WO2016138713A1

WO2016138713A1 - Left ventricle volume reduction device

Info

Publication number: WO2016138713A1
Application number: PCT/CN2015/084024
Authority: WO
Inventors: 王超; 杨永森; 陈娟; 钱卫东; 罗鹏; 李博; 蒲忠杰
Original assignee: 上海形状记忆合金材料有限公司
Priority date: 2015-03-03
Filing date: 2015-07-15
Publication date: 2016-09-09
Also published as: CN104706444A; CN104706444B

Abstract

A left ventricle volume reduction device, comprising: a support frame (1) formed from a shape memory alloy, and a polymer membrane (2) covering the support frame (1); when the support frame (1) is released inside a left ventricle (3) from a cardiac apex (31) of the left ventricle (3), the shape of the support frame (1) after release fits to the inner wall of the left ventricle (3). An end of the support frame (1) away from the cardiac apex (31) is provided with a support end (11) extruding outward, and the support end (11) is attached on the inner wall of the left ventricle (3). An end of the support frame (1) close to the cardiac apex (31) is provided with a connection sleeve (5) detachably connected to a push rod (4). The left ventricle volume reduction device can isolate a non-functioning ventricle region of the left ventricle, reduce diastolic and systolic volume and left ventricle tension, and improve left ventricle reconstruction and cardiac function of a patient with heart failure. The device adopts an intervention path and provides a minimally invasive trans-cardiac apex (31) design to reduce trauma to minimum. The design reduces a diameter of a delivery sheath tube (9) in the trans-cardiac apex (31) path or an intervention path, avoiding the risk of damage to blood vessel and heart valves. The present invention adopts designs such as a locating base (6) and a cardiac apex locator (7), has a good locating function and strong fitting tension.

Description

Left ventricular volume reduction device

Technical field

The invention relates to a left ventricular volume reduction device.

Background technique

Heart failure is the ultimate destination of most cardiovascular diseases and the leading cause of death, with nearly 23 million people worldwide suffering from the disease. Parachute was the first percutaneous left ventricular reconstruction device based on catheter technology. The technology was first reported in 2007 and has been gradually developed abroad. It has accumulated hundreds of experiences and obtained European CE certification in 2011. It can effectively alleviate the clinical symptoms of patients with heart failure, improve heart function, and increase the five-year survival rate of patients with advanced heart failure from 30% to 80%. Currently, it has been applied in more than 500 cases in Europe and America.

The prevalence of heart failure in China is 0.9%, 1.4% in the northern region, and there are about 4 million heart failure patients. It is estimated that the incidence of acute myocardial infarction in China is about 45/100,000 to 55/100,000, and it is still on the rise.

In general, heart failure, especially in the chronic process, has a heart enlargement, with left ventricular enlargement, the patient's quality of life is significantly reduced, and the clinical prognosis is poor, resulting in a huge medical and social burden. Partial left ventriculectomy (PLV) is a surgical procedure for the treatment of advanced dilated cardiomyopathy in recent years, first proposed by Brazilian physician Batista in 1996. Left ventricular volume reduction surgery is also called "partial left ventricular resection" or "reserved left ventricular resection" in China, but left ventricular volume reduction surgery has higher heart failure, arrhythmia-related mortality, and limits It is widely used in clinical practice.

Percutaneous ventricular restoration (PVR) is a new approach to the treatment of heart failure symptoms. It is a leading-edge treatment for patients with old-fashioned anterior wall myocardial infarction and heart failure, in the heart of patients through minimally invasive intervention. The implantation of a "parachute" (CardioKinetix Parachute) has effectively improved the clinical symptoms of patients with heart failure. After a heart attack, many left heart patients have left ventricular dilatation leading to a decrease in cardiac output, resulting in heart failure symptoms such as shortness of breath. Ischemic heart disease can cause heart failure symptoms, ie left ventricular dysfunction. After the parachute is implanted, the parachute separates the damaged muscles and isolates the dysfunctional muscles from the normal part, thus reducing the overall heart volume and Restore more normal left ventricular function. The indications for percutaneous ventricular remodeling are old anterior wall myocardial infarction with no anterior wall motion or abnormal movement, and decreased left ventricular ejection fraction. Surgery for more than 70 minutes requires half anesthesia. Ultrasound and cardiac CT are used before surgery. For the size of the ventricle, choose the appropriate "parachute".

