WO2015006895A1

WO2015006895A1 - Formula of hair regrowth chinese medicine preparation and preparation method thereof

Info

Publication number: WO2015006895A1
Application number: PCT/CN2013/079356
Authority: WO
Inventors: 田艺儿
Original assignee: Tian Yi Er
Priority date: 2013-07-15
Filing date: 2013-07-15
Publication date: 2015-01-22

Abstract

Disclosed in the present invention is the formula of a hair regrowth Chinese medicine preparation and a preparation method thereof. The preparation of the present invention is a composition of a paste preparation prepared by the processes of mixing, pulverizing, decocting, stirring, etc. of tea seed oil, fresh ginger juice, black pig bile, wormwood, smilax glabra, fructus kochiae, rhododendron molle, rhizoma drynariae, orange pips, centipedes, torreya grandis seeds, mulberry leaf, scouring-rush, snake slough, eucommia ulmoides, morinda officinalis, spatholobus suberectus and curcuma aromatica. The present invention is suitable for hair and scalps of various features, and no allergic reactions and toxic side effects will occur after washing hair with the preparation, thus enabling a drug to rapidly penetrate and be absorbed by skin to achieve the purpose of hair regrowth. Moreover, the present invention has a quick and good hair regrowth and hair growth effect, is low in cost, and simple and easy in preparation process.

Description

Formula and preparation method of raw hair traditional Chinese medicine preparation

The invention relates to a traditional Chinese medicine preparation for germinating action, in particular to a traditional Chinese medicine preparation and a preparation method relating to the hair growth effect. Background technique

In the high-efficiency and fast-paced working life of modern cities, people's de-discovery is increasing and becoming more and more serious. Especially young people are often troubled by black hair that has fallen off very early. Currently, pharmaceutical preparations for treating hair loss are on the market. Quite a lot, but for western medicine, first, the price is relatively expensive, and the treatment for several courses of treatment adds a lot of economic burden to the patient. Second, the long-term medication is easy to bring certain side effects to the body function; Pure Chinese medicine on the body, slow in effect, unstable, stimulating effect on the hair follicles of the head. Although some hairs are temporarily present, if the medicine is stopped, the new hair will fall off easily, which is mainly due to the lesion of the hair follicle and the lack of hair growth environment. Nutrition-related, patients need to have a good effect, make hair growth lasting, and relatively inexpensive drugs to solve the above problems.

The object of the present invention is to provide a traditional Chinese medicine preparation for germinating effect on the basis of the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and in particular to provide such a preparation for promoting hair growth and a preparation method thereof. The preparation can be applied to the scalp of various characteristics. After washing the hair, there is no allergic reaction, no toxic and side effects, so that the drug can It quickly penetrates into the skin to achieve the purpose of hair growth, and the cost is low, and the preparation process is simple and easy. The technical solution of the present invention is as follows:

The preparation of the invention is made up of tea seed oil, ginger juice, black pig bile, capillaris, earthworm, koji, safflower, smashed, orange nucleus, medlar, medlar, mulberry leaf, Equisetum, viper a paste preparation prepared from Eucommia, Eucommia, Basil, Spatholobus, and turmeric,

The mass ratio of each component is:

Tea seed oil, ginger juice, black pig bile, Yin Chen, earthworm, Kochia scoparia

Wild sheep, broken bones, orange kernel

蜈蚣榧榧桑

Equisetum, snake, eucommia

Bashu, spatholobus, turmeric

In order to obtain a better effect, the preferred raw material quality ratio of the present invention is: Tea seed oil Ginger juice Black pig bile Yin Chen Earthworm Kochia scoparia

Wild sheep, broken bones, orange kernel

蜈蚣榧榧桑

Equisetum, snake, eucommia

Bashu, spatholobus, turmeric

Of course, in order to obtain further good effects, the present invention may also preferably optimize the quality of the raw materials with tea seed oil, ginger juice, black pig bile Earthworm 30g Kochia scoparia 20g Ramen 15g smashed 25g orange nucleus 20g 蜈蚣 3 scorpion 30g mulberry 40g sage 40g snake scorpion 30g eucommia 40g scorpion 40g spatholobus 40g turmeric 18g _t above raw hair Chinese medicine preparation The preparation method comprises the following steps:

