WO2015046654A1 - Système pour faire circuler un milieu de transfert d'ultrasons dans un dispositif de traitement par ultrasons concentrés à haute densité, et son procédé pour le faire circuler - Google Patents

Système pour faire circuler un milieu de transfert d'ultrasons dans un dispositif de traitement par ultrasons concentrés à haute densité, et son procédé pour le faire circuler Download PDF

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Publication number
WO2015046654A1
WO2015046654A1 PCT/KR2013/008749 KR2013008749W WO2015046654A1 WO 2015046654 A1 WO2015046654 A1 WO 2015046654A1 KR 2013008749 W KR2013008749 W KR 2013008749W WO 2015046654 A1 WO2015046654 A1 WO 2015046654A1
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WO
WIPO (PCT)
Prior art keywords
circulation
delivery medium
ultrasonic
passage
ultrasonic delivery
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PCT/KR2013/008749
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English (en)
Korean (ko)
Inventor
손건호
강국진
김대승
김명덕
Original Assignee
알피니언메디칼시스템 주식회사
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Publication of WO2015046654A1 publication Critical patent/WO2015046654A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid

Definitions

  • the present invention relates to a high-intensity focused ultrasound therapy device used to treat high heat generated by focus when high-intensity ultrasound energy is collected in one place, and more particularly, an ultrasonic delivery medium circulation system and circulation provided in a high-intensity focused ultrasound therapy device. It is about a method.
  • High-Intensity Focused Ultrasound is a procedure that burns and removes lesion tissue in the body by using high heat of 65-100 degrees centigrade at the focus when high-intensity ultrasound energy is collected in one place.
  • HIFU High-Intensity Focused Ultrasound
  • Ultrasound itself is harmless to the human body and heat is generated only at the focal point where the ultrasound is concentrated, so the lesions in the body can be treated non-invasive.
  • High-intensity focused ultrasound therapy is available for pancreatic cancer, uterine fibroids, liver cancer, etc., and active research is being conducted on prostate cancer, endometrial cancer, kidney cancer, breast cancer, soft tissue tumors, and bone tumors.
  • the head of the high intensity focused ultrasound therapy device has a high intensity focused ultrasound transducer at its end.
  • the high intensity focused ultrasound transducer is configured to emit high intensity focused ultrasound.
  • the ultrasonic radiating surface of the high intensity focused ultrasound transducer is covered by a membrane.
  • the ultrasonic wave transmission medium is accommodated in the receiving space formed between the ultrasonic radiating surface and the membrane.
  • Degassed water may be used as the ultrasonic delivery medium. This is because if undegassed water is used, bubbles are generated in the water when radiating high intensity focused ultrasound.
  • the head of the high-intensity focused ultrasound therapy device is positioned above the patient to emit high-intensity focused ultrasound through the ultrasonic radiating surface of the high-intensity focused ultrasound transducer while keeping the membrane in close contact with the patient's skin.
  • the high intensity focused ultrasound is then delivered to the lesion site of the patient via water in the receiving space.
  • the temperature of the water in the receiving space is very important in terms of stability.
  • the high-intensity focused ultrasound therapy when the high energy of the ultrasound is irradiated, energy is accumulated on the patient's skin, and burns may occur due to heat transmitted from the treatment area of the patient.
  • the water and the membrane in the receiving space may be raised to a temperature higher than the temperature of the patient's skin by high-intensity focused ultrasound. Since the membrane is in constant contact with the patient's skin during the high intensity focused ultrasound treatment, the patient's skin may be burned by hot water.
  • the high intensity focused ultrasound therapy may include a water circulation system for cooling the water in the receiving space.
  • the conventional water circulation system is configured to discharge the heated water in the receiving space by the discharge pump to the cooling tank, and to supply the cooled water in the cooling tank to the receiving space by the supply pump.
  • the amount of water circulation is small, it may take a long time for the water circulation.
