WO2017090886A1 - Appareil de stimulation électrique de type timbre apte à l'administration de médicament et son procédé de commande - Google Patents

Appareil de stimulation électrique de type timbre apte à l'administration de médicament et son procédé de commande Download PDF

Info

Publication number
WO2017090886A1
WO2017090886A1 PCT/KR2016/011350 KR2016011350W WO2017090886A1 WO 2017090886 A1 WO2017090886 A1 WO 2017090886A1 KR 2016011350 W KR2016011350 W KR 2016011350W WO 2017090886 A1 WO2017090886 A1 WO 2017090886A1
Authority
WO
WIPO (PCT)
Prior art keywords
drug
electrical signal
conductive pattern
region
body portion
Prior art date
Application number
PCT/KR2016/011350
Other languages
English (en)
Korean (ko)
Inventor
유한실
유화진
이주희
Original Assignee
유한실
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 유한실 filed Critical 유한실
Publication of WO2017090886A1 publication Critical patent/WO2017090886A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes

Definitions

  • the present application relates to a patch electrode, a patch type electrical stimulation device and a control method thereof.
  • the electricity generated from the electrical stimulation device is transferred to the user's body through the gel adhesive layer between the patch and the skin so that the electrical stimulation treatment is performed.
  • a patch type electrical stimulation device is widely used for the treatment of obesity or pain in the form of stimulating the menstrual blood of the body through the microcurrent.
  • such a patch type electrical stimulation device is not expected to have an effect other than the therapeutic effect by the electrical stimulation is delivered to the user's body.
  • the effect of the treatment is insignificant only by applying a simple electric stimulation depending on the treatment purpose or the lesion.
  • the present invention is to solve the above-mentioned problems of the prior art, to provide a patch-type electrode, a patch-type electrical stimulation device and a method of controlling the same to enable the treatment by the electrical stimulation and the treatment with the drug at the same time.
  • the present application is to provide a patch-type electrode, a patch-type electrical stimulation device and a control method for enabling both passive drug delivery and active drug delivery.
  • the present application is to provide a patch-type electrode, a patch-type electrical stimulation device and a control method capable of operating the electrical signal for the electrical stimulation and the electrical signal required for drug delivery by iontophoresis.
  • the present application is to provide an effective coupling structure between a patch-type electrode capable of electrical stimulation and drug stimulation, and an electrical signal generator for generating an electrical signal required for each of electrical stimulation and drug stimulation.
  • the patch-type electrical stimulation device is formed in the body portion, the first region of the body portion, the electrical signal generated by the electrical signal generation unit electrode portion
  • the conductive pattern may be transmitted to the electrode unit to generate an electrical stimulation based on the electrical signal and the second portion of the body portion, and may include a drug portion including a drug.
  • the conductive pattern may be a first conductive pattern, and may further include a second conductive pattern formed between the second region of the body portion and the drug portion.
  • the electrical signal may be a first electrical signal
  • the second conductive pattern may transfer a second electrical signal generated by the electrical signal generator.
  • the second electrical signal may cause the drug to be released by iontophoresis.
  • the drug is a first drug
  • the drug portion may be a first drug portion, and formed in a third region of the body portion, and may further include a second drug portion including a second drug.
  • a third conductive pattern may be further formed between the third region of the body portion and the second drug portion to transfer the third electrical signal generated by the electrical signal generator.
  • the first drug may be cationized to be released by the second electrical signal
  • the second drug may be anionized to be released by the third electrical signal.
  • the electrode part may include a plurality of sub-electrode parts, and each of the first drug part and the second drug part may include a plurality of sub drug parts.
  • at least two of the plurality of sub-electrode parts and the plurality of sub-drug parts may be physically or electrically separated from each other.
  • the plurality of sub drug units may be formed to be disposed adjacent to (or side by side) at intervals.
  • the conductive pattern may be formed to be stacked on the first region of one surface of the body portion, and the drug portion may be formed to be stacked on the second region of one surface of the body portion.
  • the first region may be an intermediate region of the body portion, and the second region may be a region surrounding the first region.
  • At least two of the first conductive pattern, the second conductive pattern, and the third conductive pattern may be electrically separated from each other.
  • the electronic signal generating unit may further include a connection unit for transmitting the electric signal to the conductive pattern.
  • one end is exposed to one surface of the body portion, the other end is exposed to the other surface of the body portion, and is connected to a part of the electrical signal generator through the one end, and through the other end It may be connected with a portion of the conductive pattern.
  • connection part is magnetic and may be connected to a part of the electric signal generation by the magnetism.
  • connection part may include at least one sub connection part, and each of the at least one sub connection part may be connected to the conductive pattern or the electrode part.
  • the electronic signal generator may further include an electric signal generator.
  • any one of the type, magnitude, period or polarity of the first electrical signal may be different from any one of the type, magnitude, period or polarity of the second electrical signal.
  • the second electrical signal may be determined based on the first electrical signal.
  • the electrical signal generator may determine on or off of at least one of the sub connection units.
  • the electrical signal generator may determine on or off of at least one of the sub connection units periodically or sequentially.
  • the electrical signal generator determines on or off of any one of the sub-connecting units based on the on or off of the other one of the sub-connecting units. Can be.
  • the first electrical signal may be an AC electrical signal
  • the second electrical signal may be a DC electrical signal
  • the patch-type electrode according to an embodiment of the present embodiment is formed in the body portion, the first region of the body portion, and transfers an electrical signal generated by the electrical signal generator to the electrode portion
  • the conductive pattern may include an electrode portion for generating an electrical stimulation based on the electrical signal and a second portion of the body portion, the drug portion including a drug.
  • the control method of the patch type electrical stimulation apparatus the electrical signal generator, the first electrical signal corresponding to the electrode portion of the patch type electrical stimulation apparatus Generating and transmitting the first electrical signal to the electrode through a first conductive pattern formed in a first region of the body portion of the patch type electrical stimulation device, wherein the patch type electrical stimulation device includes a second portion of the body portion; It may include a drug moiety formed in the region and including a drug.
