WO2014181633A1 - Dispositif de mesure d'onde acoustique, dispositif de reproduction d'image d'onde acoustique, procede de stockage de donnees et procede de reproduction d'image d'onde acoustique - Google Patents

Dispositif de mesure d'onde acoustique, dispositif de reproduction d'image d'onde acoustique, procede de stockage de donnees et procede de reproduction d'image d'onde acoustique Download PDF

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Publication number
WO2014181633A1
WO2014181633A1 PCT/JP2014/060430 JP2014060430W WO2014181633A1 WO 2014181633 A1 WO2014181633 A1 WO 2014181633A1 JP 2014060430 W JP2014060430 W JP 2014060430W WO 2014181633 A1 WO2014181633 A1 WO 2014181633A1
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Prior art keywords
data
acoustic wave
photoacoustic
reflected acoustic
reflected
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PCT/JP2014/060430
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English (en)
Japanese (ja)
Inventor
和弘 広田
白水　豪
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富士フイルム株式会社
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5292—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves using additional data, e.g. patient information, image labeling, acquisition parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0035—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4416—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5261—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from different diagnostic modalities, e.g. ultrasound and X-ray

Definitions

  • the present invention relates to an acoustic wave measuring apparatus that detects a photoacoustic wave generated due to light irradiation in a subject and a reflected acoustic wave with respect to a transmitted ultrasonic wave.
  • the present invention also relates to a data storage method in such an acoustic wave measuring apparatus.
  • An ultrasonic inspection method is known as a kind of image inspection method capable of non-invasively examining the state inside a living body.
  • an ultrasonic probe capable of transmitting and receiving ultrasonic waves is used.
  • the ultrasonic waves travel inside the living body and are reflected at the tissue interface.
  • the reflected ultrasound is received by the ultrasound probe, and the internal state can be imaged by calculating the distance based on the time it takes for the reflected ultrasound to return to the ultrasound probe. .
  • photoacoustic imaging in which the inside of a living body is imaged using the photoacoustic effect.
  • a living body is irradiated with pulsed laser light such as a laser pulse. Inside the living body, the living tissue absorbs the energy of the pulsed laser light, and ultrasonic waves (photoacoustic waves) are generated by adiabatic expansion due to the energy.
  • This photoacoustic wave is detected by an ultrasonic probe, etc., and the photoacoustic image is reconstructed based on the time from the irradiation of the pulsed laser light until the photoacoustic wave is detected by the ultrasonic probe. In vivo visualization based on waves is possible.
  • Patent Document 1 describes that both reflected ultrasonic waves and photoacoustic waves are detected and an ultrasonic image and a photoacoustic image are generated.
  • a detection signal of reflected ultrasonic waves and a detection signal of photoacoustic waves are stored in a reception memory, and each signal is read from the reception memory to generate an ultrasonic image and a photoacoustic image.
  • Patent Document 1 describes that header information is added to a photoacoustic wave detection signal and a reflected acoustic wave detection signal in a reception memory, and the header information is separated to separate them.
  • the generated ultrasonic image and the photoacoustic image are displayed so as to overlap with each other or be switched.
  • Japanese Patent Application Laid-Open No. H10-228667 only stores the reflected ultrasonic detection signal and the photoacoustic wave detection signal temporarily in the reception memory.
  • Patent Document 1 it is not considered that the reflected ultrasonic detection signal and the photoacoustic wave detection signal are stored in the auxiliary storage device and used later.
  • an object of the present invention is to provide an acoustic wave measurement device that stores photoacoustic data and reflected ultrasound data in an auxiliary storage device in a form that can be used later.
  • the present invention provides an acoustic wave for detecting a photoacoustic wave generated in a subject due to light emission to the subject and a reflected acoustic wave for the acoustic wave transmitted in the subject.
  • Detection means photoacoustic data based on the detected photoacoustic wave, and reflected acoustic wave data based on the detected reflected acoustic wave are stored in the auxiliary storage device, and the stored location of the stored photoacoustic data and reflected acoustic wave data
  • the present invention provides an acoustic wave measuring device comprising: data recording means for storing meta information including information indicating the above in association with photoacoustic data and reflected acoustic wave data in an auxiliary storage device.
  • the data recording means may record the meta information in a header of a file storing photoacoustic data and reflected acoustic wave data.
  • the data recording means may store the photoacoustic data and the reflected acoustic wave data in the same file.
  • the data recording means may store the photoacoustic data and the reflected acoustic wave data in different blocks of the file.
  • the information indicating the storage position of the photoacoustic data and the reflected acoustic wave data may include address information in the file.
  • the meta information may include information indicating the data structure of the stored photoacoustic data and reflected acoustic wave data.
  • the data recording means may store the photoacoustic data and the reflected acoustic wave data in a file in units of data blocks.
  • the information indicating the data structure includes the data block size and the data block for storing the photoacoustic data. And the block number of the data block for storing the reflected acoustic wave data.
  • the data recording means may store the photoacoustic data and the reflected acoustic wave data in different files.
  • the meta information may be stored in association with a file storing photoacoustic data and a file storing reflected acoustic wave data.
