WO2017041717A1 - Composition fongicide, procédé et utilisation associée - Google Patents

Composition fongicide, procédé et utilisation associée Download PDF

Info

Publication number
WO2017041717A1
WO2017041717A1 PCT/CN2016/098336 CN2016098336W WO2017041717A1 WO 2017041717 A1 WO2017041717 A1 WO 2017041717A1 CN 2016098336 W CN2016098336 W CN 2016098336W WO 2017041717 A1 WO2017041717 A1 WO 2017041717A1
Authority
WO
WIPO (PCT)
Prior art keywords
component
components
composition according
composition
fungicidal composition
Prior art date
Application number
PCT/CN2016/098336
Other languages
English (en)
Inventor
James Timothy Bristow
Original Assignee
Rotam Agrochem International Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotam Agrochem International Company Limited filed Critical Rotam Agrochem International Company Limited
Publication of WO2017041717A1 publication Critical patent/WO2017041717A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • A01N47/14—Di-thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals

Definitions

  • the present invention relates to a fungicidal composition.
  • the present invention also related to a method to prevent and/or treat fungal infestations in plants and plant parts, including by applying the aforementioned fungicidal composition.
  • Fungal diseases represent a major threat to economically important agricultural crops, such as cereals, fruits and vegetables.
  • the yield of plants, for example, grape, apple, tomato and rice, are adversely impacted by fungal diseases, such as downy mildew (for example, caused by Plasmopara viticola and Pseudoperonopora cubensis) and late blight (caused by Phytophthora infestans) .
  • downy mildew caused by Plasmopara viticola, is a highly destructive disease of grapevines in all grape-growing areas under conditions of favorable humidity and temperature. Symptoms of such infestations include yellow circular spots with an oily appearance (oilspots) on the leaves.
  • Dimethomorph is a known, systemic fungicidally active substance and is commercially available (see, for example, “The Pesticide Manual” 14th edition (2006) , The British Crop Protection Council, pages 347 et seq. ) . Dimethomorph has two isomers. The structures of isomers, the E isomer and the Z isomer, are shown below:
  • Dimethomorph is effective against Oomycetes, especially Peronosporaceae in vines, potatoes, tomatoes and other crops.
  • CN101548686A discloses a fungicide composition comprising dimethomorph.
  • a fungicidal composition comprising dimethomorph, fosetyl-aluminium and a dithiocarbamate fungicide is employed for treating fungal diseases.
  • dimethomorph, fosetyl-aluminium and a dithiocarbamate fungicides is characterized by different modes of action and exhibits a considerable synergistic effect, allowing a higher fungicidal activity to be obtained than that envisaged on the basis of the activities of the individual components dimethomorph, fosetyl-aluminium and the dithiocarbamate.
  • the present invention provides a fungicidal composition
  • a fungicidal composition comprising components (A) dimethomorph, (B) fosetyl-aluminium and (C) a dithiocarbamate.
  • the present invention also provides, in a further aspect, a method to prevent and/or treat fungal infestations in plants and plant parts by applying to the plants and/or the plant parts and/or their surroundings components (A) dimethomorph, (B) fosetyl-aluminium and (C) a dithiocarbamate.
  • the present provides the use of a combination of components (A) dimethomorph, (B) fosetyl-aluminium and (C) a dithiocarbamate in the treatment or prevention of a fungal infestation in plants.
  • the invention also relates to a plant or plant part treated with a composition or combination hereinbefore defined, either before infestation by a fungus or treated to combat an existing fungal infection.
  • Plant refers to all plant and plant populations such as desired and undesired wild plants or crop plants.
  • Plant parts refers to all parts and organs of plants, such as shoots, leaves, needles, stalks, stems, fruit bodies, fruits, seeds, roots, tubers and rhizomes.
  • the word “surrounding” refers to the place on which the plants are growing, the place on which the plant propagation materials of the plants are sown or the place on which the plant propagation materials of the plants will be sown.
  • At least one designates a number of the respective compounds of 1, 2, 3, 4, 5, 6, 7, 8, 9 or more, preferably 1, 2, or 3.
  • fungicidal composition comprising components (A) dimethomorph, (B) fosetyl-aluminium and (C) a dithiocarbamate on the plants, plant parts or the surroundings thereof, particularly on crops, for example cereals, cucurbitaceae, fruits, leguminous plants, oil plants, ornamentals, tobacco and vegetables, an excellent performance in preventing and treating fungal infestations may be observed.