  • generating the second electrical signal corresponding to the drug portion of the patch-type electrical stimulation device and the second electrical through the second conductive pattern formed in the second area of the body portion of the patch-type electrical stimulation device may further include transmitting a signal to the drug unit.
  • the present application may include both a passive drug delivery and an active drug delivery by including a first drug portion including an active drug and a second drug portion for iontophoresis.
  • the present application may generate an electrical signal for the electrical stimulation and the electrical signal required for drug delivery by iontophoresis through the electrical signal generator, and may be delivered to each of the electrode portion and the drug portion.
  • the present application can provide an effective coupling structure between the patch-type electrode capable of electrical stimulation and drug stimulation, and the electrical signal generator for generating an electrical signal required for each of the electrical stimulation and drug stimulation. .
  • FIG. 1 is a view showing a patch type electrical stimulation device according to an embodiment of the present application.
  • FIG. 1 is an exploded perspective view of FIG. 1.
  • FIG. 3 is a view showing a patch type electrical stimulation device according to another embodiment of the present application.
  • FIG. 4 is an exploded perspective view of FIG. 3.
  • FIG. 5 is a view showing a patch type electrical stimulation device according to another embodiment of the present application.
  • FIG. 6 is an exploded perspective view of FIG. 5.
  • connection unit 7 is a view for explaining an example of the connection unit and the electrical signal generator of the present application.
  • FIG. 8 is a view showing a patch type electrical stimulation device according to another embodiment of the present application.
  • FIG. 9 is a view for explaining an example of the arrangement of the first drug unit and the second drug unit of the present application.
  • FIG. 10 is an operation flowchart of a control method of a patch type electrical stimulation apparatus according to an embodiment of the present application.
  • the term 'part' or 'means' includes units realized by hardware, units realized by software, and units realized by both.
  • one unit may be realized using two or more pieces of hardware, and two or more units may be realized by one piece of hardware.
  • the patch type electrical stimulation apparatus of the present application may be attached to a subject to provide an electrical stimulus and a drug stimulus to the subject.
  • the patch-type electrical stimulation device of the present application may include a drug portion including the electrode and the drug generating an electrical stimulation based on the electrical signal.
  • the patch type electrical stimulation device of the present application may further include a conductive pattern for transmitting an electrical signal to the electrode portion.
  • the patch type electrical stimulation device may further include an electrical signal generator for generating an electrical signal.
  • the patch type electrical stimulation device may be represented as a patch type electrode.
  • the patch type electrode includes the electrode portion, the drug portion, and the conductive pattern described above, and the patch type electrical stimulation device may be a patch type electrode. It may include an electrical signal generator.
  • the patch type electrical stimulation apparatus of the present application is not limited only to the description of the drawings below.
  • the shape and number of the conductive pattern, the shape of the electrode part, the shape and function of the drug part, the number and arrangement shape of the connection part to be described later may depend on the part of the object to which the patch type electrical stimulation device is to be used. Various decisions can be made.
  • the patch type electrical stimulation device may include an electrode portion and a passive drug portion.
  • the patch type electrical stimulation device may include an electrode portion and an active (or iontophoretic) drug portion.
  • the patch type electrical stimulation device may include an electrode portion, the first drug portion and the second drug portion.
  • the first drug moiety may be a passive drug moiety while the second drug moiety may be an active drug moiety, while the first drug moiety may be the first active drug moiety, the second drug moiety may be a second active drug moiety, and the first drug moiety may be the first drug moiety. While being a passive drug moiety, the second drug moiety may be a second passive drug moiety.
  • FIG. 1 is a view showing a patch type electrical stimulation device according to an embodiment of the present application.
  • 2 is an exploded perspective view of FIG. 1.
  • a patch type electrical stimulation device according to an exemplary embodiment of the present disclosure will be described with reference to FIGS. 1 and 2.
  • Patch type electrical stimulation device 100 may include a body portion 110, a conductive pattern 121, an electrode portion 140 and the drug portion 130.
  • the conductive pattern 121 may be formed in the first region 111 of the body portion 110.
  • the conductive pattern 121 may transmit the electrical signal generated by the electrical signal generator (not shown) to the electrode unit 140.
  • the conductive pattern 121 may include a pair of sub conductive patterns.
  • the conductive pattern 121 is a pattern made of a conductor, and may be directly patterned on the back of the electrode unit 140, and may be printed on a region of the body unit 110 through, for example, carbon, gold, or silver paste. It may be thin film patterned (or in the form of a patterned thin film) or plated through a metal material such as, for example, gold, copper, nickel, zinc, nickel silver, silver or the like.
  • the conductive pattern 121 may be a conductive plastic, a conductive rubber, a conductive fabric is cut directly to the pattern forming and bonded to the body portion 110.
  • the electrode unit 140 may generate an electrical stimulus based on the electrical signal.
  • the electrode unit 140 may include an adhesive layer for adhesion (or contact) with the skin of the object (eg, the body) on one surface.
  • the adhesive layer may be formed in a gel form, an example of the gel may be a hydrogel.
  • the electrode unit 140 may be formed of metals having excellent electrical conductivity.
  • One example of the material of the electrode unit 140 may be conductive metals such as gold, copper, nickel, zinc, nickel silver, and silver, but is not limited thereto.
  • the electrode unit 140 may be a patch type electrode patch.
  • the drug unit 130 may include a drug.
  • the drug unit 130 may be formed in the second region 112 of the body unit 110.
  • the drug unit 130 may be passive.
  • the passive type may mean that the drug is naturally diffused to the subject.
  • a drug contained in (or applied to) the passive drug moiety may be a pars-associated drug such as plata or cataplasma, and such drug may be diffused into the subject's skin by concentration.
  • the drug unit 130 may be a patch type drug patch.
  • the conductive pattern 121, the electrode unit 140, and the drug unit 130 described above may be formed on one surface of the body 110.
  • a body portion 110 may be formed in a patch shape, the shape, thickness, material, etc. may be variously determined according to the portion of the object to be applied or bonded.
  • One example of the material of the body portion 110 may be woven fabric, nonwoven fabric, paper, for example silicone elastomer, rubber such as polyurethane, for example, liquid crystal polymer, polyimide, plastic such as polyethylene terephthalate (PET).
