WO2016074641A8 - Nadh或其盐在制备治疗苯丙酮尿症药物或保健品的应用 - Google Patents
Nadh或其盐在制备治疗苯丙酮尿症药物或保健品的应用 Download PDFInfo
- Publication number
- WO2016074641A8 WO2016074641A8 PCT/CN2015/094502 CN2015094502W WO2016074641A8 WO 2016074641 A8 WO2016074641 A8 WO 2016074641A8 CN 2015094502 W CN2015094502 W CN 2015094502W WO 2016074641 A8 WO2016074641 A8 WO 2016074641A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nadh
- salt
- health care
- care product
- preparing drug
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- 201000011252 Phenylketonuria Diseases 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 3
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 abstract 3
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
烟酰胺腺嘌呤二核苷酸(NADH)或其盐在制备治疗苯丙酮尿症的药物或保健品中的应用,其中所述NADH或其盐的单剂量为1~100 mg。
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/311,790 US20170095500A1 (en) | 2014-11-14 | 2015-11-13 | Use of nadh or salt thereof in preparation of drugs or health-care products for treating phenylketonuria |
US15/618,934 US9950000B2 (en) | 2014-11-14 | 2017-06-09 | Use of NADH or salt thereof in preparation of drugs or health-care products for treating phenylketonuria |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410644152.5 | 2014-11-14 | ||
CN201410644152.5A CN104352513B (zh) | 2014-11-14 | 2014-11-14 | Nadh或盐在制备治疗苯丙酮尿症药物或保健品的应用 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US15/311,790 A-371-Of-International US20170095500A1 (en) | 2014-11-14 | 2015-11-13 | Use of nadh or salt thereof in preparation of drugs or health-care products for treating phenylketonuria |
US15/618,934 Continuation US9950000B2 (en) | 2014-11-14 | 2017-06-09 | Use of NADH or salt thereof in preparation of drugs or health-care products for treating phenylketonuria |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2016074641A1 WO2016074641A1 (zh) | 2016-05-19 |
WO2016074641A8 true WO2016074641A8 (zh) | 2016-10-20 |
Family
ID=52519886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2015/094502 WO2016074641A1 (zh) | 2014-11-14 | 2015-11-13 | Nadh或其盐在制备治疗苯丙酮尿症药物或保健品的应用 |
Country Status (3)
Country | Link |
---|---|
US (2) | US20170095500A1 (zh) |
CN (1) | CN104352513B (zh) |
WO (1) | WO2016074641A1 (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104352513B (zh) * | 2014-11-14 | 2017-04-05 | 邦泰生物工程(深圳)有限公司 | Nadh或盐在制备治疗苯丙酮尿症药物或保健品的应用 |
WO2019028877A1 (zh) * | 2017-08-11 | 2019-02-14 | 邦泰生物工程(深圳)有限公司 | 一种含有nadh和nadph的组合物及其应用 |
CN109893510A (zh) * | 2019-02-28 | 2019-06-18 | 合肥康诺药物开发有限公司 | 一种辅酶i肠溶片及其制备方法 |
CN110638826A (zh) * | 2019-10-09 | 2020-01-03 | 泓博元生命科技(深圳)有限公司 | Nadh和/或nmn在制备肌肉增强或抑制肌肉量下降的药物或保健品中的应用 |
CN110638827A (zh) * | 2019-10-17 | 2020-01-03 | 泓博元生命科技(深圳)有限公司 | Nadh及其盐在制备皮肤色素抑制剂中的应用 |
CN110664830A (zh) * | 2019-10-24 | 2020-01-10 | 泓博元生命科技(深圳)有限公司 | Nadh及其盐在制备防治咽炎的药物或保健品中的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101360421B (zh) * | 2005-11-18 | 2014-06-18 | 康乃尔研究基金会有限公司 | 烟酰核苷组合物及其使用方法 |
KR20120039121A (ko) * | 2010-10-15 | 2012-04-25 | 고려대학교 산학협력단 | Nadh를 유효성분으로 하는 근육 피로 회복 또는 근육강화용 조성물 및 그 방법 |
CN103462003A (zh) * | 2013-08-13 | 2013-12-25 | 甘肃华羚生物技术研究中心 | 苯丙酮尿症病患者专用特膳食品 |
CN104352513B (zh) * | 2014-11-14 | 2017-04-05 | 邦泰生物工程(深圳)有限公司 | Nadh或盐在制备治疗苯丙酮尿症药物或保健品的应用 |
-
2014
- 2014-11-14 CN CN201410644152.5A patent/CN104352513B/zh active Active
-
2015
- 2015-11-13 WO PCT/CN2015/094502 patent/WO2016074641A1/zh active Application Filing
- 2015-11-13 US US15/311,790 patent/US20170095500A1/en not_active Abandoned
-
2017
- 2017-06-09 US US15/618,934 patent/US9950000B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN104352513B (zh) | 2017-04-05 |
CN104352513A (zh) | 2015-02-18 |
WO2016074641A1 (zh) | 2016-05-19 |
US9950000B2 (en) | 2018-04-24 |
US20170304346A1 (en) | 2017-10-26 |
US20170095500A1 (en) | 2017-04-06 |
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