  • the meta information stored in association with the file storing the photoacoustic data may include identification information of the file storing the reflected acoustic wave data.
  • the meta information stored in association with the file storing the reflected acoustic wave data may include identification information of the file storing the photoacoustic data.
  • the meta information may further include information indicating the correspondence between the frames of the photoacoustic data and the reflected acoustic wave data.
  • the photoacoustic data and the reflected acoustic wave data may be stored in the auxiliary storage device in DICOM (Digital Imaging and Communications in Medicine) format.
  • DICOM Digital Imaging and Communications in Medicine
  • the meta information may be stored in the DICOM header.
  • the photoacoustic data may be a photoacoustic wave detection signal
  • the reflected acoustic wave data may be a reflected acoustic wave detection signal
  • the acoustic wave measuring device of the present invention includes a data reading means for reading out a photoacoustic wave detection signal and a reflected acoustic wave detection signal from an auxiliary storage device, and a photoacoustic wave detection signal and a reflected acoustic wave with reference to meta information.
  • Data separation means for separating the detection signal, photoacoustic image generation means for generating a photoacoustic image based on the detection signal of the photoacoustic wave, and reflection for generating a reflected acoustic wave image based on the detection signal of the reflected acoustic wave
  • a configuration further including acoustic wave image generation means and display control means for displaying at least one of a photoacoustic image and a reflected acoustic wave image on a display device.
  • photoacoustic images generated based on photoacoustic wave detection signals are used as photoacoustic data, and generated based on reflected acoustic wave detection signals.
  • the reflected acoustic wave image may be used as reflected acoustic wave data.
  • the acoustic wave measuring apparatus of the present invention includes a data reading unit that reads a photoacoustic image and a reflected acoustic wave image from an auxiliary storage device, and a data separating unit that separates the photoacoustic image and the reflected acoustic wave image with reference to meta information.
  • a configuration further comprising display control means for displaying at least one of the read photoacoustic image and reflected acoustic wave image on the display device.
  • the display control means may display the photoacoustic image and the reflected acoustic image superimposed, side by side, or switched.
  • the present invention also provides data reading means for reading out photoacoustic data and reflected acoustic wave data from an auxiliary storage device for storing photoacoustic data and reflected acoustic wave data, and photoacoustic data and reflected acoustics stored in the auxiliary storage device.
  • the read photoacoustic data and the reflected acoustic wave data are separated based on the meta information stored in the auxiliary storage device in association with the photoacoustic data and the reflected acoustic wave data, including information indicating the storage position of the wave data.
  • Photoacoustic image generation means for generating a photoacoustic image based on photoacoustic data
  • reflected acoustic wave image generation means for generating a reflected acoustic wave image based on reflected acoustic wave data
  • photoacoustic image reproducing device comprising display control means for displaying at least one of reflected acoustic wave images on a display device.
  • the present invention further includes a step of detecting a photoacoustic wave generated in the subject due to light emission to the subject, a step of detecting a reflected acoustic wave with respect to the acoustic wave transmitted in the subject, and a detection Storing the photoacoustic data based on the recorded photoacoustic wave and the reflected acoustic wave data based on the detected reflected acoustic wave in the auxiliary storage device, and information indicating the storage positions of the stored photoacoustic data and the reflected acoustic wave data And storing the meta information including the information in the auxiliary storage device in association with the photoacoustic data and the reflected acoustic wave data.
  • the present invention includes a step of reading photoacoustic data and reflected acoustic wave data from an auxiliary storage device that stores photoacoustic data and reflected acoustic wave data, and storing photoacoustic data and reflected acoustic wave data stored in the auxiliary storage device.
  • a step of generating a photoacoustic image based on the photoacoustic data, a step of generating a reflected acoustic wave image based on the reflected acoustic wave data, and at least one of the photoacoustic image and the reflected acoustic wave image are displayed on a display device.
  • an acoustic wave image reproduction method including steps.
  • the photoacoustic data based on the detected photoacoustic wave and the reflected acoustic wave data based on the detected reflected acoustic wave are stored in the auxiliary storage device. Further, meta information including information indicating the storage position of the stored photoacoustic data and reflected acoustic wave data is stored in the auxiliary storage device in association with the photoacoustic data and reflected acoustic wave data.
  • the meta information it is possible to separate the photoacoustic data and the reflected acoustic wave data, and the photoacoustic data and the reflected ultrasonic data are respectively stored in the auxiliary storage device in a manner that can be used later. I can remember.
  • the block diagram which shows the file of the photoacoustic data and the file of reflected ultrasound data which are memorize
  • FIG. 1 shows an acoustic wave measuring apparatus according to a first embodiment of the present invention.
  • the acoustic wave measurement device (acoustic wave image generation device) 10 includes an ultrasonic probe (probe) 11, an ultrasonic unit 12, and a light source (laser unit) 13.
  • an ultrasonic wave is used as an acoustic wave.
  • the ultrasonic wave is not limited to an ultrasonic wave, and is audible as long as an appropriate frequency is selected in accordance with an object to be examined and measurement conditions.
  • An acoustic wave having a frequency may be used.
  • the light source 13 emits light irradiated on the subject.
