WO2014054459A1 - 美容機器、通電方法及び記録媒体 - Google Patents

美容機器、通電方法及び記録媒体 Download PDF

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Publication number
WO2014054459A1
WO2014054459A1 PCT/JP2013/075730 JP2013075730W WO2014054459A1 WO 2014054459 A1 WO2014054459 A1 WO 2014054459A1 JP 2013075730 W JP2013075730 W JP 2013075730W WO 2014054459 A1 WO2014054459 A1 WO 2014054459A1
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WO
WIPO (PCT)
Prior art keywords
signal
ion introduction
alternating current
high frequency
information processing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2013/075730
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English (en)
French (fr)
Japanese (ja)
Inventor
直輝 齋藤
雄一郎 森
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Shiseido Co Ltd
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Shiseido Co Ltd
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Filing date
Publication date
Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Priority to EP13843096.2A priority Critical patent/EP2905048A4/en
Priority to CN201380051019.2A priority patent/CN104684612B/zh
Priority to US14/430,977 priority patent/US9981125B2/en
Priority to KR1020157008243A priority patent/KR101571450B1/ko
Priority to HK15105640.6A priority patent/HK1205027B/xx
Publication of WO2014054459A1 publication Critical patent/WO2014054459A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/06—Electrodes for high-frequency therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating

Definitions

  • the present invention relates to a cosmetic device performing iontophoresis, a method of conduction, and a recording medium.
  • the stratum corneum of the skin has a barrier function to prevent the entry of foreign matter. Therefore, even if the lotion is simply applied to the skin, the water-soluble vitamin C or the like mixed in the lotion is inhibited from penetrating by this barrier function and hardly penetrates to the deep layer of the skin.
  • the active ingredient in the cosmetic water can be penetrated to the deep layer of the skin beyond the barrier layer by utilizing the power of electricity.
  • Patent Document 1 a cosmetic device dedicated for the user to perform the above-described cosmetic treatment is known (see, for example, Patent Document 1).
  • a dedicated cosmetic device or the like as described in Patent Document 1 mentioned above is relatively expensive and difficult to obtain easily.
  • the present invention has been made in view of the above-described point, and has an object of performing reliable ion introduction also by a high frequency AC signal output from an output terminal of a general information processing apparatus.
  • the above problem is, from the first point of view, It is a cosmetic device that performs iontophoresis on human skin, An electrode attached to the skin of the person; An electrical signal formed by superimposing an alternating current signal and a high frequency signal having a frequency higher than that of the alternating current signal, and setting a superimposed position of the high frequency signal in a polarity region not contributing to the ion introduction of the alternating current signal It can be solved by a cosmetic device characterized by having an electrical signal supply means for supplying the electrode.
  • the above-mentioned subject is, from a second viewpoint, In order to introduce ions into human skin, For electrodes attached to the skin of the person, An alternating current signal is superimposed on a high frequency signal having a frequency higher than that of the alternating current signal, and an electric signal formed by setting the overlapping position of the high frequency signal in a polarity region not contributing to the ion introduction of the alternating current signal is supplied. It can be solved by the energization method characterized by the above.
  • the above problem is The problem can be solved by a recording medium formed by recording an electric signal formed by superposing an RF signal having a frequency higher than that of the AC signal on an AC signal.
  • reliable ion introduction can be performed also by a high frequency AC signal output from an output terminal of a general information processing apparatus.
  • FIG. 1 is a block diagram of a cosmetic device according to an embodiment of the present invention.
  • FIG. 2 is a diagram showing a functional configuration of a cosmetic device according to an embodiment of the present invention.
  • FIG. 3 is a diagram showing a hardware configuration of a cosmetic device according to an embodiment of the present invention.
  • FIG. 4 is a diagram showing a waveform of an ion introduction signal used when performing ion introduction in the cosmetic device according to the embodiment of the present invention, together with a waveform as a reference example.
  • FIG. 5 is a figure which shows the alternating current signal and high frequency signal which comprise the signal for ion introduction used when performing ion introduction with the cosmetics apparatus which is one Embodiment of this invention.
  • FIG. 6 is a diagram showing a waveform which is an example of the ion introduction signal.
  • FIG. 7 is a view showing an effect when ion introduction is performed by an ion introduction signal.