Bandits, Kochia scoparia, ramie, smashed, orange nucleus, 蜈蚣 proportioned, smashed through a pulverizer and passed through a 80 mesh sieve, then dried at a high temperature of 50-70 ° C, then naturally dry Stand by to room temperature;

2) Put the tea seed oil in a wok and heat it to 90-120 degrees Celsius, then put the powder of capillaris, earthworm, Kochia scoparia, safflower, smashed, orange kernel, and simmer into the pan. Deep-fried with tea seed oil, take out the oil after 15 minutes;

3), put the above clear oil into a ceramic jar, then add black pig bile, stir for five minutes, and then let stand for at least one night to form a paste preparation;

4), the hazelnut, mulberry leaf, Equisetum, Viper, Eucommia, Basil, Spatholobus, turmeric, proportioned well, crushed by a pulverizer and passed through a 80 mesh sieve, then at 50-70 ° C Dry at high temperature, then naturally dry to room temperature for use;

5), at room temperature, the paste preparation in the above step 3) is added to the remaining hazelnut, mulberry leaf, Equisetum, Viper, Eucommia, Basil, Spatholobus, turmeric mixture, and then stirred evenly; The bell, finally installed in a porcelain jar, is ready.

The prepared cream preparation is used to wipe the scalp alone or to clean the hair. If it is mixed into a common shampoo, the effect will be better. The theoretical basis of the invention lies in: tea seed oil, also known as camellia oil, wild camellia oil, camellia seed oil, tea seed oil is a unique woody oil in China, its fatty acid composition and the world's best recognized vegetable oil olive oil Similarly, there is the name of "Oriental Olive Oil". Tea oil contains a variety of functional ingredients, with obvious effects of preventing cardiovascular cirrhosis, promoting metabolism, lowering blood pressure, lowering blood fat, and the special effects of anti-cancer and anti-cancer. Ginger juice is washed by the Zingiber officinale Rose. It is smashed and the juice is taken. Its taste is tender, slightly warm. In combination with other Chinese herbal medicines, wiping the scalp or washing the hair can stimulate skin congestion and improve local blood circulation to promote hair growth. Black pig bile, is a very good Chinese herbal medicine, Chinese medicine to treat a variety of diseases, the main components of juice are bile acids, bile pigments, mucin, lipids and inorganic substances. It tastes bitter, cold and salty; it can relieve phlegm and relieve cough and relieve asthma, and benefit the lungs, tonifying the spleen and moistening dryness. Yinchen, also known as Yinchenhao, Yinchen English name Capi llary Wormwood Herb, Chun was born because of Chen Gen, hence the name is Chen or Yinchen. It is also known as Artemisia sinensis. Taste bitter, spicy, slightly cold. Return to the spleen, stomach, liver, gallbladder. Yinchenqing heat and dampness; Indications: Astragalus, dysuria, wet sore itching, infectious jaundice hepatitis. Pharmacological research is beneficial to the gallbladder, protect liver function, antipyretic, anti-inflammatory, hypolipidemic, antihypertensive, and expand the crown. The bandit is a perennial evergreen climbing shrub of the family Liliaceae. It is mostly born on a hillside or under the forest. English name: Glabrous Greenbrier Rhizome, Sexual taste: sweet, flat. Return to the classics: liver; stomach; spleen. Function: Detoxification, anti-tumor, dehumidification, and joints. Indications: Treatment of syphilis, turbidity, muscle aches and pains, athlete's foot, hemorrhoids, carbuncle, phlegm, syphilis and mercury poisoning caused by limbs, muscle pain. Kochia scoparia, alias broomstick, Thousand-striped son, English name Fructus Kochiae, is the fruit of Kochia scoparia (L.) Schrad., which is cold, spicy and bitter. It can clear away heat and dampness, hurricane and itching. Lamb, also known as yellow azalea, yellow azalea, is a member of the genus Rhododendron of the family Ericaceae. It is one of the famous poisonous plants. It is a common Chinese herbal medicine and is often used as an anesthetic and analgesic in medicine. It can treat rheumatoid arthritis and bruises. Drynaria, minced meat, stone rock ginger, monkey ginger, hair ginger, Shen Jiang, climbing rock ginger, rock and ginger, English name Rhizoma Drynariae, bitter, warm. Return to the kidney, liver. It can strengthen the kidney and strengthen the bones. For kidney deficiency, low back pain, tinnitus and deafness, loose teeth, falling and fluttering, skeletal fractures; external treatment of alopecia areata, less hair, etc., compatible with other herbs, can effectively promote hair growth. Orange nucleus, also known as orange nucleus, orange kernel, orange rice, is the seed of the plant ripe fruit of Citrus tangerina Hort. et Tanaka or C. erythrosa Tanaka, which is prolific in Fujian, Zhejiang. In Guangdong, Guangxi, Jiangxi, Hunan, Guizhou, Yunnan, Sichuan and other places, collect the seeds after eating, wash, dry, and use. Containing yellow Cyperlactone, brain rice, protein and fatty oils. Taste bitter, Xin, Ping, liver, kidney, lung, bladder, can be toxic, anti-cancer, stagnation and swelling, with significant anti-tumor effect.