WO2015119720A1 - Prothese protectrice - Google Patents

Prothese protectrice Download PDF

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Publication number
WO2015119720A1
WO2015119720A1 PCT/US2014/072220 US2014072220W WO2015119720A1 WO 2015119720 A1 WO2015119720 A1 WO 2015119720A1 US 2014072220 W US2014072220 W US 2014072220W WO 2015119720 A1 WO2015119720 A1 WO 2015119720A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
dental
dental form
mouthguard
user
Prior art date
Application number
PCT/US2014/072220
Other languages
English (en)
Inventor
Christopher W. Circo
Tony Schrager
Xinhua Li
Hootan Farhat
Noah Tremblay
Original Assignee
Battle Sports Science, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battle Sports Science, Llc filed Critical Battle Sports Science, Llc
Priority to EP14882099.6A priority Critical patent/EP3091956A4/fr
Priority to CA2936386A priority patent/CA2936386A1/fr
Publication of WO2015119720A1 publication Critical patent/WO2015119720A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A—HUMAN NECESSITIES
    • A63—SPORTS; GAMES; AMUSEMENTS
    • A63B—APPARATUS FOR PHYSICAL TRAINING, GYMNASTICS, SWIMMING, CLIMBING, OR FENCING; BALL GAMES; TRAINING EQUIPMENT
    • A63B71/00—Games or sports accessories not covered in groups A63B1/00 - A63B69/00
    • A63B71/08—Body-protectors for players or sportsmen, i.e. body-protecting accessories affording protection of body parts against blows or collisions
    • A63B71/085—Mouth or teeth protectors