  • the cooling tank since the cooling tank has an open structure through which external air passes, the amount of water in the accommodation space may vary due to the pressure difference between the cooling tank and the accommodation space.
  • An object of the present invention is to maintain a constant amount of the ultrasonic delivery medium in the receiving space during the circulation of the ultrasonic delivery medium to the receiving space of the high-intensity focused ultrasound therapy ultrasound of the high-intensity focused ultrasound therapy device that can quickly circulate the ultrasonic delivery medium
  • the present invention provides a circulation medium circulation system and a circulation method.
  • Ultrasonic delivery medium circulation system of the high-intensity focused ultrasound therapy device for achieving the above object is an ultrasonic delivery medium circulation system of the high-intensity focused ultrasound therapy device having a receiving space in which the ultrasonic delivery medium is accommodated, the circulation portion, And a cooling tank, a supply part, a discharge part, a first valve, and a second valve.
  • the circulation portion includes a first circulation passage connected to the inlet port of the accommodation space, a second circulation passage connected to the outlet port of the accommodation space, and a third circulation passage connected to the first circulation passage and the second circulation passage. Cooling and degassing while circulating the ultrasonic delivery medium in a predetermined amount.
  • the cooling tank stores and cools the ultrasonic transfer medium.
  • the supply unit supplies the ultrasonic transfer medium in the cooling tank to the first circulation passage through a supply passage connected to the first circulation passage and the third circulation passage.
  • the discharge unit discharges the ultrasonic transfer medium in the accommodation space to the cooling tank through the discharge passage connected to the second circulation passage and the third circulation passage.
  • the first valve selectively opens and closes the first and third circulation passages and the supply passage.
  • the second valve selectively opens and closes the second and third circulation passages and the discharge passage.
  • the ultrasonic delivery medium in the cooling tank is supplied by using at least one of the supply pump and the discharge pump while the connecting port of the first and second valves is blocked. Fill the receiving space and the first and second circulation flow paths through the flow path and the discharge flow path. Then, the ultrasonic transfer medium in the cooling tank is transferred to the third circulation passage by using at least one of the circulation pump, the supply pump, and the discharge pump, with the connector on the first and second circulation passages of the first and second valves blocked. Fill it. Then, the ultrasonic transfer medium filled in the accommodation space and the first, second, and third circulation passages by using the circulation pump is blocked with the connector on the supply flow path side of the first valve and the connection on the discharge flow path side of the second valve. Circulate
  • the discharge amount of the ultrasonic delivery medium discharged from the accommodation space of the high intensity focused ultrasound therapy device and the supply amount of the ultrasonic delivery medium supplied to the accommodation space may be the same. Therefore, the amount of the ultrasonic delivery medium in the accommodation space can be kept constant. In addition, since the amount of circulation of the ultrasonic delivery medium can be increased while the ultrasonic delivery medium in the receiving space is under pressure, the ultrasonic delivery medium in the receiving space can be cooled rapidly.
  • the ultrasonic delivery medium can be easily circulated with respect to the space.
  • FIG. 1 is a block diagram of the ultrasonic delivery medium circulation system of the high-intensity focused ultrasound therapy device according to an embodiment of the present invention.
  • FIG. 2 to 4 are diagrams for explaining an example of the ultrasonic delivery medium circulation method by the ultrasonic delivery medium circulation system shown in FIG.
  • FIG. 5 is a cross-sectional view illustrating an example of a cooling tank in FIG. 1.
  • FIG. 6 is a configuration diagram illustrating an example of a cooling device in FIG. 1.
  • FIG. 7 is a perspective view of the cooling apparatus of FIG. 6.
  • FIG. 8 is a configuration diagram showing another example of the cooling device in FIG. 1.
  • FIG. 9 is a block diagram of the ultrasonic delivery medium circulation system of the high intensity focused ultrasound therapy device according to another embodiment of the present invention.
  • FIG. 1 is a block diagram of the ultrasonic delivery medium circulation system of the high-intensity focused ultrasound therapy device according to an embodiment of the present invention.
