WO2013044420A1 - 离心式转盘 - Google Patents

离心式转盘 Download PDF

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Publication number
WO2013044420A1
WO2013044420A1 PCT/CN2011/001666 CN2011001666W WO2013044420A1 WO 2013044420 A1 WO2013044420 A1 WO 2013044420A1 CN 2011001666 W CN2011001666 W CN 2011001666W WO 2013044420 A1 WO2013044420 A1 WO 2013044420A1
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WO
WIPO (PCT)
Prior art keywords
cover
centrifugal
film
disk body
diluent
Prior art date
Application number
PCT/CN2011/001666
Other languages
English (en)
French (fr)
Inventor
蔡忠宪
蔡晓忠
Original Assignee
保生国际生医股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 保生国际生医股份有限公司 filed Critical 保生国际生医股份有限公司
Priority to CN201190000965.0U priority Critical patent/CN203432978U/zh
Priority to PCT/CN2011/001666 priority patent/WO2013044420A1/zh
Publication of WO2013044420A1 publication Critical patent/WO2013044420A1/zh

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents

Definitions

  • the present invention relates to a centrifugal turntable, and more particularly to a centrifugal turntable suitable for biochemical testing. Background technique
  • Biochemical testing of blood and other specimens usually requires rapid quantitative dispensing of liquids to perform different tests. Biochemical tests also typically require separation of cell bodies and body fluids that may affect each other's detection prior to detection. These steps of quantitative partitioning and separation are usually accomplished by a centrifugation step, and the quantitative samples are dispensed into each sample well by manual or automated means.
  • the above quantitative distribution process is laborious and time consuming. Therefore, automated quantitative distribution systems for various specimens have been proposed to improve this time-consuming process.
  • centrifugal turntable The main improvement of the current automated dosing system is the use of a centrifugal turntable. These centrifugal turntables, after being equipped with a centrifuge, can perform quantitative dispensing of samples, mixing samples and extracting liquids, and then for optical inspection. Even if the centrifugal turntable is designed in a variety of ways, how to perform biochemical tests more conveniently and accurately, the centrifugal turntable still has a lot of room for improvement. Summary of the invention
  • centrifugal turntable which solves the technical problem of improving an existing centrifugal turntable.
  • a centrifugal turntable which includes a disc body, a piercing structure, a cover film, and a cover.
  • the disc body has a diluent container, and the diluent container has a membrane.
  • the piercing structure is located on the sealing film.
  • the cover film covers the diluent container and the piercing structure.
  • the cover body is covered on the cover film and fixed on the disc body, and the cover body has a pressing structure for pressing the piercing structure.
  • the cover is an opaque cover.
  • the opaque cover has a plurality of optical detecting holes.
  • the optical detecting hole is located at a periphery of the opaque cover.
  • the opaque cover has an operating window.
  • the disk body has the same body that is aligned with the operating window.
  • the top surface of the sample cavity is lower than the top surface of the opaque cover.
  • the cover body has a plurality of positioning posts for positioning the cover by inserting corresponding positions of the disk body.
  • the cover has at least one arc or a closed annular fuse, whereby it is fixed to the disc by heat.
  • the disk body has a bottom hole for a drive rotor to be inserted Raise the diluent container.
  • the centrifugal dial of the present invention utilizes the newly added cover design to not only provide a function of pressing against the piercing structure, but also limit the detection beam entering the range through the optical detecting hole to improve the accuracy of the optical detection.
  • the closed annular fuse line design of the cover also helps prevent leakage or spillage of the test sample from contaminating the centrifuge or biochemical test equipment.
  • FIG. 1 is a side elevational view of a centrifugal carousel in accordance with an embodiment of the present invention.
  • 2 is a perspective view showing a cover body of the centrifugal type turntable of FIG. 1.
  • Figure 3 is a plan view showing the cover of Figure 2;
  • Figure 4 is a cross-sectional view of the cover of Figure 3 taken along line 4 - 4'.
  • FIG. 1 is a side view of a centrifugal turntable according to an embodiment of the present invention.
  • Centrifugal turntable 100 is suitable for biochemical testing of fashion filling and dispensing test samples, and it is necessary to cooperate with centrifugal equipment and biochemical testing equipment ( ⁇ on the drawing surface).
  • the centrifugal turntable 100 Ji includes a disk body 102, a diluent container 106 (containing a diluent), a piercing structure 107, a cover film 109, and a cover 110.
