WO2013135120A1 - 获取生理信号周期的方法及系统 - Google Patents
获取生理信号周期的方法及系统 Download PDFInfo
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- WO2013135120A1 WO2013135120A1 PCT/CN2013/071291 CN2013071291W WO2013135120A1 WO 2013135120 A1 WO2013135120 A1 WO 2013135120A1 CN 2013071291 W CN2013071291 W CN 2013071291W WO 2013135120 A1 WO2013135120 A1 WO 2013135120A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1102—Ballistocardiography
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
- A61B5/1135—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing by monitoring thoracic expansion
Definitions
- the invention relates to a physiological signal acquisition technology, in particular to a method and a system for acquiring a physiological signal period.
- the important physiological signals of the human body such as heartbeat, breathing and other signals, were mainly obtained by collecting and processing the muscle electrical signals.
- the signal acquisition device needs to be in close contact with the human skin to obtain a clear electrical signal, and then amplified and processed.
- the period of the physiological signal obtained by the above method can be firstly shaped by a simple threshold setting, and the flag associated with the period is obtained, and is calculated according to the period flag.
- the main object of the present invention is to provide a method for acquiring a physiological signal period, which improves the efficiency of physiological signal period acquisition and reduces the acquisition cost.
- the invention provides a method for acquiring a physiological signal period, comprising the steps of:
- the physiological signal period is obtained by calculating the time value between one extreme value and the next extreme value.
- the method further comprises:
- the average of the two periods is set to the physiological signal period.
- the received physiological signal value is compared with the temporary storage value, and one of them is retained; the physiological signal value whose maintenance time reaches the set time is determined as an extreme value; the cycle is restarted, and the step of determining the next extreme value is specifically include:
- the step of obtaining a physiological signal period by calculating a time value between an extreme value and a next extreme value comprises:
- the time required to accumulate the accumulated value in the accumulator b is added to the set time to obtain the physiological signal period.
- the set time is greater than a half period of the upper limit of the physiological signal period identification range.
- the invention also provides a system for acquiring a physiological signal period, comprising:
- the extreme value determining unit is configured to receive the physiological signal value and the temporary storage value to compare the size, and retain one of the physiological signal values that have reached the set time; the cycle is restarted to determine the next extreme value;
- a period calculation unit is configured to obtain a physiological signal period by calculating a time value between an extreme value and a next extreme value.
- the system further comprises:
- the similar period judging unit is configured to judge whether the periods acquired by the maximum value and the minimum value are close to each other within a period of time;
- the period setting unit is configured to set the average value of the two periods to the physiological signal period when they are close.
- the extreme value determining unit is specifically configured to:
- the period calculation unit specifically includes:
- the time required to accumulate the accumulated value in the accumulator b is added to the set time to obtain the physiological signal period.
- the set time is greater than a half period of the upper limit of the physiological signal period identification range.
- the invention can obtain the cycle of the physiological signal through the extreme value recognition algorithm, and has the advantages of simplicity, rapidity, high efficiency and high reliability; and the requirements for the amplification, filtering and analog-to-digital conversion of the physiological signal are relatively low, and the data processing is relatively easy. Can greatly reduce hardware (requirement) overhead.
- FIG. 1 is a schematic diagram of signal waveforms acquired by a piezoelectric sensor in the prior art
- FIG. 2 is a schematic diagram of a waveform of a bioelectric signal in the prior art
- FIG. 3 is a schematic flow chart of steps in an embodiment of a method for acquiring a physiological signal period according to the present invention
- FIG. 4 is a schematic flow chart of steps in another embodiment of a method for acquiring a physiological signal period according to the present invention.
- FIG. 5 is a schematic structural diagram of an embodiment of a system for acquiring a physiological signal period according to the present invention
- FIG. 6 is a schematic structural view of another embodiment of a system for acquiring a physiological signal period according to the present invention.
- the method can include:
- Step S10 comparing the received physiological signal value with the temporary storage value, retaining one of them; determining the physiological signal value whose maintenance time reaches the set time as an extreme value; restarting the cycle to determine the next extreme value;
- Step S11 Obtain a physiological signal period by calculating a time value between an extreme value and a next extreme value.
- the physiological signal may include a signal such as a breath and a heartbeat, and the physiological signal value may be a specific value such as a voltage value; and the physiological signal may be acquired by a device such as a piezoelectric sensor.
- a micro-motion sensor device such as a piezoelectric sensor can be used to acquire a fretting signal when the human body is quiet, and a physiological signal period of breathing and/or heartbeat can be directly interpreted in the carrier signal.