蜈蚣, It is a common Chinese medicinal material for the giant scorpion scorpion or its relative animal. It has a hurricane, a stun, a poisoning, and a dispersing effect. It can be used to treat stroke, epileptic seizure, tetanus, whooping cough, sputum, white baldness, sputum, scald, etc., used in the present invention, and has the effect of promoting hair growth. Gardenia, a seed of the yew family. Alias, 榧, quilt, 玉山果, 赤果, 玉榧, 香榧, 野杉子, 甘甘; 涩; sex, into the lungs, stomach, large intestine, insecticide, elimination, moistening. Mulberry leaves are the dry leaves of the mulberry plant, also known as mulberry, mulberry, mulberry, and yellow mulberry. They are produced in most parts of the country and have the functions of lowering blood pressure, blood fat, anti-inflammatory, etc., and can evacuate wind and heat. Qingfei Runzao, calming liver and yang, clearing liver and eyesight, cooling blood to stop bleeding. It has been recorded in the ancient Chinese medical directory "The Record of Keeping Lives" that the mulberry leaves can be "retained in the face, black hair, filled with marrow, and dysentery". Equisetum, perennial erect herb, high 0.5 to 2 meters. Stems hollow and knotted, internodes 2 to 6 cm long, with longitudinal ribs on the surface, rough, degenerated leaves and stalks, sporangium stalks oblong, yellow, stalk apex, densely lanceolate. Like to be born in the river beach, the riverside and other wet places. Cut in summer and autumn, remove impurities, dry or dry. Equisetum is sweet; bitter; flat; non-toxic; slightly cold. Can clear the liver and eyesight, stop bleeding, diuretic Tonglin. Viper, English name PERIOSTRACUMSERPENTIS, alias snake skin, snake retreat, long worm skin, dragon coat, snake shell, for the snake family, the black-breasted snake Elaphetaeniura Copa, the golden snake Elaphecarinata CGuenther) or the black-snake snake Zaocysdhumnades (Cantor) Dry the epidermis. Collected at the end of spring or early summer or early winter, remove the sediment and dry. The snake smells salty, sweet, and flat. Going to the liver, you can hurricane, fix the shock, detoxification. Eucommia ulmoides, the dry bark of Eucommia ulmoides Oliver, is a valuable nourishing herb in China. It is listed as the top grade by the ancient Chinese medical book Shennong Bencao. It is said that it is "indications of waist and knee pain, supplementing the middle, benefiting the essence, strengthening the bones and muscles, except for the itch under the yin and urinating the rest. Long clothes, light and old." Eucommia ulmoides is a unique Chinese medicinal material with a long history of medicinal use. Clinically, it has a wide range of applications. Eucommia ulmoides has liver and kidney, strong bones and muscles, removes body waste, strengthens human body cell metabolism, prevents musculoskeletal aging, balances blood pressure, decomposes body cholesterol, lowers body fat, restores blood vessel elasticity, diuretic heat, broad-spectrum antibacterial, excites central nervous system , to improve the number of white blood cells, enhance the body's immunity and other significant effects. It is used in the present invention to nourish head nutrition and promote hair regeneration. Bashu, also known as chicken intestine, Ba Shutian, root for medicinal purposes, as a strong agent, has the effect of tonifying kidney and strengthening yang, strengthening bones and muscles, and rheumatism. It is slightly warm, sweet and spicy, can make kidney yang, strong bones, rheumatism. The spatholobus (scientific name: Mi llettia dielsiana) is a plant of the genus Leguminosae, which is bitter, sweet and warm. Going to the liver, kidney, attending to promote blood circulation, nourishing blood and regulating menstruation, the main hand and foot numbness, in the medicinal value, there is the effect of Qi, Fufeng, Huoxue. Yujin, Weixin, bitter, cold. Returning to the liver, heart, lungs, with the use of gasification, clear heart and phlegm, spleen and yellow, blood and pain, qi and qi, clear heart and blood, and other Chinese medicines in the invention, can promote metabolism, which is beneficial to Head hair follicle secretion. It is called "oily wind" and "sweet hair" in Chinese medicine, which belongs to the category of modern medical alopecia areata and male pattern hair loss (seborrheic alopecia). The cause of hair loss has not been fully understood in medicine. Most of them are related to genetic factors, fungal infections, autoimmunity, endocrine dysfunction, low stress ability, radiation, chronic poisoning, trace element deficiency, and mental stress. Chinese medicine believes that: it is blood. The cause of hair loss caused by traditional Chinese medicine is mostly due to weak heart and blood, lack of liver blood, resulting in blood deficiency and wind, wind and dryness can not nourish skin and hair; or liver qi stagnation, poor air, resulting in qi stagnation, hair Lost or raised; or liver and kidney yin deficiency, blood loss, dryness and loss; or overeating spicy, greasy, resulting in moisture accumulation, loss of support, hair roots are not solid; or because of excessive thinking, troubles, As a result, blood is hot and windy, and the wind is moving.

