WO2014008351A3 - Andrographis paniculata compositions and methods for treatment of addictions - Google Patents

Andrographis paniculata compositions and methods for treatment of addictions Download PDF

Info

Publication number
WO2014008351A3
WO2014008351A3 PCT/US2013/049246 US2013049246W WO2014008351A3 WO 2014008351 A3 WO2014008351 A3 WO 2014008351A3 US 2013049246 W US2013049246 W US 2013049246W WO 2014008351 A3 WO2014008351 A3 WO 2014008351A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
treatment
methods
addictions
andrographis paniculata
Prior art date
Application number
PCT/US2013/049246
Other languages
French (fr)
Other versions
WO2014008351A2 (en
Inventor
Roberto Ciccocioppo
Original Assignee
Omeros Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omeros Corporation filed Critical Omeros Corporation
Priority to AU2013286711A priority Critical patent/AU2013286711A1/en
Priority to CA2878402A priority patent/CA2878402A1/en
Priority to JP2015520672A priority patent/JP2015522038A/en
Priority to EP13813082.8A priority patent/EP2866817A4/en
Publication of WO2014008351A2 publication Critical patent/WO2014008351A2/en
Publication of WO2014008351A3 publication Critical patent/WO2014008351A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/40—Cornaceae (Dogwood family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Addiction (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Methods and compositions for the treatment or prevention of addictions and impulse control disorders using Andrographis paniculata, active substances contained therein and extracts thereof, alone or in combination with other therapeutic agents. The methods and compositions of the invention are useful in the treatment or prevention of addiction to substances, including alcohol, nicotine, marijuana, opioid agonists cocaine, and amphetamines, as well as impulse control disorders, including pathological gambling and pathological overeating.
PCT/US2013/049246 2012-07-06 2013-07-03 Andrographis paniculata compositions and methods for treatment of addictions WO2014008351A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2013286711A AU2013286711A1 (en) 2012-07-06 2013-07-03 Andrographis paniculata compositions and methods for treatment of addictions
CA2878402A CA2878402A1 (en) 2012-07-06 2013-07-03 Andrographis paniculata compositions and methods for treatment of addictions
JP2015520672A JP2015522038A (en) 2012-07-06 2013-07-03 Andrographis paniculata composition and method for the treatment of addiction
EP13813082.8A EP2866817A4 (en) 2012-07-06 2013-07-03 Andrographis paniculata compositions and methods for treatment of addictions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261668909P 2012-07-06 2012-07-06
US61/668,909 2012-07-06

Publications (2)

Publication Number Publication Date
WO2014008351A2 WO2014008351A2 (en) 2014-01-09
WO2014008351A3 true WO2014008351A3 (en) 2014-02-27

Family

ID=49882602

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/049246 WO2014008351A2 (en) 2012-07-06 2013-07-03 Andrographis paniculata compositions and methods for treatment of addictions

Country Status (6)

Country Link
US (1) US20140072662A1 (en)
EP (1) EP2866817A4 (en)
JP (1) JP2015522038A (en)
AU (1) AU2013286711A1 (en)
CA (1) CA2878402A1 (en)
WO (1) WO2014008351A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170173039A1 (en) * 2014-04-02 2017-06-22 Yale University Compositions and methods to treat addiction
SE540630C2 (en) 2016-12-30 2018-10-09 3Eflow Ab A method and apparatus for flow measurement in a fluid distribution system having a number of fluid tap units
WO2018126303A1 (en) 2017-01-05 2018-07-12 Philippe Kriwin Composition for treating alcohol addiction
JP2018177723A (en) * 2017-04-18 2018-11-15 株式会社マザー＆チャイルド Aromatic composition comprising effects of suppression of impulsivity of men and relaxation
WO2019221177A1 (en) * 2018-05-15 2019-11-21 青木 勇 Prophylactic and/or therapeutic drug for dependence
WO2020002971A1 (en) 2018-06-26 2020-01-02 Gervais, Christian Use of co2 generating agent for the treatment of alcohol addiction
US20210275494A1 (en) * 2018-07-16 2021-09-09 Regents Of The University Of Colorado, A Body Corporate Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease
US10966938B2 (en) 2019-01-04 2021-04-06 Jonand4, Llc Composition and method for preventing or treating hangover symptoms
CN111920802B (en) * 2020-09-11 2024-01-23 华侨大学 Application of andrographolide in preparing medicament for preventing and treating adult T cell leukemia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001022934A2 (en) * 1999-09-24 2001-04-05 Yng Wong Quing Non Delivery of small doses of ingestible treatments
WO2006131932A1 (en) * 2005-06-09 2006-12-14 Mmi Corporation Herbal formulation capable of preventing alcohol-induced hangover, methods of preparing the same and use thereof
US20110034565A1 (en) * 2008-04-18 2011-02-10 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229120A (en) * 1992-02-05 1993-07-20 Devincent James F Treatment for cocaine abuse
JP2000355538A (en) * 1999-04-15 2000-12-26 Kanegafuchi Chem Ind Co Ltd Receptor agonist responsive to peroxisome activator
US20050090457A1 (en) * 2002-02-15 2005-04-28 N.V. Nutricia Method of treating mammals with genistein and/or genistein analogues
US20040180104A1 (en) * 2003-03-11 2004-09-16 Lin Chih Hui Herbal composition for preventing and/or treating conditions in associated with depression
AU2004315105A1 (en) * 2004-02-03 2005-08-18 Universidad Austral De Chile Composition of labdane diterpenes extracted from Andrographis paniculata, useful for the treatment of autoimmune diseases, and Alzheimer disease by activation of PPR-gamma receptors
CN1634402A (en) * 2004-10-06 2005-07-06 刘起麟 Effective capsule capable of radically curing drug addiction
CN1927328A (en) * 2005-09-09 2007-03-14 王向东 Traditional Chinese medicine composition for treating hemorrhoid, anus and pudendum disease and its using method
US7741367B2 (en) * 2006-02-08 2010-06-22 Virginia Tech Intellectual Properties, Inc. Method of using abscisic acid to treat diseases and disorders
US9308198B2 (en) * 2006-09-08 2016-04-12 Rhode Island Hospital Treatment, prevention, and reversal of alcohol-induced brain disease
CN110403942A (en) * 2007-04-11 2019-11-05 奥默罗斯公司 Prevent and treat the composition and method of habituation
AU2010224037B2 (en) * 2009-03-11 2015-02-05 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
JP2009046481A (en) * 2008-07-30 2009-03-05 Kaneka Corp Peroxisome proliferator-activated receptor ligand agent
KR20120002367A (en) * 2010-06-30 2012-01-05 한국식품연구원 Anti diabetes composition comprising biochanin a as active ingredient