  • PET polyethylene terephthalate
  • the present invention is not limited thereto.
  • the conductive pattern 121 may be formed in the first region 111 of the body portion 110, and the drug portion 130 may be formed in the second region 112 of the body portion 110.
  • the conductive pattern 121 is formed to be stacked on the first region 111 of one surface of the body portion 110 (for example, a lower surface or a surface in a direction in contact with the skin of the object) and the drug portion 130. ) May be formed to be stacked on the second area 112 of one surface of the body 110 (for example, a lower surface or a surface in a direction in contact with the skin of the object).
  • the first region 111 may be physically or electrically separated from the second region 112.
  • the first region 111 may be a body portion 110 or an intermediate region of one surface of the body portion 110, and the second region 112 may be a region surrounding the first region 111.
  • the patch type electrical stimulation device 100 may further include an electrical signal generator (not shown) that generates an electrical signal.
  • the electric signal generator (not shown) may supply an electric signal to the conductive pattern 121 or the electrode unit 140, and may variously determine the type, size, time, period, etc. of the electric signal.
  • the electrical signal generator may generate various electrical signals corresponding to the stimulation mode (or type, type) of the electrical stimulation generated through the electrode unit 140.
  • the stimulation mode may be tapping, kneading, strong kneading, combination stimulation, and the various stimulation signals may be different to enable each of the stimulation mode.
  • the electrical signal generator may include residual electric discharge, electrode detachment detection, and a gradual sensitivity increase function.
  • the residual electric discharge may mean a function of releasing residual electricity when the power of the patch-type electrical stimulation device 100 or the electric signal generator (not shown) is turned off to prevent shock due to residual electricity in the next use.
  • the electrode detachment detection monitors an electrical connection between an electrical signal generator (not shown) and at least two of a connection unit (not shown), an electrode unit 140, or a skin of an object, for example, an electrical signal.
  • the electrical connection such as the electrode portion 140 and the end of the adhesion of the skin of the object, it may mean that a warning sound is generated.
  • the user's discomfort or shock due to the movement of the electrode unit 140 or the detachment of the electrode unit 140 due to an unintended situation can be prevented.
  • the gradual increase in intensity causes the electrical signal generator (not shown) or the main body to remember the stimulation mode and the set intensity and wait for reconnection, and suddenly resume the stimulation by reconnection. It may mean a function of gradually increasing the stimulus intensity (for example, about 1 step per 1.5 seconds) gradually from the 0 step to the previous setting step without stimulating with the stimulus intensity which is set in a smooth manner. Through this, surprise of the user due to sudden electric stimulation due to restimulation can be prevented.
  • the electrical signal generator may include a battery therein, and the battery may be charged based on a USB cable or wireless connection between the electrical signal generator (not shown) and a computer or mobile phone charger.
  • a battery may be a safe polymer battery, and may have a lifespan capable of charging and discharging more than 500 to thousands of times with only one charge, within about 1.5 hours of a buffering use time.
  • the electrical signal generator (not shown) may be magnetically connected to a connection unit (not shown) to be described later. Through this, detachment and reattachment between the electric signal generator (not shown) and the connection unit (not shown) are easy, and various types of electrodes can be applied according to a user's attachment site.
  • the patch type electrical stimulation device 100 may further include a connection unit (not shown) for transmitting the electrical signal generated by the electrical signal generator (not shown) to the conductive pattern 121.
  • a connection unit for transmitting the electrical signal generated by the electrical signal generator (not shown) to the conductive pattern 121.
  • One end of the connection part (not shown) is exposed to one surface (for example, a lower surface or a surface in a direction of contact with the skin of the object) of the body part 110, and the other surface of the body part 110 (for example, The other end may be exposed to the upper surface or the surface in the opposite direction in contact with the skin of the object, and may be connected to a part of the electrical signal generator (not shown) through one end and may be connected to a part of the conductive pattern 121 through the other end. .
  • connection portion has a magnetic, it can be electrically or physically connected to a portion of the electrical signal generator (not shown) by the magnetic.
  • connection part may include at least one sub connection part, and each of the at least one sub connection part may be connected to the conductive pattern 121 or the electrode part 140.
  • FIG. 3 is a view showing a patch type electrical stimulation device according to another embodiment of the present application.
  • 4 is an exploded perspective view of FIG. 3.
  • a patch type electrical stimulation device according to another embodiment of the present disclosure will be described with reference to FIGS. 3 and 4.
  • the descriptions omitted may be applied mutatis mutandis as described above with reference to FIGS. 1 and 2.
  • the connection unit 250 is omitted, the description of the connection unit described with reference to FIGS. 1 and 2 can be applied mutatis mutandis.
  • the patch type electrical stimulation device 200 may include a body portion 210, a conductive pattern 220, a drug portion 230, and an electrode portion 240.
  • the conductive pattern 220 may include a first conductive pattern 221 and a second conductive pattern 222.
  • the first conductive pattern 221 may be formed in the first region 211 of the body portion 110.
  • the first conductive pattern 221 may transmit the first electrical signal generated by the electrical signal generator (not shown) to the electrode unit 240.
  • the first conductive pattern 221 may include a pair of sub conductive patterns. The description of the first conductive pattern 221 and the second conductive pattern 222 is replaced with the description of the conductive pattern 111.
  • the second conductive pattern 222 may be formed between the second region 212 and the drug portion 230 of the body portion.
  • the second conductive pattern 222 may transfer the second electrical signal generated by the electrical signal generator (not shown).
  • the second conductive pattern 222 may transmit the second electrical signal to the drug unit 230.
  • the second electrical signal may cause the drug contained in the drug unit 230 to be released by iontophoresis.
  • the electrode unit 240 may generate an electrical stimulus based on the first electrical signal.
  • the electrode unit 240 may include an adhesive layer for adhesion (or contact) with the skin of the object (eg, the body) on one surface.
  • the adhesive layer may be formed in a gel form, an example of the gel may be a hydrogel.
  • the description of the electrode unit 240 is replaced with the description of the electrode unit 140.
  • the drug unit 230 may include a drug.