  • the light source 13 is configured as a laser light source, for example.
  • the light source 13 includes a solid-state laser using, for example, YAG (yttrium, aluminum, garnet), Nd: YAG (neodymium YAG), alexandrite, or the like.
  • the light source 13 includes a flash lamp 39 that excites a laser medium (not shown) and a Q switch 38 that controls laser oscillation. What is necessary is just to set suitably the wavelength of the light irradiated to a subject according to an observation object.
  • the light emitted from the light source 13 is guided to the probe 11 using light guide means such as an optical fiber, and is emitted from the probe 11 toward the subject.
  • the light source 13 is not limited to a flash lamp-pumped solid-state laser, and may be a laser diode (LD) -pumped solid-state laser. Alternatively, a laser different from a solid-state laser, such as a semiconductor laser, may be used.
  • LD laser diode
  • the probe 11 has an ultrasonic transmission unit that outputs (transmits) ultrasonic waves to the subject, and an ultrasonic detection unit (acoustic wave detection means) that detects (receives) ultrasonic waves from the subject.
  • the ultrasonic detection element of the ultrasonic detection unit may also serve as the ultrasonic transmission element of the ultrasonic transmission unit.
  • one ultrasonic transducer (element) may be used for both transmission and detection of ultrasonic waves.
  • the probe 11 has, for example, a plurality of ultrasonic transducers arranged one-dimensionally, outputs ultrasonic waves from the ultrasonic transducers, and detects reflected ultrasonic waves with respect to the output ultrasonic waves. .
  • the probe 11 detects photoacoustic waves generated when the measurement object in the subject absorbs light from the light source 13 using a plurality of ultrasonic transducers.
  • the ultrasonic unit 12 includes a reception circuit 21, an AD conversion unit 22, a reception memory 23, a data separation unit 24, a photoacoustic image reconstruction unit 25, a detection / logarithm conversion unit 26, a photoacoustic image construction unit 27, an ultrasonic image reconstruction unit.
  • Configuration means 28, detection / logarithmic conversion means 29, ultrasonic image construction means 30, image synthesis means 31, trigger control circuit 32, sampling control circuit 33, control means 34, transmission control circuit 35, data recording means 36, and auxiliary storage A device 37 is included.
  • the control means 34 controls each part in the ultrasonic unit 12.
  • the functions of each means included in the ultrasonic unit 12 are realized by, for example, a computer microprocessor operating according to a predetermined program.
  • the receiving circuit 21 receives a photoacoustic wave detection signal (photoacoustic signal) and a reflected ultrasonic detection signal (reflected ultrasonic signal) detected by the probe 11.
  • the AD conversion unit 22 is a sampling unit that samples the photoacoustic signal and the reflected ultrasonic signal received by the receiving circuit 21 and converts them into a digital signal.
  • the AD conversion means 22 samples the reflected ultrasonic signal at a predetermined sampling period in synchronization with, for example, an AD clock signal.
  • the trigger control circuit 32 outputs a flash lamp trigger signal and a Q switch trigger signal to the light source 13, and instructs the light source 13 to emit light.
  • the trigger control circuit 32 outputs a flash lamp trigger signal
  • the light source 13 turns on the flash lamp 39 and excites the laser medium.
  • the trigger control circuit 32 outputs a Q switch trigger signal.
  • the Q switch 38 is turned on when a Q switch trigger signal is received, and emits laser light from the light source 13.
  • the time required from when the flash lamp 39 is turned on until the laser medium is sufficiently excited can be estimated from the characteristics of the laser medium.
  • the Q switch 38 may be turned on after the laser medium is sufficiently excited in the light source 13. In that case, a signal indicating that the Q switch 38 is turned on may be notified to the ultrasonic unit 12 side.
  • the trigger control circuit 32 outputs an ultrasonic trigger signal that instructs ultrasonic transmission to the transmission control circuit 35.
  • the transmission control circuit 35 transmits an ultrasonic wave from the probe 11.
  • the trigger control circuit 32 causes the light emission from the light source 13 and the ultrasonic transmission to be executed at different times. For example, when acquiring a photoacoustic image, the trigger control circuit 32 outputs a flash lamp trigger signal and a Q switch trigger signal. By outputting the flash lamp trigger signal and the Q switch trigger signal, the subject is irradiated with laser light and photoacoustic waves are detected. On the other hand, when acquiring a reflected ultrasound image, an ultrasound trigger signal is output to an element that performs transmission / reception, and ultrasound transmission to the subject and reflected ultrasound detection are performed.
  • the sampling control circuit 33 outputs a sampling trigger signal for instructing the AD conversion means 22 to start sampling. For example, the sampling control circuit 33 outputs the sampling trigger signal in synchronization with the timing at which the trigger control circuit 32 outputs the Q switch trigger signal.
  • the AD conversion means 22 starts sampling the photoacoustic signal output from the probe 11.
  • the sampling control circuit 33 outputs a sampling trigger signal in synchronization with the timing at which the trigger control circuit 32 outputs an ultrasonic trigger signal.
  • the AD conversion means 22 starts sampling the reflected ultrasonic signal output from the probe 11.
