WO2015057836A3 - Hormone parathyroïdienne anabolique osseuse et analogues de protéine apparentée à l'hormone parathyroïdienne - Google Patents
Hormone parathyroïdienne anabolique osseuse et analogues de protéine apparentée à l'hormone parathyroïdienne Download PDFInfo
- Publication number
- WO2015057836A3 WO2015057836A3 PCT/US2014/060689 US2014060689W WO2015057836A3 WO 2015057836 A3 WO2015057836 A3 WO 2015057836A3 US 2014060689 W US2014060689 W US 2014060689W WO 2015057836 A3 WO2015057836 A3 WO 2015057836A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- parathyroid hormone
- analogs
- protein analogs
- bone anabolic
- methods
- Prior art date
Links
- 102000003982 Parathyroid hormone Human genes 0.000 title abstract 2
- 108090000445 Parathyroid hormone Proteins 0.000 title abstract 2
- 102100036899 Parathyroid hormone-related protein Human genes 0.000 title abstract 2
- 101710123753 Parathyroid hormone-related protein Proteins 0.000 title abstract 2
- 239000000199 parathyroid hormone Substances 0.000 title abstract 2
- 229960001319 parathyroid hormone Drugs 0.000 title abstract 2
- 230000001195 anabolic effect Effects 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 206010065687 Bone loss Diseases 0.000 abstract 2
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 208000020084 Bone disease Diseases 0.000 abstract 1
- 231100000360 alopecia Toxicity 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Abstract
La présente invention concerne une nouvelle hormone parathyroïdienne ainsi que des analogues de protéine apparentée à l'hormone parathyroïdienne. L'invention concerne également des méthodes d'utilisation d'un ou de plusieurs desdits analogues en vue de traiter un sujet souffrant d'une maladie osseuse associée à une perte osseuse. L'invention concerne en outre d'autres méthodes de traitement d'états pathologiques à l'aide d'un ou de plusieurs desdits analogues, notamment des méthodes de traitement de l'alopécie, de l'arthrite rhumatoïde, et de lésions/d'infections dérivant en une perte osseuse. L'invention concerne encore en outre de nouvelles formulations comprenant un ou plusieurs analogues.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361891151P | 2013-10-15 | 2013-10-15 | |
US61/891,151 | 2013-10-15 | ||
US201462022853P | 2014-07-10 | 2014-07-10 | |
US62/022,853 | 2014-07-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015057836A2 WO2015057836A2 (fr) | 2015-04-23 |
WO2015057836A3 true WO2015057836A3 (fr) | 2015-06-18 |
Family
ID=52828851
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2014/060689 WO2015057836A2 (fr) | 2013-10-15 | 2014-10-15 | Hormone parathyroïdienne anabolique osseuse et analogues de protéine apparentée à l'hormone parathyroïdienne |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2015057836A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6946182B2 (ja) | 2014-10-22 | 2021-10-06 | エクステンド バイオサイエンシズ インコーポレーテッドExtend Biosciences, Inc | 治療用ビタミンdコンジュゲート |
US9616109B2 (en) | 2014-10-22 | 2017-04-11 | Extend Biosciences, Inc. | Insulin vitamin D conjugates |
US11634468B2 (en) | 2019-01-29 | 2023-04-25 | Shire-Nps Pharmaceuticals, Inc. | Parathyroid hormone variants |
EP3712898A1 (fr) * | 2019-03-21 | 2020-09-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédé permettant de prédire si un receveur de greffe de rein présente un risque de subir un rejet d'allogreffe |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996007416A1 (fr) * | 1994-09-09 | 1996-03-14 | The Procter & Gamble Company | Oestrogenes et hormone parathyroidienne utiles pour traiter l'osteoporose |
US20040214996A1 (en) * | 2000-04-27 | 2004-10-28 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
US20070299009A1 (en) * | 1995-07-13 | 2007-12-27 | Dong Zheng X | Analogs of parathyroid hormone |
WO2010022176A1 (fr) * | 2008-08-19 | 2010-02-25 | Ferring International Center S.A. | Méthodes pour traiter des maladies du squelette |
-
2014
- 2014-10-15 WO PCT/US2014/060689 patent/WO2015057836A2/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996007416A1 (fr) * | 1994-09-09 | 1996-03-14 | The Procter & Gamble Company | Oestrogenes et hormone parathyroidienne utiles pour traiter l'osteoporose |
US20070299009A1 (en) * | 1995-07-13 | 2007-12-27 | Dong Zheng X | Analogs of parathyroid hormone |
US20040214996A1 (en) * | 2000-04-27 | 2004-10-28 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
WO2010022176A1 (fr) * | 2008-08-19 | 2010-02-25 | Ferring International Center S.A. | Méthodes pour traiter des maladies du squelette |
Also Published As
Publication number | Publication date |
---|---|
WO2015057836A2 (fr) | 2015-04-23 |
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