WO2017075314A1 - Aseptic aerosol misting device - Google Patents
Aseptic aerosol misting device Download PDFInfo
- Publication number
- WO2017075314A1 WO2017075314A1 PCT/US2016/059265 US2016059265W WO2017075314A1 WO 2017075314 A1 WO2017075314 A1 WO 2017075314A1 US 2016059265 W US2016059265 W US 2016059265W WO 2017075314 A1 WO2017075314 A1 WO 2017075314A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nozzle
- liquid
- horn
- distal end
- misting device
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0623—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers coupled with a vibrating horn
- B05B17/063—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers coupled with a vibrating horn having an internal channel for supplying the liquid or other fluent material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0063—Storages for pre-packed dosages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0661—Transducer materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0669—Excitation frequencies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
Definitions
- the present invention relates to an aseptic misting device employing a permanent sonic generator and a replaceable liquid reservoir and nozzle.
- Spray and/or misting devices are often used to delivery cosmetic and general health care liquids.
- Low cost systems employ droppers and/or squeeze bottles with some form of nozzle through which the liquid is forced to provide a relatively uncontrolled dosage and droplet size.
- Expensive systems may employ metering pumps and/or expensive aerosol forming components.
- Hseih et al. US 7992800 and Hseih et al. US Pub. Pat. Appn. No. 20120318260 disclose nebulizers driven by piezo-electric and/or magnetic drives to generate an aerosol mist.
- Esaki et al. US8286629 disclose ultrasonic liquid atomizing devices.
- a handheld misting device has a housing having a dispensing window is arranged and configured to contain a sonic generator, a power source coupled to the sonic generator, at least one reservoir containing a liquid, and a conduit extending from the at least one reservoir to a nozzle removably coupled to the sonic generator.
- the sonic generator includes a converter and an elongate horn having a proximal end coupled to the converter and a distal end, and the nozzle is removably coupled to the distal end of the horn.
- the device delivers the liquid through a delivery opening formed in the nozzle, and activating the sonic generator energizes the liquid in the nozzle to generate an aerosol plume that is delivered through the dispensing window.
- Fig. 1 is a perspective view of a handheld aseptic misting device according to one embodiment of the invention.
- Fig. 2 is a side view of the handheld aseptic misting device of Fig. 1 with the housing removed to show the interior components.
- Fig. 3 is a side view of the disposable cartridge of the handheld aseptic misting device of Figs. 1 and 2 with the housing removed to show the interior components.
- Figs. 4A-C are perspective views of various nozzle and receptacle combinations useful in the handheld aseptic misting device of Fig. 1 .
- Fig. 5 is a detailed side view of the distal end of the sonic horn having surface features to prevent undesired misting of liquids that may migrate to the distal end of the horn.
- Fig. 6 is a perspective view of elements of a handheld aseptic misting device according to a second embodiment of the invention
- Fig. 7 is a schematic cross-section of a handheld aseptic misting device according to a third embodiment of the invention.
- Fig. 8 is a schematic cross-section of a handheld aseptic misting device according to a fourth embodiment of the invention. Detailed Description of the Preferred Embodiments
- the present invention relates to a handheld sonic misting device that is more economical than conventional sonic misting devices, because the relatively expensive sonic generator and horn are isolated from liquids dispensed by the misting device. Thus, the misting device can be replenished with liquids without significant build-up of liquids on the horn.
- a conduit delivers the liquid to be dispensed to the tip of the horn in a system arranged and configured to direct the liquid away from the horn, such that the horn is not contaminated by the liquid and further, subsequent liquids dispensed from the device are not contaminated by previously dispensed liquids.
- the handheld misting device 100 (including a sonic generator 200, a liquid delivery system 300, and an electric power and control system 400) useful to form an aerosol comprising liquid droplets (referred to herein as a "mist” or “plume”) is contained within a housing 500.
- the sonic generator 200 includes a converter 202 and an elongate horn 204 having a proximal end 206 coupled to the converter 202 and a distal end 208, opposite thereof, visible through an open dispensing window 502 in the housing 500.