  • the upper half of the driving rotor 108 is combined with the disc body 102, and the lower half is used for combination with the centrifugal device, so that the centrifugal device can drive the centrifugal dial 100 to rotate, thereby performing quantitative dispensing of the specimen, mixing of the specimen and Diluent or separate functions such as cell body and body fluids.
  • the disc body 102 has a diluent container 106 (containing a diluent) therein.
  • the diluent container 106 has a sealing film 106a (for example, an aluminum film) to seal the opening of the container to protect the contained diluent from volatilization or contamination.
  • the disc body 102 has a bottom hole 102b for driving the rotor 108 (the central shaft portion) to be inserted for lifting dilution Liquid container 106.
  • the structure 107 is placed on the sealing film 106a to pierce the sealing film 106a when needed, so that the diluent in the diluent container 106 can flow out.
  • the puncture structure 107 pierces the seal film 106a to allow the diluent to flow out.
  • the sealing film 109 covers the diluent container 106 and the puncturing structure 107, thereby positioning the diluent container 106 and the puncturing structure 107 in the disk body 102.
  • the cover body 110 covers the cover film 109 and is fixed on the disc body 102. The function of the bird is to press the piercing structure 107, and when the diluent container 106 is lifted up, the piercing structure 107 can pierce the sealing film. 106a.
  • the cover 110 may be an opaque cover (but not limited to a opaque cover).
  • the cover 110 has an operating window 110c (i.e., a through hole) aligned with the sample cavity 105 on the disk body 102 to allow a person performing biochemical testing to incorporate the sample into the sample cavity 105 through the operating window 110.
  • the top surface 105a of the sample cavity 105 should be lower than the top surface 110f of the cover 110.
  • the cover 110 has a plurality of positioning posts 110a, so that the relative positions of the cover 110 and the disk body 102 can be accurately determined by inserting the corresponding positions of the disk body 102.
  • FIG. 1 is a perspective view showing a cover body of the centrifugal type turntable of FIG. 1.
  • Figure 3 is a plan view showing the cover of Figure 2;
  • the cover 110 has a plurality of optical sensing apertures 110b that are aligned with the sample slots on the disk body 102.
  • the learning detecting hole is located at the periphery of the cover 110, but is not limited thereto.
  • the optical detection hole 110b has a function of restricting the entrance of the detection beam, so that the light beam passing through the sample slot will only come from the light beam passing through the optical detection hole 110b, preventing the unidentified stray beam from entering the sample. In the tank, it affects the result of the test.
  • the center of the cover 110 has a press structure 110d for resisting the piercing structure 107, and when the diluent container 106 is lifted upward, the piercing structure 107 can pierce the sealing film 106a (please refer to Fig. 1 at the same time).
  • the press-fit structure 110d is a trademark of Mercedes-Benz, but is not limited to this shape, as long as it can appropriately resist the shape of the piercing structure, for example, a plurality of Concentric circle, ellipse, etc.
  • the opening shape of the operation window 110c is an approximate peanut shape, but is not limited to this shape.
  • FIG. 4 is a cross-sectional view of the cover body of FIG. 3 along 4-4.
  • This figure is a design showing the edge of the cover 110.
  • the cover body 110 has a fuse line 110e for fixing the cover body 110 to the disk body 102 by heating (for example, using a high-frequency heating method).
  • the fuse line 110e is preferably a closed ring shape that surrounds the edge of the cover 110 so that the edge of the cover 110 can be tightly fixed to the disk body 102.
  • the fuse line 110e may also be one or more curved (or referred to as a notched ring), surrounding the side of the cover 110
  • the edge enables the edge of the cover 110 to be fixed to the disk body 102. If the test sample leaks or overflows as described above, the sample liquid remaining between the cover 110 and the cover film 109 is restricted by the wall formed by the closed fuse line when it is rapidly rotated. It is contaminated by centrifugal equipment or biochemical testing equipment.
  • the cover 110 has a positioning post 110a for facilitating alignment of the relative positions of the cover 110 and the disc body 102, and then the edge of the cover 110 can be fixed to the disc body 102.
  • the centrifugal turntable of the present invention utilizes the newly added cover design to not only provide a function of resisting the piercing structure, but also limit the detection beam entering the range through the optical detection hole to enhance the optical. The accuracy of the test.
  • the closed annular fuse line design of the cover also helps prevent spilled or spilled test samples from contaminating the centrifuge or biochemical test equipment.