  • the ultrasonic delivery medium circulation system 100 shown in FIG. 1 is for circulating the ultrasonic delivery medium with respect to the accommodation space 13 in the high intensity focused ultrasound therapy apparatus having an accommodation space 13 in which the ultrasonic delivery medium is accommodated.
  • the high-intensity focused ultrasound therapy device may include a head 10 that may be positioned in accordance with the treatment area of the patient from the upper side of the patient.
  • the head 10 of the high intensity focused ultrasound therapy may have a structure in which the high intensity focused ultrasound transducer 11 is positioned at an end thereof.
  • the high intensity focused ultrasound transducer 11 may have an ultrasonic radiating surface 11a at its lower end.
  • the ultrasonic radiation surface 11a may have a concave upward or flat structure.
  • Ultrasonic radiating surface 11a may be covered by membrane 12.
  • An accommodating space 13 may be formed between the ultrasonic radiating surface 11a and the membrane 12 to accommodate the ultrasonic transfer medium.
  • the ultrasonic delivery medium may be made of degassed water and the like.
  • An inlet port for introducing the ultrasonic delivery medium may be formed at one side of the accommodation space 13, and an outlet port for discharging the ultrasonic transfer medium may be formed at the other side of the accommodation space 13.
  • the membrane 12 may be made of a material having an acoustic impedance similar to that of the ultrasonic transmission medium, less ultrasonic transmission loss, and excellent elasticity.
  • the membrane 12 may be deformed into a substantially hemispherical shape convex downward when the ultrasonic delivery medium is filled in the receiving space 13 in a predetermined amount.
  • the head 10 of the high intensity focused ultrasound therapy device is positioned above the patient to emit high intensity focused ultrasound through the ultrasonic radiating surface 11a of the high intensity focused ultrasound transducer 11 in a state in which the membrane 12 is in close contact with the patient's skin. do. Then, the high intensity focused ultrasound is delivered to the lesion site of the patient via the ultrasound delivery medium in the receiving space (13).
  • the ultrasonic delivery medium circulation system 100 includes a circulation unit 110, a cooling tank 120, a supply unit 130, an discharge unit 140, a first valve 150, and a second valve 160. It includes.
  • the circulation unit 110 includes a first circulation passage 111a connected to the inlet port of the accommodation space 13, a second circulation passage 111b connected to the outlet port of the accommodation space 13, and a first circulation passage 111a. ) And a third circulation passage 111c positioned between the second circulation passage 111b and connected to the first circulation passage 111a and the second circulation passage 111b.
  • the circulation unit 110 performs cooling and degassing while circulating the ultrasonic delivery medium in a predetermined amount through the first, second, and third circulation passages 111a, 111b, and 111c with respect to the accommodation space 13.
  • the circulation unit 110 includes first, second and third circulation pipes 112a, 112b and 112c, a circulation pump 113, a cooling device 114, and a degasser 115. can do.
  • the first, second, and third circulation pipes 112a, 112b, and 112c form first, second, and third circulation passages 111a, 111b, and 111c, respectively.
  • the first, second, and third circulation pipes 112a, 112b, and 112c may be made of a material having high volume modulus, for example, plastic, metal, or hard rubber. Accordingly, it is possible to prevent the amount of the ultrasonic delivery medium accommodated in the accommodation space 13 during circulation of the ultrasonic delivery medium by the circulation unit 110.
  • the circulation pump 113 is installed in the third circulation pipe 112c to circulate the ultrasonic delivery medium with respect to the accommodation space 13.
  • the circulation pump 113 may be installed to connect the inlet and outlet to the third circulation pipe 112c.
  • the circulation pump 113 may suck the ultrasonic transfer medium in the accommodation space 13 through the third circulation pipe 112c and send it into the accommodation space 13.
  • the circulation pump 113 may be configured as an electric pump driven by a motor, and may be controlled by a controller for controlling the entire system 100.