  • crops for example cereals, cucurbitaceae, fruits, leguminous plants, oil plants, ornamentals, tobacco and vegetables
  • the activity exhibited is greater than that expected from the activity of the individual components, indicating a significant synergistic effect.
  • Component (A) dimethomorph
  • Component (A) may be present in the composition of the present invention in any suitable amount and is generally present in an amount of from about 1% to about 75% by weight of the composition, preferably from about 1% to about 50% by weight of the composition, more preferably from about 3% to about 20% by weight of the composition, most preferably from about 3% to about 10% by weight of the composition.
  • dimethomorph is present in an amount of about 7% by weight of the composition.
  • Component (B) fosetyl-aluminium
  • fosetyl-aluminium is present in an amount of about 50% by weight of the composition.
  • fosetyl-aluminium is present in an amount of about 60% by weight of the composition.
  • Component (C) a dithiocarbamate
  • a dithiocarbamate may be any fungicidally active dithiocarbamate compound or a combination of two or more fungicidally active dithiocarbamate compounds. Such compounds are known in the art and are commercially available.
  • the dithiocarbamate compound is preferably one or more compounds selected from amobam, asomate, azithiram, carbamorph, cufraneb, cuprobam, disulfiram, ferbam, metam, nabam, tecoram, thiram, urbacide, and ziram; cyclic dithiocarbamate fungicides, for example dazomet, etem and milneb; and polymeric dithiocarbamate fungicides, for example mancopper, maneb, metiram, polycarbamate, propineb and zineb.
  • the dithiocarbamate fungicide is selected from metam, thiram, ziram, dozomet, metiram and propineb and combinations thereof. In certain embodiments, the dithiocarbamate fungicide is selected from thiram, metiram, propineb, and mixtures thereof.
  • the dithiocarbamate compound does not include mancozeb.
  • Component (C) one or more dithiocarbamate fungicides, may be present in the composition in any suitable amount and is generally present in an amount of from about 1% to about 85% by weight of the composition, preferably from about 1% to about 70% by weight of the composition, more preferably from about 1% to about 50% by weight of the composition.
  • the components (A) (B) and (C) together may be present in the composition in any suitable amount and are generally present in a total amount of from about 2% to about 95% by weight of the composition, preferably from about 10% to about 90% by weight of the composition more preferably from about 15% to about 90% by weight of the composition.
  • Components (A) and (B) may be present in the composition in any suitable amounts relative to each other, to provide the enhanced or synergistic effect of the mixture.
  • the weight ratio of components (A) and (B) in the composition is preferably in the range of from 25: 1 to 1: 25, 20: 1 to 1: 20 or 15: 1 to 1: 15, more preferably 10: 1 to 1: 10.
  • a weight ratio of from 1: 3 to 1: 10 is advantageous in many embodiments, more preferably from 1: 5 to 1: 10.
  • the weight ratio of components (A) and (B) in the composition is about 1: 7.
  • the weight ratio of components (A) and (B) in the composition is about 1: 9.
  • Component (C) may be present in the composition in any suitable amount relative to the other components to provide the enhanced or synergistic effect of the mixture.
  • the weight ratio between the total amount of components (A) + (B) and component (C) in the composition is preferably in the range of from 25: 1 to 1: 25, 20: 1 to 1: 20 or 15: 1 to 1: 15, more preferably 10: 1 to 1: 10.
  • composition of the present invention comprising components (A) , (B) and (C) may optionally comprise one or more auxiliaries.
  • auxiliaries employed in the composition will depend upon the type of formulation and/or the manner in which the formulation is to be applied by the end user. Formulations incorporating the composition of the present invention are described hereinafter.
  • Suitable auxiliaries which may be comprised in the composition according to the invention are all customary formulation adjuvants or components, such as extenders, carriers, solvents, surfactants, stabilizers, anti-foaming agents, anti-freezing agents, preservatives, antioxidants, colorants, thickeners, solid adherents and inert fillers.
  • auxiliaries are known in the art and are commercially available. Their use in the formulation of the compositions of the present invention will be apparent to the person skilled in the art.
  • the composition may further comprise one or more inert fillers.
  • inert fillers are known in the art and are available commercially. Suitable fillers include, for example, natural ground minerals, such as kaolins, aluminas, talc, chalk, quartz, attapulgite, montmorillonite, and diatomaceous earth, or synthetic ground minerals, such as highly dispersed silicic acid, aluminum oxide, silicates, and calcium phosphates and calcium hydrogen phosphates.
