WO2014091386A3 - An improved process for preparation of minodronic acid - Google Patents

An improved process for preparation of minodronic acid Download PDF

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Publication number
WO2014091386A3
WO2014091386A3 PCT/IB2013/060737 IB2013060737W WO2014091386A3 WO 2014091386 A3 WO2014091386 A3 WO 2014091386A3 IB 2013060737 W IB2013060737 W IB 2013060737W WO 2014091386 A3 WO2014091386 A3 WO 2014091386A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
minodronic acid
improved process
present
minodronic
Prior art date
Application number
PCT/IB2013/060737
Other languages
French (fr)
Other versions
WO2014091386A2 (en
Inventor
Venkat Raman JAYARAMAN
Bijukumar Gopinathan Pillai
Venkata Ramana Kondepati
Dhamesh DHAMELIYA
Veerabhadrarao BOBBILI
Original Assignee
Alembic Pharmaceuticals Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alembic Pharmaceuticals Limited filed Critical Alembic Pharmaceuticals Limited
Publication of WO2014091386A2 publication Critical patent/WO2014091386A2/en
Publication of WO2014091386A3 publication Critical patent/WO2014091386A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to an improved process for the preparation of Minodronic acid. The present invention particularly relates to a process for the preparation of Minodronic acid from imidazo [1,2-a]pyridine.
PCT/IB2013/060737 2012-12-13 2013-12-09 An improved process for preparation of minodronic acid WO2014091386A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN3517/MUM/2012 2012-12-13
IN3517MU2012 IN2012MU03517A (en) 2012-12-13 2013-12-09

Publications (2)

Publication Number Publication Date
WO2014091386A2 WO2014091386A2 (en) 2014-06-19
WO2014091386A3 true WO2014091386A3 (en) 2014-08-07

Family

ID=50935044

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/060737 WO2014091386A2 (en) 2012-12-13 2013-12-09 An improved process for preparation of minodronic acid

Country Status (2)

Country Link
IN (1) IN2012MU03517A (en)
WO (1) WO2014091386A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107033187A (en) * 2017-04-28 2017-08-11 江苏笃诚医药科技股份有限公司 A kind of preparation method of minodronic acid

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016024287A1 (en) * 2014-08-14 2016-02-18 Ind-Swift Laboratories Limited An improved process for preparing pure minodronic acid and intermediates thereof
CN104497048A (en) * 2014-12-10 2015-04-08 哈药集团技术中心 Preparation method of minodronic acid
CN108690019A (en) * 2018-07-04 2018-10-23 南京拉艾夫医药科技有限公司 Minodronate intermediate synthesis system and its synthesis technology
CN114384186A (en) * 2022-01-21 2022-04-22 王立强 Method for measuring content of (2E, 4E) -ethyl-4- (pyridine-2-yl imino) -2-ethyl crotonate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002014306A1 (en) * 2000-08-17 2002-02-21 Cilag Ag Process for the preparation of imidazopyridines
WO2007023504A1 (en) * 2005-08-24 2007-03-01 Elder Pharmaceuticals Ltd Process for the preparation of imidazopyridines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002014306A1 (en) * 2000-08-17 2002-02-21 Cilag Ag Process for the preparation of imidazopyridines
WO2007023504A1 (en) * 2005-08-24 2007-03-01 Elder Pharmaceuticals Ltd Process for the preparation of imidazopyridines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DIVVELA V. N. SRINIVASA RAO ET AL.: "facile one pot synthesis of bisphosphonic acids and their sodium salts from nitriles", ARKIVOC, vol. XIV, 2007, pages 34 - 38 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107033187A (en) * 2017-04-28 2017-08-11 江苏笃诚医药科技股份有限公司 A kind of preparation method of minodronic acid

Also Published As

Publication number Publication date
IN2012MU03517A (en) 2015-06-26
WO2014091386A2 (en) 2014-06-19

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