- the step S10 may specifically include: receiving a physiological signal value, starting the counter a and adding a unit value, and comparing the physiological signal value with the temporary storage value, when the physiological signal value is greater than/less than the temporary storage value, Substituting the physiological signal value for the temporary storage value, and accumulating the value in the counter a to the accumulator b, clearing the counter a; when the physiological signal value is less than/greater than the temporary storage value, continuing to receive the next heartbeat signal voltage Value; when the counter a reaches the value corresponding to the set time, it can be determined that the physiological signal value is an extreme value; then the accumulated value in the accumulator b is output, and then the counter a, the temporary register and the accumulation are cleared. Br, and continue to determine the next extreme value.
- the temporary value can be zero or a retained physiological signal value.
- the above step S11 may specifically include: adding the time required for the accumulated value in the accumulator b to the set time to obtain the physiological signal period.
- the obtaining of the physiological signal period may be performed by an extreme value recognition algorithm, and the extreme value may include a maximum value and a minimum value, that is, the one extreme value and the next extreme value may be maximum values or minimum values, respectively.
- the maximal value recognition algorithm can be used to keep a certain received physiological signal value from being overtaken. When the timer reaches the set time, the physiological signal value is considered to be a maximum value in one cycle. Also, a time (length) value between when a certain maximum value (one extreme value) is identified and the next maximum value (the next extreme value) is recognized can be calculated.
- the minimum value identification algorithm can be used to keep the value of a received physiological signal from being over-timed.
- the physiological signal value is considered to be a minimum value in one cycle. Also, a time (length) value between when a certain minimum value (one extreme value) is identified and the next minimum value (the next extreme value) is recognized can be calculated. Then, according to the set time and the time value between the two maximum values or the time value between the two extreme values, the physiological signal period acquired by the maximum value recognition algorithm and the physiological state acquired by the minimum value recognition algorithm are respectively obtained. Signal period.
- the set time can be set according to the specific condition of the physiological signal. For example, in the embodiment, the set time can be set to be greater than half of the physiological signal period.
- the following is an example of obtaining a heartbeat signal cycle in a maximum value manner, and further describes the method for obtaining a physiological signal cycle as described above.
- the piezoelectric sensor can receive a voltage value of the heartbeat signal output by the piezoelectric sensor, start the counter a plus 1, and compare it with the temporary value in the register through the comparator; when it is greater than the temporary value, replace it with the temporary storage The value is added to the accumulator b in the counter a, and the counter a is cleared; when it is less than the temporary value, the next heartbeat signal voltage is continuously received.
- the heartbeat signal voltage values received by the cycle start Compare with the scratch value zero in the scratchpad.
- the above formula for calculating the heartbeat signal period can be:
- Cycle (s) (value in accumulator b / reception speed) + set time.
- the upper limit of the recognition period can be the reciprocal of the set time.
- the set time of the maximum value can be set to 0.55 seconds (the set time constant of the minimum value can be 0.60 seconds), when a certain received heartbeat signal voltage The value is maintained in the scratchpad for 0.55 seconds and is not exceeded, then the counter a starts counting.
- the counter a When there is a newly received heartbeat signal voltage value entering the comparator, the counter a is incremented by one; if the newly received heartbeat signal voltage value is greater than the previous temporary storage value, the newly received heartbeat signal voltage value is updated to the temporary register, instead of before The heartbeat signal voltage value in the register, the count of the counter a is accumulated in the accumulator b, and the counter a is cleared; if the newly received heartbeat signal voltage value is less than or equal to the temporary value in the previous register, then the counter a Adding 1 other than the other, continue the comparison cycle of the heartbeat signal voltage value; until the count value of the counter a reaches 0.55 seconds of the received heartbeat signal voltage value (such as 300), the value B of the accumulator b is output, and then The time taken to accumulate to B plus 0.55 seconds is the period of the heartbeat signal.
- 0.55 seconds of the received heartbeat signal voltage value such as 300
- the physiological signal period of the maximum value mode and the physiological signal period of the minimum value mode are respectively obtained, and then the physiological signal period and the minimum value physiological signal according to the maximum value mode are obtained.
- the cycle further captures a more accurate physiological signal cycle.
- the method for acquiring a period of a physiological signal may further include:
- Step S12 determining whether the periods acquired by the maximum value and the minimum value are close to each other within a period of time;
- step S13 when they are close, the average value of the two periods is determined as the physiological signal period.