- the converter 202 is coupled to the electric power and control system 400 through electrical connections, such as wires (not shown).
- the liquid delivery system 300 includes a collapsible reservoir 302, a conduit 304, a nozzle 306 having at least one delivery opening 308, and a linear motor 310.
- the piston 312 of the linear motor 310 contacts the lower surface 314 of the reservoir 302 to force liquid out of reservoir and into conduit 304.
- the linear motor 310 is also coupled to the electric power and control system 400 through appropriate electrical connections, such as wires (not shown).
- the conduit 304 conducts liquid from the collapsible reservoir 302 to the nozzle 306, and the nozzle 306 is physically coupled to the distal end 208 of the elongate horn 204.
- the nozzle 306 is arranged and configured to dispense liquid from the collapsible reservoir 302 to the atmosphere through the dispensing window 502 in the housing 500.
- the nozzle 306 is protected during storage by closing the dispensing window 502 with a cover 504.
- the liquid delivery system 300 described above includes a collapsible reservoir 302 and a linear motor 310, one of ordinary skill in the art will recognize that other systems may be used.
- the collapsible reservoir and linear motor provide one solution to the problem of delivering controlled volumes of liquid from the reservoir.
- Alternative systems may also be used.
- the same functionality as the reservoir and pump may be delivered via one or more of the following: pipette, syringe, squeezable bag, pressure actuated reservoir, and even gravity feed.
- the housing 500 includes a first, electromechanical section 506 (shown in Fig. 2) that houses components including the sonic generator 200, the electric power and control system 400, and the linear motor 310 of the liquid delivery system 300, and a second, liquid section 508 (shown in Fig. 3) that houses the collapsible reservoir 302, conduit 304, and nozzle 306 having at least one delivery opening (shown as 308a, 308b, 308c in Figs. 4A-4C).
- the liquid section 508 is a separate, removable section that can be securely attached to the electromechanical section 506.
- the liquid section 508 may be an openable compartment in the housing 500 that is arranged and configured to receive replacement collapsible reservoir 302, conduit 304, and nozzle 306.
- the electric power and control system 400 includes a power source, such as a rechargeable battery 402, that is electrically connected to an electrical charging port 404 disposed in the housing 500.
- the electric power and control system 400 also includes an on/off switch 406 and an activation switch 408, both disposed on the housing 500, and one or more control boards 410.
- the power source is preferably replaceable and/or rechargeable and may include devices such as a capacitor or, more preferably, a battery.
- the power source 402 is a rechargeable battery including, without limitation, lithium-based cells, including lithium polymer batteries.
- an internal power source is a lithium polymer cell providing a voltage of about 3.7 V that has a capacity of at least about 200 milliamp hours (mAh).
- nozzle shown as 306a, 306b, 306c in Figs. 4A-4C
- distal end 208 of the elongate horn 204 is shown greater detail in Figs. 4A-4C.
- the nozzle 306 is securely fitted into a receptacle 210 formed in the distal end 208 of the elongate horn 204. This substantial physical coupling permits the nozzle 306 to vibrate with the distal end 208 of the elongate horn 204 to trigger standing waves that are the provide the
- the nozzle 306 extends away from the distal end 208 of the elongate horn 204 to reduce the likelihood of the liquid leaking onto and contaminating the distal end.
- the nozzle 306a is substantially cylindrical, comprises a plurality of delivery openings 308a, and fits into a receptacle 210a at the distal end 208a of the elongate horn 204.
- the nozzle 306b has a frusto-conical shape, comprises a single, elongate delivery opening 308b, and fits into a receptacle 210b at the distal end 208b of the elongate horn 204.
- the nozzle 306c has a trapezoidal cross-section, comprises a substantially rectangular delivery opening 308c, and fits into a receptacle 210c at the distal end 208c of the elongate horn 204.
- the size, shape, number, and arrangement of delivery opening(s) 308 in the nozzle 306 define the plume of mist generated by the misting device 100.