  • a content output terminal such as a mobile phone, a personal computer (PC), a portable device (PD), a personal data assistant (PDA), or a game machine
  • a content output terminal such as a mobile phone, a personal computer (PC), a portable device (PD), a personal data assistant (PDA), or a game machine
  • PC personal computer
  • PD portable device
  • PDA personal data assistant
  • game machine It is conceivable to obtain an electrical signal for iontophoresis from an earphone terminal, a dock terminal, a USB (Universal Serial Bus) terminal).
  • USB Universal Serial Bus
  • the standard of the content output terminal of the information processing apparatus is different for each terminal.
  • pulse direct current although it is common to use pulse direct current as an electric signal supplied to an electrode, there are few terminals which can output a pulse direct current signal.
  • an audio signal output from the information processing apparatus usually corresponds to only a frequency in the audible range (20 to 20000 Hz).
  • the waveform is disturbed, and it has been difficult to stably introduce ions.
  • FIG. 1A is a view showing an entire configuration of a cosmetic device 10 according to an embodiment of the present invention
  • FIG. 1B is a cross-sectional view showing a structure of an electrode pad 31 connected to an information processing device 20. is there.
  • the cosmetic device 10 has an information processing device 20 and a cosmetic treatment device 30, as shown in FIG. 1 (A).
  • the information processing apparatus 20 is, for example, a multi-function information terminal apparatus, and can realize various functions by taking in applications, in addition to basic functions such as a telephone function, an Internet connection function, and a music reproduction function.
  • the information processing apparatus 20 which is a multi-function information terminal apparatus, functions as a part of the beauty device 10, and the user (referred to as an ion introduction signal) output from the information processing apparatus 20 is used.
  • the user is not for cosmetic purposes, for example, a mobile phone such as an iPhone (registered trademark) or a smartphone, a PDA such as a PDA, an iPod (registered trademark), or an iPad (registered trademark)
  • a mobile phone such as an iPhone (registered trademark) or a smartphone
  • a PDA such as a PDA, an iPod (registered trademark), or an iPad (registered trademark)
  • the general information processing apparatus which can be carried by can be used, in this invention, it is not limited to this.
  • the specific configuration of the information processing apparatus 20 will be described later for the convenience of description.
  • the beauty treatment apparatus 30 has an electrode pad 31 and an impregnating material 32 which is impregnated with an active ingredient of a cosmetic, a drug solution, or the like (in the following description, a cosmetic solution is described as an example).
  • the electrode pad 31 has a configuration in which carbon sheet electrodes 33A and 33B are provided on each of the insulating base materials 31a and 31b.
  • the carbon sheet electrodes 33A and 33B are connected to the output terminal 20A of the information processing apparatus 20 via the audio cable 34.
  • the output terminal 20A can be a terminal of two or more poles. Specifically, one side of the output terminal 20A is connected to the carbon sheet electrode 33A through the cable 34A, and the other side of the output terminal 20A is connected to the carbon sheet electrode 33B through the cable 34B.
  • an earphone terminal, a dock terminal, a USB (Universal Serial Bus) terminal or the like provided in the information processing device 20 can be used.
  • the impregnating material 32 is made of a water-containing material such as cotton or non-woven fabric.
  • the mask 32 is prepared in various forms corresponding to the site where the ion introduction is desired.
  • worn is shown as an example as the impregnating material 32 (Hereafter, the impregnating material shown in figure is called the mask 32).
  • the component of the cosmetic is an electrolyte, and thus the component is ionized into positive ions and negative ions. Therefore, even if the mask 32 is in a state of being impregnated, the components of the lotion are in a state of being ionized into positive ions and negative ions.
  • the user mounts the cosmetic treatment device 30 on the skin 40 desired to introduce ions.
  • the mask 32 constituting the cosmetic treatment apparatus 30 is first worn on the skin 40 desired to introduce ions.
  • the electrode pad 31 is mounted on the mask 32.
  • the carbon sheet electrodes 33A and 33B are disposed on the electrode pad 31, so that the carbon sheet electrodes 33A and 33B come into contact with the mask 32 impregnated with the lotion in the mounted state.
  • An ion introduction signal output from the information processing apparatus 20 is supplied to the carbon sheet electrode 33A.
  • the iontophoresis signal is supplied to the carbon sheet electrode 33A, a weak current corresponding to the waveform of the iontophoresis signal flows in the skin through the carbon sheet electrodes 33A and 33B, and the skin 40 is repelled by the charge.
  • the waveform and the like of the ion introduction signal will be described in detail later.