  • the cooling device 114 is installed in the third circulation pipe 112c to cool the ultrasonic transmission medium flowing in the third circulation pipe 112c.
  • the ultrasonic delivery medium cooled by the cooling device 114 during the high intensity focused ultrasound treatment may be supplied into the accommodation space 13 by the circulation pump 113 and mixed with the heated ultrasonic delivery medium in the accommodation space 13. Therefore, the heated ultrasonic transmission medium in the accommodation space 13 can be cooled.
  • the circulation pump 113 is illustrated as being disposed before the cooling device 114, the cooling device 114 is a circulation pump It is also possible to arrange before the 113.
  • the degasser 115 is installed in the first circulation pipe 112a to degas the ultrasonic transmission medium flowing in the first circulation pipe 112a.
  • the ultrasound delivery medium is discharged from the accommodation space 13 into the first, second, and third circulation tubes 112a, 112b, and 112c.
  • the gaseous components in the ultrasonic delivery medium may be removed by the deaerator 115 and then supplied back into the receiving space 13.
  • Bubbles may be generated in the ultrasound delivery medium by the high intensity focused ultrasound during the high intensity focused ultrasound treatment. The bubbles generated can interfere with the ultrasound delivery and cause different ultrasound delivery paths.
  • bubbles may stick to the ultrasonic radiating surface 11a to cause failure of the high intensity focused ultrasound transducer 11. Therefore, if the ultrasonic delivery medium is degassed, the aforementioned problem can be prevented.
  • the degasser 115 may be configured as a vacuum degasser. Generally, since the evaporation amount of the dissolved gas in water is maximum at the boiling point, degassing can be performed at low temperature by lowering the boiling point using a vacuum.
  • the vacuum degasser can utilize the principles described above.
  • the vacuum deaerator may introduce the ultrasonic delivery medium into the vacuum vessel maintaining the vacuum state and discharge the dissolved gas component in the ultrasonic delivery medium out of the vacuum vessel by a vacuum pump or the like.
  • the cooling tank 120 stores and cools the ultrasonic transfer medium.
  • the supply unit 130 circulates the ultrasonic delivery medium in the cooling tank 120 along the first circulation passage 111a or the third circulation passage along the supply passage 131 connected to the first circulation passage 111a and the third circulation passage 111c.
  • Supply to flow path 111c may include a supply pipe 132 and a supply pump 133.
  • the supply pipe 132 forms a supply passage 131.
  • the supply pipe 132 is positioned between the first circulation pipe 112a and the third circulation pipe 112c and is connected to the first circulation pipe 112a and the third circulation pipe 112c.
  • Supply pump 133 may be installed so that the inlet and outlet is connected to the supply pipe (132).
  • the supply pump 133 may supply the ultrasonic transfer medium in the cooling tank 120 into the first circulation pipe 112a or the third circulation pipe 112c along the supply pipe 132.
  • the supply pump 133 may be configured as an electric pump and may be controlled by a controller.
  • the discharge unit 140 discharges the ultrasonic transfer medium in the accommodation space 13 to the cooling tank 120 along the discharge passage 141 connected to the second circulation passage 111b and the third circulation passage 111c.
  • the discharge unit 140 may include a discharge pipe 142 and the discharge pump 143.
  • the discharge pipe 142 forms the discharge passage 141.
  • the discharge pipe 142 is located between the second circulation pipe 112b and the third circulation pipe 112c and is connected to the second circulation pipe 112b and the third circulation pipe 112c.
  • Discharge pump 143 may be installed so that the inlet and outlet is connected to the discharge pipe (142).
  • the discharge pump 143 may discharge the ultrasonic transfer medium in the accommodation space 13 along the discharge pipe 142 to the cooling tank 120.
  • the discharge pump 143 may be configured as an electric pump and may be controlled by a controller.
  • the first valve 150 selectively opens and closes the first and third circulation passages 111a and 111c and the supply passage 131.