- the delivery opening(s) 308 are dimensioned to delivery an aerosol mist.
- each delivery opening has a maximum dimension (across the opening) of less than about 200 microns ( ⁇ ), more preferably, between about 50 and about 150 ⁇ .
- Preferred delivery openings are generally circular, but one of ordinary skill in the art may modify this to achieve specifically desired aerosol properties.
- the number of delivery openings is selected to deliver a desired misting flow. Nozzles with one delivery opening have been shown to produce a useful aerosol plume, and other nozzles with 6 and 7 openings have also produced useful aerosol plumes. Therefore, one of ordinary skill in the art may select from one to more than ten delivery openings.
- the distal end 208 of the elongate horn 204 may have surface features 212 disposed thereon to substantially prevent the formation of a mist from any liquid that may migrate away from the nozzle 306 and to the distal end 208 of the elongate horn 204. As shown in Fig. 5, these surface features 212 have an acute angle with respect to the axis of the horn to prevent any sonic motions from driving undesired liquids into the plume of liquids dispensed from the nozzle 306.
- a reservoir 302' feeds a nozzle 306' having an opening 310', e.g., via gravity, through a conduit 304'.
- the nozzle 306' fits into a receptacle 210' formed in the distal end 208' of an elongate horn 204' of a sonic generator (not shown).
- Activating the sonic generator energizes the liquid in the nozzle 306' to drive it through the delivery opening 310' to generate an aerosol plume.
- the height of the liquid column does not introduce significant flow variation during use and/or across multiple uses.
- a reservoir 1000 feeds a nozzle 1002 having a plurality of delivery openings 1004, e.g., via gravity, through conduit 1006.
- Elongate horn 1008 of sonic generator 1010 fits into receptacle 1012 proximate the base 1014 of reservoir 1000 to enable distal end 1016 of elongate horn 1008 to contact a rear wall 1018 of the nozzle 1002 (opposite the delivery openings 1004).
- Activating the sonic generator 1010 energizes the liquid in the nozzle 1002 to drive it through the delivery openings 1004 to generate an aerosol plume.
- a reservoir 1000' feeds a nozzle in the form of a cap 1002' (dimensioned to engage the distal end of the elongate horn 1008 of the sonic generator 1010) via gravity, through conduit 1006'.
- Activating the sonic generator 1010 energizes the liquid in the nozzle 1002' to drive it through the delivery openings 1004' to generate an aerosol plume 1020.
- the distal end of the horn and the nozzle should fit tightly to minimize energy loss due to inefficient motion transfer from the horn to the wall of the nozzle opposite the delivery openings to minimize heat buildup and to maximize control of the resulting aerosol plume.
- the elongate horn is generally metallic, preferably aluminum and/or titanium
- the nozzle should be made out of rigid plastic.
- the nozzle can be formed of metal or engineering plastic and machined or molded within appropriate tolerances to fit into the receptacle at the distal end of the elongate horn.
- a non-limiting list of useful materials include acetal resins (such as available from DuPont®
- the nozzle may be formed integrally with the reservoir and of the same materials.
- the nozzle may be formed from one of the foregoing materials and combined with a reservoir and/or conduit that are formed of less expensive and/or more easily handled materials.
- the housing may be fabricated by plastic injection molding, or any other suitable technique, and it is preferably ergonomic and adapted to fit comfortably in a hand of a user.
- the housing has a maximum linear dimension (length) of up to about 20 cm, more preferably, up to about 15 cm, and most preferably up to about 10 cm.
- the maximum dimension perpendicular to the length is 8 cm, more preferably, 5 cm.
- the conduit between the reservoir and nozzle is preferably sufficiently flexible for ease of manufacture. It is, however, preferred that the diameter of the conduit does not change with the application of pressure to the reservoir to dispense liquid therefrom. This permits control of the volume of liquid dispensed in an application of the aerosol plume.
- the liquid section is removable from the electromechanical section in a manner in which the nozzle is coupleable to the distal end of the elongate horn.