However, Parachute also has shortcomings and great operational difficulties: 1. The implanted device is mainly supported by support. The end of the end is placed in the inner wall of the heart, and thus the diameter is large, resulting in a large diameter of the delivery system, thereby causing the risk of the interventional pathway entering the human blood vessel and the heart to damage the blood vessel and the heart valve; 2. The resistance of the aortic valve to the implanted instrument is passed. Difficulty, high surgical complexity, long operation time, greatly increase the risk of surgery and reduce the success rate of surgery; 3, the positioning of the device and the tension of the fitting requirements are high, so the balloon expansion is required to release the shape.

Summary of the invention

In view of the above-mentioned shortcomings of the prior art, an object of the present invention is to provide a left ventricular volume reduction device for solving the problems of high volume, high risk, low success rate, and the like in the prior art for percutaneous ventricular reconstruction. problem.

To achieve the above and other related objects, the present invention provides a left ventricular volume reduction device comprising a support frame made of a shape memory alloy, the support frame is covered with a polymer film; and the support frame is released from the apex of the left ventricle When the left ventricle is in the left ventricle, the shape of the support frame after release is adapted to the inner wall of the left ventricle, and the end of the support frame away from the apex is provided with an outwardly extending support end, and the support end is caught on the inner wall of the left ventricle, and the support frame is close to One end of the apex is provided with a connecting sleeve detachably connected to the push rod.

Preferably, the support frame is composed of a plurality of support bones, and the ends of the plurality of support bones close to the apex are merged together and connected with the connection sleeve, and the support bone extends away from the end of the apex protruding to the outside of the polymer film covering area to form a support end.

Further preferably, the support end of the support bone is a support bead which is curled outward and then curled inward, and the smooth section supporting the bead abuts against the inner wall of the left ventricle.

Further preferably, the end of the plurality of support bones near the apex forms a recess that is recessed away from the apex, and the connecting sleeve is located in the recess.

Further preferably, the support frame further comprises a woven mesh covering the support surface composed of a plurality of support bones, and the polymer film covers the woven mesh.

Preferably, the support frame is composed of a woven mesh, and the support end of the support frame is a plurality of support wires extending outward from an end of the woven mesh away from the apex.

Further preferably, the polymer film is coated on the inside or the outside of the woven mesh.

Preferably, the support frame is composed of a multi-layer woven mesh, and the polymer film is sandwiched between two adjacent woven meshes.

Preferably, the end of the support frame near the apex is further provided with a positioning seat. The positioning seat is woven by a shape memory alloy, and the positioning seat is evenly arranged along the circumferential direction of the support frame. After the positioning seat is released, the positioning seat is abutted on the inner wall of the left ventricle. .

Further preferably, the positioning seat is composed of a plurality of spheres, and the plurality of spheres are evenly arranged along the circumferential direction of the support frame.

Further preferably, the positioning seat is composed of a plurality of positioning brackets, one end of the positioning bracket is connected with one end of the supporting bracket close to the apex, and the other end of the positioning bracket is provided with a positioning curl which is rolled up and rolled inward, and the positioning curl is smoothed. Duan arrived at the left The inner wall of the ventricle, a plurality of positioning struts are evenly arranged along the circumferential direction of the support frame.

Preferably, the end of the support frame near the apex is provided with a apex locator passing through the apex, the end of the apex locator extending from the left ventricle is provided with a lower disc surface, the lower disc surface is fitted with the outer wall of the left ventricle, and the connecting sleeve is located on the lower disc surface The apex locator and the lower surface are woven from a shape memory alloy.