The combination of the above compositions can enhance the conditioning effect, and with the mineral oil and various kinds of vitamin E, vitamin B1, linoleic acid, protein, sesame, polypentose, calcium, pity, iron and the like in tea seed oil The combination of rich nutrients further regulates the body's functions, promotes hair growth, enhances the elasticity and luster of the hair, and makes the hair loose and easy to comb. Clinical trial 1:

1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the time from January 2013 to July 2013 is selected.

2), observation object: 40 cases were selected in the Chinese Medicine Hospital of Shenzhen, Guangdong Province: 20 males, 20 females; Age: 18-25 years old, 18 cases, 25-35 years old 22 cases; Occupation: 10 students, 10 workers, 5 farmers, 10 teachers, 5 other. Course of disease: From the onset to the time of treatment, 20 cases in 2 years, 10 cases in 2-4 years, and 10 cases in 4 years.

3), How to use: Wash the hair with the shampoo of the preparation of the invention, 3 times a day, 1 hour after each meal, 1 month for 1 course, 6 courses as efficacy observation.

4), observation effect:

The effect criteria are: significant, hair loss is not obvious, giving birth to small hair more than 10%; effective, giving birth to small hair more than 5%, hair loss is controlled; invalid, hair loss is basically no improvement and reduction.

Results Of the 40 cases, 20 were significant, 13 were effective, and 7 were ineffective. The total effective rate was 82.5%.

Clinical trial 2:

1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the period of 6 months from December 2012 to May 2013 is selected.

