WO2017098058A1 - Procédé pour extraire du lactose à partir de lactosérum ou d'un mélange de lactosérum - Google Patents

Procédé pour extraire du lactose à partir de lactosérum ou d'un mélange de lactosérum Download PDF

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Publication number
WO2017098058A1
WO2017098058A1 PCT/EP2016/080703 EP2016080703W WO2017098058A1 WO 2017098058 A1 WO2017098058 A1 WO 2017098058A1 EP 2016080703 W EP2016080703 W EP 2016080703W WO 2017098058 A1 WO2017098058 A1 WO 2017098058A1
Authority
WO
WIPO (PCT)
Prior art keywords
filter screen
porosity
whey
microns
lactose
Prior art date
Application number
PCT/EP2016/080703
Other languages
English (en)
Inventor
Dominick O'reilly
Original Assignee
Dominick O'reilly
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dominick O'reilly filed Critical Dominick O'reilly
Publication of WO2017098058A1 publication Critical patent/WO2017098058A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1422—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C21/00—Whey; Whey preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
    • A23C9/1425—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of whey, e.g. treatment of the UF permeate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K5/00—Lactose
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C2210/00—Physical treatment of dairy products
    • A23C2210/20—Treatment using membranes, including sterile filtration

Definitions

  • the present disclosure relates generally to methods of extracting lactose from whey.
  • FIG. 1 is an embodiment of an apparatus suitable for use with the present disclosure.
  • the present disclosure relates to methods of extracting lactose from whey. Such methods may be used to obtain whey or whey solids with reduced amounts of lactose. High levels of lactose may be problematic to some individuals, such as those suffering from lactose intolerance.
  • the methods described herein may be used to produce whey or whey solids that are suitable for ingestion by those with lactose sensitivities. Methods disclosed herein may also be used to isolate lactose. Products formed by these methods are also disclosed herein.
  • whey is broadly used to refer to liquid byproducts of the manufacture of cheese or other dairy products.
  • whey may refer to liquid remaining after milk has been curdled and strained.
  • solids content refers to the proportion, by weight, of non-volatile material in the whey over the total amount of material in the whey. Unless otherwise stated, all ranges include both endpoints and all numbers between the endpoints.
  • a sample of whey is initially obtained in any suitable fashion, such as by straining milk that has been curdled.
  • Whey typically includes lactose, a disaccharide sugar.
  • lactose may be a solute in a sample of whey.
  • the sample of whey may be heated and slowly cooled. During the cooling stage, lactose may precipitate out of solution.
  • lactose may crystallize as the sample of whey is cooled.
  • the solid (e.g., crystallized) lactose may be removed from the liquid in any suitable manner.
  • the heterogeneous mixture formed upon cooling is centrifuged to pellet the solid lactose.
  • the liquid whey may then be decanted, thereby separating the solid lactose from the liquid.
  • Water may be removed from a sample of whey (e.g., processed or unprocessed whey).
  • a sample of whey may be placed in an evaporator and heated to evaporate off water in the sample.
  • Water may be removed from the sample to achieve a predetermined concentration of solids. For example, in some embodiments, water is removed until the whey has a solids content of between 10% and 80%, between 10% and 50%, between 10% and 30%, between 30% and 80%, between 50% and 80%, between 25% and 60%, or between 35% and 50%.
  • the sample of whey may be cooled.
  • Evaporation of water and subsequent cooling of the sample of whey may result in further precipitation of lactose. Stated differently, evaporation and subsequent cooling may cause lactose crystals to form.
  • whey that has been concentrated by the removal of water may be further processed to separate precipitated lactose from a liquid portion of the whey.
  • the precipitated lactose and the liquid portion of the whey may be placed on one or more filter screens.
  • the screen(s) include a plurality of apertures that are sized to allow liquid to pass through the screen(s) while retaining precipitated lactose as a retentate on the filter screen(s). In this manner, an operator may obtain both a lactose-enriched retentate on the filter screen(s) and a lactose- depleted filtrate.
  • a plurality of filter screens may be used to filter the lactose from the liquid portion of the whey.
  • a plurality of filter screens are arranged in a stacked configuration. More particularly, the filter screens may be arranged such that screens of increased porosity (i.e., having relatively large apertures) are disposed above screens of decreased porosity (i.e., having relatively small apertures). In this manner, as the concentrated whey mixture is placed on the top screen of the plurality of screens, the whey mixture may pass through the screens, with each screen removing smaller lactose-enriched aggregates than the screen directly above it. In this fashion, lactose aggregates (e.g., crystals) of various sizes may be collected.
  • lactose aggregates e.g., crystals
  • screens of differing porosities may be used to filter solid lactose from a liquid portion of a whey concentrate.
  • pore size may vary from 900 microns to 20 microns.