Definitions

  • the present disclosure relates to a dental form comprising at least one first composition and at least one second composition that react when mixed to form a third composition in the dental form.
  • mouthguards prepared by reacting a first composition with at least one second composition to form a third composition in a dental form and kits comprising at least one first composition, at least one second composition, at least one dental form, and an optional external shell.
  • Mouthguards used for athletic activity are typically formed of plastic or rubber and engage a user's upper and lower teeth to keep the guard in position.
  • the mouthguard is imprinted with the wearer's tooth impression. This is commonly done in one of two ways.
  • One inexpensive mouthguard known as the "boil-and-bite" mouthguard, is partially custom fit by forming a mouthguard blank from a thermoplastic material that is softened at high temperatures and accepts the impression of the wearer's teeth while hot.
  • a fully custom- formed mouthguard may be obtained through one or more appointments with dentist or other dental professional. During the appointments, an impression of the wearer's teeth is molded into plaster. The resulting mold is sent to a manufacturer to produce a mouthguard with a permanent tooth pattern that ensures a sturdy fit in the wearer's mouth. Additional fit adjustments may be performed during follow-up appointments with the dental professional
  • Boil-and-bite mouthguards provide an inexpensive, easily formed mouthguard. However, they can be difficult to mold properly because of the properties of the material and the high temperature of the mouthguard when it is inserted for molding. This difficulty often leads to a poor fit for the mouthguard in the athlete's mouth. When the steps are performed incorrectly, the hot material can irritate and even burn the user's lips and gum tissue. Moreover, re-boiling the mouthguard can lead to permanent degradation in the performance of the mouthguard, making a miscasting a potentially costly mistake. Custom- formed mouthguards from a dental professional lack reasonable convenience for the casual athletic competitor; requiring one or more appointments to the dental professional's office.
  • dental forms comprising at least one first composition and at least one second composition that when mixed, react to form a third composition in the dental form.
  • the dental form may comprise an exterior dental shell that when inserted into the user's mouth, can either be discarded or remain adhered to the dental form.
  • the dental form is self-contained and does not have an exterior dental shell, but is encompassed, for instance, by a flexible membrane that is either rigid or pliant but allows the user to handle with ease.
  • the at least one first composition and the at least one second composition are at least partially separated prior to mixing by at least one physical barrier in the dental form.
  • the dental forms may comprise a plurality of compositions and physical barriers.
  • the dental form comprises a first composition at least partially separated from a second composition by a physical barrier.
  • the individual compositions may comprise reactive resin systems that react to form a solid final resin as the third composition.
  • the individual compositions comprise at least one indicator that when mixed, produce a new indicator to signal to the user to insert the dental form into the mouth.
  • kits comprising at least one first composition, at least one second composition, a dental form, and optionally at least one exterior dental shell.
  • the kits may comprise dental forms comprising the at least one first composition and the at least one second composition separated by at least one barrier.
  • the kits comprise at least one dental form that is subdivided by at least one barrier and is present in its pre-filled state, and separate compartments comprising the at least one first and second compositions.
  • Methods of using the dental forms and processes of preparing mouthguards are also disclosed. For example, the user can prepare a mouthguard by mechanically disrupting the physical barrier at least partially separating the at least one first and second compositions within the dental form, and allowing the mixed third composition to cure.
  • Figure 1(A) depicts a perspective view of one embodiment of a dental form according to the present disclosure.
  • Figure 1(B) depicts a cross-sectional view of one embodiment of a two-part composition dental form in the initial state before the two-part composition is mixed.
  • Figure 1(C) depicts the two-part composition dental form of Figure 1(B) after a rupturable membrane has opened, the two compositions have mixed to form a third composition and at least partially surrounded the user's teeth.
  • Figure 2(A) depicts a cross-sectional view of one embodiment of a two-part composition dental form in the initial state before the two-part composition is mixed to form a third composition, wherein a rupturable membrane covers at least one composition, such that a peripheral edge portion of the membrane is adhered to the base wall of an exterior dental shell.
  • Figure 2(B) depicts a cross-sectional view of another embodiment of a two-part composition dental form in the initial state before the two-part composition is mixed to form a third composition, wherein a rupturable membrane covers at least one composition, such that peripheral edge portions of the membrane are adhered to the opposing forward and rear walls of an exterior dental shell.
  • Figure 2(C) depicts a cross-sectional view of another embodiment of a two-part composition in the initial state before the two-part composition is mixed to form a third composition, wherein a rupturable membrane substantially envelopes at least one first composition in a separate packet that resides within at least one second composition.
  • Figure 3 depicts a perspective view of a multiple two-part composition dental form, wherein a series of successive composition chambers are positioned within a mold channel of an exterior dental shell, separated by individual membrane dividers, in an initial state before the two-part compositions are mixed.
