique; un second support soutenu de manière élastique par un second ressort hélicoïdal dans l'espace interne du boîtier afin d'être ménagé à l'avant du premier support, et présentant une aiguille externe se déplaçant le long de l'aiguille interne dans un état dans lequel l'aiguille externe reçoit l'aiguille interne, afin de fermer l'espace de réception pendant la découpe, par sa partie d'extrémité avant, l'échantillon de tissu étant positionné dans l'espace de réception; un bloc de chargement relié dans l'espace interne du boîtier par une pluralité d'arbres de connexion afin de tirer le premier support et le second support; un levier de chargement accouplé à un arbre articulé formé sur un côté arrière du boîtier, et relié au bloc de chargement se déplaçant le long de l'espace interne du boîtier, de sorte que le levier de chargement tourne autour de l'arbre articulé afin de rétracter le bloc de chargement le long de l'espace; et un levier d'ouverture destiné à rétracter le second support tout en coulissant de l'avant du boîtier vers l'arrière de ce dernier, afin d'ouvrir l'espace de réception d'une première aiguille.
PCT/KR2017/005813 2016-06-03 2017-06-02 Dispositif d'échantillonnage de tissu biologique WO2017209572A1 (fr)

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KR20160069483 2016-06-03

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KR102215655B1 (ko) * 2018-09-06 2021-02-16 주식회사 플라워메디칼 절단 생검기구
KR102384812B1 (ko) * 2018-09-06 2022-04-08 주식회사 플라워메디칼 절단 생검기구
KR102009522B1 (ko) * 2019-02-21 2019-08-09 (주)바이오다인 자궁 검진을 위한 탈락세포 채취장치
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