  • the information processing apparatus 20 includes an input unit 41, an output unit 42, a recording unit 43, a signal reproduction unit 44, a screen generation unit 45, a network connection unit 46, a control unit 47, and the like.
  • the input unit 41 includes, for example, operation keys such as a mobile phone and a smartphone, a keyboard such as a PC, and a pointing device such as a mouse.
  • the input unit 41 receives input such as start and end of various instructions from the user or the like.
  • the input means 41 may be comprised, for example from audio
  • the output means 42 consists of display screens, such as a display, for example.
  • the output unit 42 displays the content input by the input unit 41 and the content executed based on the input content. At this time, it is also possible to integrally configure the input means 41 and the output means 42 by using a touch panel.
  • the output unit 42 is connected to an output terminal 20A for outputting an audio signal or the like.
  • the cosmetic treatment device 30 described above is connected to the output terminal 20A.
  • the output terminal 20A also includes the above-described Dock terminal and USB terminal.
  • the recording unit 43 records an application program for causing the information processing apparatus 20 to execute various processes, and various data necessary for the processes.
  • Application program for performing ion introduction processing (hereinafter referred to as a program for ion introduction processing) which is the present embodiment, ion introduction signal reproduced by the signal reproduction means 44, user information, operation content data such as ion introduction, treatment Time data and the like are also recorded in the recording means 43.
  • the signal reproduction means 44 reproduces the ion introduction signal recorded in the recording means 43, and outputs this to the cosmetic treatment apparatus 30 via the output means 42 and the output terminal 20A.
  • the signal for introducing ions may be in the form of an audio file such as wav (WAVE) file, AIFF, mp3, mp4, WMA, AAC, RealAudio, MIDI, or AVI, Quic Time, Mpeg-1, Mpeg-2, WMV, It is recorded in the recording means 43 in the form of a moving image file such as FLV.
  • the file format that can be used as the file for this ion introduction signal is generically referred to as content file below.
  • the content file includes audio file and moving picture file.
  • the content file also includes various fills that can be converted into file formats that can be reproduced by the signal reproduction unit 44 by being converted.
  • a content file in which an ion introduction signal is recorded is referred to as an ion introduction signal file.
  • the screen generation unit 45 generates, for example, a menu screen for allowing the user to input treatment content, and a screen for displaying treatment content, treatment progress, treatment result, and the like.
  • the screen generated by the screen generation unit 45 is displayed on a display or the like constituting the output unit 42.
  • the network connection unit 46 is configured to be connectable to a communication network such as the Internet, for example. Therefore, the information processing apparatus 20 can install various programs and various data (including an ion introduction processing program and an ion introduction signal file) to be processed in the information processing apparatus 20 through the network connection unit 46.
  • the various programs and various data installed via the network connection means 46 are recorded in the recording means 43.
  • various data (for example, data regarding iontophoresis) generated in the information processing apparatus 20 may be transmitted to an external device (for example, a server of a cosmetic maker distributing an iontophoresis program, etc.) via a communication network. It is possible.
  • the control unit 47 executes various programs recorded in the recording unit 43 to realize functions corresponding to the programs.
  • the control unit 47 causes the information processing apparatus 20 to function as the beauty device 10 by executing the ion introduction processing program recorded in the recording unit 43.
  • control means 47 executes the ion introduction processing program to reproduce the ion introduction signal file recorded in the recording means 43 in the signal reproduction means 44 to generate an ion introduction signal.
  • This is supplied to the cosmetic treatment apparatus 30 via the output means 42 and the output terminal 20A.
  • the cosmetic treatment apparatus 30 may be provided with a terminal protection means for preventing a fault such as an overcurrent on the output terminal 20A.
  • the output terminal 20A, the output unit 42, the recording unit 43, the signal generation unit 44, and the control unit 47 constitute an electrical signal supply unit described in the claims.
  • FIG. 3 is a diagram showing an example of a hardware configuration for realizing the information processing means.
  • the information processing device 20 includes an input device 51, an output device 52, a drive device 53, an auxiliary storage device 54, a memory device 55, an arithmetic processing unit (CPU) 56, a network connection device 57, and a recording medium. 58 and the like, each of which is configured to be mutually connected by a bus B.
  • the input device 51 includes a keyboard operated by the user, a pointing device such as a mouse, and a touch panel operated by the user, and is used to input various operation instructions from the user.
  • the output device 52 has a display or the like that displays various windows, data, and the like necessary to operate the information processing device 20.