  • the first valve 150 may be installed at a portion where the first and third circulation pipes 112a and 112c and the supply pipe 132 are connected.
  • the first valve 150 may be a three way valve.
  • the three-way valve is one of the three holes to serve as the connector 151 of the third circulation passage side, the other one serves as the connector 152 of the first circulation passage side, the other one of the supply passage side It may function as a connector 153.
  • the second valve 160 selectively opens and closes the second and third circulation passages 111b and 111c and the discharge passage 141.
  • the second valve 160 may be installed at a portion where the second and third circulation pipes 112b and 112c and the discharge pipe 142 are connected.
  • the second valve 160 may also be a three-way valve.
  • the three-way valve is one of the three holes to serve as the connector 161 of the second circulation passage side, the other one serves as the connector 162 of the third circulation passage side, the other one of the discharge passage side It may function as the connector 163.
  • the first and second valves 150 and 160 may be controlled by a controller.
  • an example of the ultrasonic delivery medium circulation method by the ultrasonic delivery medium circulation system 100 described above is as follows.
  • the arrow indicates the flow of the ultrasonic delivery medium.
  • the supply pump 133 and the discharge pump 143 in a state in which the connectors 151 and 162 of the third circulation passage of the first and second valves 150 and 160 are blocked.
  • Ultrasonic delivery medium in the cooling tank 120 is filled in the receiving space 13 and the first and second circulation passages 111a and 111b through the supply passage 131 and the discharge passage 141 by using at least one of the at least one.
  • ultrasonic waves are transmitted to the accommodation space 13 and the first and second circulation passages 111a and 111b through the supply passage 131 in a state in which the connector 163 on the discharge passage side of the second valve 160 is blocked.
  • the connector 151 of the third circulation passage side is blocked by the first valve 150.
  • the second valve 160 blocks the connector 162 on the third circulation passage side and the connector 163 on the discharge passage side.
  • the ultrasonic delivery medium in the cooling tank 120 is sucked into the supply passage 131 by the supply pump 133, and then the connector 153 on the open supply passage side and the open first circulation passage side. It is sent out to the first circulation passage (111a) through the connector 152. Then, the ultrasonic delivery medium sent to the first circulation passage 111a may be degassed through the deaerator 115 and then supplied to the accommodation space 13.
  • the connector 153 on the supply flow path is blocked by the first valve 150.
  • the connector 163 on the discharge passage side is opened by the second valve 160.
  • the connector 151, 162 of the third circulation passage side is maintained in a state blocked by the first and second valves 150 and 160.
  • the ultrasonic delivery medium in the receiving space 13 is sucked by the discharge pump 143, and then, through the connector 161 on the open second circulation flow path and the connector 163 on the open discharge flow path. It is sent to the discharge passage (141). Then, the ultrasonic transmission medium sent to the discharge passage 141 may be stored in the cooling tank 120.
  • This process may be performed several times until the ultrasonic delivery medium is filled without bubbles in the accommodation space 13 and the first and second circulation passages 111a and 111b.
  • the ultrasonic delivery medium may also be filled in the deaerator 115 without bubbles.
  • the ultrasonic circulation medium is circulated by the circulation pump 113 from the supply passage 131 through the connector 153 of the open supply passage side and the connector 151 of the open third circulation passage side. After suctioning into the), it is sent to the discharge passage 141 through the connector 162 of the open third circulation passage side and the connector 163 of the open discharge passage side. This process is performed until the ultrasonic delivery medium is filled without bubbles in the third circulation channel 111c. In this case, the ultrasonic delivery medium may also be filled in the cooling device 114 without bubbles.
  • the ultrasonic delivery medium may be filled without bubbles in the receiving space 13 and the first, second, and third circulation passages 111a, 111b, and 111c.
