WO2014179761A1 - Medical devices for implanting in a valve and associated methods - Google Patents

Medical devices for implanting in a valve and associated methods Download PDF

Info

Publication number
WO2014179761A1
WO2014179761A1 PCT/US2014/036686 US2014036686W WO2014179761A1 WO 2014179761 A1 WO2014179761 A1 WO 2014179761A1 US 2014036686 W US2014036686 W US 2014036686W WO 2014179761 A1 WO2014179761 A1 WO 2014179761A1
Authority
WO
WIPO (PCT)
Prior art keywords
valve
frame
visible
annulus
circumferential marking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2014/036686
Other languages
English (en)
French (fr)
Inventor
Matthew WESTON
Stella Kim
Carolyn C. Majkrzak
Michael GLOSS
Timothy GROEN
Behrooz NADIAN
Matthew Rust
Timothy Ryan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Inc
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Priority to JP2016512085A priority Critical patent/JP2016517748A/ja
Priority to EP14729789.9A priority patent/EP2991585B1/en
Publication of WO2014179761A1 publication Critical patent/WO2014179761A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418—Scaffolds therefor, e.g. support stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A61F2/2436—Deployment by retracting a sheath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0097—Visible markings, e.g. indicia

Definitions

  • Sinuses of the pulmonary trunk comprise the space at the origin of the pulmonary trunk between the dilated wall of the vessel and each cusp of the pulmonic valve.
  • Aortic sinuses or Valsalva sinuses comprise the space between the superior aspect of each cusp of the aortic valve and the dilated portion of the wall of the ascending aorta, immediately above each cusp.
  • eddy currents occurring within sinuses of V alsalva in the natural aortic root have been shown to be important in creating smooth, gradual and gentle closure of the aortic valve at the end of systole.
  • prosthetic heart valves having visible markings configured to be aligned with anatomical structures of a native valve, such as an annulus or a commissure.
  • the markings facilitate accurate implantation of the prosthetic valves at a proper depth or in a proper orientation.
  • FIGS. 2B and 2C al so show the narrowing diameter of the sinuses at both inflow end
  • FIG. 3 is a schematic representation of the geometry and relative dimensions of the valve sinus region. As shown in FIG.
  • Support posts 42 further comprise triangular shaped elements 52 extending on each side of proximal end 46 of the support post.
  • Triangular shaped elements 52 may be designed to serve as attachments sites for valve cuff 26 and may be designed in different shapes without losing their function.
  • the particular design of elements 52 shown in FIG, 6 is not critical to the attachment of valve cuff 26, and numerous other designs and shapes are contemplated and within the intended scope of the present disclosure ,
  • FIG. 7 is a side view illustrating replacement valve device 20 of FIG. 4, which once again includes replacement valve 22, valve support frame 24, and valve cuff 26.
  • valve 22 is secured at the proximal inflow end 31 by attachment to inflow rim 41 of valve frame 24 and at the distal outflow end 32 via commissural tabs 35 that are threaded through axially extending slots 44 formed in support posts 42.
  • outflow rim 43 of frame 24 is structured to be longitudinally displaced from the distal outflo w end 32 of valve leaflets 33 that reside within the lumen of the tubular valve frame 24. Thus, contact between valve leaflets 33 and frame 24 is avoided.

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
PCT/US2014/036686 2013-05-03 2014-05-02 Medical devices for implanting in a valve and associated methods Ceased WO2014179761A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2016512085A JP2016517748A (ja) 2013-05-03 2014-05-02 弁に埋め込むための医療デバイス及び関連の方法
EP14729789.9A EP2991585B1 (en) 2013-05-03 2014-05-02 Medical devices for implanting in a valve

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361819486P 2013-05-03 2013-05-03
US61/819,486 2013-05-03
US201461930851P 2014-01-23 2014-01-23
US61/930,851 2014-01-23

Publications (1)