  • the output means 52 also includes an output terminal 20A (earphone terminal, dock terminal, USB terminal, etc.) for outputting sound to a speaker, earphone, etc.
  • the drive device 53 is loaded with the recording medium 58, and reads various programs and various data recorded in the recording medium 58.
  • the various programs and various data read by the drive device 53 are stored in the auxiliary storage device 54.
  • the recording medium 58 on which various programs and various data are recorded is a recording medium or ROM for recording information optically, electrically or magnetically, such as a CD-ROM, a flexible disc, a magneto-optical disc (MO), etc. It is possible to use various types of recording media, such as a semiconductor memory that electrically records information, such as a flash memory.
  • the auxiliary storage device 54 is storage means such as a hard disk.
  • the auxiliary storage device 54 inputs / outputs various files and various data to / from the CPU 56 in accordance with processing of various programs executed by the CPU 56.
  • the memory unit 55 stores an execution program and the like read from the auxiliary storage unit 54 by the CPU 56.
  • the memory device 55 is composed of a ROM, a RAM, and the like.
  • the CPU 56 executes various arithmetic processing, data input / output processing with each hardware configuration unit, control processing of the entire computer, and the like based on a control program such as OS and an execution program stored in the memory device 55. .
  • the network connection device 57 implements the above-described network connection means 46, and is configured to be connectable to a communication network such as the Internet.
  • the cosmetic device 10 uses the information processing device 20 having the above-described hardware configuration.
  • the information processing apparatus 20 there is no hardware configuration added particularly for performing the ion introduction process. Therefore, the information processing apparatus 20 can use a multifunctional information terminal device that is usually marketed as it is.
  • the ion introduction processing program and the ion introduction signal file are installed in the information processing apparatus 20, and the beauty treatment apparatus 30 is connected to the information processing apparatus 20.
  • the treatment device 30 is made to function as a cosmetic device 10 capable of performing iontophoresis.
  • the program for ion introduction processing and the signal file for ion introduction installed in the information processing apparatus 20 are installed from the provision server via the communication network, if there is a provision server providing the program and the file. If the recording medium 58 is provided by being recorded on a recording medium 58 such as a CD-ROM, the recording medium 58 may be installed by being read by the drive device 53. Furthermore, it may be pre-installed when manufacturing the information processing apparatus 20.
  • FIG. 4A shows a signal waveform of an ion introduction signal according to an embodiment of the present invention.
  • 4B shows the signal waveform of the ion introduction signal according to the first reference example
  • FIG. 4C shows the signal waveform of the ion introduction signal according to the second reference example. There is.
  • active ingredients such as cosmetics and medicines are electrolytes, and when ions are introduced into human skin, depending on the type, either plus (+) or minus (-) of AC pulse signal
  • the polar region contributes to iontophoresis, while the other polar region does not contribute to iontophoresis.
  • the negative (-) polarity region is described as contributing to the ion introduction.
  • the ion introduction signal according to the first reference example shown in FIG. 4 (B) will be described.
  • the ion introduction signal according to the first reference example is a low frequency AC pulse signal having a signal frequency of 1 Hz or less.
  • the ion introduction signal according to the first reference example is conventionally used as a signal for ion introduction.
  • the period becomes long, so the positive (+) polarity region and the negative (-) polarity region of AC pulse signal per one time
  • the time you are shaking in the area will be longer. That is, in the signal for ion introduction, the time T1 per time of the negative (-) polarity region contributing to the ion introduction becomes long. Therefore, the active ingredient moves to the inside of the skin and easily penetrates the inside of the skin, so that iontophoresis can be favorably performed.
  • the time of the region contributing to ion introduction in the signal for ion introduction is referred to as ion introduction contribution time.
  • the output terminal 20A of the multifunctional information terminal device which is the information processing device 20 does not correspond to the low frequency signal of 1 Hz or less, and thus such low frequency from the information processing device 20 to the beauty treatment device 30 As described above, it is difficult to supply a signal for iontophoresis.
  • the signal for ion introduction according to the second reference example shown in FIG. 4C has a frequency in the audible range of greater than 1 Hz, for example, about 20 to 20000 Hz. Therefore, the signal for ion introduction shown in FIG. 4C is a frequency higher than the frequency generally used as the ion introduction signal shown in FIG. 4B.
