WO2016165838A3 - Système de surveillance optique et capteur associé - Google Patents

Système de surveillance optique et capteur associé Download PDF

Info

Publication number
WO2016165838A3
WO2016165838A3 PCT/EP2016/025038 EP2016025038W WO2016165838A3 WO 2016165838 A3 WO2016165838 A3 WO 2016165838A3 EP 2016025038 W EP2016025038 W EP 2016025038W WO 2016165838 A3 WO2016165838 A3 WO 2016165838A3
Authority
WO
WIPO (PCT)
Prior art keywords
sensor
monitoring system
optical monitoring
sensor therefor
fluorescence
Prior art date
Application number
PCT/EP2016/025038
Other languages
English (en)
Other versions
WO2016165838A2 (fr
Inventor
John Julian DAVENPORT
Panayiotis Anastasios Kyriacou
Justin Phillips
Michelle Hickey
Original Assignee
The City University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The City University filed Critical The City University
Publication of WO2016165838A2 publication Critical patent/WO2016165838A2/fr
Publication of WO2016165838A3 publication Critical patent/WO2016165838A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14556—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004—Gaseous mixtures, e.g. polluted air
    • G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
    • G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
    • G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
    • G01N33/004—CO or CO2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432—Quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6434—Optrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7793—Sensor comprising plural indicators

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Combustion & Propulsion (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

La présente invention concerne un capteur optique comprenant des premier et second composants photosensibles qui sont chacun configurés de manière à être fluorescents, en réponse à une excitation par la lumière d'une première longueur d'onde, et à émettre de la lumière comprenant une deuxième et une troisième longueur d'onde respectivement ; la fluorescence dudit premier composant variant avec la concentration d'oxygène d'un milieu avec lequel le capteur est en contact, et la fluorescence dudit second composant variant avec la concentration de dioxyde de carbone d'un milieu avec lequel le capteur est en contact.
PCT/EP2016/025038 2015-04-14 2016-04-14 Système de surveillance optique et capteur associé WO2016165838A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1506332.4A GB201506332D0 (en) 2015-04-14 2015-04-14 Optical sensing system & sensor therefor
GB1506332.4 2015-04-14

Publications (2)

Publication Number Publication Date
WO2016165838A2 WO2016165838A2 (fr) 2016-10-20
WO2016165838A3 true WO2016165838A3 (fr) 2016-11-24

Family

ID=53333772

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2016/025038 WO2016165838A2 (fr) 2015-04-14 2016-04-14 Système de surveillance optique et capteur associé

Country Status (2)

Country Link
GB (2) GB201506332D0 (fr)
WO (1) WO2016165838A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107084967A (zh) * 2017-06-15 2017-08-22 福州普贝斯智能科技有限公司 一种水中溶解氧测量仪

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5152287A (en) * 1990-08-15 1992-10-06 Cordis Corporation Cross-linked fluorinated polymers for use in gas sensors
US20010034479A1 (en) * 2000-04-19 2001-10-25 Ring Lawrence S. Optically based transcutaneous blood gas sensor
US20110105869A1 (en) * 2006-01-04 2011-05-05 The Trustees Of The University Of Pennsylvania Sensor for Internal Monitoring of Tissue O2 and/or pH/CO2 In Vivo

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330718A (en) * 1989-08-16 1994-07-19 Puritan-Bennett Corporation Sensor element and method for making the same
US5747349A (en) * 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
WO2008133551A1 (fr) * 2007-04-27 2008-11-06 St. Jude Medical Ab Détecteur de concentration implantable et dispositif
JP2012503204A (ja) * 2008-09-19 2012-02-02 センサーズ・フォー・メデセン・アンド・サイエンス・インコーポレーテッド 光センサアセンブリ
CN202005754U (zh) * 2011-03-25 2011-10-12 复旦大学附属中山医院 可监测血液中溶氧分压和二氧化碳分压的荧光光纤传感器

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5152287A (en) * 1990-08-15 1992-10-06 Cordis Corporation Cross-linked fluorinated polymers for use in gas sensors
US20010034479A1 (en) * 2000-04-19 2001-10-25 Ring Lawrence S. Optically based transcutaneous blood gas sensor
US20110105869A1 (en) * 2006-01-04 2011-05-05 The Trustees Of The University Of Pennsylvania Sensor for Internal Monitoring of Tissue O2 and/or pH/CO2 In Vivo

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SERGEY M. BORISOV ET AL: "Modified Dual Lifetime Referencing Method for Simultaneous Optical Determination and Sensing of Two Analytes", APPLIED SPECTROSCOPY, vol. 60, no. 10, 1 October 2006 (2006-10-01), pages 1167 - 1173, XP055152735, ISSN: 0003-7028, DOI: 10.1366/000370206778664590 *

Also Published As

Publication number Publication date
GB2537504A (en) 2016-10-19
WO2016165838A2 (fr) 2016-10-20
GB201506332D0 (en) 2015-05-27

Similar Documents

Publication Publication Date Title
CL2016000679A1 (es) Sensor fluorométrico multicanal y método de uso del mismo
SG10201909423PA (en) Determination of water treatment parameters based on absorbance and fluorescence
WO2014106117A3 (fr) Systèmes de membrane perméables à des analytes pour une stabilité à l'oxydation et optique
BR112015022763A8 (pt) sensor para detectar um analito
MX2016016248A (es) Sistema para evitar bioensuciamiento.
WO2014176375A3 (fr) Systèmes et procédés d'enregistrement simultané d'une image en lumière visible et d'une image en lumière infrarouge à partir de fluorophores
WO2015044020A3 (fr) Système de moniteur d'absorption optique
EP2402736A3 (fr) Capteur de gaz "Cavity-Ring-Down" à longueur d'onde variable
EP2693198A3 (fr) Analyseur de gaz
WO2008137693A3 (fr) Cytométrie d'écoulement rétinien
EP4220158A3 (fr) Dispositif d'analyse d'échantillon d'urine et procédé d'analyse d'échantillon d'urine
SG10201809900PA (en) Hybrid Nanopore Sensors
GB201119334D0 (en) Improved ambient light sensing system and method
MX2017000881A (es) Pelicula intermedia para vidrio laminado, y vidrio laminado.
WO2014195917A3 (fr) Caractérisation d'échantillon basée sur un réseau
MX2019005697A (es) Medicion de longitud de onda secuencial multiple de una muestra liquida.
ES2568945T3 (es) Procedimiento para imponer un esquema de color dinámico en la luz de una unidad de iluminación
WO2013103441A3 (fr) Interrogateur à fibre multimode
WO2016165838A3 (fr) Système de surveillance optique et capteur associé
GB201117623D0 (en) Fluorescence gas and liquid sensor
EP2706324A3 (fr) Gyrolaser annulaire
EP2653920A3 (fr) Projecteur de source lumineuse laser
CL2018000146A1 (es) Dispositivo y sistema de medida óptica del coeficiente de reflexión de una superficie
WO2014046054A8 (fr) Dispositif de mesure de mouvement biologique et procédé de mesure de mouvement biologique
RU2016135524A (ru) Датчик кислорода, содержащий оптическое волокно большого диаметра с покрытым наконечником

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16732227

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 16732227

Country of ref document: EP

Kind code of ref document: A2