  • the drug unit 130 may be formed to be stacked on the second conductive pattern 222.
  • the drug unit 230 may be active.
  • the active type may be expressed as iontophoretic type.
  • the iontophoretic drug moiety may be a patch coated or contained with an ionized material (eg, a drug) to enable iontophoresis.
  • Iontophoresis may mean that the ionized drug is diffused into the subject in response to an electrical signal.
  • the drug ionized by the anode may be diffused into the inside of the object (eg, inside the skin) according to iontophoresis by the electrical signal of the anode.
  • the drug unit 230 may be a patch type drug patch.
  • any one of the type (eg, alternating current or direct current type), magnitude, period, or polarity of the first electric signal may be the type of the second electric signal (eg alternating current or direct current type). It may be different from either one.
  • the first electrical signal may be an alternating current (or pulsed) electrical signal
  • the second electrical signal may be a direct current (or monopolar) electrical signal.
  • the second electrical signal may be determined based on the first electrical signal.
  • any one of the type (eg, alternating current or direct current type), magnitude, period, or polarity of the second electrical signal may be the type (eg, alternating current or direct current type), magnitude, period, or polarity of the first electrical signal. Can be determined based on either of the polarities.
  • the type of the second electric signal may be determined as a direct current type when the first electric signal is an alternating current type, and may be determined as an alternating current type when the first electric signal is a direct current type.
  • the magnitude of the second electrical signal may be determined based on the magnitude of the first electrical signal.
  • the time interval at which the second electrical signal is generated may be determined to partially or not overlap the time interval at which the first electrical signal is generated, in consideration of the time interval at which the first electrical signal is generated.
  • the first electrical signal may be determined based on the second electrical signal.
  • the first conductive pattern 221, the second conductive pattern 222, the electrode portion 240, and the drug portion 230 described above may be formed on one surface of the body portion 210.
  • the body portion 210 may be formed in a patch shape, and its shape, thickness, material, and the like may be variously determined according to a portion of the object to be applied or bonded.
  • One example of the material of the body portion 210 may be woven fabric, nonwoven fabric, paper, for example silicone elastomer, rubber such as polyurethane, for example, liquid crystal polymer, polyimide, plastic such as polyethylene terephthalate (PET).
  • PET polyethylene terephthalate
  • the present invention is not limited thereto.
  • the first conductive pattern 221 is formed in the first region 211 of the body portion 210, and the second conductive pattern 222 is the second region 212 of the body portion 210.
  • the first conductive pattern 221 is formed to be laminated on the first region 211 of one surface (eg, the lower surface or the surface in the direction of contact with the skin of the object) of the body portion 210
  • the second The conductive pattern 222 may be formed to be stacked on the second region 212 of one surface of the body portion 210 (for example, a bottom surface or a surface in a direction in contact with the skin of the object).
  • the second region 211 may be physically or electrically separated from the second region 212.
  • the first region 211 may be a body portion 210 or an intermediate region of one surface of the body portion 210
  • the second region 212 may be a region surrounding the first region 211.
  • the patch type electrical stimulation device 200 may further include an electrical signal generator (not shown) for generating an electrical signal.
  • the electrical signal generator (not shown) supplies the first electrical signal or the second electrical signal to the first conductive pattern 221 or the second conductive pattern 222, and the type, size, time, and period of such electrical signals. And so on.
  • An additional description of such an electric signal generator (not shown) is to replace the electric signal generator (not shown) described above with reference to FIG. 1.
  • the patch type electrical stimulation device 200 may include a connection part 250.
  • the connection part 250 has one end exposed to one surface of the body portion 210 (for example, a lower surface or a surface in a direction in contact with the skin of the object), and the other surface of the body portion 210 (for example, the upper surface or the object). The other end is exposed to the surface in contact with the skin of the opposite direction), is connected to a part of the electrical signal generator (not shown) through one end, and the first conductive pattern 221 and the second conductive pattern 222 are connected through the other end.
  • connection part 250 may have a magnetic property, and may be electrically or physically connected to a part of the electric signal generator (not shown) by the magnetism.
  • the connection part 250 may include at least one sub connection part, and each of the at least one sub connection part may be connected to each of the first conductive pattern 221, the second conductive pattern 222, or the electrode part 140.
  • the connection part 250 includes three sub connection parts, the first sub connection part is connected with the first sub first conductive pattern, the second sub connection part is connected with the second sub first conductive pattern, and The three sub-connections may be connected to the second conductive pattern 222.
  • the electrical signal generator may determine the on (On) or off (Off) of at least one of the sub connection.
  • the electrical signal generator may determine on or off of at least one of the electrical signals provided to each of the sub-connectors.
  • the electrical signal generator may include a pair of subs of the first electrical signal or the first conductive pattern 221 which is involved in the operation of the first sub-electrode part of the pair of sub-electrode parts of the electrode part 240.
  • the first electrical signal related to the operation of the first sub-conductive pattern of the first conductive pattern may be turned off, and the second electrical signal related to the operation of the second conductive pattern 222 or the drug unit 230 may be turned on. .
  • the electric signal generator may periodically or sequentially determine at least one of On or Off of the sub connection units.
  • the electrical signal generator may periodically or sequentially determine at least one of On or Off of the electrical signals provided to each of the sub-connectors.
  • the electrical signal generator may determine to alternate on or off of at least one of the sub-connectors.
  • the electrical signal generator (not shown) is turned on (On) or off (Off) of any one of the sub-connecting portion On or Off of the other of the sub-connecting portion (On) Can be determined based on.
  • the electrical signal generator (not shown) may turn off the second sub-connector while the first sub-connector is on, and turn on the second sub-connector while the first sub-connector is off.
  • the electrical signal generator (not shown) may determine whether the first sub-connector is on, and when the determination results in operation, when the first sub-connector is on, the second sub-connector may be turned on.
  • the electrical signal generator (not shown) determines whether the on state of the first sub-connector has exceeded the threshold time interval, and, when the on state of the first sub-connector has exceeded the threshold time interval, the second The sub connection can also be turned on.