  • Figure 4 demonstrates (A) a dental form detached from an exterior dental shell comprising two compositions separated by at least one rupturable membrane; (B) that dental form within a mold channel of an exterior dental shell in an initial state before the two compositions are mixed; (C) two-part composition dental form of Figure 4(B) after a rupturable membrane has opened, the two compositions have mixed to form a third composition and at least partially surrounded the user's teeth; and (D) removal of the finished mouthguard after the compositions have mixed and are at least partially cured.
  • Figure 5 demonstrates a cross-sectional view of another embodiment wherein the dental form has varied thickness levels at different portions of the dental form.
  • Figure 6 demonstrates a cross-sectional view of a dental form comprising reinforcement elements embedded into the dental form.
  • Figure 7 demonstrates a cross-sectional view of a dental form comprising a mechanical clip.
  • Figure 8 demonstrates a dental form comprising a mechanical clip separating two compositions.
  • Figure 9 demonstrates a dental form for the top and bottom arcade of teeth where the top of the dental form extends upward to receive the user's top teeth and the bottom of the dental form extends downward and is open to receive the user's bottom teeth.
  • Figure 10(A) demonstrates a kit comprising: a top cover, a bottom cover comprising a port opening, a packet comprising a first composition, and a plug.
  • Figure 10(B) demonstrates how the pieces of the kit are manufactured to produce a mouthguard: an adhesive is applied to the rims of the bottom cover and the area in the bottom of the cover where the packet will sit. The packet and the top cover are adhered to the sections containing the adhesive. A second composition is injected into the port opening of the bottom cover and a plug comprising an adhesive is inserted into the port opening to seal the port opening.
  • the term "about,” when used in connection with a specific value, means that acceptable deviations from that value are also encompassed.
  • the term “about” means that a value higher or lower than the given value by 1%, 3%, 5% 10%, 15%, 20%, 25%, 30%, 35% or 40% is encompassed.
  • the value higher or lower than the given value may range from 5% to 40%, such as from 10% to 35% or from 10% to 20%.
  • the given value may range higher or lower by 20%, 10%, or 5%.
  • the at least one dental form comprises at least one first composition and at least one second composition that when mixed, react to form a third composition in the dental form.
  • the dental forms according to the present disclosure may directly adhere to an exterior dental shell or they may be self-contained without the need for an exterior dental shell.
  • the dental form may further comprise a flexible membrane encompassing the at least one first composition and the at least one second composition.
  • the flexible membrane comprises, for example, but is not limited to silicone rubbers such as DUROPRENE, or the silicone rubbers sold under the trade name DRAGON SKIN, such as DRAGON SKIN 10, by Smooth-On, or the resin material sold under the trade name BLUESIL, such as BLUESIL 3040, by Bluestar Silicones; polyurethanes; polycaprolactones, synthetic rubbers; and nylon.
  • the flexible membrane is either rigid or pliant but must be sufficiently flexible with a proper tensile strength that it will not rupture under the pressure of the user's teeth, but will flex and allow the encased compositions to surround the user's teeth and gum line.
  • the flexible membrane may have a thickness ranging from about .0005 inches to about .005 inches.
  • the dental form will have a shape that may vary according to the intended use and the shape and of the intended user's mouth. However, various embodiments of the dental form will be arcuately shaped to fill a mold channel of an exterior dental shell, defined by a base wall 16, a forward wall 18 and a rear wall 20. The forward wall 18 and rear wall 20 extend outwardly from the base wall 16 in a spaced apart, generally parallel relationship with one another. Accordingly, in at least one embodiment, the mold channel 14 is shaped to receive an upper arcade of a user's teeth, such as shown in Figure 1(A), and in another embodiment, may be shaped to receive a lower arcade of a user's teeth, such as shown in Figure 9.
  • the dental form may have a consistent thickness level throughout the dental form, or may have varied levels of thickness, for instance, have a thicker walls in areas requiring greater rigidity.
  • the dental form has a thickness of less than or equal to about 2 mm in at least one section of the dental form.
  • the dental forms of the present disclosure may further comprise at least one reinforcement element, and in at least one embodiment, may comprise a plurality of reinforcement elements.
  • reinforcement element is understood to mean a rigid structural component to reinforce the dental form as needed, for example, to provide an arcuately shaped form, or, for instance, to anchor the dental form to an exterior dental shell.
  • Non-limiting examples of the at least one reinforcement element include thermoplastic materials known to those skilled in the art.
  • the dental forms may have a Shore A hardness less than or equal to about 30, for instance, less than about 25.
  • the exterior dental shell may comprise a durable, rigid plastic that is easily moldable during fabrication.
  • exemplary materials that may be used to construct the exterior dental shell include: poly(ethylene-co-vinyl acetate) (EVA); PMMA; PolyHEMA; and other polymers of like properties.
  • EVA poly(ethylene-co-vinyl acetate)
  • PMMA poly(ethylene-co-vinyl acetate)
  • PolyHEMA poly(ethylene-co-vinyl acetate)
  • Other rigid materials are contemplated, depending on the intended use of the dental forms including various metals, rubbers, and the like.
  • the dental forms of the present disclosure may comprise multiple compositions but at a minimum, comprise at least one first composition and at least one second composition that react when mixed to form a third composition.
  • the at least one first and second compositions comprise the same components.
  • the at least one first and second compositions comprise different components.
  • compositions disclosed herein may be present in the dental forms in different proportions.