  • Suitable inert fillers for granules include, for example, crushed and fractionated natural minerals, such as calcite, marble, pumice, sepiolite, and dolomite, or synthetic granules of inorganic and organic ground materials, as well as granules of organic material, such as sawdust, coconut husks, corn cobs, and tobacco stalks.
  • the composition optionally includes one or more surfactants which are preferably non-ionic, cationic and/or anionic in nature and surfactant mixtures which have good emulsifying, dispersing and wetting properties, depending on the nature of the active compound to be formulated.
  • surfactants are known in the art and are commercially available.
  • Suitable anionic surfactants can be both so-called water-soluble soaps and water-soluble synthetic surface-active compounds.
  • Soaps which may be used are the alkali metal, alkaline earth metal or substituted or unsubstituted ammonium salts of higher fatty acid (C 10 to C 22 ) , for example the sodium or potassium salt of oleic or stearic acid, or of natural fatty acid mixtures.
  • the surfactant can be an emulsifier, dispersant or wetting agent of ionic or nonionic type.
  • examples which may be used are salts of polyacrylic acids, salts of lignosulphonic acid, salts of phenylsulphonic or naphthalenesulphonic acids, polycondensates of ethylene oxide with fatty alcohols or with fatty acids or with fatty amines, substituted phenols, especially alkylphenols, sulphosuccinic ester salts, taurine derivatives, especially alkyltaurates, or phosphoric esters of polyethoxylated phenols or alcohols.
  • the presence of at least one surfactant is generally required when the active compound and/or the inert carrier and/or auxiliary/adjuvant are insoluble in water and the vehicle for the final application of the composition is water.
  • the composition optionally further comprises one or more polymeric stabilizers.
  • suitable polymeric stabilizers that may be used in the present invention include, but are not limited to, polypropylene, polyisobutylene, polyisoprene, copolymers of monoolefins and diolefins, polyacrylates, polystyrene, polyvinyl acetate, polyurethanes or polyamides. Suitable stabilizers are known in the art and commercially available.
  • surfactants and polymeric stabilizers mentioned above are generally believed to impart stability to the composition, in turn allowing the composition to be formulated, stored, transported and applied.
  • Suitable anti-foam agents include all substances which can normally be used for this purpose in agrochemical compositions. Suitable anti-foam agents are known in the art and are available commercially. Particularly preferred antifoam agents are mixtures of polydimethylsiloxanes and perfluroalkylphosphonic acids, such as the silicone anti-foam agents, commercially available from GE or Compton.
  • Suitable organic solvents may be selected from all customary organic solvents which thoroughly dissolve the active compounds employed. Again, suitable organic solvents for the active components (A) , (B) and (C) are known in the art. The following may be mentioned as being preferred: N-methyl pyrrolidone, N-octyl pyrrolidone, cyclohexyl-1-pyrrolidone; or SOLVESSO TM 200, a mixture of paraffinic, isoparaffinic, cycloparaffinic and aromatic hydrocarbons. Suitable solvents are commercially available.
  • Suitable preservatives include all substances which can normally be used for this purpose in agrochemical compositions of this type and again are well known in the art. Suitable examples that may be mentioned include (from Bayer AG) and (from Bayer AG) .
  • Suitable antioxidants are all substances which can normally be used for this purpose in agrochemical compositions, as is known in the art. Preference is given to butylated hydroxytoluene.
  • Suitable thickeners include all substances which can normally be used for this purpose in agrochemical compositions.
  • thickeners are known in the art and available commercially.
  • the fungicidal composition may further comprise one or more solid adherents.
  • adherents are known in the art and available commercially. They include organic adhesives, including tackifiers, such as celluloses of substituted celluloses, natural and synthetic polymers in the form of powders, granules, or lattices, and inorganic adhesives such as gypsum, silica, or cement.
  • composition according to the invention may also comprise water.
  • compositions according to the present invention comprise the following combinations of components:
  • compositions of the present invention can be used in the agricultural sector and related fields of use for preventing and/or treating diseases caused by fungal pathogens for example, but not limited to:
  • rice blast (Magnaporthe grisea) , seed decay, seedling blight and damping-off (Pythium spp., Fusarium spp., Diplodia spp., Rhizoctonia spp. and Penicillium spp. ) , southern corn leaf blight, millet downy mildew, downy mildew, bakanae disease, and rubber tree stripe canker in cereals, such as rice, corn, millet;
  • Sooty blotch complex (Peltaster fructicola, Geastrumia polystigmatis, Leptodontidium elatius, Gloeodes pomigena) , flyspeck (Schizothirium pomi; [anamorph] : Zygophiala jamaicensis) , bitter rot (Glomerella cingulata) , black rot (Botryosphaeria obtusa) , brooks' s pot (Mycosphaerella pom; , [anamorph] : Cylindrosporium) , sooty blotch (Gloeodes pomigena) , cedar-apple rust (Gymnosporangium juniperi-virginianae) , quince rust (Gymnosporangium clavipes) , necrotic leaf blotch (disorder, not associated with any bacteria or fungi
  • Anthracnose Fruit rot (Colletotrichum acutatum) , botrytis blight (Botrytis cinerea) , cherry scab (Venturia cerasi) , leaf spot (Blumeriella jaapii; [anamorph] : Phloeosporella padi) , black knot (Dibotryon morbosum) , black spot (Guignardia citricarpa) , anthracnose (Colletotrichum gloeosporiodes) , constriction canker or Fusicoccum canker or Phomopsis shoot blight (Phomopsis amygdali) , Peach scab (Cladosporium carpophilum, [teleomorph] : Venturia carpophila; Cladosporium spp.
  • Fabraea leaf spot (Fabraea maculata; [anamorph] : Entomosporium mespili) , Quince rust; pecan scab (Cladosporium caryigenum) , anthracnose (Glomerella cingulata; [anamorph] : Colletotrichum gloeosporioides) , plum pockets (Taphrina communis) , rust (Tranzschelia discolor f. sp. persica) , Botrytis rot or botryis bunch rot (Botrytis cinerea) , Grape ripe-rot (Colletotrichum spp.
  • Anthracnose (Colletotrichum lindemuthianum) , Ascochyta blight (Ascochyta fabae) , Rust (Uromyces appendiculatus, Uromyces viciae-fabae) , Botrytis grey mould (Botrytis cinerea) , Ascochyta blight or Black spot (Ascochyta rabiei, Ascochyta spp. ) , Chocolate spot (Botrytis fabae) , Cercospora leaf spot (Cercospora zonat) in leguminous plants, such as beans, broad beans, faba beans, chickpeas, field peas, lentils and vetch;
  • Botrytis blight or gray mold Botrytis cinerea
  • White mold Sterotinia spp.
  • Alternaria leaf spot Alternaria spp.
  • Fusarium wilt Fusarium wilt
  • Damping-off Pythium spp. and Phytophthora spp.
  • Rhizoctonia blight or stem canker Rhizoctonia solani; [teleomorph] : Thanatephorus cucumeris
  • rust Pierinia spp.
  • botrytis leaf spot Botrytis cinerea
  • powdery mildew Erisyphe, Leveillula, Microsphaera, Podosphaera, Odium, and Sphaerotheca spp.
  • black spot Downy mildew (Peronospora arborescens) in ornamentals;
  • stem rot Sterotium rolfsii; [teleomorph] : Athelia rolfsii) , Black scurf (Rhizoctonia solani; [teleomorph] : Thanatephorus cucumeris) , Neck rot (Botrytis spp. ) , verticillium wilt (Verticillium albo-atrum) , Rust (Puccinia spp.
  • anthracnose Coldracnose
  • Colletotrichum dematium Colletotrichum gloeosporioides; [teleomorph] : Glomerella cingulata
  • septoria leaf spot Septoria lycopersici
  • Ring spot Mycosphaerella brassicicola
  • Alternaria leaf spot Alternaria spp.
  • Cercospora leaf spot (Cercospora carotae) , Late blight (Septoria apiicola, Phytophthora infestans) , Septoria (Septoria lactucae, Septoria lycopersici) , Septoria leaf spot (Septoria apiicola) , Purple blotch (Alternaria porri) , Early blight or Target spot (Alternaria solani) , Downy mildew (Bremia lactucae; Plasmopara lactucae-radicis) , phytophthora alternaria, Grey leaf spot (Stemphylium solani, Stemphylium floridanum, Stemphylium botryosum) in vegetables, such as alfalfa, asparagus, bulb onions, garlic, cabbages, cauliflowers, brussel sprouts, broccoli, capsicums, eggplants, peppers, carrots, celery, Chinese cabbage, lettuces, onions, potatoes, and tomatoes.
  • compositions or techniques of the present invention can be used in the agricultural sector and related fields of use for preventing and/or treating diseases caused by fungal pathogens for example, but not limited to:
  • the fungal disease to be treated and/or prevented may be selected in particular from the group comprising downy mildew and late blight.
  • composition and techniques of the present invention exhibit surprisingly high effectiveness in treating and/or preventing fungal diseases caused by fungal pathogens, particularly Plasmospara viticola, Phytophthora infestans and Pseudoperonospora cubensis.
  • composition and techniques according to the present invention are suitable for protecting plants of a wide range of crops, including the following:
  • Cereals such as wheat, barley, rye, oats, corn, rice, sorghum, triticale and related crops; beet, including sugar beet and fodder beet; fruit, such as pomes, stone fruit and soft fruit, such as apples, grapes, pears, plums, peaches, almonds, cherries, and berries, for example strawberries, raspberries and blackberries; leguminous plants, such as beans, lentils, peas, soybeans; oil plants, including rape, mustard, and sunflowers; cucurbitaceae, such as marrows, cucumbers, melons, water melons, courgettes, and pumpkins; fibre plants, including cotton, flax, hemp, and jute; citrus fruit, such as oranges, lemons, grapefruit and mandarins; vegetables, such as spinach, lettuce, asparagus, cabbages, carrots, onions, tomatoes, potatoes, paprika, eggplants, and peppers; as well as ornamentals, including flowers, such as roses, shrubs, broad