Publication Number Publication Date
WO2014179761A1 true WO2014179761A1 (en) 2014-11-06

Family

ID=50933512

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/036686 Ceased WO2014179761A1 (en) 2013-05-03 2014-05-02 Medical devices for implanting in a valve and associated methods

Country Status (4)

Country Link
US (1) US20140330372A1 (https=)
EP (1) EP2991585B1 (https=)
JP (1) JP2016517748A (https=)
WO (1) WO2014179761A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12239709B2 (en) 2011-12-07 2025-03-04 Alnylam Pharmaceuticals, Inc. Biodegradable lipids for the delivery of active agents

Families Citing this family (163)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008513060A (ja) 2004-09-14 2008-05-01 エドワーズ ライフサイエンシーズ アーゲー 心臓弁逆流の処置のためのデバイスおよび方法
AU2004324043A1 (en) 2004-10-02 2006-04-20 Christoph Hans Huber Methods and devices for repair or replacement of heart valves or adjacent tissue without the need for full cardiopulmonary support
US20100312333A1 (en) 2009-04-29 2010-12-09 The Cleveland Clinic Foundation Apparatus and method for replacing a diseased cardiac valve
EP3167847B1 (en) 2005-11-10 2020-10-14 Edwards Lifesciences CardiAQ LLC Heart valve prosthesis
US9585743B2 (en) 2006-07-31 2017-03-07 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US9408607B2 (en) 2009-07-02 2016-08-09 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
WO2008016578A2 (en) 2006-07-31 2008-02-07 Cartledge Richard G Sealable endovascular implants and methods for their use
US9566178B2 (en) 2010-06-24 2017-02-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
BRPI0817708A2 (pt) 2007-09-26 2017-05-16 St Jude Medical válvula cardíaca protética, e, estrutura de lamela para a mesma.
EP2231070B1 (en) 2007-12-14 2013-05-22 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US20090276040A1 (en) 2008-05-01 2009-11-05 Edwards Lifesciences Corporation Device and method for replacing mitral valve
CA3272264A1 (en) 2008-06-06 2025-10-30 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
CN102292053A (zh) 2008-09-29 2011-12-21 卡迪尔克阀门技术公司 心脏瓣膜
US8790387B2 (en) 2008-10-10 2014-07-29 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
WO2010057262A1 (en) 2008-11-21 2010-05-27 Percutaneous Cardiovascular Solutions Pty Limited Heart valve prosthesis and method
AU2010236288A1 (en) 2009-04-15 2011-10-20 Cardiaq Valve Technologies, Inc. Vascular implant and delivery system
US8652203B2 (en) 2010-09-23 2014-02-18 Cardiaq Valve Technologies, Inc. Replacement heart valves, delivery devices and methods
US9730790B2 (en) 2009-09-29 2017-08-15 Edwards Lifesciences Cardiaq Llc Replacement valve and method
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8795354B2 (en) 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
EP3061422B1 (en) 2010-06-21 2021-11-03 Edwards Lifesciences CardiAQ LLC Replacement heart valve
PL3593762T3 (pl) 2010-10-05 2021-05-04 Edwards Lifesciences Corporation Zastawka protetyczna serca i urządzenie do wprowadzania
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US12502276B2 (en) 2011-05-16 2025-12-23 Edwards Lifesciences Corporation Inversion delivery device and method for a prosthesis
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
WO2013019756A2 (en) 2011-07-29 2013-02-07 Carnegie Mellon University Artificial valved conduits for cardiac reconstructive procedures and methods for their production
RU2474403C1 (ru) * 2011-09-06 2013-02-10 Закрытое Акционерное Общество Научно-Производственное Предприятие "Мединж" Клапаносодержащий протез корня аорты
US12364596B2 (en) 2011-10-21 2025-07-22 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US9827093B2 (en) 2011-10-21 2017-11-28 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
EP3424469A1 (en) 2012-02-22 2019-01-09 Syntheon TAVR, LLC Actively controllable stent, stent graft and heart valve
EP4162902A1 (en) 2012-11-21 2023-04-12 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic heart valves
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
CA2904715C (en) 2013-03-08 2022-07-26 Carnegie Mellon University Expandable implantable fluoropolymer conduit
US20140277427A1 (en) 2013-03-14 2014-09-18 Cardiaq Valve Technologies, Inc. Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9730791B2 (en) 2013-03-14 2017-08-15 Edwards Lifesciences Cardiaq Llc Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
SG10202103500PA (en) 2013-08-12 2021-05-28 Mitral Valve Tech Sarl Apparatus and methods for implanting a replacement heart valve
US10052198B2 (en) 2013-08-14 2018-08-21 Mitral Valve Technologies Sarl Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device
