WO2013002561A3 - 키타사토스포라 속 dg09 균주 및 이를 이용하여 5,6-디히드록시인돌을 생산하는 방법 - Google Patents

키타사토스포라 속 dg09 균주 및 이를 이용하여 5,6-디히드록시인돌을 생산하는 방법 Download PDF

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Publication number
WO2013002561A3
WO2013002561A3 PCT/KR2012/005099 KR2012005099W WO2013002561A3 WO 2013002561 A3 WO2013002561 A3 WO 2013002561A3 KR 2012005099 W KR2012005099 W KR 2012005099W WO 2013002561 A3 WO2013002561 A3 WO 2013002561A3
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WIPO (PCT)
Prior art keywords
strain
kitasatospora
dihydroxyindole
producing
same
Prior art date
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PCT/KR2012/005099
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English (en)
French (fr)
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WO2013002561A2 (ko
Inventor
이동걸
강희철
한상근
이찬우
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지에프씨(주)
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Publication date
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Priority to EP12804322.1A priority Critical patent/EP2727995A4/en
Publication of WO2013002561A2 publication Critical patent/WO2013002561A2/ko
Publication of WO2013002561A3 publication Critical patent/WO2013002561A3/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/18Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
    • C12Y114/18001Tyrosinase (1.14.18.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Abstract

본 발명은 키타사토스포라 속 DG09 균주, 이로부터 생산되는 티로시나제, 및 이를 이용하여 5,6-디히드록시인돌을 생산하는 방법에 관한 것이다. 보다 구체적으로, 본 발명은 토양에서 분리한 키타사토스포라 속 DG09 균주, 상기 균주가 생산하는 티로시나제, 및 이를 이용하여 5,6-디히드록시인돌을 생산하는 방법에 관한 것이다.
PCT/KR2012/005099 2011-06-28 2012-06-28 키타사토스포라 속 dg09 균주 및 이를 이용하여 5,6-디히드록시인돌을 생산하는 방법 WO2013002561A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP12804322.1A EP2727995A4 (en) 2011-06-28 2012-06-28 STRAIN KITASATOSPORA SP. DG09 AND PROCESS FOR PRODUCING 5,6-DIHYDROXYINDOLE USING THE SAME

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0063137 2011-06-28
KR1020110063137A KR101099666B1 (ko) 2011-06-28 2011-06-28 키타사토스포라 속 dg09 균주 및 이를 이용하여 5,6-디히드록시인돌을 생산하는 방법

Publications (2)

Publication Number Publication Date
WO2013002561A2 WO2013002561A2 (ko) 2013-01-03
WO2013002561A3 true WO2013002561A3 (ko) 2013-02-28

Family

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PCT/KR2012/005099 WO2013002561A2 (ko) 2011-06-28 2012-06-28 키타사토스포라 속 dg09 균주 및 이를 이용하여 5,6-디히드록시인돌을 생산하는 방법

Country Status (3)

Country Link
EP (1) EP2727995A4 (ko)
KR (1) KR101099666B1 (ko)
WO (1) WO2013002561A2 (ko)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050109172A (ko) * 2004-05-14 2005-11-17 서주원 항암물질을 생산하는 희귀 방선균 키타사토스포라엠제이엠-383과 생산물의 제조방법.
KR100724770B1 (ko) * 2006-01-27 2007-06-04 한국생명공학연구원 아실 호모세린 락톤의 경쟁적 저해활성을 가지는키타사토스포라 속 ar030054
JP2011046658A (ja) * 2009-08-27 2011-03-10 Gekkeikan Sake Co Ltd メラニン前駆体含有溶液及びその製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009025761A2 (en) * 2007-08-17 2009-02-26 Massachusetts Institute Of Technology Methods for identifying bacterial strains that produce l-tyrosine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050109172A (ko) * 2004-05-14 2005-11-17 서주원 항암물질을 생산하는 희귀 방선균 키타사토스포라엠제이엠-383과 생산물의 제조방법.
KR100724770B1 (ko) * 2006-01-27 2007-06-04 한국생명공학연구원 아실 호모세린 락톤의 경쟁적 저해활성을 가지는키타사토스포라 속 ar030054
JP2011046658A (ja) * 2009-08-27 2011-03-10 Gekkeikan Sake Co Ltd メラニン前駆体含有溶液及びその製造方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GROTH, I. ET AL., INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol. 54, 2004, pages 2121 - 2129, XP055105421 *
See also references of EP2727995A4 *

Also Published As

Publication number Publication date
EP2727995A2 (en) 2014-05-07
KR101099666B1 (ko) 2011-12-29
WO2013002561A2 (ko) 2013-01-03
EP2727995A4 (en) 2014-12-17

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