  • the at least one first composition may be present in an amount ranging from about 1% to about 99% and the at least one second composition may be present in an amount ranging from about 99% to about 1%.
  • the at least one first composition and the at least one second composition are present in the same proportion, i.e., 50%.
  • compositions may comprise at least one reactant component, for instance, reactive resins systems that react to form a solid, final resin. Selection of the resin components will vary dependent upon the intended use of the dental forms taking into consideration parameters such as cure times, strength, weight, cost, shelf life, and the like.
  • the dental forms comprise compositions comprising FDA-approved components.
  • Reactive resin systems typically contain two liquid or powder components that react to create a solid, final resin. There are two predominant hardening mechanisms: reactive monomer/catalyst, and polymer/crosslinker.
  • the polymerization reaction converts the liquid monomer into a hard polymer.
  • An example (non-FDA- approvable) of this type of reaction is the production of epoxy -based resins.
  • the crosslinker is a polymer or small molecule that converts a liquid or soluble linear polymer into a solid or insoluble crosslinked polymer.
  • An example of the second mode of reactivity is the production of various polyurethane resins, such as the products sold under the trade name SMOOTH-CAST.
  • the at least one first composition comprises about 10 mL of SMOOTH-CAST 300Q and the at least one second composition comprises about 10 mL of SMOOTH-CAST 300Q.
  • non-biocompatible materials could be used with the present technology and achieve desirable mechanical attributes for the resulting mouthguards.
  • non-biocompatible materials include, but are not limited to, two-part organic resins such as two-part epoxies, two-part polyurethanes, and two-part polyureas.
  • Acrylic polymer systems may be used, where the first composition of the system is an acrylic formulation containing reactive monomers and the second composition contains initiator or activator. Specific examples of such a system include methyl methacrylate,
  • Silicone based materials may be used, such as silicone prepolymers that can be cured in situ.
  • the polymer can be cured by water, for instance, the at least one first composition comprises about 20 mL water and the at least one second composition comprises about 4 mL of ALJA-SAFE BREEZE.
  • silicones can be rapidly cured by catalyized hydrosilalation reaction. It is contemplated that some embodiments could use polymer systems using click chemistry/fast crosslinking reactions.
  • biocompatible polymers including polyurethane, silicone and polyethylene glycol, polysaccharide and polycaprolactone can be functionalized with reactive groups including thiol, aclyrate, malimide, alkyne, and azide.
  • thiol is used to functionalize the prepolymer.
  • the prepolymer can be rapidly crosslinked with a multi-acrylate crosslinker in the presence of a catalyst (e.g. an amine, or a phosphine).
  • the thiol functionalized prepolymer can be crosslinked with malimide containing crosslinker.
  • one prepolymer is modified with alkyne and the other prepolymer is modified with azide. The azide and alkyne modified polymers crosslink in the presence of a catalyst.
  • the multi-part resin may comprise biocompatible materials, for instance, the products sold under the trade name SUPERPASTE, by Bosworth Company.
  • cement is used.
  • the first composition comprises metal, semi-metal oxides or metal salts and the second composition comprises water.
  • Specific examples include calcium oxide and water, calcium phosphate and water, and zinc oxide/eugenol and water.
  • Most common cements are non-toxic and are already widely used in dental care; they are created by mixing water with metal or semi-metal oxides.
  • the most familiar type of cement comprises mostly calcium oxide, but there are many different metal oxides and semi-metal oxides (i.e., silicon dioxide) that undergo cement gelation and would be viable options for investigation.
  • Cement gelation proceeds via a mechanism in which water acts as a crosslinker to bridge metal or semi-metal atoms.
  • the resin is formed using metal-ion-crosslinked polymers.
  • the first composition comprises a polyol or polysaccharide and the second composition is an aqueous solution of a multivalentmetal ion such as calcium, zinc, magnesium, aluminum, etc.
  • a specific example is where the first composition is a solution of sodium alginate and the second composition is an aqueous solution of calcium chloride.
  • the resin are formed using traditional gels.
  • the first composition comprises a polyol, protein, or other water soluble or dispersible polymer and the second composition comprises water.
  • gelatin and water Some embodiments of the resin may be formed using swellable hydrogels.
  • the first composition is a crosslinked hydrogel and the second composition is water.
  • the second composition is water.
  • One specific example of this is partially crosslinked sodium polyacrylate and water.
  • Other embodiments of the resin may be formed using a borate crosslinked polymer system.
  • the first composition is polymer containing amines or hydroxyl-groups and the second composition is boric acid or a boric ester.
  • One specific example is polyvinyl alcohol aqueous solution and sodium borate aqueous solution.
  • Still other embodiments of the resin may be formed using clays crosslinked with a biocompatible polymer.
  • the first composition is a clay particle or a clay particle suspension in water and the second composition is a polycation or a polyanion.
  • One specific example is negatively charged montmorillonite and poly lysine.
  • Another embodiment of the resin may be formed using a protein/peptide based formulation where the first composition is a protein or peptide solution and the second composition is a pH modifier.
  • One example is fibrinogen and thrombin.
  • Another example is a carboxylate-containing protein crosslinked by calcium ions.
  • Metal-ion-crosslinking materials work very differently.
  • water soluble polymers such as sodium alginate
  • a solution of different metal salts is mixed with the water-soluble polymer.