  • FIG. 5 is a view showing a patch type electrical stimulation device according to another embodiment of the present application.
  • 6 is an exploded perspective view of FIG. 5.
  • a patch type electrical stimulation device according to another embodiment of the present disclosure will be described with reference to FIGS. 4 and 5.
  • the description omitted may apply mutatis mutandis as described above with reference to FIGS. 1 to 4.
  • the description of the connection unit described above with reference to FIGS. 1 to 4 may apply mutatis mutandis.
  • Patch type electrical stimulation device 300 may include a body portion 310, the conductive pattern 320, the drug portion 330, the electrode portion 340 and the connection portion 350.
  • the conductive pattern 320 may include a first conductive pattern 321, a second conductive pattern 322, and a third conductive pattern 323.
  • the drug unit 330 may include a first drug unit 322 and a second drug unit 323.
  • the first conductive pattern 321 may be formed in the first region 311 of the body portion 310.
  • the first conductive pattern 321 may transmit the first electrical signal generated by the electrical signal generator (not shown) to the electrode unit 340.
  • the first conductive pattern 321 may include a pair of sub conductive patterns. The description of the first conductive pattern 321 and the third conductive pattern 323 is replaced with the description of the various conductive patterns described above with reference to FIGS. 1 to 4.
  • the second conductive pattern 322 may be formed between the second region 312 and the first drug portion 322 of the body portion 310.
  • the second conductive pattern 322 may transfer a second electric signal generated by an electric signal generator (not shown).
  • the second conductive pattern 322 may transfer the second electrical signal to the first drug unit 332.
  • the second electrical signal may cause the drug contained in the first drug unit 332 to be released by iontophoresis.
  • the third conductive pattern 323 may be formed between the third region 313 of the body portion 310 and the second drug portion 323.
  • the third conductive pattern 323 may transfer the third electrical signal generated by the electrical signal generator (not shown).
  • the third conductive pattern 323 may transmit the third electrical signal to the second drug unit 333.
  • the third electrical signal may cause the drug contained in the second drug unit 333 to be released by iontophoresis.
  • At least two of the first conductive pattern 321 and the second conductive pattern 322 may be physically or electrically separated from each other.
  • any one of the second conductive pattern 322 or the third conductive pattern 323 may be omitted in FIGS. 5 and 6.
  • either the first drug portion 332 corresponding to the second conductive pattern 322 or the second drug portion 333 corresponding to the third conductive pattern 323 is a passive drug portion
  • the other of the first drug portion 332 corresponding to the pattern 322 or the second drug portion 333 corresponding to the third conductive pattern 323 may be an active drug portion.
  • the electrode unit 340 may generate an electrical stimulus based on the first electrical signal.
  • the electrode unit 340 may include an adhesive layer for adhesion (or contact) with the skin of an object (eg, a body) on one surface. As such, the description of the electrode unit 340 is replaced with the description of the various electrode units described with reference to FIGS. 1 to 4.
  • the drug unit 330 may include a drug.
  • the first drug unit 332 may include the first drug
  • the second drug unit 333 may include the second drug.
  • the first drug part 332 may be formed to be stacked on the second conductive pattern 322
  • the second drug part 333 may be formed to be stacked on the third conductive pattern 323.
  • both the first drug portion 332 and the second drug portion 333 may be active.
  • the first drug and the second drug may be different from each other.
  • the first drug may be cationized to be released by the second electrical signal
  • the second drug may be anionized to be released by the third electrical signal.
  • the active type can be expressed as iontophoretic.
  • the iontophoretic drug moiety may be a patch coated or contained with an ionized material (eg, a drug) to enable iontophoresis.
  • the first drug unit 332 and the second drug unit 333 may be a patch type drug patch.
  • the first drug portion 332 may be a passive drug portion, and the second drug portion 333 may be an active drug portion.
  • the first drug unit 332 may include a first drug that is naturally released, and the second drug unit 333 may include a second drug that is released by iontophoresis.
  • reference numeral 333 may be a second electrode unit.
  • the second electrode unit may include a drug.
  • the second electrode unit may be configured to have a relatively small area so that the electrical impedance is lower than the first drug unit 332.
  • the type of the third electrical signal of the second electrode unit may be different from the type of the second electrical signal corresponding to the first drug unit 332.
  • the third electrical signal may be an alternating current type
  • the second electrical signal may be a direct current type.
  • any one of the type (eg, alternating current or direct current type), magnitude, period, or polarity of the first electrical signal may be the type of the second electrical signal (eg alternating current or direct current type).
  • a third type of electrical signal for example, AC or DC
  • the first electrical signal may be an alternating current (or pulsed) electrical signal
  • the second electrical signal and the third electrical signal may be a direct current (or single pole) electrical signal
  • the second electrical signal may be a direct current (or unipolar) electrical signal of a positive pole
  • the third electrical signal may be a direct current (or unipolar) electric signal of a negative pole.
  • the first drug may be a cationized drug so as to be emitted by the direct current type electrical signal of the positive electrode
  • the second drug may be an anionized drug to be emitted by the direct current type electric signal of the negative electrode.
  • any one of the first electrical signal to the third electrical signal may be determined based on the other of the first electrical signal to the third electrical signal.
  • any one of the type (eg, alternating current or direct current type), the magnitude, the period, or the polarity of the first electrical signal to the third electrical signal is one of the other of the first electrical signal to the third electrical signal. It can be determined based on any one of the type (eg, alternating current or direct current type), magnitude, period, or polarity.
  • the type of the third electric signal may be determined as a direct current type when the first electric signal is an alternating current type, and may be determined as an alternating current type when the first electric signal is a direct current type.
  • the magnitude of the second electrical signal may be determined based on the magnitude of the first electrical signal.
  • the time interval at which the third electrical signal is generated may be determined to partially or not overlap the time interval at which the second electrical signal is generated, in consideration of the time interval at which the second electrical signal is generated.
  • One surface of the body part 310 may include the first conductive pattern 321, the second conductive pattern 322, the third conductive pattern 323, the electrode part 340, the first drug part 332, and the like.
  • the second drug unit 333 may be formed.
