WO2017075841A1 - Procédé, appareil et dispositif non invasifs de mesure de pression artérielle - Google Patents

Procédé, appareil et dispositif non invasifs de mesure de pression artérielle Download PDF

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Publication number
WO2017075841A1
WO2017075841A1 PCT/CN2015/094162 CN2015094162W WO2017075841A1 WO 2017075841 A1 WO2017075841 A1 WO 2017075841A1 CN 2015094162 W CN2015094162 W CN 2015094162W WO 2017075841 A1 WO2017075841 A1 WO 2017075841A1
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WO
WIPO (PCT)
Prior art keywords
blood pressure
measured
real time
invasive
detecting device
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PCT/CN2015/094162
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English (en)
Chinese (zh)
Inventor
李久朝
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深圳市维亿魄科技有限公司
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Publication of WO2017075841A1 publication Critical patent/WO2017075841A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/0225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds

Definitions

  • the present invention relates to the field of smart wearable devices, and in particular, to a non-invasive blood pressure detecting method, device and device.
  • the non-invasive blood pressure detection method uses an oscillation method based on the cuff method pulse wave.
  • the non-invasive detection methods of human blood pressure mainly include the Korotkoff sound auscultation method and the proportional coefficient method of the cuff oscillation wave.
  • the Korotkoff method is an experienced medical staff using a stethoscope, a mercury pressure gauge and a cuff, and a charging/discharging airbag.
  • the stethoscope By attaching the cuff to the appropriate position of the subject's upper arm, the stethoscope is placed close to the radial artery to charge/displace the balloon.
  • the cuff inflation increases the pressure until the blood flow in the arm is blocked, and then the cuff pressure is gradually reduced by the charge/discharge balloon to restore the blood flow of the arm.
  • the arterial blood flow pulsation of the arm produces a small to large, and then Large to small changes in Korotkoff sound, and the changes in Korotkoff sound can be heard with a stethoscope and a mercury pressure gauge to determine systolic and diastolic blood pressure.
  • the basic process is very similar to the auscultation method. It is also boosted by the cuff inflation to block the blood flow of the arm, and then gradually lower the cuff.
  • the calculation method is Detecting the pressure pulse wave generated by the arterial blood flow pulsation during the deflation process and the corresponding cuff pressure generated in the cuff, can detect a set of amplitude pulse waves from small to large, and then from small to large From the large to small cuff pressure, the cuff pressure corresponding to the maximum value of the pressure pulse wave is the average pressure, and the systolic blood pressure and the diastolic blood pressure are derived from the amplitude coefficient of the pressure pulse wave of the empirical value.
  • a non-invasive blood pressure detecting method includes:
  • the non-invasive blood pressure detecting device measures the blood pressure by using a pressurized blood pressure measuring method and sets it as a reference blood pressure;
  • the non-invasive blood pressure detecting device uses a photoelectric blood pressure measurement method to measure blood pressure in real time;
  • the blood pressure measured in real time is abnormal
  • the blood pressure measured by the real-time measurement is verified by a pressurized blood pressure measurement method
  • the reference blood pressure is calibrated and updated.
  • a non-invasive blood pressure detecting device includes:
  • a component for setting a non-invasive blood pressure detecting device to a zero return mode or a continuous wear mode a component for setting a non-invasive blood pressure detecting device to a zero return mode or a continuous wear mode
  • a non-invasive blood pressure detecting device has a return-to-zero mode and a continuous wearing mode and includes a microprocessor and a pneumatic cuff, a motion sensor processing module, and a photoelectric sensor respectively connected to the microprocessor;
  • the motion sensor processing module acquires motion data of the user, and when the user determines that the user is in a static state according to the motion data, the inflatable cuff begins to inflate, and the non-invasive blood pressure detecting device enters a pressurized blood pressure measurement. Way, measuring blood pressure and recording blood pressure value, and setting the measured blood pressure value to the reference blood pressure;
  • the motion sensor processing module acquires motion data of the user, and determines that the user is in a static state according to the motion data, and enters a photoelectric blood pressure measurement mode, wherein the photoelectric sensor measures blood pressure in real time and records a blood pressure value;
  • the microprocessor is configured to: when the blood pressure measured in real time exceeds a normal blood pressure range, check whether the blood pressure measured in real time is abnormal according to the reference blood pressure; and when it is determined that the blood pressure measured in real time is abnormal, use a pressurized blood pressure
  • the measurement mode verifies the real-time measured blood pressure; when it is determined that the real-time measured blood pressure is non-abnormal, the reference blood pressure is calibrated and updated.
  • the above non-invasive blood pressure detecting method adopts two different blood pressure measuring methods to accurately measure blood pressure in real time, and the method combines the advantages of the accuracy of the conventional pressurized blood pressure measuring method with the advantages of the non-invasive and non-inductive real-time measurement of the photoelectric detecting, and non-invasive through photoelectricity.
  • the non-inductive detection of the change trend of blood pressure to control the traditional pressurized blood pressure measurement can not only ensure the accuracy of blood pressure measurement, but also minimize the discomfort caused by frequent pressurization, and can also monitor the change of blood pressure in real time.
  • the non-invasive blood pressure detection method is compared with the photoelectric blood pressure measurement method to ensure the accuracy of the blood pressure measurement value, and the continuous measurement of blood pressure in real time is compared with the pressurized blood pressure measurement, which greatly improves the comfort of the pressurized blood pressure measurement.