  • the metal ions become bound by hydrophilic functional groups on the polymers, effectively cross-linking the polymer in solution.
  • the polymer retains the water and becomes a hydrogel.
  • pre-crosslinked hydrogels can be dehydrated and then re-swollen with water to form an expanding solid gel.
  • water could be mixed with hydrogels, like the metal-ion crosslinked type, and solid particles would absorb and swell with water to form a dense material.
  • fillers can be added to the compositions disclosed herein to attain the desired mechanical properties.
  • fillers is understood to mean a material that is mixed into the resins or cements, but does not take part in any chemical reaction.
  • Non-limiting examples of fillers include metal oxide particles, polymer fibers, silica powders, and mixtures thereof.
  • fillers may be added to impart higher tear strength, for example, cellulose fibers, polymer fibers, carbon fibers, clay, silica, calcium carbonate, calcium phosphate, zinc oxide, and combinations thereof.
  • compositions disclosed herein may comprise active agents, lubricants, surfactants, binders, flavoring agents, and combinations thereof, depending on the preference of the manufacturer of the dental forms.
  • the compositions may further comprise at least one indicator.
  • the compositions may each comprise different indicators that when mixed create a new indicator.
  • the indicators may be chosen from those known to one of ordinary skill in the art. Non-limiting examples include visual indicators, such as color and luminescent indicators, such as color dyes, organic acids, low pH indicators, metal salts and complementary ligands thereof, light absorbing molecules, fluorescent and
  • phosphorescent emitting molecules phosphorescent emitting molecules, chemiluminescent molecules, and combinations thereof.
  • the at least one first composition comprises one indicator, for instance, a blue dye, and the at least one second composition comprises a different indicator, for instance, a yellow dye, that when mixed, forms a third color, for instance, a green color in the third composition.
  • the at least one first composition comprises an organic acid indicator and the at least one second composition comprises a low pH indicator, that when mixed, forms a colored salt in the third composition.
  • the at least one first composition comprises an indicator chosen from metal salts, and the at least one second composition comprises a ligand complementary to the metal salt, that when mixed, forms a colored metal complex in the third composition.
  • the at least one first composition comprises one indicator chosen from efficient light absorbing molecules
  • the at least one second composition comprises an indicator chosen from efficient fluorescent and phosphorescent emitting molecules, that when mixed, forms a new overall fluorescent and/or phosphorescent emission spectrum via fluorescence resonance energy transfer (FRET).
  • the at least one first composition comprises one indicator chosen from chemiluminescent molecules, such as luminol
  • the at least one second composition comprises an indicator chosen from oxidizing agents, such as organic peroxide, that when mixed, produces a luminescent third composition.
  • the at least one first composition and the at least one second composition may be separated in the dental form by the presence of at least one physical barrier.
  • the term "separated" is understood to mean that, at a minimum, the at least one first composition and the at least second composition are at least partially separated. However, in at least one embodiment, the at least one first composition and the at least one second composition are completely separated by at least one physical barrier.
  • the at least one physical barrier may be a rupturable membrane 24, flexible membrane 28, or may be a naturally-formed interface present between the at least first composition and the at least second composition.
  • the at least one physical barrier is a rupturable membrane 28.
  • the at least one rupturable membrane may have a lower tear resistance than the at least one flexible membrane.
  • Non-limiting examples of the rupturable membrane include polyesters, polycarbonate epoxies, acrylic polymers, carbohydrates, chitin, chitosan, polystyrenes, polyethylenes, polypropylenes, hydrophobic fiber mat, paper, non-woven polymer films, and combinations thereof.
  • the at least one physical barrier is a flexible membrane 24.
  • the flexible membrane of the dental form is compressed, for instance, in the middle of the dental form, to form a subdivided dental form.
  • the dental form may be twisted or pinched to create the physical separation of the at least first and second compositions. The compression of the flexible membrane forces at least two sections of the flexible membrane to touch, thus producing a physical barrier to separate the at least one first composition and the at least one second composition.
  • the compressed dental form is held in place by at least one mechanical clip.
  • a user may utilize the at least one mechanical clip to compress the dental form to at least partially separate the at least one first and second compositions.
  • the at least one physical barrier is formed at the interface between the at least one first composition and the at least one second composition.
  • the at least one first and the at least one second composition naturally form an interface that at least partially separates the compositions.
  • kits comprise at least one first composition, at least one second composition, at least one dental form, and at least one optional exterior dental shell.
  • the kits may be used to prepare mouthguards, for instance, the kit may comprise at least one dental form filled with the at least one first composition and the at least one second composition at least partially separated by at least one barrier in the dental form, or the kits may comprise at least one dental form subdivided but present in a pre-filled state, with other components of the kits comprising the at least one first and second compositions.
  • the kits may further comprise instructions for application and use.
  • the kits comprise at least one dental form comprising at least one first composition at least partially separated by at least one second composition, an exterior dental shell, and instructions for use.