- the liquid section e.g., of Fig. 3, or any of Figs. 6-8
- the liquid section may be slidably engageable with the electromechanical section with the nozzle of Figs. 4A-4C or the like oriented to slide into the receptacle of the horn.
- the cap 1002', of the embodiment of Fig. 8 may snap fit over the distal end of the horn.
- the present invention is useful in the delivery of aerosol plumes of medication and/or moisturizing solutions in a more sanitary manner than currently provided.
- Sonic generation of aerosol plumes can provide very fine mists, having a droplet size between about 20 and about 60 ⁇ , given by the practical range of frequencies for the ultrasonic horn between 20kHz and 200kHz.
- a replaceable liquid section 508, such as shown in Fig. 3 can be slidably inserted into the electromechanical section 506.
- any protective covering e.g., cover 504 can be removed from the nozzle, 306, and the misting device 100 can be energized.
- the activation switch 408 is depressed, and the linear motor 310 drives the piston 312 to deliver a controlled force on the lower surface of the reservoir 314. This action forces liquid through conduit 304 to nozzle 306 and delivery opening(s) 308. This sequence may be repeated until the reservoir is emptied.
- the now-empty liquid section 508 can be removed and a new liquid section 508, including a new nozzle 306, is inserted. The new nozzle is not contaminated as a result of the previous use of the misting device.
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Special Spraying Apparatus (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Nozzles (AREA)
Abstract
Description
Claims
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA3001881A CA3001881A1 (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol misting device |
KR1020187015151A KR102650737B1 (en) | 2015-10-30 | 2016-10-28 | Sterile Aerosol Misting Device |
AU2016344187A AU2016344187B2 (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol misting device |
JP2018522138A JP6914930B2 (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol mist device |
MX2018005333A MX2018005333A (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol misting device. |
ES16791268T ES2844050T3 (en) | 2015-10-30 | 2016-10-28 | Aseptic Aerosol Misting Device |
BR112018008531-6A BR112018008531B1 (en) | 2015-10-30 | 2016-10-28 | PORTABLE MISTING DEVICE |
RU2018119688A RU2719932C2 (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol fogger |
IL258628A IL258628B (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol misting device |
CN201680063998.7A CN108348699B (en) | 2015-10-30 | 2016-10-28 | Sterile aerosol atomization device |
EP16791268.2A EP3368110B1 (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol misting device |
EP20211108.4A EP3799908A1 (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol misting device |
ZA2018/03554A ZA201803554B (en) | 2015-10-30 | 2018-05-29 | Aseptic aerosol misting device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562248682P | 2015-10-30 | 2015-10-30 | |
US62/248,682 | 2015-10-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2017075314A1 true WO2017075314A1 (en) | 2017-05-04 |
Family
ID=57233957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2016/059265 WO2017075314A1 (en) | 2015-10-30 | 2016-10-28 | Aseptic aerosol misting device |