Further preferably, a polymer film is interposed in the lower surface.

Further preferably, the apex locator is located at one end of the left ventricle and is provided with an upper disc surface, the upper disc surface is adhered to the inner wall of the left ventricle, and the upper disc surface is woven by a shape memory alloy.

Further preferably, the end of the support frame close to the apex and the apex positioner are connected by adjusting the waist, the adjustment waist is woven by the shape memory alloy, and the adjustment waist is provided with at least one pleat, and when the waist is stretched, the pleat is pulled apart.

As described above, the left ventricular volume reduction device of the present invention has the following beneficial effects:

The left ventricular volume reduction device can isolate the ventricle region of the left ventricle without function, reduce the contraction and diastolic volume, reduce the left ventricular tension, improve the cardiac function of patients with left ventricular remodeling and heart failure; use the interventional approach and create minimally invasive surgery The design of the apex reduces the trauma to a minimum; reduces the design of the diameter of the delivery sheath through the apical or interventional approach, avoiding the risk of damaging the blood vessels and heart valves; the device is designed with a positioning seat, a apex locator, etc. Good and fit tension, so it does not need to be expanded by balloon during release; the complexity of surgery is greatly reduced, the operation time is shortened, the risk of surgery is greatly reduced, and the success rate of surgery is increased.

DRAWINGS

Figure 1 is a schematic view showing the process of implanting the left ventricle volume reduction device into the left ventricle of the present invention.

2 is a schematic view showing the structure of the first embodiment of the left ventricular volume reducing device shown in FIG. 1.

Figure 3 is a front elevational view of the left ventricular volume reduction device of Figure 2.

4 is a schematic view showing the structure of the left ventricular volume reducing device shown in FIG. 2 in the left ventricle.

Fig. 5 is a view showing the structure of a second embodiment of the left ventricular volume reducing device shown in Fig. 1.

Fig. 6 is a schematic view showing the structure of the left ventricular volume reducing device shown in Fig. 5 in the left ventricle.

Fig. 7 is a view showing the structure of a third embodiment of the left ventricular volume reducing device shown in Fig. 1.

FIG. 8 is a structural schematic view showing the left ventricular volume reducing device shown in FIG. 7 in the left ventricle.

Fig. 9 is a view showing the structure of a fourth embodiment of the left ventricular volume reducing device shown in Fig. 1.

Figure 10 is a schematic view showing the structure of the left ventricular volume reducing device shown in Figure 9 in the left ventricle.

Fig. 11 is a view showing the structure of a fifth embodiment of the left ventricular volume reducing device shown in Fig. 1.

Fig. 12 is a view showing the structure of a sixth embodiment of the left ventricular volume reducing device shown in Fig. 1.

Fig. 13 is a view showing the structure of the seventh embodiment of the left ventricular volume reducing device shown in Fig. 1 in the left ventricle.

Fig. 14 is a view showing the structure of the eighth embodiment of the left ventricular volume reducing device shown in Fig. 1 in the left ventricle.

Fig. 15 is a view showing the structure of a ninth embodiment of the left ventricular volume reducing device shown in Fig. 1.

Fig. 16 is a view showing the structure of the tenth embodiment of the left ventricular volume reducing device shown in Fig. 1 in the left ventricle.

Fig. 17 is a view showing the structure of the eleventh embodiment of the left ventricular volume reducing device shown in Fig. 1 in the left ventricle.

Component label description

1 support frame

11 support end

12 support bone

13 support curling

14 notches

15 woven mesh

16 support wire

2 polymer film

3 left ventricle

31 apex

4 push rod

5 connection sleeve

6 positioning seat

61 sphere

62 positioning support

63 positioning curling

7 apex locator

71 lower disk

72 upper surface

8 Adjusting the waist

81 folds

9 delivery sheath

detailed description

The embodiments of the present invention are described below by way of specific embodiments, and those skilled in the art can readily understand other advantages and functions of the present invention from the disclosure.

