WO2017116188A3 - 양이온성 지질의 선택적 합성 방법 - Google Patents
양이온성 지질의 선택적 합성 방법 Download PDFInfo
- Publication number
- WO2017116188A3 WO2017116188A3 PCT/KR2016/015525 KR2016015525W WO2017116188A3 WO 2017116188 A3 WO2017116188 A3 WO 2017116188A3 KR 2016015525 W KR2016015525 W KR 2016015525W WO 2017116188 A3 WO2017116188 A3 WO 2017116188A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cationic lipids
- selectively synthesizing
- synthesizing cationic
- selectively
- oligoalkyleneamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/10—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES16882140T ES2887597T3 (es) | 2015-12-30 | 2016-12-29 | Método para sintetizar selectivamente lípidos catiónicos |
EP16882140.3A EP3398932B1 (en) | 2015-12-30 | 2016-12-29 | Method for selectively synthesizing cationic lipids |
CA3009486A CA3009486C (en) | 2015-12-30 | 2016-12-29 | Method for selectively synthesizing cationic lipids |
AU2016382380A AU2016382380B2 (en) | 2015-12-30 | 2016-12-29 | Method for selectively synthesizing cationic lipids |
CN201680077505.5A CN108473417B (zh) | 2015-12-30 | 2016-12-29 | 选择性合成阳离子脂质的方法 |
US15/781,493 US10793516B2 (en) | 2015-12-30 | 2016-12-29 | Method for selectively synthesizing cationic lipids |
JP2018534055A JP2019501915A (ja) | 2015-12-30 | 2016-12-29 | 陽イオン性脂質の選択的合成方法 |
DK16882140.3T DK3398932T3 (da) | 2015-12-30 | 2016-12-29 | Fremgangsmåde til selektiv syntese af kationiske lipider |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020150189843A KR101949453B1 (ko) | 2015-12-30 | 2015-12-30 | 양이온성 지질의 선택적 합성 방법 |
KR10-2015-0189843 | 2015-12-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2017116188A2 WO2017116188A2 (ko) | 2017-07-06 |
WO2017116188A3 true WO2017116188A3 (ko) | 2017-09-14 |
Family
ID=59225232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2016/015525 WO2017116188A2 (ko) | 2015-12-30 | 2016-12-29 | 양이온성 지질의 선택적 합성 방법 |
Country Status (11)
Country | Link |
---|---|
US (1) | US10793516B2 (ko) |
EP (1) | EP3398932B1 (ko) |
JP (1) | JP2019501915A (ko) |
KR (1) | KR101949453B1 (ko) |
CN (1) | CN108473417B (ko) |
AU (1) | AU2016382380B2 (ko) |
CA (1) | CA3009486C (ko) |
DK (1) | DK3398932T3 (ko) |
ES (1) | ES2887597T3 (ko) |
PT (1) | PT3398932T (ko) |
WO (1) | WO2017116188A2 (ko) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040188047A1 (en) * | 2003-03-24 | 2004-09-30 | Nof Corporation | Paper additive composition and method for producing paper using the same |
KR20090088362A (ko) * | 2006-10-03 | 2009-08-19 | 알닐람 파마슈티칼스 인코포레이티드 | 지질 함유 조성물 |
CN104826543A (zh) * | 2015-05-21 | 2015-08-12 | 北京工商大学 | 一种含烷基酰胺乙基的季铵盐Gemini表面活性剂的制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0699376B2 (ja) * | 1990-12-27 | 1994-12-07 | 花王株式会社 | アミドの製造方法 |
US5744355A (en) | 1994-10-18 | 1998-04-28 | Mayo Foundation For Medical Education And Research | cDNA cloning and expression of human liver estrogen sulfotransferase |
AU746589B2 (en) | 1997-07-30 | 2002-05-02 | Monsanto Company | Process and compositions promoting biological effectiveness of exogenous chemical substances in plants |
