WO2014097272A3 - Process for the preparation of (s,s)-6-benzloctahydro-1 h-pyrrolo[3,4-b]pyridine,an intermediate of azabicyclopyridine derivatives - Google Patents

Process for the preparation of (s,s)-6-benzloctahydro-1 h-pyrrolo[3,4-b]pyridine,an intermediate of azabicyclopyridine derivatives Download PDF

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Publication number
WO2014097272A3
WO2014097272A3 PCT/IB2013/061274 IB2013061274W WO2014097272A3 WO 2014097272 A3 WO2014097272 A3 WO 2014097272A3 IB 2013061274 W IB2013061274 W IB 2013061274W WO 2014097272 A3 WO2014097272 A3 WO 2014097272A3
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WO
WIPO (PCT)
Prior art keywords
pyridine
pyrrolo
derivatives
benzloctahydro
azabicyclopyridine
Prior art date
Application number
PCT/IB2013/061274
Other languages
French (fr)
Other versions
WO2014097272A2 (en
Inventor
Jigar BHAVSAR
Akhilendra SINGH
Bhuwan Bhaskar
Anil Kumar
Original Assignee
Mankind Research Centre
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Publication date
Application filed by Mankind Research Centre filed Critical Mankind Research Centre
Priority to CN201380066472.0A priority Critical patent/CN105143219A/en
Publication of WO2014097272A2 publication Critical patent/WO2014097272A2/en
Publication of WO2014097272A3 publication Critical patent/WO2014097272A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

The present invention relates to a cost effective process for the production of (S,S)-6- benzyloctahydro-1H-pyrrolo[3,4-b]pyridine of Formula (I), an important intermediate for the manufacture of azabicyclo pyridine derivatives.
PCT/IB2013/061274 2012-12-21 2013-12-23 Method for production of (s,s)-6-benzyloctahydro-1h-pyrrolo[3,4-b]pyridine, an intermediate of azabicyclo pyridine derivatives WO2014097272A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201380066472.0A CN105143219A (en) 2012-12-21 2013-12-23 Process for the preparation of (S,S)-6-benzloctahydro-1 h-pyrrolo[3,4-b]pyridine,an intermediate of azabicyclopyridine derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN3980DE2012 2012-12-21
IN3980/DEL/2012 2012-12-21
IN684/DEL/2013 2013-03-09
IN684DE2013 2013-03-09

Publications (2)

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WO2014097272A2 WO2014097272A2 (en) 2014-06-26
WO2014097272A3 true WO2014097272A3 (en) 2015-07-16

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PCT/IB2013/061274 WO2014097272A2 (en) 2012-12-21 2013-12-23 Method for production of (s,s)-6-benzyloctahydro-1h-pyrrolo[3,4-b]pyridine, an intermediate of azabicyclo pyridine derivatives

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CN (1) CN105143219A (en)
WO (1) WO2014097272A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105153155B (en) * 2015-09-18 2017-01-18 华东师范大学 Preparation method for 6-benzyl-5,7-dioxo-1,2,3,4-tetrahydro-pyrrolo-[3,4-b] pyridine
CN105777750A (en) * 2016-04-13 2016-07-20 江西中德诚信科技有限公司 Synthesis method for moxifloxacin side chain
CN108623583B (en) * 2018-05-04 2021-01-15 新乡学院 Preparation method of iridium-catalyzed moxifloxacin side chain intermediate
CN114907347A (en) * 2022-07-12 2022-08-16 山东国邦药业有限公司 Preparation method of (4aS,7aS) -6-benzyl octahydro-1H-pyrrolo [3,4-b ] pyridine

Citations (1)

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CN101591336A (en) * 2009-06-25 2009-12-02 浙江燎原药业有限公司 8-benzyl-2, the method for reducing of 8-diazabicyclo [4,3,0] nonane and chiral isomer thereof

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DE3906365A1 (en) 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
CA1340553C (en) 1989-07-13 1999-05-18 Uwe Petersen Diazabicyclo compounds
DE19927412A1 (en) * 1999-06-16 2000-12-21 Bayer Ag Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane
JP2001039979A (en) 1999-07-28 2001-02-13 Koei Chem Co Ltd PRODUCTION OF OCTAHYDROPYRROLO[3,4-b]PYRIDINE
JP2004500090A (en) 2000-02-17 2004-01-08 ウェルチ・フーズ・インク Calcium-enriched grape-based products and methods for their production
DE10226923A1 (en) * 2002-06-17 2003-12-24 Bayer Ag Process for the enantiomer enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane
CN101429199B (en) 2008-09-08 2010-12-15 华东师范大学 Process for producing racemic cis-8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonyl hydride
CN101857199B (en) 2010-05-20 2012-02-08 复旦大学 Method for preparing Al(BH4)3-6NH3 hydrogen storage material
JP2012067033A (en) 2010-09-22 2012-04-05 Kuraray Co Ltd Method for producing aminomethylpyridine derivative
WO2012131629A1 (en) 2011-03-31 2012-10-04 Piramal Healthcare Limited A process for preparation of intermediate of moxifloxacin

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101591336A (en) * 2009-06-25 2009-12-02 浙江燎原药业有限公司 8-benzyl-2, the method for reducing of 8-diazabicyclo [4,3,0] nonane and chiral isomer thereof

Non-Patent Citations (1)

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Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; TU, XIONGFEI: "Reduction method of 8-benzyl-2,8-diazabicyclo[4,3,0]nonane and its chiral isomer", XP002725476, retrieved from STN Database accession no. 2009:1525999 *

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WO2014097272A2 (en) 2014-06-26
CN105143219A (en) 2015-12-09

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