  • composition and techniques of the present invention are applied to fruits, vegetables and cucurbitaceae. In some embodiments, the composition and techniques of the present invention are applied to grapes, tomatoes, eggplants, peppers, cucumbers, water melons, courgettes and pumpkins.
  • composition and techniques of the present invention are particularly effective in preventing and/or treating Plasmospara viticola in grapes; Phytophthora infestans in tomatoes, eggplants and peppers; and Pseudoperonospora cubensis in melons, water melons, courgettes, pumpkins and cucumbers, and their plant parts, preferably when employing the following components:
  • weight ratio of the components (A) and (B) in the composition is about 1: 7, or 1: 9.
  • composition and techniques of the present invention are particularly effective in preventing and/or treating Plasmospara viticola in grapes; Phytophthora infestans in tomatoes, eggplants and peppers; and Pseudoperonospora cubensis in melons, water melons, courgettes, pumpkins and cucumbers, and their plant parts by employing a combination of components (A) dimethomorph, (B) fosetyl-aluminium and (C) a dithiocarbamate, wherein component (A) is 7% by weight of the composition; and wherein the component (B) is 50% by weight of the composition.
  • the combination of components (A) dimethomorph, (B) fosetyl-aluminium and (C) thiram or metiram or propineb may be used to prevent and/or treat fungal infestations in plants and plant parts.
  • the combination of components (A) dimethomorph, (B) fosetyl-aluminium and (C) thiram or metiram or propineb may be used to prevent and/or treat Plasmospara viticola in grape; Phytophthora infestans in tomatoes, eggplants and peppers; and Pseudoperonospora cubensis in melons, water melons, courgettes, pumpkins and cucumbers, and their plant parts.
  • Each of the components (A) , (B) and (C) can be applied to the foliage of the plants, plant parts, soil or surroundings.
  • composition of the present invention may contain or be mixed with one or more other pesticides, such as other fungicides, insecticides and nematicides, growth regulators and fertilizers.
  • pesticides such as other fungicides, insecticides and nematicides, growth regulators and fertilizers.
  • the components (A) , (B) and (C) may be applied and used in pure form, as a solid active compound, for example, in a specific particle size, or preferably together with at least one of the auxiliary or adjuvant components described above, as are customary in formulation technology, such as extenders, for example solvents or solid carriers, or surface-active compounds (surfactants) , as described in more detail above.
  • the components (A) , (B) and (C) are in the form of a formulation composition with one or more of the aforementioned customary formulation auxiliaries.
  • formulation types for pre-mix compositions are:
  • water-soluble concentrates SL
  • emulsifiable concentrates EC
  • EW emulsions
  • ME micro-emulsions
  • SC suspension concentrate
  • OD oil-based suspension concentrates
  • FS flowable suspensions
  • WG water-dispersible granules
  • WP water-soluble granules
  • SP water soluble powders
  • GR granules
  • CG encapsulated granules
  • FG fine granules
  • GG macrogranules
  • SE capsule suspensions
  • MG microgranules
  • Preferred formulation types are water-dispersible granules (WG) and suspension concentrates (SC) .
  • either straight (that is undiluted) or diluted with a suitable solvent, especially water, plants, plant parts and/or their surrounding can be treated and protected against damage, for example by fungal pathogen (s) , by spraying, pouring or immersing.
  • a suitable solvent especially water, plants, plant parts and/or their surrounding
  • the formulated composition may for example be applied in spray form, for example employing appropriate dilutions.
  • Water is a most suitable diluent for spray applications.
  • the rates of application of the components and the compositions of the present invention may vary, for example, according to the type of use, the type of crop, the specific formulation type, the type of plants being targeted, but is such that the active compounds in the combination are provided in an effective amount to provide the desired action (such as disease or pest control) .
  • the application rate of the components and the composition for a given set of conditions can readily be determined by routine trials.
