WO2016047365A1

WO2016047365A1 - Guidewire

Info

Publication number: WO2016047365A1
Application number: PCT/JP2015/074303
Authority: WO
Inventors: 豊田野; 泰直大谷
Original assignee: テルモ株式会社
Priority date: 2014-09-26
Filing date: 2015-08-27
Publication date: 2016-03-31

Abstract

A guidewire according to the present invention is provided with a core portion (2A) comprising an elongated body having flexibility, the core portion (2A) comprising a main body portion (3) formed at a base end side and a plate portion (5) formed at a tip side, characterized in that a first fragile portion (51) extending linearly and a second fragile portion (52) extending linearly and intersecting with the first fragile portion (51) are formed on one surface or both surfaces of the plate portion (5), and in that a plurality of first fragile portions (51) and second fragile portions (52) are formed in a lattice pattern.

Description

Guide wire

The present invention relates to a guide wire used for guiding a catheter into a body cavity, particularly into a blood vessel.

The guide wire can be used for treatment of a site where surgical operation is difficult such as PTCA (Percutaneous Transluminal Coronary Angioplasty), treatment for the purpose of minimally invasive to the human body, or cardiovascular angiography. It is used when guiding a catheter used for examinations into the blood vessel. PTCA is a treatment method for securing a blood flow path by dilating a stenotic site of a coronary artery with a balloon or the like.

In PTCA, the balloon catheter is guided to the stenosis site by inserting the guide wire to the vicinity of the stenosis site of the blood vessel with the tip of the guide wire protruding from the tip of the balloon catheter. At that time, the guide wire needs to select and pass through a meandering or branched blood vessel, a narrowed blood vessel, or the like. Therefore, the guide wire used for PTCA is required to have excellent flexibility (blood vessel followability) in order to follow the blood vessel shape and not damage the blood vessel wall.

In addition, in PTCA, in order to follow a guide wire that is bent and branched, tip shaping may be performed before the guide wire is inserted into the blood vessel. Specifically, a doctor or the like is bent with a finger into a predetermined shape (for example, J shape) with the distal end portion of the guide wire in accordance with the shape of a branch blood vessel or the like, and is shaped. Therefore, the guide wire is required to be able to easily shape the tip as described above.

Conventionally, as a guide wire used in PTCA, Patent Literature 1 has proposed a guide wire having the following configuration. The guide wire of Patent Document 1 includes a long core part and a coil installed so as to cover the tip side of the core part, and a plate height (plate thickness) of 2 at the tip side of the core part. It has the flat plate part formed with the board width more than double.

International Publication No. 2009/126656

In the guide wire of Patent Document 1, by providing a thin flat plate portion on the distal end side of the core portion, the distal end portion of the guide wire becomes flexible and safety and blood vessel followability can be expected to some extent. However, even a guide wire having such flexibility has not been sufficient in tip shapeability.

Therefore, the present invention has been developed to solve such a problem, and the problem is to provide a guide wire having excellent tip shapeability.

In order to solve the above-mentioned problems, a guide wire according to the present invention is a guide wire having a core portion made of a long flexible material, and the core portion is a main body formed on the base end side. And a flat plate portion formed on the front end side, a first weakened portion extending linearly on one or both surfaces of the flat plate portion, and a second extending linearly and intersecting the first weakened portion. A fragile portion is formed, and a plurality of the first fragile portions and the second fragile portions are formed in a lattice shape.

The guide wire according to the present invention is provided so as to cover the distal end side of the core portion, and includes a coil portion formed by forming a strand in a spiral shape, and the core portion and the coil portion are fixed on the distal end side. It is preferable. Moreover, it is preferable that the guide wire which concerns on this invention is equipped with the resin coating part which consists of a resin material formed so that the front end side of the said core part may be covered.

In the guide wire according to the present invention, the first fragile portion and the second fragile portion are oblique fragile portions formed in a direction inclined with respect to the plate width direction, and the first fragile portion is inclined. It is preferable that the direction and the inclination direction of the second fragile portion are opposite directions. In addition, the guide wire according to the present invention is a folded line portion produced when the first fragile portion and the second fragile portion are bent along the plate thickness direction of the flat plate portion and then returned to the flat plate state. Preferably there is.