  • the ultrasonic delivery medium may be filled without bubbles in the supply passage 131 and the discharge passage 141. 2 and 3 may correspond to the step of initializing the ultrasound delivery medium circulation system 100 before the high intensity focused ultrasound treatment. After performing the steps shown in FIG. 3, it is also possible to initialize the ultrasonic delivery medium circulation system 100 by performing the steps shown in FIG. 2.
  • the high intensity focused ultrasound treatment by the head 10 of the high intensity focused ultrasound therapy may be performed as follows.
  • the lesion site of the patient is pre-scanned while the membrane 12 of the head 10 is in contact with the patient's skin.
  • the ultrasonic wave is received in the accommodation space 13 by the supply unit 130 and the discharge unit 140.
  • the amount of medium can be adjusted. That is, by adjusting the amount of the ultrasonic delivery medium accommodated in the receiving space 13, the height of the ultrasonic radiation surface (11a) can be adjusted in the state that the membrane 12 is in contact with the skin of the patient.
  • the circulation pump 113 is used in a state in which the connector 153 on the supply flow path side of the first valve 150 and the connector 163 on the discharge flow path side of the second valve 160 are blocked.
  • the ultrasonic transfer medium in the receiving space 13 is sucked by the circulation pump 113 through the connector 161 on the second circulation passage side and the connector 162 on the third circulation passage side, and then opened.
  • the connector 151 of the third circulation passage side and the connector 152 of the first circulation passage side can be sent into the receiving space (13).
  • the ultrasonic transfer medium flowing through the third circulation passage 111c is cooled by the cooling device 114, and the ultrasonic transfer medium flowing through the first circulation passage 111a is degassed by the degasser 115.
  • the degasser 115 can be.
  • the heated ultrasonic delivery medium in the accommodation space 13 may be cooled.
  • the ultrasonic delivery medium since the ultrasonic delivery medium is filled in the receiving space 13 and the first, second, and third circulation passages 111a, 111b, and 111c without bubbles, the ultrasonic delivery medium discharged from the receiving space 13
  • the amount of ultrasonic delivery medium supplied to the accommodation space 13 may be the same. Therefore, since the ultrasonic delivery medium can be circulated in a predetermined amount along the first, second, and third circulation passages 111a, 111b, and 111c, the amount of the ultrasonic delivery medium in the accommodation space 13 can be kept constant. .
  • the circulation amount of the ultrasonic delivery medium can be increased, the ultrasonic delivery medium in the accommodation space 13 can be cooled rapidly.
  • the same pressure acts on the accommodation space 13 and the first, second, and third circulation passages 111a, 111b, and 111c, the ultrasonic waves in the accommodation space 13 through the membrane 12 during the high intensity focused ultrasound treatment. Even if the delivery medium is under pressure, the ultrasonic delivery medium can be easily circulated to the accommodation space 13.
  • the amount of circulation of the ultrasonic delivery medium may be set so that the flow of the ultrasonic delivery medium in the receiving space 13 is not severe.
  • a break may be provided after the high-intensity focused ultrasound is irradiated once.
  • the ultrasonic delivery medium may be circulated as necessary in the step shown in FIG. 4.
  • high intensity focused ultrasound irradiation may not perform the step shown in Figure 4.
  • FIG. 5 is a cross-sectional view showing an example of a cooling tank.
  • the cooling tank 120 shown in FIG. 5 has a storage space for storing the ultrasonic delivery medium therein.
  • the cooling tank 120 may have a supply pipe 132 mounted on one side thereof and may be connected to a storage space and a supply flow path, and a discharge pipe 142 may be mounted on the other side thereof to connect the storage space and a discharge flow path.
  • the upper portion of the cooling tank 120 has a structure in which air can enter and exit the storage space. For example, at least one hole 121 may be formed at an upper portion of the cooling tank 120.
  • the process of supplying the ultrasonic transfer medium from the cooling tank 120 to the receiving space 13 by the supply unit 130, and discharged from the receiving space 13 to the cooling tank 120 by the discharge unit 140 since the air can enter and exit the storage space of the cooling tank 120, the first, second, third circulation pipe (112a) (112b) (112c), supply pipe 132, discharge pipe 142, cooling tank Excessively high pressure in 120 can be prevented.