  • Such a body portion 310 may be formed in a patch shape, the shape, thickness, material, etc. may be variously determined according to the portion of the object to be applied or bonded.
  • the first conductive pattern 321 is formed in the first region 311 of the body portion 310
  • the second conductive pattern 322 is the second region 312 of the body portion 310
  • the third conductive pattern 323 may be formed in the third region 313 of the body portion 310.
  • the first conductive pattern 321 is formed to be laminated on the first region 311 of one surface of the body portion 310 (for example, the lower surface or the surface in the direction in contact with the skin of the object), and the second The conductive pattern 322 is formed to be stacked on the second region 312 of one surface of the body portion 310 (for example, a bottom surface or a surface in a direction in contact with the skin of the object), and the third conductive pattern 323
  • the silver may be formed to be stacked on the third region 313 of one surface of the body 310 (eg, a lower surface or a surface in a direction in contact with the skin of the object).
  • the first region 311 to the third region 313 may be physically or electrically separated from each other.
  • the first region 311 and the third region 313 are the body portion 310 or an intermediate region of one surface of the body portion 310
  • the second region 312 is the first region 311 and the third region. It may be an area surrounding the area 313.
  • the patch type electrical stimulation device 300 may further include an electrical signal generator 370 for generating an electrical signal.
  • the electrical signal generator 370 supplies the first electrical signal to the third electrical signal to each of the first conductive pattern 321 to the third conductive pattern 323, and the type, size, time, The frequency can be determined in various ways.
  • the additional description of the electrical signal generator 370 is for the electrical signal generator 370 described above with reference to FIGS. 1 to 4.
  • the patch type electrical stimulation device 300 may include a connection 350.
  • the connection portion 350 has one end exposed to one surface of the body 310 (for example, a lower surface or a surface in a direction in contact with the skin of the object), and the other surface of the body 310 (for example, the upper surface or the object). The other end is exposed to the surface in contact with the skin of the opposite direction), is connected to a part 361 of the electrical signal generator 370 through one end, and the first conductive pattern 321 to the third conductive pattern through the other end. 323 may be connected with each part.
  • the part 361 may be combined with the connection unit 350.
  • the connection part 350 may include a shape of a button which is a convex surface of a snap button (or a snap button), and a part 361 may include a shape of a female button that is a concave surface.
  • the connection unit 350 is magnetic, and may be electrically or physically connected to a part 361 of the electrical signal generator 360 by the magnetism.
  • the connection method of the electrical signal generator 360 includes a physical coupling type and a magnet coupling type.
  • the physical coupling type is to be combined in the form of a snap button
  • the magnet coupling type is that the connection portion 350 may be a metal riveted form, the magnet is included in a portion (or connector) of the electrical signal generator 360 There may be an electrical connection by the magnetic force.
  • the connection part 350 may include at least one sub connection part, and each of the at least one sub connection part may be connected to each sub part of the portion 361.
  • each of the sub-connections may be a means button shape that is a convex surface of a snap button (or a snap button)
  • each of the sub-parts may be a female button shape that is a concave surface of a snap button (or a snap button).
  • each of the at least one sub connection part may be connected to each of the first conductive pattern 321, the second conductive pattern 322, the third conductive pattern 323, or the electrode unit 140.
  • the connection part 350 includes four sub connection parts, the first sub connection part is connected with the first sub first conductive pattern, the second sub connection part is connected with the second sub first conductive pattern, and the third sub connection part is the second sub connection part.
  • the fourth sub-connector may be connected to the third conductive pattern 323.
  • the electrical signal generator 360 may determine on or off of at least one of the sub connection units. In other words, the electrical signal generator 360 may determine on or off of at least one of the electrical signals provided to each of the sub-connectors.
  • the electrical signal generator 360 may include a pair of sub-products of the first electrical signal or the first conductive pattern 321 that are involved in the operation of the first sub-electrode portion of the pair of sub-electrode portions of the electrode portion 340.
  • the third electrical signal related to the operation of the conductive pattern 323 or the second drug unit 333 may be turned on.
  • the electrical signal generator 360 may periodically or sequentially determine at least one of On or Off of the sub connection units. In addition, the electrical signal generator 360 may determine to alternate on or off of at least one of the sub-connectors. According to another embodiment of the present application, the electrical signal generator 360 is based on (On) or (Off) of any one of the sub-connector based on (On) or off (Off) of the other one of the sub-connector. Can be determined. An example of this is replaced with the example described above with reference to FIGS. 3 and 4. In addition, the description related to the electrical signal generator 360 may be applied to all of the electrical signal generators described with reference to FIGS. 1 to 6.
  • FIG. 8 is a view showing a patch type electrical stimulation device according to another embodiment of the present application.
  • a patch type electrical stimulation device according to another embodiment of the present disclosure will be described with reference to FIG. 8.
  • the descriptions thereof may be applied mutatis mutandis as described above with reference to FIGS. 1 to 6.
  • Patch type electrical stimulation device 400 includes a body portion 410, the first conductive pattern 421, the second conductive pattern 422, the electrode portion 440 and the connecting portion 450 can do.
  • the drug unit 430 may include a first drug unit 431 and a second drug unit 432.
  • the first conductive pattern 421 may be formed in the first region of the body portion 410.
  • the first conductive pattern 421 may transfer the first electrical signal generated by the electrical signal generator (not shown) to the electrode unit 440.
  • the first conductive pattern 421 may include a pair of sub conductive patterns. The description of the first conductive pattern 421 and the second conductive pattern 422 is replaced with the description of the various conductive patterns described above with reference to FIGS. 1 to 6.
  • the second conductive pattern 422 may be formed between the second region of the body portion 410 and the first drug portion 321.
  • the second conductive pattern 422 may transmit a second electric signal generated by an electric signal generator (not shown).
  • the second conductive pattern 422 may transmit the second electrical signal to the first drug part 431.
  • the second electrical signal may cause the drug contained in the first drug unit 431 to be released by iontophoresis.
  • the electrode unit 440 may generate an electrical stimulus based on the first electrical signal.