According to the guide wire of the present invention, the core portion is provided with the flat plate portion on the distal end side of the core portion, and the plurality of first fragile portions and second fragile portions are formed in a lattice shape on the flat plate portion. Since the flexibility at the distal end side of the guide wire is improved, the flexibility at the distal end portion of the guide wire is improved. Moreover, since the flexibility at the distal end portion of the guide wire is improved, it is easy to shape the distal end portion of the guide wire in accordance with the shape of the branch blood vessel or the like.

According to the guide wire according to the present invention, the flexibility on the distal end side of the guide wire is improved and the distal end shaping is facilitated, so that the minute shaping intended by a doctor or the like can be achieved.

It is a fragmentary longitudinal cross-section which shows 1st Embodiment of the guide wire of this invention. It is a top view in the front end side of the core part of the guide wire shown in FIG. It is a side view which shows typically the method of forming a 1st weak part in the single side | surface (upper surface) of the flat plate part shown in FIG. It is a side view which shows typically the method of forming a 2nd weak part in the single side | surface (upper surface) of the flat plate part shown in FIG. FIG. 3 is an end view of the core portion taken along line AA shown in FIG. 2. FIG. 3 is an end view of the core portion taken along line BB shown in FIG. 2. It is a side view in the front end side of the core part which shows 2nd Embodiment of the guide wire of this invention. It is a side view which shows typically the method of forming a 1st weak part in the lower surface of the flat plate part shown in FIG. It is a side view which shows typically the method of forming a 2nd weak part in the lower surface of the flat plate part shown in FIG. It is a fragmentary longitudinal cross-section which shows 3rd Embodiment of the guide wire of this invention.

A first embodiment of the guide wire according to the present invention will be described in detail with reference to the drawings. In the present invention, the distal end side refers to the blood vessel insertion side of the guide wire, and the proximal end side refers to the side on which a doctor or the like operates the guide wire.

As shown in FIG. 1, a guide wire (hereinafter referred to as a wire) 1 is a long object including a core portion 2 A, and the core portion 2 A includes a main body portion 3 and a flat plate portion 5. The 1st weak part 51 and the 2nd weak part 52 are formed in the single side | surface (upper surface 5a). The total length of the wire 1 is not particularly limited, and is preferably 200 to 5000 mm, for example. Moreover, it is preferable that the wire 1 is provided with the coil part 6 installed so that the core part 2A may be covered, and the core part 2A and the coil part 6 are being fixed by the front end side. As a fixing method, it is preferable to fix with a fixing material (fixing part) 72 such as solder (brazing material) or adhesive, but the fixing part 72 may be formed by welding. Each configuration will be described below.

<Core part>
As shown in FIGS. 1 and 2, the core portion 2 A is made of a long object having flexibility. The core portion 2A is preferably made of an elastic metal material such as a Ni—Ti alloy or stainless steel in consideration of the flexibility and strength of the wire 1. The core portion 2A includes a main body portion 3, a transition portion 4, and a flat plate portion 5 in order from the proximal end side to the distal end side. The flat plate portion 5 includes a plurality of first fragile portions 51 and second portions. A fragile portion 52 is formed. The core part 2A may not include the transition part 4.

(Main body)
As shown in FIGS. 1 and 2, the main body 3 is composed of a rod-like (non-flat plate) long object. The shape of the cross section of the main body 3 (the YZ axis plane and the cross section perpendicular to the length direction) is preferably substantially circular (see FIG. 5). The main body 3 includes a large-diameter portion 31 having a constant outer diameter from the proximal end side toward the distal end side, a first taper portion 32 whose outer diameter gradually decreases toward the distal end side, and a constant outer diameter. It is preferable to include a middle diameter portion 33 having a second outer diameter, a second taper portion 34 whose outer diameter gradually decreases toward the distal end side, and a small diameter portion 35 having a constant outer diameter.

As the tapered portion formed between the portions having a constant outer diameter (between the large diameter portion 31 and the medium diameter portion 33 and between the medium diameter portion 33 and the small diameter portion 35), the first taper is used. Although two of the part 32 and the 2nd taper part 34 were described, the taper part is not limited to two, What is necessary is just to form at least 1 part. In addition, a large-diameter portion 36 having the same outer diameter as the large-diameter portion 31 but having a different constituent material may be joined to the large-diameter portion 31 by a joint portion (welded portion) 37. The method for joining the large-diameter portion 31 and the large-diameter portion 36 is not particularly defined, but includes friction welding, spot welding using a laser, butt resistance welding such as upset welding, joining with a tubular joining member, and the like. .