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001022934A2 (en) * 1999-09-24 2001-04-05 Yng Wong Quing Non Delivery of small doses of ingestible treatments
WO2006131932A1 (en) * 2005-06-09 2006-12-14 Mmi Corporation Herbal formulation capable of preventing alcohol-induced hangover, methods of preparing the same and use thereof
US20110034565A1 (en) * 2008-04-18 2011-02-10 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHAMBRIER ET AL.: "Eicosapentaenoic Acid Induces mRNA Expression of Peroxisome Proliferator-Activated Receptor gamma", OBESITY RESEARCH, vol. 10, no. 6, 6 June 2002 (2002-06-06), pages 518 - 525, XP055184431 *
EARLEYWINE ET AL.: "Personality risk for alcoholism covaries with hangover symptoms", ADDICTIVE BEHAVIORS, vol. 18, 1993, pages 415 - 420, XP055184432 *
See also references of EP2866817A4 *
TAKAHASHI ET AL.: "Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes", FEBS LETTERS, vol. 514, 15 February 2002 (2002-02-15), pages 315 - 322, XP004347719 *

Also Published As

Publication number Publication date
US20140072662A1 (en) 2014-03-13
WO2014008351A2 (en) 2014-01-09
EP2866817A4 (en) 2016-04-20
CA2878402A1 (en) 2014-01-09
JP2015522038A (en) 2015-08-03
AU2013286711A1 (en) 2015-02-26
EP2866817A2 (en) 2015-05-06

Similar Documents

Publication Publication Date Title
WO2014008351A3 (en) Andrographis paniculata compositions and methods for treatment of addictions
WO2012062925A3 (en) Compounds and methods for treating pain
WO2014152029A3 (en) Oxazolo[5,4-c]quinolin-2-one compounds as bromodomain inhibitors
WO2012064973A3 (en) Heterocyclic compounds and uses thereof
WO2009089494A3 (en) Pharmaceutical compositions
WO2012024620A3 (en) Autotaxin inhibitors and uses thereof
WO2012037410A3 (en) Estrogen receptor modulators and uses thereof
WO2011156518A3 (en) Estrogen receptor modulators and uses thereof
WO2014031610A8 (en) Methods for treating or preventing asthma by administering an il-4r antagonist
WO2013012915A8 (en) Heterocyclic compounds and uses thereof
WO2012078593A3 (en) Lysophosphatidic acid receptor antagonists and their use in the treatment fibrosis
WO2013061161A3 (en) New combination therapies for treating neurological disorders
WO2007098281A3 (en) Oxysterol compounds and the hedgehog pathway
WO2011041462A3 (en) Polycyclic compounds as lysophosphatidic acid receptor antagonists
WO2011103202A3 (en) Androgen receptor modulators and uses thereof
WO2012032209A3 (en) Pharmaceutical composition for the treatment of dry eye
WO2011041694A3 (en) Compounds as lysophosphatidic acid receptor antagonists
WO2011017350A3 (en) Compounds as lysophosphatidic acid receptor antagonists
BRPI1012128A2 (en) compositions containing berberine or their analogues for the treatment of rosacea or red-face related skin disorders.
BRPI1013705A2 (en) compounds, pharmaceutical composition, method of treating disease or condition associated with trap1 function and uses of compounds and pharmaceutical composition
WO2013070615A8 (en) Combination therapies using anti- pseudomonas psl and pcrv binding molecules
WO2012064667A3 (en) Treatment of addiction and impulse-control disorders using pde7 inhibitors
WO2012007847A3 (en) Pharmaceutical compositions and methods of treatment
MX2012004078A (en) Compounds and compositions as modulators of gpr119 activity.
WO2012125981A3 (en) Raf kinase inhibitors

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13813082

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 2015520672

Country of ref document: JP

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2878402

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2013813082

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2013286711

Country of ref document: AU

Date of ref document: 20130703

Kind code of ref document: A

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13813082

Country of ref document: EP

Kind code of ref document: A2