  • Suitable application rates for each of dimethomorph and fosetyl-aluminium in the synergistic fungicidal composition lie in the range of from 50 to 5000 gram per hectare. In general, satisfactory results will be obtained when employing from 100 to 400 gram per hectare, for example 210 gram per hectare, of dimethomorph and from 750 to 3000 gram per hectare, for example 1500 or 1800 gram per hectare, of fosetyl-aluminium.
  • the application rate for the dithiocarbamate of component (C) may vary within a wide range, for example from 20 to 200,000 gram per hectare, more preferably from 30 to 150,000 gram per hectare. In a number of preferred embodiments, component (C) is applied at a rate of from 20 to 3000 gram per hectare. In still other embodiments, component (C) is applied at a rate of from 100,000 to 200,000 gram per hectare.
  • the components (A) , (B) and (C) may be applied with the methods known in the art. These methods include coating, spraying, dipping, soaking, injection, irrigation and the like.
  • the spray treatment typically involves foliar application until there is run-off of the formulation.
  • the components may be applied at a spray volume of from 100 to 1000 liters per hectare of crop locus, depending on the growth stage of the crop.
  • the spray volume may be readily determined for a given set of conditions, as is known in the art.
  • the present invention provides a method and use for the components (A) , (B) and (C) .
  • the active components (A) , (B) and (C) may be applied to the plants, plant parts and/or their surroundings where control is desired.
  • the components may be applied either simultaneously and/or in succession at short intervals, for example on the same day.
  • the components (A) , (B) and (C) may be applied to the plant, one or more parts thereof (such as leaves or seeds) , or the plant surroundings in any order.
  • Each compound may be applied just once or a plurality of times.
  • each of the components (A) , (B) and (C) are applied a plurality of times, in particular from 1 to 5 times, more preferably 2 times.
  • the active components (A) , (B) and (C) may be applied in any suitable form, as described above.
  • the active components will be applied as formulations, that is compositions comprising one or more of the active components together with further carriers, surfactants or other application-promoting adjuvants customarily employed in formulation technology, as discussed above.
  • the components (A) , (B) and (C) may be applied in any desired sequence, any combination, consecutively and/or simultaneously.
  • compounds (A) , (B) and (C) are applied simultaneously in the present invention, they may be applied as a composition containing components (A) , (B) and (C) , in which case components (A) , (B) and (C) can each be obtained from a separate formulation source and mixed together.
  • the components (A) , (B) and (C) are combined by the end user in known manner using separate formulations of one or more of components (A) , (B) and (C) , known in the art as a tank-mix, ready-to-apply, spray broth, or slurry.
  • components (A) , (B) and (C) can be obtained as a single formulation mixture source, known as a pre-mix, concentrate, formulated compound or product.
  • components (A) , (B) and (C) are provided in the form of a composition of the present invention.
  • Components (A) , (B) and (C) may optionally be employed with other pesticides.
  • one or more other pesticide formulations may be included in the final tank-mix prepared by the end user.
  • one or more other pesticides may be included in the compositions of components (A) , (B) and (C) .
  • components (A) , (B) and (C) are applied simultaneously, with component (C) being applied from a separate formulation source and mixed together with the composition comprising components (A) and (B) .
  • components (A) , (B) and (C) are applied together, preferably in the form of a composition of the present invention, as described above.
  • compositions according to the invention are distinguished by the fact that they are especially well tolerated by plants and are environmentally friendly.
  • composition, method and use of the present invention are further illustrated by the following specific examples.
  • Examples 1 and 2 are comparative examples.
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • a suspension concentrate formulation was prepared from the components summarized in the following table:
  • Silicone oil (in the form of a 75% emulsion in water) 10g Water Balance to 1L
  • Example 5 7% Dimethomorph + 50% Fosetyl-aluminium + 20% Asomate WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 8 7% Dimethomorph + 50% Fosetyl-aluminium + 1% Cufraneb WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 9 7% Dimethomorph + 20% Fosetyl-aluminium + 20% Cuprobam WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 10 7% Dimethomorph + 20% Fosetyl-aluminium + 25% Disulfiram WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 12 3.5% Dimethomorph + 25% Fosetyl-aluminium + 20% Ferbam WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 13 25% Dimethomorph + 25% Fosetyl-aluminium + 5% Mancopper WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 14 25% Dimethomorph + 25% Fosetyl-aluminium + 5% Maneb SC