- At least one physiological signal period can be obtained by each of the maximum value method and the minimum value method. Then, the physiological signal cycles obtained by the two methods are compared to determine whether the two cycles are similar; when the two are similar, the average of the two cycles is calculated, and the average value is determined as a more accurate physiological signal cycle; otherwise, it ends.
- the similar determination may be determined according to the specific situation of the physiological signal. For example, the similar range of the respiratory signal period is: the difference is about 0.004 seconds, and the similar range of the heartbeat signal period is: the difference is about 0.017 seconds.
- the method for obtaining the physiological signal period can obtain the cycle of the physiological signal through the extreme value recognition algorithm, and has the advantages of simplicity, rapidity, high efficiency and high reliability; and the requirements for amplification, filtering and analog-to-digital conversion of the physiological signal are relatively low. Data processing is also relatively easy, which can greatly reduce hardware overhead.
- the system 20 may include: an extreme value determining unit 21 and a period calculating unit 22; the extreme value determining unit 21 is configured to receive a physiological signal value and a temporary storage value to compare the size, and retain one of them; and maintain the maintaining time to a set time.
- the physiological signal value is determined as an extreme value; the cycle is restarted, and the next extreme value is determined; the cycle calculating unit 22 is configured to acquire the physiological signal period by calculating a time value between one extreme value and the next extreme value.
- the physiological signal may include a signal such as a breath and a heartbeat, and the physiological signal value may be a specific value such as a voltage value; and the physiological signal may be acquired by a device such as a piezoelectric sensor.
- the micro-motion sensor device such as a piezoelectric sensor can be used to acquire the fretting signal when the human body is quiet, and the physiological signal period of the breathing and/or the heartbeat can be directly interpreted in the carrier signal.
- the extreme value determining unit 21 is specifically configured to: receive a physiological signal value, start the counter a plus a unit value, and compare the physiological signal value with the temporary storage value, when the physiological signal value is greater than/less than the temporary storage value.
- the physiological signal value is substituted for the temporary storage value, and the value in the counter a is accumulated in the accumulator b, and the counter a is cleared; when the physiological signal value is less than/larger than the temporary storage value, the next heartbeat is continuously received.
- Signal voltage value when the counter a reaches the value corresponding to the set time, it can be determined that the physiological signal value is an extreme value; then the accumulated value in the accumulator b is output, and the counter a and the register are cleared. And accumulator b, and continue to determine the next extreme value.
- the temporary value can be zero or a retained physiological signal value.
- the period calculation unit 22 specifically includes: adding the time required for the accumulated value in the accumulator b to the set time to acquire the physiological signal period.
- the obtaining of the physiological signal period may be performed by an extreme value recognition algorithm, and the extreme value may include a maximum value and a minimum value, that is, the one extreme value and the next extreme value may be maximum values or minimum values, respectively.
- the maximal value recognition algorithm can be used to keep a certain received physiological signal value from being overtaken. When the timer reaches the set time, the physiological signal value is considered to be a maximum value in one cycle. Also, a time (length) value between when a certain maximum value (one extreme value) is identified and the next maximum value (the next extreme value) is recognized can be calculated.
- the minimum value identification algorithm can be used to keep the value of a received physiological signal from being over-timed.
- the physiological signal value is considered to be a minimum value in one cycle. Also, a time (length) value between when a certain minimum value (one extreme value) is identified and the next minimum value (the next extreme value) is recognized can be calculated. Then, according to the set time and the time value between the two maximum values or the time value between the two extreme values, the physiological signal period acquired by the maximum value recognition algorithm and the physiological state acquired by the minimum value recognition algorithm are respectively obtained. Signal period.
- the set time can be set according to the specific condition of the physiological signal. For example, in the embodiment, the set time can be set to be greater than half of the physiological signal period.
- the following takes the period of the heartbeat signal as a maximum value as an example, and further details the system 20 for obtaining the physiological signal period.
- the piezoelectric sensor can receive a voltage value of the heartbeat signal output by the piezoelectric sensor, start the counter a plus 1, and compare it with the temporary value in the register through the comparator; when it is greater than the temporary value, replace it with the temporary storage The value is added to the accumulator b in the counter a, and the counter a is cleared; when it is less than the temporary value, the next heartbeat signal voltage is continuously received.
- the heartbeat signal voltage values received by the cycle start Compare with the scratch value zero in the scratchpad.