Please refer to Figure 1 to Figure 17. It should be understood that the structures, the proportions, the sizes, and the like, which are illustrated in the specification of the present specification, are only used to clarify the contents disclosed in the specification for understanding and reading by those skilled in the art, and are not intended to limit the implementation of the present invention. The conditions are limited, so it is not technically meaningful. Any modification of the structure, change of the proportional relationship or adjustment of the size should remain in the present invention without affecting the effects and the achievable purposes of the present invention. The disclosed technical content is within the scope of the disclosure. In the meantime, the terms "upper", "lower", "left", "right", "intermediate" and "one" as used in this specification are also for convenience of description, and are not intended to limit the present. The scope of the invention can be implemented, and the change or adjustment of the relative relationship is considered to be within the scope of the invention.

As shown in FIG. 1 to FIG. 17, the present invention provides a left ventricular volume reduction device comprising a support frame 1 made of a shape memory alloy, the support frame 1 is covered with a polymer film 2; and the support frame 1 is left. When the apex 31 of the ventricle 3 is released into the left ventricle 3, the released shape of the support frame 1 is adapted to the inner wall of the left ventricle 3, and the end of the support frame 1 away from the apex 31 is provided with an outwardly extending support end 11 for supporting The end 11 is stuck on the inner wall of the left ventricle 3, and the end of the support frame 1 near the apex 31 is provided with a connecting sleeve 5 detachably connected to the push rod 4. The polymer film 4 may be made of a material such as polyethylene terephthalate PET or expanded polytetrafluoroethylene ePTFT, and the support frame 1 is made of a nickel-titanium alloy; since the nickel-titanium alloy has superelasticity and shape. With the memory function, the entire volume reduction device can be adaptively deformed in the left ventricle 3.

As shown in Fig. 1, the left ventricular volume reduction device is connected to the push rod 4. In the initial state, the push rod 4 and the left ventricular volume reduction device are all located in the delivery sheath 9; then, the push rod 4 pushes the left ventricular volume reduction device to In the left ventricle 3, the support frame 1 and the polymer film 2 are released in a shape compatible with the inner wall of the left ventricle 3, and the support end 11 is caught on the inner wall of the left ventricle 3 to function as a left ventricular volume reducing device.

As shown in FIG. 2 to FIG. 11, the support frame 1 is composed of a plurality of support bones 12, and a plurality of support bones 12 are close to the apex. One ends of 31 are joined together and connected to the connecting sleeve 5, and one end of the supporting bone 12 extending away from the apex 31 to the outside of the covering area of the polymer film 2 forms a supporting end 11 which is caught on the inner wall of the left ventricle 3. The length at which the support bone 12 protrudes to the outside of the area covered by the polymer film 2 is preferably 1 to 3 mm.

As shown in Figs. 11, 13, and 14, the support end 11 of the support bone 12 is a support bead 13 which is turned outward and then curled inward, and the smooth section of the support bead 13 abuts against the inner wall of the left ventricle 3. The support bead 13 functions to support the left ventricle, and does not cause the tip to be inserted into the inner wall of the left ventricle 3 to cause damage, and can also be adjusted or automatically adjusted by the operator after the left ventricular volume reduction device is implanted. Best location.

As shown in FIGS. 2 to 4, one end of the plurality of support bones 12 near the apex 31 forms a notch 14 that is recessed away from the apex 31, and the coupling sleeve 5 is located in the notch 14.

As shown in FIGS. 12 to 14, the support frame 1 further includes a woven mesh 15 which is covered on a support surface composed of a plurality of support bones 12, and the polymer film 2 is covered on the woven mesh 15. The function of the woven mesh 15 is to maintain the flat surface morphology of the polymer film 2 between the support bones 12, reduce the occurrence of thrombus, and at the same time enhance the blood-blocking performance and the elastic properties of the entire device.