  • the AD conversion means 22 stores the sampled photoacoustic signal and reflected ultrasonic signal in the reception memory 23.
  • the reception memory 23 for example, a semiconductor memory device can be used. Alternatively, other storage devices such as a magnetic storage device may be used for the reception memory 23.
  • the data separation unit 24 separates the photoacoustic signal and the reflected ultrasonic signal. The data separation unit 24 passes the separated photoacoustic signal to the photoacoustic image reconstruction unit 25 and passes the reflected ultrasonic signal to the ultrasonic image reconstruction unit 28.
  • the photoacoustic image reconstruction unit 25 receives a photoacoustic signal from the data separation unit 24.
  • the photoacoustic image reconstruction unit 25 generates data of each line of the photoacoustic image that is a tomographic image based on the photoacoustic signal.
  • the photoacoustic image reconstruction unit 25 reconstructs the data detected by the 64 ultrasonic transducers of the probe 11 for each line with a delay time corresponding to the position of the ultrasonic transducer. (Delayed addition method).
  • the photoacoustic image reconstruction means 25 may perform reconstruction by the CBP method (Circular Back Projection) instead of the delay addition method.
  • the photoacoustic image reconstruction unit 25 may perform reconstruction using a Fourier transform method.
  • the reconstructed photoacoustic signal can be regarded as a photoacoustic image.
  • the detection / logarithm conversion unit 26 generates an envelope of data of each line output from the photoacoustic image reconstruction unit 25, and logarithmically converts the envelope to widen the dynamic range.
  • the photoacoustic image construction unit 27 generates a photoacoustic image based on the data of each line subjected to logarithmic transformation.
  • the photoacoustic image reconstruction unit 25, the detection / logarithm conversion unit 26, and the photoacoustic image construction unit 27 constitute a photoacoustic image generation unit that generates a photoacoustic image based on the photoacoustic signal.
  • the ultrasonic image reconstruction unit 28 receives the reflected ultrasonic signal from the data separation unit 24.
  • the ultrasonic image reconstruction unit 28 generates data of each line of the ultrasonic image that is a tomographic image based on the reflected ultrasonic signal.
  • the detection / logarithm conversion means 29 generates an envelope of the data of each line output from the ultrasonic image reconstruction means 28, and logarithmically transforms the envelope to widen the dynamic range.
  • the ultrasonic image construction unit 30 generates an ultrasonic image based on the data of each line subjected to logarithmic transformation.
  • the ultrasonic image reconstruction unit 28, the detection / logarithm conversion unit 29, and the ultrasonic image construction unit 30 constitute an ultrasonic image generation unit that generates an ultrasonic image based on the reflected ultrasonic signal.
  • the sampling clock of the AD conversion means 22 at the time of reflected ultrasonic detection may be lowered to half of the sampling clock at the time of photoacoustic wave detection.
  • the sampled reflected acoustic signal may be resampled to 1 ⁇ 2, and the reflected acoustic signal may be compressed to 1 ⁇ 2 in the time axis direction.
  • the image composition means 31 is a display control means for displaying at least one of a photoacoustic image and a reflected acoustic wave image on the image display means 14.
  • the image composition unit 31 synthesizes the photoacoustic image generated by the photoacoustic image construction unit 27 and the ultrasonic image generated by the ultrasonic image construction unit 30 when displaying an image.
  • the image composition unit 31 performs image composition by superimposing a photoacoustic image on an ultrasonic image, for example.
  • the image synthesizing unit 31 displays the synthesized image on the screen of an image display unit (image display device) 14 such as a display monitor. Any one of the photoacoustic image and the ultrasonic image may be displayed on the image display unit 14 without performing image synthesis. Alternatively, the photoacoustic image and the ultrasonic image may be displayed side by side.
  • the data recording unit 36 stores the photoacoustic data based on the photoacoustic wave detected by the probe 11 and the reflected ultrasonic data based on the detected reflected acoustic wave in the auxiliary storage device 37.
  • the auxiliary storage device 37 for example, a hard disk drive or an optical drive device can be used.
  • the data recording unit 36 stores photoacoustic data and reflected ultrasonic data in the same file.
  • the photoacoustic data is a photoacoustic signal output from the probe 11, and the reflected ultrasonic data is a reflected ultrasonic signal output from the probe 11.
  • the data recording means 36 reads the photoacoustic signal and the reflected ultrasonic signal from the reception memory 23 and stores them in the auxiliary storage device 37.
  • the data recording unit 36 associates meta information including information indicating the storage positions of the photoacoustic data and the reflected ultrasonic data stored in the auxiliary storage device 37 with the photoacoustic data and the reflected acoustic wave data, and the auxiliary storage device 37.
  • the auxiliary storage device that stores the photoacoustic data and the reflected ultrasonic data and the auxiliary storage device that stores the meta information are not necessarily the same, and an auxiliary storage device that stores the photoacoustic data and the reflected ultrasonic data. May store the meta information in a different auxiliary storage device.
  • the data recording unit 36 records meta information in the header of a file that stores photoacoustic data and reflected ultrasonic data.
  • address information in the file is used as information indicating the storage position of the photoacoustic data and the reflected ultrasonic data.