- the above formula for calculating the heartbeat signal period can be:
- Cycle (s) (value in accumulator b / reception speed) + set time.
- the upper limit of the recognition period can be the reciprocal of the set time.
- the set time of the maximum value can be set to 0.55 seconds (the set time constant of the minimum value can be 0.60 seconds), when a certain received heartbeat signal voltage The value is maintained in the scratchpad for 0.55 seconds and is not exceeded, then the counter a starts counting.
- the counter a When there is a newly received heartbeat signal voltage value entering the comparator, the counter a is incremented by one; if the newly received heartbeat signal voltage value is greater than the previous temporary storage value, the newly received heartbeat signal voltage value is updated to the temporary register, instead of before The heartbeat signal voltage value in the register, the count of the counter a is accumulated in the accumulator b, and the counter a is cleared; if the newly received heartbeat signal voltage value is less than or equal to the temporary value in the previous register, then the counter a Adding 1 other than the other, continue the comparison cycle of the heartbeat signal voltage value; until the count value of the counter a reaches 0.55 seconds of the received heartbeat signal voltage value (such as 300), the value B of the accumulator b is output, and then The time taken to accumulate to B plus 0.55 seconds is the period of the heartbeat signal.
- 0.55 seconds of the received heartbeat signal voltage value such as 300
- the heartbeat signal period (B/500) + 0.55.
- the physiological signal period of the maximum value mode and the physiological signal period of the minimum value mode are respectively obtained, and then the physiological signal period and the minimum value physiological signal according to the maximum value mode are obtained.
- the cycle further captures a more accurate physiological signal cycle.
- the system 20 may further include: a close period judging unit 23 and a period setting unit 24; and the close period judging unit 23 is configured to judge the maximum value through a period of time. Whether the period acquired separately from the minimum value is similar; the period setting unit 24 is configured to set the average value of the two periods to the physiological signal period when they are close.
- At least one physiological signal period can be obtained by each of the maximum value method and the minimum value method. Then, the physiological signal cycles obtained by the two methods are compared to determine whether the two cycles are similar; when the two are similar, the average of the two cycles is calculated, and the average value is determined as a more accurate physiological signal cycle; otherwise, it ends.
- the similar determination may be determined according to the specific situation of the physiological signal. For example, the similar range of the respiratory signal period is: the difference is about 0.004 seconds, and the similar range of the heartbeat signal period is: the difference is about 0.017 seconds.
- the system 20 for obtaining the physiological signal period can obtain the cycle of the physiological signal through the extreme value recognition algorithm, and has the advantages of simplicity, rapidity, high efficiency and high reliability; and the requirements for the amplification, filtering and analog-to-digital conversion of the physiological signal are correspondingly compared. Low, data processing is also relatively easy, reducing hardware requirements.
