WO2016090389A1 - Gomme à mâcher décongestionnante - Google Patents

Gomme à mâcher décongestionnante Download PDF

Info

Publication number
WO2016090389A1
WO2016090389A1 PCT/ZA2015/050028 ZA2015050028W WO2016090389A1 WO 2016090389 A1 WO2016090389 A1 WO 2016090389A1 ZA 2015050028 W ZA2015050028 W ZA 2015050028W WO 2016090389 A1 WO2016090389 A1 WO 2016090389A1
Authority
WO
WIPO (PCT)
Prior art keywords
gum
decongestant
chewing gum
dose
chewing
Prior art date
Application number
PCT/ZA2015/050028
Other languages
English (en)
Inventor
Michael T. Rathogwa
Original Assignee
Rathogwa Michael T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rathogwa Michael T filed Critical Rathogwa Michael T
Publication of WO2016090389A1 publication Critical patent/WO2016090389A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/08—Chewing gum characterised by the composition containing organic or inorganic compounds of the chewing gum base
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums

Definitions

  • This invention relates to a chewing gum to help middle ear air pressure equalisation.
  • the inventor is aware that during elevation changes or other ambient pressure changes the air pressure in the middle ear equalises with the ambient pressure via the Eustachian tube. Normally this happens intermittently by contraction of the tensor veli palatini muscles during swallowing, for example.
  • chewing gum which includes a gum base mixed with a decongestant.
  • the gum may include food safe flavouring and/ or food safe colouring.
  • the decongestant may be one or more of decongestants selected from an Alpha-adrenergic agonist and/ or a decongestant.
  • the Decongestant may be selected from pseudoephedrine, phenylephrine and/ or phenylpropanolamine.
  • the decongestants may be micro encapsulated to mask the bitter taste of pseudoephedrine, for example and to improve the organoleptic properties and compressibility.
  • the gum may also include naturally derived decongestants like menthol or eucalyptol.
  • the gum may also include a mucolytic agent such as acetylcysteine.
  • the gum may also include flavourings and/ or sugars or sweeteners.
  • the gum base may include polyols. Each dose of the gum may include between 10 and 60 mg of pseudoephedrine.
  • Each dose of the gum may include between 10 and 20 mg of phenylephrine.
  • Each dose of the gum may include between 25 and 75 mg of phenylpropanolamine.
  • One dose of the gum may include:
  • Another dose of the gum may include:
  • a further dose of the gum may include:
  • a first example of a dose of the gum includes:
  • a second example of a dose of the gum includes: 1610 mg of Health in Gum® (HIG) Gum base;
  • a third example of a dose of the gum includes:
  • the decongestant of the first example is replaced with oxymetazoline and menthol in 50:50 weight relationship.
  • any of the previous formulations include a pharmacologically active amount of Acrivastine or loratidine as an antihistamine.
  • any of the previous formulations also include a pharmacologically active amount of a mucolytic agent selected from acetylcysteine.
  • sweetener, non-stick agent and glidant is mixed to homogenous mixture and the decongestant is added and again mixed to form a homogenous mixture.
  • the gum base is then added and again mixed to homogenous mixture.
  • Flavourants may also be mixed in with the gum base.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une gomme à mâcher destinée à soulager les maux d'oreilles liés à la pression. Cette gomme à mâcher comprend une base de gomme mélangée à un décongestionnant.
PCT/ZA2015/050028 2014-12-01 2015-11-30 Gomme à mâcher décongestionnante WO2016090389A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA201408788 2014-12-01
ZA2014/08788 2014-12-01

Publications (1)

Publication Number Publication Date
WO2016090389A1 true WO2016090389A1 (fr) 2016-06-09

Family

ID=56092612

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ZA2015/050028 WO2016090389A1 (fr) 2014-12-01 2015-11-30 Gomme à mâcher décongestionnante

Country Status (2)

Country Link
WO (1) WO2016090389A1 (fr)
ZA (1) ZA201508730B (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639368A (en) * 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
EP0371584A2 (fr) * 1988-10-28 1990-06-06 McNEIL-PPC, INC. Composition masquant le goût désagréable et méthodes pour sa préparation
WO2000056281A1 (fr) * 1999-03-22 2000-09-28 Atp Avant-Garde Technologies & Product Marketing & Licensing S.A. Composition pour gommes a macher a usage medical, procede de fabrication et presentation sous forme de dragees
WO2006063189A2 (fr) * 2004-12-10 2006-06-15 Novartis Ag Systeme d'administration de medicament a desintegration rapide
US20060127473A1 (en) * 2004-12-13 2006-06-15 Nichols William M Compositions and methods for stabilizing active pharmaceutical ingredients

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639368A (en) * 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
EP0371584A2 (fr) * 1988-10-28 1990-06-06 McNEIL-PPC, INC. Composition masquant le goût désagréable et méthodes pour sa préparation
WO2000056281A1 (fr) * 1999-03-22 2000-09-28 Atp Avant-Garde Technologies & Product Marketing & Licensing S.A. Composition pour gommes a macher a usage medical, procede de fabrication et presentation sous forme de dragees
WO2006063189A2 (fr) * 2004-12-10 2006-06-15 Novartis Ag Systeme d'administration de medicament a desintegration rapide
US20060127473A1 (en) * 2004-12-13 2006-06-15 Nichols William M Compositions and methods for stabilizing active pharmaceutical ingredients

Also Published As

Publication number Publication date
ZA201508730B (en) 2017-03-29

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