CA2920865C (en) 2013-08-14 2023-06-06 Mitral Valve Technologies Sarl Replacement heart valve apparatus and methods
CA2934975A1 (en) 2013-11-11 2015-05-14 Edwards Lifesciences Cardiaq Llc Systems and methods for manufacturing a stent frame
US10098734B2 (en) 2013-12-05 2018-10-16 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
CA2938614C (en) 2014-02-21 2024-01-23 Edwards Lifesciences Cardiaq Llc Delivery device for controlled deployement of a replacement valve
CA3189691A1 (en) 2014-02-21 2015-08-27 Mitral Valve Technologies Sarl Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device
USD755384S1 (en) 2014-03-05 2016-05-03 Edwards Lifesciences Cardiaq Llc Stent
US20150328000A1 (en) 2014-05-19 2015-11-19 Cardiaq Valve Technologies, Inc. Replacement mitral valve with annular flap
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US10016272B2 (en) 2014-09-12 2018-07-10 Mitral Valve Technologies Sarl Mitral repair and replacement devices and methods
RU2017114607A (ru) 2014-09-28 2018-10-29 Кардиокинетикс, Инк. Устройства для терапии нарушений функции сердца
CN106999281B (zh) 2014-11-26 2020-05-05 爱德华兹生命科学公司 经导管人工心脏瓣膜和递送系统
US10039637B2 (en) 2015-02-11 2018-08-07 Edwards Lifesciences Corporation Heart valve docking devices and implanting methods
EP3725243A1 (en) 2015-03-20 2020-10-21 Cardiokinetix, Inc. Methods for preparing the delivery of an implantable device
US12194256B2 (en) 2015-04-10 2025-01-14 Edwards Lifesciences Corporation Expandable sheath
US10327896B2 (en) 2015-04-10 2019-06-25 Edwards Lifesciences Corporation Expandable sheath with elastomeric cross sectional portions
US10792471B2 (en) 2015-04-10 2020-10-06 Edwards Lifesciences Corporation Expandable sheath
US10441416B2 (en) 2015-04-21 2019-10-15 Edwards Lifesciences Corporation Percutaneous mitral valve replacement device
US10376363B2 (en) 2015-04-30 2019-08-13 Edwards Lifesciences Cardiaq Llc Replacement mitral valve, delivery system for replacement mitral valve and methods of use
CA2990872C (en) 2015-06-22 2022-03-22 Edwards Lifescience Cardiaq Llc Actively controllable heart valve implant and methods of controlling same
US10092400B2 (en) 2015-06-23 2018-10-09 Edwards Lifesciences Cardiaq Llc Systems and methods for anchoring and sealing a prosthetic heart valve
US10232082B2 (en) 2015-06-29 2019-03-19 480 Biomedical, Inc. Implantable scaffolds for treatment of sinusitis
EP3313330A4 (en) 2015-06-29 2019-03-20 480 Biomedical, Inc. CHARGING AND DISPENSING SYSTEMS
EP4233873A3 (en) 2015-06-29 2023-10-18 Lyra Therapeutics, Inc. Implantable scaffolds for treatment of sinusitis
US9974650B2 (en) 2015-07-14 2018-05-22 Edwards Lifesciences Corporation Prosthetic heart valve
US10575951B2 (en) 2015-08-26 2020-03-03 Edwards Lifesciences Cardiaq Llc Delivery device and methods of use for transapical delivery of replacement mitral valve
US10117744B2 (en) 2015-08-26 2018-11-06 Edwards Lifesciences Cardiaq Llc Replacement heart valves and methods of delivery
US10350066B2 (en) 2015-08-28 2019-07-16 Edwards Lifesciences Cardiaq Llc Steerable delivery system for replacement mitral valve and methods of use
US10314703B2 (en) 2015-09-21 2019-06-11 Edwards Lifesciences Corporation Cylindrical implant and balloon
US10973664B2 (en) 2015-12-30 2021-04-13 Lyra Therapeutics, Inc. Scaffold loading and delivery systems
US10179043B2 (en) 2016-02-12 2019-01-15 Edwards Lifesciences Corporation Prosthetic heart valve having multi-level sealing member
WO2017151900A1 (en) * 2016-03-02 2017-09-08 Peca Labs, Inc. Expandable implantable conduit
WO2017165842A1 (en) 2016-03-24 2017-09-28 Edwards Lifesciences Corporation Delivery system for prosthetic heart valve
USD815744S1 (en) 2016-04-28 2018-04-17 Edwards Lifesciences Cardiaq Llc Valve frame for a delivery system
US10350062B2 (en) 2016-07-21 2019-07-16 Edwards Lifesciences Corporation Replacement heart valve prosthesis
US11096781B2 (en) 2016-08-01 2021-08-24 Edwards Lifesciences Corporation Prosthetic heart valve
US10646340B2 (en) 2016-08-19 2020-05-12 Edwards Lifesciences Corporation Steerable delivery system for replacement mitral valve
CN114569289A (zh) 2016-08-26 2022-06-03 爱德华兹生命科学公司 多部分置换心脏瓣膜假体
US10575944B2 (en) 2016-09-22 2020-03-03 Edwards Lifesciences Corporation Prosthetic heart valve with reduced stitching
US10631979B2 (en) 2016-10-10 2020-04-28 Peca Labs, Inc. Transcatheter stent and valve assembly
US10758348B2 (en) 2016-11-02 2020-09-01 Edwards Lifesciences Corporation Supra and sub-annular mitral valve delivery system