As shown in Fig. 15, the support frame 1 can be composed solely of a woven mesh 15, and the support end 11 of the support frame 1 is a plurality of support wires 16 projecting outward from the end of the woven mesh 15 away from the apex 31. At this time, the polymer film 2 can be covered on the inside or the outside of the woven mesh 15. By using the woven mesh 15 as the support frame 1 alone, the diameter of the volume reduction device when it is received into the delivery sheath 9 can be reduced, so that the delivery sheath 9 having a smaller diameter can be used, and the delivery sheath 9 can be reduced in the interventional route to the blood vessel and Damage to structures such as heart valves and chordae.

As shown in FIG. 16 to FIG. 17, the support frame 1 may also be composed of a double-layer or multi-layer woven mesh 15, and the polymer film 2 is sandwiched between two adjacent woven meshes 15, or may be covered inside the woven mesh 15 or Externally.

As shown in FIG. 5 to FIG. 8 and FIG. 13 , the end of the support frame 1 near the apex 31 is further provided with a positioning seat 6 which is woven by a shape memory alloy, and the positioning seat 6 is evenly arranged along the circumferential direction of the support frame 1 . After the positioning seat 6 is released, the positioning seat 6 abuts against the inner wall of the left ventricle 3. The positioning seat 6 functions to relatively fix the position of the volume reducing device in the left ventricle 3.

As shown in FIGS. 5 to 8, the positioning seat 6 is composed of a plurality of balls 61 which are uniformly arranged along the circumferential direction of the support frame 1.

As shown in FIG. 13, the positioning seat 6 is composed of a plurality of positioning brackets 62. One end of the positioning bracket 62 is connected to one end of the supporting frame 1 near the apex 31, and the other end of the positioning bracket 62 is provided with an outwardly turned and then rolled inwardly. The bead 63, the smooth section of the positioning bead 63 abuts against the inner wall of the left ventricle 3, and the plurality of positioning stays 62 are evenly arranged along the circumferential direction of the support frame 1.

As shown in FIG. 7 to FIG. 11 , FIG. 14 , and FIG. 16 to FIG. 17 , the support frame 1 is provided near one end of the apex 31 . The apex locator 7 of the apex 31, the end of the apex locator 7 extending out of the left ventricle 3 is provided with a lower disc surface 71, the lower disc surface 71 is in conformity with the outer wall of the left ventricle 3, and the connecting sleeve 5 is located on the lower disc surface 71, and the apex is positioned The lower surface 71 and the lower surface 71 are woven from a shape memory alloy. As shown in FIGS. 16 to 17, the polymer film 2 can be sandwiched in the lower disk surface 71.

As shown in FIGS. 9 to 11 and 14, the apex positioner 7 is located at one end of the left ventricle 3, and is provided with an upper disc surface 72. The upper disc surface 72 is fitted to the inner wall of the left ventricle 3, and the upper disc surface 72 is woven by a shape memory alloy. to make. The apex locator 7, the lower disc surface 71 and the upper disc surface 72 are used to fix the relative position between the support frame 1 and the apex 31.

As shown in FIGS. 16 to 17, the end of the support frame 1 near the apex 31 and the apex locator 7 are connected by an adjustment waist 8, and the adjustment waist 8 is woven by a shape memory alloy, and the adjustment waist 8 is provided with at least one pleat 81. When the waist 8 is adjusted to stretch, the pleats 81 are pulled apart. When the apex locator 7 is pulled, the pleats 81 of the adjustment waist 8 are stretched or wrinkled, and the distance between the apex locator 7 and the support frame 1 can be adjusted to suit the anatomy of different patients.

A first embodiment of the left ventricular volume reduction device is shown in FIGS. 2 to 4, wherein the support frame 1 is a support bone 12, and one end of the plurality of support bones 12 near the apex 31 forms a direction away from the apex 31. A recessed recess 14 in which the connecting sleeve 5 is located.

A second embodiment of the left ventricular volume reducing device is shown in FIGS. 5 to 6, wherein the support frame 1 is a support bone 12 and is provided with a positioning seat 6 composed of a plurality of balls 61.