(Migration Department)
As shown in FIGS. 1 and 2, the transition portion 4 connects the main body portion 3 and the flat plate portion 5, and crosses a rectangle from a cross section (see FIG. 5) such as a circle from the proximal end side toward the distal end side. This is a portion that gradually changes to the surface (see FIG. 6). The length of the transition part 4 is preferably 1 to 20 mm. The transition portion 4 is preferably produced together with the flat plate portion 5 by pressing the distal end side of the rod-shaped main body portion 3, preferably the distal end side having a reduced diameter, with a mold or the like.

(Plate part)
As shown in FIGS. 1 and 2, the flat plate portion 5 has a rectangular cross section (in order to give the wire 1 (core portion 2 A) flexibility and facilitate the tip shape of the wire tip portion ( (See FIG. 6). The flat plate portion 5 preferably has a plate length of 1 to 30 mm, a plate width of 0.1 to 0.5 mm, and a plate thickness of 0.01 to 0.06 mm. Further, the plate width of the flat plate portion 5 may increase or decrease toward the front end side, and the plate thickness may increase or decrease toward the front end side. The flat plate portion 5 is fixed to the coil portion 6 with a fixing material (fixing portion) 72 or the like at the tip side. In addition, since the shape of the cross section of the flat plate part 5 is produced by pressing, both ends of the cross section are slightly rounded and become substantially rectangular. However, for convenience of explanation, rounding is omitted in FIG.

Further, on one surface (upper surface 5a) of the flat plate portion 5, a first fragile portion 51 that extends linearly and a second fragile portion 52 that extends linearly and intersects the first fragile portion are formed. The 1 weak part 51 and the 2nd weak part 52 are formed in the grid | lattice form. The intersection angle θ between the first fragile portion 51 and the second fragile portion 52 on the tip side is preferably 10 to 80 degrees. Moreover, although the linear 1st and 2nd

weak parts

51 and 52 are formed in linear form, you may form in the shape of a curve. Here, the upper surface 5a is a surface serving as an inner peripheral surface when the wire tip is curved.

The plurality of first and second

fragile portions

51 and 52 are fold line portions, groove portions, half slit portions, and the like, and are preferably fold line portions.
The 1st and 2nd

broken line parts

51 and 52 of upper surface 5a are produced by the following methods, for example. As shown in FIGS. 3 and 4, the flat plate portion 5 is bent in the plate thickness direction in a direction that is a bending direction when the wire is used, and specifically, the upper surface 5a is bent so as to be an inner peripheral surface of the bending. Thereafter, by returning to the flat plate state, linear creases are formed only on the upper surface 5a of the flat plate portion 5 having a large deformation amount, and the first and second

bent line portions

51 and 52 are produced. The plurality of first and second

fold line portions

51 and 52 may be formed after the production of the plurality of first fold line portions 51, or the second fold line portion 51 and the second fold line portion 51 may be manufactured. The production of the bent line portions 52 may be performed alternately.

Although not shown, the groove portion as the fragile portion is produced by, for example, pressing a mold having a mold surface on which a convex portion is formed onto the upper surface 5a of the flat plate portion 5. Moreover, the half slit part as a weak part is produced by forming the slit which does not penetrate to the upper surface 5a of the flat plate part 5 to the lower surface 5b by laser processing.

As shown in FIG. 2, the plurality of first and second

fragile portions

51 and 52 are oblique fragile portions formed in a direction inclined with respect to the plate width direction, and the first fragile portion 51 is inclined. It is preferable that the direction and the inclination direction of the second fragile portion 52 are opposite directions.

The inclination angles α and β of the plurality of first and second

fragile portions

51 and 52 are preferably 5 to 80 degrees. In addition, the inclination angles α and β of the plurality of first and second

fragile portions

51 and 52 are preferably the same angle from the base end side toward the tip end side, but may be increased or decreased. The inclination angle α and the inclination angle β may be the same angle or different angles.
Although not shown, one of the first fragile portion 51 and the second fragile portion 52 has an inclination angle α, β of 0 degrees (parallel to the plate width direction) or 90 degrees (parallel to the plate length direction). A certain weak part may be sufficient, and the inclination angle (alpha) of the 1st weak part 51 may be 0 degree | times, and the inclination angle (beta) of the 2nd weak part 52 may be 90 degree | times.