US10463484B2 (en) 2016-11-17 2019-11-05 Edwards Lifesciences Corporation Prosthetic heart valve having leaflet inflow below frame
US10973631B2 (en) 2016-11-17 2021-04-13 Edwards Lifesciences Corporation Crimping accessory device for a prosthetic valve
US10603165B2 (en) 2016-12-06 2020-03-31 Edwards Lifesciences Corporation Mechanically expanding heart valve and delivery apparatus therefor
US11013600B2 (en) 2017-01-23 2021-05-25 Edwards Lifesciences Corporation Covered prosthetic heart valve
US11654023B2 (en) 2017-01-23 2023-05-23 Edwards Lifesciences Corporation Covered prosthetic heart valve
US11185406B2 (en) 2017-01-23 2021-11-30 Edwards Lifesciences Corporation Covered prosthetic heart valve
CN110392557A (zh) * 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 心脏瓣膜模拟
US10201639B2 (en) 2017-05-01 2019-02-12 480 Biomedical, Inc. Drug-eluting medical implants
US11135056B2 (en) 2017-05-15 2021-10-05 Edwards Lifesciences Corporation Devices and methods of commissure formation for prosthetic heart valve
EP4427706A3 (en) 2017-05-22 2024-12-04 Edwards Lifesciences Corporation Valve anchor and installation method
US12064341B2 (en) 2017-05-31 2024-08-20 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US11026785B2 (en) 2017-06-05 2021-06-08 Edwards Lifesciences Corporation Mechanically expandable heart valve
US10869759B2 (en) 2017-06-05 2020-12-22 Edwards Lifesciences Corporation Mechanically expandable heart valve
EP3648708A4 (en) 2017-07-06 2021-03-31 Edwards Lifesciences Corporation CONTROLLED DISPENSING SYSTEM AND COMPONENTS
US10918473B2 (en) 2017-07-18 2021-02-16 Edwards Lifesciences Corporation Transcatheter heart valve storage container and crimping mechanism
MY204938A (en) 2017-08-11 2024-09-23 Edwards Lifesciences Corp Sealing element for prosthetic heart valve
US11083575B2 (en) 2017-08-14 2021-08-10 Edwards Lifesciences Corporation Heart valve frame design with non-uniform struts
US10932903B2 (en) 2017-08-15 2021-03-02 Edwards Lifesciences Corporation Skirt assembly for implantable prosthetic valve
US10898319B2 (en) 2017-08-17 2021-01-26 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10973628B2 (en) 2017-08-18 2021-04-13 Edwards Lifesciences Corporation Pericardial sealing member for prosthetic heart valve
US10722353B2 (en) 2017-08-21 2020-07-28 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10973629B2 (en) 2017-09-06 2021-04-13 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US11147667B2 (en) 2017-09-08 2021-10-19 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
EP3720390B1 (en) 2018-01-25 2024-05-01 Edwards Lifesciences Corporation Delivery system for aided replacement valve recapture and repositioning post- deployment
US11051934B2 (en) 2018-02-28 2021-07-06 Edwards Lifesciences Corporation Prosthetic mitral valve with improved anchors and seal
WO2019195860A2 (en) 2018-04-04 2019-10-10 Vdyne, Llc Devices and methods for anchoring transcatheter heart valve
US11318011B2 (en) 2018-04-27 2022-05-03 Edwards Lifesciences Corporation Mechanically expandable heart valve with leaflet clamps
US12161551B2 (en) 2018-08-30 2024-12-10 Edwards Lifesciences Corporation Systems and methods for sizing and implanting prosthetic heart valves
US11071627B2 (en) 2018-10-18 2021-07-27 Vdyne, Inc. Orthogonally delivered transcatheter heart valve frame for valve in valve prosthesis
US11278437B2 (en) 2018-12-08 2022-03-22 Vdyne, Inc. Compression capable annular frames for side delivery of transcatheter heart valve replacement
US10321995B1 (en) 2018-09-20 2019-06-18 Vdyne, Llc Orthogonally delivered transcatheter heart valve replacement
US11344413B2 (en) 2018-09-20 2022-05-31 Vdyne, Inc. Transcatheter deliverable prosthetic heart valves and methods of delivery
US12186187B2 (en) 2018-09-20 2025-01-07 Vdyne, Inc. Transcatheter deliverable prosthetic heart valves and methods of delivery
US10595994B1 (en) 2018-09-20 2020-03-24 Vdyne, Llc Side-delivered transcatheter heart valve replacement
US12310847B2 (en) 2018-10-19 2025-05-27 Edwards Lifesciences Corporation Prosthetic heart valve having non-cylindrical frame
JP7507755B2 (ja) 2018-10-19 2024-06-28 エドワーズ ライフサイエンシーズ コーポレイション 非円筒状のフレームを有する人工心臓弁
US11109969B2 (en) 2018-10-22 2021-09-07 Vdyne, Inc. Guidewire delivery of transcatheter heart valve
JP7525503B2 (ja) 2018-10-30 2024-07-30 エドワーズ ライフサイエンシーズ コーポレイション 人工弁送達アセンブリ
CR20210226A (es) 2018-10-30 2021-10-01 Edwards Lifesciences Corp Control de diámetro de válvula y fuerza de una válvula cardiaca protésica
EP3890656A1 (en) 2018-12-06 2021-10-13 Edwards Lifesciences Corporation Mechanically expandable prosthetic heart valve and delivery apparatus