  • a suspension concentrate formulation was prepared from the components summarized in the following table:
  • Example 15 5% Dimethomorph + 37.5% Fosetyl-aluminium + 25% Metam WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 16 5% Dimethomorph + 37.5% Fosetyl-aluminium + 5% Milneb WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 17 7% Dimethomorph + 50% Fosetyl-aluminium + 3.5% Nabam SC
  • a suspension concentrate formulation was prepared from the components summarized in the following table:
  • Example 18 5% Dimethomorph + 25% Fosetyl-aluminium + 5% Polycarbamate EC
  • An emulsion concentrate formulation was prepared from the components summarized in the following table:
  • Example 19 4% Dimethomorph + 30% Fosetyl-aluminium + 18% Propineb WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 20 15% Dimethomorph + 30% Fosetyl-aluminium + 10% Tecoram WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 21 7% Dimethomorph + 50% Fosetyl-aluminium + 30% Thiram WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 22 10% Dimethomorph + 10% Fosetyl-aluminium + 40% Urbacide WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 23 7% Dimethomorph + 50% Fosetyl-aluminium + 17% Zineb WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 24 3.5% Dimethomorph + 25% Fosetyl-aluminium + 45% Ziram WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • Example 25 7% Dimethomorph + 50% Fosetyl-aluminium + 30% Metiram WG
  • a water dispersible granule formulation was prepared from the components summarized in the following table:
  • the severity of fungal infestation is indicated in terms of the percentage of the plant observed to be infested with the fungus.
  • the expected activity for a given combination of three active compounds can be calculated by the so called “Colby equation” (see S. R. Colby, “Calculating Synergistic and Antagonistic Responses of Herbicide Combinations” , Weeds 1967, 15, 20-22) :
  • A the activity percentage of compound A when active compound A is empolyed at an application rate of m g/ha;
  • E the percentage of estimated activity when compounds A, B and C are empolyed together at an application rate of m g/ha, n g/ha and r g/ha;
  • Young grape plants were sprayed with a conidial suspension of Plasmopara viticola, and incubated at conditions of 20°C and 100% relative atmospheric humidity for 48 hours.
  • the compositions of Examples 1 to 25 above were diluted with water and then sprayed on the plants.
  • the treated plants were held in a greenhouse at conditions of 15°C and 80% relative atmospheric humidity for 15 days, after which the severity of fungal infestation of the plants was examined.
  • Young tomato plants were sprayed with a conidial suspension of Phytophthora infestans, and incubated at conditions of 20°C and 100% relative atmospheric humidity for 48 hours.
  • the compositions of Examples 1 to 25 above were diluted with water and then sprayed on the plants.
  • the treated plants were held in a greenhouse at conditions of 15°Cand 80% relative atmospheric humidity for 15 days, after which the severity of fungal infestation of the plants was examined.
  • Table B demonstrate a surprisingly high level of antifungal activity exhibited by combinations of dimethomorph, fosetyl-aluminium and a dithiocarbamate and indicate a clear synergy.
  • Young cucumber plants were sprayed with a conidial suspension of Pseudoperonospora cubensis, and incubated at conditions of 20°C and 100% relative atmospheric humidity for 48 hours.
  • the compositions of Examples 1 to 25 above were diluted with water and then sprayed on the plants.
  • the treated plants were held in a greenhouse at conditions of 15°C and 80% relative atmospheric humidity for 15 days, after which the severity of fungal infestation of the plants was examined.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne une composition fongicide, la composition comprenant les composants (A) diméthomorphe, (B) fosétyl-aluminium et (C) un dithiocarbamate. L'invention concerne également un procédé de traitement et/ou de prévention d'infestations fongiques comprenant l'application à des plantes, des parties de plantes et/ou à leur environnement des composants (A), (B) et (C). L'invention concerne également l'utilisation des composants (A), (B) et (C) dans le traitement et/ou la prévention d'infestations fongiques de plantes.
PCT/CN2016/098336 2015-09-08 2016-09-07 Composition fongicide, procédé et utilisation associée WO2017041717A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1515897.5A GB2542135B (en) 2015-09-08 2015-09-08 A fungicidal composition, method and use of the same
GB1515897.5 2015-09-08