Country Status (15)
Country | Link |
---|---|
US (1) | US10239085B2 (en) |
EP (2) | EP3368110B1 (en) |
JP (2) | JP6914930B2 (en) |
KR (1) | KR102650737B1 (en) |
CN (1) | CN108348699B (en) |
AU (1) | AU2016344187B2 (en) |
BR (1) | BR112018008531B1 (en) |
CA (1) | CA3001881A1 (en) |
ES (1) | ES2844050T3 (en) |
IL (1) | IL258628B (en) |
MA (1) | MA54688A (en) |
MX (1) | MX2018005333A (en) |
RU (1) | RU2719932C2 (en) |
WO (1) | WO2017075314A1 (en) |
ZA (1) | ZA201803554B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2728719C2 (en) | 2015-10-30 | 2020-07-30 | Джонсон энд Джонсон Консьюмер Инк. | Aseptic aerosol fogger |
KR102628081B1 (en) | 2015-10-30 | 2024-01-25 | 존슨 앤드 존슨 컨수머 인코포레이티드 | Unit dose sterile aerosol misting device |
ES2817024T3 (en) | 2015-10-30 | 2021-04-06 | Johnson & Johnson Consumer Inc | Aseptic Aerosol Sprayer |
US11246997B2 (en) * | 2018-09-25 | 2022-02-15 | Palo Alto Research Center Incorporated | Handheld filament extension atomizer for precision delivery of drugs and therapeutics |
EP3647058A1 (en) * | 2018-11-05 | 2020-05-06 | Ricoh Company, Ltd. | Liquid discharging head and liquid discharging apparatus |
CN211660579U (en) | 2019-11-13 | 2020-10-13 | 创科无线普通合伙 | Pressure cleaning machine |
USD1006212S1 (en) | 2020-04-03 | 2023-11-28 | Aptar Radolfzell Gmbh | Evaluation unit for inhalers |
USD943733S1 (en) * | 2020-04-30 | 2022-02-15 | Aptar Radolfzell Gmbh | Evaluation unit for inhalers |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0615470B1 (en) | 1991-12-04 | 1995-12-13 | The Technology Partnership Public Limited Company | Fluid droplet production apparatus and method |
US6863224B2 (en) | 2000-10-05 | 2005-03-08 | Omron Corporation | Liquid spray device |
US6901926B2 (en) | 1992-04-09 | 2005-06-07 | Omron Corporation | Ultrasonic atomizer, ultrasonic inhaler and method of controlling same |
WO2008097645A1 (en) * | 2007-02-08 | 2008-08-14 | Aerovectrx Corporation | Aerosol delivery systems and methods |
US7550897B2 (en) | 2004-04-07 | 2009-06-23 | The Technology Partnership Plc | Electronic drive system for a droplet spray generation device |
US7976135B2 (en) | 2006-10-12 | 2011-07-12 | The Technology Partnership Plc | Liquid projection apparatus |
US7992800B2 (en) | 2008-09-25 | 2011-08-09 | Micro Base Technology Corporation | Nebulization apparatus with a packaging and fixing structure |
US8286629B2 (en) | 2008-03-13 | 2012-10-16 | Omron Healthcare Co., Ltd. | Nebulizer and inhalation aid used therefor |
US20120318260A1 (en) | 2011-06-14 | 2012-12-20 | Microbase Technology Corp. | Portable nebulizing apparatus |
WO2014165694A2 (en) * | 2013-04-04 | 2014-10-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control Aned Prevention | Nasal aerosol delivery system |
US20150014433A1 (en) * | 2013-02-22 | 2015-01-15 | Temptu, Inc. | Systems and methods for ultrasonic spraying |
Family Cites Families (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB807080A (en) | 1956-02-28 | 1959-01-07 | Technical Ceramics Ltd | Ultrasonic spray |
US3812854A (en) | 1972-10-20 | 1974-05-28 | A Michaels | Ultrasonic nebulizer |
US4085893A (en) | 1974-03-20 | 1978-04-25 | Durley Iii Benton A | Ultrasonic humidifiers, atomizers and the like |
US4004736A (en) | 1976-06-01 | 1977-01-25 | The Boeing Company | Ultrasonic water jet |