  • the cooling tank 120 may have cooling means such as a chiller 122 for cooling the ultrasonic delivery medium in the storage space.
  • the chiller 122 may be configured to cool the ultrasonic transfer medium by exchanging a refrigerant with the ultrasonic transfer medium.
  • FIG. 6 is a configuration diagram showing an example of a cooling device.
  • 7 is a perspective view of the cooling apparatus of FIG. 6.
  • the cooling device 114 shown in FIGS. 6 and 7 may include a storage container 114a and a cooler 114b.
  • the storage container 114a stores the ultrasonic delivery medium therein.
  • the storage container 114a has a structure in which portions other than the inlet and outlet portions connected to the third circulation pipe 112c are closed. When the ultrasonic delivery medium is filled without bubbles in the third circulation pipe 112c, the ultrasonic delivery medium may be filled without bubbles even in the storage container 114a. Therefore, since the pressure difference between the storage container 114a and the accommodation space 13 does not occur, the amount of the ultrasonic transfer medium in the accommodation space 13 may not be changed.
  • the storage container 114a may be made of a material having high volume modulus, for example, plastic or metal material.
  • the cooler 114b cools the ultrasonic transfer medium in the reservoir 114a.
  • the cooler 114b may include a heat exchanger through which a refrigerant flows.
  • the heat exchanger may be located in the storage container 114a and in contact with the ultrasonic transfer medium in the storage container 114a. As the refrigerant of the heat exchanger deprives heat of the ultrasonic transfer medium in the storage container 114a, the ultrasonic transfer medium may be cooled.
  • the cooler may include a thermoelement.
  • a thermoelectric element is an element capable of generating endothermic or exothermic heat by using a Peltier effect, a phenomenon in which heat is absorbed or generated by an electric current.
  • the thermoelectric element may be installed in the storage container 114a and controlled to absorb heat from the storage container 114a, thereby cooling the ultrasonic transfer medium in the storage container 114a.
  • the ultrasonic delivery medium may be cooled in various ways, such as by storing ice in the storage container 114a, the ultrasonic delivery medium is not limited thereto.
  • FIG. 8 is a configuration diagram showing another example of the cooling device.
  • the cooling device 214 shown in FIG. 8 may include a heat exchange tube 214a and a cooling heat exchanger 214b.
  • the heat exchange tube 214a has an ultrasonic transfer medium therein and is connected to the inlet and outlet of the third circulation tube 112c.
  • the heat exchange tube 214a may be formed in a zigzag bent several times.
  • the cooling heat exchanger 214b cools the ultrasonic transfer medium in the heat exchanger tube 214a through heat exchange with the heat exchanger tube 214a.
  • a refrigerant may flow therein.
  • the cooling heat exchanger 214b may be configured such that the refrigerant is in contact with the heat exchanger tube 214a by placing the heat exchanger tube 214a therein. As the refrigerant in the cooling heat exchanger 214b deprives heat of the ultrasonic transfer medium in the heat exchange tube 214a, the ultrasonic transfer medium may be cooled.
  • FIG. 9 is a block diagram of the ultrasonic delivery medium circulation system of the high intensity focused ultrasound therapy device according to another embodiment of the present invention.
  • the circulation pump 113 is installed in the second circulation pipe 112b.
  • the cooling device 114 is installed in the third circulation pipe 112c.
  • the degasser 115 is installed in the first circulation pipe 112a.
  • the discharge part 240 includes a discharge pipe 242 having one end connected between the second circulation pipe 112b and the third circulation pipe 112c and having the other end connected to the cooling tank 120. Therefore, the ultrasonic delivery medium circulation system 200 according to the present embodiment may omit the discharge pump 143 of the ultrasonic delivery medium circulation system 100 according to the above-described embodiment, thereby simplifying the configuration and reducing the manufacturing cost. There may be a savings.