  • a first (e.g., top) screen may have a porosity of 900 microns
  • a second screen may have a porosity of 500 microns
  • a third screen may have a porosity of 300 microns
  • a fourth screen may have a porosity of 200 microns
  • a fifth screen may have a porosity of 00 microns
  • a sixth screen may have a porosity of 50 microns
  • a seventh (e.g., bottom) screen may have a porosity of 20 microns.
  • one or more screens may shake or vibrate as the concentrated whey mixture is filtered. Vibrating the one or more screens may cause the mixture to move on the surface of the screen. Such movement may decrease clogging of the pores of the filter screen, allow different portions of the mixture to contact the surface of the filter screen, and/or increase the speed of filtration.
  • one or more high-frequency vibrating screens may be used.
  • between 50% and 95%, between 50% and 80%, between 50% and 65%, between 65% and 95%, between 80% and 95%, or between 65% and 80% of the lactose in the concentrated whey mixture may be recovered on the filter screens.
  • the lactose precipitate e.g., lactose crystals
  • the lactose precipitate that is recovered as retentate on the one or more filter screens may be between 80% and 95% dry solids (i.e., have a water content of between 5% and 20%). Due to the relatively low water content of this lactose retentate, further drying may be accomplished in a cost- effective manner.
  • the filtering system 100 may also be referred to as a rotary vibrating sieve, sieve shaker, or vibro separator.
  • the system 100 incorporates circular unitary gyratory filter screens used to separate mass composition of solids from solids, and liquid from solid, and for gradation of materials as per particle size. This is accomplished by vibrating the screens in three different planes along the vertical axis by means of a specially designed vibration electric motor 78 having off-centered weights at the top and bottom end of a motor shaft.
  • the system 100 includes a shield 102 or top cover with a feeding inlet 104.
  • the shield 102 may be coupled to a first housing 106 through use of a clamp 108.
  • a first outlet 1 10 communicates with a first interior 1 12 defined by the first housing 106.
  • a first filter screen 1 14 separates the first interior 1 12 from a second interior 1 16 which is defined by a second housing 1 18.
  • a second outlet 120 communicates with the second interior 1 16.
  • a second filter screen 122 separates the second interior 1 16 from a third interior 124 which is defined by a third housing 126.
  • a third outlet 128 communicates with the third interior 124.
  • a third filter screen 130 separates the third interior 124 from a fourth interior 132 which is defined by a fourth housing 134.
  • a fourth outlet 136 communicates with the fourth interior 132.
  • a fourth filter screen 138 separates the fourth interior 132 from a fifth interior 140 which is defined by a fifth housing 142.
  • a fifth outlet 144 communicates with the fifth interior 140.
  • a fifth filter screen 146 separates the fifth interior 140 from a sixth interior 148 which is defined by a sixth housing 150.
  • a sixth outlet 152 communicates with the sixth interior 148.
  • a sixth filter screen 154 separates the sixth interior 148 from a seventh interior 156 which is defined by a seventh housing 158.
  • a seventh outlet 160 communicates with the seventh interior 156.
  • a seventh filter screen 162 separates the seventh interior 156 from an eighth interior 164 which is defined by a eighth housing 166.
  • An eighth outlet 168 communicates with the eighth interior 164.
  • the above-recited elements rest on a platform 170 which is coupled to a plurality of springs 172.
  • the springs 172 are coupled to a base 174 which supports the system 100.
  • a motor housing 176 is coupled to the platform 170 and supports the vibration electric motor 178.
  • the vibration electric motor 178 vibrates the screens 1 14, 122, 130, 138, 146, 154, and 162 in three different planes along the vertical axis.
  • the motor 78 includes a top weight 180 which causes vibration in the horizontal plane and causes the material to move across the screen towards the periphery.
  • the motor 178 includes a lower weight 182 which acts to tilt the system 100 and causes vibration in the vertical tangential axis.
  • the filter screens 1 14, 122, 130, 138, 146, 154, and 162 may vary in pore size from 900 microns to 20 microns.
  • the first filter screen 1 14 may have a porosity of 900 microns
  • the second filter screen 122 may have a porosity of 500 microns
  • the third filter screen 130 may have a porosity of 300 microns
  • the fourth filter screen 138 may have a porosity of 200 microns
  • a fifth filter screen 146 may have a porosity of 100 microns
  • a sixth filter screen 154 may have a porosity of 50 microns
  • a seventh filter screen 162 may have a porosity of 20 microns.
  • the whey mixture is introduced into the inlet 104, and the whey mixture passes through the filter screens 1 14, 122, 130, 138, 146, 154, and 162. Simultaneously, the motor 178 vibrates the filter screens 1 14, 122, 130, 138, 146, 154, and 162, and each proceeding screen removes smaller lactose-enriched aggregates than the subsequent screen. Lactose aggregates of various sizes exit out of corresponding outlets 1 10, 120, 128, 136, 144, 152, 160, and 168 where they may be collected and stored. [0026] Any methods disclosed herein include one or more steps or actions for performing the described methods. The method steps and/or actions may be interchanged with one another.