2) Observation object: 20 cases were selected in Shenzhen Hospital of Guangdong Province: 10 males and 10 females; age: 8 cases of 16-25 years old, 12 cases of 25-35 years old; occupation: 10 students, workers 2 For example, there are 2 farmers, 2 teachers, and 4 others. Course of disease: From the onset to the time of treatment, 10 cases in 2 years, 5 cases in 2-4 years, and 5 cases in 4 years.

3), How to use: Wash the hair of the preparation of the invention 3 times a day, 1 hour before each meal, 1 month for 1 course, 6 courses as efficacy observation.

4), observation effect:

The effect criteria are divided into: significant, hair loss is not obvious, giving birth to small hair more than 10%; effective, Hair loss of more than 5%, hair loss is controlled; invalid, hair loss is basically no improvement and relief.

Results Of the 20 cases, 14 were significant, 2 were effective, and 4 were ineffective. The total effective rate was

80%.

Combined with the above clinical data and the theoretical basis of the present invention, it can be seen that the preparation prepared by the invention can be applied to hair and scalp of various characteristics, and has no allergic reaction after washing the hair, has no toxic and side effects, and makes the drug It can quickly penetrate into the skin to achieve the purpose of hair growth, and it has quick effect, good hair growth and hair-raising effect, low cost and easy preparation process. Specific real

The present invention will be described in detail below with reference to the embodiments.

Example 1:

The mass ratio of each component is

Tea Seed Oil 1200g Ginger Juice 100g Black Pig Bile 40g

Yin Chen 20g Bandit 20g Kochia scoparia 20g

Raising sheep flower 10g bone crushing 20g orange kernel 15g

蜈蚣 3 scorpions 20g mulberry leaves 30g

Equisetum 30g Viper 20g Eucommia 30g Basil 30g spatholobus 30g turmeric 15g.

The preparation method of the above-mentioned raw Chinese medicine preparation comprises the following steps:

1), Yinchen, earthworm, Kochia scoparia, ramie, bone shredding, orange kernel, sputum proportioned, after crushing machine and passing 80 mesh sieve, then at 50-70 ° C high temperature Dry down, then naturally dry to room temperature for use;

5), at room temperature, the paste preparation in the above step 3) is added to the remaining hazelnut, mulberry leaf, Equisetum, Viper, Eucommia, Basil, Spatholobus, turmeric mixture, and then stirred evenly;

6), the above paste preparations are stirred once a day, morning and evening, 10 minutes each time, after three days, slightly fry for half an hour, and then allowed to stand at room temperature, then add ginger juice, and stir for 10 minutes, and finally in porcelain Serve after the can.

The prepared cream preparation is used to wipe the scalp alone or to clean the hair. If it is mixed into a common shampoo, the effect will be better.

Example 2: The preferred raw material quality of the present invention is (g):

Tea seed oil 1600g ginger juice 180g black pig bile 60g Yinchen 40g bandit 40g Kochia scoparia 30g ramie 20g smashed 30g orange kernel 25g 蜈蚣 3 scorpion 30g mulberry 40g sage 40g snake scorpion 30g eucommia 40g戟40g spatholobus 40g turmeric 20g. The preparation method is as in Example 1.

Example 3:

The mass of each component is (g):

Tea seed oil 1400g ginger juice 160g black pig bile 40g Yinchen 30g soil glutinous rice 30g Kochia scoparia 20g ramming flower 15g bone smashing 25g orange nucleus 15g 蜈蚣 3 scorpion 25g mulberry 35g sage 35g snake scorpion 25g eucommia 35g戟35g spatholobus 38g turmeric 16g.

Black pig bile 60g Kochia scoparia 30g orange kernel 20g 蜈蚣3 scorpions 30g mulberry leaves 40g squid 40g snake python 30g eucommia 40g

Basil 36g spatholobus 36g turmeric 17g.

Example 5

The mass of each component is (g):

Tea seed oil 1600g ginger juice 180g black pig bile 60g Yinchen 30g soil glutinous rice 30g Kochia scoparia 20g ramie 15g bone smashed 25g orange nucleus 20g 蜈蚣 3 scorpions 30g mulberry leaves 40g Equisetum 40g Viper 30g Eucommia 40g戟40g spatholobus 40g turmeric 18g.