US11253359B2 (en) 2018-12-20 2022-02-22 Vdyne, Inc. Proximal tab for side-delivered transcatheter heart valves and methods of delivery
WO2020146842A1 (en) 2019-01-10 2020-07-16 Vdyne, Llc Anchor hook for side-delivery transcatheter heart valve prosthesis
JP2022517423A (ja) 2019-01-17 2022-03-08 エドワーズ ライフサイエンシーズ コーポレイション 人工弁用のフレーム
US11273032B2 (en) 2019-01-26 2022-03-15 Vdyne, Inc. Collapsible inner flow control component for side-deliverable transcatheter heart valve prosthesis
US11185409B2 (en) 2019-01-26 2021-11-30 Vdyne, Inc. Collapsible inner flow control component for side-delivered transcatheter heart valve prosthesis
CN113613594B (zh) 2019-01-28 2024-11-26 爱德华兹生命科学公司 假体瓣膜
WO2020163031A1 (en) 2019-02-04 2020-08-13 Edwards Lifesciences Corporation Guide wire apparatuses and methods
CN113613596B (zh) 2019-02-13 2024-11-12 爱德华兹生命科学公司 具有非均匀支柱的心脏瓣膜框架设计
JP7541023B2 (ja) 2019-03-04 2024-08-27 エドワーズ ライフサイエンシーズ コーポレイション 人工弁のための交連部取付
EP4729034A2 (en) 2019-03-05 2026-04-22 VDyne, Inc. Tricuspid regurgitation control devices for orthogonal transcatheter heart valve prosthesis
US11076956B2 (en) 2019-03-14 2021-08-03 Vdyne, Inc. Proximal, distal, and anterior anchoring tabs for side-delivered transcatheter mitral valve prosthesis
US11173027B2 (en) 2019-03-14 2021-11-16 Vdyne, Inc. Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same
CN113873973B (zh) 2019-03-26 2023-12-22 爱德华兹生命科学公司 假体心脏瓣膜
EP3946159A1 (en) 2019-03-27 2022-02-09 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
CR20210533A (es) 2019-04-11 2022-03-04 Edwards Lifesciences Corp Método de montaje de una válvula cardíaca protésica
JP7381601B2 (ja) 2019-04-12 2023-11-15 エドワーズ ライフサイエンシーズ コーポレイション マルチパートフレーム及び関連するレジリエントブリッジ特徴部を備えた弁
WO2020219459A1 (en) 2019-04-23 2020-10-29 Edwards Lifesciences Corporation Motorized implant delivery system
CN114072106B (zh) 2019-05-04 2025-09-19 维迪内股份有限公司 用于在自体瓣环中部署侧面递送的假体心脏瓣膜的束紧装置和方法
JP7621991B2 (ja) 2019-07-19 2025-01-27 エドワーズ ライフサイエンシーズ コーポレイション 人工心臓弁用のクリンピング装置
WO2021014457A1 (en) * 2019-07-22 2021-01-28 Meril Life Sciences Pvt Ltd Prosthetic heart valve
JP7597745B2 (ja) 2019-08-12 2024-12-10 エドワーズ ライフサイエンシーズ コーポレイション 人工心臓弁
CN121101808A (zh) 2019-08-20 2025-12-12 维迪内股份有限公司 用于可侧面递送经导管人工瓣膜的递送和取回装置和方法
EP4021445B8 (en) 2019-08-26 2025-12-10 VDyne, Inc. Side-deliverable transcatheter prosthetic valves
CN110507451B (zh) 2019-08-29 2025-11-18 上海翰凌医疗器械有限公司 瓣膜支架及具有其的人工瓣膜
AU2020396962A1 (en) 2019-12-06 2021-12-23 Edwards Lifesciences Corporation Flex sensors for measuring real-time valve diameter during procedure
WO2021141878A1 (en) 2020-01-10 2021-07-15 Edwards Lifesciences Corporation Assembly methods for a prosthetic heart valve leaflet
US11234813B2 (en) 2020-01-17 2022-02-01 Vdyne, Inc. Ventricular stability elements for side-deliverable prosthetic heart valves and methods of delivery
CN115426980A (zh) 2020-03-03 2022-12-02 爱德华兹生命科学公司 假体心脏瓣膜小叶连合部组合件和方法
US12011349B2 (en) * 2020-03-04 2024-06-18 Medtronic, Inc. Balloon expandable stent with lengthened commissure posts for transcatheter implantation of a cardiac valve prosthesis
EP4509098A3 (en) 2020-06-18 2025-05-28 Edwards Lifesciences Corporation Crimping methods
CN113907917B (zh) 2020-07-10 2025-10-28 爱德华兹生命科学公司 到假体瓣膜的框架的小叶和裙部附接构造
CN115835837A (zh) 2020-07-10 2023-03-21 爱德华兹生命科学公司 具有扩展和锁定组件的假体心脏瓣膜
EP4000559B1 (en) * 2020-11-13 2025-07-02 HVR Cardio Oy Annuloplasty device
EP4243734A1 (en) 2020-11-12 2023-09-20 Edwards Lifesciences Corporation Prosthetic heart valve leaflet assemblies and methods
CN114617674B (zh) * 2020-12-11 2024-12-06 上海微创心通医疗科技有限公司 一种人工心脏瓣膜假体
EP4247297A1 (en) 2020-12-18 2023-09-27 Edwards Lifesciences Corporation Storage jar assembly for aprosthetic heart valve
WO2022159427A1 (en) 2021-01-20 2022-07-28 Edwards Lifesciences Corporation Connecting skirt for attaching a leaflet to a frame of a prosthetic heart valve
CN219000724U (zh) 2021-03-23 2023-05-12 爱德华兹生命科学公司 假体心脏瓣膜
WO2022266004A1 (en) * 2021-06-14 2022-12-22 Edwards Lifesciences Corporation Expandable prosthetic heart valve frame with leaflet support struts
KR102918984B1 (ko) 2021-10-27 2026-01-28 에드워즈 라이프사이언시스 코포레이션 인공 심장 판막의 클림핑 및 로딩을 위한 시스템 및 방법
WO2023194877A2 (en) 2022-04-05 2023-10-12 Libra Science Ltd. Device and method for guiding trans-catheter aortic valve replacement procedure
USD1054562S1 (en) 2022-08-31 2024-12-17 Edwards Lifesciences Corporation Leaflet for a prosthetic heart valve
JP2025534210A (ja) 2022-10-14 2025-10-15 ブイダイン，インコーポレイテッド 弁輪上支持体を使用して人工心臓弁を送達するデバイス及び方法
EP4603061A1 (en) * 2024-02-19 2025-08-20 Tresquare Technologies S.r.l. Sutureless transcatheter heart valve prosthesis

