WO2014131178A1 - Appareil de poursuite respiratoire et système de radiothérapie - Google Patents

Appareil de poursuite respiratoire et système de radiothérapie Download PDF

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Publication number
WO2014131178A1
WO2014131178A1 PCT/CN2013/071997 CN2013071997W WO2014131178A1 WO 2014131178 A1 WO2014131178 A1 WO 2014131178A1 CN 2013071997 W CN2013071997 W CN 2013071997W WO 2014131178 A1 WO2014131178 A1 WO 2014131178A1
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WO
WIPO (PCT)
Prior art keywords
respiratory
patient
module
frequency
control module
Prior art date
Application number
PCT/CN2013/071997
Other languages
English (en)
Chinese (zh)
Inventor
吴中华
Original Assignee
深圳市奥沃医学新技术发展有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳市奥沃医学新技术发展有限公司 filed Critical 深圳市奥沃医学新技术发展有限公司
Priority to PCT/CN2013/071997 priority Critical patent/WO2014131178A1/fr
Priority to CN201380004410.7A priority patent/CN104220132B/zh
Publication of WO2014131178A1 publication Critical patent/WO2014131178A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/113Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computed tomography [CT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1064Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1069Target adjustment, e.g. moving the patient support
    • A61N5/107Target adjustment, e.g. moving the patient support in real time, i.e. during treatment