  • the data recording means 36 also serves as data reading means for reading out photoacoustic data and reflected ultrasonic data from the auxiliary storage device 37.
  • the data recording unit 36 reads out the photoacoustic signal and the reflected ultrasonic signal from the auxiliary storage device 37 and passes them to the data separation unit 24.
  • the data separation unit 24 separates the photoacoustic signal and the reflected ultrasonic signal with reference to the meta information.
  • the data separation unit 24 passes the photoacoustic signal read from the auxiliary storage device 37 to the photoacoustic image reconstruction unit 25 constituting the photoacoustic image generation unit. Further, the reflected ultrasonic signal read from the auxiliary storage device 37 is transferred to the ultrasonic image reconstruction means 28 constituting the ultrasonic image generation means.
  • the photoacoustic image generation unit and the ultrasonic image generation unit generate a photoacoustic image and an ultrasonic image based on the photoacoustic signal and the reflected ultrasonic signal read from the auxiliary storage device 37, respectively.
  • Fig. 2 shows the data acquisition sequence.
  • the mode “US” corresponds to detection of reflected ultrasonic waves
  • the mode “PA” corresponds to detection of photoacoustic waves.
  • the probe 11 has, for example, 128 ultrasonic transducers arranged one-dimensionally. It is assumed that the AD conversion means 22 can sample signals for 64 elements at a time. The ultrasonic image is generated by reconstructing line by line while shifting the ultrasonic transducer connected to the AD conversion unit 22 element by element. Image data for one line can be obtained by reconstructing the reflected ultrasonic signal detected by the ultrasonic transducer of 64 elements for each line.
  • the reflected ultrasonic signals detected by the ultrasonic transducers having a number smaller than 64 elements are reconstructed.
  • the photoacoustic image is reconstructed after dividing all 128 elements into two areas of 64 elements, and performing light emission and photoacoustic wave detection in each area.
  • transmission of ultrasonic waves and detection of reflected ultrasonic waves are started from the first line of the probe 11, and the range of elements (opening elements) that perform transmission of ultrasonic waves and detection of reflected ultrasonic waves is shifted line by line.
  • the range of elements (opening elements) that perform transmission of ultrasonic waves and detection of reflected ultrasonic waves is shifted line by line.
  • light emission to the subject and detection of the photoacoustic wave are performed in the first area.
  • light emission to the subject and detection of the photoacoustic wave are performed in the second area.
  • FIG. 3 shows the structure of the photoacoustic data and reflected ultrasonic data files stored in the auxiliary storage device 37.
  • a file 50 for storing photoacoustic data and reflected ultrasonic data includes a header 51 and a data body 52.
  • the header 51 is a part for storing various information related to the file 50
  • the data body 52 is a part for storing binary data.
  • photoacoustic data and reflected ultrasonic data are stored in the data body 52.
  • the data body 52 can store photoacoustic data and reflected ultrasonic data for a plurality of frames.
  • photoacoustic signals and reflected ultrasonic signals are stored for each frame, for example, in the arrangement order according to the data acquisition sequence shown in FIG.
  • the number of samples per element of the photoacoustic signal and the reflected ultrasonic signal is, for example, 2048 samples, and the data amount per sample is 2 bytes. In this case, the data amount per element is 4 kbytes.
  • the photoacoustic signal detected by 64 elements from 1ch to 64ch is stored in the data (PA Area1) of the first area of the photoacoustic signal.
  • FIG. 4 shows an example of the header 51 information.
  • address information in a file of photoacoustic data and reflected ultrasonic data is stored as meta information.
  • the meta information includes the start address of each frame, the start address of each line of reflected ultrasound data within the frame, and the start address of each area of photoacoustic data within the frame.
  • the start address of each frame is described as a relative address from the start address of the data body 52 (FIG. 3).
  • the start address of each area of the photoacoustic data in the frame and each line of the reflected ultrasound data is described by a relative address from the start address of the frame.
  • Fig. 5 shows a modification of the header information.
  • information indicating the data structure of the photoacoustic data and the reflected acoustic wave data stored in the file may be stored as meta information instead of the address information in the file of the photoacoustic data and the reflected ultrasonic data.
  • the data recording means 36 (FIG. 1) stores photoacoustic data and reflected acoustic wave data in a file in units of data blocks. For example, 4 kbytes is set as the size of one data block, and a photoacoustic signal corresponding to each area or a reflected ultrasonic signal corresponding to each line is stored in each data block.
  • the size of the data block, the block number of the data block storing the photoacoustic data, and the block number of the data block storing the reflected acoustic wave data are stored in the header 51a as meta information. That's fine.
  • photoacoustic signals two areas
  • reflected ultrasonic signals (128 lines) are stored in a total of 130 data blocks.
  • data blocks for storing reflected acoustic wave data are data blocks having block numbers 1, 2,..., 64, 66, 67,.
  • Information that the data block is a data block having block numbers 65 and 130 is stored.
  • the photoacoustic wave and the reflected ultrasonic wave are continuously detected, and the photoacoustic image and the ultrasonic image are displayed on the image display unit 14 as a moving image.
  • the user instructs the start of data storage by operating the console at an arbitrary timing.
