WO2014165713A3 - Traitement des affections inflammatoires par modulation de l'activité hyaluronane et hyaluronidase - Google Patents
Traitement des affections inflammatoires par modulation de l'activité hyaluronane et hyaluronidase Download PDFInfo
- Publication number
- WO2014165713A3 WO2014165713A3 PCT/US2014/032893 US2014032893W WO2014165713A3 WO 2014165713 A3 WO2014165713 A3 WO 2014165713A3 US 2014032893 W US2014032893 W US 2014032893W WO 2014165713 A3 WO2014165713 A3 WO 2014165713A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hyaluronan
- inflammatory conditions
- modulation
- treatment
- hyaluronidase activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2474—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Dermatology (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14780170.8A EP2981283A4 (fr) | 2013-04-03 | 2014-04-03 | Traitement des affections inflammatoires par modulation de l'activité hyaluronane et hyaluronidase |
US14/782,269 US9763969B2 (en) | 2013-04-03 | 2014-04-03 | Treatment of inflammatory conditions with hyaluronan disaccharide |
CA2907586A CA2907586A1 (fr) | 2013-04-03 | 2014-04-03 | Traitement des affections inflammatoires par modulation de l'activite hyaluronane et hyaluronidase |
CN201480020033.0A CN105120889B (zh) | 2013-04-03 | 2014-04-03 | 通过调节乙酰透明质酸和透明质酸酶活性而治疗炎性病状 |
KR1020157027060A KR20150138219A (ko) | 2013-04-03 | 2014-04-03 | 히알루로난 및 히알루로니다제 활성의 조절에 의한 염증성 병태의 치료 |
US15/684,208 US20170348338A1 (en) | 2013-04-03 | 2017-08-23 | Treatment of inflammatory conditions by modulation of hyaluronan and hyaluronidase activity |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361808063P | 2013-04-03 | 2013-04-03 | |
US61/808,063 | 2013-04-03 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/782,269 A-371-Of-International US9763969B2 (en) | 2013-04-03 | 2014-04-03 | Treatment of inflammatory conditions with hyaluronan disaccharide |
US15/684,208 Division US20170348338A1 (en) | 2013-04-03 | 2017-08-23 | Treatment of inflammatory conditions by modulation of hyaluronan and hyaluronidase activity |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2014165713A2 WO2014165713A2 (fr) | 2014-10-09 |
WO2014165713A3 true WO2014165713A3 (fr) | 2015-06-18 |
Family
ID=51659352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2014/032893 WO2014165713A2 (fr) | 2013-04-03 | 2014-04-03 | Traitement des affections inflammatoires par modulation de l'activité hyaluronane et hyaluronidase |
Country Status (6)
Country | Link |
---|---|
US (2) | US9763969B2 (fr) |
EP (1) | EP2981283A4 (fr) |
KR (1) | KR20150138219A (fr) |
CN (1) | CN105120889B (fr) |
CA (1) | CA2907586A1 (fr) |
WO (1) | WO2014165713A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9763969B2 (en) | 2013-04-03 | 2017-09-19 | Cedars-Sinai Medical Center | Treatment of inflammatory conditions with hyaluronan disaccharide |
US20190022207A1 (en) * | 2015-07-30 | 2019-01-24 | Cedars-Sinai Medical Center | Compositions and Methods for Treating Acne |
AU2017255833B2 (en) | 2016-04-25 | 2022-09-01 | Mizhou Hui | Application of small-molecule hyaluronic acid fragment |
US11306157B2 (en) | 2018-12-21 | 2022-04-19 | California Institute Of Technology | Expedient synthesis of core disaccharide building blocks from natural polysaccharides for heparan sulfate oligosaccharide assembly |
WO2021213623A1 (fr) * | 2020-04-20 | 2021-10-28 | Pharmact Holding Ag | Polypeptide hyaluronidase bactérien modifié, procédé de production, compositions pharmaceutiques et leurs utilisations |
WO2023067008A1 (fr) * | 2021-10-19 | 2023-04-27 | Pharmact Holding Ag | Production d'un polypeptide hyaluronidase bactérien modifié purifié, compositions pharmaceutiques et leurs utilisations |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020086852A1 (en) * | 1998-05-14 | 2002-07-04 | Cantor Jerome O. | Method for treating respiratory disorders associated with pulmonary elastic fiber injury |