  • the non-invasive blood pressure detecting device realizes the combination of the pressurized and photoelectric methods, and complements the length, ensures the accuracy of the blood pressure value and meets the needs of real-time monitoring, and minimizes the pressure-induced blood pressure measurement. Discomfort.
  • FIG. 1 is a schematic view of a frame of a non-invasive blood pressure detecting device according to an embodiment
  • FIG. 2 is a flow chart of a non-invasive blood pressure detecting method according to an embodiment.
  • a non-invasive blood pressure detecting device includes an inflatable cuff 101, a motion sensor processing module 102, a photoelectric sensor 103, a charge and discharge command module 104, a pressure pulse wave signal control module 105, a pressure feedback module 106, and a charging and discharging device.
  • the inflatable cuff 101 is in communication with the charge and discharge command module 104, the pressure pulse wave signal control module 105, the pressure feedback module 106, and the charge and discharge gas non-polarity control module 107, respectively.
  • the microprocessor 110 is also in communication with the charge and discharge command module 104, the pressure pulse wave signal control module 105, the pressure feedback module 106, and the charge and discharge gas non-polarity control module 107.
  • the inflatable cuff 101 is configured to measure blood pressure using a pressurized blood pressure measurement method; the charge and discharge command module 104 is configured to control the charge and discharge of the inflatable cuff 101; the pressure pulse wave signal control module 105 is configured to collect and release a pulse wave in the gas process; the pressure feedback module 106 is configured to feed back pressure information of the inflatable cuff 101 to the microprocessor 110; the charge and discharge airless control module 107 is configured to control the charge and discharge speed of the inflatable cuff 101 .
  • the motion sensor processing module 102 is in communication with the microprocessor 110 and is configured to acquire motion data of the user.
  • the photosensors 103 are communicatively coupled to the photodetection module 108 and the optoelectronic signal processing module 109, respectively.
  • the microprocessor 110 is also communicatively coupled to the photodetection module 108 and the optoelectronic signal processing module 109, respectively.
  • the photosensor 110 is configured to measure blood pressure using a photo-electric blood pressure measurement method
  • the photo-detection module 108 is configured to detect change information of the reflected signal to monitor a pulse beat condition
  • the photo-electric signal processing module 109 is configured to pulse the human body
  • the acquisition data of the wave signal is transmitted to the microprocessor 110.
  • the photodetection module 108 and the optoelectronic signal processing module 109 can be integrated with the photosensor 110.
  • the non-invasive blood pressure detecting device further includes a display 111 and a communication interface 112 for communicating with the server 113.
  • Display 111 is electrically coupled to microprocessor 110 and is configured to display the value of the measured blood pressure.
  • Server 113 is coupled to microprocessor 113 via communication interface 112, which is configured to receive and display blood pressure data transmitted from communication interface 112 or for further data processing.
  • the non-invasive blood pressure detecting device can measure blood pressure accurately in real time through two different blood pressure measuring methods.
  • the non-invasive blood pressure detecting device combines the advantages of the accuracy of the conventional pressurized blood pressure measuring method with the advantages of the non-invasive and non-inductive real-time measurement of the photoelectric detecting, and controls the conventional pressurized blood pressure measurement by detecting the change trend of the blood pressure by the non-invasive photoelectric sense. It can ensure the accuracy of blood pressure measurement and minimize the discomfort caused by frequent pressure, and also monitor the changes of blood pressure in real time.
  • the non-invasive blood pressure detecting method of an embodiment includes the following steps:
  • step S210 detecting whether the inflatable cuff is used for the first time wearing, if yes, proceeding to step S230, the non-invasive blood pressure detecting device first enters the return to zero mode, and then switching from the return to zero mode to the continuous wearing mode to step S240; if not, then entering In step S220, it is determined whether the unworn interval of the inflatable cuff exceeds a preset duration. If yes, the process proceeds to step S230, the non-invasive blood pressure detecting device first enters the return to zero mode, and then switches from the zero return mode to the continuous wear mode to proceed to step S240. Otherwise, the process proceeds to step S240, and the continuous wear mode is directly entered.
  • the non-invasive blood pressure detecting device uses the pressurized blood pressure measuring method to obtain the reference blood pressure; in the continuous wearing mode, the non-invasive blood pressure detecting device uses the photoelectric blood pressure measuring method to measure the blood pressure in real time, and the average blood pressure is measured continuously for N times. The value is compared with the reference blood pressure, and the comparison proceeds to step S250. If the absolute value of the difference between the average value and the reference blood pressure is greater than or equal to the first set value, the inflatable cuff begins to be inflated for pressurized blood pressure measurement, and the comparison is performed.
  • the difference between the blood pressure value of the secondary pressure blood pressure measurement and the reference blood pressure if the difference is greater than the second set value, an alarm is given and the reference blood pressure is updated, and the blood pressure value of the pressurized blood pressure measurement is used as the reference blood pressure. . Otherwise, the reference blood pressure is updated, and the blood pressure value of the current pressurized blood pressure measurement is used as the reference blood pressure, but no alarm is given; wherein N is an integer and N ⁇ 2.
  • the first set value is 20-30 mmHg, preferably 25 mmHg; the second set value is 20-30 mmHg, preferably 25 mmHg.
  • the above parameters can also be corrected according to the actual application.
  • using the pressurized blood pressure measurement method to obtain the reference blood pressure value in the return-to-zero mode includes the following steps:
  • the motion sensor processing module 102 acquires the motion data of the user, and when it is determined that the user is in a static state according to the motion data, the inflatable cuff 101 starts to inflate, and the non-invasive blood pressure detecting device enters the pressurized blood pressure measurement mode, measures the blood pressure, and records the blood pressure value. At the same time, the measured blood pressure value is used as the reference blood pressure.
  • the pressurized blood pressure measuring method is to measure blood pressure by using an oscillating method, and the specific steps are as follows: firstly, the blood flow of the blood vessel is blocked by inflating and pressing the inflatable cuff 101, and then the deflation is gradually performed, and the pulse during the deflation process is recorded. The wave is subjected to interpolation fitting analysis processing on the pulse wave during deflation, and the blood pressure value corresponding to the waveform of the highest amplitude is recorded as the average pressure, and the systolic pressure and the diastolic pressure are calculated according to the proportional coefficient.
  • the oscillating pulse wave is recovered according to an algorithm, and the envelope is obtained by nonlinear fitting, and data processing is performed to obtain a pulse wave change trend, and an average pressure is calculated, and systolic blood pressure and diastolic blood pressure are further obtained, and passed.
  • the photoelectric sensor nonlinearly fits the waveform of the pulse wave to obtain a trend of blood pressure change.
  • the non-invasive blood pressure detecting device uses the photoelectric blood pressure measurement method to measure blood pressure in real time in the continuous wearing mode, and includes the following steps:
  • the motion sensor processing module 102 of the non-invasive blood pressure detecting device acquires the motion data of the user, and after the data processing determines that the user is in a stationary state according to the motion data, the photoelectric sensor of the non-invasive blood pressure detecting device is turned on, enters the photoelectric blood pressure measuring mode, and measures the blood pressure. And record the blood pressure value.
  • the photoelectric blood pressure measurement method is specifically: the photoelectric sensor monitors the pulse beat according to the change of the received reflected signal, and transmits the collected data of the human pulse wave signal to the microprocessor, and the microprocessor according to the pre- Let the algorithm analyze the change of the pulse wave waveform to get the trend of blood pressure.
  • the photoelectric blood pressure measurement method is based on the absorption of red light by blood, and the sensor monitors the pulse beat by receiving a change in the reflected signal.
  • the photoelectric pulse sensor collects and transmits the pulse wave signal of the human body to the microprocessor, and the microprocessor can determine the change trend of the blood pressure according to the analysis of the change of the pulse wave waveform by the algorithm.
  • the photoelectric sensor comprises a green light sensor and a near infrared sensor, and determining whether the unworn interval of the inflatable cuff exceeds a preset duration comprises the following steps:
  • the user's wearing posture is judged according to the motion data obtained by the motion sensor processing module, if the user's If the wearing posture is a preset reasonable wearing posture, the condition one is satisfied.
  • the reasonable wearing posture may be a preset motion data range.
  • condition one and condition two When both condition one and condition two are satisfied, it is judged that the user is wearing the inflatable cuff, otherwise the user does not wear the inflatable cuff and records the time when the inflatable cuff is not worn.
  • the preset duration can be 12 hours (this time can be properly corrected), and if it is not worn for more than 12 hours, it will enter the zero return mode.
  • the set time is preferably 30 s, and the set time can be appropriately corrected.
  • the pneumatic cuff pressure signal measured by the pressure feedback module is transmitted to the microprocessor, and the microprocessor infinitely controls the charge and discharge velocity of the inflatable cuff according to the inflatable cuff pressure signal.
  • the microprocessor controls the charging and discharging gas speed to realize the stepless control, and can accurately control the speed of the charging and discharging gas and the blocking pressure value of the inflation, and the entire measuring time is also reduced to some extent.
  • the inflatable cuff can be integrated with the strap, and the blood pressure of the wrist is measured by a pressurized blood pressure measurement.
  • the non-invasive blood pressure detecting device is a wearable device, and the inflatable cuff and the strap are combined, and the pressurized blood pressure measures the blood pressure of the wrist of the human body.
  • the reference blood pressure value is obtained by the pressurized blood pressure measurement method, and the matching mode is switched, and the photoelectric blood pressure measurement method tracks the blood pressure trend in real time. Once the blood pressure value is abnormal, the pressurized blood pressure measurement method is started to measure the blood pressure to determine the blood pressure. Whether the value reaches the warning level.
  • the non-invasive blood pressure detecting method and the non-invasive blood pressure detecting device of the above embodiments use two different blood pressure measuring methods to accurately measure blood pressure in real time, and the method has the advantages of the accuracy of the conventional pressurized blood pressure measuring method and the non-invasive feeling of photoelectric detection.
  • the advantages of real-time measurement combine to control the traditional pressurized blood pressure measurement by photoelectric non-invasive non-inductive detection of blood pressure changes, which can ensure the accuracy of blood pressure measurement and minimize the discomfort caused by frequent pressurization. Real-time monitoring of changes in blood pressure.
  • the non-invasive blood pressure detection method is compared with the photoelectric blood pressure measurement method to ensure the accuracy of the blood pressure measurement value, and the continuous measurement of blood pressure in real time is compared with the pressurized blood pressure measurement, which greatly improves the comfort of the pressurized blood pressure measurement.
  • the non-invasive blood pressure detecting device realizes the combination of the pressurized and photoelectric methods, and complements the length, ensures the accuracy of the blood pressure value and meets the needs of real-time monitoring, and minimizes the pressure-induced blood pressure measurement. Discomfort.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