The distances T1 and T2 between the adjacent first and second

weak parts

51 and 52 are preferably 0.01 to 10 mm. The plurality of intervals T1 and T2 are preferably the same interval from the proximal end side toward the distal end side, but may be increased or decreased. Note that the interval T1 and the interval T2 may be the same interval or different intervals.

Although not shown in the drawing, the first and second weakened

portions

51, 52 are adjusted by adjusting the crossing angle θ, the inclination angles α, β, and the intervals T1, T2, and from the proximal side toward the distal side, the first The density of the second

fragile portions

51 and 52 may be dense or sparse. Moreover, although it is preferable that the 1st and 2nd

weak parts

51 and 52 are formed over the whole length direction of the flat plate part 5, as shown in FIG. 2, the base end part side, center part, or front-end | tip part side It may be formed in a part. Further, the first and second

fragile portions

51 and 52 may be formed not only in the flat plate portion 5 but also in the transition portion 4.

In the wire 1 of the present invention, as described above, the plurality of first and second

fragile portions

51 and 52 are formed in a lattice shape on one surface (upper surface 5a) of the flat plate portion 5, so that the flexibility of the flat plate portion 5 is achieved. And the flexibility at the tip of the wire 1 is also improved. And since the softness | flexibility of the front-end | tip part of the wire 1 improves, it becomes easy to shape the front-end | tip part of the wire 1 according to shapes, such as a branch blood vessel. As a result, in the wire 1 of the present invention, the tip shapeability is improved. In addition, by forming the first and second

fragile portions

51 and 52 on one side (upper surface 5a) of the flat plate portion 5, when shaping the tip of the wire 1, the upper surface 5a side is closer to the lower surface side 5b. Shape shaping becomes easy, and fine shape intended by a doctor or the like becomes possible.

<Coil part>
As shown in FIG. 1, the coil portion 6 is a coil that is installed so as to cover the distal end side of the core portion 2 A and is formed by forming a strand in a spiral shape. The coil may be a so-called densely wound coil in which adjacent strands are in contact with each other or a coil in which adjacent strands are separated from each other. Further, the coil portion 6 is fixed to the core portion 2A (flat plate portion 5) with a fixing material (fixing portion) 72 or the like at the tip side.

The material constituting the strand is not particularly defined, but is preferably a metal material such as stainless steel or Pt—Ni alloy. Further, the size of the coil portion 6 is not particularly defined and varies depending on the purpose of use of the wire 1. In the wire 1 used for PTCA, the coil portion 6 preferably has a coil outer diameter of 0.2 to 0.5 mm and a coil length of 10 to 1000 mm. The outer diameter of the coil is preferably the same diameter in the length direction of the wire 1, but may be decreased toward the distal end side of the wire 1.

The coil portion 6 may be a combination of two or more metal materials. For example, the coil portion 6 includes a first coil portion 61 made of a stainless steel wire on the proximal end side and a second coil portion made of a Pt—Ni alloy wire made of a radiopaque material on the distal end side. 62, and both the

coil parts

61 and 62 may be joined by welding, adhesion or the like at the boundary part 63 between the first coil part 61 and the second coil part 62. Thereby, the front end side of the wire 1 becomes easy to visually recognize under X-ray fluoroscopy.

Next, the modification of 1st Embodiment of the wire 1 of this invention is demonstrated.
As shown in FIG. 1, it is sufficient for the wire 1 to have the core portion 2A and the coil portion 6 fixed at one point on the tip side, but the core portion 2A and the coil portion 6 are fixed at a plurality of locations. It is preferable.

For example, as shown in FIG. 1, in the wire 1, the distal end side of the core portion 2 A (flat plate portion 5) and the distal end side of the coil portion 6 (second coil portion 62) are fixed by a fixing material (fixing portion) 72. The intermediate part of the core part 2A (the base end side of the transition part 4, the small diameter part 35, and the distal end side of the second taper part 34) and the intermediate part of the coil part 6 (boundary part 63) are fixed materials ( The fixed portion 73 is fixed, and the intermediate portion of the core portion 2A (the proximal end side of the medium diameter portion 33 and the distal end side of the first tapered portion 32) and the proximal end of the coil portion 6 (first coil portion 61). The side is fixed with a fixing material (fixing part) 71.