  • the time T2 (ion introduction contribution time) of the region contributing to the ion introduction in the ion introduction signal is shown in FIG. It becomes short compared with iontophoresis contribution time T1 (T2 ⁇ T1). Therefore, for example, even if the active ingredient moves in the inward direction of the skin during the iontophoretic contribution time T2 to which an alternating current pulse signal in the minus (-) polarity region is applied, the plus of the opposite polarity is An AC pulse signal in the (+) polarity region is applied, and the active ingredient moves to the opposite side to the inward direction of the skin.
  • the ion introduction processing is performed using the ion introduction signal having a frequency higher than 1 Hz, the ion introduction contribution time T2 is short, and thus, the ion introduction signal shown in FIG. , The efficiency of iontophoresis decreases.
  • the signal for ion introduction according to the present embodiment is an alternating current in a polar region (in the present embodiment, a region of positive polarity) which does not contribute to the ion introduction of an alternating current pulse signal.
  • a signal waveform is obtained by superimposing a high frequency signal having a frequency higher than that of the pulse signal.
  • the signal for ion introduction in the present embodiment shown in FIG. 4A has a configuration in which a high frequency signal as a noise signal is superimposed on a polar region that does not contribute to the ion introduction of the signal for ion introduction shown in FIG. It can be done.
  • FIG. 5 is a diagram showing an AC pulse signal constituting an ion introduction signal according to the present embodiment and a high frequency signal separately.
  • FIG. 5A shows an alternating pulse signal.
  • the AC pulse signal shown in FIG. 5A is an AC signal which can be output from a general information processing apparatus, for example, the lower limit value exceeds 1 Hz and the upper limit is an audible frequency.
  • the frequency of the AC pulse signal is an AC signal whose frequency f is in the range of 1 Hz ⁇ f ⁇ 20,000 Hz.
  • FIG. 5B shows a high frequency signal to be superimposed on an alternating current pulse signal.
  • This high frequency signal is a burst-like direct current pulse signal, and its frequency may be, for example, 5 to 20 times that of the alternating current pulse signal, for example, about 10 times the frequency.
  • the amplitude of this high frequency signal can be smaller than that of the AC pulse signal, for example, 1/10 or more and less than 1.
  • the amplitude E1 of this AC pulse signal, the amplitude value E2 of the high frequency signal, and the constant value (0.125 in the above example) to be multiplied are appropriately determined according to the ion characteristics included in the lotion, the condition of the skin to be ionized, etc. It is adjusted.
  • the waveform for ion introduction which concerns on this embodiment shown to FIG. 4 (A) is produced
  • the ion introduction signal file storing the ion introduction waveform may be installed in the information processing apparatus 20 using a communication network.
  • the signal file for ion introduction may be stored in a recording medium such as a CD-ROM, and may be installed by mounting it on the information processing apparatus 20.
  • the ion introduction signal file according to the present embodiment shown in FIG. 4A is obtained by reproducing the ion introduction signal file installed as described above.
  • the first signal generating means for generating the alternating current pulse signal shown in FIG. 5A and the second signal generating means for generating the high frequency signal shown in FIG. The configuration for generating the iontophoresis waveform according to the present embodiment shown in FIG. 4 (A) in the information processing apparatus 20 by internally providing signal combining means for superimposing the signals generated by the respective signal generating means. It is also possible.
  • a pulse signal is described as an example of the signal waveform.
  • the signal waveform of the ion introduction signal according to the present embodiment is not limited to the pulse signal, and application to other signal waveforms such as a sine wave signal is also possible.
  • the ion introduction contribution time T3 to which the AC pulse signal in the negative (-) polarity region is applied is the ion introduction shown in FIG. 4 (C).
  • the contribution time T2 in the plus (+) polarity region of the opposite polarity, the high frequency signal is superimposed to become noise, and the plus (+) AC pulse signal of the opposite polarity is canceled or reduced. Become so. Thereby, the movement of the active ingredient to the opposite side to the inward direction of the skin can be inhibited, and the active ingredient can be moved to the inside of the skin and easily penetrated into the inside of the skin.
  • the high frequency signal is further superimposed on the polarity side which does not contribute to ion introduction. Movement in the direction opposite to the infiltration direction can be suppressed to enhance the infiltration effect of the active ingredient.
  • the mask 32 was impregnated with 4 MSK (4-methoxysalicylic acid potassium salt: 1%, pH 6 which is a derivative of salicylic acid) having melanin formation suppression and elimination effects as a drug for iontophoresis.