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Claims (10)
- 一种获取生理信号周期的方法,其特征在于,包括步骤:接收生理信号值与暂存数值比较大小,保留其中之一;将维持时间达到设定时间的生理信号值判定为一个极值;重新开始循环,判定下一个极值;通过计算一个极值至下一个极值之间的时间值,获取生理信号周期。
- 根据权利要求1所述的获取生理信号周期的方法,其特征在于,所述方法之后还包括:判断在一段时间内通过极大值与极小值分别获取的周期是否相近;当相近时,则将两者周期的平均值设定为生理信号周期。
- 根据权利要求1所述的获取生理信号周期的方法,其特征在于,所述接收生理信号值与暂存数值比较大小,保留其中之一;将维持时间达到设定时间的生理信号值判定为一个极值;重新开始循环,判定下一个极值的步骤具体包括:接收一个生理信号值,启动计数器a并加一个单位数值,并将所述生理信号值与暂存数值进行比较,当所述生理信号值大于/小于暂存数值时,将所述生理信号值取代暂存数值,并将计数器a中数值累加至累加器b中,清零计数器a;当所述生理信号值小于/大于暂存数值时,继续接收下一个心跳信号电压值;当计数器a中计数达到设定时间所对应的数值,即可判定所述生理信号值为一个极值;则输出累加器b中累加的数值,然后清零计数器a、暂存器以及累加器b,并继续判定下一个极值;所述一个极值以及下一个极值分别为极大值或极小值。
- 根据权利要求3中所述的获取生理信号周期的方法,其特征在于,所述通过计算一个极值至下一个极值之间的时间值,获取生理信号周期的步骤具体包括:将累加器b中累加的数值所需要的时间与设定时间相加,获取所述生理信号周期。
- 根据权利要求1至3中任一项所述的获取生理信号周期的方法,其特征在于,所述设定时间大于生理信号周期识别范围上限的半个周期。
- 一种获取生理信号周期的系统,其特征在于,包括:极值判定单元,用于接收生理信号值与暂存数值比较大小,保留其中之一;将维持时间达到设定时间的生理信号值判定为一个极值;重新开始循环,判定下一个极值;周期计算单元,用于通过计算一个极值至下一个极值之间的时间值,获取生理信号周期。
- 根据权利要求6所述的获取生理信号周期的系统,其特征在于,所述系统还包括:相近周期判断单元,用于判断在一段时间内通过极大值与极小值分别获取的周期是否相近;周期设定单元,用于当相近时,则将两者周期的平均值设定为生理信号周期。
- 根据权利要求6所述的获取生理信号周期的系统,其特征在于,所述极值判定单元具体用于:接收一个生理信号值,启动计数器a并加一个单位数值,并将所述生理信号值与暂存数值进行比较,当所述生理信号值大于/小于暂存数值时,将所述生理信号值取代暂存数值,并将计数器a中数值累加至累加器b中,清零计数器a;当所述生理信号值小于/大于暂存数值时,继续接收下一个心跳信号电压值;当计数器a中计数达到设定时间所对应的数值,即可判定所述生理信号值为一个极值;则输出累加器b中累加的数值,然后清零计数器a、暂存器以及累加器b,并继续判定下一个极值;所述一个极值以及下一个极值分别为极大值或极小值。
- 根据权利要求6中所述的获取生理信号周期的系统,其特征在于,所述周期计算单元具体包括:将累加器b中累加的数值所需要的时间与设定时间相加,获取所述生理信号周期。
- 根据权利要求6至8中任一项所述的获取生理信号周期的系统,其特征在于,所述设定时间大于生理信号周期识别范围上限的半个周期。
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KR1020147020090A KR101635825B1 (ko) | 2012-03-12 | 2013-02-01 | 생체신호주기의 획득 방법 및 시스템 |
EP13760831.1A EP2752154B1 (en) | 2012-03-12 | 2013-02-01 | Method and system for obtaining physiological signal period |
JP2014553602A JP5873574B2 (ja) | 2012-03-12 | 2013-02-01 | 生理信号周期を取得する方法及びシステム |
ES13760831.1T ES2687227T3 (es) | 2012-03-12 | 2013-02-01 | Método y sistema para obtener el período de señal fisiológica |
US14/362,414 US20140336946A1 (en) | 2012-03-12 | 2013-02-01 | Method and system for obtaining cycle of physiological signal |
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CN102613964B (zh) * | 2012-03-12 | 2013-12-25 | 深圳市视聆科技开发有限公司 | 获取生理信号周期的方法及系统 |
KR102031340B1 (ko) * | 2018-03-14 | 2019-10-11 | 주식회사 필로시스 | 혈당 측정 장치, 방법, 및 시스템 |
CN109741829B (zh) * | 2019-01-09 | 2022-10-28 | 哈尔滨理工大学 | 结合三周期判断的胸腹表面区域呼吸信号周期预测方法 |
CN109741830B (zh) * | 2019-01-09 | 2022-12-06 | 哈尔滨理工大学 | 单双周期混合判断的胸腹表面区域呼吸信号周期预测方法 |
CN109741827B (zh) * | 2019-01-09 | 2022-11-01 | 哈尔滨理工大学 | 结合双周期判断的胸腹表面区域呼吸信号周期预测方法 |
KR102371443B1 (ko) | 2020-08-24 | 2022-03-08 | (주)허니냅스 | 인공지능을 이용한 수면단계 분석 자동화 시스템 및 그 동작 방법 |
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- 2013-02-01 WO PCT/CN2013/071291 patent/WO2013135120A1/zh active Application Filing
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US20140336946A1 (en) | 2014-11-13 |
KR101635825B1 (ko) | 2016-07-04 |
KR20140098858A (ko) | 2014-08-08 |
EP2752154A1 (en) | 2014-07-09 |
CN102613964B (zh) | 2013-12-25 |
JP2015508671A (ja) | 2015-03-23 |
EP2752154A4 (en) | 2015-06-03 |
CN102613964A (zh) | 2012-08-01 |
ES2687227T3 (es) | 2018-10-24 |
EP2752154B1 (en) | 2018-07-11 |
JP5873574B2 (ja) | 2016-03-01 |
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