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  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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Abstract

一种离心式转盘（100）包括一圆盘体（102）、一刺破结构（107）、一封盖膜（109）以及一盖体（110）。圆盘体具有一稀释液容器（106），稀释液容器具有一封膜（106a），以便密封容器开口，使内含的稀释液免于挥发或受污染。刺破结构位于封膜上，用以在需求时刺破封膜，而使稀释液容器内的稀释液能够流出。封盖膜覆盖于容器及刺破结构上。盖体覆盖于封盖膜上且固定于圆盘体上，盖体具有一压合结构（110d），以便抵压刺破结构，使其较容易刺破封膜。

Description

离心式转盘 技术领域
本发明是有关于一种离心式转盘， 且特别是有关于一种适用于生化检 测的离心式转盘。 背景技术
血液及其他检体的生化检测通常需要液体能迅速的定量分配， 以执行 不同检测。 生化检测通常也需要将可能彼此影响检测的细胞体与体液能在 检测前分离。 这些定量分配及分离的步驟通常是借离心步骤来达成， 再借 由人工或自动方式将定量的检体分配到各样本槽内。 上述定量分配流程不 但费工， 而且耗时。 因此， 各种检体的自动化定量分配系统纷纷被提出以 改善这费工耗时流程。
目前自动化定量分配系统主要的改进在于使用离心式转盘。 这些离心 式转盘在搭配离心机后， 能执行检体的定量分配、 混合样本与吸释液等工 作， 而后供光学检测之用。 即使离心式转盘设计多种， 但如何能更方便、 更 精确的进行生化检测， 目前离心式转盘仍然有很多改善空间。 发明内容
因此， 本发明的一目的是在于， 提供一种离心式转盘， 所要解决的技 术问题是， 改善现有的离心式转盘。
根据上述本发明的目的， 提供一种离心式转盘， 其包含一圓盘体、 一 刺破结构、 一封盖膜以及一盖体。 圆盘体具有一稀释液容器， 稀释液容器 具有一封膜。 刺破结构位于封膜上。 封盖膜覆盖于稀释液容器及刺破结构 上。 盖体覆盖于封盖膜上且固定于圓盘体上， 盖体具有一压合结构， 借以 抵压刺破结构。
依据本发明另一实施例， 盖体是一不透光盖体。
依据本发明另一实施例 , 不透光盖体具有多个光学检测孔。
依据本发明另一实施例， 上述光学检测孔位于不透光盖体的周缘。 依据本发明另一实施例， 不透光盖体具有一操作窗。
依据本发明另一实施例， 圆盘体具有一样本腔体， 其位置对准操作窗。 依据本发明另一实施例， 样本腔体的顶面低于不透光盖体的顶面。 依据本发明另一实施例， 盖体具有多根定位柱， 借以插入圆盘体对应 的位置而定位盖体。
依据本发明另一实施例， 盖体具有至少一弧形或者一封闭环形的导熔 线， 借以经加热固定于该圆盘体上。
依据本发明另一实施例， 圓盘体具有一底孔， 供一驱动转子插入以举 升该稀释液容器。
由上述可知， 应用本发明的离心式转盘， 利用其新增的盖体设计， 不 但对于刺破结构提供抵压的功能， 也透过光学检测孔限制检测光束进入范 围而提升光学检测的准确性。 此外， 盖体的封闭环形的导熔线设计， 也有 助于防止漏出或溢出的检测样本对离心设备或生化检测设备造成污染。 附图的简要说明
为让本发明的上述和其他目的、 特征、 优点与实施例能更明显易 懂， 所附图式的说明如下：
图 1是绘示依照本发明一实施例的一种离心式转盘的侧视图。 图 2是绘示图 1的离心式转盘其中的盖体的立体图。
图 3是绘示图 2的盖体的平面图。
图 4是绘示图 3的盖体沿 4- 4' 的剖面图。
【主要元件符号说明】
100离心式转盘 102圆盘体
105样本腔体 105a顶面
106稀释液容器 106a封膜
107刺破结构 108驱动转子
109封盖膜 110盖体
110a定位柱 110b光学检测孔
110c操作窗 110d压合结构
110e导熔线 11 Of 顶面 实现发明的最佳方式
为更进一步阐述本发明为达成预定发明目的所采取的技术手段及功 效，以下结合附图及较佳实施例，对依据本发明提出的离心式转盘其具体实 施方式、 结构、 特征及功效， 详细说明如后。