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Dairy Products (AREA)

Abstract

La présente invention concerne des procédés d'extraction de lactose à partir de lactosérum. Lesdits procédés peuvent comprendre l'élimination de l'eau à partir du lactosérum, provoquant ainsi la précipitation de lactose depuis le lactosérum. Le mélange hétérogène obtenu peut être filtré par un ou plusieurs filtres vibrants pour séparer le lactose solide de la partie liquide du lactosérum. La présente invention concerne également des produits apparentés, tels que le rétentat enrichi en lactose et le filtrat appauvri en lactose, obtenus par lesdits procédés.
PCT/EP2016/080703 2015-12-10 2016-12-12 Procédé pour extraire du lactose à partir de lactosérum ou d'un mélange de lactosérum WO2017098058A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562265871P 2015-12-10 2015-12-10
US62/265,871 2015-12-10

Publications (1)

Publication Number Publication Date
WO2017098058A1 true WO2017098058A1 (fr) 2017-06-15

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PCT/EP2016/080703 WO2017098058A1 (fr) 2015-12-10 2016-12-12 Procédé pour extraire du lactose à partir de lactosérum ou d'un mélange de lactosérum

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112744962A (zh) * 2020-12-14 2021-05-04 安徽国星生物化学有限公司 一种高盐含氰废水处理用盐分提取装置及其提取工艺

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423208A (en) * 1965-02-22 1969-01-21 Josef A Meggle Method of precipitating casein from milk
US3535784A (en) * 1968-12-09 1970-10-27 Dairy Equipment Co Apparatus for continuously separating curd fines from whey
WO2014141164A1 (fr) * 2013-03-15 2014-09-18 Paul Stephenson Récupération de lactose
WO2015099960A1 (fr) * 2013-12-24 2015-07-02 Wimm-Bill-Dann Foods Ojsc Sel de laiterie, procédé pour le produire et produits alimentaires le contenant

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423208A (en) * 1965-02-22 1969-01-21 Josef A Meggle Method of precipitating casein from milk
US3535784A (en) * 1968-12-09 1970-10-27 Dairy Equipment Co Apparatus for continuously separating curd fines from whey
WO2014141164A1 (fr) * 2013-03-15 2014-09-18 Paul Stephenson Récupération de lactose
WO2015099960A1 (fr) * 2013-12-24 2015-07-02 Wimm-Bill-Dann Foods Ojsc Sel de laiterie, procédé pour le produire et produits alimentaires le contenant

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CECILIA HODÚR ET AL: "Comparison of 3DTA and VSEP systems during the ultrafiltration of sweet whey", DESALINATION AND WATER TREATMENT : SCIENCE AND ENGINEERING ; DWT, vol. 10, no. 1-3, 3 October 2009 (2009-10-03), UK, pages 265 - 271, XP055359838, ISSN: 1944-3994, DOI: 10.5004/dwt.2009.927 *
JAFFRIN ET AL: "Dynamic shear-enhanced membrane filtration: A review of rotating disks, rotating membranes and vibrating systems", JOURNAL OF MEMBRANE SCIENCE, ELSEVIER BV, NL, vol. 324, no. 1-2, 31 October 2008 (2008-10-31), pages 7 - 25, XP024525125, ISSN: 0376-7388, [retrieved on 20080628], DOI: 10.1016/J.MEMSCI.2008.06.050 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112744962A (zh) * 2020-12-14 2021-05-04 安徽国星生物化学有限公司 一种高盐含氰废水处理用盐分提取装置及其提取工艺

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