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001047438A1 (en) * 1999-12-23 2001-07-05 Edwards Lifesciences Corporation Enhanced visualization of medical implants
US20020087186A1 (en) * 2001-01-04 2002-07-04 Scimed Life Systems, Inc. Expansion-assisting delivery system for self-expanding stent
US20030070676A1 (en) * 1999-08-05 2003-04-17 Cooper Joel D. Conduits having distal cage structure for maintaining collateral channels in tissue and related methods
US20060206202A1 (en) * 2004-11-19 2006-09-14 Philippe Bonhoeffer Apparatus for treatment of cardiac valves and method of its manufacture
US20070043435A1 (en) * 1999-11-17 2007-02-22 Jacques Seguin Non-cylindrical prosthetic valve system for transluminal delivery
US20090192591A1 (en) * 2008-01-24 2009-07-30 Medtronic, Inc. Markers for Prosthetic Heart Valves
US20090292262A1 (en) * 2007-10-12 2009-11-26 Martin Neal Adams Valve loader method, system, and apparatus
US20100100176A1 (en) 2003-10-06 2010-04-22 Ats Medical, Inc. Anchoring structure with concave landing zone
US20100168844A1 (en) 2007-01-26 2010-07-01 3F Therapeutics, Inc. Methods and systems for reducing paravalvular leakage in heart valves