A third embodiment of the left ventricular volume reducing device is shown in FIGS. 7 to 8, wherein the support frame 1 is a support bone 12, and is provided with a positioning seat 6 composed of a plurality of balls 61 and a lower plate surface 71. Apex locator 7.

A fourth embodiment of the left ventricular volume reducing device is shown in Figures 9 to 10, wherein the support frame 1 is a support bone 12 and is provided with a apex locator 7 having a lower disk surface 71 and an upper disk surface 72.

A fifth embodiment of the left ventricular volume reduction device is shown in FIG. 11 , wherein the support frame 1 is a support bone 12 , and the support end 11 of the support bone 12 is a support bead 13 and is provided with a lower plate surface 71 . The apex locator 7 of the upper disk surface 72.

A sixth embodiment of the left ventricular volume reduction device is shown in FIG. 12, wherein the support frame 1 is composed of a support bone 12 and a woven mesh 15.

A seventh embodiment of the left ventricular volume reduction device is shown in FIG. 13 , wherein the support frame 1 is composed of a support bone 12 and a woven mesh 15 , and the support end 11 is a support bead 13 and is provided with a plurality of positioning supports. 62 is composed of a positioning seat 6.

An eighth embodiment of the left ventricular volume reducing device is shown in Fig. 14, wherein the support frame 1 is composed of a support bone 12 and a woven mesh 15, the support end 11 is a support bead 13, and a lower plate surface 71 is provided. , the heart of the upper surface 72 Pointer locator 7.

A ninth embodiment of the left ventricular volume reducing device is shown in Fig. 15, wherein the support frame 1 is composed of a woven mesh 15 and the support end 11 is a support wire 16.

A tenth embodiment of the left ventricular volume reduction device is shown in Fig. 16, wherein the support frame 1 is composed of a double or multi-layer woven mesh 15, and is provided with a apex locator 7 with a lower disk surface 71 for apical positioning. An adjustment waist 8 is also provided between the device 7 and the support frame 1, and the adjustment waist portion 8 is provided with a pleat 81.

An eleventh embodiment of the left ventricular volume reducing device is shown in Fig. 17, wherein the support frame 1 is composed of a double or multi-layer woven mesh 15, and is provided with a apex locator 7 with a lower disk surface 71, a apex An adjustment waist 8 is further provided between the positioner 7 and the support frame 1, and the adjustment waist 8 is provided with two pleats 81.

In summary, the left ventricular volume reduction device of the present invention can isolate the ventricular region of the left ventricle without function, reduce the contraction and diastolic volume, reduce the left ventricular tension, and improve the cardiac function of patients with left ventricular remodeling and heart failure; And create minimally invasive transapical design to minimize trauma; reduce the design of the diameter of the delivery sheath through the apical or interventional approach to avoid the risk of damage to blood vessels and heart valves; the device uses a positioning seat, apex locator The design of the structure, positioning and tension is strong, so there is no need to use the balloon to expand and shape during release; the surgical complexity is greatly reduced, the operation time is shortened, the risk of surgery is greatly reduced, and the operation is successful. rate. Therefore, the present invention effectively overcomes various shortcomings in the prior art and has high industrial utilization value.

The above-described embodiments are merely illustrative of the principles of the invention and its effects, and are not intended to limit the invention. Modifications or variations of the above-described embodiments may be made by those skilled in the art without departing from the spirit and scope of the invention. Therefore, all equivalent modifications or changes made by those skilled in the art without departing from the spirit and scope of the invention will be covered by the appended claims.