  • the data recording unit 36 stores the sampling data of the photoacoustic signal and the reflected ultrasonic signal in the auxiliary storage device 37.
  • the data recording unit 36 generates meta information indicating the storage position of the photoacoustic data and the reflected ultrasonic data, and stores the generated meta information in the file header.
  • meta information may be generated and added to the file header to create a new file.
  • the photoacoustic signal and the reflected ultrasonic signal are stored in the auxiliary storage device 37.
  • meta information including information indicating the positions of the photoacoustic signal and the reflected ultrasonic signal is stored in the header of the file. Even if photoacoustic signals and reflected ultrasound signals are mixed in the data body part of the file, they can be separated by referring to the header, and the photoacoustic signals and reflected ultrasound signals stored in the auxiliary storage device Later use becomes possible.
  • the image displayed on the image display unit 14 is not stored in the auxiliary storage device 37, but the photoacoustic signal and the reflected ultrasonic signal output from the probe 11 are stored in the auxiliary storage device 37. .
  • the photoacoustic signal and the reflected ultrasonic signal as the image generation source in the auxiliary storage device 37, not only the image displayed when detecting the photoacoustic wave and the reflected ultrasonic wave, but also the ultrasonic image and the photoacoustic signal.
  • the display can be freely switched by a combination of images, and the image display can be performed by arbitrarily switching a single display of a photoacoustic image, a single display of an ultrasonic image, a superimposed display of both, or the like.
  • the configuration of the acoustic wave measurement device of the second embodiment is the same as the configuration of the acoustic wave measurement device 10 of the first embodiment shown in FIG.
  • the data recording unit 36 stores the photoacoustic data and the reflected ultrasonic data in the auxiliary storage device 37 in order according to the data acquisition sequence.
  • the data recording unit 36 stores the photoacoustic data and the reflected acoustic wave data in blocks in the same file. Other points may be the same as in the first embodiment.
  • FIG. 6 shows a file structure of photoacoustic data and reflected ultrasonic data stored in the auxiliary storage device 37 in the present embodiment.
  • the file 55 includes a header 56, a photoacoustic data block 57, and a reflected ultrasonic data block 58.
  • the photoacoustic data block 57 and the reflected ultrasonic data block 58 are the data body portion of the file 55.
  • the file 55 stores, for example, 100 frames of photoacoustic data and reflected ultrasonic data.
  • the photoacoustic wave and the reflected ultrasonic wave are detected by, for example, a data acquisition sequence shown in FIG.
  • the data recording unit 36 When storing the photoacoustic data and the reflected ultrasonic data in the auxiliary storage device 37, the data recording unit 36 rearranges the data so that the photoacoustic data and the reflected ultrasonic data are successively arranged in the file.
  • the data recording means 36 temporarily stores, for example, the photoacoustic data and the reflected ultrasonic data in the auxiliary storage device 37 in the form of a mixture of both as shown in FIG. You may change.
  • FIG. 7 shows an example of information of the header 56.
  • the start address of the photoacoustic data, the start address of the reflected ultrasound data, the data size of one line or one area, and the total number of frames are stored as meta information.
  • the start address of the photoacoustic data and the reflected ultrasound data is described as a relative address from the start address of the data body portion excluding the header 56.
  • the photoacoustic data and the reflected ultrasonic data can be separated from the file 55 (FIG. 6).
  • the photoacoustic data and the reflected ultrasonic data are stored separately in the same file.
  • a plurality of frames of photoacoustic data or reflected ultrasound data can be read as continuous data, and the readout time can be shortened.
  • Other effects are the same as those of the first embodiment.
  • the configuration of the acoustic wave measurement device of the present embodiment is the same as the configuration of the acoustic wave measurement device of the first embodiment shown in FIG.
  • the photoacoustic data and the reflected ultrasonic data are stored in the same file.
  • the photoacoustic data and the reflected ultrasonic data are stored separately in files.
  • the meta information is stored in association with a file storing photoacoustic data and a file storing reflected ultrasonic data.
  • FIG. 8 shows a photoacoustic data file and a reflected ultrasonic data file stored in the auxiliary storage device 37 in the present embodiment.
  • the file 60 is a file for storing photoacoustic data
  • the file 63 is a file for storing reflected ultrasound data.
  • the photoacoustic wave and the reflected ultrasonic wave are detected by, for example, a data acquisition sequence shown in FIG.
  • the file 60 includes a header 61 and a data body 62.
  • the header 61 includes meta information.
  • the data body 62 stores photoacoustic data corresponding to two areas for each frame.
  • the file 63 includes a header 64 and a data body 65.
  • the header 64 includes meta information.
  • the data body 65 stores reflected ultrasound data for 128 lines for each frame.
  • FIG. 9 shows an example of information of the headers 61 and 64.
  • identification information of a file 63 for storing the pair of reflected ultrasound data is stored as meta information.
  • identification information of the file 60 that stores the paired photoacoustic data is stored as meta information.
  • a file name can be used as the file identification information.
  • the header 61 includes the data size of one area of photoacoustic data, the start address of each frame, and the like.