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816029A (en) * 1981-05-07 1989-03-28 Medtronic, Inc. Stent for aortic heart valve
US6846325B2 (en) * 2000-09-07 2005-01-25 Viacor, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9532868B2 (en) * 2007-09-28 2017-01-03 St. Jude Medical, Inc. Collapsible-expandable prosthetic heart valves with structures for clamping native tissue

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030070676A1 (en) * 1999-08-05 2003-04-17 Cooper Joel D. Conduits having distal cage structure for maintaining collateral channels in tissue and related methods
US20070043435A1 (en) * 1999-11-17 2007-02-22 Jacques Seguin Non-cylindrical prosthetic valve system for transluminal delivery
WO2001047438A1 (en) * 1999-12-23 2001-07-05 Edwards Lifesciences Corporation Enhanced visualization of medical implants
US20020087186A1 (en) * 2001-01-04 2002-07-04 Scimed Life Systems, Inc. Expansion-assisting delivery system for self-expanding stent
US20100100176A1 (en) 2003-10-06 2010-04-22 Ats Medical, Inc. Anchoring structure with concave landing zone
US20060206202A1 (en) * 2004-11-19 2006-09-14 Philippe Bonhoeffer Apparatus for treatment of cardiac valves and method of its manufacture
US20100168844A1 (en) 2007-01-26 2010-07-01 3F Therapeutics, Inc. Methods and systems for reducing paravalvular leakage in heart valves
US20090292262A1 (en) * 2007-10-12 2009-11-26 Martin Neal Adams Valve loader method, system, and apparatus
US20090192591A1 (en) * 2008-01-24 2009-07-30 Medtronic, Inc. Markers for Prosthetic Heart Valves