US20070099867A1 (en) * | 2005-05-24 | 2007-05-03 | Glycoscience Laboratories, Inc. | Pharmaceutical agent containing hyaluronan as an active ingredient |
WO2011156445A1 (fr) * | 2010-06-08 | 2011-12-15 | University Of Utah Research Foundation | Applications de hyaluronane partiellement ou entièrement sulfaté |
US20130059769A1 (en) * | 2010-05-10 | 2013-03-07 | Eva Turley | Topically administered, skin-penetrating glycosaminoglycan formulations suitable for use in cosmetic and pharmaceutical applications |
US20130072452A1 (en) * | 2011-09-16 | 2013-03-21 | China Medical University | Pharmaceutical composition and method for inhibiting inflammation |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1340994C (fr) | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Traitement de maladies et d'etats pathologiques |
US20030162760A1 (en) | 1999-01-26 | 2003-08-28 | Eiko Masatsuji | Dermal agent |
ITMI20021866A1 (it) | 2002-08-30 | 2004-02-29 | Luigi Allegra | Preparazione farmaceutica in forma colloidale utile nella cura delle affezioni cutanee. |
EP2330213A1 (fr) | 2003-03-05 | 2011-06-08 | Halozyme, Inc. | Glycoprotéine d'hyaluronidase soluble (sHASEGP), son procédé de préparation, utilisations et compositions pharmaceutiques le comportant |
JP2007084509A (ja) * | 2005-09-26 | 2007-04-05 | Toshitsu Kagaku Kenkyusho:Kk | 細胞賦活剤 |
JP5457675B2 (ja) * | 2006-10-17 | 2014-04-02 | 株式会社ヒアルロン酸研究所 | アトピー性皮膚炎の治療薬又は予防薬 |
CA2686931A1 (fr) * | 2007-05-11 | 2008-11-20 | Galderma Research & Development | Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations |
US20100323983A1 (en) * | 2007-05-11 | 2010-12-23 | Marc Moutet | Pharmaceutical or cosmetic preparations for topical and/or parenteral application, preparation methods thereof, and uses thereof |
US8288142B2 (en) | 2007-06-19 | 2012-10-16 | Uvarkina Tamara P | Hyaluronidase and method of use thereof |
JP4754532B2 (ja) * | 2007-07-09 | 2011-08-24 | 生化学工業株式会社 | ヒアルロン酸オリゴ糖を有効成分とする治療剤 |
US9763969B2 (en) | 2013-04-03 | 2017-09-19 | Cedars-Sinai Medical Center | Treatment of inflammatory conditions with hyaluronan disaccharide |
-
2014
- 2014-04-03 US US14/782,269 patent/US9763969B2/en active Active
- 2014-04-03 CN CN201480020033.0A patent/CN105120889B/zh not_active Expired - Fee Related
- 2014-04-03 EP EP14780170.8A patent/EP2981283A4/fr not_active Withdrawn
- 2014-04-03 CA CA2907586A patent/CA2907586A1/fr not_active Abandoned
- 2014-04-03 KR KR1020157027060A patent/KR20150138219A/ko not_active Application Discontinuation
- 2014-04-03 WO PCT/US2014/032893 patent/WO2014165713A2/fr active Application Filing
-
2017
- 2017-08-23 US US15/684,208 patent/US20170348338A1/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020086852A1 (en) * | 1998-05-14 | 2002-07-04 | Cantor Jerome O. | Method for treating respiratory disorders associated with pulmonary elastic fiber injury |
US20070099867A1 (en) * | 2005-05-24 | 2007-05-03 | Glycoscience Laboratories, Inc. | Pharmaceutical agent containing hyaluronan as an active ingredient |
US20130059769A1 (en) * | 2010-05-10 | 2013-03-07 | Eva Turley | Topically administered, skin-penetrating glycosaminoglycan formulations suitable for use in cosmetic and pharmaceutical applications |
WO2011156445A1 (fr) * | 2010-06-08 | 2011-12-15 | University Of Utah Research Foundation | Applications de hyaluronane partiellement ou entièrement sulfaté |
US20130072452A1 (en) * | 2011-09-16 | 2013-03-21 | China Medical University | Pharmaceutical composition and method for inhibiting inflammation |
Non-Patent Citations (1)
Title |
---|
See also references of EP2981283A4 * |
Also Published As
Publication number | Publication date |
---|---|
WO2014165713A2 (fr) | 2014-10-09 |
US9763969B2 (en) | 2017-09-19 |
US20170348338A1 (en) | 2017-12-07 |
EP2981283A2 (fr) | 2016-02-10 |
CA2907586A1 (fr) | 2014-10-09 |
EP2981283A4 (fr) | 2017-07-05 |
CN105120889B (zh) | 2018-04-13 |
KR20150138219A (ko) | 2015-12-09 |
US20160022715A1 (en) | 2016-01-28 |
CN105120889A (zh) | 2015-12-02 |
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