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Abstract

L'invention concerne un système pour faire circuler un milieu de transfert d'ultrasons, qui comprend : une unité de circulation, un réservoir de refroidissement, une unité d'alimentation, une unité d'évacuation, une première valve et une seconde valve. L'unité de circulation comprend un premier canal de circulation qui est relié à un orifice d'entrée d'un espace de réception, un deuxième canal de circulation qui est relié à un orifice de sortie de l'espace de réception, et un troisième canal de circulation qui est relié au premier canal de circulation et au deuxième canal de circulation, de telle sorte que, lorsqu'une quantité prédéterminée de milieu de transfert d'ultrasons circule dans l'espace de réception, l'unité de circulation refroidit et dégaze le milieu de transfert d'ultrasons. Le réservoir de refroidissement stocke et refroidit le milieu de transfert d'ultrasons. L'unité d'alimentation achemine le milieu de transfert d'ultrasons à l'intérieur du réservoir de refroidissement dans le premier canal de circulation par l'intermédiaire d'un canal d'alimentation, qui est relié au premier canal de circulation et au troisième canal de circulation. L'unité d'évacuation évacue le milieu de transfert d'ultrasons à l'intérieur de l'espace de réception dans le réservoir de refroidissement par l'intermédiaire d'un canal d'évacuation, qui est relié au deuxième canal de circulation et au troisième canal de circulation. La première valve ouvre/ferme sélectivement les premier et troisième canaux de circulation et le canal d'alimentation. La seconde valve ouvre/ferme sélectivement les deuxième et troisième canaux de circulation et le canal d'évacuation.
PCT/KR2013/008749 2013-09-30 2013-09-30 Système pour faire circuler un milieu de transfert d'ultrasons dans un dispositif de traitement par ultrasons concentrés à haute densité, et son procédé pour le faire circuler WO2015046654A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130116414A KR101533401B1 (ko) 2013-09-30 2013-09-30 고강도 집속 초음파 치료기의 초음파 전달매질 순환시스템 및 순환방법
KR10-2013-0116414 2013-09-30

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WO2015046654A1 true WO2015046654A1 (fr) 2015-04-02

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CN107082517A (zh) * 2017-06-05 2017-08-22 中惠医疗科技（上海）有限公司 用于相控阵列聚焦超声子宫肌瘤治疗系统水处理系统

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KR102598515B1 (ko) * 2023-04-17 2023-11-07 (주)아이엠지티 초음파 치료 헤드의 초음파 전달 매질 순환 시스템 및 그 방법

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JPH06237993A (ja) * 1993-02-17 1994-08-30 Terumo Corp 流体供給装置
JP2004097402A (ja) * 2002-09-06 2004-04-02 Toshiba Corp 超音波照射装置
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KR20130063614A (ko) * 2011-12-07 2013-06-17 원텍 주식회사 비만 치료용 핸드피스 및 비만 치료장치

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EP0404121A1 (fr) * 1989-06-21 1990-12-27 Kabushiki Kaisha Toshiba Appareil de thérapie par ondes acoustiques
JPH06237993A (ja) * 1993-02-17 1994-08-30 Terumo Corp 流体供給装置
JP2004097402A (ja) * 2002-09-06 2004-04-02 Toshiba Corp 超音波照射装置
US20100016764A1 (en) * 2006-12-18 2010-01-21 Francois Lacoste Therapeutic Treatment Head, Therapeutic Treatment Appliance, Method of Sequencing Activation Stages for the Head, and Method of Indirectly Determining the Temperature of the Skin
KR20130063614A (ko) * 2011-12-07 2013-06-17 원텍 주식회사 비만 치료용 핸드피스 및 비만 치료장치

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107082517A (zh) * 2017-06-05 2017-08-22 中惠医疗科技（上海）有限公司 用于相控阵列聚焦超声子宫肌瘤治疗系统水处理系统

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