  • kits may comprise a separate mechanical clip that the user applies to the dental form to subdivide the dental form prior to insertion of the at least one first and second compositions.
  • a kit may comprise a top cover of a mouthguard, a bottom cover of a mouthguard comprising a port opening, at least one first composition within a packet and a plug.
  • kits disclosed herein may further comprise at least one second composition, at least one adhesive, and at least one syringe.
  • the at least one second composition may be encapsulated in a separate packet from the at least one first composition.
  • an adhesive is applied to the rims and inside the bottom cover and the packet comprising a first composition and the top cover are adhered to the sections containing the resin.
  • At least one second composition is injected into the port opening of the bottom cover, and a plug comprising adhesive is inserted into the port opening to seal the port opening.
  • the adhesive in the kits according to the present disclosure may be chosen from adhesives known to one of ordinary skill in the art, for example standard silicone.
  • the packets comprising the compositions may also be chosen from standard plastics known to one of ordinary skill in the art, for instance, polyethylene and polystyrene.
  • the packets may be metallized, for example, with at least one side of the packet comprising at least one metal, such as aluminum.
  • Mouthguards may be prepared by processes according to the present disclosure.
  • the mouthguard may be prepared by contacting at least one first composition with at least one second composition to form a third composition.
  • the at least one first and second compositions are at least partially separated prior to mixing.
  • the third composition begins to cure for a period of time until substantially cured, for example, from about 10 seconds to about 10 minutes, such as from about 1 minute to about 5 minutes, for instance, from about 2 minutes to about 3 minutes. In at least one embodiment, the cure time is about 5 minutes.
  • the curing third composition is adhered to the user's upper arcade of teeth or lower arcade of teeth until the curing time is substantially completed, at which time the user can remove the dental form and use the mouthguard.
  • the resulting mouthguard can either be the cured third composition itself, which can be removed from the dental form, or can remain attached to the dental form, optionally adhered to an exterior dental shell.
  • the mouthguard is prepared by
  • the user may insert the dental form into the user's mouth such that the upper arcade of teeth or lower arcade of teeth are received within the mold channel of the dental form.
  • the user ruptures the at least one physical barrier in the dental form by biting down on the dental form.
  • the user ruptures the at least one physical barrier in the dental form by pinching the dental form prior to insertion into the user's mouth.
  • the user ruptures the at least one physical barrier by removing a mechanical clip from the dental form prior to insertion into the user's mouth. Regardless of the mechanism for removing the physical barrier(s), once the physical barrier(s) is removed, the at least one first composition and the at least one second composition are mixed together in the dental form to form a third composition.
  • the mixing may occur simply after removal of the physical barrier(s) or, in at least one embodiment, by the user physically agitating the dental form for approximately 30 seconds. Once thoroughly mixed, the third composition cures over a period of time adjacent to the user's teeth, for example, from about 10 seconds to about 10 minutes. The mouthguard is formed upon completion of the curing step.
  • a dental form 12 comprises multiple first compositions 22 and multiple second compositions 26 disposed in a plurality of individual compartments 30 within the mold channel 14. Each of the compartments is separated by a rupturable membrane 24.
  • opposite edge portions of the rupturable membranes 24 are secured to the forward wall 18 and rear wall 20 of the dental form 12. A lower edge portion of each rupturable membrane 24 is secured with the base wall 16.
  • each rupturable membrane 24 is secured to a flexible membrane 28, which is adhered to portions of the dental form 12, along peripheral edge portions of the flexible membrane 28, effectively enveloping the individual compartments 30 that are that are filled with the first compositions 22 and second compositions 26.
  • the individual compartments 30 contain an alternating pattern of first and second compositions. However, any arrangement of the first and second compositions may be envisioned in this application.
  • a self-contained dental form 32 comprises at least one first composition 22 and at least one second composition 26 separated by a rupturable membrane 24.
  • the dental form 32 would be contained within a flexible membrane 28 and the compositions would be isolated from each other by a rupturable membrane 24.
  • the dental form 32 could be placed into the mold channel 14 of an exterior dental shell 12. In use, the user bites down on the insert 32, rupturing the internal rupturable membrane 24. The compositions are then allowed to mix together and at least partially cure. The finished mouthguard 10' would then release from the external dental shell 12 and function as a freestanding mouthguard 10' with minimal extra plastic bulk, similar to high end custom-fitted mouthguards.
  • the user may engage the at least one first and second compositions by various methods, such as biting, bending/twisting the dental form prior to inserting into the user's mouth, pinching a particular point on the dental form prior to inserting into the user's mouth, and removing a mechanical clip.
  • the user may further shake or manipulate the dental form to engage mixing of the resin components.
  • the user would then place the dental form into the user's mouth and bite down against the dental form for a
  • the mouthguard formed be disposable after a limited number of uses. This could be provided to athletes at low cost, while offering the athlete the ability to use a fresh mouthguard after a limited number of uses.