US4301968A (en) | 1976-11-08 | 1981-11-24 | Sono-Tek Corporation | Transducer assembly, ultrasonic atomizer and fuel burner |
DE3122681C1 (en) * | 1981-06-06 | 1982-12-16 | Rowenta-Werke Gmbh, 6050 Offenbach | Ultrasonic inhaler |
EP0242460A1 (en) | 1985-01-18 | 1987-10-28 | SPECTRUM CONTROL, INC. (a Pennsylvania corporation) | Monomer atomizer for vaporization |
DE3627222A1 (en) * | 1986-08-11 | 1988-02-18 | Siemens Ag | ULTRASONIC POCKET SPRAYER |
US5104042A (en) | 1986-08-27 | 1992-04-14 | Atochem North America, Inc. | Ultrasonic dispersion nozzle with internal shut-off mechanism having barrier-fluid separation means incorporated therewith |
JPH03504821A (en) | 1989-03-27 | 1991-10-24 | アゼルバイジャンスキ ポリテフニチェスキ インスティテュト イメニ チェー.イルドリマ | Liquid ultrasonic atomization device |
DE4014904A1 (en) | 1990-05-09 | 1991-11-14 | Siemens Ag | ULTRASONIC SPRAYER FOR HAIR PAINT |
FR2669561B1 (en) | 1990-11-22 | 1995-03-03 | Dominique Dubruque | ULTRASONIC FLUID SPRAYING DEVICE. |
US5166000A (en) | 1991-10-10 | 1992-11-24 | Nanofilm Corporation | Method of applying thin films of amphiphilic molecules to substrates |
US5307640A (en) | 1993-01-25 | 1994-05-03 | E. I. Du Pont De Nemours And Company | Apparatus and method for producing frozen particles of a liquid |
CH686872A5 (en) * | 1993-08-09 | 1996-07-31 | Disetronic Ag | Medical Inhalationsgeraet. |
US5522385A (en) | 1994-09-27 | 1996-06-04 | Aradigm Corporation | Dynamic particle size control for aerosolized drug delivery |
JPH08332425A (en) | 1995-06-06 | 1996-12-17 | Funai Electric Co Ltd | Atomizer |
JP3190812B2 (en) | 1995-12-27 | 2001-07-23 | リズム時計工業株式会社 | Ultrasonic spray device |
JPH105711A (en) | 1996-06-26 | 1998-01-13 | Kazuo Yamaguchi | Washing device |
GB9805176D0 (en) | 1998-03-12 | 1998-05-06 | Rosslyn Precision Ltd | Ultrasonic seam bonding method and apparatus |
JP2001149473A (en) * | 1999-11-29 | 2001-06-05 | Omron Corp | Spray device |
BE1013167A3 (en) | 1999-12-03 | 2001-10-02 | Univ Catholique De Louvain Hal | Power supply procedure for a piezoelectric unit for an ultrasonic sputtererand the related system |
US6601581B1 (en) * | 2000-11-01 | 2003-08-05 | Advanced Medical Applications, Inc. | Method and device for ultrasound drug delivery |
US6478754B1 (en) | 2001-04-23 | 2002-11-12 | Advanced Medical Applications, Inc. | Ultrasonic method and device for wound treatment |
US6669103B2 (en) | 2001-08-30 | 2003-12-30 | Shirley Cheng Tsai | Multiple horn atomizer with high frequency capability |
US7348175B2 (en) * | 2002-03-15 | 2008-03-25 | St3 Development Corporation | Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products |
TW532236U (en) | 2002-06-25 | 2003-05-11 | Wen-Bin Chen | Modular water mist generating device |
GB2395437C (en) * | 2002-11-20 | 2010-10-20 | Profile Respiratory Systems Ltd | Improved inhalation method and apparatus |
CN100381083C (en) * | 2003-04-29 | 2008-04-16 | 韩力 | Electronic nonflammable spraying cigarette |
ATE483488T1 (en) * | 2004-04-02 | 2010-10-15 | Us Gov Health & Human Serv | AEROSOL DELIVERY SYSTEMS |
DE602004030544D1 (en) | 2004-06-09 | 2011-01-27 | Microflow Eng Sa | Improved modular liquid spray system |
WO2006013951A1 (en) * | 2004-08-02 | 2006-02-09 | Canon Kabushiki Kaisha | Chemical liquid cartridge and inhalation device using the same |