The above embodiments are only a few of the various embodiments of the present invention. For example, if the formula is increased or decreased according to the ratio in the technical solution, the curative effect of the prepared hair preparation is not affected, and will also fall into the present. Within the scope of the rights of the invention

Claims

claims

1. The formula of a traditional Chinese medicine preparation for hair growth, which is characterized in that the preparation of the present invention is composed of tea seed oil, ginger juice, black pig bile, artemisia, smilax, kochia, rhizome, rhizome, and orange core , centipede, torreya, mulberry leaves, horsetail, snake slough, Eucommia ulmoides, Morinda citrifolia, Millet Spatholobus, and turmeric, a composition paste preparation,

The mass ratio of each component is:

Tea seed oil 1200-1600g Ginger juice 100-180g Black pig bile 40_60g Artemisia 20-40g Smilax _20-40g Kochia 20-30g Fragrance 10-20g Drynaria 20-30g Orange core 15-25g Centipede 3 torreya seeds 20-30g, mulberry leaves 30-40g, horsetail 30-40g, snake slough 20-30g, Eucommia ulmoides 30-40g, Morinda citrifolia 30-40g, Millet Spatholobus 30-40g, turmeric 15-20g.

2. The formula of a hair-growing traditional Chinese medicine preparation according to claim 1, further characterized in that the mass ratio of each component is:

Tea seed oil 1400-1600g, ginger juice 160-180g, black pig bile 40_60g, artemisia 30-40g, smilax 30-40g, kochia 20-30g, rhizome 15-20g, drynaria 25-30g, orange core 15-20g, centipede 3 Torreya 25-30g, mulberry leaves 35-40g, horsetail 35-40g, snake slough 25-30g, eucommia 35-40g, Morinda 35-40g, Millet Spatholobus 35-40g, turmeric 15_18g.

3. The formula of a hair-growing traditional Chinese medicine preparation according to claim 1 or 2, which is particularly Tea seed oil 1600g Ginger juice 180g Black pig bile 60g Artemisia 30g Smilax 30g Kochia 20g Sheepflower 15g Drynaria 25g Orange core 20g 3 centipedes 30g Mulberry leaves 40g Equisetum 40g Snake slough 30g Eucommia 40g Ba 40g of Halberd, 40g of Millet Spatholobus and 18g of Turmeric.

4. A method for preparing a hair-growing traditional Chinese medicine preparation, which is characterized in that it includes the following: Smilax cocos, kochia chinensis, rhizome of crocodile root, rhizome rhizome, tangerine core and centipede are prepared in proportion, crushed by a grinder and passed through 80 Mesh sieve, then dry at high temperature of 50-70°C, and then naturally air to room temperature for later use;

2). Heat the tea seed oil in an iron pot to 90-120 degrees Celsius, then add the powders of artemisia, smilax, kochia, rhizome, drynaria, orange core and centipede into the oil pan. Fry it with tea seed oil. After fifteen minutes, remove the clear oil and set aside;

3). Put the above-mentioned clear oil into a ceramic jar, then add black pig bile, stir for five minutes, and then let it stand for at least one night to form a paste preparation;

4). Mix torreya, mulberry leaves, horsetail, snake slough, Eucommia ulmoides, Morinda citrifolia, Millet Spatholobus, and turmeric in proportion, crush them in a crusher and pass through an 80-mesh sieve, and then grind them at 50-70°C. Dry at high temperature, then let it air to room temperature for later use;

5). At room temperature, add the paste preparation in the above step 3) to the remaining torreya, mulberry leaves, horsetail, snake slough, eucommia, morinda, millipedia, and turmeric mixture, and then stir evenly; 6) Stir the above paste preparation once a day in the morning and evening for 10 minutes each time. After three days, fry over low heat for half an hour and let it stand to room temperature. Then add ginger juice and stir for 10 minutes. Finally, put it on a porcelain plate. Serve after canning.