Definitions

  • the invention belongs to the field of precise radiation therapy in the medical field, and in particular relates to a respiratory tracking device and a radiation therapy system. Background technique
  • Accurate radiotherapy is a three-dimensional treatment technology based on high-resolution image detection devices for precise positioning, positioning, and illumination.
  • Accurate radiotherapy can reduce the probability of normal tissue surrounding the target area, increase the dose of tumor area, and increase the rate of tumor control.
  • human tumors, especially chest and abdomen tumors move with the breathing movement of the human body, and the irradiation field is relatively static, which causes the exposure dose of important normal tissues in the target area and its surroundings to be significantly different from that of the plan.
  • the accuracy of the treatment is affected. Therefore, in the precise radiotherapy of tumors, especially chest and abdomen tumors, it is necessary to use respiratory tracking devices to reduce the adverse effects of respiratory movements.
  • the existing respiratory tracking device generally adopts a human body external fixed marker body, and the movement law of the marker body is collected by a high speed camera to judge the respiratory state of the lungs; or it is judged by installing a bundled expansion and contraction on the human chest to collect the chest ups and downs of the human body. Breathing of the lungs.
  • the patient In the case of respiratory collection, the patient is required to collect respiratory conditions at the end of inspiration or at the end of expiration to make a treatment plan.
  • the treatment device starts treatment only when the patient is relatively stable at the end of expiration or inhalation.
  • the device stops treatment when the patient starts inhaling or exhaling again, thereby achieving respiratory tracking.
  • a respiratory tracking device is intermittent, does not have the characteristics of real-time tracking, and cannot accurately track a tumor that is moved due to the position of the breath.
  • a breathing tracking device includes a breathing control module, an analysis comparison module, and a treatment control module, wherein: the breathing control module is coupled to the analysis comparison module for controlling the output of the breathing Flow rate and respiratory rate, and transmitting a time trajectory coordinate value of the tumor position movement and a patient respiratory waveform and frequency to the analysis comparison module; the analysis comparison module is coupled to the respiratory control module and the treatment control module Receiving a time trajectory coordinate value of the tumor position movement and the patient respiratory waveform and frequency sent by the respiratory control module, and comparing the patient respiratory waveform and frequency with a respiratory waveform and frequency collected during planned design, When the difference between the respiratory waveform and the frequency of the patient and the respiratory waveform and frequency collected during the planned design is less than or equal to a preset value, the treatment control module is instructed to control the treatment according to the time trajectory coordinate value of the movement of the tumor position The device is treated; and the treatment control module is coupled to the Analysis of comparison module, for treatment according to the analysis and comparison of the indication of the module, the position of
  • the analysis comparison module instructs the treatment control module to stop the treatment.
  • the breathing control module further comprises a breathing supply recording module, an image scanning module and a tumor position calculating module, wherein: the breathing supply and recording module is connected to the tumor position calculating module, according to a preset respiratory flow Supplying oxygen to the patient at a respiratory rate, recording a respiratory waveform and frequency of the patient, and transmitting the patient respiratory waveform and frequency to the tumor location calculation module; and the image scanning module being coupled to the tumor location calculation The module performs image scanning on the patient while the patient is breathing smoothly, and sends the scanned patient dynamic image to the tumor location calculation module.
  • the tumor position calculation module is connected to the respiratory supply recording module and the image scanning module, and receives the patient respiratory waveform and frequency sent by the respiratory supply and recording module and the image scanning module sends The patient dynamic image, based on the patient dynamic image and Calculating a time trajectory coordinate value of the movement of the tumor position in the respiratory waveform and frequency of the patient, and calculating a time trajectory coordinate value of the movement of the tumor position and a respiratory waveform of the patient and The frequency is sent to the analysis comparison module.
  • the image scan of the patient is scanned for at least one complete respiratory frequency period.
  • the image scanning module is a dynamic CT.
  • Another object of the present invention is to provide a radiation therapy system comprising the respiratory tracking device described above.
  • the treatment device treats the patient based on the indication of the treatment control module in the respiratory tracking device.
  • the respiratory tracking device and the radiation therapy system provided by the present invention can accurately track and treat tumors that move due to the position of the breathing.
  • BRIEF DESCRIPTION OF THE DRAWINGS In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the prior art description will be briefly described below, and obviously, in the following description The drawings are only some of the embodiments of the present invention, and those skilled in the art can obtain other drawings based on these drawings without any creative work.
  • FIG. 1 is a block diagram showing the structure of a respiratory tracking apparatus according to an embodiment of the present invention.
  • FIG. 2 is a structural block diagram of a radiation therapy system according to an embodiment of the present invention. detailed description
  • FIG. 1 is a structural block diagram of a respiratory tracking apparatus according to an embodiment of the present invention.
  • the respiratory tracking device 100 includes a respiratory control module 110, an analytical comparison module 120, and a treatment control module 130.
  • the breathing control module 110 is coupled to the analysis comparison module 120 for controlling the respiratory flow and respiratory frequency of the output thereof, and transmitting the time trajectory coordinate value of the patient tumor position movement and the patient respiratory waveform and frequency to the analysis comparison module 120.
  • the breathing control module 110 further includes: a breathing supply recording module 111, an image scanning module 113, and a tumor position calculating module 115.
  • the breathing supply and recording module 111 is connected to the tumor position calculating module 115, supplies oxygen to the patient according to the preset respiratory flow rate and respiratory frequency, records the respiratory waveform and frequency of the patient, and transmits the recorded respiratory waveform and frequency of the patient to the tumor.
  • Location calculation module 115 is connected to the tumor position calculating module 115, supplies oxygen to the patient according to the preset respiratory flow rate and respiratory frequency, records the respiratory waveform and frequency of the patient, and transmits the recorded respiratory waveform and frequency of the patient to the tumor.
  • the image scanning module 113 is connected to the tumor position calculating module 115, and performs image scanning on the patient while the patient is breathing smoothly, and sends the scanned patient dynamic image to the tumor position calculating module 115, wherein the image scanning range is at least A complete respiratory frequency cycle, a complete respiratory frequency cycle refers to a complete exhalation plus inhalation process, and the image scanning module 113 can be a dynamic CT.
  • the tumor position calculation module 115 is connected to the respiratory supply recording module 111 and the image scanning module 113, and receives the patient respiratory waveform and frequency sent by the respiratory supply and recording module 111 and the patient dynamic image transmitted by the image scanning module 113, according to the patient dynamic image and the patient.
  • the respiratory waveform and frequency are used to calculate the time trajectory coordinate value of the tumor position movement of the patient in the respiratory waveform and frequency, and the time trajectory coordinate value and the patient respiratory waveform and frequency are sent to the analysis comparison module 120.
  • the analysis comparison module 120 is connected to the tumor position calculation module 115 and the treatment control module 130, and receives the time trajectory coordinate value of the tumor position movement and the patient respiratory waveform and frequency sent by the tumor position calculation module 115, and the patient respiratory waveform and frequency and the plan The respiratory waveform and the frequency collected during the design are compared. When the difference between the respiratory waveform and the frequency of the patient and the respiratory waveform and frequency collected during the planned design is less than or equal to the preset value, the analysis comparison module 120 instructs the treatment control module 130 to follow the The time trajectory coordinate value of the tumor position movement controls the treatment device for treatment.
  • the analysis comparison module 120 instructs the treatment control module 130 to stop the treatment, and after the patient's breathing condition is adjusted to stabilize the breathing, Continue treatment.
  • the treatment control module 130 is coupled to the analysis comparison module 120 and controls the treatment device to perform treatment according to the time trajectory coordinate value of the tumor position movement according to the indication of the analysis comparison module 120.
  • the analysis comparison module 120 continuously compares the collected patient respiratory waveform and frequency with the respiratory waveform and frequency collected during the planned design, if the preset value is exceeded (ie, The error allowed value will terminate the treatment.
  • the radiation therapy system includes a respiratory tracking device 100 and a treatment device 200 that treats the patient based on instructions from the therapy control module 130 in the respiratory tracking device 100.
  • the respiratory tracking device and the radiation therapy system provided by the present invention are capable of accurately tracking and treating tumors that move due to the position of the breathing.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