  • the electrode unit 440 may include an adhesive layer for adhesion (or contact) with the skin of an object (eg, a body) on one surface.
  • the adhesive layer may be formed in a gel form, an example of the gel may be a hydrogel.
  • the description of the electrode unit 440 is replaced with the description of the various electrode units described with reference to FIGS. 1 to 6.
  • the first drug unit 431 may include the first drug
  • the second drug unit 432 may include the second drug.
  • the first drug part 431 may be formed to be stacked on the second conductive pattern 422.
  • the second drug part 432 may be formed in the third region of the body part 410.
  • the second drug part 432 may be formed to be stacked on the third area of the body part 410.
  • the first drug portion 431 may be an active drug portion, and the second drug portion 432 may be a passive drug portion.
  • the first drug part 431 may include a first drug released by iontophoresis, and the second drug part 432 may include a first drug that is naturally released.
  • the first conductive pattern 321, the second conductive pattern 322, the electrode portion 440, the first drug portion 431 and the second drug portion 432 described above. May be formed.
  • Such a body portion 410 may be formed in a patch shape, the shape, thickness, material, etc. may be variously determined according to the portion of the object to be applied or bonded.
  • the details of the patch type electrical stimulation apparatus 400 of FIG. 8 may be easily inferred by those skilled in the art from the above description of the patch type electrical stimulation apparatus of FIGS. 1 to 7, and thus description thereof will be omitted. .
  • the patch type electrical stimulation device may include a plurality of electrode portions and a plurality of drug portions.
  • at least two of the plurality of electrode portions and the plurality of drug portions may be physically or electrically separated from each other.
  • the plurality of electrode portions and the plurality of drug portions may be formed to be adjacent to each other or side by side at intervals.
  • the first drug unit may be formed adjacent to the second drug unit at intervals.
  • the first drug unit may be formed in parallel with the second drug unit at intervals.
  • the first drug part and the second drug part may be disposed adjacent to each other, as if in a lattice pattern.
  • the first drug part and the second drug part may be arranged next to each other or side by side, like a stripe.
  • Such an example may be applied between the electrode portion and the drug portion, and may be applied between the passive drug portion and the active drug portion.
  • one row of passive drug portions containing a first drug and the other row of active drug portions containing a second drug are disposed, and this arrangement may be repeated within the drug portion.
  • the conductive part is formed between the electrode part and the active drug part and the electrode part (or the active drug part), while the passive drug part may be formed by directly contacting the body part and the passive drug part.
  • the electrode unit may include a plurality of sub electrode units.
  • the drug unit, the first drug unit and the second drug unit of the present application may each include a plurality of sub drug units.
  • at least two of the plurality of sub electrode portions and the plurality of sub drug portions may be physically or electrically separated from each other.
  • the plurality of sub-electrode portions and the plurality of sub-drug portions may be formed to be adjacent to each other or side by side at intervals.
  • the first sub drug part included in the drug part may be formed adjacent to the second sub drug part at intervals.
  • the first sub drug part included in the drug part may be formed in parallel with the second sub drug part at intervals.
  • the first sub drug part and the second sub drug part may be disposed adjacent to each other, like a lattice pattern, as in reference numeral (a).
  • the first sub drug part and the second sub drug part may be arranged next to each other or side by side like a stripe.
  • Such an example may be applied between the sub-electrode portion and the sub-drug portion, and may be applied between the sub-passive drug portion and the sub-active drug portion.
  • one row is arranged with a sub-passive drug part containing the first drug and the other is with a sub-active drug part containing the second drug, such arrangement being within the drug part. Can be repeated.
  • the conductive pattern is formed between the body portion and the sub-electrode portion (or sub-active drug portion) while the sub-electrode portion and the sub-active drug portion are formed by directly contacting the body portion and the sub-passive drug portion.
  • the sub-passive drug portion may naturally diffuse the drug like the passive drug portion, while the sub-active drug portion may diffuse the drug by iontophoresis like the active drug portion.
  • FIG. 10 is an operation flowchart of a control method of a patch type electrical stimulation apparatus according to an embodiment of the present application.
  • the control method of the patch type electrical stimulation apparatus according to the embodiment shown in FIG. 10 is provided through the patch type electrical stimulation apparatus 200, the patch type electrical stimulation apparatus 300, and the patch type electrical stimulation apparatus 400 described with reference to FIGS. 3 to 9. Steps that are processed in time series. Therefore, although omitted below, the above descriptions regarding the patch type electrical stimulation apparatus 200, the patch type electrical stimulation apparatus 300, and the patch type electrical stimulation apparatus 400 described with reference to FIGS. 3 to 9 will be described with reference to FIG. 10. It can also be applied to the control method of the patch type electrical stimulation apparatus according to the embodiment shown in.
  • the electrical signal generator may generate a first electrical signal corresponding to the electrode of the patch type electrical stimulation device.
  • the first electrical signal may be transmitted to the electrode unit through the first conductive pattern formed in the first region of the body portion of the patch type electrical stimulation device.
  • a second electrical signal corresponding to the drug unit of the patch type electrical stimulation device may be generated.
  • the second electrical signal may be transmitted to the drug unit through the second conductive pattern formed in the second area of the body of the patch type electrical stimulation device.
  • Computer readable media can be any available media that can be accessed by a computer and includes both volatile and nonvolatile media, removable and non-removable media.
  • Computer readable media may include both computer storage media and communication media.
  • Computer storage media includes both volatile and nonvolatile, removable and non-removable media implemented in any method or technology for storage of information such as computer readable instructions, data structures, program modules or other data.
  • Communication media typically includes computer readable instructions, data structures, program modules, or other data in a modulated data signal such as a carrier wave, or other transmission mechanism, and includes any information delivery media.
  • the present invention may also be implemented in the form of a computer program stored in a recording medium for executing the above-described control method.
  • the present disclosure may be implemented in the form of an application stored in a recording medium included in a mobile device such as a smartphone, a tablet, or the like, or a server held by an app store providing an application to the mobile device.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)