  • MSK 4-methoxysalicylic acid potassium salt: 1%, pH 6 which is a derivative of salicylic acid
  • iontophoresis was performed on the face of four panels.
  • the electrode pad 31 (see FIG. 1) is attached to the mask 32 attached to the face of the panel, and the information terminal 20 outputs the output terminal 20A and the audio cable 34.
  • the ion introduction signal according to the present embodiment was supplied to the carbon sheet electrodes 33A and 33B via the
  • FIG. 6 shows the ion introduction signal according to the present embodiment used in the present experiment.
  • the ion introduction signal shown in the figure uses a sine wave signal having a frequency f in the range of 1 Hz ⁇ f ⁇ 20,000 Hz as an alternating current signal, and in a polar region (region indicated by a broken arrow in the figure) not contributing to the ion introduction.
  • a high frequency signal higher in frequency than the alternating current signal was superimposed.
  • the frequency of the AC signal is 100 Hz
  • the frequency of the high frequency signal is 1000 Hz.
  • the information processing device 20 for supplying the above-described ion introduction signal to the beauty treatment device 30 an iPhone (registered trademark) was used, and the beauty treatment device 30 was connected to the output terminal of the iPhone.
  • the ion introduction site was a human face, and the voltage applied to the carbon sheet electrodes 33A and 33B was ⁇ 1.5 V (3 Vpp).
  • the polarity to superimpose the high frequency signal is switched every 50 seconds.
  • penetration of negative ions is promoted from one electrode (for example, the carbon sheet electrode 33A), and conversely, when high frequency signals are superimposed on the negative electrode side, The negative ions are promoted from the other electrode (for example, the carbon sheet electrode 33B).
  • ion introduction effect after the ion introduction process was performed as follows. First, the site subjected to the iontophoresis treatment was washed with soap, and subsequently, the iontophoresis site was subjected to the ion lead-out treatment (treatment to extract the drug subjected to the iontophoresis treatment again).
  • This ion lead-out process is a process opposite to iontophoresis, and is a process for drawing out the ions introduced into the skin 40 from the skin 40 by applying a potential of the opposite polarity to the ions introduced into the skin 40.
  • FIG. 7 shows the result.
  • FIG. 7 shows the average value of each experimental result of 4 panels.
  • a solid background indicates the result of performing ion introduction using the ion introduction signal including the high frequency signal according to the present embodiment and then extracting the ion (shown as an example).
  • the white outline shows the result of sticking out the mask impregnated with the drug without ion introduction, and the ion derivation thereafter (shown as a reference example).
  • the amount of drug that is ion-guided after iontophoresis using an iontophoresis signal that includes a high frequency signal is greater than the amount of ion-guided drug that is simply applied without the iontophoresis. (P ⁇ 0.01 paired-t-test). Specifically, the penetration effect is improved by about 1.4 times in the case of using an ion introduction signal including a high frequency signal as compared with the case in which the ion introduction is not performed.
  • the frequency of the alternating current signal may be 1 Hz or less. Even if the frequency of the AC signal is 1 Hz or less, the penetration effect of the active ingredient can be enhanced by superimposing the high frequency signal which is a noise signal on the polarity region which does not contribute to the ion introduction of the ion introduction signal.

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PCT/JP2013/075730 2012-10-05 2013-09-24 美容機器、通電方法及び記録媒体 Ceased WO2014054459A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP13843096.2A EP2905048A4 (en) 2012-10-05 2013-09-24 COSMETIC DEVICE, POWER SUPPLY METHOD AND RECORDING MEDIUM
CN201380051019.2A CN104684612B (zh) 2012-10-05 2013-09-24 美容设备
US14/430,977 US9981125B2 (en) 2012-10-05 2013-09-24 Cosmetic device, method of applying current, and storage medium
KR1020157008243A KR101571450B1 (ko) 2012-10-05 2013-09-24 미용 기기, 통전 방법 및 기록 매체
HK15105640.6A HK1205027B (en) 2012-10-05 2013-09-24 Cosmetic device

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JP2012223698A JP5580383B2 (ja) 2012-10-05 2012-10-05 美容機器及び通電方法及び記録媒体
JP2012-223698 2012-10-05

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KR20150045521A (ko) 2015-04-28
US20150246227A1 (en) 2015-09-03
US9981125B2 (en) 2018-05-29
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KR101571450B1 (ko) 2015-11-24
CN104684612A (zh) 2015-06-03

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