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12239709B2 (en) 2011-12-07 2025-03-04 Alnylam Pharmaceuticals, Inc. Biodegradable lipids for the delivery of active agents
US12343398B2 (en) 2011-12-07 2025-07-01 Alnylam Pharmaceuticals, Inc. Biodegradable lipids for the delivery of active agents
US12350338B2 (en) 2011-12-07 2025-07-08 Alnylam Pharmaceuticals, Inc. Biodegradable lipids for the delivery of active agents
US12364762B2 (en) 2011-12-07 2025-07-22 Alnylam Pharmaceuticals, Inc. Biodegradable lipids for the delivery of active agents

Also Published As

Publication number Publication date
EP2991585A1 (en) 2016-03-09
EP2991585B1 (en) 2023-08-16
US20140330372A1 (en) 2014-11-06
JP2016517748A (ja) 2016-06-20

Similar Documents

Publication Publication Date Title
EP2991585B1 (en) Medical devices for implanting in a valve
EP3760164B2 (en) Heart valve with anchoring structure having concave landing zone
EP2991584B1 (en) Prosthetic valves
EP3541327B1 (en) Prosthetic heart valve having leaflet inflow below frame
US9675452B2 (en) Artificial heart valve with scalloped frame design
US8876897B2 (en) Implantable prosthetic valves and methods relating to same
US9700409B2 (en) Reduced profile prosthetic heart valve
CA2812536C (en) Prosthetic heart valve frame with flexible commissures
CA2793916C (en) Prosthetic heart valve
US20100168844A1 (en) Methods and systems for reducing paravalvular leakage in heart valves
EP3753535A1 (en) Transcatheter valve prosthesis having an external skirt for sealing and preventing paravalvular leakage

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14729789

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2016512085

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2014729789

Country of ref document: EP