L'invention concerne un procédé non invasif de mesure de pression artérielle, comprenant les étapes suivantes : régler un dispositif de mesure de pression artérielle non invasif à un mode de remise à zéro ou un mode de port continu ; dans le mode de remise à zéro, activer le dispositif de mesure de pression artérielle non-invasif pour mesurer une pression artérielle au moyen d'une approche de mesure de pression artérielle de type pressurisation et définir la pression artérielle mesurée comme pression artérielle de référence ; dans le mode de port continu, activer le dispositif de mesure de pression artérielle non-invasif pour mesurer la pression artérielle en temps réel au moyen d'une approche de mesure de pression artérielle photoélectrique ; déterminer si la pression artérielle mesurée en temps réel est anormale par rapport à la pression artérielle de référence lorsque la pression artérielle mesurée en temps réel dépasse une plage de pression artérielle normale ; vérifier, au moyen de l'approche de mesure de pression artérielle de type pressurisation, lorsqu'il est déterminé que la pression artérielle mesurée en temps réel est anormale, la pression artérielle mesurée en temps réel ; et étalonner et mettre à jour la pression artérielle de référence lorsqu'il est déterminé que la pression artérielle mesurée en temps réel n'est pas anormale.
PCT/CN2015/094162 2015-11-03 2015-11-10 Procédé, appareil et dispositif non invasifs de mesure de pression artérielle WO2017075841A1 (fr)