GB0508194D0 (en) | 2005-04-22 | 2005-06-01 | The Technology Partnership Plc | Pump |
US7896539B2 (en) * | 2005-08-16 | 2011-03-01 | Bacoustics, Llc | Ultrasound apparatus and methods for mixing liquids and coating stents |
FR2898468B1 (en) * | 2006-03-15 | 2008-06-06 | Lvmh Rech | PIEZOELECTRIC ELEMENT SPRAY DEVICE AND USE THEREOF IN COSMETOLOGY AND PERFUMERY. |
RU2411047C2 (en) * | 2006-08-01 | 2011-02-10 | Джапан Тобакко Инк. | Aerosol aspirator and method of aerosol aspiration |
EP2056935A2 (en) * | 2006-08-25 | 2009-05-13 | Eilaz Babaev | Portable ultrasound device for the treatment of wounds |
GB0620214D0 (en) | 2006-10-12 | 2006-11-22 | The Technology Partnership Plc | Liquid projection apparatus |
US8191982B2 (en) | 2006-10-12 | 2012-06-05 | The Technology Partnership Plc | Liquid projection apparatus |
GB0705102D0 (en) | 2007-03-19 | 2007-04-25 | The Technology Partnership Plc | Droplet spray generation device |
TW200903975A (en) | 2007-07-09 | 2009-01-16 | Micro Base Technology Corp | Piezoelectric miniature pump and its driving circuit |
JP5252890B2 (en) * | 2007-11-16 | 2013-07-31 | キヤノン株式会社 | Drug delivery device |
FR2927240B1 (en) | 2008-02-13 | 2011-11-11 | Oreal | SPRAY HEAD COMPRISING A SINGOTRODE, RUNWAYED BY A CANAL OF THE PRODUCT |
TW201011954A (en) | 2008-09-15 | 2010-03-16 | Micro Base Technology Corp | Conduction wire structure applied to the inner of micro piezoelectric pump |
JP5395423B2 (en) * | 2008-12-19 | 2014-01-22 | 花王株式会社 | Ultrasonic atomizer |
WO2010079486A1 (en) | 2009-01-08 | 2010-07-15 | Scentcom, Ltd. | Method and apparatus for computer controlled scent delivery |
US8297947B2 (en) | 2009-06-03 | 2012-10-30 | The Technology Partnership Plc | Fluid disc pump |
US8434473B2 (en) | 2009-06-26 | 2013-05-07 | Chen S. Tsai | Method or transporting a liquid for atomization and a method and devices for atomizing the same |
JP2011140007A (en) | 2010-01-08 | 2011-07-21 | Omron Healthcare Co Ltd | Thin sheet member washing apparatus |
TW201128154A (en) | 2010-02-12 | 2011-08-16 | Micro Base Technology Corp | Cooling and heat-dissipation system, and cooling device thereof |
CN101773894B (en) * | 2010-03-11 | 2012-06-20 | 清华大学 | Phase-controlled ultrasonic wave atomizing nozzle |
TW201204994A (en) | 2010-07-30 | 2012-02-01 | Microbase Technology Corp | Lighting device, cooling/heat dissipating system and its cooling module |
WO2012100205A2 (en) | 2011-01-21 | 2012-07-26 | Biodot, Inc. | Piezoelectric dispenser with a longitudinal transducer and replaceable capillary tube |
EP2694125A4 (en) | 2011-04-01 | 2015-01-14 | Christopher Burnside Gordon | Fluid jet cell harvester and cellular delivery system |
WO2013028934A1 (en) | 2011-08-23 | 2013-02-28 | Temptu , Inc. | Ultrasonic spraying device/air-assisted ultrasonic spraying device with advancing cartridge piston |
JP5652790B2 (en) * | 2011-09-22 | 2015-01-14 | オムロンヘルスケア株式会社 | Liquid spray device |
WO2013067041A1 (en) | 2011-11-01 | 2013-05-10 | Indrani Deo | Dispensing nozzle with an ultrasound activator |
JP6011015B2 (en) | 2012-05-16 | 2016-10-19 | 株式会社リコー | Liquid ejection head and image forming apparatus |
JP2014131391A (en) | 2012-12-28 | 2014-07-10 | Sanken Electric Co Ltd | Dc power supply device |