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  • Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dental Preparations (AREA)

Abstract

La présente invention concerne une forme dentaire comportant au moins une première composition et au moins une deuxième composition, ladite au moins une première composition et ladite au moins une deuxième composition produisant une réaction lorsqu'elles sont mélangées pour former une troisième composition. L'invention concerne également des prothèses protectrices et des trousses comprenant des formes dentaires.
PCT/US2014/072220 2014-01-10 2014-12-23 Prothese protectrice WO2015119720A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP14882099.6A EP3091956A4 (fr) 2014-01-10 2014-12-23 Prothese protectrice
CA2936386A CA2936386A1 (fr) 2014-01-10 2014-12-23 Prothese protectrice

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461926004P 2014-01-10 2014-01-10
US61/926,004 2014-01-10

Publications (1)

Publication Number Publication Date
WO2015119720A1 true WO2015119720A1 (fr) 2015-08-13

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Application Number Title Priority Date Filing Date
PCT/US2014/072220 WO2015119720A1 (fr) 2014-01-10 2014-12-23 Prothese protectrice

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EP (1) EP3091956A4 (fr)
CA (1) CA2936386A1 (fr)
WO (1) WO2015119720A1 (fr)

Citations (5)

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CA2936386A1 (fr) 2015-08-13
EP3091956A1 (fr) 2016-11-16

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