La présente invention concerne un appareil de poursuite respiratoire (100) et un système de radiothérapie, associés au domaine de la radiothérapie. L'appareil de poursuite respiratoire (100) comprend : un module de contrôle de respiration (110) qui est connecté à un module d'analyse et de comparaison (120) et est utilisé pour contrôler un débit respiratoire de sortie et une fréquence respiratoire, et pour transmettre des valeurs de coordonnées de temps-trajectoire d'un mouvement de position d'une tumeur et une forme d'onde et une fréquence respiratoires d'un patient au module d'analyse et de comparaison (120) ; le module d'analyse et de comparaison (120) qui est connecté à un module de commande de traitement (130) compare la forme d'onde et la fréquence respiratoires du patient à la forme d'onde et la fréquence respiratoires collectées pendant la planification et la conception, et, lorsque la différence est inférieure ou égale à une valeur prédéterminée, donne une instruction au module de commande de traitement (130) pour commander, sur la base des valeurs de coordonnées temps-trajectoire du mouvement de position de la tumeur, un appareil de traitement (200) pour conduire un traitement ; et, le module de commande de traitement (130) qui commande, sur la base de l'instruction du module d'analyse et de comparaison (120), l'appareil de traitement (200) de manière à conduire le traitement. L'appareil de poursuite respiratoire (100) et le système de radiothérapie sont en mesure de suivre et traiter précisément une tumeur qui change de position en raison de la respiration.
PCT/CN2013/071997 2013-02-28 2013-02-28 Appareil de poursuite respiratoire et système de radiothérapie WO2014131178A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/CN2013/071997 WO2014131178A1 (fr) 2013-02-28 2013-02-28 Appareil de poursuite respiratoire et système de radiothérapie
CN201380004410.7A CN104220132B (zh) 2013-02-28 2013-02-28 一种呼吸跟踪装置及放射治疗系统

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Application Number Priority Date Filing Date Title
PCT/CN2013/071997 WO2014131178A1 (fr) 2013-02-28 2013-02-28 Appareil de poursuite respiratoire et système de radiothérapie

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Cited By (1)

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CN110613427A (zh) * 2014-12-02 2019-12-27 博医来股份公司 从热图像确定呼吸信号

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CN107126192B (zh) * 2017-04-18 2020-03-06 四川省肿瘤医院 一种肿瘤位置实时监测系统及其监测方法
CN110366389B (zh) * 2017-06-19 2023-03-03 深圳市奥沃医学新技术发展有限公司 利用放疗设备确定目标靶点位置的系统、装置和放疗设备
US11241589B2 (en) 2017-06-19 2022-02-08 Our New Medical Technologies Target tracking and irradiation method and device using radiotherapy apparatus and radiotherapy apparatus
CN109363702B (zh) * 2018-09-29 2023-01-20 上海联影医疗科技股份有限公司 医学成像方法、系统及辐射剂量的获取方法、系统
WO2020124583A1 (fr) * 2018-12-21 2020-06-25 四川省肿瘤医院 Système de surveillance de la position de tumeursen temps réel et procédé de surveillance associé
CN109965884A (zh) * 2019-04-19 2019-07-05 哈尔滨理工大学 一种基于加速度传感器的体表呼吸运动测量系统
CN110237446B (zh) * 2019-07-09 2024-05-03 冯丽娟 一种用于肿瘤放射治疗的呼吸门控设备
CN114052767B (zh) * 2022-01-14 2022-03-22 常州复睿特生物科技有限公司 一种肺癌分子标记物检测装置

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CN110613427B (zh) * 2014-12-02 2022-06-21 博医来股份公司 从热图像确定呼吸信号

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Publication number Publication date
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CN104220132B (zh) 2017-05-24

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