Here, the fixing materials (fixing portions) 71, 72, 73 are solder (brazing material), an adhesive, and the like. The fixing method of the core portion 2A and the coil portion 6 is not limited to the fixing material (fixing portion) 71, 72, 73 as described above, and the fixing

portions

71, 72, 73 may be formed by welding. Good.

As shown in FIG. 1, the wire 1 preferably includes a resin coating portion 8 formed so as to cover at least the surface of the coil portion 6 on the tip side.

Specifically, the resin coating portion 8 includes part or all of the surface of the wire, that is, the entire surface of the second coil portion 62, the coil portion 6 (the first coil portion 61, the boundary portion 63, and the second coil). It is preferable to cover the entire surface of the portion 62) or the entire surface of the proximal end portion of the coil portion 6 and the core portion 2A.

The resin coating portion 8 is preferably made of a resin material such as a fluorine-based resin, a maleic anhydride-based polymer substance, or polyurethane. The thickness of the resin coating portion 8 is preferably 0.001 to 0.05 mm. Since the wire 1 is covered with the resin coating portion 8 as described above, the friction resistance (sliding resistance) of the wire 1 is reduced, so that the operability in the blood vessel is improved.

Next, a second embodiment of the guide wire according to the present invention will be described.
The guide wire uses the core portion 2B (see FIG. 7) instead of the core portion 2A (see FIGS. 1 and 2) of the first embodiment, and not only one side (upper surface 5a) of the flat plate portion 5, A plurality of first and second

fragile portions

51 and 52 are formed in a lattice shape on both surfaces (upper surface 5a and lower surface 5b).
In addition, since it is the same as that of the structure of 1st Embodiment about matters other than the 1st and 2nd

weak parts

51 and 52 being formed in the lower surface 5b of the flat plate part 5, description is abbreviate | omitted.

As shown in FIG. 7, the first and second

fragile portions

51 and 52 of the lower surface 5b are preferably formed alternately with the first and second

fragile portions

51 and 52 of the upper surface 5a, but at the same position. It may be formed. The first and second

fragile portions

51, 52 on the lower surface 5b are the first and second

fragile portions

51, 52 whose crossing angle θ, inclination angles α, β and intervals T1, T2 (see FIG. 2) are the upper surface 5a. Are preferably the same, but may be different.

The first and second weakened

portions

51 and 52 of the lower surface 5b are fold line portions, groove portions, half-slit portions, etc., and are preferably fold line portions. The types of the first and second

fragile portions

51, 52 on the lower surface 5b are preferably the same as the first and second

fragile portions

51, 52 on the upper surface 5a, but may be different. That is, when the broken line portion is formed as the fragile portion on the upper surface 5a, the fragile portion of the lower surface 5b is preferably a broken line portion.

The first and second

bent line portions

51 and 52 of the lower surface 5b are produced by the following method, for example. As shown in FIGS. 8 and 9, the flat plate portion 5 having the first and second

bent line portions

51 and 52 formed on the upper surface 5a is in the plate thickness direction, but in the direction opposite to the bending direction when using the wire. Bending, specifically, the lower surface 5b is bent so as to be the inner peripheral surface of the bending. Thereafter, by returning to the flat plate state, a linear crease is formed only on the lower surface 5b of the flat plate portion 5 with a large amount of deformation, and the first and second

bent line portions

51 and 52 are produced. The first and second

fold line portions

51 and 52 on the lower surface 5b may be formed after the completion of the production of the plurality of first fold line portions 51. The production of the two folded lines 52 may be performed alternately. Moreover, you may produce the 1st and 2nd

broken line parts

51 and 52 of the lower surface 5b by performing alternately production of the 1st and 2nd

bent line parts

51 and 52 of the upper surface 5a and the lower surface 5b.

In the guide wire of the present invention, the plurality of first and second

fragile portions

51 and 52 are formed in a lattice shape on both surfaces (the upper surface 5a and the lower surface 5b) of the flat plate portion 5 as described above. Since the flexibility of the guide wire is further improved, the flexibility of the distal end portion of the guide wire is further improved, and the distal end shaping of the guide wire is further facilitated. Thereby, the fine shape which a doctor etc. intends becomes possible.