  • the header 64 includes the data size of one line of reflected ultrasound data, the start address of each frame, and the like. The start address is described as a relative address from the start addresses of the data bodies 62 and 65.
  • both the photoacoustic wave and the reflected ultrasonic wave are not always detected.
  • the photoacoustic image and the ultrasonic image may have different frame rates, and the photoacoustic wave may be detected for one frame while the reflected ultrasonic wave is detected for two frames.
  • the detection of the photoacoustic wave may be temporarily stopped and only the reflected ultrasonic wave may be detected.
  • the headers 61 and 64 include information indicating the correspondence between the photoacoustic wave and the reflected ultrasonic wave between the frames.
  • the first frame of the photoacoustic data corresponds to the first frame of the reflected ultrasound data
  • the second frame of the photoacoustic data is 3 frames of the reflected ultrasound data.
  • Information that corresponds to the eye is stored.
  • the first frame of the reflected ultrasound data corresponds to the first frame of the photoacoustic data
  • the corresponding photoacoustic data is stored in the second frame of the reflected ultrasound data.
  • the information that the third frame of the reflected ultrasonic data corresponds to the second frame of the photoacoustic data is stored.
  • the photoacoustic image and the reflected ultrasonic image of the same frame can be displayed in a superimposed manner, in a line, or in a switched manner.
  • information indicating the correspondence between frames may be included in the meta information.
  • the photoacoustic data and the reflected ultrasonic data are stored in separate files.
  • a file storing photoacoustic data can be associated with a file storing reflected ultrasound data.
  • the images of the corresponding frames can be superimposed, switched, or displayed side by side. Other effects are the same as those of the first embodiment or the second embodiment.
  • FIG. 10 shows an acoustic wave measuring apparatus according to the fourth embodiment of the present invention.
  • the data recording unit 36 stores the photoacoustic signal and reflected ultrasonic signal sampling data output from the probe 11 in the auxiliary storage device 37 as photoacoustic data and reflected ultrasonic data.
  • the acoustic wave measuring device 10a stores the photoacoustic image generated based on the photoacoustic signal in the auxiliary storage device 37 as photoacoustic data, and the reflected acoustic wave generated based on the reflected acoustic wave signal. The image is stored in the auxiliary storage device 37 as reflected ultrasound data.
  • the data recording unit 36 auxiliary stores a photoacoustic signal (photoacoustic image) reconstructed by the photoacoustic image reconstruction unit 25 and subjected to detection / logarithmic conversion processing by the detection / logarithmic conversion unit 26 as photoacoustic data.
  • the photoacoustic data stored in the auxiliary storage device 37 is not limited to the image data after detection and logarithmic conversion, and the photoacoustic signal (photoacoustic image) reconstructed by the photoacoustic image reconstruction means 25 is supplemented. You may memorize
  • the data recording unit 36 converts the reflected ultrasonic signal (ultrasonic image) reconstructed by the ultrasonic image reconstructing unit 28 and subjected to the detection / logarithmic conversion processing by the detection / logarithmic conversion unit 29 to the reflected ultrasonic
  • the data is stored in the auxiliary storage device 37 as data.
  • the reflected ultrasound data stored in the auxiliary storage device 37 is not limited to the image data after detection and logarithmic conversion, and the reflected ultrasound signal (ultrasound image) reconstructed by the ultrasound image reconstruction means 28 is used. Alternatively, it may be stored in the auxiliary storage device 37. Alternatively, the ultrasonic image generated by the ultrasonic image constructing unit 30 may be stored in the auxiliary storage device 37 as reflected ultrasonic data.
  • the photoacoustic image and the reflected ultrasound image may be stored in the auxiliary storage device 37 in the form of being mixed in the same file as in the first embodiment, or similar to the second embodiment. Blocks may be stored separately in the same file.
  • the files may be divided and stored in the auxiliary storage device 37.
  • the photoacoustic image, the reflected ultrasound image, and the header are stored in a DICOM (Digital Imaging and communications in Medicine) format.
  • the data recording means 36 also serves as data reading means for reading out the photoacoustic image and the ultrasonic image from the auxiliary storage device 37.
  • the data recording unit 36 also serves as a data separating unit that separates the photoacoustic image and the ultrasonic image with reference to the meta information.
  • the data recording unit 36 passes the read photoacoustic image (after detection and logarithmic conversion) to the photoacoustic image construction unit 27. Further, the read ultrasonic image (after detection and logarithmic conversion) is passed to the ultrasonic image construction means 30.
  • the photoacoustic image generated by the photoacoustic image construction unit 27 and the ultrasonic image generated by the ultrasonic image construction unit 30 are displayed on the image display unit 14 via the image synthesis unit 31.
  • the acoustic wave measuring device 10a stores the photoacoustic image and the image data of the reflected ultrasonic image in the auxiliary storage device 37.
  • the amount of data stored in the auxiliary storage device 37 can be reduced as compared with the case of storing reflected ultrasound signals for 64 elements for each line, particularly for reflected ultrasound. Further, since it is not necessary to perform at least reconstruction at the time of data reproduction, it is possible to reduce processing load when data is read from the auxiliary storage device 37 and image display is performed. Other effects are the same as those of the first embodiment, the second embodiment, or the third embodiment.