Publications (1)

Publication Number Publication Date
WO2017041717A1 true WO2017041717A1 (fr) 2017-03-16

Family

ID=54345935

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2016/098336 WO2017041717A1 (fr) 2015-09-08 2016-09-07 Composition fongicide, procédé et utilisation associée

Country Status (2)

Country Link
GB (1) GB2542135B (fr)
WO (1) WO2017041717A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280348A1 (fr) * 1987-01-30 1988-08-31 Shell Internationale Researchmaatschappij B.V. Composition fongicides
CN101548686A (zh) * 2007-05-25 2009-10-07 天津市东方农药有限公司 一种含烯酰吗啉的杀菌剂组合物
CN102245018A (zh) * 2008-12-09 2011-11-16 巴斯夫欧洲公司 包含烯酰吗啉和二硫代氨基甲酸酯的植物保护配制剂

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280348A1 (fr) * 1987-01-30 1988-08-31 Shell Internationale Researchmaatschappij B.V. Composition fongicides
CN101548686A (zh) * 2007-05-25 2009-10-07 天津市东方农药有限公司 一种含烯酰吗啉的杀菌剂组合物
CN102245018A (zh) * 2008-12-09 2011-11-16 巴斯夫欧洲公司 包含烯酰吗啉和二硫代氨基甲酸酯的植物保护配制剂

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEN, ZHAO ET AL.: "Toxicity Test of the Systemic Fungicides for Rubber White Root Disease in Laboratory", AGROCHEMICALS, vol. 46, no. 9, 30 September 2007 (2007-09-30) *
CONG, XIN-LI ET AL.: "Summary of Pesticide Use in Chemical Control of Potato Late Blight", CHINESE JOURNAL OF PESTICIDES, vol. 44, no. 5, 31 May 2005 (2005-05-31) *

Also Published As

Publication number Publication date
GB2542135B (en) 2020-04-01
GB201515897D0 (en) 2015-10-21
GB2542135A (en) 2017-03-15

Similar Documents

Publication Publication Date Title
EP3081086B1 (fr) Composition insecticide synergique comprenant imidacloprid, bifenthrin et abamectin
US20230270113A1 (en) Fungicidal mixtures
WO2015192717A1 (fr) Composition insecticide synergique comprenant des insecticides néonicotinoïdes et des insecticides pyréthroïdes
US10136647B2 (en) Synergistic Bacillus thuringiensis subsp. kurstaki and chlorantraniliprole mixtures for diamondback moth, beet armyworm, sugarcane borer, soybean looper and corn earworm control
WO2017024889A1 (fr) Composition insecticide synergique
CN114223665B (zh) 一种杀菌组合物用于防治植物致病真菌的用途
WO2023135535A1 (fr) Mélanges fongicides comprenant une combinaison contenant des fongicides de phtalimide
WO2016074519A1 (fr) Composition herbicide et procédé pour réguler la croissance de végétaux
AU2015271898B2 (en) A synergistic composition comprising insecticides and fungicides
US10568329B2 (en) Synergistic insecticidal composition
AU2015234288B2 (en) A synergistic insecticidal composition
CN110573016B (zh) 杀真菌组合物及其用途
WO2017041717A1 (fr) Composition fongicide, procédé et utilisation associée
WO2015161749A1 (fr) Composition fongicide synergique comprenant du cymoxanil et du chlorothalonil
CN107593710B (zh) 一种杀菌组合物
TWI789356B (zh) 協同性殺真菌組成物及其用途
WO2018024149A1 (fr) Composition herbicide et procédé pour réguler la croissance des plantes
CN107637601B (zh) 一种杀菌组合物
CN107593711B (zh) 一种杀菌组合物
CN112244034A (zh) 一种杀菌组合物
TW202408363A (zh) 扶吉胺(fluazinam)之殺真菌組合及其用途
BR112017022487B1 (pt) Composição fungicida sinérgica e uso da mesma
WO2020173218A1 (fr) Composition synergique comprenant des insecticides et des fongicides
BR112020016153A2 (pt) Composição fungicida e utilização da mesma no controle de infestações fúngicas indesejadas
GB2576125A (en) Synergistic insecticidal composition

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16843655

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 16843655

Country of ref document: EP

Kind code of ref document: A1