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CN201510746149.9A CN106618540B (zh) 2015-11-03 2015-11-03 无创血压检测方法及无创血压检测装置
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CN109009044A (zh) * 2018-08-15 2018-12-18 合肥博谐电子科技有限公司 一种新型脉搏波获取装置
CN112914531A (zh) * 2021-01-19 2021-06-08 深圳市杰纳瑞医疗仪器股份有限公司 确定血压包络波的方法、电子设备及存储介质
CN114259394A (zh) * 2021-12-13 2022-04-01 重庆邮电大学 一种具有综合康复训练策略的预适应训练系统

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CN108577820A (zh) * 2018-03-26 2018-09-28 何史林 一种实时血压快速预警系统及其方法
CN112022128A (zh) * 2019-06-04 2020-12-04 深圳市理邦精密仪器股份有限公司 医疗设备及其基于ptt的无创血压测量方法与装置
CN113017583A (zh) * 2019-12-24 2021-06-25 华为技术有限公司 血压测量方法及装置
CN111990980B (zh) * 2020-08-17 2023-07-07 中孚医疗（深圳）有限公司 血压测量方法及血压测量设备
CN113662520B (zh) * 2021-08-26 2022-10-14 电子科技大学 一种基于不确定性量化策略的可穿戴连续血压测量系统

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CN109009044A (zh) * 2018-08-15 2018-12-18 合肥博谐电子科技有限公司 一种新型脉搏波获取装置
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CN112914531A (zh) * 2021-01-19 2021-06-08 深圳市杰纳瑞医疗仪器股份有限公司 确定血压包络波的方法、电子设备及存储介质
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CN114259394A (zh) * 2021-12-13 2022-04-01 重庆邮电大学 一种具有综合康复训练策略的预适应训练系统
CN114259394B (zh) * 2021-12-13 2024-04-09 重庆邮电大学 一种具有综合康复训练策略的预适应训练系统

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