请参照图 1, 其^依照本发明一实施例的一种离心式转盘的侧视图。 离 心式转盘 100适用于生化检测时装填与分配检测样品， 需配合离心设备及 生化检测设备（ ^于图面)。 离心式转盘 100 Ji包含一圆盘体 102、 稀 释液容器 106 (内含稀释液）、 刺破结构 107、 封盖膜 109及盖体 110等元 件。 驱动转子 108的上半部用以与圆盘体 102组合， 而下半部用以与离心 设备组合， 因此离心设备能够驱动离心式转盘 100旋转， 因而能执行定量 分配检体、 混合检体与稀释液或分离细胞体与体液等功能。 圆盘体 102 内 具有一稀释液容器 106 (内含稀释液）。 稀释液容器 106具有封膜 106a (例 如铝膜）， 借以密封容器开口， 使内含的稀释液免于挥发或受污染。 圆盘体 102具有一底孔 102b， 可供驱动转子 108 (中心承轴部份）插入以举升稀释 液容器 106。 构 107置于封膜 106a上， 用以在需求时刺破封膜 106a， 而 使稀释液容器 106内的稀释液能够流出。 当圆盘体 102与驱动转子 108组 合而使稀释液容器 106向上举升时， 刺破结构 107会刺破封膜 106a， 而使 稀释液能够流出。 封差膜 109覆盖于稀释液容器 106及刺破结构 107上， 借 以定位稀释液容器 106及刺破结构 107在圓盘体 102内。 盖体 110覆盖于 封盖膜 109上且固定于圓盘体 102上 其功禽 一就是抵压刺破结构 107， 而 使稀释液容器 106向上举升时， 刺破结构 107能够刺破封膜 106a。
在本实施例中， 盖体 110可以是一不透光盖体（但不限定是不透光盖 体）。 盖体 110上具有一操作窗 110c (即一通孔）对准圆盘体 102上的样本 腔体 105， 让执行生化检测的人能够通过操作窗 110将检体加入样本腔体 105内。 在本实施例中， 当盖体 110与圆盘体 102组合后， 样本腔体 105的 顶面 105a应低于盖体 110的顶面 110f。即使在检体加入样本腔体 105的过 程中有漏出或溢出的液体， 较不易扩及盖体 110 的顶面， 造成漏出或溢出 的液体在后续离心式转盘快速旋转时甩出而对离心设备或生化检测设备造 成污染。
此外， 盖体 110具有多根定位柱 110a， 借以插入圆盘体 102对应的位 置而使盖体 110与圓盘体 102两者的相对位置能够准确。
请同时参照图 2和图 3， 图 1是绘示图 1的离心式转盘其中的盖体的 立体图。 图 3是绘示图 2的盖体的平面图。 盖体 110具有多个光学检测孔 110b, 其位置对准圓盘体 102 上的样本槽。 在本实施例中， 因样本槽位于 圓盘体 102的周缘， 学检测孔位于盖体 110的周缘，但并不局限于此。 当 盖体 110为一不透光盖体时， 光学检测孔 110b具有限制检测光束进入的作 用， 使通过样本槽的光束只会来自通过光学检测孔 110b的光束， 避免不明 杂散光束射入样本槽内而影响检测的结果。
盖体 110的中心具有压合结构 110d， 借以抵压刺破结构 107 , 而使稀 释液容器 106向上举升时， 刺破结构 107能够刺破封膜 106a (请同时参照 图 1 )。 在本实施例中， 压合结构 110d为一类^ (宾士车 （Mercedes-Benz ) 的商标， 但并不局限于此形状， 只要能适当抵压刺破结构的形状均可， 例 如多个同心圓、 椭圆等。 在本实施例中， 操作窗 110c的开孔形状为一近似 花生外形， 但并不局限于此形状。
请参照图 4， 其绘示图 3 的盖体沿 4-4， 的剖面图。 此图是绘示盖体 110的边缘的设计。 在盖体 110右侧的放大图中， 盖体 110具有一导熔线 110e , 借以经加热 （例如使用高周波的加热方式） 而使盖体 110 固定于圓 盘体 102上。 在本实施例中， 导熔线 110e较佳为一封闭的环形， 环绕盖体 110的边缘， 使得盖体 110的边缘能紧密固定于圆盘体 102上。 此外， 导熔 线 110e亦可为一或多个弧形 （或称为有缺口的环形）， 环绕盖体 110的边 缘， 使得盖体 110的边缘能固定于圆盘体 102上。 若有如上述的检测样本 漏出或溢出的情形时， 存留于盖体 110与封盖膜 109之间的样本液体在快 速旋转时， 会被封闭导熔线所形成的档墙所限制， 而不会被甩出而对离心 设备或生化检测设备造成污染。 此外， 盖体 110具有定位柱 110a , 方便使 盖体 110与圆盘体 102的相对位置能够对准， 再接着盖体 110的边缘能固 定于圓盘体 102上。
在执行上述检体的定量分配、 混合样本与吸释液等功能时， 圓盘体内 需要样本槽、 流道、 混合槽等设计， 因非本发明改良的重点且各制造商设 计各有不同， 故在说明书中不多加赘述。
由上述本发明实施方式可知， 应用本发明的离心式转盘， 利用其新增 的盖体设计， 不但对于刺破结构提供抵压的功能， 也透过光学检测孔限制 检测光束进入范围而提升光学检测的准确性。 此外， 盖体的封闭环形的导 熔线设计， 也有助于防止漏出或溢出的检测样本对离心设备或生化检测设 备造成污染。
以上所述， 仅是本发明的较佳实施例而已， 并非对本发明作任何形式 上的限制， 虽然本发明已以较佳实施例揭露如上， 然而并非用以限定本发 明， 任何熟悉本专业的技术人员在不脱离本发明技术方案范围内， 当可利 用上述揭示的技术内容作出些许更动或修饰为等同变化的等效实施例， 但 凡是未脱离本发明技术方案的内容， 依据本发明的技术实质对以上实施例 所作的任何简单修改、 等同变化与修饰，均仍属于本发明技术方案的范围 内。