JP6499160B2 (en) * | 2013-05-17 | 2019-04-10 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | Cartridge for substance delivery module |
-
2016
- 2016-10-28 MA MA054688A patent/MA54688A/en unknown
- 2016-10-28 CN CN201680063998.7A patent/CN108348699B/en active Active
- 2016-10-28 MX MX2018005333A patent/MX2018005333A/en unknown
- 2016-10-28 US US15/337,064 patent/US10239085B2/en active Active
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- 2016-10-28 EP EP16791268.2A patent/EP3368110B1/en active Active
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- 2016-10-28 AU AU2016344187A patent/AU2016344187B2/en active Active
- 2016-10-28 JP JP2018522138A patent/JP6914930B2/en active Active
-
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- 2018-05-29 ZA ZA2018/03554A patent/ZA201803554B/en unknown
-
2021
- 2021-07-14 JP JP2021116220A patent/JP7210655B2/en active Active
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0615470B1 (en) | 1991-12-04 | 1995-12-13 | The Technology Partnership Public Limited Company | Fluid droplet production apparatus and method |
US6901926B2 (en) | 1992-04-09 | 2005-06-07 | Omron Corporation | Ultrasonic atomizer, ultrasonic inhaler and method of controlling same |
US6863224B2 (en) | 2000-10-05 | 2005-03-08 | Omron Corporation | Liquid spray device |
US7550897B2 (en) | 2004-04-07 | 2009-06-23 | The Technology Partnership Plc | Electronic drive system for a droplet spray generation device |
US7976135B2 (en) | 2006-10-12 | 2011-07-12 | The Technology Partnership Plc | Liquid projection apparatus |
WO2008097645A1 (en) * | 2007-02-08 | 2008-08-14 | Aerovectrx Corporation | Aerosol delivery systems and methods |
US8286629B2 (en) | 2008-03-13 | 2012-10-16 | Omron Healthcare Co., Ltd. | Nebulizer and inhalation aid used therefor |
US7992800B2 (en) | 2008-09-25 | 2011-08-09 | Micro Base Technology Corporation | Nebulization apparatus with a packaging and fixing structure |
US20120318260A1 (en) | 2011-06-14 | 2012-12-20 | Microbase Technology Corp. | Portable nebulizing apparatus |
US20150014433A1 (en) * | 2013-02-22 | 2015-01-15 | Temptu, Inc. | Systems and methods for ultrasonic spraying |
WO2014165694A2 (en) * | 2013-04-04 | 2014-10-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control Aned Prevention | Nasal aerosol delivery system |
Also Published As
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CN108348699B (en) | 2022-03-25 |
IL258628A (en) | 2018-06-28 |
CA3001881A1 (en) | 2017-05-04 |
JP2021166803A (en) | 2021-10-21 |
RU2018119688A (en) | 2019-12-03 |
ZA201803554B (en) | 2023-05-31 |
MA54688A (en) | 2021-11-17 |
BR112018008531B1 (en) | 2022-11-29 |
EP3368110B1 (en) | 2020-12-02 |
RU2018119688A3 (en) | 2019-12-03 |
EP3799908A1 (en) | 2021-04-07 |
IL258628B (en) | 2022-09-01 |
BR112018008531A2 (en) | 2018-10-30 |
EP3368110A1 (en) | 2018-09-05 |
BR112018008531A8 (en) | 2022-07-26 |
US20170128971A1 (en) | 2017-05-11 |
CN108348699A (en) | 2018-07-31 |
RU2719932C2 (en) | 2020-04-23 |
JP6914930B2 (en) | 2021-08-04 |
KR20180078281A (en) | 2018-07-09 |
ES2844050T3 (en) | 2021-07-21 |
AU2016344187A1 (en) | 2018-04-26 |
KR102650737B1 (en) | 2024-03-26 |
MX2018005333A (en) | 2018-05-17 |
JP7210655B2 (en) | 2023-01-23 |
US10239085B2 (en) | 2019-03-26 |
AU2016344187B2 (en) | 2021-07-29 |
JP2018536468A (en) | 2018-12-13 |
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