As a modification of the second embodiment of the guide wire of the present invention, as in the first embodiment, an example in which the core portion 2B and the coil portion 6 are fixed at a plurality of locations, the wire surface is a resin coating portion 8 Examples are covered.

Next, a third embodiment of the guide wire of the present invention will be described.
As shown in FIG. 10, the guide wire 1 includes a resin coating portion 9 instead of the coil portion 6 in the first embodiment including the core portion 2A. Moreover, although not shown in figure, the guide wire 1 may be provided with the resin coating | coated part 9 instead of the coil part 6 in 2nd Embodiment provided with the core part 2B (refer FIG. 7).
In addition, since the structure of 1st or 2nd embodiment other than the resin coating part 9 is the same as that of the above, the resin coating part 9 is demonstrated and description other than that is abbreviate | omitted.

The resin coating portion 9 is formed so as to cover the distal end side of the core portion 2A or the core portion 2B, and is made of a resin material. Examples of the resin material include a fluorine-based resin and polyurethane, and polyurethane is preferable. The resin coating portion 9 is preferably formed such that the tip side is thicker than the base side, and preferably 0.001 to 0.05 mm. Moreover, it is preferable that the resin coating | coated part 9 is formed in the front end side roundly.

By providing such a resin coating portion 9, when the guide wire 1 is used, damage to the blood vessel wall by the core portion 2A or the core portion 2B is suppressed, and thus safety is improved. Further, since the guide wire 1 has reduced frictional resistance (sliding resistance), the operability in the blood vessel is also improved.

Next, a method for using the guide wire of the present invention will be described taking PTCA as an example.
The tip of the guide wire is protruded from the tip of the guiding catheter, and in that state, the guide wire is inserted into the femoral artery by the Seldinger method, and inserted into the right coronary artery through the aorta, aortic arch, and right coronary artery opening. With the guiding catheter left at the opening of the right coronary artery, only the guide wire is advanced further in the right coronary artery to pass through the vascular stenosis, and stops at the position where the tip of the guide wire exceeds the vascular stenosis. . Thereby, the passage of the balloon catheter for expanding the stenosis is secured.

Next, the tip of the balloon catheter inserted from the proximal end side of the guide wire is protruded from the tip of the guiding catheter, further advanced along the guide wire, inserted into the right coronary artery from the right coronary artery opening, and the balloon Stop when the balloon of the catheter reaches the position of the vascular stenosis.

Next, a balloon expansion fluid is injected from the proximal end side of the balloon catheter, the balloon is expanded, and the vascular stenosis is expanded. By doing in this way, deposits, such as cholesterol deposited on the vascular stenosis, are physically expanded and the blood flow obstruction is eliminated.

¡Pull out the balloon expansion fluid from inside the balloon and deflate the balloon. Next, the balloon catheter is moved in the proximal direction together with the guide wire, and the balloon catheter, the guide wire and the guiding catheter are extracted from the blood vessel. Thus, the PTCA procedure is completed.

1 Guide wire (wire)
2A, 2B Core part 3 Body part 4 Transition part 5 Flat plate part 51 1st weak part (1st broken line part)
52 2nd weak part (2nd broken line part)
6 Coil part 8, 9 Resin coating part

Claims

A guide wire having a core portion made of a flexible long object,
The core portion includes a main body portion formed on the base end side, and a flat plate portion formed on the tip end side,
A first fragile portion extending linearly and a second fragile portion extending linearly and intersecting the first fragile portion are formed on one surface or both surfaces of the flat plate portion, and a plurality of the first fragile portions, The guide wire, wherein the second fragile portion is formed in a lattice shape.
The guide wire is provided so as to cover the distal end side of the core portion, and includes a coil portion formed by forming a strand in a spiral shape, and the core portion and the coil portion are fixed on the distal end side. The guide wire according to claim 1.
2. The guide wire according to claim 1, wherein the guide wire includes a resin coating portion made of a resin material so as to cover a distal end side of the core portion.
The first fragile portion and the second fragile portion are slanted fragile portions formed in a direction inclined with respect to the plate width direction, and the inclination direction of the first fragile portion and the second fragile portion are The guide wire according to any one of claims 1 to 3, wherein an inclination direction is an opposite direction.
The said 1st weak part and the said 2nd weak part are the fold line parts produced when the said flat plate part is bend | folded along a plate | board thickness direction, and is returned to a flat plate state after that. Guide wire as described.