WO2014155389A3 - Procédé de préparation de ticagrelor - Google Patents
Procédé de préparation de ticagrelor Download PDFInfo
- Publication number
- WO2014155389A3 WO2014155389A3 PCT/IN2014/000165 IN2014000165W WO2014155389A3 WO 2014155389 A3 WO2014155389 A3 WO 2014155389A3 IN 2014000165 W IN2014000165 W IN 2014000165W WO 2014155389 A3 WO2014155389 A3 WO 2014155389A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ticagrelor
- preparation
- pharmaceutically acceptable
- relates
- acceptable salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La présente invention concerne un procédé de préparation de ticagrelor et de ses sels pharmaceutiquement acceptables.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1111/MUM/2013 | 2013-03-25 | ||
IN1111MU2013 IN2013MU01111A (fr) | 2013-03-25 | 2014-03-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2014155389A2 WO2014155389A2 (fr) | 2014-10-02 |
WO2014155389A3 true WO2014155389A3 (fr) | 2015-01-15 |
Family
ID=51625566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2014/000165 WO2014155389A2 (fr) | 2013-03-25 | 2014-03-14 | Procédé de préparation de ticagrelor |
Country Status (2)
Country | Link |
---|---|
IN (1) | IN2013MU01111A (fr) |
WO (1) | WO2014155389A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105801583A (zh) * | 2014-12-31 | 2016-07-27 | 徐州万邦金桥制药有限公司 | 一种替格瑞洛的纯化方法 |
CN109633063B (zh) * | 2018-12-26 | 2021-05-04 | 哈尔滨医科大学 | 一种人血浆中替格瑞洛及其活性代谢产物浓度的检测方法 |
CN112394109A (zh) * | 2019-08-12 | 2021-02-23 | 武汉武药科技有限公司 | 替格瑞洛中杂质的检测方法 |
CN110642862B (zh) * | 2019-10-29 | 2021-01-26 | 株洲千金药业股份有限公司 | 一种替格瑞洛乙酯化杂质的制备方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000034283A1 (fr) * | 1998-12-04 | 2000-06-15 | Astrazeneca Ab | Nouveaux composes de triazolo(4,5-d)pyrimidine |
CN1432018A (zh) * | 2000-06-02 | 2003-07-23 | 阿斯特拉曾尼卡有限公司 | 三唑并[4,5-d]嘧啶化合物的新晶形和非晶形 |
CN102603751A (zh) * | 2012-02-24 | 2012-07-25 | 中国药科大学 | 三唑并(4,5-d)嘧啶衍生物及其制备方法与在制药中的用途 |
WO2012138981A2 (fr) * | 2011-04-06 | 2012-10-11 | Teva Pharmaceutical Industries Ltd. | Nouveaux intermédiaires et procédés pour la préparation du ticagrelor |
CN102731467A (zh) * | 2011-04-15 | 2012-10-17 | 博瑞生物医药技术(苏州)有限公司 | 替卡格雷的中间体及制备替卡格雷的方法 |
CN102875537A (zh) * | 2012-09-10 | 2013-01-16 | 常州制药厂有限公司 | 一种新的抗血栓药物的制备方法 |
-
2014
- 2014-03-14 WO PCT/IN2014/000165 patent/WO2014155389A2/fr active Application Filing
- 2014-03-14 IN IN1111MU2013 patent/IN2013MU01111A/en unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000034283A1 (fr) * | 1998-12-04 | 2000-06-15 | Astrazeneca Ab | Nouveaux composes de triazolo(4,5-d)pyrimidine |
CN1432018A (zh) * | 2000-06-02 | 2003-07-23 | 阿斯特拉曾尼卡有限公司 | 三唑并[4,5-d]嘧啶化合物的新晶形和非晶形 |
WO2012138981A2 (fr) * | 2011-04-06 | 2012-10-11 | Teva Pharmaceutical Industries Ltd. | Nouveaux intermédiaires et procédés pour la préparation du ticagrelor |
CN102731467A (zh) * | 2011-04-15 | 2012-10-17 | 博瑞生物医药技术(苏州)有限公司 | 替卡格雷的中间体及制备替卡格雷的方法 |
CN102603751A (zh) * | 2012-02-24 | 2012-07-25 | 中国药科大学 | 三唑并(4,5-d)嘧啶衍生物及其制备方法与在制药中的用途 |
CN102875537A (zh) * | 2012-09-10 | 2013-01-16 | 常州制药厂有限公司 | 一种新的抗血栓药物的制备方法 |
Also Published As
Publication number | Publication date |
---|---|
WO2014155389A2 (fr) | 2014-10-02 |
IN2013MU01111A (fr) | 2015-05-01 |
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