  • the acoustic wave measuring device detects photoacoustic waves and reflected ultrasonic waves, stores data in the auxiliary storage device 37 based on the detected photoacoustic waves and reflected ultrasonic waves, and photoacoustics.
  • generation and display of an image and an ultrasonic image have been described, a portion for generating and displaying an image may be omitted from the acoustic wave measurement device. That is, the acoustic wave measurement device only needs to detect acoustic waves and store data, and generation and display of an image are not essential in the acoustic wave measurement device.
  • a portion for performing acoustic wave detection and data storage is omitted, photoacoustic data and reflected ultrasonic data are read from the auxiliary storage device 37, and image generation and display are performed (acoustic wave). Image reproducing device).
  • the acoustic wave measuring device of this invention As mentioned above, although this invention was demonstrated based on the preferable embodiment, the acoustic wave measuring device of this invention, The acoustic wave image reproduction device, the data storage method, and the sound image reproduction method are not limited to the above embodiment, and various modifications and changes from the configuration of the above embodiment are also applicable to the present invention. Included in the range.

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Abstract

Selon l'invention, dans un dispositif de mesure d'onde acoustique et un procédé de stockage de données, des données photoacoustiques et des données d'onde ultrasonore réfléchie sont stockées dans un dispositif de stockage auxiliaire de façon à permettre une utilisation ultérieure. De plus, dans le dispositif et le procédé de reproduction d'image d'onde acoustique, les données photoacoustiques et les données d'onde sonore réfléchie sont lues à partir du dispositif de stockage auxiliaire pour générer et afficher une image. Une sonde (11) détecte des ondes photoacoustiques générées à l'intérieur d'un sujet en raison d'une émission de lumière par rapport au sujet, ainsi que des ondes acoustiques réfléchies par rapport aux ondes acoustiques transmises au sujet. Un moyen d'enregistrement de données (36) stocke les données photoacoustiques sur la base des ondes photoacoustiques détectées, et les données d'onde acoustique réfléchie sur la base des ondes acoustiques réfléchies détectées dans le dispositif de stockage auxiliaire (37), et associe des meta-informations, qui comprennent des informations qui indiquent la position des données photoacoustiques et des données d'onde acoustique réfléchie stockées, aux données photoacoustiques et aux données d'onde acoustique réfléchie, et les stocke dans le dispositif de stockage auxiliaire.
PCT/JP2014/060430 2013-05-10 2014-04-10 Dispositif de mesure d'onde acoustique, dispositif de reproduction d'image d'onde acoustique, procede de stockage de donnees et procede de reproduction d'image d'onde acoustique WO2014181633A1 (fr)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018057695A (ja) * 2016-10-07 2018-04-12 キヤノン株式会社 画像表示システム、画像表示方法、及びプログラム
US11602329B2 (en) * 2016-10-07 2023-03-14 Canon Kabushiki Kaisha Control device, control method, control system, and non-transitory recording medium for superimpose display

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017145992A1 (fr) * 2016-02-22 2017-08-31 富士フイルム株式会社 Dispositif d'affichage et procédé d'affichage d'images d'onde acoustique
JP2018082923A (ja) * 2016-11-24 2018-05-31 キヤノン株式会社 情報処理装置、情報処理方法、情報処理システム及びプログラム

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009540904A (ja) * 2006-06-23 2009-11-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 光音響及び超音波合成撮像器のタイミング制御装置
JP2012005623A (ja) * 2010-06-24 2012-01-12 Fujifilm Corp 生体情報画像化装置及び方法
JP2012081004A (ja) * 2010-10-08 2012-04-26 Canon Inc 被検体情報処理装置
JP2012196428A (ja) * 2011-03-10 2012-10-18 Fujifilm Corp 断層画像生成装置及び方法
JP2012529328A (ja) * 2009-06-09 2012-11-22 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 記憶された画像を順序付けする装置及び方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009540904A (ja) * 2006-06-23 2009-11-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 光音響及び超音波合成撮像器のタイミング制御装置
JP2012529328A (ja) * 2009-06-09 2012-11-22 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 記憶された画像を順序付けする装置及び方法
JP2012005623A (ja) * 2010-06-24 2012-01-12 Fujifilm Corp 生体情報画像化装置及び方法
JP2012081004A (ja) * 2010-10-08 2012-04-26 Canon Inc 被検体情報処理装置
JP2012196428A (ja) * 2011-03-10 2012-10-18 Fujifilm Corp 断層画像生成装置及び方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018057695A (ja) * 2016-10-07 2018-04-12 キヤノン株式会社 画像表示システム、画像表示方法、及びプログラム
WO2018066563A1 (fr) * 2016-10-07 2018-04-12 Canon Kabushiki Kaisha Système d'affichage d'image, procédé d'affichage d'image et programme
US10997762B2 (en) 2016-10-07 2021-05-04 Canon Kabushiki Kaisha Image display system, image display method, and program
US11602329B2 (en) * 2016-10-07 2023-03-14 Canon Kabushiki Kaisha Control device, control method, control system, and non-transitory recording medium for superimpose display

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