Claims

A left ventricular volume reduction device, characterized in that it comprises a support frame (1) made of a shape memory alloy, the support frame (1) is covered with a polymer film (2); the support frame ( 1) When released from the apex (31) of the left ventricle (3) into the left ventricle (3), the shape of the support frame (1) after release is adapted to the inner wall of the left ventricle (3), the support frame ( 1) One end away from the apex (31) is provided with an outwardly projecting support end (11) which is caught on the inner wall of the left ventricle (3), which is close to the apex ( One end of 31) is provided with a connecting sleeve (5) detachably connected to the push rod (4).
The left ventricular volume reduction device according to claim 1, wherein the support frame (1) is composed of a plurality of support bones (12), and the plurality of support bones (12) are close to one end of the apex (31). The two are joined together and connected to the connecting sleeve (5), and the supporting bone (12) extends away from the apex (31) to an end of the outer surface of the polymer film (2) to form a supporting end (11).
The left ventricular volume reducing device according to claim 2, wherein the supporting end (11) of the supporting bone (12) is a supporting bead (13) which is curled outward and then curled inward, the supporting roll The smooth section of the side (13) abuts against the inner wall of the left ventricle (3).
The left ventricular volume reduction device according to claim 2, wherein the plurality of support bones (12) are adjacent to one end of the apex (31) to form a recess (14) recessed away from the apex (31). The connecting sleeve (5) is located in the recess (14).
The left ventricular volume reduction device according to claim 2, wherein the support frame (1) further comprises a woven mesh (15), and the woven mesh (15) covers the plurality of support bones (12) On the support surface of the composition, the polymer film (2) is covered on the woven mesh (15).
A left ventricular volume reducing device according to claim 1, wherein said support frame (1) is composed of a woven mesh (15), and said support end (11) of said support frame (1) is woven from said The mesh (15) is a plurality of support wires (16) extending outward from one end of the apex (31).
The left ventricular volume reducing device according to claim 6, wherein the polymer film (2) covers the inside or the outside of the woven mesh (15).
The left ventricular volume reduction device according to claim 1, wherein the support frame (1) is composed of a multilayer woven mesh (15), and the polymer film (2) is sandwiched between two adjacent woven meshes. Between (15).
The left ventricular volume reduction device according to claim 1, characterized in that: at one end of the support frame (1) near the apex (31), a positioning seat (6) is further provided, and the positioning seat (6) is shaped by a shape memory. Alloy weaving The positioning seat (6) is evenly arranged along the circumferential direction of the support frame (1). After the positioning seat (6) is released, the positioning seat (6) abuts against the inner wall of the left ventricle (3). .
The left ventricular volume reduction device according to claim 9, wherein the positioning seat (6) is composed of a plurality of spheres (61) along the support frame (1) The circumferential direction is evenly arranged.
The left ventricular volume reduction device according to claim 9, wherein the positioning seat (6) is composed of a plurality of positioning supports (62), one end of the positioning support (62) and the support frame (1) Attached to one end of the apex (31), the other end of the positioning bracket (62) is provided with a positioning bead (63) which is rolled up and then rolled inward, and the smooth section of the positioning bead (63) is The inner wall of the left ventricle (3), the plurality of positioning struts (62) are evenly arranged along the circumferential direction of the support frame (1).
The left ventricular volume reducing device according to claim 1, characterized in that: one end of the support frame (1) near the apex (31) is provided with a apex locator (7) passing through the apex (31), the apex One end of the positioner (7) extending out of the left ventricle (3) is provided with a lower disc surface (71), and the lower disc surface (71) is fitted to the outer wall of the left ventricle (3), and the connecting sleeve (5) Located on the lower disk surface (71), the apex locator (7) and the lower disk surface (71) are woven from a shape memory alloy.
The left ventricular volume reducing device according to claim 12, wherein a polymer film (2) is interposed in the lower disk surface (71).
The left ventricular volume reducing device according to claim 12, wherein an end of the apex locator (7) located in the left ventricle (3) is provided with an upper disk surface (72), and the upper disk surface (72) is The inner wall of the left ventricle (3) is fitted, and the upper disc surface (72) is woven from a shape memory alloy.
The left ventricular volume reduction device according to claim 12, characterized in that: the end of the support frame (1) close to the apex (31) and the apex positioner (7) are connected by an adjustment waist (8), The adjustment waist (8) is woven from a shape memory alloy, and the adjustment waist (8) is provided with at least one pleat (81) which is pulled apart when the adjustment waist (8) is stretched.