Claims

权 利 要 求
1、 一种离心式转盘， 其特征在于包含：
一圆盘体， 具有一稀释液容器， 该稀释液容器具有一封膜；
一刺破结构， 位于该封膜上；
一封盖膜， 覆盖于该稀释液容器及该刺破结构上； 以及
一盖体， 覆盖于该封盖膜上且固定于该圆盘体上， 该盖体具有一压合 结构， 借以抵压该刺破结构。
2、 如权利要求 1所述的离心式转盘， 其特征在于其中该盖体是一不透 光盖体。
3、 如权利要求 2所述的离心式转盘， 其特征在于其中该不透光盖体具 有多个光学检测孔。
4、 如权利要求 3所述的离心式转盘， 其特征在于其中上述光学检测孔 位于该不透光盖体的周缘。
5、 如权利要求 2所述的离心式转盘， 其特征在于其中该不透光盖体具 有一操作窗。
6、 如权利要求 5所述的离心式转盘， 其特征在于其中该圆盘体具有一 样本腔体， 其位置对准该操作窗。
7、 如权利要求 6所述的离心式转盘， 其特征在于其中该样本腔体的顶 面低于该不透光盖体的顶面。
8、 如权利要求 1所述的离心式转盘， 其特征在于其中该盖体具有多根 定位柱， 借以插入该圓盘体对应的位置而定位该盖体。
9、 如权利要求 1所述的离心式转盘， 其特征在于其中该盖体具有至少 一弧形或一封闭环形的导熔线， 借以经加热固定于该圓盘体上。
1 0、 如权利要求 1所述的离心式转盘， 其特征在于其中该圆盘体具有 一底孔， 供一驱动转子插入以举升该稀释液容器。
PCT/CN2011/001666 2011-09-30 2011-09-30 离心式转盘 WO2013044420A1 (zh)

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