US6540808B2 (en) * | 2001-04-09 | 2003-04-01 | Mississippi Chemical Corporation | Controlled release fertilizers based on self-assembled molecule coatings |
HUE036916T2 (hu) * | 2004-05-05 | 2018-08-28 | Silence Therapeutics Gmbh | Lipidek, lipid komplexek és ezek alkalmazása |
CN102060723B (zh) * | 2010-11-23 | 2013-03-13 | 湖南师范大学 | 氨基酸阳离子脂质体纳米颗粒的制备方法 |
EP2658577A4 (en) * | 2010-12-30 | 2016-08-24 | Samyang Biopharmaceuticals | CARRIER FOR NEGATIVELY LOADED MEDICAMENTS WITH A CATIONIC LIPID AND METHOD FOR THE PRODUCTION THEREOF |
EP2833869B1 (en) * | 2012-04-04 | 2020-10-28 | Samyang Biopharmaceuticals Corporation | Method of preparing composition for delivering an anionic drug |
-
2015
- 2015-12-30 KR KR1020150189843A patent/KR101949453B1/ko active IP Right Grant
-
2016
- 2016-12-29 WO PCT/KR2016/015525 patent/WO2017116188A2/ko active Application Filing
- 2016-12-29 CA CA3009486A patent/CA3009486C/en active Active
- 2016-12-29 US US15/781,493 patent/US10793516B2/en active Active
- 2016-12-29 CN CN201680077505.5A patent/CN108473417B/zh active Active
- 2016-12-29 DK DK16882140.3T patent/DK3398932T3/da active
- 2016-12-29 JP JP2018534055A patent/JP2019501915A/ja active Pending
- 2016-12-29 EP EP16882140.3A patent/EP3398932B1/en active Active
- 2016-12-29 AU AU2016382380A patent/AU2016382380B2/en active Active
- 2016-12-29 PT PT168821403T patent/PT3398932T/pt unknown
- 2016-12-29 ES ES16882140T patent/ES2887597T3/es active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040188047A1 (en) * | 2003-03-24 | 2004-09-30 | Nof Corporation | Paper additive composition and method for producing paper using the same |
KR20090088362A (ko) * | 2006-10-03 | 2009-08-19 | 알닐람 파마슈티칼스 인코포레이티드 | 지질 함유 조성물 |
CN104826543A (zh) * | 2015-05-21 | 2015-08-12 | 北京工商大学 | 一种含烷基酰胺乙基的季铵盐Gemini表面活性剂的制备方法 |
Non-Patent Citations (2)
Title |
---|
AKINC, A ET AL.: "A Combinatorial Library of Lipid-Like Materials for Delivery of RNAi Therapeutics", NATURE BIOTECHNOLOGY, vol. 26, no. 5, 27 April 2008 (2008-04-27), pages 561 - 569, XP002591574 * |
WHITEHEAD, K. A ET AL.: "Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery", MOL. THER., vol. 19, no. 9, 12 July 2011 (2011-07-12), pages 1688 - 1694, XP055067340 * |
Also Published As
Publication number | Publication date |
---|---|
CN108473417A (zh) | 2018-08-31 |
DK3398932T3 (da) | 2021-11-01 |
KR20170079370A (ko) | 2017-07-10 |
WO2017116188A2 (ko) | 2017-07-06 |
AU2016382380A1 (en) | 2018-07-05 |
EP3398932B1 (en) | 2021-08-11 |
ES2887597T3 (es) | 2021-12-23 |
US10793516B2 (en) | 2020-10-06 |
CN108473417B (zh) | 2021-07-02 |
KR101949453B1 (ko) | 2019-02-18 |
EP3398932A4 (en) | 2019-08-07 |
JP2019501915A (ja) | 2019-01-24 |
US20180346410A1 (en) | 2018-12-06 |
EP3398932A2 (en) | 2018-11-07 |
AU2016382380B2 (en) | 2020-02-06 |
PT3398932T (pt) | 2021-09-06 |
CA3009486A1 (en) | 2017-07-06 |
CA3009486C (en) | 2020-08-25 |
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