Abstract

L'invention concerne un appareil de stimulation électrique de type timbre. L'appareil de stimulation électrique de type timbre peut comprendre : une partie corps ; un motif conducteur qui est formé dans une première zone de la partie corps pour transmettre, à une partie électrode, un signal électrique généré par une partie de génération de signal électrique ; une partie électrode qui génère une stimulation électrique sur la base du signal électrique ; et une partie médicament qui est formée dans une seconde zone de la partie corps et comprend un médicament.
PCT/KR2016/011350 2015-11-23 2016-10-11 Appareil de stimulation électrique de type timbre apte à l'administration de médicament et son procédé de commande WO2017090886A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020150164194A KR101915697B1 (ko) 2015-11-23 2015-11-23 약물전달이 가능한 패치형 전기자극 장치 및 그 제어 방법
KR10-2015-0164194 2015-11-23

Publications (1)

Publication Number Publication Date
WO2017090886A1 true WO2017090886A1 (fr) 2017-06-01

Family

ID=58763392

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2016/011350 WO2017090886A1 (fr) 2015-11-23 2016-10-11 Appareil de stimulation électrique de type timbre apte à l'administration de médicament et son procédé de commande

Country Status (2)

Country Link
KR (1) KR101915697B1 (fr)
WO (1) WO2017090886A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108837303A (zh) * 2018-06-28 2018-11-20 成都三乙医疗科技有限公司 一种消肿止痛的电极治疗片

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456012A (en) * 1982-02-22 1984-06-26 Medtronic, Inc. Iontophoretic and electrical tissue stimulation device
US20040138712A1 (en) * 2002-11-29 2004-07-15 Dov Tamarkin Combination stimulating and exothermic heating device and method of use thereof
KR20080044259A (ko) * 2005-08-05 2008-05-20 티티아이 엘뷰 가부시키가이샤 이온토포레시스 장치
US20090048556A1 (en) * 2007-08-17 2009-02-19 Isis Biopolymer Llc Iontophoretic drug delivery system
KR101139956B1 (ko) * 2012-01-12 2012-04-30 원창연 기미?주름?미백 관리를 위한 초미세 진동 마사지기

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007504882A (ja) 2003-09-10 2007-03-08 パワー ペーパー リミティド 使い捨て電気包帯
US20130281914A1 (en) * 2010-12-28 2013-10-24 Terumo Kabushiki Kaisha Transdermal drug administration device
US20150246215A1 (en) * 2012-12-25 2015-09-03 Teikoku Seiyaku Co., Ltd. Iontophoresis patch

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456012A (en) * 1982-02-22 1984-06-26 Medtronic, Inc. Iontophoretic and electrical tissue stimulation device
US20040138712A1 (en) * 2002-11-29 2004-07-15 Dov Tamarkin Combination stimulating and exothermic heating device and method of use thereof
KR20080044259A (ko) * 2005-08-05 2008-05-20 티티아이 엘뷰 가부시키가이샤 이온토포레시스 장치
US20090048556A1 (en) * 2007-08-17 2009-02-19 Isis Biopolymer Llc Iontophoretic drug delivery system
KR101139956B1 (ko) * 2012-01-12 2012-04-30 원창연 기미?주름?미백 관리를 위한 초미세 진동 마사지기

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108837303A (zh) * 2018-06-28 2018-11-20 成都三乙医疗科技有限公司 一种消肿止痛的电极治疗片

Also Published As

Publication number Publication date
KR20170059785A (ko) 2017-05-31
KR101915697B1 (ko) 2018-11-06

Similar Documents

Publication Publication Date Title
WO2015199327A1 (fr) Appareil de neurostimulation électrique transcutanée (tens)
WO2016017954A1 (fr) Dispositif de stimulation électrique
WO2013027954A2 (fr) Dispositif de massage facial
WO2019168227A1 (fr) Ensemble masque facial électrique
WO2020059982A1 (fr) Stimulateur électrique d'exercice musculaire
WO2017095198A1 (fr) Dispositif d'implant de corps humain
WO2018208009A1 (fr) Oculaire fonctionnel avec structure d'application de stimulation électrique
WO2021080278A1 (fr) Dispositif de massage ionique pour soins de la peau
WO2022250318A1 (fr) Gant de massage basse fréquence
WO2016175519A1 (fr) Dispositif de stimulation électrique
WO2017090886A1 (fr) Appareil de stimulation électrique de type timbre apte à l'administration de médicament et son procédé de commande
WO2016175523A1 (fr) Dispositif de stimulation électrique et unité adhésive remplaçable
WO2018038541A1 (fr) Connecteur de patch pour exercice de la peau et soins de la peau
WO2019194591A1 (fr) Dispositif à basse fréquence variable pour soulager les douleurs musculaires et articulaires
WO2011093540A1 (fr) Appareil de type serre-tête pour empêcher la somnolence
WO2019074138A1 (fr) Dispositif iontophorétique d'injection cutanée avec substance médicale ou cosmétique
JP7199276B2 (ja) 筋肉電気刺激装置
KR101854305B1 (ko) 전기 자극용 기능성 의복
WO2017095173A1 (fr) Unité de test de mise à la terre
WO2024058313A1 (fr) Système de dispositif d'exercice ems comprenant un capteur
WO2018225976A1 (fr) Dispositif intelligent doté d'une fonction de fourniture d'onde
DK2741811T3 (en) SYMPTOM HANDLING SYSTEM
WO2017222190A1 (fr) Soins de la peau sous forme de masque comportant une électrode en forme de motifs agencés.
KR101995441B1 (ko) 약물전달이 가능한 패치형 전기자극 장치 및 그 제어 방법
WO2020175714A1 (fr) Dispositif de thérapie électromagnétique de type ceinture

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16868785

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 16868785

Country of ref document: EP

Kind code of ref document: A1